Abstract: Provided are humanized monoclonal antibodies against protein, programmed cell death ligand-1 (PD-L1), the methods of hybridoma generation using SD rats, the nucleic acid molecules encoding the anti-PD-L1 antibodies, expression vectors and host cells used for the expression of anti-PD-L1 antibodies. Also provided are the methods for validating the function of antibodies in vitro.

Abstract: The present application provides mask plate, fabrication method thereof, and mask plate assembly. The mask plate includes two opening areas being respectively on different sides of mask pattern area along first direction, and two welding areas. One welding area is on a side of one opening area away from the mask pattern area along first direction, and the other welding area is on a side of the other opening area away from mask pattern area along first direction. Evaporation holes are arranged in mask unit, buffer holes are arranged in each opening area, and ratio of maximum dimension of buffer hole in any direction in plane where the mask plate is located to maximum dimension of evaporation hole in the direction is greater than 100. Buffer holes are distributed at equal intervals along a second direction, and second direction is in the plane and is perpendicular to first direction.

Abstract: A dual-band HP omnidirectional antenna includes an electrically small (ES) first omnidirectional loop antenna for a first band, and a second omnidirectional loop antenna for a second band. The first omnidirectional loop antenna and the second omnidirectional loop antenna are capable of operating independently in the first band and the second band. A loading effect of the second omnidirectional loop antenna adapted to suppress a higher-order mode of the first omnidirectional loop antenna.

Abstract: Embodiments provide an ear pad having an annular structure. The ear pad includes an inner layer and an outer layer covering the inner layer. The inner layer and the outer layer are separate of annular structures and are separated by a first medium layer. The inner layer coats a second medium layer. Acoustic impedance of the first medium layer is different from acoustic impedance of the inner layer and the outer layer. The ear pad is configured to close a front cavity space between a housing and an ear of a user, thereby preventing sound leakage and reducing external noise entering the ear of the user. Various ear pad embodiments provide a double-layer structure including the inner layer and the outer layer separated by the first medium layer.

Abstract: An input method and a smart terminal device. After a processor in the smart terminal device determines, based on a first detection solution of a first infrared sensor, that a target object enters or leaves a first space range from a first plane, the processor starts or stops displaying a cursor based on distances measured by ultrasonic sensors; and after the processor determines, based on a second detection result of a second infrared sensor, that the target object enters or leaves a second space range from a second plane, the processor starts or stops performing a confirmation operation based on a location of the cursor.

Abstract: The present invention provides PD-1 monoclonal antibodies, particularly human monoclonal antibodies of PD-1, which specifically bind to PD-1 with high affinity and comprise a heavy chain and a light chain. The present invention further provides nucleic acid sequence encoding the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Immunoconjugates, therapeutic compositions comprising the antibodies of the invention are also provided. The invention also provides methods for treating various cancers with anti-PD-1 antibodies.

Abstract: Embodiments of this application disclose a noise reduction headset. A branch pipe is disposed in the headset to connect a sound cavity inside the headset and an external environment. The branch pipe has a low-pass filter function to filter out high-band noise entering the sound cavity from the external environment, so that impact on sound quality inside the sound cavity that is caused by noise in the external environment is reduced, thereby implementing passive noise reduction.

Abstract: Bispecific antibodies comprising a first targeting moiety which specifically binds to PD-1 and a second targeting moiety which specifically binds to LAG-3, wherein the first targeting moiety comprises a first VHH domain and the second targeting moiety comprises a second VHH domain. Amino acid sequences of the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Therapeutic compositions comprising the antibodies of the invention are also provided and methods for treating cancers and other diseases with the bispecific antibodies.

Abstract: Disclosed are an unmanned distribution system and method. By means of the system, a temporary storage facility can be arranged at a preset location of a closed distribution area, for example, a corresponding temporary storage facility is arranged near a closed housing estate, community or unit; an external item to be distributed that needs to be distributed is received and temporarily stored by the arranged temporary storage facility; and a robot arranged inside the closed distribution area can obtain the item to be distributed from the temporary storage facility and distribute the item to be distributed within the closed distribution area.

Abstract: Disclosed is a charging barrel of an infrared dehumidification, crystallization and drying all-in-one machine and a drying machine.

Abstract: The present invention relates to the field of therapeutic monoclonal antibodies, and specifically provides an anti-FXI/FXIa antibody or an antigen-binding fragment thereof, nucleic acid molecules encoding same, and methods for preparing same. The anti-FXI/FXIa antibody or antigen-binding fragment thereof described in the present invention has specificity and high affinity to FXI/FXIa, and can effectively inhibit the activity of FXI/FXIa. Therefore, the present invention further provides a pharmaceutical composition comprising the antibody or antigen-binding fragment thereof, and a use thereof in the preparation of a drug which is used for the prevention and/or treatment of diseases or disorders related to coagulation or thromboembolism.

Abstract: The disclosure relates to a tie resin formulation with excellent adhesion to polyethylene terephthalate (PET). The resin includes (A) an ethylene acrylate copolymer formed from ethylene and alkyl acrylate, where the ethylene acrylate copolymer has an acrylate content of 10 to 30 weight percent and an ethylene content of 90 to 70 weight percent based on the total weight of the ethylene acrylate copolymer and the acrylate content and (B) a transesterification catalyst; where the resin includes: 30 to 99.999 weight percent of the ethylene acrylate copolymer based on the total weight of the resin; 0.001 to 10 weight percent of the transesterification catalyst based on the total weight of the resin; and (C) 0 to 69.999 of a non-polar polyolefin based on the total weight of the resin.

Abstract: Provided are a goods picking system and a goods picking system method, the system includes: a plurality of carrying robots; a plurality of racks used for storing goods and being carried by the plurality of carrying robots, where in a rack area, the plurality of racks are arranged in a rack array with a plurality of rows and a plurality of columns, and empty rows or columns constitute channels for the plurality of carrying robots to pass; and at least some of the plurality of racks are blocked racks which are not adjacent to any channel instead of being surrounded by other racks and racks except the blocked racks are referred to as unblocked racks; rack-moving robots, which are operable based on instructions of a control system to move racks in the rack area so as to change a certain blocked rack into an unblocked rack; operating positions.

Abstract: A display panel, a mask used for evaporation, a mask assembly and a manufacturing method thereof are provided. The display panel includes: a base substrate; and a display area and a peripheral area; wherein, the peripheral area is provided with two types of dummy sub-pixel units, each type of dummy sub-pixel unit includes a dummy light-emitting material layer and a dummy auxiliary light-emitting layer, wherein, a first structure layer of a first dummy light-emitting material layer and a first dummy auxiliary light-emitting layer is arranged in the same layer as a second structure layer of a second dummy light-emitting material layer and a second dummy auxiliary light-emitting layer, and at least one of a size and a shape of an orthographic projection of the second structure layer on the base substrate is different from that of an orthographic projection of the first structure layer on the base substrate.

Abstract: An audio data transmission method. An electronic device transmits audio data to a first earbud of a TWS headset by using a first CIS of a first CIG, and transmits audio data to a second earbud of the TWS headset by using a second CIS of the first CIG. The electronic device determines that the TWS headset is switched from a double-earbud mode (namely, a mode in which the first earbud and the second earbud are used together as audio input/output devices of the electronic device) to a first single-earbud mode (namely, a mode in which the first earbud is independently used as an audio input/output device of the electronic device). In response to the determining, the electronic device deactivates the second CIS, stops transmitting audio data to the second earbud by using the second CIS, and continues transmitting audio data to the first earbud by using the first CIS.

Abstract: Method and apparatus for reducing resource consumption in container image management. Embodiments include receiving directory information and checksum information corresponding to a plurality of files of a container image. Embodiments include determining, based on the directory information and the checksum information, whether each file of the plurality of files is present in a repository. For each respective file of the plurality of files that is determined to be present in the repository, embodiments include updating a file list for the container image to indicate a respective location in the repository of the respective file. For each given file of the plurality of files that is determined not to be present in the repository, embodiments include storing the given file at a given location in the repository and updating the file list for the container image to indicate the given location in the repository of the given file.

Abstract: The present disclosure provides a computer-implemented method, computer system and computer program product for application containerization. According to the computer-implemented method, an application to be containerized can be traced. Information obtained in the tracing can be analyzed to determine one or more features of the application. An image template for the application can be created based on the one or more features. Then, a container image for the application can be built based on the image template.

Abstract: An article package filling method, comprising: selecting a packaging container for an order article in an order container; picking out the order article from the order container and putting same into the packaging container; and injecting a filling medium into a filling space of the packaging container by using a filling equipment, wherein the filling medium has a specific shape before being injected into the filling space, and can form a spatial shape consistent with that of the filling space after being injected into the filling space. According to the filling method, various specifications or types of packaging containers storing the order articles can be filled, so that the supporting and protecting effects on the order articles are implemented, and the package filling efficiency and applicability are improved.

Abstract: An electronic device establishes a first Bluetooth connection to a first wireless earbud, where there is a wireless connection between the first wireless earbud and a second wireless earbud. The electronic device establishes a second Bluetooth connection to the second wireless earbud by using the first wireless earbud. The electronic device simultaneously maintains the first Bluetooth connection and the second Bluetooth connection.