Abstract: The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells.

Abstract: The present disclosure provides resins that can be used as a tie layer in a multilayer structure and to multilayer structures comprising one or more tie layers formed from such resins. In one aspect, a resin for use as a tie layer in a multilayer structure comprises a first composition, wherein the first composition comprises at least one ethylene-based polymer and wherein the first composition comprises a MWCDI value greater than 0.9, and a melt index ratio (I10/I2) that meets the following equation: I10/I2?7.0?1.2×log (I2), wherein the first composition comprises 1 to 99 weight percent of the resin; and a maleic anhydride grafted polyethylene comprising a maleic anhydride grafted high density polyethylene, a maleic anhydride grafted linear low density polyethylene, a maleic anhydride grafted polyethylene elastomer, or a combination thereof, wherein the maleic anhydride grafted polyethylene comprises 1 to 99 weight percent of the resin.

Abstract: A method for monitoring defects of a product implemented in an electronic device obtains product data in real time and determines whether a product is defective based on the product data; when the product is defective, outputting first warning information based on the number of defects of the product which satisfy a first preset condition; obtaining a rate of defects of the product every first preset time period, and outputting second warning information based on the rate of defects of the product when the rate of defects satisfies at least one of a second, third, and fourth preset conditions; when any warning information is output, analyzing distribution of the defects of the product; and predicting at least one cause of each defect of the product according to historical maintenance data of the product and a self-learning record of the electronic device.

Abstract: Provided are a warehousing management system and method. The system includes: a control server, an inventory container, an access device, a temporary container, a workstation and a carrying device. The control server is configured to, in response to a current task, determine a first target inventory container in which a target storage container hit by the current task is located, a first target access device, a target temporary container, a target workstation, and a first target carrying device, and control the first target access device to take out the target storage container from the first target inventory container, carry and store the target storage container to the target temporary container; and control the first target carrying device to move the target temporary container to the target workstation for operation.

Abstract: The present invention provides PD-1 monoclonal antibodies, particularly human monoclonal antibodies of PD-1, which specifically bind to PD-1 with high affinity and comprise a heavy chain and a light chain. The present invention further provides nucleic acid sequence encoding the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Immunoconjugates, therapeutic compositions comprising the antibodies of the invention are also provided. The invention also provides methods for treating various cancers with anti-PD-1 antibodies.

Abstract: Disclosed are a kitchen waste treatment system and a method thereof. The kitchen waste treatment system includes a control module, a drying module, an air extraction module, a grinding module and a temperature sensor all connected with the control module. The control module is for sending a first control signal, a second control signal and a third control signal according to a current working process in a determination that it is turned on normally. The drying module is for drying kitchen waste. The air extraction module is for extracting air from the kitchen waste. The grinding module is for grinding the kitchen waste. The temperature sensor is for detecting a temperature of the drying module. The control module is further for sending a stop command to the drying module in a determination that the temperature is higher than a preset temperature threshold.

Abstract: In one embodiment, a sliding track of a user is detected on a shortcut touchpad of user equipment to identify a sliding direction of the sliding track. The sliding direction is matched to an interaction interface of the user equipment. One or more objects, such as an icon or an input box, are determined on a touch display screen of the user equipment based on the sliding direction of the sliding track entered by the user. The shortcut touchpad may be made to be relatively small, facilitating a one-hand operation of the user and improving user experience.

Abstract: A method of preparing an aqueous dispersion of an ethylene-carboxylic acid copolymer according to exemplary embodiments of the present invention includes: mixing 30% by weight or more of an ethylene-(meth)acrylic acid copolymer, a basic compound, and water to form a mixed solution; and adding an inorganic salt compound to the mixed solution. Therefore, the aqueous dispersion of the ethylene-carboxylic acid copolymer may be effectively dispersed.

Abstract: Embodiments of the present disclosure generally relate to apparatus, systems, and methods for in-situ film growth rate monitoring. A thickness of a film on a substrate is monitored during a substrate processing operation that deposits the film on the substrate. The thickness is monitored while the substrate processing operation is conducted. The monitoring includes directing light in a direction toward a crystalline coupon. The direction is perpendicular to a heating direction. In one implementation, a reflectometer system to monitor film growth during substrate processing operations includes a first block that includes a first inner surface. The reflectometer system includes a light emitter disposed in the first block and oriented toward the first inner surface, and a light receiver disposed in the first block and oriented toward the first inner surface. The reflectometer system includes a second block opposing the first block.

Abstract: Provided are humanized monoclonal antibodies against protein, programmed cell death ligand-1 (PD-L1), the methods of hybridoma generation using SD rats, the nucleic acid molecules encoding the anti-PD-L1 antibodies, expression vectors and host cells used for the expression of anti-PD-L1 antibodies. Also provided are the methods for validating the function of antibodies in vitro.

Abstract: The present application provides mask plate, fabrication method thereof, and mask plate assembly. The mask plate includes two opening areas being respectively on different sides of mask pattern area along first direction, and two welding areas. One welding area is on a side of one opening area away from the mask pattern area along first direction, and the other welding area is on a side of the other opening area away from mask pattern area along first direction. Evaporation holes are arranged in mask unit, buffer holes are arranged in each opening area, and ratio of maximum dimension of buffer hole in any direction in plane where the mask plate is located to maximum dimension of evaporation hole in the direction is greater than 100. Buffer holes are distributed at equal intervals along a second direction, and second direction is in the plane and is perpendicular to first direction.

Abstract: A dual-band HP omnidirectional antenna includes an electrically small (ES) first omnidirectional loop antenna for a first band, and a second omnidirectional loop antenna for a second band. The first omnidirectional loop antenna and the second omnidirectional loop antenna are capable of operating independently in the first band and the second band. A loading effect of the second omnidirectional loop antenna adapted to suppress a higher-order mode of the first omnidirectional loop antenna.

Abstract: Embodiments provide an ear pad having an annular structure. The ear pad includes an inner layer and an outer layer covering the inner layer. The inner layer and the outer layer are separate of annular structures and are separated by a first medium layer. The inner layer coats a second medium layer. Acoustic impedance of the first medium layer is different from acoustic impedance of the inner layer and the outer layer. The ear pad is configured to close a front cavity space between a housing and an ear of a user, thereby preventing sound leakage and reducing external noise entering the ear of the user. Various ear pad embodiments provide a double-layer structure including the inner layer and the outer layer separated by the first medium layer.

Abstract: An input method and a smart terminal device. After a processor in the smart terminal device determines, based on a first detection solution of a first infrared sensor, that a target object enters or leaves a first space range from a first plane, the processor starts or stops displaying a cursor based on distances measured by ultrasonic sensors; and after the processor determines, based on a second detection result of a second infrared sensor, that the target object enters or leaves a second space range from a second plane, the processor starts or stops performing a confirmation operation based on a location of the cursor.

Abstract: The present invention provides PD-1 monoclonal antibodies, particularly human monoclonal antibodies of PD-1, which specifically bind to PD-1 with high affinity and comprise a heavy chain and a light chain. The present invention further provides nucleic acid sequence encoding the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Immunoconjugates, therapeutic compositions comprising the antibodies of the invention are also provided. The invention also provides methods for treating various cancers with anti-PD-1 antibodies.

Abstract: Embodiments of this application disclose a noise reduction headset. A branch pipe is disposed in the headset to connect a sound cavity inside the headset and an external environment. The branch pipe has a low-pass filter function to filter out high-band noise entering the sound cavity from the external environment, so that impact on sound quality inside the sound cavity that is caused by noise in the external environment is reduced, thereby implementing passive noise reduction.

Abstract: Bispecific antibodies comprising a first targeting moiety which specifically binds to PD-1 and a second targeting moiety which specifically binds to LAG-3, wherein the first targeting moiety comprises a first VHH domain and the second targeting moiety comprises a second VHH domain. Amino acid sequences of the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. Therapeutic compositions comprising the antibodies of the invention are also provided and methods for treating cancers and other diseases with the bispecific antibodies.

Abstract: Disclosed are an unmanned distribution system and method. By means of the system, a temporary storage facility can be arranged at a preset location of a closed distribution area, for example, a corresponding temporary storage facility is arranged near a closed housing estate, community or unit; an external item to be distributed that needs to be distributed is received and temporarily stored by the arranged temporary storage facility; and a robot arranged inside the closed distribution area can obtain the item to be distributed from the temporary storage facility and distribute the item to be distributed within the closed distribution area.