Patents by Inventor Yoshio Kawai

Yoshio Kawai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5478827
    Abstract: This invention relates to heterocyclic derivatives useful for inhibiting the production of Interleukin-1 (IL-1) and tumor necrosis factor (TNF) and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to uses thereof.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: December 26, 1995
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Marusawa, Hitoshi Yamazaki, Yoshito Abe, Hirokazu Tanaka
  • Patent number: 5457003
    Abstract: A resist material comprises a polysiloxane obtained by hydrolysis and condensation with dehydration of one or more alkoxysilanes having an oxirane ring, or of a mixture of the alkoxysilane(s) having an oxirane ring and one or more alkoxysilanes having no oxirane ring, and an acid generator. The resist material may contain one or more of a spectral sensitizer, an organic polymer having a hydroxyl group or an epoxy compound. Resist patterns are formed by coating an organic polymer on a substrate and then the resist material on the film of the organic polymer to form a two layer resist having a bottom layer of the organic polymer and top layer of the resist material, prebaking, imagewise exposing high radiation, postbaking, and developing the resist with alkaline solutions to remove an unexposed portion of the top layer, and dry etching the bottom layer using the relic of the resist material as a mask. the temperature of the post baking is preferably lower than that of the prebaking.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: October 10, 1995
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventors: Akinobu Tanaka, Hiroshi Ban, Jiro Nakamura, Takao Kimura, Yoshio Kawai
  • Patent number: 5356897
    Abstract: This invention relates to heterocyclic derivatives useful for inhibiting the production of Interleukin-1 (IL-1) and tumor necrosis factor (TNF) and the like, which can be represented by the following formula: ##STR1## to a process for their production, to a pharmaceutical composition containing the same and to uses thereof.
    Type: Grant
    Filed: August 17, 1992
    Date of Patent: October 18, 1994
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Marusawa, Hitoshi Yamazaki, Yoshito Abe, Hirokazu Tanaka
  • Patent number: 5356753
    Abstract: A positive resists material for high energy-sensitive positive resists which can be developed in aqueous alkali solution, said material comprising (A) a polyhydroxystyrene resin wherein some hydroxyl groups are substituted by t-butoxycarbonyloxy groups, (B) a solution blocking agent, and (C) an onium salt, and being characterized in that said solution blocking agent contains at least one t-butoxycarbonyloxy group per molecule, said onium salt is bis(p-t-butylphenyl) iodinium trifluormethylsulfonate represented by the following formula (1): ##STR1## and the weight proportions of (A), (B), (C) are given by the relations: 0.07.ltoreq.B-.ltoreq.0.40, 0.005.ltoreq.C.ltoreq.0.15, 0.55.ltoreq.A, A+B+C=1. As the resist has low absorption at the exposure wavelength of a KrF exima laser, a fine pattern having vertical walls is easily formed.
    Type: Grant
    Filed: November 12, 1992
    Date of Patent: October 18, 1994
    Assignees: Shin-Etsu Chemical Co., Ltd., Nippon Telegraph and Telephone Corp.
    Inventors: Motoyuki Yamada, Osamu Watanabe, Akinobu Tanaka, Hiroshi Ban, Yoshio Kawai
  • Patent number: 5280000
    Abstract: The present invention relates to a novel catalyst used for homopolymerization of an olefin of 2 or more carbon atoms or for copolymerization of two or more olefins of 2 or more carbon atoms, as well as to a process for producing an olefin polymer using said catalyst. High molecular olefin polymers can be produced at a high yield, by homopolymerizing an olefin or copolymerizing olefins using a catalyst system consisting of a transition metal compound of the general formula M(R).sub.l (OR').sub.m X.sub.n-(l+m) and an aluminoxane or a catalyst system comprising a transition metal compound of the general formula M(R).sub.l (OR').sub.m X.sub.n-(l+m), an aluminoxane and an organic compound having at least 2 hydroxyl groups.
    Type: Grant
    Filed: August 14, 1991
    Date of Patent: January 18, 1994
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Masahiro Kakugo, Tatsuya Miyatake, Yoshio Kawai, Akinobu Shiga, Kooji Mizunuma
  • Patent number: 5146789
    Abstract: A turbine flowmeter includes an impeller rotatably provided within a flow passage through which a fluid to be measured flows and comprising a rotary shaft which rotates together with the impeller, a pair of bearing part having bearing surfaces for axially supporting the rotary shaft, a holding part for holding the bearing part and provided on the flow passage, an oil accumulating space defined by an end portion of the rotary shaft and bearing surfaces facing respective sides of the end portion, an oil accumulating part provided on the holding part and filled with the lubricating oil to be supplied to the oil accumulating space, an oil supplying part for supplying oil to the oil accumulating space which part comprises a capillary part connected on one end direct to the oil accumulating part and communicated on the other end to the space, wherein the lubricating oil is supplied to the space via the oil supplying part from the oil accumulating part by capillarity introduced in the oil accumulating part and the s
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: September 15, 1992
    Assignee: Tokico Ltd.
    Inventors: Takashi Kato, Yutaka Morita, Takeshi Yamaguchi, Kazuo Tsuge, Kyoji Imamura, Yoshio Kawai, Hiroaki Hasegawa, Hiroyuki Amemori
  • Patent number: 5081126
    Abstract: The invention relates to dithioacetal compounds having 5-lipoxygenase-inhibiting activity, of the formula: ##STR1## wherein R.sup.1 is lower alkyl, di-(lower)alkylamino, aryl, or heterocyclic group which may have one or more substitutents selected from halogen, lower alkyl, lower alkoxy and phenyl,R.sup.2 and R.sup.3 are each lower alkyl, aryl or ar-(lower)alkyl, or R.sup.2 and R.sup.3 are together to form 1,3-dithian ring,R.sup.4 is hydrogen or lower alkoxy, andn is 0 or an integer 1 to 4 and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: January 14, 1992
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 5061718
    Abstract: The invention relates to an anti-inflammatory or antiallergic composition containing a compound of the formula ##STR1## wherein A is ##STR2## R.sup.1 is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl,R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is an integer 1 or 2, andn is an integer 1 to 4, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 30, 1990
    Date of Patent: October 29, 1991
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 5045548
    Abstract: The invention relates to a method of treating asthma comprising administering a compound of the formula: ##STR1## wherein A is ##STR2## R.sup.1 is quinolyl, R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is integer 1 or 2, andn is an integer 1 or 4, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: July 9, 1990
    Date of Patent: September 3, 1991
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 5006111
    Abstract: A medical pump device is constructed so that a pulsation force is applied to the blood in the vicinity of an artery, which is reconstructed after a bypassing operation has been completed, so as to compensate for a deviation of an actual wave form of a blood flow in the vicinity of the reconstructed artery from a normal wave form thereof. The medical pump device is capable of minimizing the possibility of occurrence of a late obturation in an artery which is reconstructed after a reconstruction operation has been completed, and improving a rate of keeping open the reconstructed artery.
    Type: Grant
    Filed: July 18, 1988
    Date of Patent: April 9, 1991
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiyoshi Inokuchi, Kenichiro Okadome, Yoichi Muto, Yoshio Kawai, Tadashi Onuma, Toshiharu Shirakami
  • Patent number: 4990651
    Abstract: Carboxylic acid esters, industrially important compounds, are obtained by reacting carboxylic acid amides and formic acid esters, or carboxylic acid amides, alcohols and carbon monoxide in the presence of metal alcoholate.
    Type: Grant
    Filed: April 12, 1989
    Date of Patent: February 5, 1991
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hideo Ikarashi, Yoshio Kawai, Seiji Nagasawa, Hiroyuki Hirayama
  • Patent number: 4980250
    Abstract: A secondary battery comprising a rechargeable positive electrode, a rechargeable lithium-containing negative electrode, a separator allowing the positive electrode and negative electrode to be separated from each other, and organic electrolyte solution for connecting the positive electrode and negative electrode. The negative electrode includes a complex having a carbon molded article made of carbon fiber or carbon powder having an interfacial distance (d.sub.002) of 3.38 to 3.56 .ANG. as measured by X-ray diffraction analysis using silicon as standard material, wherein lithium have been absorbed into the carbon molded article beforehand. The above value of interfacial distance corresponds to 3.36 to 3.48 .ANG. as measured by X-ray diffraction analysis using no standard material.
    Type: Grant
    Filed: May 5, 1987
    Date of Patent: December 25, 1990
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Yuzuru Takahashi, Yoshio Kawai, Naoto Sakurai
  • Patent number: 4973739
    Abstract: Carboxylic acid esters, industrially important compounds, are efficiently obtained by reacting carboxylic acid amides with formic acid esters in the presence of an inorganic solid acid catalyst.
    Type: Grant
    Filed: April 12, 1989
    Date of Patent: November 27, 1990
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Seiji Nagasawa, Hideo Ikarashi, Yoshio Kawai, Hiroyuki Hirayama
  • Patent number: 4972407
    Abstract: A time-division switching circuit for exchanging a time slot with another time slot in one cycle of time-division multiplexed data where the above one cycle of data comprises a plurality of time-division multiplexed data respectively having a different data formats. The switching circuit comprises: a data buffer memory a successive address generating circuit for outputting successive writing or reading addresses; an address control memory for holding reading or writing addresses; and an address setting control circuit for setting the addresses of the address control memory.
    Type: Grant
    Filed: October 3, 1989
    Date of Patent: November 20, 1990
    Assignee: Fujitsu Limited
    Inventor: Yoshio Kawai
  • Patent number: 4965274
    Abstract: The invention relates to a method of treating arteriosclerosis or pancreatitis comprising administering a compound of the formula: ##STR1## wherein A is ##STR2## R.sup.1 is quinolyl, R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is an integer 1 or 2, andn is an integer 1 to 4, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 27, 1989
    Date of Patent: October 23, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 4963576
    Abstract: The invention relates to dithioacetal compounds having 5-lipoxygenase-inhibiting activity, of the formula: ##STR1## wherein R.sup.1 is lower alkyl, di-(lower)alkylamino, aryl, or heterocyclic group which may have one or more substituents selected from halogen, lower alkyl, lower alkoxy and phenyl,R.sup.2 and R.sup.3 are each lower alkyl, aryl or ar-(lower)alkyl, or R.sup.2 and R.sup.3 are together to form 1,3-dithian ring,R.sup.4 is hydrogen or lower alkoxy, andn is O or an integer 1 to 4 and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 6, 1988
    Date of Patent: October 16, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 4923881
    Abstract: The invention relates to an anti-inflammatory or antiallergic composition containing a compound of the formula ##STR1## wherein A is ##STR2## R.sup.1 is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl,R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is an integer 1 or 2, andn is an integer 1 to 4, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: May 8, 1990
    Assignee: Fujisawa Phatmaceutical Co., Ltd.
    Inventors: Teruo Oku, Yoshio Kawai, Hiroshi Kayakiri, Kazuyoshi Kuratani, Masashi Hashimoto
  • Patent number: 4918996
    Abstract: A turbine flowmeter comprises an impeller which has a rotary shaft rotatable together with the impeller and is provided within a flow passage through which a fluid to be measured flows, a pair of bearing members for axially supporting the rotary shaft, an oil accumulating part provided in a vicinity of the bearing member for holding a lubricating oil therein, and an oil supplying part for supplying the lubricating oil in the oil accumulating part in small quantities to at least one of the bearing members.
    Type: Grant
    Filed: September 30, 1987
    Date of Patent: April 24, 1990
    Assignees: Osaka Gas Co., Ltd., Tokico Ltd.
    Inventors: Takashi Kato, Yutaka Morita, Takeshi Yamaguchi, Kazuo Tsuge, Kyoji Imamura, Yoshio Kawai, Hiroaki Hasegawa, Hiroyuki Amemori
  • Patent number: 4903533
    Abstract: A turbine flowmeter comprises an impeller which has a rotary shaft rotatable together with the impeller and is provided within a flow passage through which a fluid to be measured flows, a pair of bearing members for axially supporting the rotary shaft, an oil accumulating part for holding a lubricating oil therein, and an oil supplying part for supplying the lubricating oil in the oil accomulating part in small quantities to at least one of the bearing members. The oil supplying part comprises a capilary member.
    Type: Grant
    Filed: February 14, 1989
    Date of Patent: February 27, 1990
    Assignees: Osaka Gas Co., Ltd., Tokico Ltd.
    Inventors: Takashi Kato, Yutaka Morita, Takeshi Yamaguchi, Kazuo Tsuge, Kyoji Imamura, Yoshio Kawai, Hiroaki Hasegawa, Hiroyuki Amemori
  • Patent number: 4822335
    Abstract: Apparatus for the treatment of a cancerous lesion part by irradiating a light energy from a light source to the cancerous lesion part having absorbed and accumulated in advance therein a photosensitive substance with an affinity for tumors, in which said light source comprises a first photodiode adapted to excite the photosensitive substance from the ground state thereof to a singlet state of higher energy level and a second photodiode adapted to exite an energy level of the photosensitive substance which has transited from the singlet state to a triplet state to a still higher energy level.
    Type: Grant
    Filed: September 8, 1987
    Date of Patent: April 18, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshio Kawai, Kazue Endo, Makoto Yoshimura