Abstract: A software updating system based on differential updating for reducing the size of updating data and a method of controlling the same are provided. The method includes acquiring differential data between an original image and an updating image for each of a plurality of updating target controllers included in a vehicle. Then low-ranking differential data is acquired in at least one stage between differential data for each of the plurality of updating target controllers and a plurality of differential combinations are generated for all of the plurality of updating target controllers. An optimum combination of the plurality of differential combinations is then determined and updating data is generated depending to the optimum combination.

Abstract: A display device including: a substrate; an active layer, and including channel and conductive regions; a first conductive layer including a driving gate electrode and a scan line in a first direction; a second conductive layer including a storage line; a third conductive layer including a first connecting member above the storage line; an insulating layer between the storage line and the first connecting member; and a data line and a driving voltage line crossing the scan line in a second direction, wherein the first connecting member electrically connects the driving gate electrode and a conductive region, the driving voltage line overlaps the first connecting member, the insulating layer includes first and second sub-insulating layers, and an edge of the second sub-insulating layer substantially overlaps an edge of the first connecting member in a thickness direction of the display device.

Abstract: A display device includes a substrate including a display area, a non-display area, a first additional area connected to the non-display area at a first boundary, and a second additional area connected to the first additional area at a second boundary, pixels on the display area, an encapsulation film on the pixels, electrodes on the encapsulation film, pads on the second additional area, sensing wires connecting the electrodes and the pads, a first sensing insulating film on the encapsulation film, and a second sensing insulating film on the first sensing insulating film. The substrate includes a curved first side in the first additional area and the first additional area decreases in width from the first boundary to the second boundary, and a boundary of the first sensing insulating film is closer to the first side than a boundary of the second sensing insulating film is to the first side.

Abstract: A display device includes a substrate having an active area, a visible region located on the active area, and a non-visible region farther from the active area in a first direction than the visible region is; a first conductive layer disposed on the substrate; a first insulating layer disposed on the first conductive layer; a second conductive layer disposed on the first insulating layer; a first via layer disposed on the second conductive layer; a second insulating layer disposed on the first via layer; and a third conductive layer disposed on the second insulating layer and including touch signal lines. The visible region includes a line area where the second conductive layer is disposed, and a line-free area where the second conductive layer is not disposed. The third conductive layer includes a dummy pattern disposed in the line-free area and has a width greater than the touch signal lines.

Abstract: Provided are an anti-B7-H3 antibody binding specifically to B7-H3 and a use thereof and, more particularly, are an anti-B7-H3 antibody or an antigen binding fragment thereof, a nucleic acid encoding the same, a vector carrying the nucleic acid, a cell transformed with the vector, a method for preparing the same, an antibody-drug conjugate or a multi-specific antibody comprising the same, and a pharmaceutical composition for preventing or treating cancer, autoimmune disease, or inflammatory disease, or a diagnostic composition, each composition comprising the same. The anti-B7-H3 antibody or antigen binding fragment thereof can bind to human and non-human B7-H3 at high affinity and can be endocytosized after binding thereto. Thus, the anti-B7-H3 antibody or antigen binding fragment thereof, or the antibody-drug conjugate or the multi-specific antibody comprising the same can be advantageously used for preventing, treating, or diagnosing cancer or tumor, autoimmune disease, or inflammatory disease.

Abstract: The present invention relates to new antibody-drug conjugates (ADCs) targeting DLK1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically, uses for such ADCs in producing drugs for treatment and/or prevention of proliferative and/or angiogenetic diseases, for example, cancer. More particularly, the present invention relates to an antibody-drug conjugate comprising an antibody binding with DLK1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.

Abstract: The present invention relates to a film wrapping machine for a product packing device using a stretch film, including a frame having vertical bars extending upward and spaced apart from each other, a film clamping unit including a pair of suction pads which are moved in a direction of being spaced apart from each other in a state of adsorbing the stretch film so that a front end portion of the stretch film supplied from a film supply device is opened, and a plurality of clamps configured to grip the front end portion of the stretch film opened by the suction pads, receive the stretch film whose upper end is cut and bonded by the film supply device in a wrinkled state, and process the stretch film to be covered on a product in a process of lowering the vertical bars, and a controller which controls operation of the film clamping unit and the film supply device.

Abstract: New anti-VSIG4 (V-set Ig domain-containing 4) antibodies or an antigen-binding fragments are disclosed. Uses of these antibodies, including methods of treatment, are also provided.

Abstract: A display device includes: a display unit including a flat part and a curved part which is formed to be bent from sides of the flat part; a sensing unit on the display unit to overlap with the flat part and the curved part; and a passivation layer on the sensing unit, wherein the passivation layer overlaps with the flat part and the passivation layer does not overlap the curved part.

Abstract: Disclosed herein is an organic light emitting diode display, including a substrate, a first thin film transistor including a first active pattern on the substrate and a first gate electrode on the first active pattern, a data wire on the first gate electrode, a first interlayer insulating layer between the first gate electrode and the data wire, a second interlayer insulating layer positioned the first interlayer insulating layer and the data wire, and an organic light emitting diode positioned on the data wire and connected to the first active pattern.

Abstract: The present invention relates to a chromatography strip for diagnosing pregnancy having multiple test lines, a pregnancy diagnosis kit having the chromatography strip, and a method for diagnosing pregnancy using the same. The present invention overcomes the problem of false negatives due to hCG variants such that pregnancy can be determined more accurately and conveniently by the naked eye. Furthermore, there is an effect of improving the concentration measurement range of hCG or a variant thereof by using a chromatography strip for diagnosing pregnancy which is constituted by multiple test lines and control lines.

Abstract: The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.

Abstract: A bispecific antibody according to an embodiment of the present disclosure specifically binds to IL-17A and TNF-?. The bispecific antibody according to the present invention or an antigen binding fragment thereof exhibits high specificity for IL-17A and TNF-? and more favorable neutralization property compared to monospecific antibody of a prior art, and, by quickly suppressing inflammation and an immune response by inhibiting simultaneously IL-17 and TNF-?, it has an advantage of improving the treatment effect with lower dose.

Abstract: A display device includes a substrate including a display area, a non-display area, a first additional area connected to the non-display area at a first boundary, and a second additional area connected to the first additional area at a second boundary, pixels on the display area, an encapsulation film on the pixels, electrodes on the encapsulation film, pads on the second additional area, sensing wires connecting the electrodes and the pads, a first sensing insulating film on the encapsulation film, and a second sensing insulating film on the first sensing insulating film. The substrate includes a curved first side in the first additional area and the first additional area decreases in width from the first boundary to the second boundary, and a boundary of the first sensing insulating film is closer to the first side than a boundary of the second sensing insulating film is to the first side.

Abstract: The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer containing the same. The novel antibody binding to PD-1 or an antigen-binding fragment thereof can bind to PD-1 and inhibit the activity of PD-1, thus being useful for the development of immunotherapeutic agents for various diseases associated with PD-1.

Abstract: Disclosed herein is an organic light emitting diode display, including a substrate, a first thin film transistor including a first active pattern on the substrate and a first gate electrode on the first active pattern, a data wire on the first gate electrode, a first interlayer insulating layer between the first gate electrode and the data wire, a second interlayer insulating layer positioned the first interlayer insulating layer and the data wire, and an organic light emitting diode positioned on the data wire and connected to the first active pattern.

Abstract: A display device includes a substrate having an active area, a visible region located on the active area, and a non-visible region farther from the active area in a first direction than the visible region is; a first conductive layer disposed on the substrate; a first insulating layer disposed on the first conductive layer; a second conductive layer disposed on the first insulating layer; a first via layer disposed on the second conductive layer; a second insulating layer disposed on the first via layer; and a third conductive layer disposed on the second insulating layer and including touch signal lines. The visible region includes a line area where the second conductive layer is disposed, and a line-free area where the second conductive layer is not disposed. The third conductive layer includes a dummy pattern disposed in the line-free area and has a width greater than the touch signal lines.

Abstract: A display device includes a substrate including a display area, a non-display area, a first additional area connected to the non-display area at a first boundary, and a second additional area connected to the first additional area at a second boundary, pixels on the display area, an encapsulation film on the pixels, electrodes on the encapsulation film, pads on the second additional area, sensing wires connecting the electrodes and the pads, a first sensing insulating film on the encapsulation film, and a second sensing insulating film on the first sensing insulating film. The substrate includes a curved first side in the first additional area and the first additional area decreases in width from the first boundary to the second boundary, and a boundary of the first sensing insulating film is closer to the first side than a boundary of the second sensing insulating film is to the first side.

Abstract: A software updating system based on differential updating for reducing the size of updating data and a method of controlling the same are provided. The method includes acquiring differential data between an original image and an updating image for each of a plurality of updating target controllers included in a vehicle. Then low-ranking differential data is acquired in at least one stage between differential data for each of the plurality of updating target controllers and a plurality of differential combinations are generated for all of the plurality of updating target controllers. An optimum combination of the plurality of differential combinations is then determined and updating data is generated depending to the optimum combination.