Abstract: The present disclosure relates to compositions and methods of enhancing expansion of a population of cells targeting a solid tumor and/or enhancing treatment on the solid tumor using the population of cells. For example, the method comprises administering an effective amount of a composition comprising a first population of cells targeting a WBC antigen and a second population of cells targeting the solid tumor to a subject having the solid tumor; and allowing the second population of cells to expand, wherein there are at least as many or more of the second population of cells targeting the solid tumor than the first population of cells targeting the WBC antigen.

Abstract: Provided are a method and apparatus for processing a video bitstream, a network device and a readable storage medium. The method includes: parsing a bitstream to be extracted, and acquiring parameter information about an extractable sub-bitstream from a data unit of the bitstream to be extracted; determining a picture type parameter value of a random access picture in the sub-bitstream according to the parameter information; and configuring, in a process of extracting the sub-bitstream from the bitstream to be extracted, a picture type parameter value in a data unit of the sub-bitstream according to the picture type parameter value of the random access picture.

Abstract: Provided are a media information processing method, apparatus and system. The method comprises: generating media indication information according to a media state and/or a media state change, wherein the media indication information at least comprises one of the following: a media identifier, a media state type, a media state change type, a media state description, and a media state change description; and sending or storing the media indication information. By means of the present disclosure, the problem in the relevant art that the covered content in media information is incomplete during a media interaction is solved, thereby achieving the effect of improving the media information integrity and expandability.

Abstract: Disclosed are an encoding processing method and device, a decoding processing method and device, an encoder and a decoder. The encoding processing method includes: determining a filtering process to be applied to a pixel in a prediction reference block for an encoding block; filtering the pixel in the prediction reference block according to the filtering process; constructing a pixel prediction value for the encoding block according to a filtered pixel sampling value in the prediction reference block; and encoding the encoding block according to the pixel prediction value.

Abstract: An image coding method and apparatus and an image decoding method and apparatus are provided by the present invention. The image coding method includes: implementing matching coding for pixels of an input video image to obtain one or more matching relationship parameters, herein the matching relationship parameters are parameters used in a process of constructing predicted values and/or reconstructed values of the pixels in the image; mapping the matching relationship parameters to obtain mapped values of the matching relationship parameters; and performing entropy coding on the mapped values of the matching relationship parameters. The present invention addresses the problem existing in the conventional art which is caused by the direct implementation of entropy coding for matching relationship parameters and achieves a good data compression effect through entropy coding.

Abstract: Provided is a bitstream processing method, including: acquiring auxiliary information in a bitstream, where the auxiliary information includes at least one of bitstream information for transcoding or bitstream information for supporting transcoding; and transcoding the bitstream by using the auxiliary information and generating a transcoded bitstream. Further provided are a bitstream processing device and a storage medium.

Abstract: The present disclosure relates to compositions and methods for reducing immune tolerance associated with CAR T cell therapy. Embodiments of the present disclosure include isolated nucleic acid sequence comprising a nucleic acid sequence that encodes modified programmed cell death protein 1 (PD-1) and a nucleic acid sequence that encodes chimeric antigen receptor (CAR).

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: An image coding method and apparatus and an image decoding method and apparatus are provided by the present document. The image coding method includes: implementing matching coding for pixels of an input video image to obtain one or more matching relationship parameters, herein the matching relationship parameters are parameters used in a process of constructing predicted values and/or reconstructed values of the pixels in the image; mapping the matching relationship parameters to obtain mapped values of the matching relationship parameters; and performing entropy coding on the mapped values of the matching relationship parameters. The present document addresses the problem existing in the conventional art which is caused by the direct implementation of entropy coding for matching relationship parameters and achieves a good data compression effect through entropy coding.

Abstract: A method and apparatus for decoding a video bitstream, a method and apparatus for generating a video bitstream, storage medium and an electronic device are provided. The method for decoding the video bitstream includes that: a first parameter of a reference position of a slice in a video picture is acquired; a second parameter of the slice is acquired, the second parameter being used for determining a starting position of the slice in the video picture; and a starting position coordinate parameter of the slice in the video picture is calculated according to the first parameter and the second parameter.

Abstract: An image coding method and apparatus, and an image decoding method and apparatus are provided. In the coding method, a scanning manner parameter of a coding block is determined, and the scanning manner parameter may include at least one of: a region indication parameter used for determining a scanning region of the coding block and a scanning indication parameter used for determining a scanning order of pixels in a scanning region of the coding block; predicted values of part or all of pixels in the coding block are determined according to the scanning manner parameter; and the coding block is coded according to the predicted values, and a coding result is written into a bitstream.

Abstract: Provided is an encoding and decoding method and device for data compression. The encoding method includes: adaptively selecting a constrained string mode from a plurality of preset constrained string modes; and performing, according to the selected constrained string mode, string-matching encoding on a coding block to obtain information of a constrained string encoded in the selected constrained string mode and to obtain a bitstream of a syntax element of the constrained string encoded in the selected constrained string mode.

Abstract: Several embodiments of the present invention are described for a media data processing method, apparatus and system. An example method comprises: obtaining an optical signal of a sampling point by a collection device at the source end in an acquisition of media data; according to an opto-electronic transfer control parameter, performing opto-electronic transfer for the optical signal of the sampling point to obtain a transferred electrical signal, wherein the opto-electronic transfer control parameter is determined on the basis of an optical signal intensity of the optical signal of the sampling point; and encoding the electrical signal and opto-electronic transfer control parameter to obtain a bitstream. According to the embodiment of the present invention, the problem of the lower accuracy in the media data processing is solved, thereby obtaining the effect of improving the accuracy in the media data processing.

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: An image coding method and apparatus, and an image decoding method and apparatus are provided. In the coding method, a scanning manner parameter of a coding block is determined, and the scanning manner parameter may include at least one of: a region indication parameter used for determining a scanning region of the coding block and a scanning indication parameter used for determining a scanning order of pixels in a scanning region of the coding block; predicted values of part or all of pixels in the coding block are determined according to the scanning manner parameter; and the coding block is coded according to the predicted values, and a coding result is written into a bitstream.

Abstract: The present disclosure provides a method and device for image coding and a method and device for image decoding, and the method includes: a representative pixel set of a coding block is constructed, and information for constructing the representative pixel set is determined; predicted values of pixel samples in the coding block are constructed, a generation manner for the predicted values including: constructing the predicted values of the pixel samples according to reconstructed pixel samples in an image region outside the coding block and pixel values of the representative pixel set; and the information for constructing the representative pixel set and information for constructing the predicted values are coded and written into a video bitstream.

Abstract: Provided are picture encoding and decoding methods and apparatuses, and a picture encoding and decoding system. The picture encoding method includes: determining an adjustment factor according to pixel sampling values of a video picture; converting the video picture according to the adjustment factor, and encoding the converted video picture; and writing the adjustment factor into a bitstream obtained by encoding the converted video picture.

Abstract: The present disclosure provides a method and device for image coding and a method and device for image decoding, and the method includes: a representative pixel set of a coding block is constructed, and information for constructing the representative pixel set is determined; predicted values of pixel samples in the coding block are constructed, a generation manner for the predicted values including: constructing the predicted values of the pixel samples according to reconstructed pixel samples in an image region outside the coding block and pixel values of the representative pixel set; and the information for constructing the representative pixel set and information for constructing the predicted values are coded and written into a video bitstream.

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: The present disclosure relates to compositions and methods for reducing immune tolerance associated with CAR T cell therapy. Embodiments of the present disclosure include isolated nucleic acid sequence comprising a nucleic acid sequence that encodes modified programmed cell death protein 1 (PD-1) and a nucleic acid sequence that encodes chimeric antigen receptor (CAR).