Abstract: Embodiments of the present invention may track a user's interaction trajectory associated with a problem occurred on a website. According to an embodiment of the present invention, a first symbol of a first definition associated with a first object file is obtained. Then, in response to the first symbol matching a second symbol of a second definition associated with a second object file, the first object file is optimized based on a first segment associated with the first definition in the first object file and an optimization to the second object file is skipped. Next, an executable file is generated based on the optimized first object file and the second object file.

Abstract: Embodiments described herein relate to compositions including genetically modified CAR cells and uses thereof for treating cancer. Some embodiments of the present disclosure relate to compositions and methods for T cell response enhancement and/or CAR cell preparation. For example, a method may include obtaining cells comprising a CAR and culturing the cells in the presence of an agent that is recognized by the extracellular domain of the CAR.

Abstract: Embodiments of the present invention may track a user's interaction trajectory associated with a problem occurred on a website. According to an embodiment of the present invention, a first symbol of a first definition associated with a first object file is obtained. Then, in response to the first symbol matching a second symbol of a second definition associated with a second object file, the first object file is optimized based on a first segment associated with the first definition in the first object file and an optimization to the second object file is skipped. Next, an executable file is generated based on the optimized first object file and the second object file.

Abstract: The present disclosure relates to a genetically modified cell (e.g., stem cells) containing a complete or partial gene deletion of one or more genes of a blood group antigen (BGA) biosynthesis or transportation pathway. The systems and methods provided herein facilitate the generation of blood substitutes (e.g., blood cells).

Abstract: An image coding method and apparatus and an image decoding method and apparatus are provided by the present document. The image coding method includes: implementing matching coding for pixels of an input video image to obtain one or more matching relationship parameters, herein the matching relationship parameters are parameters used in a process of constructing predicted values and/or reconstructed values of the pixels in the image; mapping the matching relationship parameters to obtain mapped values of the matching relationship parameters; and performing entropy coding on the mapped values of the matching relationship parameters. The present document addresses the problem existing in the conventional art which is caused by the direct implementation of entropy coding for matching relationship parameters and achieves a good data compression effect through entropy coding.

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: The present disclosure relates to compositions, methods, and systems for selectively activating and/or expanding T cells for use in therapy. For example, the method may include contacting a population of T cells with an agent capable of binding an extracellular domain of a chimeric antigen receptor (CAR) that is expressed on the surface of the population of T cells.

Abstract: Disclosed are an image encoding and decoding method, image processing device, and computer storage medium, comprising: entropy-encoding a plurality of replication parameters of a current encoding block according to their order after adjustment, to generate a video code stream comprising information of the plurality of replication parameters; said plurality of replication parameters comprising one or more types of replication parameter components. Parsing the video code stream, comprising the information of the plurality of replication parameters, of a decoding block; entropy-decoding said plurality of replication parameters to obtain binary code of said plurality of replication parameters; adjusting said binary code to obtain the values of said plurality of replication parameters; said plurality of replication parameters comprising one or more types of replication parameter components.

Abstract: Disclosed are an image coding and decoding methods, an image processing device, and a computer storage medium. The image coding method comprises: obtaining a dynamic range of a copy parameter of a current coding sampling value segment according to a size of a reference area; and coding the copy parameter according to the dynamic range to generate a video bitstream containing information about the size of the reference area and information about the copy parameter. The decoding method comprises: parsing a video bitstream to obtain a dynamic range of a copy parameter of a decoding sampling value segment; and decoding the copy parameter according to the dynamic range.

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: Disclosed are a bitstream alignment and synchronous processing method, transmitting terminal, receiving terminal and communication system. The method includes: configuring, when multiple bitstreams are required to be aligned, by a transmitting terminal, alignment auxiliary information in the multiple bitstreams so as to store the same or transmit the same to a receiving terminal; and acquiring, by the receiving terminal, the multiple bitstreams, and synchronizing each of the bitstreams of a different standard according to the alignment auxiliary information carried in each of the bitstreams.

Abstract: Disclosed are an image encoding and decoding method, image processing device, and computer storage medium, comprising: when using one of a palette and a pixel-string encoding replication means to replicate the encoding of a currently encoded block, generating a new palette color according to the pixels of said currently encoded block; according to said new palette color and/or palette color candidate set shared by the palette and the pixel-string encoding replication means, generating the palette of said current encoded block; using said palette to replicate the encoding of the palette and the pixel string, and generate a video code stream comprising the replication means and replication parameters.

Abstract: Embodiments herein relate to humanized CD19 antibodies and disease treatment using the antibodies. For example, a subject having a CD19 positive tumor may be administered a therapeutically effective amount of the humanized antibody.

Abstract: A genetically modified cell (e.g., stem cell) containing a complete or partial gene deletion of one or more genes of a blood group antigen (BGA) biosynthesis or transportation pathway is provided. The systems and methods provided herein facilitate the generation of blood substitutes (e.g., blood cells).

Abstract: The present disclosure relates to a genetically modified cell (e.g., stem cells) containing a complete or partial gene deletion of one or more genes of a blood group antigen (BGA) biosynthesis or transportation pathway. The systems and methods provided herein facilitate the generation of blood substitutes (e.g., blood cells).

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: The present disclosure provides a method and device for image coding and a method and device for image decoding, and the method includes: a representative pixel set of a coding block is constructed, and information for constructing the representative pixel set is determined; predicted values of pixel samples in the coding block are constructed, a generation manner for the predicted values including: constructing the predicted values of the pixel samples according to reconstructed pixel samples in an image region outside the coding block and pixel values of the representative pixel set; and the information for constructing the representative pixel set and information for constructing the predicted values are coded and written into a video bitstream.

Abstract: An image coding method and apparatus, and an image decoding method and apparatus are provided. In the coding method, a scanning manner parameter of a coding block is determined, and the scanning manner parameter may include at least one of: a region indication parameter used for determining a scanning region of the coding block and a scanning indication parameter used for determining a scanning order of pixels in a scanning region of the coding block; predicted values of part or all of pixels in the coding block are determined according to the scanning manner parameter; and the coding block is coded according to the predicted values, and a coding result is written into a bitstream.

Abstract: The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.

Abstract: Embodiments of the present invention may track a user's interaction trajectory associated with a problem occurred on a website. According to an embodiment of the present invention, a first symbol of a first definition associated with a first object file is obtained. Then, in response to the first symbol matching a second symbol of a second definition associated with a second object file, the first object file is optimized based on a first segment associated with the first definition in the first object file and an optimization to the second object file is skipped. Next, an executable file is generated based on the optimized first object file and the second object file.