Patents by Inventor Zhijian Lu

Zhijian Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090137548
    Abstract: Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. The compounds have 3 cyclic groups connected by single bonds, as for example triphenyl, which are attached directly to the ring of formula I or attached at the position B.
    Type: Application
    Filed: December 29, 2006
    Publication date: May 28, 2009
    Inventors: Amjad Ali, Zhijian Lu, Peter J. Sinclair, Yi-Heng Chen, Cameron J. Smith, Hong Li
  • Publication number: 20090124689
    Abstract: Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group, as shown in Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis:
    Type: Application
    Filed: October 13, 2006
    Publication date: May 14, 2009
    Inventors: Yi-Heng Chen, Zhijian Lu, Peter J. Sinclair
  • Patent number: 7526075
    Abstract: A method for realizing charging includes setting up mapping relation between service attribute and charging rule acquiring service attribute of the to-be-charged service when it is demanded to charge the to-be-charged service acquiring charging rule of the to-be-charged service according to service attribute of the to-be-charged service, and charging the to-be-charged service according to the acquired charging rule. Also disclosed is a charging system having an acquiring charging rule module and charging processing module. When it is demanded to develop new services or modify charging rules of original services, it can be fulfilled by modifying the service information provided for charging processing module accordingly, thus charging requirements of various services can be satisfied. Charging processing module of charging system is independent of services, so that cost of charging system is reduced, and stability, reliability and versatility of charging system are improved.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: April 28, 2009
    Assignee: Huawei Technologies Co., Ltd
    Inventors: Xiaozheng Guo, Zhijian Lu, Xin Zhang, Qingchen Chu, Youkun Chen
  • Patent number: 7514237
    Abstract: The invention relates to systems and methods for producing proteins of interest. The invention employs genetically-engineered animal or plant cells that have modified protein folding or processing capacities. In one aspect, the invention features genetically-engineered cells comprising one or more recombinant expression cassettes which encode (1) a protein of interest and (2) a polypeptide that is functional in the unfolded protein response (UPR) pathway of the cells. Co-expression of the polypeptide significantly increases the yield of the protein of interest in the genetically-engineered cells. In one example, the genetically-engineered cells are animal cells, and the co-expressed polypeptide is a component or modulator of an XBP1- or ATF6-mediated UPR pathway.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: April 7, 2009
    Assignee: Wyeth
    Inventors: Yijie Gao, Nicole M. Piche, Mei Geng, Stephen H. Herrmann, Xiaotian Zhong, Ronald Kriz, Zhijian Lu
  • Publication number: 20090085120
    Abstract: Fabrication of interconnects in integrated circuits (ICs) use low-k dielectric materials, nitrogen containing dielectric materials, copper metal lines, dual damascene processing and amplified photoresists to build features smaller than 100 nm. Regions of an IC with low via density are subject to nitrogen diffusion from nitrogen containing dielectric materials into low-k dielectric material, and subsequent interference with forming patterns in amplified photoresists, a phenomenon known as resist poisoning, which results in defective interconnects. Attempts to solve this problem cause lower IC circuit performance or higher fabrication process cost and complexity. This invention comprises a dummy via and a method of placing dummy vias in a manner that reduces resist poisoning without impairing circuit performance or increasing fabrication process cost or complexity.
    Type: Application
    Filed: September 28, 2007
    Publication date: April 2, 2009
    Applicant: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Zhijian Lu, Tae S. Kim
  • Publication number: 20090075979
    Abstract: Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B or R2 is a phenyl group which has an ortho amine or aminomethyl substituent which is further substituted, and the other of B or R2 is also a cyclic group.
    Type: Application
    Filed: December 29, 2006
    Publication date: March 19, 2009
    Inventors: Amjad Ali, Zhijian Lu, Peter J. Sinclair, Gayle E. Taylor, Christopher F. Thompson, Cameron J. Smith, Adrian A. Dowst, Yi-Heng Chen
  • Publication number: 20090042892
    Abstract: Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B is a cyclic group other than phenyl, and B has a cyclic substituent at a position that is ortho to the position at which B is connected to the remainder of the structure of Formula (I). The 5-membered ring of Formula (I) has a second cyclic substituent in addition to B.
    Type: Application
    Filed: December 29, 2006
    Publication date: February 12, 2009
    Inventors: Amjad Ali, Zhijian Lu, Peter J. Sinclair, Yi-Heng Chen, Cameron J. Smith, Hong Li, Christopher F. Thompson
  • Patent number: 7425502
    Abstract: The present invention provides a method for manufacturing an interconnect and a method for manufacturing an integrated circuit including the interconnect. The method of manufacturing an interconnect, among other steps, includes forming a via (160) in a substrate (130) and then forming a base getter material (210) in the via (160). The method further includes forming a photoresist layer (410) over the base getter material (210), the photoresist layer (410) having an opening (420) therein positioned over the via (160), and etching a trench (510) into the substrate (130) using the opening (420) in the photoresist layer (410).
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: September 16, 2008
    Assignee: Texas Instruments Incorporated
    Inventors: Zhijian Lu, Thomas M. Wolf, Scott W. Jessen
  • Publication number: 20080119476
    Abstract: Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: In the compounds of Formula I, B or R2 is a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5-membered ring has an aromatic, heterocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a —CH2—.
    Type: Application
    Filed: July 1, 2005
    Publication date: May 22, 2008
    Inventors: Amjad Ali, Joann M. Napolitano, Qiaolin Deng, Zhijian Lu, Peter J. Sinclair, Gayle E. Taylor, Christopher F. Thompson, Nazia Quraishi, Cameron J. Smith, Julianne A. Hunt, Adrian A. Dowst, Yi-Heng Chen, Hong Li
  • Publication number: 20080065571
    Abstract: A general charging method includes establishing a charging strategy and performing the charging according to the charging strategy. The charging strategy includes at least one priority each of which includes at least one time period and each of the time periods is provided at least one rate segment in each of which there is at least one rate. Performing the charging includes: matching with a corresponding charging strategy upon the time a subscriber uses a service and/or the subscriber's current resource, and determining a charging mode; searching for a corresponding priority; performing the charging according to the charging mode. With such a structure of general charging strategy, the method can satisfy various charging demands and provide generality and adequate expansibility. Also, the method enables subscribers to configure different charging methods as necessary.
    Type: Application
    Filed: November 8, 2007
    Publication date: March 13, 2008
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Zhijian LU, Xin ZHANG, XiaoZheng GUO, Qingchen CHU, Youkun CHEN
  • Publication number: 20080051340
    Abstract: Members of the TGF-? superfamily and peptide fragments based on member proteins are employed to purify solutions containing member proteins or as therapeutics.
    Type: Application
    Filed: June 1, 2007
    Publication date: February 28, 2008
    Applicant: Wyeth
    Inventors: Zhijian Lu, Wei Liu, Jimin Zhang, Paul Yaworsky, Stephane Olland, Christopher Brown, Emily Sheng-ming Shen
  • Publication number: 20080020580
    Abstract: The present invention provides a method for manufacturing an interconnect and a method for manufacturing an integrated circuit including the interconnect. The method of manufacturing an interconnect, among other steps, includes forming a via (160) in a substrate (130) and then forming a base getter material (210) in the via (160). The method further includes forming a photoresist layer (410) over the base getter material (210), the photoresist layer (410) having an opening (420) therein positioned over the via (160), and etching a trench (510) into the substrate (130) using the opening (420) in the photoresist layer (410).
    Type: Application
    Filed: July 25, 2007
    Publication date: January 24, 2008
    Applicant: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Zhijian Lu, Thomas Wolf, Scott Jessen
  • Publication number: 20080020291
    Abstract: A large mask with random apertures may be formed by forming a smaller mask (also called a cell mask) with a random pattern of transmissive apertures which is then repeatedly replicated to create the large mask. The random pattern may be created by perturbing the aperture locations by a small amount or the apertures may be randomly placed within the cell mask provided certain criteria are met. Alternatively, a large mask with a random pattern of transmissive apertures may be formed without using a cell mask. This large mask may be used to fabricate diffusers and other devices that do not suffer from the interference, diffraction and other optical effects common in devices having structures that are non-randomly patterned.
    Type: Application
    Filed: July 20, 2006
    Publication date: January 24, 2008
    Inventor: Zhijian Lu
  • Patent number: 7313230
    Abstract: The present invention provides a general charging method applicable to a charging system in the communication field, comprising steps of establishing a charging strategy and performing the charging based upon the charging strategy. The charging strategy comprises a plurality of priorities each of which comprises a plurality of periods of time, and each of the periods of time corresponds to a type of rate segmentation and is provided a plurality of rate segments in each of which there are a plurality of rates. The step of performing the charging comprises steps of: searching for the highest priority in the charging strategy; searching for a corresponding period of time in the priority based upon the time a subscriber uses a service, and if found, performing the charging based upon the rate segments in the period of time; when the charging has been completed or the priorities have been searched through, and if there is any usage quantity that can't be charged, recording it and terminating the charging.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: December 25, 2007
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Zhijian Lu, Xin Zhang, Xiaozheng Guo, Qingchen Chu, Youkun Chen
  • Publication number: 20070275215
    Abstract: Diffusers including of a plurality of protruded structures with each structure containing multiple rugged facets are disclosed. The diffuser may be fabricated by coating a mixture of materials on a carrier film, the mixture of materials including at least a first material that polymerizes upon irradiation and at least a second material that is incompatible with the first material in polymerized form, then selectively irradiating the mixture of materials to polymerize a portion of the mixture of materials to form polymerized structures, and finally removing that part of the mixture of materials not forming part of the structures. A transparent material may be coated over the structures.
    Type: Application
    Filed: May 24, 2006
    Publication date: November 29, 2007
    Inventor: Zhijian Lu
  • Publication number: 20070274481
    Abstract: A method for realizing charging includes setting up mapping relation between service attribute and charging rule, acquiring service attribute of the to-be-charged service when it is demanded to charge the to-be-charged service, acquiring charging rule of the to-be-charged service according to service attribute of the to-be-charged service, and charging the to-be-charged service according to the acquired charging rule. Also disclosed is a charging system having an acquiring charging rule module and charging processing module. When it is demanded to develop new services or modify charging rules of original services, it can be fulfilled by modifying the service information provided for charging processing module accordingly, thus charging requirements of various services can be satisfied. Charging processing module of charging system is independent of services, so that cost of charging system is reduced, and stability, reliability and versatility of charging system are improved.
    Type: Application
    Filed: July 30, 2004
    Publication date: November 29, 2007
    Applicant: Huawei Technologies Co., Ltd.
    Inventors: Xiaozheng Guo, Zhijian Lu, Xin Zhang, Qingchen Chu, Youkun Chen
  • Publication number: 20070225365
    Abstract: Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.
    Type: Application
    Filed: April 8, 2005
    Publication date: September 27, 2007
    Applicant: MERCK & CO., INC.
    Inventors: Amjad Ali, Joann Bohn, Qiaolin Deng, Zhijian Lu, Peter Sinclair, Gayle Taylor, Christopher Thompson, Nazia Quraishi
  • Patent number: 7262129
    Abstract: The present invention provides a method for manufacturing an interconnect and a method for manufacturing an integrated circuit including the interconnect. The method of manufacturing an interconnect, among other steps, includes forming a via (160) in a substrate (130) and then forming a base getter material (210) in the via (160). The method further includes forming a photoresist layer (410) over the base getter material (210), the photoresist layer (410) having an opening (420) therein positioned over the via (160), and etching a trench (510) into the substrate (130) using the opening (420) in the photoresist layer (410).
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: August 28, 2007
    Assignee: Texas Instruments Incorporated
    Inventors: Zhijian Lu, Thomas M. Wolf, Scott W. Jessen
  • Publication number: 20070041211
    Abstract: A structure including an integrally formed diffuser may be formed by depositing a first layer including a first polymerizable material and another material, and depositing a second layer including a second polymerizable material adjacent the first layer. The first and second layers are simultaneously irradiated with light that causes the first polymerizable material and the second polymerizable material to polymerize. There is not an optical boundary between the first and second layers since the first and second materials are polymerized together.
    Type: Application
    Filed: May 12, 2006
    Publication date: February 22, 2007
    Inventors: Zhijian Lu, John Magno, Gene Koch
  • Publication number: 20060253292
    Abstract: The present invention provides a general charging method applicable to a charging system in the communication field, comprising steps of establishing a charging strategy and performing the charging based upon the charging strategy. The charging strategy comprises a plurality of priorities each of which comprises a plurality of periods of time, and each of the periods of time corresponds to a type of rate segmentation and is provided a plurality of rate segments in each of which there are a plurality of rates. The step of performing the charging comprises steps of: searching for the highest priority in the charging strategy; searching for a corresponding period of time in the priority based upon the time a subscriber uses a service, and if found, performing the charging based upon the rate segments in the period of time; when the charging has been completed or the priorities have been searched through, and if there is any usage quantity that can't be charged, recording it and terminating the charging.
    Type: Application
    Filed: December 31, 2003
    Publication date: November 9, 2006
    Applicant: HUAWEI TECHNOLOGIES CO., LTD
    Inventors: Zhijian Lu, Xin Zhang, Xiaozheng Guo, Qingchen Chu, Youkun Chen