Patents by Inventor Zhonghua Zhang

Zhonghua Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100063038
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 1, 2006
    Publication date: March 11, 2010
    Inventors: Julie Dixon, Barton Phillips, Furahi Achebe, Harold Kluender, Jason Newcom, Kyle Parcella, Stephen J. O'Connor, Steven Magnuson, Zhenqui Hong, Zhonghua Zhang, Zheng Liu, Uday Khire, Lei Wang, Martin Michels, Brent Chandler
  • Publication number: 20090298854
    Abstract: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
    Type: Application
    Filed: July 23, 2009
    Publication date: December 3, 2009
    Inventors: Xin Ma, Louis-David Cantin, Soongyu Choi, Roger Clark, Martin Hentemann, Joachim Rudolph, Rico Lavoie, Zhonghua Zhang
  • Publication number: 20090281079
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: November 30, 2006
    Publication date: November 12, 2009
    Applicant: BAYER HEALTHCARE LLV
    Inventors: Julie Dixon, Steven Magnuson, Barton Phillips, Yamin Wang, Tandy Li, Kyle Parcella, Jason Newcom, Harold Kluender, Zhenqiu Hong, Brent Chandler, Zhonghua Zhang, Kristen Allegue, Zheng Liu
  • Patent number: 7592361
    Abstract: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: September 22, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Xin Ma, Louis-David Cantin, Soongyu Choi, Roger Clark, Martin Hentemann, Joachim Rudolph, Rico Lavoie, Zhonghua Zhang
  • Publication number: 20060264486
    Abstract: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 23, 2006
    Inventors: Xin Ma, Louis-David Cantin, Soongyu Choi, Roger Clark, Martin Hentemann, Joachim Rudolph, Rico Lavoie, Zhonghua Zhang
  • Patent number: 7071207
    Abstract: This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: July 4, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger A. Smith, Stephen J. O'Connor, Wai C. Wong, Soongyu Choi, Harold C. Kluender, Jianmei Fan, Zhonghua Zhang, Rico C. Lavoie, Brent L. Podlogar
  • Publication number: 20060122215
    Abstract: This invention relates to 1,5,6,7-tetrahydropynolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: January 18, 2006
    Publication date: June 8, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen O'Connor, Wai Wong, Soongyu Choi, Harold Kluender, Jianmei Fan, Zhonghua Zhang, Rico Lavoie, Brent Podlogar
  • Publication number: 20050119489
    Abstract: Disclosed are 4-sulfide/sulfoxide/sulfonyl-1H-pyrazolyl derivative compounds of formulas (I) or (II): wherein the variables n, R, R1, R2, R3, R3?, R4, R4?, R5 and R6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT2C receptor.
    Type: Application
    Filed: December 28, 2002
    Publication date: June 2, 2005
    Inventors: Gaetan Ladouceur, Emil Velthuisen, Soongyu Choi, Zhonghua Zhang, Yamin Wang, Jeremy Baryza, Philip Coish, Roger Smith, Jinshan Chen
  • Publication number: 20040224970
    Abstract: This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: February 27, 2004
    Publication date: November 11, 2004
    Inventors: Roger A Smith, Stephen J. O'Connor, Wai C. Wong, Soongyu Choi, Harold C.E. Kluender, Jianmei Fan, Zhonghua Zhang, Rico C. Lavoie, Brent L. Podlogar
  • Publication number: 20030100540
    Abstract: The invention is based on evidence that the anti-neoplastic effects of high dose NSAID treatments involve a complex pathway which involves alterations in the expression of genes which regulate a number of biological processes. The invention allows a more accurate molecular picture of cancer response to NSAIDS, and in so doing, allows one to assess the efficacy of a particular NSAID on a particular cancer, and to screen NSAIDS, and drugs generally, for their ability to produce NSAID-like anti-neoplastic effects.
    Type: Application
    Filed: July 26, 2002
    Publication date: May 29, 2003
    Applicant: Vanderbilt University
    Inventors: Zhonghua Zhang, Raymond DuBois