Patents by Inventor Zhonghua Zhang

Zhonghua Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole acetic acid derivatives and their use as pharmaceutical agents
    Publication number: 20060264486
    Abstract: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 23, 2006
    Inventors: Xin Ma, Louis-David Cantin, Soongyu Choi, Roger Clark, Martin Hentemann, Joachim Rudolph, Rico Lavoie, Zhonghua Zhang
  • Preparation and use of 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives for treatment of obesity
    Patent number: 7071207
    Abstract: This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: July 4, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger A. Smith, Stephen J. O'Connor, Wai C. Wong, Soongyu Choi, Harold C. Kluender, Jianmei Fan, Zhonghua Zhang, Rico C. Lavoie, Brent L. Podlogar
  • Preparation and use of 1,5,6,7-tetrahydropyrrolo[3,2-C]pyridine derivatives for the treatment of obesity
    Publication number: 20060122215
    Abstract: This invention relates to 1,5,6,7-tetrahydropynolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: January 18, 2006
    Publication date: June 8, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen O'Connor, Wai Wong, Soongyu Choi, Harold Kluender, Jianmei Fan, Zhonghua Zhang, Rico Lavoie, Brent Podlogar
  • 4-Sulfide/sulfoxide/sulfonyl-1h-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor
    Publication number: 20050119489
    Abstract: Disclosed are 4-sulfide/sulfoxide/sulfonyl-1H-pyrazolyl derivative compounds of formulas (I) or (II): wherein the variables n, R, R1, R2, R3, R3?, R4, R4?, R5 and R6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT2C receptor.
    Type: Application
    Filed: December 28, 2002
    Publication date: June 2, 2005
    Inventors: Gaetan Ladouceur, Emil Velthuisen, Soongyu Choi, Zhonghua Zhang, Yamin Wang, Jeremy Baryza, Philip Coish, Roger Smith, Jinshan Chen
  • Preparation and use of 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives for treatment of obesity
    Publication number: 20040224970
    Abstract: This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: February 27, 2004
    Publication date: November 11, 2004
    Inventors: Roger A Smith, Stephen J. O'Connor, Wai C. Wong, Soongyu Choi, Harold C.E. Kluender, Jianmei Fan, Zhonghua Zhang, Rico C. Lavoie, Brent L. Podlogar
  • Identification of NSAID-regulated genes
    Publication number: 20030100540
    Abstract: The invention is based on evidence that the anti-neoplastic effects of high dose NSAID treatments involve a complex pathway which involves alterations in the expression of genes which regulate a number of biological processes. The invention allows a more accurate molecular picture of cancer response to NSAIDS, and in so doing, allows one to assess the efficacy of a particular NSAID on a particular cancer, and to screen NSAIDS, and drugs generally, for their ability to produce NSAID-like anti-neoplastic effects.
    Type: Application
    Filed: July 26, 2002
    Publication date: May 29, 2003
    Applicant: Vanderbilt University
    Inventors: Zhonghua Zhang, Raymond DuBois