Ultrasonic surgical instruments

- Ethicon Endo-Surgery, LLC

A surgical instrument. The surgical instrument may comprise a transducer and an end effector. The transducer may be configured to provide vibrations along a longitudinal axis at a predetermined frequency and may comprise a piezoelectric stack positioned along the longitudinal axis. The transducer also may comprise a first metallic end mass positioned along the longitudinal axis adjacent a first end of the piezoelectric stack and a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack. The length of the transducer may be greater than or equal to of one wavelength and less than ½ of one wavelength. The end effector may be coupled to the transducer and may extend along the longitudinal axis. The length of the transducer and the end effector may be a multiple of ½ of one wavelength.

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Description

The present application claims the benefit under at least 35 U.S.C. §121 as a divisional of U.S. patent application Ser. No. 11/888,171 filed on Jul. 31, 2007, now U.S. Pat. No. 8,430,898, which is incorporated herein by reference in its entirety.

BACKGROUND

Ultrasonic instruments, including both hollow core and solid core instruments are used for the safe and effective treatment of many medical conditions. Ultrasonic instruments, and particularly solid core ultrasonic instruments, are advantageous because they may be used to cut and/or coagulate tissue using energy in the form of mechanical vibrations transmitted to a surgical end effector at ultrasonic frequencies. Ultrasonic vibrations, when transmitted to organic tissue at suitable energy levels and using a suitable end effector, may be used to cut, dissect or coagulate tissue or to separate muscle tissue off bone. Ultrasonic instruments may be used for open procedures or minimally invasive procedures, such as endoscopic or laparoscopic procedures, wherein the end effector is passed through a trocar to reach the surgical site.

Activating or exciting the single or multiple element end effector (e.g., cutting blade, ball coagulator) of such instruments at ultrasonic frequencies induces longitudinal, transverse or tortional vibratory movement that generates localized heat within adjacent tissue, facilitating both cutting and coagulating. Because of the nature of ultrasonic instruments, a particular ultrasonically actuated end effector may be designed to perform numerous functions, including, for example, cutting and coagulating.

Ultrasonic vibration is induced in the surgical end effector by electrically exciting a transducer, for example. The transducer may be constructed of one or more piezoelectric or magnetostrictive elements in the instrument hand piece. Vibrations generated by the transducer section are transmitted to the surgical end effector via an ultrasonic waveguide extending from the transducer section to the surgical end effector. The waveguides and end effectors may be designed to resonate at the same frequency as the transducer. Therefore, when an end effector is attached to a transducer the overall system frequency is the same frequency as the transducer itself.

The transducer and the end effector may be designed to resonate at two different frequencies and when joined or coupled may resonate at a third frequency. The zero-to-peak amplitude of the longitudinal ultrasonic vibration at the tip, d, of the end effector behaves as a simple sinusoid at the resonant frequency as given by:
d=A sin(ωt)
where:
ω=the radian frequency which equals 2π times the cyclic frequency, f; and
A=the zero-to-peak amplitude.
The longitudinal excursion is defined as the peak-to-peak (p-t-p) amplitude, which is just twice the amplitude of the sine wave or 2A.

Ultrasonic surgical instruments may be divided into two types, single element end effector devices and multiple-element end effector devices. Single element end effector devices include instruments such as scalpels (e.g., blades, sharp hook blades, dissecting hook blades, curved blades) and ball coagulators. Single-element end effector instruments have limited ability to apply blade-to-tissue pressure when the tissue is soft and loosely supported. Substantial pressure may be necessary to effectively couple ultrasonic energy to the tissue. This inability to grasp the tissue results in a further inability to fully coapt tissue surfaces while applying ultrasonic energy, leading to less-than-desired hemostasis and tissue joining. In these cases, multiple-element end effectors may be used. Multiple-element end effector devices, such as clamping coagulators, include a mechanism to press tissue against an ultrasonic blade that can overcome these deficiencies.

One drawback of existing ultrasonic instruments is their size. The large size and bulkiness of existing ultrasonic instruments can make it more difficult for clinicians to manipulate the instruments in surgical environments where fine movement is required and can also obstruct the vision of the clinician. This may limit the usefulness of ultrasonic instruments in small surgical sites. Also, because of the bulkiness of existing transducers, many existing ultrasonic instruments position the transducer proximal from the end effector, requiring an extended, and often relatively inflexible wave guide. As a result, articulation of the end effector and blade may be difficult or impossible. This limits the usefulness of existing ultrasonic instruments in endoscopic and laparoscopic surgical environments.

SUMMARY

In one general aspect, the various embodiments are directed to a surgical instrument. The surgical instrument may comprise a transducer and an end effector. The transducer may be configured to provide vibrations along a longitudinal axis at a predetermined frequency and may comprise a piezoelectric stack positioned along the longitudinal axis. The transducer also may comprise a first metallic end mass positioned along the longitudinal axis adjacent a first end of the piezoelectric stack and a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack. The length of the transducer may be greater than or equal to ¼ of one wavelength and less than ½ of one wavelength. The end effector may be coupled to the transducer and may extend along the longitudinal axis. The length of the transducer and the end effector may be a multiple of ½ of one wavelength.

In another general aspect, the various embodiments are directed to another surgical instrument comprising a transducer and an end effector. The transducer may be configured to provide vibrations along a longitudinal axis at a predetermined frequency. The transducer may comprise a piezoelectric stack positioned along the longitudinal axis, a first metallic end mass positioned along the longitudinal axis adjacent a first end of the piezoelectric stack, and a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack. The end effector may extend along the longitudinal axis and be coupled to the transducer. According to various embodiments, the amplitude gain of the transducer may be equal to one.

In yet another general aspect, the various embodiments are directed to a surgical instrument. The surgical instrument may comprise a transducer configured to provide vibrations along a longitudinal axis at a predetermined frequency and a housing coupled to the transducer. The transducer may comprise a piezoelectric stack, a first metallic end mass and a second metallic end mass. The piezoelectric stack may be positioned along the longitudinal axis about ¼ of one wavelength from the first end of the transducer. The first and second metallic end masses may be positioned along the longitudinal axis adjacent first and second respective ends of the piezoelectric stack. According to various embodiments, the length of the transducer is equal to about one wavelength. Also, the transducer may define a first mounting point and a second mounting point, where the first mounting point is positioned ¼ of one wavelength from the first end of the transducer along the longitudinal axis, and the second mounting point is positioned % of one wavelength from a second end of the transducer along the longitudinal axis. The housing may be coupled to the transducer at the first and second mounting points.

In an additional general aspect, the various embodiments are directed to a surgical instrument comprising a flexible member, a transducer, and an end effector positioned distally from the transducer. The transducer may be coupled to a distal portion of the flexible member and may be positioned to provide vibrations along a longitudinal axis at a predetermined frequency. The transducer may comprise: a piezoelectric stack positioned along the longitudinal axis, a first metallic end mass and a second metallic end mass. The first and second metallic end masses may be positioned along the longitudinal axis adjacent first and second respective ends of the piezoelectric stack.

In another general aspect, the various embodiments are directed to a surgical instrument comprising a surgical device, a sleeve configured to receive the surgical device and a rail positioned along an interior portion of the sleeve. The surgical device may comprise a feature for receiving the rail and may be slidable along the rail. Also, the surgical device may comprise a transducer positioned to provide vibrations along a longitudinal axis at a predetermined frequency and an end effector positioned distally from the transducer.

In yet another general aspect, the various embodiments are directed to a surgical instrument comprising a first operation member and a second operation member. The first and second operation members may be pivotable towards one another about a pivot point. The surgical instrument also may comprise a transducer positioned along a longitudinal axis of the first operation member to provide vibrations at a predetermined frequency along the longitudinal axis. In addition, the surgical instrument may comprise an end effector coupled to the transducer and extending distally along the longitudinal axis. A clamp pad may be coupled to the second operation member and may move towards the end effector when the first operation member and the second operation member are pivoted towards one another about the pivot point.

FIGURES

The novel features of the various embodiments are set forth with particularity in the appended claims. The various embodiments, however, both as to organization and methods of operation, together with further objects and advantages thereof, may best be understood by reference to the following description, taken in conjunction with the accompanying drawings as follows.

FIG. 1 illustrates one embodiment of an ultrasonic system.

FIG. 2 illustrates one embodiment of a connection union/joint for an ultrasonic instrument.

FIG. 3 illustrates an exploded perspective view of one embodiment of a surgical instrument that may be employed with the ultrasonic system shown in FIG. 1.

FIG. 4 illustrates one embodiment of a chart showing the displacement of a standing waveform over a full wavelength.

FIG. 5 illustrates one embodiment of a full-wavelength ultrasonic transducer having two mounting points comprising flanges.

FIG. 6 illustrates one embodiment of a full-wavelength ultrasonic transducer having two mounting points defining grooves.

FIGS. 7-8 illustrate embodiments of a full-wavelength ultrasonic transducer having one mounting point comprising a flange and one mounting point defining a groove.

FIG. 9 illustrates one embodiment of a full-wavelength ultrasonic transducer having two mounting points, each comprising a pair of flanges.

FIG. 10 illustrates one embodiment of a portion of an ultrasonic device including a housing, a transducer and an end effector.

FIG. 11 illustrates one embodiment of a portion of an ultrasonic device including an ultrasonic transducer and end effector.

FIG. 12 illustrates one embodiment of a quarter-wavelength ultrasonic transducer.

FIG. 12A illustrates a cut-away view of one embodiment of the quarter-wave ultrasonic transducer shown in FIG. 12.

FIG. 13 illustrates one embodiment of an ultrasonic transducer.

FIG. 14 illustrates one embodiment of an ultrasonic transducer having first and second piezoelectric stacks.

FIG. 15 illustrates one embodiment of an ultrasonic instrument.

FIG. 16 illustrates one embodiment of an ultrasonic instrument having finger loops.

FIG. 17 illustrates one embodiment of the ultrasonic instrument shown in FIG. 16.

FIG. 18 illustrates one embodiment of an ultrasonic instrument.

FIG. 19 illustrates one embodiment of the ultrasonic instrument shown in FIG. 18.

FIG. 20 illustrates one embodiment of an ultrasonic end effector and transducer assembly positioned at the distal end of a flexible member.

FIG. 21 illustrates one embodiment of an surgical instrument for use in an endoscopic or laparoscopic environment.

FIG. 22 illustrates one embodiment of the surgical instrument shown in FIG. 21.

FIG. 23 illustrates one embodiment of the surgical instrument shown in FIG. 21.

FIG. 24 illustrates one embodiment of the surgical instrument shown in FIG. 21 including a flexible lasso.

FIG. 25 illustrates one embodiment of the surgical instrument shown in FIG. 24.

FIG. 26 illustrates one embodiment of the surgical instrument shown in FIG. 24.

DESCRIPTION

Before explaining the various embodiments in detail, it should be noted that the embodiments are not limited in their application or use to the details of construction and arrangement of parts illustrated in the accompanying drawings and description. The illustrative embodiments may be implemented or incorporated in other embodiments, variations and modifications, and may be practiced or carried out in various ways. For example, the surgical instruments and blade configurations disclosed below are illustrative only and not meant to limit the scope or application thereof. Furthermore, unless otherwise indicated, the terms and expressions employed herein have been chosen for the purpose of describing the illustrative embodiments for the convenience of the reader and are not to limit the scope thereof.

Examples of ultrasonic surgical instruments and blades are disclosed in U.S. Pat. Nos. 5,322,055 and 5,954,736, 6,309,400 B2, 6,278,218B1, 6,283,981 B1, and 6,325,811 B1, which are incorporated herein by reference in their entirety. These references disclose ultrasonic surgical instrument designs and blade designs where a longitudinal mode of the blade is excited. The result is a longitudinal standing wave within the instrument. Accordingly, the instrument has nodes, where the longitudinal motion is equal to zero, and anti-nodes, where the longitudinal motion is at its maximum. The instrument's tissue effector is often positioned at an anti-node, maximizing its longitudinal motion.

Various embodiments will now be described to provide an overall understanding of the principles of the structure, function, manufacture, and use of the devices and methods disclosed herein. One or more examples of these embodiments are illustrated in the accompanying drawings. Those of ordinary skill in the art will understand that the devices and methods specifically described herein and illustrated in the accompanying drawings are non-limiting exemplary embodiments and that the scope of the various embodiments is defined solely by the claims. The features illustrated or described in connection with one exemplary embodiment may be combined with the features of other embodiments. Such modifications and variations are intended to be included within the scope of the claims.

FIG. 1 illustrates one embodiment of an ultrasonic system 10. The ultrasonic system 10 may comprise an ultrasonic signal generator 12 coupled to an ultrasonic transducer 14, a hand piece assembly 60 comprising a hand piece housing 16, and an ultrasonically actuatable single element end effector or ultrasonically actuatable blade 50. The ultrasonic transducer 14, which is known as a “Langevin stack”, generally includes a transduction portion 18, a first resonator portion or end-bell 20, and a second resonator portion or fore-bell 22, and ancillary components. The total construction of these portions is a resonator. The ultrasonic transducer 14 is preferably an integral number of one-half system wavelengths (nπ/2: wherein “n” is any positive integer; e.g., n=1, 2, 3 . . . ) in length as will be described in more detail later. An acoustic assembly 24 includes the ultrasonic transducer 14, a nose cone 26, a velocity transformer 28, and a surface 30.

It will be appreciated that the terms “proximal” and “distal” are used herein with reference to a clinician gripping the hand piece assembly 60. Thus, the end effector 50 is distal with respect to the more proximal hand piece assembly 60. It will be further appreciated that, for convenience and clarity, spatial terms such as “top” and “bottom” also are used herein with respect to the clinician gripping the hand piece assembly 60. However, surgical instruments are used in many orientations and positions, and these terms are not intended to be limiting and absolute.

The distal end of the end-bell 20 is connected to the proximal end of the transduction portion 18, and the proximal end of the fore-bell 22 is connected to the distal end of the transduction portion 18. The fore-bell 22 and the end-bell 20 have a length determined by a number of variables, including the thickness of the transduction portion 18, the density and modulus of elasticity of the material used to manufacture the end-bell 20 and the fore-bell 22, and the resonant frequency of the ultrasonic transducer 14. The fore-bell 22 may be tapered inwardly from its proximal end to its distal end to amplify the ultrasonic vibration amplitude as the velocity transformer 28, or alternately may have no amplification. A suitable vibrational frequency range may be about 20 Hz to 120 kHz and a well-suited vibrational frequency range may be about 30-100 kHz and one example operational vibrational frequency may be approximately 55.5 kHz, for example.

Piezoelectric stack 31 may include one or more piezoelectric elements 32, which may be fabricated from any suitable material, such as, for example, lead zirconate-titanate, lead meta-niobate, lead titanate, barium titanate or other piezoelectric ceramic material. Each of positive electrodes 34, negative electrodes 36, and the piezoelectric elements 32 may have a bore extending through the center. The positive and negative electrodes 34 and 36 are electrically coupled to wires 38 and 40, respectively. The wires 38 and 40 are encased within a cable 42 and electrically connectable to the ultrasonic signal generator 12 of the ultrasonic system 10.

The ultrasonic transducer 14 of the acoustic assembly 24 converts the electrical signal from the ultrasonic signal generator 12 into mechanical energy that results in primarily a standing acoustic wave of longitudinal vibratory motion of the ultrasonic transducer 14 and the end effector 50 at ultrasonic frequencies. In another embodiment, the vibratory motion of the ultrasonic transducer may act in a different direction. For example, the vibratory motion may comprise a local longitudinal component of a more complicated motion of the tip of the ultrasonic system 10. A suitable generator is available as model number GEN01, from Ethicon Endo-Surgery, Inc., Cincinnati, Ohio. When the acoustic assembly 24 is energized, a vibratory motion standing wave is generated through the acoustic assembly 24. The ultrasonic system 10 may be designed to operate at a resonance such that an acoustic standing wave pattern of a predetermined amplitude is produced. The amplitude of the vibratory motion at any point along the acoustic assembly 24 may depend upon the location along the acoustic assembly 24 at which the vibratory motion is measured. A minimum or zero crossing in the vibratory motion standing wave is generally referred to as a node (e.g., where motion is usually minimal), and a local absolute value maximum or peak in the standing wave is generally referred to as an anti-node (e.g., where motion is usually maximal). The distance between an anti-node and its nearest node is one-quarter wavelength (λ/4).

The wires 38 and 40 transmit an electrical signal from the ultrasonic signal generator 12 to the positive electrodes 34 and the negative electrodes 36. The piezoelectric elements 32 are energized by the electrical signal supplied from the ultrasonic signal generator 12 in response to a switch 44 to produce an acoustic standing wave in the acoustic assembly 24. The switch 44 may be configured to be actuated by a clinician's foot. The electrical signal causes the piezoelectric elements 32 to expand and contract in a continuous manner along the axis of the voltage gradient, producing longitudinal waves of ultrasonic energy. The straining of the elements causes large alternating compressional and tensile forces within the material. These forces in the piezoelectric elements 32 manifest as repeated small displacements resulting in large alternating compression and tension forces within the material. The repeated small displacements cause the piezoelectric elements 32 to expand and contract in a continuous manner along the axis of the voltage gradient, producing longitudinal waves of ultrasonic energy. The ultrasonic energy is transmitted through the acoustic assembly 24 to the end effector 50 via a transmission component or ultrasonic transmission waveguide 104. According to various embodiments, the waveguide 104, end effector 50 and blade 52 may all be referred to generally as the end effector.

In order for the acoustic assembly 24 to deliver energy to the end effector 50, all components of the acoustic assembly 24 must be acoustically coupled to the end effector 50. The distal end of the ultrasonic transducer 14 may be acoustically coupled at the surface 30 to the proximal end of the ultrasonic transmission waveguide 104 by a threaded connection such as a stud 48.

The components of the acoustic assembly 24 are preferably acoustically tuned such that the length of any assembly is an integral number of one-half wavelengths (nλ/2), where the wavelength λ, is the wavelength of a pre-selected or operating longitudinal vibration drive frequency fd of the acoustic assembly 24, and where n is any positive integer. It is also contemplated that the acoustic assembly 24 may incorporate any suitable arrangement of acoustic elements.

The ultrasonic end effector 50 may have a length substantially equal to an integral multiple of one-half system wavelengths (λ/2). A distal end or blade 52 of the ultrasonic end effector 50 may be disposed near an antinode in order to provide the maximum longitudinal excursion of the distal end. When the transducer assembly is energized, the distal end 52 of the ultrasonic end effector 50 may be configured to move in the range of, for example, approximately 10 to 500 microns peak-to-peak, and preferably in the range of about 30 to 150 microns at a predetermined vibrational frequency.

The ultrasonic end effector 50 may be coupled to the ultrasonic transmission waveguide 104. The ultrasonic end effector 50 and the ultrasonic transmission guide 104 as illustrated are formed as a single unit construction from a material suitable for transmission of ultrasonic energy such as, for example, Ti6A14V (an alloy of Titanium including Aluminum and Vanadium), Aluminum, Stainless Steel, or other suitable materials. Alternately, the ultrasonic end effector 50 may be separable (and of differing composition) from the ultrasonic transmission waveguide 104, and coupled by, for example, a stud, weld, glue, quick connect, or other suitable known methods. The ultrasonic transmission waveguide 104 may have a length substantially equal to an integral number of one-half system wavelengths (λ/2), for example. The ultrasonic transmission waveguide 104 may be preferably fabricated from a solid core shaft constructed out of material suitable to propagate ultrasonic energy efficiently, such as the titanium alloy discussed above, (e.g., Ti-6Al-4V) or any suitable aluminum alloy, or other alloys, for example.

The ultrasonic transmission waveguide 104 comprises a longitudinally projecting attachment post 54 at a proximal end to couple to the surface 30 of the ultrasonic transmission waveguide 104 by a threaded connection such as the stud 48. In the embodiment illustrated in FIG. 1, the ultrasonic transmission waveguide 104 comprises a plurality of stabilizing silicone rings or compliant supports 56 positioned at a plurality of nodes. The silicone rings 56 dampen undesirable vibration and isolate the ultrasonic energy from an outer sheath 58 assuring the flow of ultrasonic energy in a longitudinal direction to the distal end 52 of the end effector 50 with maximum efficiency.

As shown in FIG. 1, the outer sheath 58 protects a user of the ultrasonic instrument 10 and a patient from the ultrasonic vibrations of the ultrasonic transmission waveguide 104. The sheath 58 generally includes a hub 62 and an elongated tubular member 64. The tubular member 64 is attached to the hub 62 and has an opening extending longitudinally therethrough. The sheath 58 may be threaded or snapped onto the distal end of the housing 16. The ultrasonic transmission waveguide 104 extends through the opening of the tubular member 64 and the silicone rings 56 isolate the ultrasonic transmission waveguide 104 from the outer sheath 58. The outer sheath 58 may be attached to the waveguide 104 with an isolator pin 112. The hole in the waveguide 104 may occur nominally at a displacement. The waveguide 104 may screw or snap onto the hand piece assembly 60 by the stud 48. The flat portions of the hub 62 may allow the assembly to be torqued to a required level.

The hub 62 of the sheath 58 is preferably constructed from ULTEM®, and the tubular member 64 is fabricated from stainless steel. Alternatively, the ultrasonic transmission waveguide 104 may have polymeric material surrounding it to isolate it from outside contact.

The distal end of the ultrasonic transmission waveguide 104 may be coupled to the proximal end of the end effector 50 by an internal threaded connection, preferably at or near an antinode. It is contemplated that the end effector 50 may be attached to the ultrasonic transmission waveguide 104 by any suitable means, such as a welded joint or the like. Although the end effector 50 may be detachable from the ultrasonic transmission waveguide 104, it is also contemplated that the end effector 50 and the ultrasonic transmission waveguide 104 may be formed as a single unitary piece.

FIG. 2 illustrates one embodiment of a connection union/joint 70 for an ultrasonic instrument. The connection union/joint 70 may be formed between the attachment post 54 of the ultrasonic transmission waveguide 104 and the surface 30 of the velocity transformer 28 at the distal end of the acoustic assembly 24. The proximal end of the attachment post 54 comprises a female threaded substantially cylindrical recess 66 to receive a portion of the threaded stud 48 therein. The distal end of the velocity transformer 28 also may comprise a female threaded substantially cylindrical recess 68 to receive a portion of the threaded stud 40. The recesses 66, 68 are substantially circumferentially and longitudinally aligned. In another embodiment (not shown), the stud is an integral component of the end of the ultrasonic transducer. For example, the treaded stud and the velocity transformer may be of a single unit construction with the stud projecting from a distal surface of the velocity transformer at the distal end of the acoustic assembly. In this embodiment, the stud is not a separate component and does not require a recess in the end of the transducer.

FIG. 3 illustrates an exploded perspective view of one embodiment of a sterile ultrasonic surgical instrument 100. The ultrasonic surgical instrument 100 may be employed with the above-described ultrasonic system 10. However, as described herein, those of ordinary skill in the art will understand that the various embodiments of the ultrasonic surgical instruments disclosed herein as well as any equivalent structures thereof could conceivably be effectively used in connection with other known ultrasonic surgical instruments without departing from the scope thereof. Thus, the protection afforded to the various ultrasonic surgical blade embodiments disclosed herein should not be limited to use only in connection with the exemplary ultrasonic surgical instrument described above.

The ultrasonic surgical instrument 100 may be sterilized by methods known in the art such as, for example, gamma radiation sterilization, Ethelyne Oxide processes, autoclaving, soaking in sterilization liquid, or other known processes. In the illustrated embodiment, an ultrasonic transmission assembly 102, which may be generally referred to as the end effector, may include the ultrasonic end effector 50 and the ultrasonic transmission waveguide 104. The ultrasonic end effector 50 and the ultrasonic transmission waveguide 104 are illustrated as a single unit construction from a material suitable for transmission of ultrasonic energy such as, for example, Ti6Al4V (an alloy of Titanium including Aluminum and Vanadium), Aluminum, Stainless Steel, or other known materials. Alternately, the ultrasonic end effector 50 may be separable (and of differing composition) from the ultrasonic transmission waveguide 104, and coupled by, for example, a stud, weld, glue, quick connect, or other known methods. The ultrasonic transmission waveguide 104 may have a length substantially equal to an integral number of one-half system wavelengths (nλ/2), for example. The ultrasonic transmission waveguide 104 may be preferably fabricated from a solid core shaft constructed out of material that propagates ultrasonic energy efficiently, such as titanium alloy (e.g., Ti-6Al-4V) or an aluminum alloy, for example.

In the embodiment illustrated in FIG. 3, the ultrasonic transmission waveguide 104 is positioned in an outer sheath 106 by a mounting O-ring 108 and a sealing ring 110. One or more additional dampers or support members (not shown) also may be included along the ultrasonic transmission waveguide 104. The ultrasonic transmission waveguide 104 is affixed to the outer sheath 106 by a mounting pin 112 that passes through mounting holes 114 in the outer sheath 106 and a mounting slot 116 in the ultrasonic transmission waveguide 104.

FIG. 4 illustrates one cycle or wavelength of a standing waveform 400 as it would be formed in a full-wavelength transducer. The length of the waveform 400, and thus the length of the transducer, may depend on system frequency and the material from which the transducer is made. For example, in a transducer made of titanium and excited at a frequency of 55.5 kHz, one wavelength may be approximately 3.44 inches. Because it is a full-wavelength, the waveform 400 includes two nodes 402 where the displacement is zero. These are the zero-displacement nodes 402 and they occur at λ/4 and 3λ/4, or λ/4 from the respective edges of the waveform 400 on the x-axis. Mounting points for the transducer may be positioned to correspond to the zero-displacement nodes 402.

FIGS. 5-9 illustrate embodiments of full-wavelength ultrasonic transducers that may be used in any suitable ultrasonic system including, for example, the system 10 described above. Because the full-wavelength transducers are longer than typical half-wavelength transducers, they may include a longer piezoelectric stack. For this reason, full-wavelength transducers may be able to deliver power comparable to that of existing larger-diameter half-wavelength transducers. Also, full-wavelength transducers, such as the embodiments shown in FIGS. 5-9 may include multiple mounting points. This may provide increased resistance to prevent the transducers from pivoting within the hand piece housing in response to forces applied at the end effector, and also may provide increased damping to prevent unwanted vibration modes such as transverse and tortional.

FIG. 5 illustrates one embodiment of a full-wavelength ultrasonic transducer 500 having two mounting points 506, 508 comprising flanges 514, 516. The transducer 500 may generally include a piezoelectric stack 510, which may include a series of piezoelectric elements 512. Optionally, the transducer 500 may be divided into an active stage 504, including the piezoelectric stack 510, and a gain stage 502, which may provide amplitude gain. The gain stage 502, for example, may involve a change in the cross-sectional area of the transducer 500 positioned at or near the zero displacement node 402. As described above, the mounting points 514, 516 may be located at the respective zero-displacement nodes in the transducer 500. This may prevent significant amounts of transverse vibration from being transferred from the transducer 500 to the hand piece housing (not shown).

The mounting points 506, 508 may take any suitable form. For example, in the embodiment shown in FIG. 5, the mounting points 506, 508 comprise flanges 514, 516 raised above the surface the transducer 500. The hand piece housing, or other frame member, may then include corresponding shapes for receiving the flanges 514, 516. FIG. 6 illustrates one embodiment of a full-wavelength ultrasonic transducer 600 having two mounting points 506, 508 defining grooves 530, 528. The hand piece housing or other frame member (not shown) may include a corresponding feature for coupling with the grooves 530, 528. Also, for example, an O-ring or other type of elastomeric member (not shown) may be positioned within one or both of the groove 530, 528. The O-ring may interface with the hand piece housing or other frame member. FIG. 7 illustrates one embodiment of a full-wavelength ultrasonic transducer 700 having one mounting point 506 defining a groove 526 and one mounting point 508 comprising a flange 524. FIG. 8 illustrates one embodiment of a full-wavelength ultrasonic transducer 800 having one mounting point 506 comprising a flange 522 and one mounting point 508 defining a groove 520. FIG. 9 illustrates one embodiment of a full-wavelength ultrasonic transducer 900 having two mounting points 506, 508. Each of the mounting points 506 508 may comprise a pair of flanges which together define grooves 532, 534. In this way, an O-ring may be held stationary by the flanges without the need for a groove extending into the transducer 500.

FIG. 10 illustrates an embodiment of a portion 1000 of an ultrasonic device including a housing 1002, a transducer 1004 and an end effector 1006. The transducer 1004 may include mounting points 1008 and 1009 of different dimensions. For example, in the embodiment shown in FIG. 10, the distal mounting point 1008 is shown with a smaller dimension than the proximal mounting point 1009. This may simplify manufacturing by allowing the transducer to be inserted into the housing 1002 from the proximal end.

FIG. 11 illustrates one embodiment of a portion of an ultrasonic device including an ultrasonic transducer 1100 and end effector 1102. The transducer 1100 may include a piezoelectric stack 1104 comprising one or more piezoelectric disks 1106. The transducer 1100 may be constructed as a unity gain or near unity gain transducer. For example, the amplitude of the standing wave at the distal end of the transducer 1100 may be substantially similar to the amplitude of the standing wave at the proximal end of the transducer 1100. In one example embodiment, the amplitude at the distal end of the transducer 1100 may be between 1 and 5 microns peak-to-peak. As described above, it may be desirable for the end effector 1102 to displace at an amplitude of, for example, between 10 and 100 microns peak-to-peak. Accordingly, it may be desirable to configure the end effector 1102 to implement an amplitude gain between its proximal and distal ends. The end effector 1102 is shown with a series of relatively large diameter sections 1110 and relatively small diameter sections 1108. Each transition from a large diameter section 1110 to a small diameter section 1108 may bring about an amplitude gain when the transition occurs near a zero-displacement node. According to various embodiments, the total amplitude gain of the transducer 1100 and end effector 1102 may be between about 10 and 50. For example, the total amplitude gain may be about 40.

FIGS. 12-14 show embodiments of various transducers with a length less than one half (½) of one wavelength. Because of their small size, the embodiments shown in FIGS. 12-14 may be useful in smaller ultrasonic applications where lower ultrasonic power is required. In general, components in ultrasonic surgical instruments are dimensioned as integral multiples of half wavelengths (nλ/2). For example, transducers, waveguides and end effectors have a length that is usually an integral multiple of λ/2. Individual components, however, may have a length of less than λ/2, provided that the system as a whole (e.g., the transducer plus any end effector) has a length that is a multiple of λ/2. For example, a transducer, according to various embodiments, may have a length of between λ/4 and λ/2.

FIG. 12 illustrates one embodiment of a quarter-wavelength (λ/4) ultrasonic transducer 1200. The transducer 1200 may include a flange 1208 and a mass 1210 with a piezoelectric stack 1204 positioned therebetween. The flange 1208 and mass may be made from any suitable material including, for example, metallic materials such as titanium or an alloy thereof. According to various embodiments, the flange 1208 may include an O-ring or other elastomeric material member (not shown) that may provide sealing as well as damping of vibrations within the flange 1208. The O-ring may be mounted within a groove or other feature of the flange (not shown), for example, as illustrated above in FIGS. 5-9. Also, according to various embodiments, the flange 1208 may be replaced with a second mass having radial dimensions similar to those of the piezoelectric stack 1204 and the mass 1210. FIG. 12A illustrates a cut-away view of one embodiment of the quarter-wave ultrasonic transducer 1200 illustrating a stud 1212. The stud 1212 may engage the elements 1206 of the piezoelectric stack 1204, placing them in compression. This may prevent the individual piezoelectric elements 1206 from being subjected to tension, which may cause mechanical failure.

In the embodiment shown in FIG. 12, a zero-displacement node 1202 of the transducer 1200 is indicated. The node 1202 may be located one quarter of one wavelength from the opposite edge 1220 of the transducer 1200. FIG. 13 illustrates one embodiment of an ultrasonic transducer 1300 that may be longer than a quarter wavelength. For example, the transducer 1300 may be dimensioned so that the node 1202 falls within flange 1208. In this way, the transducer stack 1204 may be closer to the node 1202. This may increase the effectiveness of the stack 1204. FIG. 14 illustrates one embodiment of an ultrasonic transducer 1400 having first and second piezoelectric stacks 1408 and 1404. The stacks 1404 and 1408 may be separated by a flange 1416, with masses 1412 and 1414 on the respective ends. According to various embodiments, the transducer 1400 may be between λ/4 and λ/2 in length.

FIGS. 15-19 illustrate embodiments of ultrasonic surgical devices having first and second operation members pivotable towards one another about a pivot point. A first operation member may comprise a transducer and an end effector coupled to the transducer. A second operation member may comprise a clamp pad. When the operation members are pivoted toward one another the clamp pad may be brought toward the end effector. The surgical instruments may be arranged according to any suitable configuration. For example, the embodiments shown in FIG. 15-17 may be arranged in a tweezer-like configuration. Also, for example, the embodiments shown in FIGS. 18-19 may be arranged with a scissor or pistol-like grip.

FIG. 15 illustrates one embodiment of a surgical instrument 1500 having a first member 1504 and a second member 1502. The members 1502 may be pivotable toward one another about pivot point 1520. A support member 1512 may be positioned at the pivot point 1520 and may resist movements of the members 1504, 1502 toward or away from one another. According to various embodiments, the member 1502 may comprise a transducer assembly 1505 and an end effector 1506. The end effector 1506 may include a waveguide assembly 1507 and a blade 1508. A port 1509 may receive one or more wires (not shown) connecting the transducer assembly 1505 to a signal generator (not shown in FIG. 15). The end effector 1506 may comprise a waveguide and a protective sheath to prevent the waveguide from contacting tissue. The blade 1508 may operate as described above to cut and/or coagulate tissue. When the members 1504 and 1502 are pivoted together, the end effector 1508 may come into contact with the clamp pad 1510, allowing a clinician to apply pressure to tissue in contact with the blade 1508.

FIG. 16 illustrates one embodiment of an ultrasonic instrument 1600 similar to instrument 1500 and including finger loops 1604. The surgical instrument 1600 also may include a hinge 1602 at pivot point 1520. The hinge 1602 may allow the members 1502, 1504 to pivot freely about the pivot point 1520. The finger loops 1604 may be positioned on the members 1502, 1504 distally from the pivot point 1520. A clinician may use the finger loops 1604 to manipulate the members 1502, 1504. Also, according to various embodiments, the finger loops 1604 may be rotatable relative to the members 1502, 1504. For example, FIG. 17 illustrates one embodiment of the instrument 1600 with the finger loops 1604 rotated 90° relative to their position as shown in the embodiment of FIG. 16. It will be appreciated that the finger loops 1604 may be provided with holes large enough to fit multiple fingers.

FIGS. 18-19 illustrate one embodiment of an ultrasonic instrument 1800. The instrument 1800 includes a first member 1802 and a second member 1804 pivotable towards one another about pivot point 1806. The first member 1802 may comprise a transducer assembly 1812 and an end effector 1808. The end effector 1808 includes a waveguide assembly 1810 and a blade 1811. The second member 1804 may comprise a clamp pad 1814 opposite blade 1811. When the members 1802, 1804 are pivoted towards one another, the clamp pad 1814 may come into contact with the blade 1811. In this way, a clinician may exert pressure on tissue in contact with the end effector 1808. Finger loops 1816 and 1818 may be positioned relative to the pivot point 1806 to allow a clinician to pivot the members 1802 and 1804 about the pivot point 1806 in a scissor-like manner. The finger loops 1816 and 1818 may be optionally angled, as shown, to create a “pistol-grip” configuration. It will be appreciated that the finger loops 1818 and 1816 may be provided with holes large enough to fit multiple fingers.

FIG. 20 illustrates one embodiment of an ultrasonic end effector 2006 and transducer assembly 2004 positioned at the distal end of a flexible member 2002. In use, other components, such as a handle, may be connected to the portion 2000.

FIGS. 21-26 show various embodiments of a surgical instrument that may be used in endoscopic or laparoscopic environments. The surgical instrument may comprise a surgical device including a transducer and an end effector. The surgical instrument also may comprise a sleeve configured to receive the surgical device. The sleeve may include a rail positioned along its interior portion. The surgical device may comprise a feature for receiving the rail. In use, the surgical device may slide within the sleeve along the rail. This may allow the surgical device to be introduced and removed from a surgical site during endoscopic or laproscopic surgical procedures.

FIG. 21 illustrates one embodiment of an ultrasonic instrument 2101 for use in an endoscopic or laparoscopic environment. The surgical instrument 2101 may be housed within a sleeve 2104. The sleeve 2104 may be connected to an endoscope sleeve 2102 for housing the endoscope 2100. Portions of the surgical instrument 2101, e.g., a control wire, may extend through the sleeve 2104 to a clinician, who may control the surgical instrument 2101. The surgical instrument 2101 may be slidable within the sleeve 2104 into a position in view of the endoscope 2100, as shown.

The surgical instrument 2101 may comprise a transducer 2112, an end effector 2110, and a clamp arm 2106. The clamp arm 2106 may include a clamp pad 2108. In use, the clamp pad 2108 may be brought into contact with the end effector 2110 to provide a clamping force between tissue and the end effector 2110. For example, the surgical instrument may be maneuvered into position relative to the tissue. The end effector 2110 then may be energized and brought into contact with the tissue. According to various embodiments, the end effector 2110 may move toward the clamp arm 2106, or the clamp arm 2106 may move toward the end effector 2110. FIGS. 22-23 shows embodiments of the surgical instrument 2101 where the clamp arm 2106 comprises two support members 2114, 2116. The embodiments of FIGS. 22-23 may be utilized by drawing a loop or wedge of tissue between the two support members.

FIGS. 24-26 illustrate embodiments of a surgical instrument 2401 including a flexible lasso 2402. The lasso 2402 may be extendable and retractable from the surgical instrument 2401 to bring tissue into contact with the end effector 2110. For example, a clinician may extend the lasso 2402 to ensnare a polyp or other type of tissue. The clinician then may retract the lasso 2402 to pull the polyp or other tissue into contact with the end effector 2110, which may be energized to cut and/or coagulate the tissue. The lasso 2402 may be embodied as a cable, or as a stiff ribbon material. It will be appreciated that a lasso 2402 made of stiff ribbon material may help guide tissue to the tip of the end effector 2110.

The instruments disclosed herein can be designed to be disposed of after a single use, or they can be designed to be used multiple times. In either case, however, the instrument may be reconditioned for reuse after at least one use. Reconditioning can include any combination of the steps of disassembly of the instrument, followed by cleaning or replacement of particular elements, and subsequent reassembly. In particular, the instrument may be disassembled, and any number of particular elements or components of the instrument may be selectively replaced or removed in any combination. Upon cleaning and/or replacement of particular components, the instrument may be reassembled for subsequent use either at a reconditioning facility, or by a surgical team immediately prior to a surgical procedure. Those skilled in the art will appreciate that reconditioning of a instrument may utilize a variety of techniques for disassembly, cleaning/replacement, and reassembly. Use of such techniques, and the resulting reconditioned instrument; are all within the scope of the present application.

Preferably, the various embodiments described herein will be processed before surgery. First, a new or used instrument is obtained and if necessary cleaned. The instrument can then be sterilized. In one sterilization technique, the instrument is placed in a closed and sealed container, such as a plastic or TYVEK® bag. The container and instrument are then placed in a field of radiation that can penetrate the container, such as gamma radiation, x-rays, or high-energy electrons. The radiation kills bacteria on the instrument and in the container. The sterilized instrument can then be stored in the sterile container. The sealed container keeps the instrument sterile until it is opened in the medical facility.

It is preferred that the instrument is sterilized. This can be done by any number of ways known to those skilled in the art including beta or gamma radiation, ethylene oxide, steam.

Although various embodiments have been described herein, many modifications and variations to those embodiments may be implemented. For example, different types of end effectors may be employed. Also, where materials are disclosed for certain components, other materials may be used. The foregoing description and following claims are intended to cover all such modification and variations.

Other than the operating examples, or where otherwise indicated, all numbers expressing quantities of ingredients, processing conditions and the like used in the specification and claims are to be understood as being modified in all instances by the term “about”. Accordingly, unless indicated to the contrary, the numerical parameters set forth in the following specification and attached claims are approximations that may vary depending upon the desired properties sought to be obtained.

Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the disclosure are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. Any numerical values, however, inherently contain certain errors, such as, for example, equipment and/or operator error, necessarily resulting from the standard deviation found in their respective testing measurements.

Also, it should be understood that any numerical range recited herein is intended to include all sub-ranges subsumed therein. For example, a range of “1 to 10” is intended to include all sub-ranges between (and including) the recited minimum value of 1 and the recited maximum value of 10, that is, having a minimum value equal to or greater than 1 and a maximum value of less than or equal to 10.

Any patent, publication, or other disclosure material, in whole or in part, that is said to be incorporated by reference herein is incorporated herein only to the extent that the incorporated materials does not conflict with existing definitions, statements, or other disclosure material set forth in this disclosure. As such, and to the extent necessary, the disclosure as explicitly set forth herein supersedes any conflicting material incorporated herein by reference. Any material, or portion thereof, that is said to be incorporated by reference herein, but which conflicts with existing definitions, statements, or other disclosure material set forth herein will only be incorporated to the extent that no conflict arises between that incorporated material and the existing disclosure material.

Claims

1. A surgical instrument, comprising:

a first operation member;
a second operation member, wherein at least one of the first operation member or second operation member is pivotable towards the other operation member about a pivot point;
a transducer positioned along a longitudinal axis of the first operation member to provide vibrations along the longitudinal axis, wherein the transducer is at a position distal from the pivot point, and wherein the transducer comprises: a piezoelectric stack positioned parallel to the longitudinal axis; a first metallic end mass positioned parallel to the longitudinal axis adjacent a first end of the piezoelectric stack; a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack, wherein a length of the transducer is greater than ½ of one wavelength; a first mounting point positioned at a distal zero-displacement node of the transducer; and a second mounting point positioned at a proximal zero-displacement node of the transducer;
an end effector coupled to the transducer and extending distally along the longitudinal axis; and
a clamp pad coupled to the second operation member, wherein the clamp pad moves towards the end effector when the first operation member and the second operation member are pivoted towards one another about the pivot point.

2. The surgical instrument of claim 1, further comprising a first finger ring coupled to the first operation member at a point distal from the pivot point.

3. The surgical instrument of claim 2, wherein the first finger ring is rotatable about an axis perpendicular to the longitudinal axis.

4. The surgical instrument of claim 1, further comprising a support member positioned at the pivot point and configured to exert a torque on the first operation member and the second operation member, wherein the torque tends to pivot the first operation member and the second operation member away from one another.

5. The surgical instrument of claim 1, wherein the first operation member extends proximally from the pivot point and comprises a finger loop positioned proximally from the pivot point.

6. The surgical instrument of claim 5, wherein the first operation member is angled off of the longitudinal axis at a point positioned proximally from the pivot point.

7. A method for processing a surgical instrument for surgery, comprising:

obtaining the surgical instrument of claim 1;
sterilizing the surgical instrument; and
storing the surgical instrument in a sterile container.

8. The surgical instrument of claim 1, wherein the first operation member is pivotable towards the second operation member about the pivot point and the second operation member is pivotable towards the first operation member about the pivot point.

9. The surgical instrument of claim 1, wherein the end effector comprises a waveguide coupled to the transducer and a blade coupled to the waveguide.

10. The surgical instrument of claim 1, further comprising a port for receiving a wire to couple the transducer to a surgical generator.

11. The surgical instrument of claim 1, wherein the transducer comprises a gain stage, wherein the gain stage comprises at least one of the first metallic end mass or the second metallic end mass, and wherein at least a portion of the gain stage has a cross-sectional area different than a cross-sectional area of the piezoelectric stack.

12. The surgical instrument of claim 1, wherein the first mounting point comprises a flange and the second mounting point comprises a groove.

13. The surgical instrument of claim 1, wherein the first mounting point comprises a groove and the second mounting point comprises a flange.

14. The surgical instrument of claim 1, wherein the first mounting point comprises a groove and the second mounting point comprises a groove.

15. The surgical instrument of claim 1, wherein the first mounting point comprises a flange and the second mounting point comprises a flange.

16. The surgical instrument of claim 1, wherein at least one of the first mounting point or the second mounting point comprises a flange, wherein the transducer further comprises a second piezoelectric stack, and wherein the flange is positioned between the piezoelectric stack and the second piezoelectric stack.

17. A surgical instrument, comprising:

a first member, comprising: a transducer positioned along a longitudinal axis of the first member, wherein the transducer comprises: a piezoelectric stack positioned parallel to the longitudinal axis; a first metallic end mass positioned parallel to the longitudinal axis adjacent a first end of the piezoelectric stack; a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack, wherein a length of the transducer is greater than ½ of one wavelength; a first mounting point positioned at a distal zero-displacement node of the transducer; and a second mounting point positioned at a proximal zero-displacement node of the transducer; an end effector coupled to the transducer and extending distally along the longitudinal axis of the first member; and a first finger loop at a proximal portion of the first member, wherein the proximal portion of the first member is angled away from the longitudinal axis of the first member in a first direction;
a second member, comprising: a clamp pad positioned along a longitudinal axis of the second member at a distal portion of the second member opposite the end effector; and a second finger loop at a proximal portion of the second member, wherein the proximal portion of the second member is angled away from the longitudinal axis of the second member in the first direction; and
wherein the first member and the second member are pivotably coupled at a pivot point positioned distally from the first finger loop and the second finger loop, and wherein the end effector and the clamp pad are pivotable into contact with one another about the pivot point.

18. The surgical instrument of claim 17, wherein the first finger loop and the second finger loop are positioned parallel to a common plane.

19. The surgical instrument of claim 17, wherein the first finger loop is sized to fit more than one finger.

20. The surgical instrument of claim 17, wherein the second finger loop is sized to fit more than one finger.

21. The surgical instrument of claim 17, wherein the second member is pivotable towards the first member about the pivot point.

22. The surgical instrument of claim 17, wherein the first member is pivotable towards the second member about the pivot point.

Referenced Cited
U.S. Patent Documents
969528 September 1910 Disbrow
1570025 January 1926 Young
1813902 July 1931 Bovie
2704333 March 1955 Calosi et al.
2736960 March 1956 Armstrong
2849788 September 1958 Creek
2874470 February 1959 Richards
2990616 July 1961 Balamuth et al.
RE25033 August 1961 Balamuth et al.
3015961 January 1962 Roney
3053124 September 1962 Balamuth et al.
3082805 March 1963 Royce
3432691 March 1969 Shoh
3433226 March 1969 Boyd
3489930 January 1970 Shoh
3513848 May 1970 Winston et al.
3526219 September 1970 Balamuth
3554198 January 1971 Tatoian et al.
3614484 October 1971 Shoh
3616375 October 1971 Inoue
3629726 December 1971 Popescu
3636943 January 1972 Balamuth
3668486 June 1972 Silver
3702948 November 1972 Balamuth
3776238 December 1973 Peyman et al.
3805787 April 1974 Banko
3809977 May 1974 Balamuth et al.
3830098 August 1974 Antonevich
3854737 December 1974 Gilliam, Sr.
3862630 January 1975 Balamuth
3875945 April 1975 Friedman
3900823 August 1975 Sokal et al.
3918442 November 1975 Nikolaev et al.
3924335 December 1975 Balamuth et al.
3946738 March 30, 1976 Newton et al.
3955859 May 11, 1976 Stella et al.
3956826 May 18, 1976 Perdreaux, Jr.
4012647 March 15, 1977 Balamuth et al.
4074719 February 21, 1978 Semm
4156187 May 22, 1979 Murry et al.
4167944 September 18, 1979 Banko
4188927 February 19, 1980 Harris
4200106 April 29, 1980 Douvas et al.
4203444 May 20, 1980 Bonnell et al.
4300083 November 10, 1981 Heiges
4302728 November 24, 1981 Nakamura
4306570 December 22, 1981 Matthews
4445063 April 24, 1984 Smith
4491132 January 1, 1985 Aikins
4504264 March 12, 1985 Kelman
4512344 April 23, 1985 Barber
4526571 July 2, 1985 Wuchinich
4574615 March 11, 1986 Bower et al.
4617927 October 21, 1986 Manes
4633119 December 30, 1986 Thompson
4634420 January 6, 1987 Spinosa et al.
4640279 February 3, 1987 Beard
4641053 February 3, 1987 Takeda
4646738 March 3, 1987 Trott
4646756 March 3, 1987 Watmough et al.
4649919 March 17, 1987 Thimsen et al.
4662068 May 5, 1987 Polonsky
4674502 June 23, 1987 Imonti
4708127 November 24, 1987 Abdelghani
4712722 December 15, 1987 Hood et al.
4819635 April 11, 1989 Shapiro
4827911 May 9, 1989 Broadwin et al.
4832683 May 23, 1989 Idemoto et al.
4836186 June 6, 1989 Scholz
4838853 June 13, 1989 Parisi
4844064 July 4, 1989 Thimsen et al.
4850354 July 25, 1989 McGurk-Burleson et al.
4852578 August 1, 1989 Companion et al.
4865159 September 12, 1989 Jamison
4867157 September 19, 1989 McGurk-Burleson et al.
4878493 November 7, 1989 Pasternak et al.
4881550 November 21, 1989 Kothe
4896009 January 23, 1990 Pawlowski
4903696 February 27, 1990 Stasz et al.
4915643 April 10, 1990 Samejima et al.
4922902 May 8, 1990 Wuchinich et al.
4965532 October 23, 1990 Sakurai
4979952 December 25, 1990 Kubota et al.
4981756 January 1, 1991 Rhandhawa
5013956 May 7, 1991 Kurozumi et al.
5015227 May 14, 1991 Broadwin et al.
5026387 June 25, 1991 Thomas
5042707 August 27, 1991 Taheri
5084052 January 28, 1992 Jacobs
5105117 April 14, 1992 Yamaguchi
5109819 May 5, 1992 Custer et al.
5112300 May 12, 1992 Ureche
5123903 June 23, 1992 Quaid et al.
5126618 June 30, 1992 Takahashi et al.
D327872 July 14, 1992 McMills et al.
5162044 November 10, 1992 Gahn et al.
5163421 November 17, 1992 Bernstein et al.
5163537 November 17, 1992 Radev
5167725 December 1, 1992 Clark et al.
5174276 December 29, 1992 Crockard
D332660 January 19, 1993 Rawson et al.
5176677 January 5, 1993 Wuchinich
5176695 January 5, 1993 Dulebohn
5184605 February 9, 1993 Grezeszykowski
5188102 February 23, 1993 Idemoto et al.
D334173 March 23, 1993 Liu et al.
5209719 May 11, 1993 Baruch et al.
5213569 May 25, 1993 Davis
5214339 May 25, 1993 Naito
5218529 June 8, 1993 Meyer et al.
5221282 June 22, 1993 Wuchinich
5226909 July 13, 1993 Evans et al.
5226910 July 13, 1993 Kajiyama et al.
5241236 August 31, 1993 Sasaki et al.
5241968 September 7, 1993 Slater
5242460 September 7, 1993 Klein et al.
5254129 October 19, 1993 Alexander
5257988 November 2, 1993 L'Esperance, Jr.
5261922 November 16, 1993 Hood
5263957 November 23, 1993 Davison
5264925 November 23, 1993 Shipp et al.
5275166 January 4, 1994 Vaitekunas et al.
5275609 January 4, 1994 Pingleton et al.
5282800 February 1, 1994 Foshee et al.
5282817 February 1, 1994 Hoogeboom et al.
5285795 February 15, 1994 Ryan et al.
5304115 April 19, 1994 Pflueger et al.
D347474 May 31, 1994 Olson
5312023 May 17, 1994 Green et al.
5312425 May 17, 1994 Evans et al.
5322055 June 21, 1994 Davison et al.
5324299 June 28, 1994 Davison et al.
5326013 July 5, 1994 Green et al.
5326342 July 5, 1994 Pflueger et al.
5344420 September 6, 1994 Hilal et al.
5345937 September 13, 1994 Middleman et al.
5346502 September 13, 1994 Estabrook et al.
5353474 October 11, 1994 Good et al.
5357164 October 18, 1994 Imabayashi et al.
5357423 October 18, 1994 Weaver et al.
5359994 November 1, 1994 Krauter et al.
5366466 November 22, 1994 Christian et al.
5371429 December 6, 1994 Manna
5374813 December 20, 1994 Shipp
D354564 January 17, 1995 Medema
5381067 January 10, 1995 Greenstein et al.
5387215 February 7, 1995 Fisher
5389098 February 14, 1995 Tsuruta et al.
5394187 February 28, 1995 Shipp
5403312 April 4, 1995 Yates et al.
5403334 April 4, 1995 Evans et al.
5408268 April 18, 1995 Shipp
D358887 May 30, 1995 Feinberg
5411481 May 2, 1995 Allen et al.
5419761 May 30, 1995 Narayanan et al.
5421829 June 6, 1995 Olichney et al.
5423844 June 13, 1995 Miller
5438997 August 8, 1995 Sieben et al.
5445639 August 29, 1995 Kuslich et al.
5449370 September 12, 1995 Vaitekunas
5451220 September 19, 1995 Ciervo
5456684 October 10, 1995 Schmidt et al.
5471988 December 5, 1995 Fujio et al.
5478003 December 26, 1995 Green et al.
5483501 January 9, 1996 Park et al.
5486162 January 23, 1996 Brumbach
5490860 February 13, 1996 Middle et al.
5500216 March 19, 1996 Julian et al.
5501654 March 26, 1996 Failla et al.
5505693 April 9, 1996 Mackool
5507738 April 16, 1996 Ciervo
5527331 June 18, 1996 Kresch et al.
5540693 July 30, 1996 Fisher
5558671 September 24, 1996 Yates
5562609 October 8, 1996 Brumbach
5562610 October 8, 1996 Brumbach
5573424 November 12, 1996 Poppe
5577654 November 26, 1996 Bishop
5591187 January 7, 1997 Dekel
5593414 January 14, 1997 Shipp et al.
5601601 February 11, 1997 Tal et al.
5603773 February 18, 1997 Campbell
5607436 March 4, 1997 Pratt et al.
5618304 April 8, 1997 Hart et al.
5618492 April 8, 1997 Auten et al.
5620447 April 15, 1997 Smith et al.
5626595 May 6, 1997 Sklar et al.
5628760 May 13, 1997 Knoepfler
5630420 May 20, 1997 Vaitekunas
D381077 July 15, 1997 Hunt
5651780 July 29, 1997 Jackson et al.
5653713 August 5, 1997 Michelson
5669922 September 23, 1997 Hood
5674235 October 7, 1997 Parisi
5678568 October 21, 1997 Uchikubo et al.
5690269 November 25, 1997 Bolanos et al.
5694936 December 9, 1997 Fujimoto et al.
5704534 January 6, 1998 Huitema et al.
5711472 January 27, 1998 Bryan
5713896 February 3, 1998 Nardella
5717306 February 10, 1998 Shipp
5728130 March 17, 1998 Ishikawa et al.
5730752 March 24, 1998 Alden et al.
5733074 March 31, 1998 Stöck et al.
5741226 April 21, 1998 Strukel et al.
5766164 June 16, 1998 Mueller et al.
5792135 August 11, 1998 Madhani et al.
5792138 August 11, 1998 Shipp
5792165 August 11, 1998 Klieman et al.
5808396 September 15, 1998 Boukhny
5810859 September 22, 1998 DiMatteo et al.
5817084 October 6, 1998 Jensen
5817119 October 6, 1998 Klieman et al.
5827323 October 27, 1998 Klieman et al.
5828160 October 27, 1998 Sugishita
5833696 November 10, 1998 Whitfield et al.
5836897 November 17, 1998 Sakurai et al.
5836957 November 17, 1998 Schulz et al.
5843109 December 1, 1998 Mehta et al.
5851212 December 22, 1998 Zirps et al.
5858018 January 12, 1999 Shipp et al.
5873873 February 23, 1999 Smith et al.
5873882 February 23, 1999 Straub et al.
5878193 March 2, 1999 Wang et al.
5879364 March 9, 1999 Bromfield et al.
5883615 March 16, 1999 Fago et al.
5893835 April 13, 1999 Witt et al.
5897523 April 27, 1999 Wright et al.
5897569 April 27, 1999 Kellogg et al.
5904681 May 18, 1999 West, Jr.
5906627 May 25, 1999 Spaulding
5906628 May 25, 1999 Miyawaki et al.
5911699 June 15, 1999 Anis et al.
5916229 June 29, 1999 Evans
5935143 August 10, 1999 Hood
5935144 August 10, 1999 Estabrook
5938633 August 17, 1999 Beaupre
5944718 August 31, 1999 Austin et al.
5944737 August 31, 1999 Tsonton et al.
5947984 September 7, 1999 Whipple
5954736 September 21, 1999 Bishop et al.
5954746 September 21, 1999 Holthaus et al.
5957882 September 28, 1999 Nita et al.
5957943 September 28, 1999 Vaitekunas
5968007 October 19, 1999 Simon et al.
5968060 October 19, 1999 Kellogg
5974342 October 26, 1999 Petrofsky
D416089 November 2, 1999 Barton et al.
5980510 November 9, 1999 Tsonton et al.
5980546 November 9, 1999 Hood
5989274 November 23, 1999 Davison et al.
5989275 November 23, 1999 Estabrook et al.
5993465 November 30, 1999 Shipp et al.
5993972 November 30, 1999 Reich et al.
5994855 November 30, 1999 Lundell et al.
6024741 February 15, 2000 Williamson, IV et al.
6024750 February 15, 2000 Mastri et al.
6027515 February 22, 2000 Cimino
6031526 February 29, 2000 Shipp
6033375 March 7, 2000 Brumbach
6033399 March 7, 2000 Gines
6036667 March 14, 2000 Manna et al.
6036707 March 14, 2000 Spaulding
6048224 April 11, 2000 Kay
6050943 April 18, 2000 Slayton et al.
6051010 April 18, 2000 DiMatteo et al.
6056735 May 2, 2000 Okada et al.
6063098 May 16, 2000 Houser et al.
6066132 May 23, 2000 Chen et al.
6066151 May 23, 2000 Miyawaki et al.
6068627 May 30, 2000 Orszulak et al.
6068647 May 30, 2000 Witt et al.
6077285 June 20, 2000 Boukhny
6083191 July 4, 2000 Rose
6086584 July 11, 2000 Miller
6090120 July 18, 2000 Wright et al.
6096033 August 1, 2000 Tu et al.
6099542 August 8, 2000 Cohn et al.
6109500 August 29, 2000 Alli et al.
6110127 August 29, 2000 Suzuki
6113594 September 5, 2000 Savage
6117152 September 12, 2000 Huitema
6126629 October 3, 2000 Perkins
6129735 October 10, 2000 Okada et al.
6132368 October 17, 2000 Cooper
6132448 October 17, 2000 Perez et al.
6139320 October 31, 2000 Hahn
6139561 October 31, 2000 Shibata et al.
6142615 November 7, 2000 Qiu et al.
6142994 November 7, 2000 Swanson et al.
6147560 November 14, 2000 Erhage et al.
6152902 November 28, 2000 Christian et al.
6159160 December 12, 2000 Hsei et al.
6159175 December 12, 2000 Strukel et al.
6162194 December 19, 2000 Shipp
6165150 December 26, 2000 Banko
6174310 January 16, 2001 Kirwan, Jr.
6179853 January 30, 2001 Sachse et al.
6183426 February 6, 2001 Akisada et al.
6204592 March 20, 2001 Hur
6205855 March 27, 2001 Pfeiffer
6206844 March 27, 2001 Reichel et al.
6210403 April 3, 2001 Klicek
6214023 April 10, 2001 Whipple et al.
6228080 May 8, 2001 Gines
6231565 May 15, 2001 Tovey et al.
6233476 May 15, 2001 Strommer et al.
6238366 May 29, 2001 Savage et al.
6245065 June 12, 2001 Panescu et al.
6252110 June 26, 2001 Uemura et al.
D444365 July 3, 2001 Bass et al.
D445092 July 17, 2001 Lee
D445764 July 31, 2001 Lee
6254623 July 3, 2001 Haibel, Jr. et al.
6257241 July 10, 2001 Wampler
6258034 July 10, 2001 Hanafy
6267761 July 31, 2001 Ryan
6270831 August 7, 2001 Kumar et al.
6273852 August 14, 2001 Lehe et al.
6274963 August 14, 2001 Estabrook et al.
6277115 August 21, 2001 Saadat
6278218 August 21, 2001 Madan et al.
6280407 August 28, 2001 Manna et al.
6283981 September 4, 2001 Beaupre
6287344 September 11, 2001 Wampler et al.
6290575 September 18, 2001 Shipp
6306157 October 23, 2001 Shchervinsky
6309400 October 30, 2001 Beaupre
6319221 November 20, 2001 Savage et al.
6325795 December 4, 2001 Lindemann et al.
6325799 December 4, 2001 Goble
6325811 December 4, 2001 Messerly
6328751 December 11, 2001 Beaupre
6338657 January 15, 2002 Harper et al.
6340352 January 22, 2002 Okada et al.
6350269 February 26, 2002 Shipp et al.
6352532 March 5, 2002 Kramer et al.
6364888 April 2, 2002 Niemeyer et al.
6379320 April 30, 2002 Lafon et al.
D457958 May 28, 2002 Dycus et al.
6383194 May 7, 2002 Pothula
6387109 May 14, 2002 Davison et al.
6388657 May 14, 2002 Natoli
6391042 May 21, 2002 Cimino
6398779 June 4, 2002 Buysse et al.
6402743 June 11, 2002 Orszulak et al.
6402748 June 11, 2002 Schoenman et al.
6405733 June 18, 2002 Fogarty et al.
6416486 July 9, 2002 Wampler
6423073 July 23, 2002 Bowman
6423082 July 23, 2002 Houser et al.
6428539 August 6, 2002 Baxter et al.
6432118 August 13, 2002 Messerly
6436114 August 20, 2002 Novak et al.
6436115 August 20, 2002 Beaupre
6440062 August 27, 2002 Ouchi
6443968 September 3, 2002 Holthaus et al.
6443969 September 3, 2002 Novak et al.
6449006 September 10, 2002 Shipp
6454781 September 24, 2002 Witt et al.
6454782 September 24, 2002 Schwemberger
6458142 October 1, 2002 Faller et al.
6480796 November 12, 2002 Wiener
6485490 November 26, 2002 Wampler et al.
6491708 December 10, 2002 Madan et al.
6497715 December 24, 2002 Satou
6500176 December 31, 2002 Truckai et al.
6500188 December 31, 2002 Harper et al.
6500312 December 31, 2002 Wedekamp
6506208 January 14, 2003 Hunt et al.
6511493 January 28, 2003 Moutafis et al.
6514267 February 4, 2003 Jewett
6524251 February 25, 2003 Rabiner et al.
6524316 February 25, 2003 Nicholson et al.
6527736 March 4, 2003 Attinger et al.
6533784 March 18, 2003 Truckai et al.
6537291 March 25, 2003 Friedman et al.
6543452 April 8, 2003 Lavigne
6543456 April 8, 2003 Freeman
6544260 April 8, 2003 Markel et al.
6558376 May 6, 2003 Bishop
6572563 June 3, 2003 Ouchi
6572632 June 3, 2003 Zisterer et al.
6575969 June 10, 2003 Rittman, III et al.
6582451 June 24, 2003 Marucci et al.
D477408 July 15, 2003 Bromley
6588277 July 8, 2003 Giordano et al.
6589200 July 8, 2003 Schwemberger et al.
6589239 July 8, 2003 Khandkar et al.
6607540 August 19, 2003 Shipp
6610059 August 26, 2003 West, Jr.
6616450 September 9, 2003 Mossle et al.
6619529 September 16, 2003 Green et al.
6623500 September 23, 2003 Cook et al.
6623501 September 23, 2003 Heller et al.
6626848 September 30, 2003 Neuenfeldt
6626926 September 30, 2003 Friedman et al.
6633234 October 14, 2003 Wiener et al.
6644532 November 11, 2003 Green et al.
6652539 November 25, 2003 Shipp et al.
6652545 November 25, 2003 Shipp et al.
6656132 December 2, 2003 Ouchi
6656177 December 2, 2003 Truckai et al.
6660017 December 9, 2003 Beaupre
6662127 December 9, 2003 Wiener et al.
6663941 December 16, 2003 Brown et al.
6666860 December 23, 2003 Takahashi
6666875 December 23, 2003 Sakurai et al.
6669690 December 30, 2003 Okada et al.
6669710 December 30, 2003 Moutafis et al.
6676660 January 13, 2004 Wampler et al.
6678621 January 13, 2004 Wiener et al.
6679875 January 20, 2004 Honda et al.
6679899 January 20, 2004 Wiener et al.
6682544 January 27, 2004 Mastri et al.
6685701 February 3, 2004 Orszulak et al.
6685703 February 3, 2004 Pearson et al.
6689145 February 10, 2004 Lee et al.
6689146 February 10, 2004 Himes
6716215 April 6, 2004 David et al.
6719776 April 13, 2004 Baxter
D490059 May 18, 2004 Conway et al.
6731047 May 4, 2004 Kauf et al.
6733506 May 11, 2004 McDevitt et al.
6739872 May 25, 2004 Turri
D491666 June 15, 2004 Kimmell et al.
6743245 June 1, 2004 Lobdell
6746284 June 8, 2004 Spink, Jr.
6752815 June 22, 2004 Beaupre
6755825 June 29, 2004 Shoenman et al.
6761698 July 13, 2004 Shibata et al.
6762535 July 13, 2004 Take et al.
6770072 August 3, 2004 Truckai et al.
6773409 August 10, 2004 Truckai et al.
6773443 August 10, 2004 Truwit et al.
6773444 August 10, 2004 Messerly
6778023 August 17, 2004 Christensen
6783524 August 31, 2004 Anderson et al.
6786382 September 7, 2004 Hoffman
6786383 September 7, 2004 Stegelmann
6790173 September 14, 2004 Saadat et al.
6790216 September 14, 2004 Ishikawa
6796981 September 28, 2004 Wham et al.
D496997 October 5, 2004 Dycus et al.
6802843 October 12, 2004 Truckai et al.
6809508 October 26, 2004 Donofrio
6810281 October 26, 2004 Brock et al.
6827712 December 7, 2004 Tovey et al.
6828712 December 7, 2004 Battaglin et al.
6835082 December 28, 2004 Gonnering
6849073 February 1, 2005 Hoey et al.
6863676 March 8, 2005 Lee et al.
6869439 March 22, 2005 White et al.
6875220 April 5, 2005 Du et al.
6877647 April 12, 2005 Green et al.
6882439 April 19, 2005 Ishijima
6887209 May 3, 2005 Kadziauskas et al.
6887252 May 3, 2005 Okada et al.
6899685 May 31, 2005 Kermode et al.
6905497 June 14, 2005 Truckai et al.
6908472 June 21, 2005 Wiener et al.
6913579 July 5, 2005 Truckai et al.
6915623 July 12, 2005 Dey et al.
6923804 August 2, 2005 Eggers et al.
6926716 August 9, 2005 Baker et al.
6929632 August 16, 2005 Nita et al.
6929644 August 16, 2005 Truckai et al.
6933656 August 23, 2005 Matsushita et al.
D509589 September 13, 2005 Wells
6942660 September 13, 2005 Pantera et al.
6942677 September 13, 2005 Nita et al.
6945981 September 20, 2005 Donofrio et al.
6946779 September 20, 2005 Birgel
6948503 September 27, 2005 Refior et al.
D511145 November 1, 2005 Donofrio et al.
6974450 December 13, 2005 Weber et al.
6976844 December 20, 2005 Hickok et al.
6976969 December 20, 2005 Messerly
6977495 December 20, 2005 Donofrio
6979332 December 27, 2005 Adams
6981628 January 3, 2006 Wales
6984220 January 10, 2006 Wuchinich
6994708 February 7, 2006 Manzo
7001335 February 21, 2006 Adachi et al.
7011657 March 14, 2006 Truckai et al.
7014638 March 21, 2006 Michelson
7033357 April 25, 2006 Baxter et al.
7037306 May 2, 2006 Podany
7041083 May 9, 2006 Chu et al.
7041088 May 9, 2006 Nawrocki et al.
7041102 May 9, 2006 Truckai et al.
7044949 May 16, 2006 Orszulak et al.
7066893 June 27, 2006 Hibner et al.
7066895 June 27, 2006 Podany
7070597 July 4, 2006 Truckai et al.
7074218 July 11, 2006 Washington et al.
7074219 July 11, 2006 Levine et al.
7077039 July 18, 2006 Gass et al.
7077845 July 18, 2006 Hacker et al.
7077853 July 18, 2006 Kramer et al.
7083619 August 1, 2006 Truckai et al.
7087054 August 8, 2006 Truckai et al.
7090672 August 15, 2006 Underwood et al.
7101371 September 5, 2006 Dycus et al.
7101378 September 5, 2006 Salameh et al.
7104834 September 12, 2006 Robinson et al.
7108695 September 19, 2006 Witt et al.
7111769 September 26, 2006 Wales et al.
7112201 September 26, 2006 Truckai et al.
D531311 October 31, 2006 Guerra et al.
7117034 October 3, 2006 Kronberg
7118564 October 10, 2006 Ritchie et al.
7124932 October 24, 2006 Isaacson et al.
7125409 October 24, 2006 Truckai et al.
7128720 October 31, 2006 Podany
7131860 November 7, 2006 Sartor et al.
7135018 November 14, 2006 Ryan et al.
7135030 November 14, 2006 Schwemberger et al.
7137980 November 21, 2006 Buysse et al.
7144403 December 5, 2006 Booth
7153315 December 26, 2006 Miller
D536093 January 30, 2007 Nakajima et al.
7156189 January 2, 2007 Bar-Cohen et al.
7156853 January 2, 2007 Muratsu
7157058 January 2, 2007 Marhasin et al.
7159750 January 9, 2007 Racenet et al.
7160299 January 9, 2007 Baily
7163548 January 16, 2007 Stulen et al.
7169144 January 30, 2007 Hoey et al.
7169146 January 30, 2007 Truckai et al.
7179254 February 20, 2007 Pendekanti et al.
7179271 February 20, 2007 Friedman et al.
7186253 March 6, 2007 Truckai et al.
7189233 March 13, 2007 Truckai et al.
D541418 April 24, 2007 Schechter et al.
7204820 April 17, 2007 Akahoshi
7207997 April 24, 2007 Shipp et al.
7210881 May 1, 2007 Greenberg
7211079 May 1, 2007 Treat
7217128 May 15, 2007 Atkin et al.
7217269 May 15, 2007 El-Galley et al.
7220951 May 22, 2007 Truckai et al.
7223229 May 29, 2007 Inman et al.
7229455 June 12, 2007 Sakurai et al.
7235071 June 26, 2007 Gonnering
7244262 July 17, 2007 Wiener et al.
7269873 September 18, 2007 Brewer et al.
7273483 September 25, 2007 Wiener et al.
D552241 October 2, 2007 Bromley et al.
7282048 October 16, 2007 Goble et al.
7285895 October 23, 2007 Beaupré
7300431 November 27, 2007 Dubrovsky
7300435 November 27, 2007 Wham et al.
7300446 November 27, 2007 Beaupre
7303531 December 4, 2007 Lee et al.
7303557 December 4, 2007 Wham et al.
7309849 December 18, 2007 Truckai et al.
7311706 December 25, 2007 Schoenman et al.
7311709 December 25, 2007 Truckai et al.
7317955 January 8, 2008 McGreevy
7318831 January 15, 2008 Alvarez et al.
7326236 February 5, 2008 Andreas et al.
7331410 February 19, 2008 Yong et al.
7335165 February 26, 2008 Truwit et al.
7335997 February 26, 2008 Wiener
7337010 February 26, 2008 Howard et al.
7353068 April 1, 2008 Tanaka et al.
7354440 April 8, 2008 Truckai et al.
7364577 April 29, 2008 Wham et al.
RE40388 June 17, 2008 Gines
7380695 June 3, 2008 Doll et al.
7380696 June 3, 2008 Shelton, IV et al.
7381209 June 3, 2008 Truckai et al.
7390317 June 24, 2008 Taylor et al.
7404508 July 29, 2008 Smith et al.
7408288 August 5, 2008 Hara
7416101 August 26, 2008 Shelton, IV et al.
7416437 August 26, 2008 Sartor et al.
D576725 September 9, 2008 Shumer et al.
7419490 September 2, 2008 Falkenstein et al.
7422139 September 9, 2008 Shelton, IV et al.
7422463 September 9, 2008 Kuo
D578643 October 14, 2008 Shumer et al.
D578644 October 14, 2008 Shumer et al.
D578645 October 14, 2008 Shumer et al.
7431704 October 7, 2008 Babaev
7441684 October 28, 2008 Shelton, IV et al.
7455208 November 25, 2008 Wales et al.
7462181 December 9, 2008 Kraft et al.
7464846 December 16, 2008 Sheltion, IV et al.
7472815 January 6, 2009 Shelton, IV et al.
7473263 January 6, 2009 Johnston et al.
7479148 January 20, 2009 Beaupre
7479160 January 20, 2009 Branch et al.
7481775 January 27, 2009 Weikel, Jr. et al.
7488285 February 10, 2009 Honda et al.
7494468 February 24, 2009 Rabiner et al.
7503893 March 17, 2009 Kucklick
7503895 March 17, 2009 Rabiner et al.
7506790 March 24, 2009 Shelton, IV
7506791 March 24, 2009 Omaits et al.
7524320 April 28, 2009 Tierney et al.
7530986 May 12, 2009 Beaupre et al.
7534243 May 19, 2009 Chin et al.
D594983 June 23, 2009 Price et al.
7540871 June 2, 2009 Gonnering
7544200 June 9, 2009 Houser
7549564 June 23, 2009 Boudreaux
7559450 July 14, 2009 Wales et al.
7567012 July 28, 2009 Namikawa
7572266 August 11, 2009 Young et al.
7578820 August 25, 2009 Moore et al.
7582095 September 1, 2009 Shipp et al.
7585181 September 8, 2009 Olsen
7588176 September 15, 2009 Timm et al.
7601119 October 13, 2009 Shahinian
7621930 November 24, 2009 Houser
7641653 January 5, 2010 Dalla Betta et al.
7654431 February 2, 2010 Hueil et al.
7659833 February 9, 2010 Warner et al.
7665647 February 23, 2010 Shelton, IV et al.
7670334 March 2, 2010 Hueil et al.
7670338 March 2, 2010 Albrecht et al.
7674263 March 9, 2010 Ryan
7678069 March 16, 2010 Baker et al.
7678125 March 16, 2010 Shipp
7682366 March 23, 2010 Sakurai et al.
7686770 March 30, 2010 Cohen
7686826 March 30, 2010 Lee et al.
7688028 March 30, 2010 Phillips et al.
7691098 April 6, 2010 Wallace et al.
7699846 April 20, 2010 Ryan
7713202 May 11, 2010 Boukhny et al.
7714481 May 11, 2010 Sakai
D618797 June 29, 2010 Price et al.
7726537 June 1, 2010 Olson et al.
7738969 June 15, 2010 Bleich
7740594 June 22, 2010 Hibner
7751115 July 6, 2010 Song
D621503 August 10, 2010 Otten et al.
7766210 August 3, 2010 Shelton, IV et al.
7766693 August 3, 2010 Sartor et al.
7770774 August 10, 2010 Mastri et al.
7770775 August 10, 2010 Shelton, IV et al.
7771444 August 10, 2010 Patel et al.
7775972 August 17, 2010 Brock et al.
7778733 August 17, 2010 Nowlin et al.
7780054 August 24, 2010 Wales
7780593 August 24, 2010 Ueno et al.
7780651 August 24, 2010 Madhani et al.
7780659 August 24, 2010 Okada et al.
7784662 August 31, 2010 Wales et al.
7796969 September 14, 2010 Kelly et al.
7798386 September 21, 2010 Schall et al.
7799020 September 21, 2010 Shores et al.
7799045 September 21, 2010 Masuda
7803152 September 28, 2010 Honda et al.
7806891 October 5, 2010 Nowlin et al.
7810693 October 12, 2010 Broehl et al.
7819819 October 26, 2010 Quick et al.
D627066 November 9, 2010 Romero
7824401 November 2, 2010 Manzo et al.
7832611 November 16, 2010 Boyden et al.
7834484 November 16, 2010 Sartor
7837699 November 23, 2010 Yamada et al.
7845537 December 7, 2010 Shelton, IV et al.
7846155 December 7, 2010 Houser et al.
7846161 December 7, 2010 Dumbauld et al.
7854735 December 21, 2010 Houser et al.
D631155 January 18, 2011 Peine et al.
7861906 January 4, 2011 Doll et al.
7862560 January 4, 2011 Marion
7876030 January 25, 2011 Taki et al.
D631965 February 1, 2011 Price et al.
7878991 February 1, 2011 Babaev
7879033 February 1, 2011 Sartor et al.
7892606 February 22, 2011 Thies et al.
7901400 March 8, 2011 Wham et al.
7901423 March 8, 2011 Stulen et al.
7905881 March 15, 2011 Masuda et al.
7922061 April 12, 2011 Shelton, IV et al.
7922651 April 12, 2011 Yamada et al.
D637288 May 3, 2011 Houghton
D638540 May 24, 2011 Ijiri et al.
7951165 May 31, 2011 Golden et al.
7959050 June 14, 2011 Smith et al.
7959626 June 14, 2011 Hong et al.
7972329 July 5, 2011 Refior et al.
7976544 July 12, 2011 McClurken et al.
7981050 July 19, 2011 Ritchart et al.
7998157 August 16, 2011 Culp et al.
8038693 October 18, 2011 Allen
8057498 November 15, 2011 Robertson
8058771 November 15, 2011 Giordano et al.
8061014 November 22, 2011 Smith et al.
8070711 December 6, 2011 Bassinger et al.
8070762 December 6, 2011 Escudero et al.
8075558 December 13, 2011 Truckai et al.
8089197 January 3, 2012 Rinner et al.
8097012 January 17, 2012 Kagarise
8105323 January 31, 2012 Buysse et al.
8142461 March 27, 2012 Houser et al.
8152825 April 10, 2012 Madan et al.
8157145 April 17, 2012 Shelton, IV et al.
8161977 April 24, 2012 Shelton, IV et al.
8162966 April 24, 2012 Connor et al.
8172846 May 8, 2012 Brunnett et al.
8172870 May 8, 2012 Shipp
8177800 May 15, 2012 Spitz et al.
8182502 May 22, 2012 Stulen et al.
D661801 June 12, 2012 Price et al.
D661802 June 12, 2012 Price et al.
D661803 June 12, 2012 Price et al.
D661804 June 12, 2012 Price et al.
8197502 June 12, 2012 Smith et al.
8226675 July 24, 2012 Houser et al.
8236019 August 7, 2012 Houser
8236020 August 7, 2012 Smith et al.
8246575 August 21, 2012 Viola
8246615 August 21, 2012 Behnke
8252012 August 28, 2012 Stulen
8253303 August 28, 2012 Giordano et al.
8257377 September 4, 2012 Wiener et al.
8257387 September 4, 2012 Cunningham
8273087 September 25, 2012 Kimura et al.
D669992 October 30, 2012 Schafer et al.
D669993 October 30, 2012 Merchant et al.
8286846 October 16, 2012 Smith et al.
8287485 October 16, 2012 Kimura et al.
8287528 October 16, 2012 Wham et al.
8287532 October 16, 2012 Carroll et al.
8303576 November 6, 2012 Brock
8319400 November 27, 2012 Houser et al.
8323302 December 4, 2012 Robertson et al.
8333778 December 18, 2012 Smith et al.
8333779 December 18, 2012 Smith et al.
8334468 December 18, 2012 Palmer et al.
8334635 December 18, 2012 Voegele et al.
8337407 December 25, 2012 Quistgaard et al.
8338726 December 25, 2012 Palmer et al.
8344596 January 1, 2013 Nield et al.
8348967 January 8, 2013 Stulen
8357103 January 22, 2013 Mark et al.
8372099 February 12, 2013 Deville et al.
8372101 February 12, 2013 Smith et al.
8372102 February 12, 2013 Stulen et al.
8374670 February 12, 2013 Selkee
8377059 February 19, 2013 Deville et al.
8377085 February 19, 2013 Smith et al.
8382782 February 26, 2013 Robertson et al.
8403948 March 26, 2013 Deville et al.
8403949 March 26, 2013 Palmer et al.
8403950 March 26, 2013 Palmer et al.
8418349 April 16, 2013 Smith et al.
8419757 April 16, 2013 Smith et al.
8419758 April 16, 2013 Smith et al.
8419759 April 16, 2013 Dietz
8425545 April 23, 2013 Smith et al.
8430898 April 30, 2013 Wiener et al.
8435257 May 7, 2013 Smith et al.
8439912 May 14, 2013 Cunningham et al.
8439939 May 14, 2013 Deville et al.
8444637 May 21, 2013 Podmore et al.
8444662 May 21, 2013 Palmer et al.
8461744 June 11, 2013 Wiener et al.
8469981 June 25, 2013 Robertson et al.
8479969 July 9, 2013 Shelton, IV
8485413 July 16, 2013 Scheib et al.
8486057 July 16, 2013 Behnke, II
8486096 July 16, 2013 Robertson et al.
8491578 July 23, 2013 Manwaring et al.
D687549 August 6, 2013 Johnson et al.
8512365 August 20, 2013 Wiener et al.
8523889 September 3, 2013 Stulen et al.
8531064 September 10, 2013 Robertson et al.
8535340 September 17, 2013 Allen
8535341 September 17, 2013 Allen
8546996 October 1, 2013 Messerly et al.
8546999 October 1, 2013 Houser et al.
8573461 November 5, 2013 Shelton, IV et al.
8573465 November 5, 2013 Shelton, IV
8579928 November 12, 2013 Robertson et al.
8591506 November 26, 2013 Wham et al.
8591536 November 26, 2013 Robertson
D695407 December 10, 2013 Price et al.
D696631 December 31, 2013 Price et al.
8602288 December 10, 2013 Shelton, IV et al.
8616431 December 31, 2013 Timm et al.
8623027 January 7, 2014 Price et al.
8650728 February 18, 2014 Wan et al.
8652155 February 18, 2014 Houser et al.
8659208 February 25, 2014 Rose et al.
8663220 March 4, 2014 Wiener et al.
8690582 April 8, 2014 Rohrbach et al.
8696366 April 15, 2014 Chen et al.
8704425 April 22, 2014 Giordano et al.
8709031 April 29, 2014 Stulen
8749116 June 10, 2014 Messerly et al.
8754570 June 17, 2014 Voegele et al.
8764735 July 1, 2014 Coe et al.
8773001 July 8, 2014 Wiener et al.
8779648 July 15, 2014 Giordano et al.
20010025173 September 27, 2001 Ritchie et al.
20010025183 September 27, 2001 Shahidi et al.
20010025184 September 27, 2001 Messerly
20010031950 October 18, 2001 Ryan
20010039419 November 8, 2001 Francischelli et al.
20020002377 January 3, 2002 Cimino
20020019649 February 14, 2002 Sikora et al.
20020022836 February 21, 2002 Goble et al.
20020029055 March 7, 2002 Bonutti
20020049551 April 25, 2002 Friedman et al.
20020052617 May 2, 2002 Anis et al.
20020077550 June 20, 2002 Rabiner et al.
20020103438 August 1, 2002 Cronin et al.
20020120267 August 29, 2002 Phan
20020156466 October 24, 2002 Sakurai et al.
20020156493 October 24, 2002 Houser et al.
20030014087 January 16, 2003 Fang et al.
20030036705 February 20, 2003 Hare et al.
20030050572 March 13, 2003 Brautigam et al.
20030055443 March 20, 2003 Spotnitz
20030114851 June 19, 2003 Truckai et al.
20030144680 July 31, 2003 Kellogg et al.
20030199794 October 23, 2003 Sakurai et al.
20030204199 October 30, 2003 Novak et al.
20030212332 November 13, 2003 Fenton et al.
20030212363 November 13, 2003 Shipp
20030212422 November 13, 2003 Fenton et al.
20030229344 December 11, 2003 Dycus et al.
20040030254 February 12, 2004 Babaev
20040030330 February 12, 2004 Brassell et al.
20040047485 March 11, 2004 Sherrit et al.
20040054364 March 18, 2004 Aranyi et al.
20040064151 April 1, 2004 Mollenauer
20040092921 May 13, 2004 Kadziauskas et al.
20040092992 May 13, 2004 Adams et al.
20040097912 May 20, 2004 Gonnering
20040097919 May 20, 2004 Wellman et al.
20040097996 May 20, 2004 Rabiner et al.
20040116952 June 17, 2004 Sakurai et al.
20040147934 July 29, 2004 Kiester
20040167508 August 26, 2004 Wham et al.
20040176686 September 9, 2004 Hare et al.
20040199193 October 7, 2004 Hayashi et al.
20040204728 October 14, 2004 Haefner
20040243147 December 2, 2004 Lipow
20040260300 December 23, 2004 Gorensek et al.
20050021018 January 27, 2005 Anderson et al.
20050021065 January 27, 2005 Yamada et al.
20050033337 February 10, 2005 Muir et al.
20050049546 March 3, 2005 Messerly et al.
20050070800 March 31, 2005 Takahashi
20050096683 May 5, 2005 Ellins et al.
20050099824 May 12, 2005 Dowling et al.
20050103819 May 19, 2005 Racenet et al.
20050143769 June 30, 2005 White et al.
20050149108 July 7, 2005 Cox
20050165345 July 28, 2005 Laufer et al.
20050177184 August 11, 2005 Easley
20050182339 August 18, 2005 Lee et al.
20050188743 September 1, 2005 Land
20050192610 September 1, 2005 Houser et al.
20050209620 September 22, 2005 Du et al.
20050234484 October 20, 2005 Houser et al.
20050249667 November 10, 2005 Tuszynski et al.
20050256405 November 17, 2005 Makin et al.
20050261581 November 24, 2005 Hughes et al.
20050261588 November 24, 2005 Makin et al.
20050273090 December 8, 2005 Nieman et al.
20050288659 December 29, 2005 Kimura et al.
20060030797 February 9, 2006 Zhou et al.
20060058825 March 16, 2006 Ogura et al.
20060063130 March 23, 2006 Hayman et al.
20060066181 March 30, 2006 Bromfield et al.
20060079879 April 13, 2006 Faller et al.
20060084963 April 20, 2006 Messerly
20060095046 May 4, 2006 Trieu et al.
20060122592 June 8, 2006 Treat
20060190034 August 24, 2006 Nishizawa et al.
20060206100 September 14, 2006 Eskridge et al.
20060206115 September 14, 2006 Schomer et al.
20060211943 September 21, 2006 Beaupre
20060217729 September 28, 2006 Eskridge et al.
20060235306 October 19, 2006 Cotter et al.
20060241471 October 26, 2006 Beaupre′
20060253050 November 9, 2006 Yoshimine et al.
20060264809 November 23, 2006 Hansmann et al.
20070016235 January 18, 2007 Tanaka et al.
20070016236 January 18, 2007 Beaupre
20070055228 March 8, 2007 Berg et al.
20070056596 March 15, 2007 Fanney et al.
20070060915 March 15, 2007 Kucklick
20070060935 March 15, 2007 Schwardt et al.
20070063618 March 22, 2007 Bromfield
20070074584 April 5, 2007 Talarico et al.
20070106317 May 10, 2007 Shelton, IV et al.
20070129716 June 7, 2007 Daw et al.
20070130771 June 14, 2007 Ehlert et al.
20070131034 June 14, 2007 Ehlert et al.
20070149881 June 28, 2007 Rabin
20070162050 July 12, 2007 Sartor
20070166663 July 19, 2007 Telles et al.
20070173803 July 26, 2007 Wham et al.
20070173813 July 26, 2007 Odom
20070173872 July 26, 2007 Neuenfeldt
20070175949 August 2, 2007 Shelton, IV et al.
20070185380 August 9, 2007 Kucklick
20070191712 August 16, 2007 Messerly et al.
20070219481 September 20, 2007 Babaev
20070239028 October 11, 2007 Houser et al.
20070239101 October 11, 2007 Kellogg
20070249941 October 25, 2007 Salehi et al.
20070260234 November 8, 2007 McCullagh et al.
20070265560 November 15, 2007 Soltani et al.
20070275348 November 29, 2007 Lemon
20070282335 December 6, 2007 Young et al.
20070287933 December 13, 2007 Phan et al.
20080009848 January 10, 2008 Paraschiv et al.
20080051812 February 28, 2008 Schmitz et al.
20080058585 March 6, 2008 Novak et al.
20080058775 March 6, 2008 Darian et al.
20080058845 March 6, 2008 Shimizu et al.
20080082039 April 3, 2008 Babaev
20080082098 April 3, 2008 Tanaka et al.
20080114364 May 15, 2008 Goldin et al.
20080125768 May 29, 2008 Tahara et al.
20080140158 June 12, 2008 Hamel et al.
20080171938 July 17, 2008 Masuda et al.
20080172051 July 17, 2008 Masuda et al.
20080177268 July 24, 2008 Daum et al.
20080188878 August 7, 2008 Young
20080200940 August 21, 2008 Eichmann et al.
20080208231 August 28, 2008 Ota et al.
20080214967 September 4, 2008 Aranyi et al.
20080234709 September 25, 2008 Houser
20080234710 September 25, 2008 Neurohr et al.
20080243106 October 2, 2008 Coe et al.
20080245371 October 9, 2008 Gruber
20080249553 October 9, 2008 Gruber et al.
20080255423 October 16, 2008 Kondo et al.
20080262490 October 23, 2008 Williams
20080281200 November 13, 2008 Voic et al.
20080281315 November 13, 2008 Gines
20080281322 November 13, 2008 Sherman et al.
20080287948 November 20, 2008 Newton et al.
20090023985 January 22, 2009 Ewers
20090030437 January 29, 2009 Houser et al.
20090030439 January 29, 2009 Stulen
20090036914 February 5, 2009 Houser
20090048537 February 19, 2009 Lydon et al.
20090054886 February 26, 2009 Yachi et al.
20090054894 February 26, 2009 Yachi
20090076506 March 19, 2009 Baker
20090082716 March 26, 2009 Akahoshi
20090112229 April 30, 2009 Omori et al.
20090118751 May 7, 2009 Wiener et al.
20090118802 May 7, 2009 Mioduski et al.
20090138006 May 28, 2009 Bales et al.
20090143799 June 4, 2009 Smith et al.
20090143800 June 4, 2009 Deville et al.
20090143806 June 4, 2009 Witt et al.
20090149801 June 11, 2009 Crandall et al.
20090207923 August 20, 2009 Dress
20090223033 September 10, 2009 Houser
20090254077 October 8, 2009 Craig
20090270853 October 29, 2009 Yachi et al.
20090270899 October 29, 2009 Carusillo et al.
20090275940 November 5, 2009 Malackowski et al.
20090318945 December 24, 2009 Yoshimine et al.
20090327715 December 31, 2009 Smith et al.
20100004508 January 7, 2010 Naito et al.
20100016785 January 21, 2010 Takuma
20100016852 January 21, 2010 Manzo et al.
20100022825 January 28, 2010 Yoshie
20100030233 February 4, 2010 Whitman et al.
20100030248 February 4, 2010 Palmer et al.
20100036370 February 11, 2010 Mirel et al.
20100042077 February 18, 2010 Okada
20100049180 February 25, 2010 Wells et al.
20100069940 March 18, 2010 Miller et al.
20100158307 June 24, 2010 Kubota et al.
20100187283 July 29, 2010 Crainich et al.
20100222714 September 2, 2010 Muir et al.
20100228264 September 9, 2010 Robinson et al.
20100234906 September 16, 2010 Koh
20100262134 October 14, 2010 Jensen et al.
20100274160 October 28, 2010 Yachi et al.
20100280407 November 4, 2010 Polster
20100292691 November 18, 2010 Brogna
20100298743 November 25, 2010 Nield et al.
20100298851 November 25, 2010 Nield
20110004233 January 6, 2011 Muir et al.
20110009850 January 13, 2011 Main et al.
20110015627 January 20, 2011 DiNardo et al.
20110077648 March 31, 2011 Lee et al.
20110082486 April 7, 2011 Messerly et al.
20110087212 April 14, 2011 Aldridge et al.
20110087213 April 14, 2011 Messerly et al.
20110087214 April 14, 2011 Giordano et al.
20110087215 April 14, 2011 Aldridge et al.
20110087216 April 14, 2011 Aldridge et al.
20110087217 April 14, 2011 Yates et al.
20110087218 April 14, 2011 Boudreaux et al.
20110087256 April 14, 2011 Wiener et al.
20110112526 May 12, 2011 Fritz et al.
20110144806 June 16, 2011 Sandhu et al.
20110196398 August 11, 2011 Robertson et al.
20110196399 August 11, 2011 Robertson et al.
20110196404 August 11, 2011 Dietz et al.
20110224689 September 15, 2011 Larkin et al.
20110238065 September 29, 2011 Hunt et al.
20110257650 October 20, 2011 Deville et al.
20110270126 November 3, 2011 Gunday et al.
20110290853 December 1, 2011 Shelton, IV et al.
20110290856 December 1, 2011 Shelton, IV et al.
20120004655 January 5, 2012 Kim et al.
20120022525 January 26, 2012 Dietz et al.
20120022530 January 26, 2012 Woodruff et al.
20120059289 March 8, 2012 Nield et al.
20120065628 March 15, 2012 Naito
20120071863 March 22, 2012 Lee et al.
20120078139 March 29, 2012 Aldridge et al.
20120078243 March 29, 2012 Worrell et al.
20120078244 March 29, 2012 Worrell et al.
20120078247 March 29, 2012 Worrell et al.
20120078278 March 29, 2012 Bales, Jr. et al.
20120080332 April 5, 2012 Shelton, IV et al.
20120083783 April 5, 2012 Davison et al.
20120083784 April 5, 2012 Davison et al.
20120116379 May 10, 2012 Yates et al.
20120116391 May 10, 2012 Houser et al.
20120116394 May 10, 2012 Timm et al.
20120116395 May 10, 2012 Madan et al.
20120130256 May 24, 2012 Buysse et al.
20120130365 May 24, 2012 McLawhorn
20120136354 May 31, 2012 Rupp
20120138660 June 7, 2012 Shelton, IV
20120143211 June 7, 2012 Kishi
20120150170 June 14, 2012 Buysse et al.
20120165816 June 28, 2012 Kersten et al.
20120172873 July 5, 2012 Artale et al.
20120172904 July 5, 2012 Muir et al.
20120177005 July 12, 2012 Liang et al.
20120184946 July 19, 2012 Price et al.
20120199630 August 9, 2012 Shelton, IV
20120199632 August 9, 2012 Spivey et al.
20120203247 August 9, 2012 Shelton, IV et al.
20120209289 August 16, 2012 Duque et al.
20120209303 August 16, 2012 Frankhouser et al.
20120210223 August 16, 2012 Eppolito
20120245582 September 27, 2012 Kimball et al.
20120259353 October 11, 2012 Houser et al.
20120265196 October 18, 2012 Turner et al.
20120269676 October 25, 2012 Houser et al.
20120310262 December 6, 2012 Messerly et al.
20120330307 December 27, 2012 Ladtkow et al.
20130012957 January 10, 2013 Shelton, IV et al.
20130012970 January 10, 2013 Houser
20130030433 January 31, 2013 Heard
20130035680 February 7, 2013 Ben-Haim et al.
20130053840 February 28, 2013 Krapohl et al.
20130072856 March 21, 2013 Frankhouser et al.
20130072857 March 21, 2013 Frankhouser et al.
20130079762 March 28, 2013 Twomey et al.
20130103023 April 25, 2013 Monson et al.
20130103024 April 25, 2013 Monson et al.
20130110145 May 2, 2013 Weitzman
20130123776 May 16, 2013 Monson et al.
20130123777 May 16, 2013 Monson et al.
20130123782 May 16, 2013 Trees et al.
20130123822 May 16, 2013 Wellman et al.
20130131660 May 23, 2013 Monson et al.
20130165929 June 27, 2013 Muir et al.
20130211397 August 15, 2013 Parihar et al.
20130217967 August 22, 2013 Mohr et al.
20130226207 August 29, 2013 Stulen et al.
20130245659 September 19, 2013 Robertson et al.
20130267975 October 10, 2013 Timm et al.
20130274734 October 17, 2013 Maass et al.
20130282003 October 24, 2013 Messerly et al.
20130282039 October 24, 2013 Wiener et al.
20130285758 October 31, 2013 Aldridge et al.
20130289591 October 31, 2013 Boudreaux et al.
20130296908 November 7, 2013 Schulte et al.
20130338661 December 19, 2013 Behnke, II
20130345689 December 26, 2013 Ruddenklau et al.
20130345733 December 26, 2013 Robertson et al.
20140005640 January 2, 2014 Shelton, IV et al.
20140005653 January 2, 2014 Shelton, IV et al.
20140005654 January 2, 2014 Batross et al.
20140005656 January 2, 2014 Mucilli et al.
20140005661 January 2, 2014 Shelton, IV et al.
20140005662 January 2, 2014 Shelton, IV et al.
20140005667 January 2, 2014 Stulen et al.
20140005668 January 2, 2014 Rhee et al.
20140005676 January 2, 2014 Shelton, IV et al.
20140005680 January 2, 2014 Shelton, IV et al.
20140005681 January 2, 2014 Gee et al.
20140005682 January 2, 2014 Worrell et al.
20140005701 January 2, 2014 Olson et al.
20140005702 January 2, 2014 Timm et al.
20140005703 January 2, 2014 Stulen et al.
20140005704 January 2, 2014 Vakharia et al.
20140005705 January 2, 2014 Weir et al.
20140005708 January 2, 2014 Shelton, IV et al.
20140005718 January 2, 2014 Shelton, IV et al.
20140058427 February 27, 2014 Robertson
20140066962 March 6, 2014 Robertson et al.
20140087569 March 27, 2014 Lee
20140114327 April 24, 2014 Boudreaux et al.
20140114334 April 24, 2014 Olson et al.
20140155921 June 5, 2014 Price et al.
20140180280 June 26, 2014 Sigmon, Jr.
Foreign Patent Documents
2003241752 September 2003 AU
1634601 July 2005 CN
1640365 July 2005 CN
1694649 November 2005 CN
1922563 February 2007 CN
1951333 April 2007 CN
101040799 September 2007 CN
101467917 January 2009 CN
9210327 November 1992 DE
4323585 January 1995 DE
19608716 April 1997 DE
20021619 March 2001 DE
10042606 August 2001 DE
0171967 February 1986 EP
1839599 October 1987 EP
0443256 August 1991 EP
0456470 November 1991 EP
0598976 January 1994 EP
0677275 March 1995 EP
0482195 January 1996 EP
0695535 February 1996 EP
0741996 November 1996 EP
0612570 June 1997 EP
1108394 June 2001 EP
0908148 January 2002 EP
1229515 August 2002 EP
1285634 February 2003 EP
0908155 June 2003 EP
0705570 April 2004 EP
0765637 July 2004 EP
0870473 September 2005 EP
0624346 November 2005 EP
1594209 November 2005 EP
1199044 December 2005 EP
1609428 December 2005 EP
1199043 March 2006 EP
1433425 June 2006 EP
1704824 September 2006 EP
1749479 February 2007 EP
1815950 August 2007 EP
1844720 October 2007 EP
1862133 December 2007 EP
1199045 June 2008 EP
1972264 September 2008 EP
1974771 October 2008 EP
1435852 December 2008 EP
1498082 December 2008 EP
1707131 December 2008 EP
1997438 December 2008 EP
1477104 January 2009 EP
2014218 January 2009 EP
2042112 April 2009 EP
1832259 June 2009 EP
2074959 July 2009 EP
2111813 October 2009 EP
2200145 June 2010 EP
1214913 July 2010 EP
2238938 October 2010 EP
2298154 March 2011 EP
1510178 June 2011 EP
2305144 June 2011 EP
2335630 June 2011 EP
1502551 July 2011 EP
2361562 August 2011 EP
2365608 September 2011 EP
2316359 March 2013 EP
1586275 May 2013 EP
1616529 September 2013 EP
2032221 April 1980 GB
2379878 November 2004 GB
2447767 August 2011 GB
S 50-100891 December 1973 JP
S 59-68513 October 1982 JP
62-221343 September 1987 JP
S 62-227343 October 1987 JP
62-292153 December 1987 JP
63-109386 May 1988 JP
63-315049 December 1988 JP
H 01-151452 June 1989 JP
H 01-198540 August 1989 JP
02-71510 May 1990 JP
H 02-292193 December 1990 JP
04-25707 February 1992 JP
4-30508 March 1992 JP
05-095955 April 1993 JP
H 06-070938 March 1994 JP
6-104503 April 1994 JP
6-507081 August 1994 JP
H 7-508910 October 1995 JP
7-308323 November 1995 JP
8-24266 January 1996 JP
8-275951 October 1996 JP
H 08-336545 December 1996 JP
H 09-503146 March 1997 JP
H 09-135553 May 1997 JP
10-295700 November 1998 JP
H 11-501543 February 1999 JP
H 11-128238 May 1999 JP
H 11-192235 July 1999 JP
11-253451 September 1999 JP
2000-041991 February 2000 JP
2000-070279 March 2000 JP
2000-210299 August 2000 JP
2000-287987 October 2000 JP
2001-502216 February 2001 JP
2003612 June 2001 JP
2001-309925 November 2001 JP
2002-186901 July 2002 JP
2002-204808 July 2002 JP
2002-263579 September 2002 JP
2002-330977 November 2002 JP
2002-542690 December 2002 JP
2003-000612 January 2003 JP
2003-010201 January 2003 JP
2003-510158 March 2003 JP
2003-126110 May 2003 JP
2003-310627 May 2003 JP
2003-530921 October 2003 JP
2003-339730 December 2003 JP
2004-147701 May 2004 JP
2005027026 January 2005 JP
2005-066316 March 2005 JP
2005-074088 March 2005 JP
2005-534451 November 2005 JP
2006-6410 January 2006 JP
2006-116194 May 2006 JP
2006-158525 June 2006 JP
2006-218296 August 2006 JP
2006217716 August 2006 JP
2006-288431 October 2006 JP
2007-050181 March 2007 JP
2007-229454 September 2007 JP
2007-527747 October 2007 JP
2008-508065 March 2008 JP
2008-119250 May 2008 JP
2009-511206 March 2009 JP
2009-523567 June 2009 JP
2010-514923 May 2010 JP
5208761 June 2013 JP
WO 92/22259 December 1992 WO
WO 93/14708 August 1993 WO
WO 93/16646 September 1993 WO
WO 93/20877 October 1993 WO
WO 94/21183 September 1994 WO
WO 95/09572 April 1995 WO
WO 96/30885 October 1996 WO
WO 98/26739 June 1998 WO
WO 98/35621 August 1998 WO
WO 98/37815 September 1998 WO
WO 99/52489 October 1999 WO
WO 01/54590 August 2001 WO
WO 01/67970 September 2001 WO
WO 01/95810 December 2001 WO
WO 02/062241 August 2002 WO
WO 2004/012615 February 2004 WO
WO 2004/026104 April 2004 WO
WO 2004/032754 April 2004 WO
WO 2004/032762 April 2004 WO
WO 2004/032763 April 2004 WO
WO 2004/037095 May 2004 WO
WO 2004/098426 November 2004 WO
WO 2004/112618 December 2004 WO
WO 2005/122917 December 2005 WO
WO 2006/012797 February 2006 WO
WO 2006/042210 April 2006 WO
WO 2006/058223 June 2006 WO
WO 2006/063199 June 2006 WO
WO 2006/083988 August 2006 WO
WO 2006/119139 November 2006 WO
WO 2006/119376 November 2006 WO
WO 2006/129465 December 2006 WO
WO 2007/008703 January 2007 WO
WO 2007/008710 January 2007 WO
WO 2007/040818 April 2007 WO
WO 2007/047380 April 2007 WO
WO 2007/047531 April 2007 WO
WO 2007/056590 May 2007 WO
WO 2007/087272 August 2007 WO
WO 2007/143665 December 2007 WO
WO 2008/016886 February 2008 WO
WO 2008/042021 April 2008 WO
WO 2008/049084 April 2008 WO
WO 2008/130793 October 2008 WO
WO 2009/018406 February 2009 WO
WO 2009/027065 March 2009 WO
WO 2009/046234 April 2009 WO
WO 2009/120992 October 2009 WO
WO 2010/068783 June 2010 WO
WO 2011/008672 January 2011 WO
WO 2011/052939 May 2011 WO
WO 2011/144911 November 2011 WO
WO 2012/061722 May 2012 WO
WO 2012/135705 October 2012 WO
WO 2013/018934 February 2013 WO
WO 2013/062978 May 2013 WO
Other references
  • Partial International Search Report for PCT/US2008/071702, Feb. 25, 2009 (2 pages).
  • International Search Report for PCT/US2008/071702, May 19, 2009 (10 pages).
  • European Examination Report for Application No. 08796912.7, Jul. 12, 2010 (8 pages).
  • International Preliminary Report on Patentability for PCT/US2008/071702, Feb. 2, 2010 (12 pages).
  • European Search Report for Application No. 12177330.3, dated Jan. 8, 2013 (6 pages).
  • European Search Report for Application No. 12177326.1, dated Jun. 26, 2013 (6 pages).
  • European Examination Report for 12177330.3, dated May 28, 2014 (6 pages).
  • European Examination Report for 12177328.7, dated May 28, 2014 (5 pages).
  • Technology Overview, printed from www.harmonicscalpel.com, Internet site, website accessed on Jun. 13, 2007, (3 pages).
  • Sherrit et al., “Novel Horn Designs for Ultrasonic/Sonic Cleaning Welding, Soldering, Cutting and Drilling,” Proc. SPIE Smart Structures Conference, vol. 4701, Paper No. 34, San Diego, CA, pp. 353-360, Mar. 2002.
  • AST Products, Inc., “Principles of Video Contact Angle Analysis,” 20 pages, (2006).
  • Lim et al., “A Review of Mechanism Used in Laparoscopic Surgical Instruments,” Mechanism and Machine Theory, vol. 38, pp. 1133-1147, (2003).
  • Gooch et al., “Recommended Infection-Control Practices for Dentistry, 1993,” Published: May 28, 1993; [retrieved on Aug. 23, 2008]. Retrieved from the Internet: URL: http//wonder.cdc.gov/wonder/prevguid/p0000191/p0000191.asp (15 pages).
  • Huston et al., “Magnetic and Magnetostrictive Properties of Cube Textured Nickel for Magnetostrictive Transducer Applications,” IEEE Transactions on Magnetics, vol. 9(4), pp. 636-640 (Dec. 1973).
  • Incropera et al., “Fundamentals of Heat and Mass Transfer”, Wiley, New York (1990). (Book—not attached).
  • F. A. Duck, “Optical Properties of Tissue Including Ultraviolet and Infrared Radiation,” pp. 43-71 in Physical Properties of Tissue (1990).
  • Orr et al., “Overview of Bioheat Transfer,” pp. 367-384 in Optical-Thermal Response of Laser-Irradiated Tissue, A. J. Welch and M. J. C. van Gemert, eds., Plenum, New York (1995).
  • Campbell et al, “Thermal Imaging in Surgery,” p. 19-23, in Medical Infrared Imaging, N. A. Diakides and J. D. Bronzino, Eds. (2008).
  • Sullivan, “Cost-Constrained Selection of Strand Diameter and Number in a Litz-Wire Transformer Winding,” IEEE Transactions on Power Electronics, vol. 16, No. 2, Mar. 2001, pp. 281-288.
  • Sullivan, “Optimal Choice for Number of Strands in a Litz-Wire Transformer Winding,” IEEE Transactions on Power Electronics, vol. 14, No. 2, Mar. 1999, pp. 283-291.
  • Graff, K.F., “Elastic Wave Propagation in a Curved Sonic Transmission Line,” IEEE Transactions on Sonics and Ultrasonics, SU-17(1), 1-6 (1970).
  • Makarov, S. N., Ochmann, M., Desinger, K., “The longitudinal vibration response of a curved fiber used for laser ultrasound surgical therapy,” Journal of the Acoustical Society of America 102, 1191-1199 (1997).
  • Morley, L. S. D., “Elastic Waves in a Naturally Curved Rod,” Quarterly Journal of Mechanics and Applied Mathematics, 14: 155-172 (1961).
  • Walsh, S. J., White, R. G., “Vibrational Power Transmission in Curved Beams,” Journal of Sound and Vibration, 233(3), 455-488 (2000).
  • http://www.apicalinstr.com/generators.htm.
  • http://www.dotmed.com/listing/electrosurical-unit/ethicon/ultracision-g110-/1466724.
  • http:/www.ethicon.com/gb-en/healthcare-professionals/products/energy-devices/capital//ge . . . .
  • http://www.4-traders.com/JOHNSON-JOHNSON-4832/news/Johnson-Johnson-Ethicon-E . . . .
  • http://www.medicalexpo.com/medical-manufacture/electrosurgical-generator-6951.html.
  • http://www.megadyne.com/esgenerator.php.
  • http://www.valleylab.com/product/es/generators/index.html.
  • Covidien 501(k) Summary Sonicision, dated Feb. 24, 2011 (7 pages).
  • “U.S. Appl. No. 13/751,680, filed Jan. 28, 2013.”
  • “U.S. Appl. No. 14/136,836, filed Dec. 20, 2013.”
  • U.S. Appl. No. 13/804,205, filed Mar. 14, 2013.
  • U.S. Appl. No. 13/843,295, filed Mar. 15, 2013.
  • U.S. Appl. No. 13/833,706, filed Mar. 15, 2013.
  • “U.S. Appl. No. 14/057,682, filed Oct. 18, 2013.”
Patent History
Patent number: 9439669
Type: Grant
Filed: Mar 28, 2013
Date of Patent: Sep 13, 2016
Patent Publication Number: 20130226208
Assignee: Ethicon Endo-Surgery, LLC (Guaynabo, PR)
Inventors: Eitan T. Wiener (Cincinnati, OH), Foster B. Stulen (Mason, OH), Michael J. Stokes (Cincinnati, OH), Karen K. Isaacs (Burlington, KY), William J. Kraimer (Mason, OH)
Primary Examiner: Ashley Fishback
Application Number: 13/852,539
Classifications
Current U.S. Class: Structure Of Transducer Or Probe Assembly (600/459)
International Classification: A61B 17/32 (20060101); A61B 17/30 (20060101); A61B 17/3205 (20060101); A61B 17/22 (20060101); A61B 17/00 (20060101); A61B 17/29 (20060101);