Patents Issued in August 12, 2003
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Patent number: 6605633Abstract: The present invention relates to novel compounds which inhibit the action of CXC chemokines, such as IL-8, Gro, NAP-2, ENA-78 etc., on their receptors, to the process for their preparation and to their use for obtaining drugs. According to the invention, said compounds are novel indole derivatives selected from the group consisting of: i) the products of the formula in which: X is a double bond —C═C— or a sulfur atom; R1 is a halogen, a nitro group, a trifluoromethyl group or a C1-C3 alkyl group; R2, R3 and R4 are each independently a hydrogen atom, a halogen, a C1-C3 alkyl group, a nitro group, a trifluoromethyl group or a cyano group, or R2 and R3 form a fused aromatic ring together with the aromatic ring to which they are attached; and n is equal to 2 or 3; and ii) esters of the compounds of formula I and addition salts of said compounds with a mineral or organic base.Type: GrantFiled: May 16, 2002Date of Patent: August 12, 2003Assignee: Fournier Industrie et SanteInventors: Jean-Luc Paquet, Martine Barth, Didier Pruneau, Pierre Dodey
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Patent number: 6605634Abstract: The present invention comprises a new class of novel aryl and heteroaryl substituted fused pyrrole compounds useful for the prophylaxis and treatment of diseases or conditions, such as TNF-&agr;, IL-1&bgr;, IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. In particular, the compounds of the invention are useful for the prophylaxis and treatment of diseases or conditions involving inflammation. Accordingly, the invention also comprises pharmaceutical compositions comprising the compounds of the invention, methods for the prophylaxis and treatment of inflammation and other maladies, such as pain and diabetes, using the compounds and compositions of the invention, and intermediates and processes useful for the preparation of compounds of the invention. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.Type: GrantFiled: June 18, 2002Date of Patent: August 12, 2003Assignee: Amgen, Inc.Inventors: Jeffery A. Zablocki, Eugene Tarlton, Jr., James P. Rizzi, Nathan B. Mantlo
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Patent number: 6605635Abstract: N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)benzyl aromatic sulfonamides and N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)phenyl aromatic sulfonamides compounds in accordance with the animal test, are active in the prevention and the treatment of cardiac arrhythmia. These compounds are prepared as corresponding diamines by the condensation of optionally substituted aromatic sulfochlorides with p-hydroxybenzylamine, p-aminophenol, or the like, which followed by the Mannich reaction of the resulted corresponding aromatic sulfamides with formaldehyde and secondary amines; or directly obtained by the reaction of the aromatic sulfamides with 4-amino-2,6-bis-disubstituted aminomethylphenol. Subsequently, the diamines are reacted with various acids to provide their salts.Type: GrantFiled: June 7, 2002Date of Patent: August 12, 2003Assignee: Shanghai Institute of Materia Medica Chinese Academy of ScienceInventors: Donglu Bai, Weizhou Chen, Yunxin Bu, Yiping Wang, Yueli Dong, Aili Kang
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Patent number: 6605636Abstract: The present invention provides a novel form of atorvastatin hemi-calcium designated Form VII and novel processes for its preparation whereby another crystalline form of atorvastatin hemi-calcium is suspended in ethanol, preferably absolute ethanol, and is converted to the new form, which is then isolated. The present invention further provides a method of reducing the plasma low density lipoprotein level in patients suffering from or susceptible to hypercholesterolemia and compositions and dosage forms for practicing the invention.Type: GrantFiled: November 5, 2001Date of Patent: August 12, 2003Assignee: Teva Pharmaceutical Industries Ltd.Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz
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Patent number: 6605637Abstract: The invention concerns novel lipoic acid derivatives, which have an inhibiting action with respect to NO-synthase enzymes producing nitrogen monoxide NO and/or are agents enabling the regeneration of antioxidants or entities trapping reactive oxygen species (ROS) and intervening in a more general manner in the redox status of thiol groups. The invention also concerns methods for preparing them, pharmaceutical compositions containing them and their use for therapeutic purposes, particularly their use as NO-synthase inhibitors and/or as agents acting more generally in the redox status of thiol groups.Type: GrantFiled: September 27, 2001Date of Patent: August 12, 2003Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)Inventors: Jeremiah Harnett, Michel Auguet, Pierre-Etienne Chabrier de Lassauniere
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Patent number: 6605638Abstract: The invention relates to the use of branched chain fatty acids (BFAs) and their derivatives for inhibition of the activity of P-glycoprotein (P-gp). In particular, the invention relates to the use of BFAs and their derivatives in the treatment of multi-drug resistant (MDR) tumors associated with increased activity of P-glycoprotein. The invention also relates to the use of the above-mentioned molecules for administration of biologically active molecules and diagnostic agents into cells associated with increased activity of P-gp, and for increasing accumulation of biologically active molecules and diagnostic agents in organs protected by biological barriers.Type: GrantFiled: December 20, 2000Date of Patent: August 12, 2003Assignee: D-Pharm LimitedInventors: Alexander Kozak, Roman Kamburg
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Patent number: 6605639Abstract: It has been newly found out that ascochlorin, which is a publicly known fat-soluble antibiotic, and its homologues serve as a ligand of retinoid X receptor and react in vivo with the amino group of serum protein to form Schiff bases without showing any side effect of retinoid. Ascochlorin and its homologues are usable in treating and/or preventing a disease or condition which can be relieved by the retinoid X receptor ligand-dependent gene transcriptional regulation (for example, diseases caused by the expression of insulin resistance, hypertension, cerebrovascular diseases, rheumatoid arthritis, autoimmune disease, Ca metabolic disorder, complication of diabetes, arteriosclerosis, etc.). Moreover, they can inhibit denaturation and/or necrosis of pancreatic Langerhans islet &bgr;-cells and, therefore, are usable in making these cells to sustain the insulin productivity.Type: GrantFiled: June 14, 2001Date of Patent: August 12, 2003Assignee: Nuclear Receptor Research, Ltd.Inventors: Gakuzo Tamura, Kunio Ando, Junji Magae, Takafumi Uchida
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Patent number: 6605640Abstract: The present invention is directed to methods for treating diminished visual acuity in a human patient who has been diagnosed as suffering from a disease or disorder of the posterior region of the eye. These involve topical application to the eye, an amount of acetylcholine esterase inhibitor containing composition is carried out so that it is sufficient to provide a therapeutic benefit to alleviate the diminished visual acuity in the human patient. The composition is administered at bedtime after an eye straining work for about 20 minutes.Type: GrantFiled: January 31, 2001Date of Patent: August 12, 2003Inventor: Gerard M. Nolan
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Patent number: 6605641Abstract: 20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z), 8(Z), 11(Z), 14(Z)-tetraenoic acid, 20-hydroxyeicosa-5(Z), 14(Z)-dienoic acid and 20-, 21-dimethyl 20-HETE. Preferable 20-HETE antagonists include 5(S)-HETE, 15(S)-HETE, 19(S)-HETE, 19-hydroxynonadeca-5(Z), 8(Z), 11(Z), 14(Z)-tetraenoic acid and 20-hydroxyeicosa 6(Z), 15(Z)-dienoic acid.Type: GrantFiled: December 14, 2001Date of Patent: August 12, 2003Assignee: MCW Research FoundationInventors: Richard J. Roman, John R. Falck, Magdalena Alonso-Galicia, Elizabeth R. Jacobs, David R. Harder
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Patent number: 6605642Abstract: The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood and in the intracellular environment such as occurs with diabetes. The structural and functional integrity of the affected molecules become perturbed by these modifications and can result in severe consequences. The compounds of the present invention can be used to inhibit this process of nonenzymatic glycation and therefore to inhibit some of the ill effects caused by diabetes or by aging. The compounds are also useful for preventing premature aging, spoilage of proteins in food and can prevent discoloration of teeth.Type: GrantFiled: March 8, 2001Date of Patent: August 12, 2003Assignee: City of HopeInventors: Samuel Rahbar, Iraj Lalezari
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Patent number: 6605643Abstract: The invention relates to storage stable insect repellent emulsion formulations containing N,N-Diethyl-m-toluamide, together with water, a film-forming polymer and an emulsifier-emulsion stabilizer.Type: GrantFiled: November 24, 1997Date of Patent: August 12, 2003Assignee: Schering-Plough HealthCare Products, Inc.Inventor: Jamie S. Ross
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Patent number: 6605644Abstract: A regimen for the administration of tramadol for the treatment of analgesia is described. The regimen involves a slower initial titration rate of tramadol which results in a significantly lower percentage of discontinuations of therapy due to a lower incidence and severity of side effects.Type: GrantFiled: October 26, 2001Date of Patent: August 12, 2003Assignee: Ortho-McNeil Pharmaceutical, Inc.Inventors: Marc Kamin, William Olson
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Patent number: 6605645Abstract: Nobel polyamine compounds and polyamine compounds having carcinostatic action are provided. There are also provided anticancer agents containing as active ingredient at least one of polyamine compounds represented by the following Formula (I) or (III) and/or pharmaceutically acceptable salts thereof. Specifically, there are provided anticancer agents containing as active ingredient at least one of 1,18-bis(ethylamino)-5,14-diazaoctadecane, 1,16-bis(cyclopropylmethylamino)-5,12-diazahexadecane, 1,17-bis(cyclopropylmethylamino)-5,13-diazaheptadecane and/or pharmaceutically acceptable salts thereof.Type: GrantFiled: October 16, 2001Date of Patent: August 12, 2003Assignee: RikenInventor: Masaaki Iwata
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Patent number: 6605646Abstract: A vitamin B12 supplement composition comprising vitamin B12 with and/or without added folic acid that is essentially free of antioxidants, such as vitamin C, as well as iron is disclosed. Also disclosed are methods of using this vitamin composition to prevent brain and nervous system damage, such as peripheral nerve damage, as well as pernicious anemia, such as where such anemia is caused by a deficiency of vitamin B12 deficiency.Type: GrantFiled: August 9, 2002Date of Patent: August 12, 2003Assignee: Upsher-Smith Laboratories, Inc.Inventor: Victor D. Herbert
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Patent number: 6605647Abstract: A method of producing synthetic fuels by hydrogenating carbon monoxide comprising contacting a feed gas containing carbon monoxide and hydrogen with a metal sulfide catalyst comprising: (1) at least one element selected from the group consisting of Rh, Pd, Pt, and Hf; and optionally (2) solid acid.Type: GrantFiled: December 28, 2000Date of Patent: August 12, 2003Assignee: President of Tohoku UniversityInventors: Muneyoshi Yamada, Naoto Koizumi, Yosuke Takahashi
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Patent number: 6605648Abstract: A method of producing an open, porous structure having an outer surface defining a shape having a bulk volume and having interconnecting openings extending throughout said volume and opening through said surface, and products resulting from the method. The method comprises preparing a viscous mixture comprising a sinterable powder dispersed in a sol of a polymer in a primary solvent, replacing the primary solvent with a secondary liquid in which the polymer is insoluble to produce a gel comprising an open polymeric network having the sinterable powder arranged therein, removing the secondary liquid from the gel; removing the polymer network, and sintering the sinterable powder to form the open, porous structure. Also disclosed are shaped, porous products resulting from methods of the invention.Type: GrantFiled: April 6, 1999Date of Patent: August 12, 2003Assignee: Phillips Plastics CorporationInventors: James R. Johnson, Michael Edward Frencl
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Patent number: 6605649Abstract: Polyvinyl chloride resin compositions and methods of preparation and use thereof for increasing the degree of whiteness in finished polyvinyl chloride foam. The resin compositions contain sulfur compounds selected from sulfonic acid derivatives, sulfinic acid derivatives, and mercapto acetic acid sodium salt, and optionally contain water soluble salts and/or t-butyl hydroperoxide.Type: GrantFiled: January 21, 2003Date of Patent: August 12, 2003Assignee: Occidental Chemical CorporationInventors: Michael T. Moran, Thomas E. Moses, Sherry Rohn Clancy
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Patent number: 6605650Abstract: In a process generating a polyurethane foam by forming a mixture including isocyanate and polyol reactants, catalyst, and blowing agent, which mixture reacts exothermically to yield a rigid polyurethane foam, there is included expandable polystyrene beads made of a polystyrene that has a softening point at or below the maximum temperature reached during the exothermic reaction.Type: GrantFiled: March 11, 2002Date of Patent: August 12, 2003Assignee: Hunter Paine Enterprises, LLCInventor: Arthur J. Roth
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Patent number: 6605651Abstract: This invention provides a method and material compositions for producing objects containing in whole, or in part, biomedical polymers, especially those having dental use. Microwave sensitive material compositions are injected under pressure into a mold, the mold containing a replica of a body tissue or tissues. While hydraulic pressure is maintained on the material, a microwave source emits metered electromagnetic energy for hardening the material in the 3-dimensionally defined space. For dental and other applications, the mold making, injection and hardening are done sequentially to rapidly produce an object which accurately fits the mold.Type: GrantFiled: September 8, 1999Date of Patent: August 12, 2003Assignee: Biomat Sciences, Inc.Inventors: Ivan Stangel, Jingwei Xu
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Patent number: 6605652Abstract: An energy curable printing ink composition containing a branched polyester comprising monofunctional and difunctional components having an excess functionality of about 0.1 to 0.20. Also described is a method of reducing misting and/or dot gain in an energy curable printing ink composition by adding such branched polyesters to the composition.Type: GrantFiled: January 11, 2000Date of Patent: August 12, 2003Assignee: Sun Chemical CorporationInventors: Edward Stone, Gordon Kotora, Neil Young
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Patent number: 6605653Abstract: An ink jet printing method, comprising the steps of: A) providing an ink jet printer that is responsive to digital data signals; B) loading said printer with ink-receptive elements comprising a support having thereon a porous ink-receptive layer; C) loading said printer with an ink jet ink composition comprising water, a humectant, and a water-dispersible polymeric latex having contained therein a delocalized cationic azo dye derived from the quaternization of a nitrogen heterocyclic azo dye having the following formula: and D) printing on an ink-receptive substrate using said ink jet ink in response to said digital data signals.Type: GrantFiled: August 22, 2000Date of Patent: August 12, 2003Assignee: Eastman Kodak CompanyInventors: Huijuan Chen, Leslie Shuttleworth
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Patent number: 6605654Abstract: A new composition, method, and apparatus for sealing and inflating a flat tire are described. The new composition includes a gas-generating agent and an activator, along with a sealant. In use, a gas propellant is generated in situ when the gas-generating agent is mixed with the activator. For example, carbon dioxide is generated when carbonates, such as baking soda, and an acid are mixed. The carbon dioxide gas generated in this manner can inflate a flat tire to a desired pressure. In addition to carbon dioxide, nitrogen gas, noble gases, and nitrous oxide gas may also be used instead.Type: GrantFiled: July 14, 2000Date of Patent: August 12, 2003Assignee: Pennzoil-Quaker State CompanyInventors: Jiafu Fang, Dewey P. Szemenyei, Troy H. Scriven
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Patent number: 6605655Abstract: Provided is a polyamide resin composition comprising a melt blend of (A) a polyamide resin, (B) a phyllosilicate, and (C) an olefin compound having a carboxylic acid anhydride group in the molecule or a polymer of the olefin compound, in which the phyllosilicate (B) has a reactive functional group bonded thereto and is such that the exchangeable metal ions existing in the inter layers are ion-exchanged with organic onium ions. The composition has a reduced inorganic ash content and has both high stiffness and high ductility. Optionally, the composition contains an inorganic filler apart from the phyllosilicate, an impact modifier, and a flame retardant, still having high stiffness and high ductility.Type: GrantFiled: March 29, 2000Date of Patent: August 12, 2003Assignee: Toray Industries, Inc.Inventors: Koya Kato, Toru Nishimura, Toru Yamanaka
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Patent number: 6605656Abstract: A thermoplastic olefin resin composition having improved resistance to surface impacts, such as scratching, marring and gouging, is provided. The thermoplastic olefin resin comprises a blend of polyolefin alloy and polyamide components. The components have relative melt flow rates such that the polyamide component is selectively segregated toward the front of a melt flow. A compatibilizing agent is added to overcome the natural incompatibility of the polyolefin alloy and polyamide components of the resin. The thermoplastic olefin resin may further include a filler material when increased stiffness or modulus is desired.Type: GrantFiled: November 29, 2000Date of Patent: August 12, 2003Assignee: Visteon Global Technologies, Inc.Inventors: Rose A. Ryntz, Beth M. Wichterman
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Patent number: 6605657Abstract: There is provided a method of preparing a thermoplastic starch and synthetic polymer blend, said method comprising the steps of: (a) providing a starch suspension comprising starch, water and a plasticizer, preferably glycerol; (b) obtaining a thermoplastic starch from the starch suspension by causing gelatinization and plasticization of said starch suspension by exerting heat and pressure on said starch suspension in a first extrusion unit; (c) evaporating and venting off residual water from said thermoplastic starch to obtain a substantially moisture-free thermoplastic starch; (d) obtaining a melt of a synthetic polymer or polymer blend in a second extrusion unit; and (e) combining the melt obtained from step (d) with the substantially moisture-free thermoplastic starch. Also provided are compositions of matter comprising immiscible blends of thermoplastic starches, polymers, and compatibilizers.Type: GrantFiled: December 27, 1999Date of Patent: August 12, 2003Assignee: Polyvalor Societe en CommanditeInventors: Basil D. Favis, Francisco Rodriguez, Bruce A. Ramsay
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Patent number: 6605658Abstract: Stabilizing mixtures for organic polymers comprising: a) at least one compound belonging to the group of pyrazolones; b) at least one compound belonging to the group of organic phosphites or phosphonites; c) at least one compound belonging to the group of sterically hindered phenols; and d) at least one compound belonging to the group of sterically hindered amines. The above mixtures are useful in the stabilization to degradation caused by oxygen, heat and/or light, of organic polymers.Type: GrantFiled: November 22, 2000Date of Patent: August 12, 2003Assignee: Great Lakes Chemical (Europe) GmbHInventors: Fabio Broussard, Daniele Girelli, Maria Lucia Wis, Carlo Neri, Vincenzo Malatesta
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Patent number: 6605659Abstract: A thermoplastic resin composition contains an aromatic carbonate resin, a rubber modified graft copolymer comprising a discontinuous rubber phase dispersed in a continuous rigid thermoplastic phase, wherein at least a portion of the rigid thermoplastic phase is chemically grafted to the rubber phase, and a flame retarding amount of an alkali metal or alkaline earth metal salt of an alkylbenzenesulfonic acid flame retardant.Type: GrantFiled: December 20, 2000Date of Patent: August 12, 2003Assignee: General Electric CompanyInventors: Kirk J. Blackburn, Robert R. Gallucci, Emil M. Georgiev
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Patent number: 6605660Abstract: A polyarylene sulfide resin composition has an excellent moldability to produce moldings excellent in mechanical properties without corroding or staining metal parts such as molds during molding, and comprises 100 parts by weight of a polyarylene sulfide resin (A) and 0.05 to 3 parts by weight of zinc oxide whiskers (B).Type: GrantFiled: October 25, 2001Date of Patent: August 12, 2003Assignee: Polyplastics Co., Ltd.Inventors: Masaaki Nakamura, Hiroyuki Amano
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Patent number: 6605661Abstract: A structural element having a plurality of recycled, convoluted scrap metal turnings or shavings disposed randomly within a transparent plastic moldment. The turnings or shavings are interlocked with each other and with the plastic and substantially fill the moldment. A method of forming the structural element is disclosed.Type: GrantFiled: December 13, 2000Date of Patent: August 12, 2003Inventor: Demir Hamami
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Patent number: 6605662Abstract: A process for preparing aqueous polymer dispersions comprises first of all subjecting ethylenically unsaturated monomers to free-radical aqueous emulsion polymerization to prepare an aqueous dispersion of a polymer 1 having a glass transition temperature Tg1, then dissolving further, comparatively hard monomers in the dispersed particles of the polymer 1, and subsequently carrying out free-radical polymerization of said monomers dissolved in said particles.Type: GrantFiled: May 15, 2001Date of Patent: August 12, 2003Assignee: BASF AktiengesellschaftInventors: Cheng-Le Zhao, Joachim Roser, Eckehardt Wistuba, Bernhard Schuler, Klemens Mathauer
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Patent number: 6605663Abstract: A process is for preparing polyvinyl alcohol-stabilized addition polymers based on (meth)acrylate monomers in the form of their aqueous dispersions and water-redispersible dispersion powders by means of free-radically initiated emulsion polymerization or suspension polymerization of one or more monomers selected from the group consisting of the esters of acrylic acid and methacrylic acid and, if desired, further monomers copolymerizable therewith in the presence of one or more protective colloids from the group of the polyvinyl alcohols and, if appropriate, with drying of the resultant aqueous dispersion, which includes a) conducting polymerization in the presence of from 0.001% to 0.02% by weight of initiator and, if desired, from. 0.001% to 0.Type: GrantFiled: May 31, 2000Date of Patent: August 12, 2003Assignee: Wacker Polymer Systems GmbH & Co. KGInventor: Hans-Peter Weitzel
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Patent number: 6605664Abstract: A pigment dispersion is composed of a pigment, a polymer and a solvent. The polymer has, on side chains thereof, carboxyl groups derived from a dibasic acid. The pigment dispersion is useful for writing instruments and printers.Type: GrantFiled: February 11, 2000Date of Patent: August 12, 2003Assignee: Dainichiseika Color & Chemicals Mfg. Co., Ltd.Inventors: Kazuo Kanou, Yoshifumi Sugito, Hiroaki Saikatsu
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Patent number: 6605665Abstract: A process for the preparation of fiber-reinforced moldings for motor vehicles wherein the molding comprises a) from 1 to 96.86% by weight of at least one polycondensate, b) from 1 to 12% by weight of at least one particulate graft copolymer whose soft phase has a glass transition temperature below 0° C. and whose median particle size is from 50 to 1000 nm, c) from 1 to 12% by weight of at least one copolymer made from the following monomers, c1) from 50 to 90% by weight of at least one vinylaromatic monomer, and c2) from 10 to 50% by weight of acrylonitrile and/or methacrylonitrile, based in each case on component c, d) from 0 to 20% by weight of e) from 0.01 to 15% by weight of a polycarbonate, f) from 0.01 to 2% by weight of a carbon black, g) from 0 to 12% by weight of a polymer other than component B, h) from 0 to 20% by weight of a polyester other than component A, i) from 0.Type: GrantFiled: July 17, 2001Date of Patent: August 12, 2003Assignee: BASF AktiengesellschaftInventors: Michael Fischer, Manfred Knoll, Christophe Ginss, Stephan Berz
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Patent number: 6605666Abstract: A polyurethane dispersion and method of making are provided. The dispersion is stable in an alcohol-water mixture. The dispersion is a reaction product of: (i) at least one oligomeric polyactive hydrogen compound, wherein said compound is an alkyl, aryl, or aralkyl structure optionally substituted in and/or on the chain by N, O, S and combinations thereof, and wherein the compound is insoluble in 50:50 weight percent of said alcohol-water mixture; (ii) at least one polyisocyanate, and (iii) at least one polyactive hydrogen compound soluble in the alcohol-water mixture selected from the group consisting of a compound containing an ionic group, a compound containing a moiety capable of forming an ionic group, a compound containing a polyester, polyether, or polycarbonate group having a ratio of 5 or less carbon atoms for each oxygen atom, and mixtures thereof; and (b) at least one polyfunctional chain extender.Type: GrantFiled: July 27, 2000Date of Patent: August 12, 2003Assignee: 3M Innovative Properties CompanyInventors: Matthew T. Scholz, Steven S. Kantner, Kristen L. Comstock, Christopher J. Brown
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Patent number: 6605667Abstract: An adhesive composition includes a polymerizable adhesive monomer and at least one antioxidant stabilizer, and/or a container for storing said monomer composition that includes an antioxidant stabilizer. The antioxidant stabilizer provides superior stabilization and shelf-life of the composition and/or the container, and may enhance wound healing properties of the monomer composition.Type: GrantFiled: September 8, 2000Date of Patent: August 12, 2003Assignee: Closure Medical CorporationInventors: Ibraheem T. Badejo, Jaime Ayarza, Anthony Voiers, Roy F. Thompson, Jr., Gabriel N. Szabo, Robert V. Toni, William S. C. Nicholson
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Patent number: 6605668Abstract: The invention pertains to water-dissipatable polymers comprising lipophilic polymers having pendant sulfonic acid salt groups and, optionally, pendant nonionic groups, methods of making such water-dissipatable polymers and the use of such polymers in aqueous systems, including aqueous coating compositions. The invention also pertains to addition polymer polyols having such pendant sulfonic acid salt groups and, optionally, pendant nonionic groups, their methods of manufacture and their use in aqueous systems, including aqueous coating compositions. The polymers of the invention may be used as, for example, binders, emulsifying agents and dispersing agents in aqueous systems, especially aqueous coating compositions.Type: GrantFiled: May 10, 2000Date of Patent: August 12, 2003Assignee: Akzo Nobel N.V.Inventors: Roelof Buter, Andreas Henricus Johannes Roelofs
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Patent number: 6605669Abstract: Coating compounds curable by means of high-energy radiation, comprising as binder A) at least one (meth)acrylic copolymer containing olefinic double bonds capable of free-radical polymerization and hydroxyl groups with a C═C equivalent weight from 100 to 10,000 and an OH-value from 20 to 250 mg KOH/g, which is prepared from monomers comprising: A1) at least one olefinically unsaturated, epoxy-functional monomer capable of free-radical polymerization, A2) at least one olefinically unsaturated, carboxy-functional monomer capable of free-radical polymerization and A3) at least one further olefinically unsaturated monomer capable of free-radical polymerization which is different from A1) and A2), and B) at least one component with free isocyanate groups and process for multilayer coating using the coating compounds.Type: GrantFiled: April 3, 2001Date of Patent: August 12, 2003Assignee: E. I. du Pont de Nemours and CompanyInventors: Morenike Awokola, Carmen Flosbach, Helmut Loeffler, Volker Paschmann
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Patent number: 6605670Abstract: Methods of making low molecular weight methylene acceptors are provided. The methylene acceptors are prepared by reacting a polyhydric phenol with an aromatic olefinic compound in the presence of an acid catalyst, and then further reacting the products of the first reaction with an N-methylol lactam derivative. Derivatives made by the above method, as well as rubber compositions using these derivatives are also provided.Type: GrantFiled: November 6, 2001Date of Patent: August 12, 2003Assignee: Indspec Chemical CorporationInventors: Raj B. Durairaj, Mark A. Lawrence
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Patent number: 6605671Abstract: The invention discloses an improved process for the production of cross-linked rubber particles. The cross-linking agents are added to the aqueous rubber dispersions and converted at relatively high temperatures without inertization of the reaction mix and without pressurizing of an inert gas. The cross-linked rubber particles are suitable, for example, for the production of technical rubber products and for various tire components.Type: GrantFiled: July 17, 2001Date of Patent: August 12, 2003Assignee: Bayer AktiengesellschaftInventor: Werner Obrecht
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Patent number: 6605672Abstract: There is provided an excellent impact modifier for a vinyl chloride resin. There is used, as an excellent impact modifier, a copolymer which is prepared by polymerizing 10 to 70% by weight of a monomer or monomers containing 60 to 100% by weight of at least one vinyl monomer selected from the group consisting of a (meth)acrylate compound, an aromatic vinyl compound, a vinyl cyanide compound and vinyl chloride, and 0 to 40% by weight of the other monomer copolymerizable therewith, in the presence of 30 to 90% by weight of a hollow rubber particle of which glass transition temperature Tg is at most 0° C. and a void ratio is 3 to 90% by volume in a latex state, and which contains a cross linking agent in an amount of 0.1 to 5 parts by weight based on 100 parts by weight of the total rubber component monomer.Type: GrantFiled: June 6, 2001Date of Patent: August 12, 2003Assignee: Kaneka CorporationInventors: Akira Takaki, Toshio Mizuta, Tomomichi Hashimoto, Toshiyuki Mori
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Patent number: 6605673Abstract: The invention relates to crosslinked polymerizates which are capable of absorbing, which are based on partially neutralized, monoethylenically unsaturated monomers that carry acidic groups, which exhibit improved properties, in particular, with regard to their ability to transport liquids when in a swollen state, and which are subsequently crosslinked on the surface thereof at temperatures ≧150° C. with a combination consisting of polyol used as a subsequent crosslinker compound and of a cation provided in the form of an aqueous solution.Type: GrantFiled: August 29, 2001Date of Patent: August 12, 2003Assignee: Stockhausen GmbH & Co., KGInventors: Richard Mertens, Jörg Harren
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Patent number: 6605674Abstract: This invention is directed to structurally-modified water-soluble polymers prepared by initiating polymerization of an aqueous solution of monomers under free radical polymerization conditions to form a polymer solution and adding at least one structural modifier to the polymer solution after at least 30% polymerization of the monomers has occurred, and to use of the water-soluble cross-linked polymers as flocculating agents.Type: GrantFiled: June 29, 2000Date of Patent: August 12, 2003Assignee: Ondeo Nalco CompanyInventors: Wesley L. Whipple, Chidambaram Maltesh, Cathy C. Johnson, Ananthasubramanian Sivakumar, Tracey M. Guddendorf, Angela P. Zagala
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Patent number: 6605675Abstract: The invention provides for polymerization catalyst compositions, and for methods for introducing the catalyst compositions into a polymerization reactor. More particularly, the method combines a catalyst component containing slurry and a catalyst component containing solution to form the completed catalyst composition for introduction into the polymerization reactor. The invention is also directed to methods of preparing the catalyst component slurry, the catalyst component solution and the catalyst compositions, to methods of controlling the properties of polymer products utilizing the catalyst compositions, and to polymers produced therefrom.Type: GrantFiled: December 4, 2000Date of Patent: August 12, 2003Assignee: Univation Technologies, LLCInventors: Simon Mawson, Sun-Chueh Kao, Tae Hoon Kwalk, Timothy Roger Lynn, David H. McConville, Matthew Gary McKee, John Francis Szul, Kersten Anne Terry, Timothy T. Wenzel, Mark Gregory Goode, John Henry Oskam, Robert J. Jorgensen, Robert Harold Vogel
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Patent number: 6605676Abstract: The process is characterized by the use of catalyst systems consisting of a single metallocene catalyst activated with mixtures of at least 2 co-catalysts. The co-catalysts are aluminium alkyls, aluminoxanes or boron compounds. Different active centers are produced in the catalyst through the use of these mixed co-catalyst systems, each having different rates of initiation and completion of the polymerization reaction, which give rise to polyolefins with different molecular weights, resulting in products with broad bimodal or multimodal molecular weight distributions and the incorporation of co-monomer can be controlled by appropriate selection of the metallocene and use of combinations of different types of co-catalysts, as well as by varying the reactor pressure, the reaction temperature and the molar ratios between the various components of the catalyst system.Type: GrantFiled: December 28, 1995Date of Patent: August 12, 2003Assignee: Repsol Quimica, S.A.Inventors: Wilfried Michiels Vega, Antonio Munoz-Escalona
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Patent number: 6605677Abstract: Improved Group 8-10 transition metal based supported catalyst processes for the polymerization of olefins are described. Some of the improvements pertain to protocols for catalyst preparation and activation which improve the catalyst productivity in the presence of hydrogen as a molecular weight control agent.Type: GrantFiled: November 2, 2001Date of Patent: August 12, 2003Assignee: Eastman Chemical CompanyInventors: Gino Georges Lavoie, Peter Borden Mackenzie, Christopher Moore Killian, Thomas William Smith
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Patent number: 6605678Abstract: A polymer comprising recurring units of formula (1-1) or (1-2) wherein R1, R2, R3 and R4 are H or C1-15 alkyl, R1 and R2, and R3 and R4, taken together, may form a ring; R5 and R6 are H, C1-15 alkyl, acyl or alkylsulfonyl groups or C2-15 alkoxycarbonyl or alkoxyalkyl groups which may have halogen substituents; and k=0 or 1, and having a Mw of 1,000-500,000 is novel. A resist composition comprising the polymer as a base resin is sensitive to high-energy radiation, has excellent sensitivity, resolution, etching resistance, and minimized swell and lends itself to micropatterning with electron beams or deep-UV.Type: GrantFiled: December 3, 2002Date of Patent: August 12, 2003Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Tsunehiro Nishi, Mutsuo Nakashima, Tomohiro Kobayashi
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Patent number: 6605679Abstract: Olefins containing selected functional groups such as silyl, ether and alkenyl, and often containing a blocking group, may be copolymerized with unsubstituted olefins such as ethylene and propylene in the presence of certain coordination compounds of nickel or palladium. The resulting polymers are useful as molding resins, elastomers, in adhesives and for films.Type: GrantFiled: February 1, 2000Date of Patent: August 12, 2003Assignee: E. I. du Pont de Nemours and CompanyInventors: Lin Wang, Samuel David Arthur, Elizabeth Forrester McCord, Yueli Wang, Peter Arnold Morken, Lynda Kaye Johnson
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Patent number: 6605680Abstract: Low color, aromatic modified C5 hydrocarbon resins are disclosed. The resins are predominantly an aromatic modified piperylene resin. The resins are useful as tackifiers in hot melt adhesives and hot melt pressure sensitive adhesives.Type: GrantFiled: April 7, 2000Date of Patent: August 12, 2003Assignee: Eastman Chemical Resins, Inc.Inventors: Chretien P. L. C. Donker, Ester E. C.G. Gielens, Gerard A. Verrijzer
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Patent number: 6605681Abstract: A process is disclosed for a continuous, high temperature polymerization process for preparing a free radically polymerized epoxy-functional polymeric product. The process comprises continuously charging into a reactor at least one epoxy-functional acrylic monomer, and optionally at least one non-functional free radical polymerizable monomer. An optional free radical polymerization initiator may also be added. The reactor is maintained at an effective temperature for an effective period of time to cause polymerization of the monomers into a polymeric product, such that the polymeric product is formed substantially free of gel particles. A clear coating is also disclosed incorporating polymers of the present invention, such that the clear coating has a low Delta b value at standard conditions.Type: GrantFiled: July 12, 2000Date of Patent: August 12, 2003Assignee: Johnson Polymer, Inc.Inventors: Marco A. Villalobos, Warunee Srisiri-Sisson, Alan J. Pekarik, J. David Campbell
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Patent number: 6605682Abstract: The invention provides a resin molded article for optical products comprising a copolymer predominantly composed of methyl methacrylate and a styrenic monomer, wherein the number of foreign bodies contained in the resin molded article having a length of 210 mm, a width of 210 mm and a thickness of 3 mm as visually examined using a strain meter is about 150 or less, which is useful for a light transmitting plate employed in a liquid crystal display device because the possibility that the display screen looks whitely turbid due to the warp of the light transmitting plate, is reduced.Type: GrantFiled: March 28, 2001Date of Patent: August 12, 2003Assignee: Sumitomo Chemical Company, LimitedInventors: Ikuo Morisada, Kenji Manabe