Abstract: The invention relates to a structured mixed phase formed by the incorporation of a biological macromolecule into a liquid-crystal phase of amphiphiles, preferably a lamellar phase, wherein said biological macromolecule is present in said structured mixed phase in an amount of at least 5% by weight, based on the amphiphilic compounds constituting said liquid-crystal phase of amphiphiles, and wherein at least one of the two entities consisting of the biological macromolecules, on the one hand, and all the amphiphilic compounds, on the other, is of an uncharged nature. The biological macromolecules incorporated into the structured mixed phases of the invention are preferably selected from polynucleotides, particularly DNA or RNA, proteins and polysaccharides. The invention further relates to vesicles obtained by dispersion of the above structured mixed phases.

Abstract: The present invention provides a non-covalent coupling method for the preparation of sterically stabilized lipsomes which may be used for targeted drug delivery, e.g., pegylated liposomes. The method simplifies the attachment of targeting vectors to sterically stabilized liposomes. The present invention also provides a liposome composition comprising a compound of the formula and a compound of the formula Z-Y, wherein Z is any compound capable of binding to a cellular receptor, and X and Y are compounds which can interact with each other non-convalently, and wherein the substituents n, F1 and F2 are as provided in the specification.

Abstract: Rapidly disintegrating preparations containing at least one active pharmaceutical ingredient and at least one excipient can be obtained by a simple process in which at least the predominant part of the complete composition of the ingredients for the preparation to be produced is granulated, the resulting granules and, where appropriate, the remainder of the ingredients are shaped in the presence of liquid virtually without pressure, and the resulting shaped articles are dried.

Abstract: The present invention provides a dual release solid dosage form containing a first composition that releases a neuraminidase inhibitor, such as oseltamivir, zanamivir, or peramivir, in a controlled manner and a second composition that releases an H1 antagonist in a rapid and/or immediate manner. A wide range of H1 antagonist antihistamines, especially fexofenadine and loratadine, can be used in this device. Particular embodiments of the invention provide osmotic devices having predetermined release profiles. The device is useful for the treatment of respiratory congestion and other viral infection associated symptoms.

Abstract: A resorbable extracellular matrix for reconstruction of cartilage tissue includes a purified collagen II derived from natural cartilage tissue from which non-collagen proteins have been removed. The matrix can be utilized as a scaffold implant for meniscal or vertebral cartilage regeneration.

Abstract: The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target.

Abstract: This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one oligonucleotide. The composition may be further supplemented with, for example, one or more analgesics, antimicrobial compositions, anticoagulants, antiproliferatives, anti-inflammatory compounds, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like.

Abstract: The present invention relates to a method for the prevention and/or treatment of vascular disorders and/or secondary disorders associated therewith, such as depression. The method according to the invention comprises the oral administration of a preparation which contains at least the following fractions: a) long chain polyunsaturated fatty acids; b) at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine and c) one or more compounds which are a factor in methionine metabolism, which compounds are selected from the group consisting of folate, vitamin B12, vitamin B6, magnesium and zinc or equivalents thereof. The invention also relates to a preparation for oral dosage comprising: at least 120 mg of long chain polyunsaturated fatty acids; at least 200 mg phospholipids; at least 200 ?g folate; and at least 0.1 mg hypericin and/or at least 100 mg extract of Withania somnifera.

Abstract: Anthocyanins, other flavonoids and related polyphenolic compounds are extracted from fruits or highly pigmented garden vegetables and their by-products using subcritical water with or without a secondary cosolvent. This method has the advantages of being relatively inexpensive, minimizes or totally avoids the use of objectionable solvents, and provides a facile means for supplying an ample source of concentrated phytochemicals for use in food formulation, dietary supplements and phyto-pharmaceutical applications.

Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.

Abstract: The invention herein describes a procedure for organically extracting the lipophilic components from plants of the Family Euphorbaciae, specifically but not limited to the genus Croton. The extraction (CGO 110), is deplete of the normal proanthocyanidin content found in the parent material, yet retains its pharmacocological abilities and unlike the parent material, is selectively cytotoxic to cancer cells. The depletion of the proanthocyanidin components makes the product more amenable to preparations for the benefit of ameliorating both human and animal disease.

Abstract: A soft gelatinous food elastomer composition and article useful as fishing bait formed from one or a mixture of two or more of a thermoplastic elastomer block copolymers) and one or more plasticizers and a food or components of food.

Abstract: The invention relates to a novel confectionery product comprising a casing of a protective confectionery material and a filling enclosed within the casing, wherein the casing is configured to enable the filling to be released without the casing having to be substantially dissolved and; wherein the filling includes a major amount of monosaccharide polyol in a crystalline anhydrous powder form chosen among polyols having a cooling effect. Preferably, the filling represents 6 to 40% by weight of the product and includes xylitol, erythritol, sorbitol or a combination thereof.

Abstract: The present invention involves a novel chewing gum formulation and a method of making the same. The chewing gum formulation is used to form a final chewing gum composition which contains an active ingredient which is released from the chewing gum as the gum is masticated in the mouth of the user. The chewing gum made from the chewing gum composition of the present invention is initially a compressed body, such as a tablet, which quickly dissociates into a multiplicity of small pieces upon initial chewing followed by a reformation of the pieces into a coherent mass of chewing gum after a few seconds of chewing. Both the chewing gum formulation and the chewing gum composition are in the form of a free-flowing particulate which is capable of being directly compressed at high speed by a standard tableting machine into chewing gum tablets.

Abstract: Method for the control of a controlled atmosphere for the storage of plant products in at least one storage- or transport space, where a) the concentration of at least one trace gas that is produced by the plant products and has a share of less than 1% of the controlled atmosphere is measured at least twice at different times; b) the degree of change in the concentration of the trace gas is derived from at least two measuring values as the measure of the production rate of the plant product for said trace gas; c) the control variables for the composition in the controlled atmosphere are determined depending on the degree of change in the concentration of the trace gas, and d) the composition of the controlled atmosphere is adjusted according to the control variables.

Abstract: A molded dried food material which can be preserved at normal temperature, exhibits favorable rehydrating property with full of voluminous feeling when rehydrated, maintaining excellent taste, color and eat feeling without permitting the shape to be collapsed. A method of producing a dried food material comprises the steps of blanching a food material to be treated to obtain a blanched food material; mixing a vehicle to the blanched food material to obtain a vehicle-mixed food material; drying the vehicle-mixed food material with the hot air until the weight reduces to no less than 20% but no more than 70% to obtain a rehydration dried food material; press-molding the rehydration dried food material to obtain a press-molded food material; and freeze-drying the press-molded food material to obtain a freeze-dried food material; wherein the press-molding process to press down the freeze-dried food material with a force which can be rehydrated back to a sufficient degree when rehydrated.

Abstract: The invention describes the cost effective process for the preparation of a mixture of salts having low sodium salt (health salt) contain and exclusively derived from vegetable sources which have desired sodium chloride: potassium chloride ratio and traces of micronutrients including iodine, said salt is white in color and free flowing in nature.

Abstract: An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The method of loading beneficial agent includes dispensing beneficial agent in a raster format and/or an off-axis format along a dispensing path.

Abstract: A structure comprises a thermal energy generating component and a thermal dissipating device in thermal conductive contact with the component, the device comprising a substrate with a fullerene coating. A method of producing a computer comprises applying a layer of fullerene onto a substrate and disposing the substrate in a heat dissipation relationship to a microprocessor.

Abstract: Application of a thermally and/or electrically conductive compound to fill a thermal and/or EMI shielding gap between a first and a second surface. A supply of a fluent, form-stable compound is provided as an admixture of a cured polymer gel component, and a particulate filler component. An of the compound is dispensed from a nozzle or other orifice under an applied pressure onto one of the surfaces which, when opposed, form the gap, or into the gap formed between the surfaces. The gap is at least partially filled by at least a portion of the dispensed compound.

Abstract: A method for direct writing an electrically conductive metallic feature on an insulating substrate comprises creating a gas jet comprising metallic particles (301), ejecting the gas jet comprising metallic particles through a straight bore tube (302), and impacting the gas jet comprising metallic particles onto a substrate to impinge the metallic particles on the substrate to form the electrically conductive metallic feature (303).

Abstract: A film sheet which has a polymer layer formed of a coating solution is drawn from a balk roll and transported toward a rubbing apparatus. Thereby, first and second blowers sequentially disposed respectively apply to the polymer layer an air of temperature 45±2° C. and humidity 50%–60%, and an air of temperature 25±1° C. and humidity 30%–35%. Thus, damages which occurred in transporting and rolling the film sheet are removed. Thereafter, a rubbing action is performed to the film sheet such that the polymer layer has alignment. Then a liquid crystal layer is formed on the polymer layer, to obtain an optical compensation film.

Abstract: A method for depositing a thin film includes the steps of providing a vapor including at least one selected vapor phase component into an evacuated chamber and condensing the vapor onto a heated substrate to form a liquid phase deposit wherein a temperature of the substrate is lower than the condensation temperature of the component. The liquid deposit is then cooled to produce a solid phase film. The invention can provide two or more vapor phase components. The invention can be used to deposit a wide variety of layers, including thin films of metallic, semiconductor and nonmetallic inorganic materials. The invention is useful for forming solid electrolytes and the electrodes for batteries, fuel cells and other electromagnetically active devices.

Abstract: The present invention relates to oxides on suitable substrates, as converted from nitride precursors.

Abstract: A process for the deposition of copper on a support. The process includes bringing a copper precursor, in the vapor phase, into contact with a heated support, optionally in the presence of hydrogen. The copper precursor is in the form of a CuCl or CuBr composition in a nonaromatic, nonplanar and heteroatom-free liquid organic solvent which exhibits at least two nonconjugated unsaturations.

Abstract: The invention includes a chemical vapor deposition method of forming a barium strontium titanate comprising dielectric layer having a varied concentration of barium and strontium, and/or titanium, within the layer. A substrate is positioned within a chemical vapor deposition reactor. Barium and strontium are provided within the reactor by flowing at least one metal organic precursor to the reactor. Titanium is provided within the reactor. One or more oxidizers are flowed to the reactor. In one aspect, conditions are provided within the reactor to be effective to deposit a barium strontium titanate comprising dielectric layer on the substrate from the reactants.

Abstract: After displaying information (10) on the surface of an outer wall (4) of a cell structure, a portion surrounding the displayed information (10) is coated with a coating agent to form a region permeated with a coating agent (24) wherein pores (22) of the outer wall (4) are filled with the coating agent in a section of the outer wall (4) on which the information (10) is displayed. The region permeated with a coating agent (24) prevents a catalyst solution from exuding from the inside of the outer wall (4) of the cell structure. According to a method for protecting the displayed information and the cell structure of which surface information is protected by the protection method, a displayed information portion after loading catalyst components is prevented from being colored, and the displayed information can be maintained in a readable state.

Abstract: The present invention provides for a method of producing an integral multilayered porous membrane by simultaneously co-casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a porous membrane. The support can be a temporary support or form an integrated support for the membrane. The plurality of layers may be of the same polymer or different, same concentration or viscosity or different and may be subjected to the same processing conditions or different ones to form unique structures.

Abstract: A coating apparatus and coating method include a device for conveying an object to be coated; a coating device which is disposed in a vicinity of a conveyed surface of the object, and which discharges a coating liquid, and which forms a bridge of the liquid between the device and the object which is conveyed by the device for conveying an object to be coated, and which coats the liquid on at least one surface of the object; and a gas stream blowing device which, immediately after starting of coating, blows out a gas from a direction substantially opposite to a object conveying direction, toward a portion of the object where coating starts.

Abstract: A method of finishing a barrier fabric includes applying a non-aqueous solution of low surface tension solvent and fluorochemical repellent to a barrier fabric, subjecting the barrier fabric to conditions sufficient to remove the solvent from the barrier fabric, and applying an aqueous-based antistat to a surface of the barrier fabric. The low surface tension solvent substantially covers all fibers in the barrier fabric with the fluorochemical repellent. The antistat is prevented by the fluorochemical from migrating from the surface to which it is applied.

Abstract: According to the present invention, there is provided a method for forming a metal oxide film comprising, when a metal oxide film is formed by conducting a thermal treatment on a coating film containing an organic metal compound formed on an inner wall of a tube, performing an ultraviolet irradiation treatment or an ozone treatment on the coating film prior to or simultaneously with the thermal treatment.

Abstract: A method and apparatus for forming a thin film magnetic recording media, the method comprises generating magnetic nanoclusters from a target of magnetic material, crystallizing the magnetic nanoclusters, and depositing the magnetic nanoclusters onto a substrate to form a thin film of magnetic particles thereon. The magnetic nanoclusters are deposited onto the substrate after crystallized and therefore after the deposition. The apparatus comprises a first chamber, a second chamber connected to the first chamber, and a third chamber connected to the second chamber. The first chamber has a source for generating magnetic nanoclusters. The second chamber is to receive the magnetic nanoclusters and crystallize the magnetic nanocluster. The third chamber is to receive the crystallized magnetic nanoclusters from the second chamber and deposit the crystallized magnetic nanoclusters onto the substrate positioned therein.

Abstract: A film for a liquid crystal display comprising a fatty acid cellulose ester film having an acetyl group and a propionyl group is disclosed. Sum of degree of acetyl substitution (DSac) and degree of propionyl substitution (DSpr) of the fatty acid cellulose ester film of the film is 2.8 or less, and a retardation value (Rt value) in the thickness direction define by Formula 1 is 60 to 300 nm.

Abstract: A glass crack prevention laminate has a glass crack prevention adhesive layer having a dynamic storage elastic modulus G? of not larger than 1×107 Pa at 20° C., and a liquid crystal display optical film laminated on a surface of the glass crack prevention adhesive layer. Particularly, the liquid crystal display optical film is made of a polarizing plate or of a laminate of a polarizing plate and another optical layer. The thickness of the glass crack prevention adhesive layer is selected to be in a range of from 0.1 mm to 5 mm. The glass crack prevention adhesive layer has removability. The adhesive agent-including optical film having the configuration can be directly mounted on a liquid crystal panel so that the glass crack prevention adhesive layer is provided on an inner side. Thus, a liquid crystal display device can be provided.

Abstract: A liner for a high pressure gas container includes a resin composition containing a polyphenylene sulfide resin and an olefin based resin. The resin composition has a methane gas permeability coefficient of 1.7×10?16 mol·m/m2·s·Pa or smaller at 40° C., and tensile elongation of 50% or greater after fracture at 23° C. A high pressure gas container having such a liner is also provided.

Abstract: A floor mat includes a rectangular base section that has oppositely spaced edge portions and a planar top surface provided with surface indicia. The base section is formed from durable material to withstand inclement weather conditions. The floor mat further includes a plurality of thermochromic dyes for selectively displaying at least one footprint on the top surface such that the footprint automatically appears and disappears when a temperature of the top surface falls below and above a threshold temperature. A hand-operable actuator is included that has a cavity for holding a selected quantity of fluid therein. The actuator is slidably engageable with the top surface such that the top surface temperature can be regulated by the user.

Abstract: The invention teaches a container formed from a synthetic substrate. The synthetic substrate is substantially tear resistant and includes polyethylene and inorganic minerals. The synthetic substrate is cut and scored to form a container blank of desired shapes and sizes. At least some portion of the container blank is coated with an adhesive. The container blank is folded and or otherwise manipulated so that at least some portion of the container blank is secured to another surface of the container blank to form a partially closed container with at least one opening.

Abstract: A fuel container with high fuel barrier properties is provided. The fuel container is a coextrusion blow-molded fuel container having a container body made of a layered structure. The layered structure comprises: a barrier layer made of a barrier resin (A); and an inner layer and an outer layer made of a thermoplastic resin (B) that is different from the barrier resin (A); wherein a ratio (X/Y) of a distance (X) between end portions of the barrier layer at a pinch-off part of the fuel container and an average thickness (Y) of the container body is at least 1/10000 and at most 1/10; and wherein a ratio (Y1/Y) between a total thickness (Y1) of the layers of the container body that are located on the inside with respect to the barrier layer and an average thickness (Y) of the container body is at least 3/10 and at most 7/10.

Abstract: In an electrophotographic belt member comprising a resin composition, the resin composition contains from 30% by weight to 90% by weight of a thermoplastic resin, from 2% by weight to 30% by weight of a compound selected from the group consisting of a polyether-ester amide, a polyether ester and a polyether amide, from 0% by weight to 5% by weight of an electrolyte, and from 2% by weight to 50% by weight of an insulating filler. Also disclosed are a process for producing the electrophotographic belt member, and an electrophotographic apparatus having the electrophotographic belt member.

Abstract: A label applicator kit comprising a holder including first holding means for holding a first set of tabbed materials such that the tabs of the first set are staggered, exposed and in a first line and a second holding means for holding a second set of tabbed materials such that the tabs of the second set are staggered, exposed and in a second line that is parallel to and spaced from the first line. The holder being a pouch, the first holding means being a first pocket of the pouch and the second holding means being a second pocket of the pouch. The pouch being in a sets-holding condition when the first holding means is holding the first set and the second holding means is holding the second set.

Abstract: The invention relates to a molded decorative film that can be foam-backed and that is used in the passenger compartment of motor vehicles. Said decorative film is provided with a break line that is defined by a notched weakening in cross-section in the airbag penetration area. Said weakening in cross-section is formed by an internal notch that is closed at both ends by the material of the decorative film. Preferably, a notch is produced that extends on the side that can be foam-backed to the surface of the film and the notch is then closed on said side by welding.

Abstract: A honeycomb structural body having a plurality of cells and partition walls defining the cells, wherein a cross-section of each partition wall perpendicular to the flow direction of a fluid to be permeated has a grille shape of which gratings cross in x axis and Y axis directions, and there are at least two kinds of cells different in their cross-sectional areas perpendicular to the flow direction of a fluid to be filtered by virtue of changing intervals of the partition walls in the x axis direction and/or intervals of the partition walls in the y axis direction, as predetermined. Each cell is defined by two parallel partition walls having the same length and another two parallel partition walls having the same length crossing each other and being formed at the predetermined intervals. A die usable for forming such a honeycomb structure is also disclosed.

Abstract: A reusable, air-permeable packaging film formed of a layer of resilient and nontoxic material is disclosed. The packaging film includes a plurality of micro-gaps distributed within a pre-selected area on the packaging film, wherein each of the micro-gaps traverses thickness of the packaging film, and wherein, in a static state, i.e., no pressure/stress exerted on the packaging film, each of the micro-gaps comprises a split upper seam portion with edge ridges demonstrated on a top surface of the packaging film and a close lower seam portion communicating with the split upper seam portion. During microwaving, the pressure can be regulated at a relatively lower vapor transferring rate through the pre-selected area.

Abstract: A disposable cutting sheet for cutting and preparation of food items thereon includes a first cut resistant layer having an absorbent ply and a thermoplastic ply, wherein the thermoplastic ply includes a plurality of apertures therethrough. The sheet further includes a second liquid impervious layer including an absosrbent ply and a thermoplastic ply, wherein the absorbent ply of the second layer is disposed below and secured to the absorbent ply of the first layer. The cutting sheet further includes a score line disposed across the substrate for separating the cutting sheet into two portions, wherein the score line extends fully through the cutting sheet near edges of the cutting sheet to create a tear notch. The score line extends through the thermoplastic ply of the cut resistant layer in an area of the cutting sheet between the edges thereof.

Abstract: An article having a top sheet, a core layer and, optionally, a barrier layer is configured to provide storage and metered release of a highly viscous fluid to a target surface. The core layer contains an array of three dimensional voids, which may be opened (i.e., apertured) or closed, that are configured to receive and store the fluid, and is formed of a material that is non-absorbent with respect to the fluid.

Abstract: A method of providing a resistance to oxidation of Nickel at high temperatures by combining Ni powder with five percent Pt resinate, and heating the same to a temperature of 500° C. to 1300° C. Electro-conductive components serving as electrodes and the like comprise a Ni/Pt powder subjected to temperatures of between 500° C. and the respective melting points of Ni and Pt.

Abstract: A system and method for forming an article from thermoplastic material and fiber. The method includes heating thermoplastic material to form a molten thermoplastic material for blending with the fiber. The molten thermoplastic material is blended with the fibers to form a molten composite material having a concentration of fiber by weight. The molten composite material may then be extruded through dynamic dies to deliver discrete controlled material that is gravitated onto a lower portion of a mold. The lower portion of the mold may be moved in space and time while receiving the flow of composite material to deposit a predetermined quantity of molten composite material thereon conforming to mold cavities of the lower and an upper portion of the mold. The upper portion of the mold may be pressed against the predetermined quantity of molten composite material and closing on the lower portion of the mold to form the article.

Abstract: A fiber-reinforced composite material including reinforcing fibers and a matrix resin, wherein at least some of the reinforcing fibers have their ends in the matrix resin, and a second resin having an elastic modulus less than that of the matrix resin is present in contact with fiber ends of at least some of reinforcing fibers having above-mentioned ends and only in the neighborhood thereof.

Abstract: A Sheet Molding Compound (SMC) as prepregs and cured compositions with naturally derived fibers which have been dried for at least three hours is described. The SMC process combines polyester polymer or resin with the fibers preferably continuously. The molded products are useful for a variety a purposes where glass fiber filled polyester polymers are conventionally used.

Abstract: A porous structure having a plurality of bonded sheets each sheet having at least one aperture that partially overlaps an aperture of at least one other sheet. A method of producing a porous structure including stacking a plurality of sheets each sheet having a multiplicity of apertures, and bonding each sheet to its adjoining sheet. An open-pore network structure having a multiplicity of sheets each having a repeatable pattern. At least a portion of each sheet is bonded to the web of an adjacent sheet. The porous area of at least one of the sheets is askew to the porous area of at least another of the sheets. An open-pore structure having a multiplicity of bonded sheets, each sheet having a repeatable pattern defining a multiplicity of perforations, and a plurality of apertures defined by the repeatable pattern, the apertures extending through the perforations of at least two adjacent plates.