Abstract: A crystallization mask for laser illumination for converting amorphous silicon into polysilicon is provided, which includes: a plurality of transmissive areas having a plurality of first slits for adjusting energy of the laser illumination passing through the mask; and an opaque area.

Abstract: A method for forming micropatterns includes forming a thin film consisting of a single layer or of plural layers on a substrate, irradiating an energy beam to the thin film to elevate the temperature of a region to a predetermined temperature or higher to thereby modify the region of the thin film, and patterning the thin film at least in such a manner to leave over the modified region.

Abstract: Single-layer and multilayer imageable elements have a substrate and at least one imageable layer and can be used to prepare positive-working lithographic printing plates. The imageable elements also include a radiation absorbing compound and a solvent-resistant polymer binder comprising an —N(R)—C(?X)—N(R?)—S(?O)2— moiety that is attached to the polymer backbone, wherein X is O or S, R and R? are independently hydrogen, halo, or an alkyl group having 1 to 6 carbon atoms. This solvent-resistant polymer binder is located in the imageable layer closest to the substrate and provides improved chemical resistance.

Abstract: A photoconductive imaging member comprised of a supporting substrate, and thereover a single layer comprised of a mixture of a photogenerator component, charge transport components, and a certain electron transport component, and a certain polymer binder.

Abstract: The toner for developing an electrostatic image, includes a toner particle containing a binder resin and a colorant. The colorant has Feret's average horizontal diameter from 10 nm to 500 nm, and 50 number % or more of colorant has a Feret's horizontal diameter of from 2 nm to 300 nm.

Abstract: In the toner comprising at least a colorant, a releasing agent and a binder resin, the releasing agent being a mixture of carnauba wax and non-paraffin wax, the binder resin contains a polyester resin comprising a cyclohexane dimethanol of a polyhydric alcohol ingredient as an essential ingredient and having an acid value of 5 to 20 mg KOH/g. An electrophotographic negatively charged full color toner having good fixing property, glossiness, transparency, and releasability without coating a fixing oil to a fixing apparatus.

Abstract: A method for producing a toner including dissolving or dispersing a toner constituent mixture including a binder resin and a colorant in an organic solvent to prepare a toner constituent mixture liquid; dispersing the toner constituent mixture liquid in an aqueous medium including a particulate dispersant to prepare an emulsion; and removing the organic solvent from the emulsion while applying a shearing force to the emulsion. A toner manufactured by the method and having a spindle form while satisfying specific particle diameter relationships. An image forming apparatus using the toner. A toner packing method and device in which the toner is fluidized and pressurized to be fed from a fluidizing container to a toner container on which a gas-powder separation sieve is set to discharge air therefrom.

Abstract: The present invention relates to a developer carrying member for carrying a developer having at least a substrate and a resin-coated layer formed on the surface of the substrate. The developer carrying member is the one which carries a one-component developer to visualize the electrostatic latent image carried by the electrostatic latent image carrying member, the resin-coated layer contains at least a binder resin, graphitized particles and roughing particles, the graphitized particles has 0.20 to 0.95 of graphitization degree (p (002)), and wherein in the surface configuration of the resin-coated layer as measured by use of focusing optical laser, the volume (B) of a microtopographical region defined by a certain area (A) of the microtopographical region without convexity formed by the roughing particles meets the following relationship 4.5?B/A?6.5, and the resin-coated layer has 0.9 to 2.5 ?m of arithmetic mean roughness (Ra).

Abstract: The present invention relates to a process for increasing the level of safeguard in respect of forgery of paper documents. For that purpose, applied to the paper document is a transfer film or laminating film having a laser-sensitive layer. This multi-layer body is then treated with laser radiation. In that case, a laser-induced marking is produced in the laser-sensitive layer, for example, by laser-induced bleaching, laser-induced color change or laser-induced blackening. Respective individualization of the document can be effected by way of that laser-induced marking.

Abstract: A thermal transfer image receiving sheet comprising a heat insulating layer and a layer adjacent to the heat insulating layer on a substrate, wherein the heat insulating layer is provided between the layer and the substrate, the heat insulating layer contains hollow particles in an amount of at least 65 percent by mass, and the heat insulating layer and the layer are formed by simultaneous multi-layer coating.

Abstract: A method of fabricating a donor substrate and a method of fabricating an organic light emitting display (OLED) using the donor substrate. The method of fabricating the donor substrate includes preparing a base substrate that includes at least one transfer region and at least one non-transfer region, forming a light-to-heat conversion layer on the base substrate and depositing a transfer layer selectively on the light-to-heat conversion layer and in the at least one transfer region of the base substrate using a shadow mask. To then make the OLED, laser induced thermal imaging is used to transfer the patterned transfer layer from the donor substrate to display regions in an acceptor substrate.

Abstract: Substrate films, thermal mass transfer donor elements, and methods of making and using the same are provided. In some embodiments, such substrate films and donor elements include at least two dyads, wherein each dyad includes an absorbing first layer and an essentially non-absorbing second layer. Also provided are methods of making a donor element that includes an essentially non-absorbing substrate, an absorbing first layer, and a non-absorbing second layer, wherein the composition of the essentially non-absorbing substrate is essentially the same as the composition of the essentially non-absorbing second layer.

Abstract: A positive type photoresist composition suitable for light in the wavelength region of 170 nm to 220 nm, high in sensitivity, excellent in adhesion and giving a good resist pattern profile, which comprises a resin having an ester group represented by the following general formula [I] in its molecule and a compound generating an acid by irradiation of an active light ray or radiation: wherein R1 represents a hydrogen atom, an alkyl group or a cycloalkyl group; and R2 and R3, which may be the same or different, each represents a hydrogen atom, an alkyl group, a cycloalkyl group or -A-R4, and R2 and R3 may combine together to form a ring, wherein R4 represents a hydrogen atom, an alkyl group or a cycloalkyl group, R4 and R2 or R3 may combine together to form a ring, and A represents an oxygen atom or a sulfur atom.

Abstract: Compositions and techniques for the processing of semiconductor devices are provided. In one aspect of the invention, an antireflective hardmask composition is provided. The composition comprises a fully condensed polyhedral oligosilsesquioxane, {RSiO1.5}n, wherein n equals 8; and at least one chromophore moiety and transparent moiety. In another aspect of the invention, a method for processing a semiconductor device is provided. The method comprises the steps of: providing a material layer on a substrate; forming an antireflective hardmask layer over the material layer. The antireflective hardmask layer comprises a fully condensed polyhedral oligosilsesquioxane, {RSiO1.5}n, wherein n equals 8; and at least one chromophore moiety and transparent moiety.

Abstract: Compositions and methods of use thereof are disclosed. One exemplary composition, among others, includes a polymer resin and a photoacid generator. In particular, the composition includes a polymer resin, wherein the polymer resin does not substantially absorb about 1 to 450 nanometer (nm) wavelength energy; and a photoacid generator, wherein the photoacid generator does substantially absorb about 1 to 450 nanometer (nm) wavelength energy.

Abstract: Imaging compositions and methods of using the compositions are disclosed. The imaging compositions are sensitive to low levels of energy such that upon application of the low levels of energy the compositions change color or shade. The compositions may be applied to a work piece to mark it and removed from the work piece by peeling.

Abstract: The present disclosure relates to a limited play optical storage media and a method for limiting access to data thereon. This storage media includes a first substrate; a reflective layer; a data storage layer disposed between said first substrate and said reflective layer; a reactive layer comprising at least one reactive material disposed on said at least one reflective layer; an optically transparent second substrate disposed between the reactive layer and a laser incident surface of the optical storage media; and an oxygen permeable barrier layer disposed between the reactive layer and a laser incident surface of the optical storage media, said reactive layer having an initial percent reflectivity of about 50% or greater and a percent reflectivity of about 45% or less after exposure to oxygen.

Abstract: Squarylium-metal chelate compounds as recording materials for optical recording media, and optical recording media using these compounds, which have excellent recording properties, light resistance and storage stability. The squarylium-metal chelate compound is represented by following Structural Formulas (1) and (2): In the formula (1), M represents a metal atom capable of coordinating; “a”, “b” and “c” each represents a squarylium dye ligand of formula (2), where “a” is different from “b”; and “c” may be the same as or different from “a” or “b”; and “m” represents 0 or 1. In the formula (2), R1 and R2 are the same or different and each represents an alkyl group, aralkyl group, aryl group or heterocyclic group, each of which may be substituted; and X represents an aryl group which may be substituted, a heterocyclic group which may be substituted, or Z3=CH—, wherein Z3 represents a heterocyclic group which may be substituted.

Abstract: It is an object of the present invention to provide that printing plate materials of the present invention exhibit excellent printing durability, less “out of color” registration, and improved printing image quality. Disclosed is a printing plate material possessing an image formation layer on one surface of a polyester support and not less than two backing layers on the other surface, wherein at least one of the backing layers is an electrically conductive layer, at least one of the backing layer is a layer containing at least one resin selected from polyester resin, acryl resin, acryl modified polyester resin and cellulose ester resin provided on the electrically conductive layer, and at least one of the backing layers contains an organic matting agent.

Abstract: A method is provided for simulating and/or demonstrating and/or enhancing photoactive properties, such as hydrophilicity, of a surface, such as a photoactive surface. One embodiment includes providing a photoactive surface and applying a peroxide-containing material, such as an aqueous hydrogen peroxide solution, over at least a portion of the surface. An optional resinous layer, such as an at least partly hydrolyzed polymethoxysiloxane layer, can be applied over the surface. A kit to practice the method and an article made using the method are also provided.

Abstract: In a laser-engravable flexographic printing element, the relief-forming layer comprises a conductivity carbon black having a specific surface area of at least 150 m2/g and a DBP number of at least 150 ml/100 g. Flexographic printing plates are produced by a process in which a printing relief is engraved into said flexographic printing element by means of a laser system.

Abstract: A process for generating a hard mask for the patterning of a first layer includes applying a second layer, which includes carbon, to the first layer that is to be patterned. A third layer, which includes silicon and carbon, is spun onto the second layer and an organic antireflection coating layer that is to be used with an overlying photoresist layer patternable using 193 nm technology, is appllied to the spun-on third layer.

Abstract: A method of forming an integrated circuit using an amorphous carbon film. The amorphous carbon film is formed by thermally decomposing a gas mixture comprising a hydrocarbon compound and an inert gas. The amorphous carbon film is compatible with integrated circuit fabrication processes. In one integrated circuit fabrication process, the amorphous carbon film is used as a hardmask. In another integrated circuit fabrication process, the amorphous carbon film is an anti-reflective coating (ARC) for deep ultraviolet (DUV) lithography. In yet another integrated circuit fabrication process, a multi-layer amorphous carbon anti-reflective coating is used for DUV lithography.

Abstract: An immersion lithography process is described. First, a photoresist layer on a material layer is formed. Then, an acid compensation layer is formed on the photoresist layer. An immersion exposure step is performed on the acid compensation layer and the photoresist layer. The acid compensation layer contains a photo-acid generator with a concentration of the photo-acid higher than that produced by a photo-acid generator in the photoresist layer after the immersion exposure step. Then, a development step is performed to pattern the acid compensation layer and the photoresist layer.

Abstract: The present invention provides a photothermographic material having, on at least one side of a support, at least an image forming layer containing a photosensitive silver halide, a non-photosensitive organic silver salt, and a reducing agent for the organic silver salt, and at least one non-photosensitive layer, wherein the material contains a water-soluble magenta dye, and also provides an image forming method.

Abstract: A silver halide light-sensitive photographic element comprising a support having on one side thereof at least one cyan image forming hydrophilic colloid layer comprising a cyan image dye forming coupler, and an outermost protective overcoat layer providing a coefficient of friction of less than 0.20 after standard ECP-2B processing, wherein the ratio of permanent solvent to coupler in the cyan image forming layer is less than 0.8.

Abstract: The invention relates to a photographic element comprising a support and at least three color records comprising at least three light sensitive layers and at least two interlayers, wherein the light sensitive layers include cyan, magenta, or yellow dye-forming coupler, the light sensitive layers include silver halide grains comprising greater than 90% silver chloride, scavengers are included in the interlayers, the ratio of the total level of scavenger to the total level of coupler is from 0.15 to 0.50, the ratio of the total level of scavenger to the total level of silver is from 0.05 to 0.15, and the reciprocity characteristics of the silver halide grains are such that for a separation exposure of 1 microsecond and 0.4 seconds, upon development, the difference in maximum density is 10% or less and a method for processing the element comprising color developing the element for less than 30 seconds.

Abstract: The invention provides a photothermographic material containing, on a support, an image forming layer having at least a photosensitive silver halide, a non-photosensitive organic silver salt and a reducing agent, and at least one non-photosensitive layer, in which the non-photosensitive layer contains a crosslinking agent precursor, in which the crosslinking agent precursor is a compound which releases a crosslinking agent which crosslinks a binder of the non-photosensitive layer at the time of thermal development. A photothermographic material in which water resistance and scratch resistance of an image have been improved is provided.

Abstract: The invention relates to a blood-compatible surface comprising a polymer surface and a plurality of conjugates made of linkers and active agents immobilized thereon. The polymer surface contains similar or different structural units that carry carbonyl groups. The linkers contain a structural element that is able to form a hydrogen bridge bond. A polyorganosiloxane acting as the active agent is linked to the linkers.

Abstract: The present invention makes available a rapid, reproducible, robust assay system for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular protein, e.g., a receptor or ion channel. The subject assay enables rapid screening of large numbers of compounds to identify those which act as an agonist or antagonist to the bioactivity of the cellular protein. In this system, the cell is treated with a compound, and functional interaction of this compound with a cellular receptor yields a detectable signal, which can be specifically measured. The subject assays include methods of identifying compounds which specifically modulate, for example, heterologous receptors coupled to the pheromone response pathway in yeast. The subject assays are particularly amenable to the identification of specific agonists and antagonists of G protein-coupled receptors.

Abstract: A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a masking process.

Abstract: Synthetic peptides immunoreactive with hepatitis A virus (HAV) antibodies are provided. The peptides are useful as laboratory reagents to detect or quantify HAV antibodies in biological samples in clinical or research-based assays and for inducing an immune response to HAV when administered to a human or animal. The peptides contain antigenic epitopes, modified antigenic epitopes or combinations of epitopes of the major structural capsid polypeptides or non-structural polypeptides of HAV and contain one or more molecules of the amino acid glutamine (Q) at the carboxyl end of the peptide, which enhances immunoreactivity and immunogenicity, particularly IgM antibody reactivity.

Abstract: The present invention provides methods for detecting and identifying sequence variations in a nucleic acid sequence of interest using a detector primer. It has been found that the reduced efficiency of primer extension by DNA polymerases when the 3? end of a primer does not hybridize perfectly with the target can be adapted for use as a means for distinguishing or identifying the nucleotide in the target which is at the site where the diagnostic mismatch between the detector primer and the target occurs. The detector primer hybridizes to the sequence of interest and is extended with polymerase. The efficiency of detector primer extension is detected as an indication of the presence and/or identity of the sequence variation in the target. The inventive methods make use of nucleotide mismatches at or near the 3? end of the detector primer to discriminate between the nucleotide sequence of interest and a second nucleotide sequence which may occur at that same site in the target.

Abstract: Methods and compositions for detecting molecular interactions, particularly protein-protein interactions, are provided. The invention allows detection of such interactions in living cells or in vitro. Detection of molecular interactions in living cells is not limited to the nuclear compartment, but can be accomplished in the cytoplasm, cell surface, organelles, or between these entities. In one embodiment, the method utilizes novel compositions comprising fusion proteins between the molecules of interest and two or more inactive, weakly-complementing ?-galactosidase mutants. Association between the molecules of interest brings the complementing ?-galactosidase mutants into proximity so that complementation occurs and active ?-galactosidase is produced. The active ?-galactosidase may be detected by methods well-known in the art. Among the uses of the invention are the study of protein-protein interactions, functional genomics, agonist and antagonist screening and drug discovery.

Abstract: An assay is provided for nucleic acids that can be post-synthetically labeled, wherein modified nucleoside triphosphates are used that are more efficiently and specifically incorporated during nucleic acid synthesis than labeled nucleoside triphosphates. In a preferred embodiment, nucleoside ?-thiotriphosphates are utilized. Maleimide or iodoacetamide conjugating moieties can be attached post-synthetically. The conjugating moieties may include a reporter group. Also disclosed are new methods for detecting single nucleotide polymorphism.

Abstract: The invention provides a highly efficient, rapid, and cost effective method of linking nucleic acid components in a predetermined order to produce a nucleic acid multicomponent construct. The invention further provides nucleic acid components, each nucleic acid component comprising a double stranded nucleic acid molecule having at least one single stranded 5? or 3? terminal sequence, the terminal sequence having sufficient complementarity to either a terminal sequence in a separate nucleic acid component or to a sequence in a linking nucleic acid molecule so as to allow for specific annealing of complementary sequences and linkage of the components in a predetermined order. Kits containing reagents required to practice the method of the invention are also provided.

Abstract: Devices for detecting a transient electrical signal in a sample are provided. Also provided are systems that include the subject devices. The subject devices and systems find use in a variety of applications, particularly in the characterization of a sample, and more particularly in the characterization of molecular entities in the sample.

Abstract: The present invention relates to improved methods of detecting a target using a labeled substrate or substrate analog. The methods comprise reacting the substrate or substrate analog in an enzyme-catalyzed reaction which produces a labeled moiety with independently detectable signal only when such substrate or substrate analog reacts. The present invention, in particular, describes methods of detecting a nucleic acid in a sample, based on the use of terminal-phosphate-labeled nucleotides as substrates for nucleic acid polymerases. The methods provided by this invention utilize a nucleoside polyphosphate, dideoxynucleoside polyphosphate, or deoxynucleoside polyphosphate analogue which has a colorimetric dye, chemiluminescent, or fluorescent moiety, a mass tag or an electrochemical tag attached to the terminal-phosphate. When a nucleic acid polymerase uses this analogue as a substrate, an enzyme-activatable label would be present on the inorganic polyphosphate by-product of phosphoryl transfer.

Abstract: Described is a gene and its encoded secreted tumor antigen, termed 36P6D5, and to diagnostic and therapeutic methods and compositions useful in the management of various cancers which express 36P6D5, particularly including cancers of the bladder, kidney, prostate, breast, colon, ovary and pancreas.

Abstract: The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.

Abstract: The present invention relates to the design and use of nucleic acid molecules to create novel materials. The present invention further relates to the use of DNA as a bulding block for DNA-materials that are of high yield and purity and that can be incorporated into larger structures.

Abstract: Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The present invention provides methods, compositions, and systems for synthesizing, selecting, amplifying, and evolving non-natural molecules based on nucleic acid templates. The sequence of a nucleic acid template is used to direct the synthesis of non-natural molecules such as unnatural polymers and small molecules. Using this method combinatorial libraries of these molecules can be prepared and screened. Upon selection of a molecule, its encoding nucleic acid template may be amplified and/or evolved to yield the same molecule or related molecules for re-screening. The inventive methods and compositions of the present invention allow for the amplification and evolution of non-natural molecules in a manner analogous to the amplification of natural biopolymer such as polynucleotides and protein.

Abstract: There is provided a method and kit for measuring the amount of an objective constituent contained in a specific lipoprotein in a biological sample such as serum and plasma, specifically for measuring the amount of cholesterol contained in high density lipoprotein, which can be applicable to clinical tests.

Abstract: Novel polypeptides having functional domains of interest are described, along with DNA sequences that encode the same. A method of identifying these polypeptides by means of a sequence-independent (that is, independent of the primary sequence of the polypeptide sought), recognition unit-based functional screen is also disclosed. Various applications of the method and of the polypeptides identified are described, including their use in assay kits for drug discovery, modification, and refinement.

Abstract: The invention relates to assays for screening for chemicals which affect the binding between proteins comprising an SH3 binding motif (such as Proline-rich Nuclear Receptor Co-regulatory protein (PNRC)) and nuclear receptor proteins. Compounds which affect the binding of PNRC to nuclear receptors can affect the expression of genes whose expression is under the control of nuclear receptors to which PNRC binds. PNRC interacts with the orphan receptors SF1 and ERR?1 in a ligand-independent manner and interacts with the ligand-binding domains of nuclear receptors such as ER, AR, PR, TR, BAR, and RXR in a ligand-dependent manner. A 23-amino acid region in the carboxy-terminal proline-rich region which contains an SH3-binding motif is sufficient for the interaction with nuclear receptors.

Abstract: The invention provides monoclonal antibodies that selectively bind to ectodermally- and endodermally-derived stem cells and methods for the diagnosis of a neoplasm in a subject by contacting a tissue sample from the subject with the antibodies. Also disclosed are methods for isolating such stem cells from a heterogeneous cell population by contacting the population with antibodies which selectively bind to stem cells.

Abstract: A biosensor for the identification of olfactants, including chemical and biological agents, prefumery, explosives and pharmaceuticals. The biosensors comprise robust eukaryotic cells, such as yeast, into which at least one exogenous olfactory signaling pathway has been genetically integrated to detect molecules of interest.

Abstract: Binding assays for identifying ligands that modulate human T1R3 polypeptide-associated taste are disclosed. These assays detect the specific binding of compounds to a human T1R3 polypeptide or the modulation of the specific binding of another compound that specifically binds human T1R3 polypeptide. The binding assays may include the use of detectable labels, e.g., radionuclides, enzymes, fluorophores, and the like. Compounds identified in these binding assays have potential application as T1R3 taste modulators and therefore potentially are useful additives in compositions for human or animal consumption.

Abstract: Diagnostic tests for characterizing an individual's risk of developing or having a cardiovascular disease. In one embodiment the present diagnostic test comprises determining the level of myeloperoxidase (MPO) activity in a bodily sample obtained from the individual or test subject. In another embodiment, the diagnostic test comprises determining the level of MPO mass in a bodily sample obtained from the test subject. In another embodiment, the diagnostic test comprises determining the level of one or more select MPO-generated oxidation products in a bodily sample obtained from the test subject. The select MPO-generated oxidation products are dityrosine, nitrotyrosine, methionine sulphoxide or an MPO-generated lipid peroxidation products.

Abstract: Immunoassays for the detection of everolimus are provided. Compounds for producing antibodies for everolimus, as well as antibodies produced therefrom, are also provided.