Abstract: A device to protect surgical tables that incorporates a horizontal base and a vertical flange that meet creating a vertex, where the vertex may have a radius. The horizontal base is supported by at least one foot providing a stable platform for the surgical table guard. The vertical flange is spaced away from the vertical base of the surgical table providing adequate clearance to the vertical base to allow the vertical base to compress in normal operation.

Abstract: A femur support assembly attachable to a surgical table. The support assembly is comprised of a support plate, and an elongated rod reciprocally movable in a generally vertical direction relative to the support plate. An elongated support is mounted to the rod. The elongated support is rotatable about the rod and has a plurality of like apertures formed thereon. Each of the apertures defines a mounting position. A femur hook is provided having an end dimensioned to be received in one of the plurality of apertures.

Abstract: A coffin made of a wood material, rather than being painted or finished, is temporarily covered with an attractive removable film for display purposes. The film is removed and recycled before the coffin is cremated or buried. This minimizes environmental contamination during both construction of the coffin and its disposal.

Abstract: A memorial urn includes a central core having at least one vessel stored therein, the vessel functioning to house and identify cremated remains. A protective outer shell having a one or more commemoratory items is positioned about the core. One or more lighted elements illuminates the outer body, and a candleholder is positioned onto the outer body. A base unit is removably secured to the bottom of the outer shell.

Abstract: A universal haptic drive system for arm and wrist rehabilitation that includes a hand accessory and a vertical handle for carrying the hand accessory, the vertical handle being movable in a transversal plane. The system furthermore includes a haptic actuator system for applying a force to the vertical handle. The vertical handle includes a universal joint with locking ability. When the universal joint is unlocked, it enables movements for wrist rehabilitation, and when it is locked it causes a stiff substantially vertical handle enabling movements for arm rehabilitation.

Abstract: A walker/cane assembly, multi-legged cane, and single-pointed cane may share common parts that may be easily connected and detached to allow a user to convert a walker/cane assembly to a multi-legged cane and/or a single-pointed cane. Accordingly, a user may use a single assembly that may be quickly and easily modified to meet the user's needs, such as his/her current balance or energy level. One or more folding mechanisms may be employed to allow the walker/cane assembly, or the frame forming a portion of the walker/cane assembly, to be easily collapsed and folded. This may allow a user to store the walker/cane assembly, or the frame portion of the assembly, in a smaller amount of space than the expanded walker/cane assembly or the frame portion of the assembly may otherwise occupy.

Abstract: A waterproof hand-held electric breast massager includes a casing, a driving motor, a power supply element and a massaging member. The sealing cover is disposed at one end of the tubal body and at least one a protrusion at another end of the tubal body. The bottom body further has a conductive sheet, and at least one a positioning slot around a hollow portion of the bottom body. When the positioning slot of the bottom body is aligned with the protrusion, the bottom body can be inserted into the tubal body. The driving motor is mounted in the tubal body, and the driving motor has a first and a second conductive parts. The first conductive part and the conductive sheet make contact with each other. The massaging member has a bowl-like shape and a lip with an elastic curved surface at a circumference edge such that the casing is disposed perpendicular with the lip of the massaging member.

Abstract: Disclosed are methods for marking a pharmaceutical product, container or pharmaceutical packaging system with a scent to establish the identity and/or source of the pharmaceutical.

Abstract: The device (1) according to the invention aims to join at least two medicine capsules (A, B) by adhesive bonding in a reliable and economical manner, in particular in the context of industrial production. To do this, this device comprises at least one matrix (10), which at least partially delimits a recess (15), for depositing capsules (Eight, B), and also a chamber (16), this recess and this chamber being separated from each other by a deformable wall (14) of the matrix, which matrix is designed to move elastically, by pneumatic action of its chamber (16), from a first configuration, in which its recess (15) receives the capsules with a glue (Z) interposed between them, to a second configuration, in which its deformable wall (14) at least partially envelops the capsules by flexible deformation, in such a way as to at least partially enclosed these capsules between the deformable wall and a bottom of the recess in order to align them and press them against one another.

Abstract: A pocket-sized blister-pack case, designed to receive a blister pack of a known type with a plurality of cells each containing a product, for example a pharmaceutical product in the form of a pill or tablet, has a plurality of capacitive and/or optical sensors for counting and displaying the number of pills that are taken out of the respective cell, as likewise the date and time of when they were taken, and is able to communicate via a packet mobile-radio interface the data to an authorized remote control centre that can check the degree of compliance of the patient to the therapy prescribed and can dialogue with the patient himself via packet and/or circuit mobile-radio interface.

Abstract: In an embodiment, the device comprises a stainless steel container portion, a stainless steel annular portion, and a silicone mouthpiece portion. Fluid or other contents stored in the device only come in contact with the stainless container portion, the stainless steel annular portion, and the silicone mouthpiece portion. The stainless steel container portion, the stainless steel annular portion, and the silicone mouthpiece portion all do not contain plastic, therefore the fluid in contact with these surfaces is not exposed to any toxins or other compounds found in plastic and therefore the leaching of plastic toxins and compounds cannot occur while the fluid is stored in the device. The mouthpiece portion can be any of a number of different varieties, sizes and shapes.

Abstract: An enteral pump system for delivering medical fluids unidirectionally includes a disposable fluid delivery set having a repeatable compression portion and an enteral feeding pump. The repeatable compression portion is helically coiled around a central axis to define a cylindrical shape. The compression portion is configured to pump a large volume of medical fluids per stroke. The compressing portion includes at least two adjacent tubing walls joined around the central axis for repeatable compression. The enteral feeding pump is configured to repeatedly and reliably compress the compression portion of the fluid delivery set along the central axis. In operation, the compression portion is repeatably compressed without distortion along the central axis by the enteral feeding pump to flow unidirectionally through the fluid delivery set.

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

Abstract: An article that is a porous, dissolvable solid structure that dissolves easily due to the shape, product orientation and/or method of manufacturing the porous, dissolvable solid structure. The process of making the Article involves preparing a pre-mixture, aerating the pre-mixture, dosing the pre-mixture into individual cavities in molds, and drying the pre-mixture to an Article having an open celled foam with a % open cell of from about 80% to about 100%.

Abstract: The present invention thus relates to a solid composition, in particular in the form of a loose or compact powder, comprising, in a cosmetically acceptable medium: a) at least one pulverulent phase; b) at least one lipophilic organic UV screening agent characterized in that the pulverulent phase comprises at least aerogel particles of hydrophobic silica exhibiting a specific surface per unit of weight (SW) ranging from 200 to 1500 m2/g, preferably from 600 to 1200 m2/g and better still from 600 to 800 m2/g, and a size, expressed as volume-average diameter (D[0.5]), of less than 1500 ?m and preferably ranging from 1 to 30 ?m, more preferably from 5 to 25 ?m, better still from 5 to 20 ?m and even better still from 5 to 15 ?m. It also relates to a cosmetic method for caring for and/or making up human keratinous substances, in particular the skin of the body or of the face or the hair, comprising at least the application, to the surface of the keratinous substance, of at least one composition as defined above.

Abstract: The present invention relates to quinone direct dyes of formula (I) below, organic or mineral acid or base salts thereof, tautomeric forms, optical isomers or geometrical isomers thereof and/or solvates thereof: and also to the use thereof for dyeing keratin fibers, in particular human keratin fibers such as the hair. The invention also relates to a composition for dyeing keratin fibers, comprising such direct dyes in a suitable dyeing medium. Similarly, a subject of the present invention is a process for dyeing keratin fibers, using the said dye composition.

Abstract: The present invention relates to bleaching composition for keratin fibres, especially human hair, comprising at least one compound with bleaching and/or highlighting effect and a specific chelating agent. The object of the present invention is a substantially water free bleaching and/or highlighting composition for keratin fibres, especially human hair, comprising at least one compound with bleaching and/or highlighting effect and a polyhydroxy carboxylic acid and/or its salt as a chelating agent. Suitable and most preferred is gluconic acid and its salts especially mono valent cation salts such as sodium, potassium and ammonium salts.

Abstract: Present invention relates to an aqueous oxidizing composition with improved stability. The object of the present invention is an aqueous composition comprising at least one oxidizing agent, salicylic acid and/or its salts and either acetaminophen or oxyquinoline and/or its salts and having a pH between 1 and 5.

Abstract: The invention relates to the use of specific heterocyclic couplers which are 7-amino-1,2,3,4-tetrahydroquinoline derivatives of formula (I) for dyeing keratin fibers such as the hair in which formula (I): R1 to R6, Ra to Rc and X are as defined in the description.

Abstract: A cosmetic composition according to the present invention may prevent the precipitation of caffeine at a low temperature, and thus may comprise a high concentration of caffeine that is effective in promoting lipolysis. Caffeine is known to promote lipolysis when applied to a human body. The cosmetic composition of the present invention may comprise a high concentration of caffeine, and thus can be valuably use in cosmetics or the like that requires effects of caffeine such as slimming effects, effect of relief from facial swelling or the like.

Abstract: Disclosed are compositions and methods for their use that can be used in cosmetic applications. The composition can include an effective amount of a Centella asiatica stem cells to reduce the activity of hyaluronidase in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate or Alpinia galanga leaf extract to promote the production of hyaluronic acid in skin, an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin, and a dermatologically acceptable vehicle.

Abstract: A polymeric composition is disclosed for use in personal care products. The composition is, at room temperature, a solid solution of a long-chain alcohol having ten to fifty carbon atoms and a polyalkyl[meth]acrylate polymer having some alkyl side chains pendant the ester group having ten to thirty carbon atoms and other alkyl side chains pendant the ester group having one to eight carbon atoms. The polymer can be formed by a transesterification reaction of a polyalkyl[meth]acrylate and the long chain alcohol in the presence of a catalyst.

Abstract: Described are hair fixative compositions comprising an aqueous dispersion comprising an ethylene acrylic acid co-polymer, and optionally a metallocene catalyzed polyolefin.

Abstract: Disclosed is a method for producing resin particles, which can impart a desired function to the surface of resin particles efficiently and simply. Also disclosed are resin particles produced by the method. The method produces resin particles by melting and mixing an acidic-group-containing thermoplastic resin or elastomer with filler particles and a water-soluble material to give a resin composition containing resin fine particles formed by the thermoplastic resin and the filler particles and dispersed in a matrix including the water-soluble material; and removing the matrix component from the resin composition, to give the resin particles. The resulting resin particles each include a core particle including the acidic-group-containing thermoplastic resin or elastomer, and the filler particles immobilized on the outside of the core particle. The acidic group is preferably carboxyl group or carboxylic anhydride group.

Abstract: Formulations with antibacterial and biofilm removing actions in which the formulations have at least one plant oil from a plant from the genus Protium, Guatteria, Cyperus in a suitable vehicle.

Abstract: The present invention relates to a method of producing and loading silk particles, preferably spider silk particles, with a compound. In particular, the present invention provides a novel two step method for loading silk particles, preferably spider silk particles, with small and water-soluble compounds. Also disclosed are silk particles, preferably spider silk particles, loaded with at least one compound which are eminently suited as carriers for controlled and sustained delivery applications. Furthermore, the invention relates to pharmaceutical or cosmetic compositions comprising said silk particles, preferably spider silk particles, and a pharmaceutically active compound or cosmetic compound for controlled and sustained release. The present invention is also directed to silk particles, preferably spider silk particles, loaded with a compound obtainable by the method according to the invention.

Abstract: Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

Abstract: The present invention is directed to ophthalmic devices that are loaded with therapeutic agent. The devices provide prolonged release of the therapeutic agent to the eye. The ophthalmic devices are typically formed of an ophthalmic material that is particularly desirable for the loading of therapeutic agent and/or the therapeutic agent is typically particularly desirable for loading to the ophthalmic material.

Abstract: Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions.

Abstract: Methods for treating and preventing ocular conditions by administering an compound to the vitreous chamber of a patient at risk of, or suffering from, the ocular condition.

Abstract: The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.

Abstract: Disclosed in certain embodiments is a solid oral dosage form comprising: (a) an inert tamper resistant core; and (b) a coating surrounding the core, the coating comprising an active agent.

Abstract: The present invention includes pH dependent, dry film coating compositions containing calcium silicate for use on orally-ingestible substrates such as tablets and the like. The film coating compositions can be applied as an aqueous suspension either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is either an enteric or reverse-enteric polymer. Methods of preparing the dry film coatings, methods of preparing corresponding aqueous suspensions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.

Abstract: A capsule for suppressing appetite, comprising: a) a shell which dissolves in the stomach; and b) a plurality of elements inside the shell, which elements expand inside the stomach, after the shell dissolves, to form a connected mass with an envelope volume greater than the total volume of the elements, and at least 3 times the volume of the capsule.

Abstract: Dosage forms having a core having a surface having means for controlling release(s) on an active agent(s); methods of manufacturing, tools used in manufacturing; and uses of the dosage forms are described.

Abstract: An enteric-coated bead dosage form of cysteamine, and related methods of manufacture and use, are disclosed.

Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an amine-functionalized methacrylate copolymer.

Abstract: A method for preparing an aqueous suspension of nanocapsules comprising an oily core surrounded by a polymeric shell, comprises mixing first and second phases, wherein the first oily phase comprises a hydrophobic polymer, an oil or a mixture of oils, at least one active ingredient, and a surfactant TA1. The oily phase is brought to a temperature T1 higher than the melting point of the hydrophobic polymer, the hydrophobic polymer being miscible, at this temperature T1, with the mixture of the surfactant TA1 and the oil or mixture of oils, and the active ingredient being miscible, soluble or solubilized in the mixture of the surfactant TA1 and the oil or mixture of oils. The second polar phase comprises a hydrophilic polymer in the form of a hydrogel in an aqueous solution containing a surfactant TA2, to form the nanocapsules in an aqueous suspension.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: A fat-reducing agent includes a carotenoid-containing composition as an active ingredient, the carotenoid-containing composition including: a carotenoid component including at least one crystalline carotenoid, wherein at least 90% by mass of the crystalline carotenoid is in the non-crystalline state; and a (poly)glycerin fatty acid ester containing from 1 to 6 glycerin units and from 1 to 6 fatty acid units, and having at least one hydroxyl group in the glycerin units.

Abstract: Provided are a method for searching for a malodor inhibitor by using the response of an olfactory receptor as an indicator; a method for inhibiting malodor based on the antagonism of olfactory receptors; and a malodor inhibitor. Disclosed are a method for searching for a malodor inhibitor, the method including: adding a test substance and a malodor-causing substance to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1, measuring the response of the olfactory receptor to the malodor-causing substance, identifying the test substance that suppresses the response of the olfactory receptor on the basis of the measured response, and selecting the identified test substance as a malodor inhibitor; an antagonist to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1; a method for inhibiting malodor using the antagonist.

Abstract: Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof.

Abstract: A facile method to synthesize stable calcium carbonate microstructures is demonstrated which allows in situ encapsulation of sensitive molecules like drugs. The methodology involves a macromolecular assembly of anionic polypeptide with cationic peptide oligomer to concurrently template and hold to stabilize the mineralized structure. The heterogeneously distributed mixture of anionic and cationic residues in the macromolecular assembly, similar to that is found in natural systems assists in recognizing and coassembling Ca2+ and CO32? ionic clusters, especially for formation of a disordered precursor phase such as amorphous calcium carbonate (ACC) and further crystallization to form a metastable vaterite phase. The assembly also facilitates encapsulation of a guest molecule such as tetracycline at ambient conditions without affecting the mineralization process.

Abstract: A topical composition containing an adenosine monophosphate protein kinase (AMPK) activator and methods of administering the AMPK activator for treating acute pain or preventing the development of chronic pain in a subject. The AMPK activator is resveratrol. A second AMPK activator may also be used. The second AMPK activator is metformin. The topical composition may be administered as a gel, ointment, cream, lotion, suspension, liquid, or transdermal patch.

Abstract: Peptidomimetics that inhibit the interaction between MLL1 and WDR5 are disclosed. Methods of inhibiting MLL1 activity and methods of treating cancers also are disclosed.

Abstract: Compounds, pharmaceutical compositions and methods for treating viral and bacterial infections, by administering certain thiourea compounds, specifically acylthiourea, carboximidoylthiourea and S-alkyl isothiourea derivatives and analogs, in therapeutically effective amounts are disclosed.

Abstract: A method for obtaining improved bone quality in a vertebrate, including mammal and bird, the method comprising administering to a vertebrate, including mammal and bird, in a sufficient amount and/or at a sufficient rate to enable a desired effect, glutamate, glutamate derivatives or metabolites, glutamate analogues or mixtures thereof. Also contemplated is a method for modulating bone quality in a vertebrate, including mammal and bird, comprising administering to the vertebrate, including mammal and bird, in the need thereof, glutamate, glutamate derivatives or metabolites, glutamate analogues or mixtures thereof, for modulating the bone quality as well as a compositions for use in treatment.

Abstract: Pulmonary arterial hypertension (PAH) can be prevented in persons susceptible to the diseases and PAH patients can be treated by administering an effective dose of a leukotriene inhibitor. Suitable inhibitors include leukotriene A4 hydrolase (LTA4H) inhibitors, leukotriene B4 receptor (BLT1/BLT2) antagonists, 5-lipoxygenase (5-LO) inhibitors, and 5-lipoxygenase activating protein (FLAP) inhibitors.

Abstract: The present invention relates to the field of nutrition; in particular to the prevention and/or treatment of malnutrition. One embodiment of the present invention relates to a nutritional composition enriched in cysteine for use in the treatment and/or prevention of malnutrition and disorders related thereto. Such a composition may in particular, but not exclusively, be useful for the elderly population.

Abstract: A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic retinal derivative repeatedly over a duration of at least about 3 months. Effective synthetic retinal derivatives include 9-cis-retinyl esters, 11-cis-retinyl esters, derivatives and congeners thereof, and combinations thereof. Suitable ester substituents include carboxylates of C1-C10 monocarboxylic acids and C2-C22 polycarboxylic acids.