Patents Issued in October 6, 2016
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Publication number: 20160289760Abstract: The repertoire of the variable region of T cell receptors (TCR) or B cell receptors (BCR) is quantitatively analyzed using non-biased gene sequence analysis. The present invention provides the following: a method for quantitatively analyzing the repertoire of the variable region of the T cell receptors (TCR) or B cell receptors (BCR) of a subject by using a database, wherein the method includes (1) a step for providing a nucleic acid sample containing the nucleic acid sequence of T cell receptors (TCR) or B cell receptors (BCR) amplified in a non-biased manner from the subject; (2) a step for determining the nucleic acid sequence contained in the nucleic acid sample; and (3) a step for calculating the frequency of appearance of each gene or combination thereof on the basis of the determined nucleic acid sequence and deriving the TCR or BCR repertoire of the subject.Type: ApplicationFiled: November 20, 2014Publication date: October 6, 2016Inventors: Ryuji Suzuki, Tadasu Shini
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Publication number: 20160289761Abstract: There is provided a single stranded oligonucleotide having a 5? end and a 3? end, said oligonucleotide comprising a first and second section, the first section being positioned 5? of the second section; and wherein (i) the first section is labelled with at least two detectable labels and is capable of hybridising to a target polynucleotide; and (ii) the second section is not capable of hybridising to a target polynucleotide; said second section comprising a stem-loop structure comprising a first portion, a second portion and a third portion and wherein the second portion is located between the first and third portions, and the first and third portions are complementary to each other. There is also provided a method of detecting the presence of a target polynucleotide and/or sequence variations within a target polynucleotide using such an oligonucleotide.Type: ApplicationFiled: August 27, 2014Publication date: October 6, 2016Inventors: David French, Paul Debenham
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Publication number: 20160289762Abstract: The invention generally relates to methods for assessing a neurological disorder by characterizing circulating nucleic acids in a blood sample. According to certain embodiments, methods for assessing a neurological disorder include obtaining RNA present in a blood sample of a patient suspected of having a neurological disorder, determining a level of RNA present in the sample that is specific to brain tissue, comparing the sample level of RNA to a reference level of RNA specific to brain tissue, determining whether a difference exists between the sample level and the reference level, and indicating a neurological disorder if a difference is determined.Type: ApplicationFiled: November 6, 2014Publication date: October 6, 2016Inventors: Lian Chye Winston KOH, Stephen R. QUAKE, Hei-Mun Christina FAN, Wenying PAN
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Publication number: 20160289763Abstract: The subject invention pertains to methods of identifying miRNAs that are differentially expressed in a lymphatic vessel cell under a proinflammatory stimulus. The invention also pertains to profiles of miRNAs that are differentially expressed in a lymphatic vessel cell under a proinflammatory stimulus and their use as biomarkers for diagnosis of inflammation mediated diseases. The current invention also provides therapeutic agents for the treatment of inflammation mediated lymphatic diseases wherein the therapeutic agents are capable of modulating the activity of the miRNAs differentially expressed in a lymphatic vessel cell under a proinflammatory stimulus.Type: ApplicationFiled: November 12, 2014Publication date: October 6, 2016Inventors: MARIAPPAN MUTHUCHAMY, SANJUKTA CHAKRABORTY
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Publication number: 20160289764Abstract: Kits for detecting Kawasaki disease, containing an agent for sequencing or measuring the expression level of one or more of the following: miR-941, miR-182-5p and miR-183-5p are provided. Methods for detecting Kawasaki disease in a subject, comprising the identifying of one or more of the following in the subject: miR-941, miR-182-5p and miR-183-5p, are also provided.Type: ApplicationFiled: February 25, 2016Publication date: October 6, 2016Inventors: Ho-Chang KUO, Sung-Chou LI, Wen-Ching CHAN
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Publication number: 20160289765Abstract: This invention provides gene expression profiles useful for diagnosing lacunar stroke and for distinguishing lacunar stroke from non-lacunar stroke.Type: ApplicationFiled: April 5, 2016Publication date: October 6, 2016Applicant: The Regents of the University of CaliforniaInventors: Frank SHARP, Glen C. JICKLING
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Publication number: 20160289766Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.Type: ApplicationFiled: February 3, 2016Publication date: October 6, 2016Inventors: Kit LAU, Alice WANG
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Publication number: 20160289767Abstract: This invention is directed to a method of diagnosing bladder cancer in dogs.Type: ApplicationFiled: November 14, 2014Publication date: October 6, 2016Inventor: Matthew Breen
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Publication number: 20160289768Abstract: Particular aspects confirm the existence of a CpG island methylator phenotype (CIMP) in colorectal cancer, and provide novel validated DNA methylation markers associated with CIMP. Additional aspects provide novel methods and compositions for: determining CIMP status in colorectal cancers, determining the relationship between CIMP status and other molecular features of the cancers (e.g., BRAF mutation, KRAS mutation, and MSI status); determining the relationship between CIMP status and other variables (e.g., age, sex, tumor location, family history, race, country of origin, tumor characteristics (including, tumor type, tumor grade, invasive margin characteristics, lymphocyte infiltration characteristics, direct spread, lymph node spread, venous spread, and type of residual adjacent polyp, if present)); and determining, between subgroups defined by CIMP status and BRAF mutations, effects of selected risk factors (e.g.Type: ApplicationFiled: March 9, 2016Publication date: October 6, 2016Inventors: Peter W. Laird, Kimberly D. Siegmund, Mihaela Campan, Daniel J. Weisenberger, Tiffany I. Long
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Publication number: 20160289769Abstract: Methods for characterizing a cell employ a library of nanoparticle conjugates of one or more types, each type of nanoparticle conjugate comprising a nanoparticle, targeting entities of one or more types, and tags of one or more types, to determine the genotype and phenotype of a cell as well as other characteristics. The tags can include oligonucleotide barcodes.Type: ApplicationFiled: March 30, 2016Publication date: October 6, 2016Inventors: Jerrod Joseph SCHWARTZ, Alberto Clemente VITARI
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Publication number: 20160289770Abstract: The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Human Double Minute inhibitors (MDM2i), methods of determining the sensitivity of a cell to an MDM2i by measuring biomarkers and methods of screening for candidate MDM2i.Type: ApplicationFiled: May 18, 2016Publication date: October 6, 2016Applicant: Novartis AGInventors: Swann Gaulis, Sebastien Jeay
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Publication number: 20160289771Abstract: The present invention relates in general to the field of colorectal cancer detection, and more particularly, to plasma microRNAs for the detection of early colorectal cancer.Type: ApplicationFiled: June 14, 2016Publication date: October 6, 2016Inventors: Meritxell Gironella Cos, Juan José Lozano Salvatella, Antoni Castells Garangou, María Dolores Giraldez Jiménez
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Publication number: 20160289772Abstract: The present invention relates to methods for predicting, diagnosing and monitoring cancer. The methods comprise obtaining biological samples, extracting mitochondrial DNA (mtDNA) from the samples, quantifying mitochondrial DNA mutation in the sample and comparing the level of mtDNA mutation with a reference value. The methods of the invention may also be effective in screening for new therapeutic agents and treatment regimes, and may also be useful for monitoring the response of a subject to a preventative or therapeutic treatment.Type: ApplicationFiled: June 21, 2016Publication date: October 6, 2016Inventors: Ryan Parr, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Katrina Maki, Gabriel Dakubo, Brian Reguly, Andrew Harbottle, Jude Alexander
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Publication number: 20160289773Abstract: The present disclosure concerns the determination of the resistance or the susceptibility of a nematode to an imidazothiazole anti-helmintic based on the assessment of the presence of an indel in the Hco-acr-8 gene (or the Hco-acr-8 gene ortholog). The present disclosure also provides tools and commercial packages for making such assessment.Type: ApplicationFiled: July 11, 2014Publication date: October 6, 2016Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MC GILL UNIVERSITYInventors: Roger Prichard, Virginie Barrere, Robin Beech, Cedric Neveu
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Publication number: 20160289774Abstract: K13-propeller polymorphism is a useful molecular marker for tracking the emergence and spread of ART-resistant P. falciparum. The invention encompasses methods, compositions, and kits for detecting and genotyping Plasmodium, for example, Plasmodium falciparum. The methods, compositions, and kits can be used to detect the presence or absence of a mutated K-13 propeller nucleic acid or protein in the sample.Type: ApplicationFiled: November 14, 2014Publication date: October 6, 2016Inventors: Frederic ARIEY, Odile PUIJALON, Didier MENARD, Francoise BENOIT-VICAL, Johann BEGHAIN, Benoit WITKOWSKI, Jean-Christophe BARALE, Christiane BOUCHIER, Nimol KHIM
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Publication number: 20160289775Abstract: A system, device, and method for rapid detection of analytes that includes a living, engineered biosensor cell that is typically a component of the mammalian immune system; a reporter protein that is engineered into and expressed by the living, engineered biosensor cell, wherein the reporter protein emits a detectable signal in response to certain predetermined changes in the cytosol of the living, engineered cell; a signal transduction pathway expressed by the living, engineered biosensor cell, wherein the signal transduction pathway controls a biological process within the cytosol of the living, engineered biosensor cell, and wherein the biochemical process, when it occurs, causes the reporter protein to emit a detectable signal; at least one type of detector molecule that is adapted to bind to a specific analyte; at least one analyte that binds to the detector molecule that is specific to that analyte; a plurality of non-antibody signal transducing elements that are either expressed by the living, engineerType: ApplicationFiled: March 31, 2016Publication date: October 6, 2016Applicant: FUNDAMENTAL SOLUTIONS CORPORATIONInventors: Thomas J. ZUPANCIC, Lingchun ZENG, Srikanth VEDAMOORTHY, Joel S. LWANDE, Joesph D. KITTLE
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Publication number: 20160289776Abstract: The present invention relates to a cell which is genetically modified with respect to its wild type and which comprises a gene sequence coding for an autofluorescent protein, wherein the expression of the autofluorescent protein depends on the intracellular concentration of a particular metabolite. The present invention also relates to a method for the identification of a cell having an increased intracellular concentration of a particular metabolite, a method for the production of a cell which is genetically modified with respect to its wild type with optimized production of a particular metabolite, a cell obtained by this method, a method for the production of metabolites and a method for the preparation of a mixture.Type: ApplicationFiled: May 5, 2016Publication date: October 6, 2016Inventors: Lothar Eggeling, Michael Bott, Stephan Binder, Julia Frunzke, Nurije Mustafi
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Publication number: 20160289777Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: June 15, 2016Publication date: October 6, 2016Applicant: The Government of the U.S.A. as represented by the Secretary of the Dept. of Health and Human ServicInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Publication number: 20160289778Abstract: The present invention relates to methods for determining genotypes of pathogens present in a sample, e.g. a clinical sample, using next generation sequencing, in particular ion semiconductor sequencing. The present invention also relates to apparatus comprising computer units for carrying out the genotyping methods disclosed herein as well as to software products suitable for the execution of the methods disclosed herein.Type: ApplicationFiled: October 31, 2014Publication date: October 6, 2016Inventors: Pramila Nuwantha ARIYARATNE, Charlie Wah Heng LEE
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Publication number: 20160289779Abstract: The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.Type: ApplicationFiled: March 30, 2015Publication date: October 6, 2016Applicant: Enzo Biochem, Inc.Inventors: ZAIGUO LI, PRAVEEN PANDE, NATARAJAN RAJU
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Publication number: 20160289780Abstract: The present disclosure is generally related a method for the liquefaction of high-solids biomass substrates. Particularly, biomass can be added to a reactor until a pressure drop, measured inline, reaches the maximum system limitations. A commercial enzyme mixture (specific for the particular type of biomass to be processed) may then be added to the biomass, forming a slurry. The pressure may be continuously monitored and when the pressure drop reaches a steady state (which can be determined by little or no change in pressure drop for several minutes), more biomass may then be added until the high pressure limit of the pump system is reached again. The method can be repeated until the desired quantity of biomass is processed.Type: ApplicationFiled: April 5, 2016Publication date: October 6, 2016Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ASPECT AI LTD.Inventors: Maria Cardona, Robert Louis Powell, III, Michael John McCarthy, Tina Jeoh Zicari, Emilio Javier Tozzi
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Publication number: 20160289781Abstract: A strain of marine oil degrading bacteria, compounds obtained by fermentation and their uses are published. The name is Alcanivorax dieselolei T6-6, with preservation Number: CGMCC NO: 9033. It belongs to ?-proteobacteria, oceanospirillales, alkane degrading bacteria branch, alcanivorax category and diesel alcanivorax species. The said bacteria can be used to degrade and remove petroleum hydrocarbon, control environmental pollution, produce surfactants, reduce surface tension of water, and for other purposes; a compound can be isolated from secondary metabolites after fermentation, one of which is dieselolei T6-6, 2-amino-6-(N-2-carbonyl-4-tridecyl-cyclobutane) hexanoic acid, and it is a kind of lysine ester. The compound has emulsifying activity on different organics, antibacterial effects against Gram-positive bacteria and fungus, and a better cytotoxic activity.Type: ApplicationFiled: February 6, 2015Publication date: October 6, 2016Applicants: THIRD INSTITUTE OF OCEANOGRAPHY,STATE OCEANIC ADMI NISTRATION, CHINA OCEAN MINERAL RESOURCES RESEARCH AND DEVELOP MENT ASSOCIATIONInventors: Zongze SHAO, Xiaoman SHI, Wanpeng WANG
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Publication number: 20160289782Abstract: The present disclosure relates to bioengineering approaches for producing biofuel and, in particular, to the use of a C1 metabolizing microorganism reactor system for converting C1 substrates, such as methane or methanol, into biomass and subsequently into biofuels, bioplastics, or the like.Type: ApplicationFiled: June 20, 2016Publication date: October 6, 2016Inventors: Joshua A. Silverman, Sol M. Resnick, Michael Mendez, Renee M. Saville, Sungwon Lee, Luan Nguyen
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Publication number: 20160289783Abstract: The invention relates to a method for treating desulfurization slag, in which desulfurization slag from pig iron desulfurization is conveyed to a suitable unit in which the desulfurization slag is melted at a temperature of at least 1,400° C., said unit assuring a thorough mixing, and the treatment takes place in the unit under slightly oxidizing conditions, with the SO2 generated being collected from the roasting gas and supplied for further utilization.Type: ApplicationFiled: November 27, 2014Publication date: October 6, 2016Inventors: Karl Pilz, Bertram Fritz, Jürgen Antrekowitsch, Gerald Schneeberger
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Publication number: 20160289784Abstract: A high-strength steel sheet and a method for manufacturing a high-strength steel sheet having excellent phosphatability and excellent corrosion resistance after electrodeposition coating has been performed, even in the case where the contents of Si and Mn are high. The method may comprise annealing a steal sheet by using a continuous annealing method, performing a heating process, controlling the maximum end-point temperature of a steel sheet in the annealing furnace, controlling the traveling time of the steel sheet, and controlling the dew point of the atmosphere.Type: ApplicationFiled: November 13, 2014Publication date: October 6, 2016Applicant: JFE STEEL CORPORATIONInventors: Yusuke FUSHIWAKI, Yoshiyasu KAWASAKI
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Publication number: 20160289785Abstract: A martensitic stainless steel containing, by mass %, C: 0.20% to 0.40%, N: 0.1% or less, Mo: 3% or less, and Cr: 12.0% to 16.0%, such that 0.3%?C+N?0.4% and a PI value (=Cr+3.3Mo+16N) is 18 or more, with the remainder being substantially Fe and unavoidable impurities is quenched from a temperature of 1,030° C. to 1,140° C. and subjected to a subzero treatment and tempering so as to obtain a prior austenite crystal grain size of a surface layer of 30 ?m to 100 ?m and a surface hardness of 58 HRc to 62 HRc.Type: ApplicationFiled: November 13, 2014Publication date: October 6, 2016Applicant: NSK LTD.Inventors: Chikara MATSUZAWA, Takafumi YASUHARA, Hiroshi NISHIZAWA, Norihiro AOKI, Koji TAKANO, Masaru KUGE
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Publication number: 20160289786Abstract: A ferrite-martensite dual-phase stainless steel has satisfactory corrosion resistance and workability for a material for the body of a freight car and excellent low-temperature toughness. The ferrite-martensite dual-phase stainless steel has a specified chemical composition, in which inequalities (I) and (II) below are satisfied, and a steel microstructure including a dual phase of a ferrite phase and a martensite phase, in which the content of the martensite phase is 5% or more and 95% or less in terms of vol. %: 10.5?Cr+1.5×Si?13.5??(I) 1.5?30×(C+N)+Ni+0.5×Mn?6.0??(II), where Cr and Si in inequality (I) above and C, N, Ni, and Mn in inequality (II) above respectively represent the contents (mass %) of the corresponding chemical elements.Type: ApplicationFiled: October 27, 2014Publication date: October 6, 2016Inventors: Tomohiro Ishii, Hiroki Ota, Chikara Kami, Saiichi Murata, Mitsuyuki Fujisawa, Genichi Ishibashi
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Publication number: 20160289787Abstract: A high-carbon steel sheet has a chemical composition represented by, in mass %, C: 0.60% to 0.90%, Mn: 0.30% to 1.50%, and Cr: 0.20% to 1.00%, and others, and has a structure represented by a concentration of Mn contained in cementite: 2% or more and 8% or less, a concentration of Cr contained in cementite: 2% or more and 8% or less, an average grain diameter of ferrite: 10 ?m or more and 50 ?m or less, an average particle diameter of cementite: 0.3 ?m or more and 1.5 ?m or less, and a spheroidized ratio of cementite: 85% or more.Type: ApplicationFiled: November 21, 2014Publication date: October 6, 2016Applicant: NIPPON STEEL & SUMITOMO METAL CORPORATIONInventors: Kengo TAKEDA, Toshimasa TOMOKIYO, Yasushi TSUKANO, Takashi ARAMAKI
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Publication number: 20160289788Abstract: A hot-rolled steel sheet has a chemical composition containing, by mass %, C: 0.030% or more and 0.120% or less, Si: 0.05% or more and 0.50% or less, Mn: 1.00% or more and 2.20% or less, P: 0.025% or less, S: 0.0050% or less, N: 0.0060% or less, Al: 0.005% or more and 0.100% or less, Nb: 0.020% or more and 0.100% or less, Mo: 0.05% or more and 0.50% or less, Ti: 0.001% or more and 0.100% or less, Cr: 0.05% or more and 0.50% or less, Ca: 0.0005% or more and 0.0050% or less, and the balance being Fe and inevitable impurities, and has a microstructure including bainitic ferrite as a main phase and martensite and retained austenite as second phases, wherein a volume fraction of the main phase is 90% or more, an average grain diameter of the main phase is 10 ?m or less, a volume fraction of the martensite is 0.5% or more and 9.5% or less, and a volume fraction of the retained austenite is 0.5% or more and 9.Type: ApplicationFiled: November 20, 2014Publication date: October 6, 2016Inventors: Tomoaki Shibata, Sota Goto
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Publication number: 20160289789Abstract: Embodiments of the present invention provide an electromagnetic sensor (400) for detecting a microstructure of a metal target, comprising: a magnetic device (410, 420) for providing an excitation magnetic field; a magnetometer (430) for detecting a resultant magnetic field induced in a metal target; and a calibration circuit (450, 551, 552, 553, 554) for generating a calibration magnetic field for calibrating the electromagnetic sensor, wherein the calibration reference magnetic field is generated by an electrical current induced in the calibration circuit by the excitation magnetic field.Type: ApplicationFiled: June 9, 2016Publication date: October 6, 2016Inventors: Anthony Joseph Peyton, Wuliang Yin, Stephen John Dickinson
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Publication number: 20160289790Abstract: Processes, systems, and methods for selectively regenerating an ion exchange resin generally comprises washing the ion exchange resin with an elution agent that encourages only selected contaminants, and especially selected radioactive isotopes, to disengage or decouple from the resin and enter solution in the elution agent, which thereafter is identified as the elution agent solution. The elution agent solution is then passed through a column of isotope-specific media (ISM). When the selected radioactive isotopes within the elution agent solution come into contact with the constituent media isotopes of the ISM, the selected radioactive isotopes are retained on the reactive surface areas of the ISM or within the interstitial spaces of the porous structures of the constituent media isotopes of the ISM. In some embodiments, the constituent media isotopes of the ISM are embedded, impregnated, or coated with the specific radioactive isotope that the particular ISM are adapted to separate.Type: ApplicationFiled: May 11, 2016Publication date: October 6, 2016Applicant: Kurion, Inc.Inventor: Mark S. DENTON
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Publication number: 20160289791Abstract: Disclosed herein, is a process for recovering- valuable metals and/or their oxides from red mud bauxite residues or similar. The process comprises: calcining a red mud residue having a pH of less than about 10 to provide a calcinated red mud residue; acid leaching the calcinated red mud residue to provide a silica rich solid component and an acid leachate; separating the silica rich solid component and the acid leachate; precipitating an iron rich solid component from the acid leachate; and separating the precipitated iron rich solid component from the acid leachate to provide an aluminium rich liquor.Type: ApplicationFiled: October 21, 2014Publication date: October 6, 2016Applicant: PELOTON RESOURCES PTY LTDInventors: Richard MORRIS, Matthew Charles, Leighton TODD, David Adam LENYSZYN, Terence John O'CONNOR
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Publication number: 20160289792Abstract: A process is provided for preparing a spent noble metal fixed-bed catalyst for precious metals recovery, comprising: a) adding the catalyst to a caustic solution to wash the spent catalyst and to make a wash slurry having an alkaline pH, wherein the spent catalyst has been in contact with chloroaluminate ionic liquid catalyst, and wherein the spent catalyst comprises from 5 to 35 wt % chloride; and b) filtering the wash slurry and collecting: i) a filter cake having from at least 70 wt % of the chloride in the spent catalyst removed and having the noble metals retained, and ii) a wash filtrate. Also provided is a filter cake comprising a washed consolidated cake having 40 to 75 wt % solids, a cake moisture content from 25 to less than 60 wt %, 0.1 to 1.5 wt % total noble metals, and a residual chloride content of from zero to less than 4 wt %.Type: ApplicationFiled: June 17, 2016Publication date: October 6, 2016Inventors: Rahul Shankar Bhaduri, Hye Kyung Cho Timken, Phillip Ian Cuspard
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Publication number: 20160289793Abstract: A method to be used in conjunction with a single-stage or multi-stage process for leaching ash originating from the recovery boiler of a pulp mill, particularly when the ash contains a significant amount of carbonate, wherein calcium compounds, such as calcium oxide (CaO) or calcium hydroxide (Ca(OH)2), are employed as additives in one or more leaching stages, a liquid fraction formed in the leaching process is utilized outside the main chemical recovery cycle, such as a substitute for purchased sodium hydroxide in the bleaching line of the pulp mill, and a solids fraction may be mixed with a black-liquor stream of the mill or subjected to further processing to separate calcium compounds for recycle.Type: ApplicationFiled: November 15, 2013Publication date: October 6, 2016Inventor: Paterson McKEOUGH
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Publication number: 20160289794Abstract: A cation adsorbent of an embodiment includes tungsten oxide particles having a BET specific surface area in a range of 0.82 m2/g or more and 820 m2/g or less. The cation adsorbent is added to a solution to be treated containing cations being recovery objects, and the cation adsorbent adsorbing the cations is precipitated. The generated precipitate is separated from the solution to recover the cations.Type: ApplicationFiled: June 9, 2016Publication date: October 6, 2016Applicants: Kabushiki Kaisha Toshiba, Toshiba Materials Co., Ltd.Inventors: Akira SATO, Daisuke FUKUSHI, Takao KUSAKA, Kayo NAKANO, Yukiko INUI, Akito SASAKI
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Publication number: 20160289795Abstract: A method is provided for extracting scandium values from a scandium bearing laterite ore. The method includes providing a portion of a scandium bearing laterite ore having an average particle size of no more than 200 mesh, leaching the ore to produce a leachate, and recovering scandium values from the leachate.Type: ApplicationFiled: February 10, 2016Publication date: October 6, 2016Applicant: Scandium International Mining CorporationInventor: Willem P.C. Duyvesteyn
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Publication number: 20160289796Abstract: The invention relates to the use of an organic-inorganic hybrid material, comprising an inorganic solid support on which are grafted organic molecules having the general formula (I) below: in which: x, y and z=0 or 1, with at least one of x, y and z different from 0; m=1 to 6; v and w=0 or 1, with v=1 when w=0, and v=0 when w=1; if x=0, R1?H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if x=1, R1=a group bound to the inorganic solid support by at least one covalent bond; if y=0, R2?H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if y=1, R2=a group bound to the inorganic solid support by at least one covalent bond; if z=0, R3?H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if z=1, R3=a group bound to the inorganic solid support by at least one covalent bond; R4 and R5?H, a saturated or unsaturated, linear or branched, C2 to C8 hydrocarbon group, or a monocyclic aromatic groupType: ApplicationFiled: November 6, 2014Publication date: October 6, 2016Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Agnès GRANDJEAN, Frédéric CUER
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Publication number: 20160289797Abstract: A copper-zinc alloy having the following composition (in % by weight): from 67.0 to 69.0% of Cu, from 0.4 to 0.6% of Si, from 1.2 to 1.6% of Mn, from 0.03 to 0.06% of P, optionally up to a maximum of 0.5% of Al, optionally up to a maximum of 0.15% of Ni, optionally up to a maximum of 0.1% of Fe, optionally up to a maximum of 0.1% of Pb, optionally up to a maximum of 0.08% of Sn, optionally up to a maximum of 0.1% of S, balance Zn and unavoidable impurities. The alloy has a microstructure which consists of an ?-phase matrix in which inclusions of manganese silicides having a globular shape are present in a proportion of at least 2% by volume and not more than 5% by volume.Type: ApplicationFiled: March 4, 2016Publication date: October 6, 2016Inventors: Hans-Achim KUHN, Gerhard THUMM, Maher ABABNEH, Volker VOGGESER, Jeremy BELL
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Publication number: 20160289798Abstract: A nickel-chromium-molybdenum-copper alloy resistant to 70% sulfuric acid at 93° C. and 50% sodium hydroxide at 121° C. for acid and alkali neutralization in the field of waste management; the alloy contains, in weight percent, 27 to 33 chromium, 4.9 to 7.8 molybdenum, greater than 3.1 but no more than 6.0 copper, up to 3.0 iron, 0.3 to 1.0 manganese, 0.1 to 0.5 aluminum, 0.1 to 0.8 silicon, 0.01 to 0.11 carbon, up to 0.13 nitrogen, up to 0.05 magnesium, up to 0.05 rare earth elements, with a balance of nickel and impurities.Type: ApplicationFiled: June 9, 2016Publication date: October 6, 2016Inventors: Vinay P. Deodeshmukh, Nacera Sabrina Meck, Paul Crook
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Publication number: 20160289799Abstract: A nickel-chromium-molybdenum-copper alloy resistant to 70% sulfuric acid at 93° C. and 50% sodium hydroxide at 121° C. for acid and alkali neutralization in the field of waste management; the alloy contains, in weight percent, 27 to 33 chromium, 4.9 to 7.8 molybdenum, 3.1 to 6.0 wt. % copper (when chromium is between 30 and 33 wt. %) or 4.7 to 6.0 wt. % copper (when chromium is between 27 and 29.9 wt. %), up to 3.0 iron, 0.3 to 1.0 manganese, 0.1 to 0.5 aluminum, 0.1 to 0.8 silicon, 0.01 to 0.11 carbon, up to 0.13 nitrogen, up to 0.05 magnesium, up to 0.05 rare earth elements, with a balance of nickel and impurities. Titanium or another MC carbide former can be added to enhance thermal stability of the alloy.Type: ApplicationFiled: June 9, 2016Publication date: October 6, 2016Inventors: Paul Crook, Vinay P. Deodeshmukh
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Publication number: 20160289800Abstract: Alloys, processes for preparing the alloys, and manufactured articles including the alloys are described. The alloys include, by weight, about 10% to about 20% chromium, about 4% to about 7% titanium, about 1% to about 3% vanadium, 0% to about 10% iron, less than about 7% nickel, 0% to about 10% tungsten, less than about 3% molybdenum, and the balance of weight percent including cobalt and incidental elements and impurities.Type: ApplicationFiled: August 28, 2013Publication date: October 6, 2016Inventors: James A. Wright, Jason T. Sebastian, David R. Snyder, Jiadong Gong, Jeremy Hoishun Li
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Publication number: 20160289801Abstract: An object of the present invention is to provide an aluminium grain material having significantly high purity, and a method for producing the same. Disclosed is an aluminium grain material having an average mass per grain of 0.01 to 10 g, wherein the total content of twelve elements of silicon (Si), iron (Fe), copper (Cu), magnesium (Mg), titanium (Ti), vanadium (V), chromium (Cr), manganese (Mn), nickel (Ni), zinc (Zn), gallium (Ga), and zirconium (Zr) in the aluminium grain material, measured by glow discharge mass spectrometry, is 5 ppm by mass or less.Type: ApplicationFiled: April 4, 2016Publication date: October 6, 2016Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Hiroaki HOSHIKAWA, Yuki KUBO, Akira NAGATA
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Publication number: 20160289802Abstract: In a first aspect, the invention provides aluminum alloy comprising the following composition, all values in weight %: Si 0.25-1.5 Cu 0.3-1.5 Fe up to 0.5 Mn up to 0.1 all other elements including Mg being incidental and present (if at all) then in an amount less than or equal to 0.05 individually, and less than or equal to 0.15 in aggregate, the balance being aluminum. In a second aspect, the invention provides a composite aluminum sheet product comprising a core layer and at least one clad layer wherein the at least one clad layer is an aluminum alloy comprising the following composition, all values in weight %: Si 0.25-1.5 Cu 0.3-1.5 Fe up to 0.5 Mn up to 0.1 all other elements including Mg being incidental and present (if at all) then in an amount less than or equal to 0.05 individually, and less than or equal to 0.15 in aggregate, the balance being aluminum.Type: ApplicationFiled: April 28, 2016Publication date: October 6, 2016Applicant: NOVELIS INC.Inventors: CYRILLE BEZENCON, CORRADO BASSI, FRANK SCHELLINGER
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Publication number: 20160289803Abstract: Embodiments of alloys having high, fine-grained carbide content, and methods of manufacturing such alloys. The alloys can be determined through the use of thermodynamic, microstructural, and compositional criterial in order to create a high strength and high toughness alloy. In some embodiments, the alloys can be used as a wear resistant component.Type: ApplicationFiled: April 5, 2016Publication date: October 6, 2016Inventors: Justin Lee Cheney, Cameron Eibl
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Publication number: 20160289804Abstract: A sintered alloy having superior heat resistance and superior wear resistance and also having corrosion resistance against salt damage that may occur in cold-weather regions, and a production method therefor, are provided. The sintered alloy consists of, by mass %, 32.4 to 48.4% of Cr, 2.9 to 10.0% of Mo, 0.9 to 2.9% of Si, 0.3 to 1.8% of P, 0.7 to 3.9% of C, and the balance of Fe and inevitable impurities, and it has a density ratio of not less than 90% and includes carbides that are dispersed in a matrix of a metallic structure thereof.Type: ApplicationFiled: November 30, 2015Publication date: October 6, 2016Applicant: HITACHI CHEMICAL COMPANY, LTD.Inventors: Daisuke FUKAE, Hideaki KAWATA
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Publication number: 20160289805Abstract: A martensitic stainless steel is provided, wherein its composition is: trace amounts?C?0.030%; trace amounts?Si?0.25%; trace amounts?Mn?0.25%; trace amounts?S?0.020%; trace amounts?P?0.040%; 8%?Ni?14%; 8%?Cr?14%; 1.5%?Mo+W/2?3.0%; 1.0%?Al?2.0%; 0.5%?Ti?2.0%; 2%?Co?9%; trace amounts?N?0.030%; trace amounts?O?0.020%; the remainder being iron and impurities resulting from the steelmaking; and its martensitic transformation beginning temperature Ms is calculated by the formula Ms (° C.)=1302?28Si?50Mn?63Ni?42Cr?30Mo+20Al?12Co?25Cu+10[Ti?4(C+N)]??(1) wherein the contents of the various elements are expressed in weight percentages, is greater than or equal to 50° C., preferably greater than or equal to 75° C. A part made in this steel and its manufacturing method are also provided.Type: ApplicationFiled: November 25, 2014Publication date: October 6, 2016Applicant: AUBERT & DUVALInventor: Sylvain Pierre PUECH
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Publication number: 20160289806Abstract: To provide a Cu—Ni—Si based rolled copper alloy having excellent strength, electric conductivity and fatigue properties, disclosed is a Cu—Ni—Si based rolled copper alloy, comprising: a total amount of 3.0 to 4.5% by mass of at least one or more selected from the group consisting of Ni and Co, 0.6 to 1.0% by mass of Si, and the balance Cu and inevitable impurities, wherein a 0.2% yield strength YS in a direction transverse to rolling direction is 1040 MPa or more.Type: ApplicationFiled: March 29, 2016Publication date: October 6, 2016Inventor: Hiroshi Kuwagaki
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Publication number: 20160289807Abstract: Age-hardening nickel-chromium-iron-titanium-aluminum wrought alloy with very good wear resistance and at the same time good creep strength, good high-temperature corrosion resistance and good processability, with (in mass-%)>18 to 26% chromium, 1.5 to 3.0% titanium, 0.6 to 2.0% aluminum, 7.0 to 40% iron, 0.005 to 0.10% carbon, 0.0005 to 0.050% nitrogen, 0.0005 to 0.030% phosphorus, max. 0.010% sulfur, max. 0.020% oxygen, max. 0.70% silicon, max. 2.0% manganese, max. 0.05% magnesium, max. 0.05% calcium, max. 0.5% molybdenum, max. 0.5% tungsten, max. 0.2% niobium, max. 0.5% copper, max. 0.5% vanadium, if necessary 0 to 15% Co, if necessary 0 to 0.20% Zr, if necessary 0.0001 to 0.008% boron, wherein optionally the following elements may also be contained in the alloy: Y 0-0.20% and/or La 0-0.20% and/or Ce 0-0.20% and/or Ce mixed metal 0-0.20% and/or Hf 0-0.20% and/or Ta 0-0.Type: ApplicationFiled: January 12, 2015Publication date: October 6, 2016Applicant: VDM Metals GmbHInventor: Heike HATTENDORF
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Publication number: 20160289808Abstract: A method for processing a dispersion-hardened platinum composition is provided. A three-dimensional body of a dispersion-hardened platinum composition containing at least 70% by weight platinum and maximally 29.95% by weight other precious metals, as well as 0.05% by weight to 0.5% by weight of at least one partially-oxidized non-precious metal selected from zirconium, cerium, scandium, and yttrium is provided and cold formed, whereby the cross-sectional area of the three-dimensional body is reduced by maximally 20% during the cold forming, Subsequently a temperature treatment is performed on the cold-formed three-dimensional body, in which the cold-formed product is tempered at at least 1,100° C. for at least one hour. A method for producing a product made of a dispersion-hardened platinum composition, a dispersion-hardened platinum material obtained according to the processing method, and the use of a dispersion-hardened platinum material are also described.Type: ApplicationFiled: December 4, 2014Publication date: October 6, 2016Applicant: HERAEUS DEUTSCHLAND GMBH & CO. KGInventor: Dirk MAIER
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Publication number: 20160289809Abstract: A steel for hot forming. The steel for hot forming has the following composition in weight%: C: 0.10-0.25, Mn: 1.4-2.6, Si:<0.4, Cr:<1.0, Al:<1.5, P:<0.02, S:<0.005, N:<0.03, B:<0.0004, 0:<0.008 and optionally: Ti:<0.3, Mo:<0.5, Nb:<0.3, V:<0.5, Ca:<0.05, the remainder being iron and unavoidable impurities.Type: ApplicationFiled: September 19, 2014Publication date: October 6, 2016Inventors: David Neal HANLON, Stefanus Matheus, Cornelis VAN BOHEMEN