Patents Issued in May 2, 2017
  • Patent number: 9637538
    Abstract: A monoclonal chimeric immunoglobulin wherein the heavy chains and the light chains are human by nature in their constant parts, in particular, the heavy chain constant parts are chosen from the group formed of the heavy chain constant parts of an IgA, of an IgG or of an IgM and the light chain constant parts are chosen from the group formed of the kappa chains and the lambda chains, and the light chain and the heavy chain variable parts are chosen from the group formed of monoclonal antibodies specific to monomorphic epitopes of HLA class I antigens and monoclonal antibodies specific to monomorphic epitopes of HLA class II antigens. A process for standardization of the screening and for quantification of anti-HLA antibodies in a liquid medium is also described.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: May 2, 2017
    Assignees: UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE, INVIVOGEN
    Inventors: Antoine Blancher, Nicolas Congy, Jean-Gerard Tiraby, Daniel Drocourt
  • Patent number: 9637539
    Abstract: This invention features antibodies that specifically bind to a human Dragon family protein.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: May 2, 2017
    Assignee: The General Hospital Corporation
    Inventors: Clifford J. Woolf, Tarek A. Samad
  • Patent number: 9637540
    Abstract: Compositions and methods are disclosed herein for producing one or more immunoglobulins in an isolated B lymphocyte cell line. An isolated cell line includes an isolated B lymphocyte cell line capable of expressing at least one exogenously incorporated membrane immunoglobulin reactive to a first antigen and at least one endogenous secreted immunoglobulin reactive to a second antigen.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: May 2, 2017
    Assignee: Elwha LLC
    Inventors: Roderick A. Hyde, Wayne R. Kindsvogel
  • Patent number: 9637541
    Abstract: An anti-c-Met/anti-Ang2 bispecific antibody, a composition including the anti-c-Met/anti-Ang2 bispecific antibody, and a method of preventing and/or treating a cancer in a subject including administering the anti-c-Met/anti-Ang2 bispecific antibody to the subject.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: May 2, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Hyung-Chan Kim, Kyung Eun Kim, Yoon Sook Lee, Mi Young Cho
  • Patent number: 9637542
    Abstract: The present invention relates to CX3CR1-targeting imaging agents and their use in treatment and diagnosis of diseases. Single domain CX3CR1-targeting polypeptides linked to detection labels and their use in in vivo imaging of atherosclerotic plaques are described. The CX3CR1-targeting imaging agents are useful in the treatment and diagnosis of CX3CR1-mediated diseases including atherosclerosis.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: May 2, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Alisa K. Waterman, Nick Mark Devoogdt, Tony Lahoutte, Matthias Schneider, Sanjaya Singh, Cedric Jozef Néotère Ververken
  • Patent number: 9637543
    Abstract: Provided herein are antibodies specific for HER3. Also provided are methods of treating cancer in a subject comprising administering an effective amount of the antibodies described herein to the subject.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: May 2, 2017
    Assignees: THE UAB RESEARCH FOUNDATION, BEIJING COTIMES BIOTECH CO., LTD.
    Inventors: Tong Zhou, Donald J. Buchsbaum, Enyun Shen, Xian Chen
  • Patent number: 9637544
    Abstract: Novel mutated humanized 12G4 antibodies, and fragments thereof, directed against the anti-Müllerian hormone type II receptor.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: May 2, 2017
    Assignees: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES, UNIVERSITE MONTPELLIER I, CENTRE NATIONAL DE LUTTE CONTRE LE CANCER, I.N.S.E.R.M. (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Christian Behrens, Isabelle Navarro-Teulon
  • Patent number: 9637545
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: May 2, 2017
    Assignee: KYOWA HAKKO KIRIN CO., LTD
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Patent number: 9637546
    Abstract: The invention relates to PD-1 antibodies and PD-L1 antibodies and uses thereof.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: May 2, 2017
    Inventors: Daniel Olive, Nacer-Eddine Serriari, Jacques Nunes, Marguerite Ghiotto
  • Patent number: 9637547
    Abstract: The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: May 2, 2017
    Assignee: ImmunoGen, Inc.
    Inventors: Olga Ab, Daniel Tavares, Julianto Setiady, Sharron Ladd, Christina N. Carrigan, Lingyun Rui
  • Patent number: 9637548
    Abstract: The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of colorectal, in particular colonic, and gastric tumor tissues and colorectal, in particular colonic, and gastric tissues, and which represent targets for therapy or diagnosis of such tumor diseases in a subject.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: May 2, 2017
    Assignees: GANYMED PHARMACEUTICALS AG, JOHANNES GUTENBERG-UNIVERSITAT MAINZ
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski
  • Patent number: 9637549
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: May 2, 2017
    Assignee: Janssen Biotech, Inc.
    Inventors: William Strohl, Omid Vafa
  • Patent number: 9637550
    Abstract: Disclosed herein are monoclonal antibodies specific for factor XI (fXI) that prevent activation of fXI by factor XIIa (fXIIa). The monoclonal antibodies are universal fXI antibodies, capable of binding all mammalian species tested. The anti-fXI monoclonal antibodies prolong clotting time in mammalian plasmas. Moreover, administration of the fXI monoclonal antibodies disclosed herein results in inhibition of thrombosis without altering hemostasis in animal models of thrombosis. Thus, provided herein are monoclonal antibodies specific for fXI that block activation of fXI by fXIIa, compositions and immunoconjugates comprising such antibodies and their methods of use.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: May 2, 2017
    Assignees: Oregon Health & Science University, Vanderbilt University
    Inventors: Andras Gruber, Erik I. Tucker, David Gailani
  • Patent number: 9637551
    Abstract: The present invention provides multi-component inhibitors of nucleic acid polymerases, methods of making, and methods of using same. One component of the multi-component inhibitor is a molecule that binds to a polymerase (i.e., a polymerase-binding molecule (PBM)), but does not thereby substantially inhibit its polymerase activity. Another component is a molecule or complex of molecules that binds to a PBM (i.e., a PBM-binding molecule). The combination of the PBM and PBM-binding molecule/complex substantially inhibits polymerase activity.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: May 2, 2017
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: John D. Bishop, Jun E. Lee
  • Patent number: 9637552
    Abstract: The invention provides a method for treating a medical condition, disease, or disorder mediated by a misfolded form of superoxide dismutase (SOD) in a subject in need of treatment. The method optionally comprises administering to the subject a composition comprising a pharmaceutically acceptable vehicle and an agent selected from (1) an exogenous antibody or fragment thereof that binds selectively to the misfolded form of SOD, and/or (2) an immunogen that elicits production of an endogenous antibody that binds selectively to the misfolded form of SOD, and/or (3) a nucleic acid sequence encoding (1) or (2). In certain embodiments, the invention provides methods of treating diseases such as Alzheimer's Disease, Parkinson's Disease or amyotrophic lateral sclerosis using amyotrophic disease-specific epitopes, and compositions including these epitopes. The invention also provides antibodies that bind to monomeric or misfolded SOD1, and not on the molecular surface of native homodimeric SOD1.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: May 2, 2017
    Assignee: ProMIS Neurosciences Inc.
    Inventors: Neil R. Cashman, Avijit Chakrabartty, Rishi Rakhit, Joachim Bernhard Ostermann
  • Patent number: 9637553
    Abstract: The present invention relates to antibodies anti-sPLA2-IIA and uses thereof.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: May 2, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE NICE SOPHIA ANTIPOLIS
    Inventors: Gerard Lambeau, Emmanuel Valentin, Melanie Rennou
  • Patent number: 9637554
    Abstract: Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets. A large-scale loss-of-function analysis of tyrosine kinases using RNA interference in the clinically relevant Erb-B2 positive, BT474 breast cancer cell line showed that Bruton's tyrosine kinase (BTK), a cytosolic, non-receptor tyrosine kinase that has been extensively studied for its role in B cell development, is required, in altered form, for BT474 breast cancer survival. This alternative form contains an amino-terminal extension that is also present in tumorigenic breast cells at significantly higher levels than in normal breast cells.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: May 2, 2017
    Assignee: The Research Foundation For The State University Of New York
    Inventors: Douglas S. Conklin, Cheryl Eifert, Antonis Kourtidis, Xianhui Wang, Leila Kokabee
  • Patent number: 9637555
    Abstract: We provide new monoclonal antibody inhibitors of coagulases for treatment of S. aureus. The monoclonal antibodies are useful in targeting the SC N-terminus and inhibiting prothrombin activation. The monoclonal antibodies are able to bind to and interfere with, modulate, and/or inhibit the binding interactions between the staphylocoagulase protein and its ligand protein prothrombin in blood and tissues. The antibodies are effective in inhibiting the activation of prothrombin.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: May 2, 2017
    Inventor: William R Church
  • Patent number: 9637556
    Abstract: This invention relates to methods for the generation of humanized antibodies, particularly a humanized antibody heavy chain protein and a humanized antibody light chain protein. The method comprises using cells that express or can be induced to express Activation Induced Cytidine Deaminase (AID).
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: May 2, 2017
    Assignee: AnaptysBio, Inc.
    Inventors: Peter M. Bowers, Andrew B. Cubitt, Robert A. Horlick
  • Patent number: 9637557
    Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes on a single molecule or located on different molecules. The methods combine efficient, high gene expression level, appropriate assembly, and ease of purification for the heteromultimeric proteins. The invention also provides methods of using these heteromultimeric proteins, and compositions, kits and articles of manufacture comprising these antibodies.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: May 2, 2017
    Assignee: Genentech, Inc.
    Inventors: Justin Scheer, Christoph Spiess, Daniel G. Yansura
  • Patent number: 9637558
    Abstract: A resin composition includes a cellulose derivative in which at least one hydroxyl group is substituted with an acetyl group in an amount ratio of 90% by weight or greater with respect to a total amount of the resin composition, wherein a melt flow rate (MFR) of the resin composition is in a range of 10 g/10 min to 20 g/10 min.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: May 2, 2017
    Assignee: FUJI XEROX CO., LTD.
    Inventor: Kenji Yao
  • Patent number: 9637559
    Abstract: Provided are an emulsifier derived from sugar polymer capable of successfully emulsifying even unsaturated oil, a production method therefore, and a production method for emulsion using the emulsifier. This emulsifier can be obtained by a production method including an emulsification improving step of improving the emulsification of sugar polymer particles dispersed in water. In this emulsification improving step, the emulsification of sugar polymer particles can be improved by an action of an emulsification aid that is at least water-soluble one kind selected from salts, an amphiphilic agent, saccharides, an organic acid, and an amino acid. Alternatively, the emulsification of sugar polymer particles can be improved by storing the sugar polymer particles dispersed in water at a low temperature of 10° C. or lower.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: May 2, 2017
    Assignee: KANAGAWA UNIVERSITY
    Inventors: Kazuo Tajima, Yoko Imai, Kaori Toyoda
  • Patent number: 9637560
    Abstract: A reactive extrusion process for the production of substituted polysaccharides, in particular, cellulose acetate, starch acetate, carboxymethyl cellulose, and carboxymethyl starch.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: May 2, 2017
    Assignee: NUtech Ventures
    Inventors: Milford Hanna, Pratik Bhandari
  • Patent number: 9637561
    Abstract: Food, consumer, and industrial product packaging materials are provided by embodiments of the present invention. Films and laminates based on a combination of negatively charged polysaccharides are provided as such packaging materials. The films can be prepared by mildly treating soft wood with steam followed by alkali extraction and enzymatic treatment. Negatively charged non-cellulosic polysaccharides are isolated with weight average molecular weight Mw higher than 10,000 g/mol and molecular structure comprising a xylan main chain substituted with more than 15 molar % of glucuronic acid and more than 5 molar % arabinose. The negatively charged non-cellulosic polysaccharides can be casted from water solution on a suitable carrier and surface acetylated or coated with acetylated polysaccharide to obtain oxygen and water barrier packaging laminate. Inventive packaging materials can have strength at break above 55 MPa, elongation to break above 2.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: May 2, 2017
    Assignee: Advanced Polymer Technology AB
    Inventor: Paul Gatenholm
  • Patent number: 9637562
    Abstract: Provided herein are organic solvent-based processes for the removal of rubber from aged briquettes made from compressed plant matter (briquettes) of non-Hevea plants. Also provided are aged briquettes made from the compressed plant matter of non-Hevea plants where the briquettes have been aged for either various time period after formation and the rubber within the briquette has retained its a molecular weight to within a specified range.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: May 2, 2017
    Assignee: Bridgestone Corporation
    Inventors: Yingyi Huang, Mark Smale, Robert White, Hiroshi Mouri, William Cole
  • Patent number: 9637563
    Abstract: A reactive surfactant composition comprising one or more kinds of reactive surfactants is disclosed that may be used as an emulsifier for emulsion polymerization, a dispersant for suspension polymerization, a nonaqueous dispersant, or a resin modifier.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: May 2, 2017
    Assignee: DAI-ICHI KOGYO SEIYAKU CO., LTD.
    Inventor: Asako Ogasawara
  • Patent number: 9637564
    Abstract: The present teachings show that it is possible to polymerize 1,1-disubstituted alkene compounds in an emulsion (for example using a water based carrier liquid), despite the possible reactions between the monomer and water. Polymerization of 1,1-disubstituted alkene compounds in an emulsion provides opportunities to better control the polymerization compared with bulk polymerization. The emulsion polymerization techniques can be employed for preparing homopolymers, copolymers (e.g., random copolymers), and block copolymers.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: May 2, 2017
    Assignee: SIRRUS, INC.
    Inventors: Peter Rulon Stevenson, Alexander R. Holzer, Aniruddha Sudhir Palsule, Jeffrey M. Sullivan
  • Patent number: 9637565
    Abstract: The present disclosure concerns embodiments of a polymeric compound, embodiments of a method for making and using the disclosed polymeric compound, and embodiments of a polymerizable composition. The polymeric compound is formed via photopolymerization of a photoinitiator and various polymerizable monomers. The disclosed polymeric compound and its components are useful as biomaterials, photolithography, and other applications. In particular disclosed embodiments, the photoinitiator comprises one or more chromophores capable of absorbing energy at particular wavelengths suitable for promoting formation of a carbanion capable of reacting with a polymerizable monomer.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 2, 2017
    Assignee: UVic Industry Partnerships Inc.
    Inventors: Peter Wan, Yu-Hsuan Wang
  • Patent number: 9637566
    Abstract: The present invention relates to a method for preparing a supported metallocene catalyst, and a method for preparing polyolefin using the same, in which the supported metallocene catalyst prepared from the simple process according to the method for preparing the supported metallocene catalyst of the present invention can apply to the polymerization of the polyolefin that is polymerized at low pressure or high pressure; the molecular weight distribution of polyolefin prepared can be easily controlled; and there are effects such that its catalyst activity is significantly higher than that of the existed supported metallocene catalyst, and the molecular weight distribution can be easily controlled.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: May 2, 2017
    Assignee: LG Chem, Ltd.
    Inventors: Hyuck-Ju Kwon, San-Ak Hwang, Dong-Gil Lee, Churl-Young Park
  • Patent number: 9637567
    Abstract: Spray-dried catalyst compositions comprising a transition metal complex and polymerization processes employing the same are disclosed herein. An embodiment provides a spray-dried catalyst composition comprising a transition metal catalyst component represented by the following formula: (I) and polymerization process employing the same.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: May 2, 2017
    Assignee: Univation Technologies, LLC
    Inventors: Wesley R. Mariott, Phuong A. Cao, Daniel P. Zilker, Jr., John H. Oskam, Cliff R. Mure
  • Patent number: 9637568
    Abstract: The present disclosure generally relates to a process for separating polymeric and gaseous components of a reaction mixture obtained by high-pressure polymerization of ethylenically unsaturated monomers in the presence of free-radical polymerization initiators into a gaseous fraction and a liquid fraction in a separation vessel, wherein the filling level of the liquid fraction in the separation vessel is measured by a radiometric level measurement system comprising at least two radioactive sources and at least three radiation detectors, and the filling level is controlled by a product discharge valve which operates based on data coming from the level measurement system.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: May 2, 2017
    Assignee: Basell Polyolefine GmbH
    Inventors: Danir Khayrullin, Michael Deuerling, Christoph Wolf, Erich Neumann, Claudio Fibla
  • Patent number: 9637569
    Abstract: The present disclosure relates to a vessel for separating, at a pressure of from 10 MPa to 50 MPa, a composition comprising liquid components and gaseous components into a liquid fraction and a gaseous fraction, wherein the separation vessel has a vertically arranged cylindrical shape, has at its top a manhole, which is surrounded by a thickened by a part of the separation vessel wall; and bears at least one bursting disc which is held by a bursting disc holder which is installed pressure-tight within a boring in the thickened part of the separation vessel wall.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: May 2, 2017
    Assignee: Basell Polyolefine GmbH
    Inventors: Erich Neumann, Danir Khayrullin, Claudio Fibla
  • Patent number: 9637570
    Abstract: Provided herein is a method for operating a slurry polymerization reaction system to reduce, inhibit, and/or prevent fouling in the polymer recovery and separation apparatus, including one or more portions of a high pressure flash tank. The method generally comprises polymerizing a monomer feed in a slurry polymerization reactor in the presence of catalyst and diluent to produce a polymerization effluent; continuously discharging at least a portion of said polymerization effluent from the reactor through a discharge valve; combining a catalyst poison stream with the polymerization effluent downstream of said discharge valve, wherein the catalyst poison stream comprises a catalyst poison that is a gas at standard conditions; and flashing the combination of polymerization effluent and catalyst poison stream in a first flash tank.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: May 2, 2017
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventor: Thomas W. Towles
  • Patent number: 9637571
    Abstract: The invention relates to a catalyst system comprising I. a solid reaction product obtained by reaction of: (a) a hydrocarbon solution comprising (1) an organic oxygen containing magnesium compound or a halogen containing magnesium compound and (2) an organic oxygen containing titanium compound and (b) a mixture comprising a metal compound having the formula MeRnX3-n wherein X is a halogenide, Me is a metal of Group III of Mendeleev's Periodic System of Chemical Elements, R is a hydrocarbon radical containing 1-10 carbon atoms and 0?n?3 and a silicon compound of formula RmSiCl4-m wherein 0?m?2 and R is a hydrocarbon radical containing 1-10 carbon atoms wherein the molar ratio of metal from (b): titanium from (a) is lower then 1:1 and II. an organoaluminium compound having the formula AlR3 in which R is a hydrocarbon radical containing 1-10 carbon atoms.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: May 2, 2017
    Assignee: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Nicolaas Hendrika Friederichs, Raymond Gerlofsma
  • Patent number: 9637572
    Abstract: The invention relates to a process for the continuous polymerization of one or more a-olefin monomers of which at least one is ethylene or propylene comprising the steps of: (1) feeding the one or more a-olefins to a vertically extended reactor suitable for the continuous fluidized bed polymerization of one or more a-olefin monomers of which at least one is ethylene or propylene, which reactor is operable in condensed mode, wherein the reactor comprises a distribution plate and an integral gas/liquid separator located below the distribution plate, (2) withdrawing the polyolefin from the reactor (3) withdrawing fluids from the top of the reactor, (4) cooling the fluids to below their dew point, resulting in a bottom recycle stream, (5) introducing the bottom recycle stream under the distribution plate, (6) separating at least part of the liquid from the bottom recycle stream using the integral separator to form a liquid phase and a gas/liquid phase, (7) feeding the liquid phase to an external pipe, (8) adding
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: May 2, 2017
    Assignees: SABIC GLOBAL TECHNOLOGIES B.V., SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Yahya Banat, Jose Fernando Cevallos-Candau
  • Patent number: 9637573
    Abstract: A polymer reactor-blend comprising at least a first component having a polydispersity index of greater than about 20 and is present in an amount of from about 1 wt. % to about 99 wt. % based on the total weight of the polymer and a second component having a polydispersity index of less than about 20 and is present in an amount of from about 1 wt. % to about 99 wt. % based on the total weight of the polymer wherein a molecular weight distribution of the second component lies within a molecular weight distribution of the first component.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: May 2, 2017
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Mark L. Hlavinka, Qing Yang, William B. Beaulieu, Paul J. Deslauriers
  • Patent number: 9637574
    Abstract: The present invention relates to a process for preparing alkyl methacrylates and their conversion products which can be used in a multitude of chemical synthesis processes which can lead to a wide variety of different further processing products, and to an apparatus for performing this process.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: May 2, 2017
    Assignee: Evonik Röhm GmbH
    Inventors: Udo Gropp, Robert Weber, Thomas Schaefer, Andreas Perl, Rudolf Sing, Thomas Mertz
  • Patent number: 9637575
    Abstract: An olefin polymerization catalyst component comprising an internal electron donor compound shown in formula (I) below is provided in this disclosure: wherein X is O, S, NRa, PRb, or POORc, Ra is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, Rb is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, linear or branched unsaturated or saturated alkoxy hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, Rc is independently hydrogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R1-R8 are identical or different hydrogen, halogen, linear or branched unsaturated or saturated C1-C30 alkyl, alone or in combination with C5-C30 substituted or unsubstituted 5-or 6-membered aliphatic or aromatic hydrocarbon rings, each of Ra, Rb, Rc, and/or R1-R8 are op
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: May 2, 2017
    Assignee: W. R. GRACE & CO. -CONN.
    Inventors: Binh Thanh Nguyen, Jonas Alves Fernandes
  • Patent number: 9637576
    Abstract: Disclosed are a device and a method for continuously polymerizing polybutene by removing halogen acid, which is included in a reaction raw material, by adsorbing the halogen acid using an adsorbent and then re-supplying the reaction raw material into a reactor. The device for re-circulating the raw material when manufacturing polybutene comprises a reactor, into which a catalyst and a reaction raw material (diluted with an inactive organic solvent) are supplied and polymerized to produce a reaction product; a neutralizing/washing tank for removing the catalyst from the reaction product and neutralizing the reaction product; a separation tank for separating the reaction product into organic compounds and water; a C4 distillation column for distilling an unreacted raw material and the inactive organic solvent from the organic compounds; and an impurity adsorption column for removing halogen acid from the distilled unreacted raw material and the inactive organic solvent using an adsorbent.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: May 2, 2017
    Assignee: DAELIM INDUSTRIAL CO., LTD.
    Inventors: Myeong Seok Kim, Min Sup Park, Kyoung Tae Min
  • Patent number: 9637577
    Abstract: A mixed PTFE powder according to the present invention is prepared by the steps of preparing a PTFE mixed dispersion by dispersing MoS2, Al2O3, and Al(OH)3 in a PTFE emulsion; dehydrating the PTFE mixed dispersion by adding Na2CO3 into the PTFE mixed dispersion to form a cake type compound; preparing an ingot by drying the cake type compound for about 16 to 24 hours at the temperature of about 120 to 190° C.; and pulverizing the ingot in a 30-35 mesh vibrating net. An HDME PTFE yarn according to the present invention is prepared by the steps of preparing the mixed PTFE powder; adding kerosene of about 18 to 25 wt. % as solvent to the mixed PTFE powder and maintaining the resultant for about 40 to 50 hours at the temperature of about 30 to 50° C.; extruding the resulting mixed PTFE into the form of rod at about 70 to 90° C.; calendering the rod into the form of sheet at about 100 to 150° C., the width of the sheet being about 100 to 300 mm and the thickness about 0.3 to 0.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: May 2, 2017
    Assignee: Ji Joong Hae Ind. Co., Ltd.
    Inventor: Kwang Huh
  • Patent number: 9637578
    Abstract: A polymerizable compound is provided having suitable polymerization reactivity, high conversion and high compatibility in a liquid crystal composition, a polymerizable composition containing the compound, a liquid crystal composite prepared using the composition, and a liquid crystal display device having the composite. The polymerizable compound has at least one monovalent group (A). The polymerizable composition contains the compound. The liquid crystal composition and the liquid crystal composite is prepared using the polymerizable composition. The liquid crystal display device has the liquid crystal composite. In the monovalent group (A), R1 and R2 are independently alkyl having 1 to 3 carbons, and in the alkyl, at least one of hydrogen may be replaced by fluorine, and R3 is hydrogen or methyl.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: May 2, 2017
    Assignees: JNC CORPORATION, JNC PETROCHEMICAL CORPORATION
    Inventors: Yasuyuki Gotoh, Kenji Hirata
  • Patent number: 9637579
    Abstract: The present invention relates to an elastic terpolymer which can satisfy excellent processability and elasticity (flexibility) at the same time, and a preparation method thereof. The elastic terpolymer is a copolymer of 40 to 70 weight % of ethylene, 15 to 55 weight % of a C3-C20 alpha-olefin, and 0.5 to 20 weight % of a diene obtained in the presence of a group 4 transition metal catalyst, of which i) the weight average molecular weight measured by GPC is 100,000 to 500,000, and ii) ? tan ?, the difference between the tan ? values at the angular frequencies of 0.2 rad/s and 100.0 rad/s, is 0.5 or less that is measured at 100° C. by using a rubber process analyzer.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: May 2, 2017
    Assignee: LG Chem, Ltd.
    Inventors: Sung-Cheol Yoon, Sung-Ho Park, Jun-Seok Ko, Soo-Young Choi
  • Patent number: 9637580
    Abstract: Provided is a method of preparing a vinyl chloride-based resin that includes preparing slurry through suspension polymerization by mixing a monomer, an oil soluble initiator, a dispersant, and an additive including an emulsifier, a water-soluble initiator, or a combination thereof, wherein the monomer includes vinyl chloride, an unsaturated carboxylic acid-based compound, and an ethylenic unsaturated compound that is copolymerizable therewith, and the emulsifier includes an anionic emulsifier, a non-ionic emulsifier, or a combination thereof.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: May 2, 2017
    Assignee: HANWHA CHEMICAL CORPORATION
    Inventors: Jeong Hwan Ko, Paul Kang, Ji Won Kim, Hyung Hoon Sim
  • Patent number: 9637581
    Abstract: A photocurable or thermally curable thiosulfate-containing polymer has (a) recurring units and (d) recurring units, shown as either Structure (I) or (II) and Structure (V) below: R represents the organic polymer backbone, G is a single bond or divalent linking group, Q+ is an organic charge balancing cation, M represents a charge balancing cation, and “a” represents at least 0.5 mol % and to 99.5 mol % of (a) recurring units; R? represents the organic polymer backbone, G? is a carbonyloxy group, R3 comprises a monovalent linear, branched, or carbocyclic non-aromatic hydrocarbon group having 1 to 18 carbon atoms, or it comprises a phenyl group having one or more such substituents, and “d” represents at least 0.5 mol % and to 99.5 mol % of (d) recurring units. These thiosulfate-containing polymers can be used to made dielectric compositions and gate dielectric layers in various devices.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: May 2, 2017
    Assignee: Eastman Kodak Company
    Inventors: Deepak Shukla, Kevin M. Donovan, Mark R. Mis
  • Patent number: 9637582
    Abstract: The invention provides an actinically-polymerizable amphiphilic polysiloxane which comprises a polysiloxane polymer chain comprising a polylsiloxane segments comprising at least one siloxane unit having a low molecular weight hydrophilic polymer chain connected with a silicone atom of the siloxane unit, and (meth)acrylamido groups each covalently bonded to one of the ends of the polysiloxane polymer chain and/or to the end of one of low molecular weight hydrophilic polymer chains each connected with one silicone atom. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises repeating units derived from an actinically-polymerizable amphiphilic polysiloxane of the invention.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: May 2, 2017
    Assignee: Novartis AG
    Inventors: Frank Chang, Jinyu Huang, Venkat Shankar
  • Patent number: 9637583
    Abstract: The present invention provides a transparent acrylonitrile-butadiene-styrene (ABS) resin and a transparent ABS resin composition. Specifically, according to the present invention, a transparent ABS resin and a transparent ABS resin composition, which have excellent transparency and impact resistance, can be provided by minimizing the degree of impregnation of a styrene monomer into a polybutadiene rubber latex while allowing the styrene monomer to constitute a graft shell to thereby effectively form the graft shell. Particularly, according to the present invention, a transparent ABS resin composition having high transparency and impact resistance can be provided, despite applying a reducing agent and Fe ions, which adversely affected the transparency of ABS resin in the prior art, to ABS resin.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: May 2, 2017
    Assignee: LG CHEM, LTD.
    Inventors: Seok Goo Jang, Sang Hoo Park, Roo Da Lee, Won Seok Lee, Jeong Su Choi, Jeun Hoon Yoo
  • Patent number: 9637584
    Abstract: Provided is a method for producing a molded product comprising a step for preparing a polymerizable composition for optical materials and a step for curing the polymerizable composition for optical materials to produce the molded product. The step for preparing the polymerizable composition for optical materials comprises a step for preparing a defined polythiol compound and a step for preparing the polymerizable composition for optical materials from the polythiol compound. The step for preparing the defined polythiol compound comprises reacting 2-mercaptoethanol with a defined epihalohydrin compound at a temperature of 10° C. to 50° C.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: May 2, 2017
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Masaru Kawaguchi, Takeshi Nishimura
  • Patent number: 9637585
    Abstract: The subject disclosure provides a viscoelastic polyurethane foam and a method of forming the viscoelastic polyurethane foam. The viscoelastic polyurethane foam comprises the reaction product of a toluene diisocyanate and an isocyanate reactive component. The isocyanate reactive component comprises a first polyether triol, a second polyether triol, an amino alcohol chain extender, and a hydrolyzable polyether polydimethylsiloxane copolymer. The first polyether triol has a weight-average molecular weight of from 500 to 5,000 g/mol, at least 60 parts by weight ethyleneoxy units, based on the total weight of the first polyether triol, and at least 10% ethyleneoxy end caps. The second polyether triol, which is different from the first polyether triol, has a weight-average molecular weight of from 5,000 to 10,000 g/mol and at least 80% ethyleneoxy end caps.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: May 2, 2017
    Assignee: BASF SE
    Inventors: Theodore M. Smiecinski, Chad Alan Rogers
  • Patent number: 9637586
    Abstract: The present invention provided a high temperature resistant epoxy resins for producing hollow fiber membrane modules for high temperature gas separation applications such as for natural gas upgrading and hydrogen purifications. This invention also relates to a hollow fiber membrane module comprising a bundle of multiple high performance hollow fiber membranes and a tube sheet formed by a high temperature resistant cured epoxy resin that is used to fix and bound said bundle of multiple high performance hollow fiber membranes. The invention also provides a process for separating at least one gas from a mixture of gases using the hollow fiber membrane modules comprising a bundle of multiple high performance hollow fiber membranes and a tube sheet formed by a high temperature resistant cured epoxy resin that is used to fix and bound said bundle of multiple high performance hollow fiber membranes.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: May 2, 2017
    Assignee: UOP LLC
    Inventors: Chunqing Liu, Howie Q. Tran, Travis C. Bowen
  • Patent number: 9637587
    Abstract: Disclosed is a method to prepare a polylactic acid comprising the steps of performing a ring opening polymerization using a catalyst and either a catalyst killer compound or an endcapping additive to obtain a raw polylactic acid of MW greater than 10,000 g/mol, purifying the raw polylactic acid by removing and separating low boiling compounds comprising lactide and impurities from the raw polylactic acid by devolatization of the low boiling compounds as a gas phase stream, and purifying the lactide from the devolatization and removing the impurities from the gas phase stream of evaporated low boiling compounds by means of crystallization by desublimation from the gas phase, wherein the lactide is purified and the removed impurities include a catalyst residue and a compound containing at least one hydroxyl group such that the purified lactide is then polymerized by feeding it back into the ring opening polymerization.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: May 2, 2017
    Assignee: Sulzer Chemtech AG
    Inventors: Manfred Stepanski, Francois Loviat, Andrzej Kuszlik