Abstract: Methods for identifying compounds that modulate cellular responses stimulated by IgE, which include providing an impedance-based system that monitors cell-substrate impedance of cells on a substrate; introducing cells to the substrate of the system; adding at least one test compound and IgE to the cells, wherein the at least one test compound is suspected of modulating cell responses stimulated by the IgE; adding an antigen to the cells; monitoring the cell-substrate impedance of cells on the substrate; and analyzing the cell-substrate impedance to evaluate whether the at least one test compound alters a cellular response to stimulation with the IgE.

Abstract: Methods are disclosed to detect, characterize, measure, and quantify human and humanized antibodies, and their conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples.

Abstract: The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a first neurovascular biomarker of lymphatic activation and diagnosing the patient as having the chronic inflammatory disease if the tested level of the first neurovascular biomarker of lymphatic activation is less than a first normal level.

Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Interleukin-18-binding protein as diagnostic and prognostic biomarker assays in renal injuries.

Abstract: The present invention provides biomarkers of oxidative stress in subjects with Retinitis Pigmentosa and their use in identifying subjects in need of treatment and methods for staging the severity of the disease.

Abstract: A robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject is provided. With measurement of one or more autoantibodies to biomarkers in a biological fluid such as CSF or serum, the extent of neurological damage in a subject with an abnormal neurological condition is determined and subtypes thereof or tissue types subjected to damage are discerned.

Abstract: There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.

Abstract: The present invention relates to the field of biomarkers. More specifically, the present invention relates to assay reagents useful in detecting neurogranin. In a specific embodiment, the present invention provides an isolated antibody or fragment thereof that specifically binds to neurogranin. In another embodiment, the present invention provides a polynucleotide aptamer that specifically binds neurogranin.

Abstract: A method of calibrating a device for measuring the concentration of creatinine using one or more calibration solutions, the method comprising: receiving concentrations at an initial time of creatine, Cr, and/or creatinine, Crn, of the one or more calibration solutions; receiving outputs of the measuring device at the end time; calculating the concentration of Cr and/or Crn in the calibration solutions at an end time using a temperature model, wherein the temperature model indicates an estimation of the temperature of the calibration solutions from the initial time to the end time, and wherein the temperature model includes a variable parameter; and determining a relationship between the outputs of the measuring device and the calculated concentrations of Cr and/or Crn.

Abstract: The invention relates to a method of diagnosis or prognosis of an obliterative arteriopathy in a subject, comprising determining the expression level of adenosine A2A receptors expressed at the cell surface of peripheral blood mononuclear cells obtained from said subject. The invention also relates to an agonist-like monoclonal antibody directed to the human adenosine A2A receptor, useful for carrying out this method.

Abstract: The invention features systems and methods for the detection of analytes, particularly antigens, complement, and antibodies present in blood. The invention features a system for the detection of antigens, complement, and antibodies on the surface of RBCs and circulating antibodies in the blood.

Abstract: Disclosed is a method for analyzing a blood specimen, including the steps of: coagulating a blood specimen in the presence of an activating agent for fibrinolytic system to acquire a coagulation waveform; and acquiring information about fibrinolytic capacity of the blood specimen based on the acquired coagulation waveform.

Abstract: Provided are devices, systems and methods for evaluation of hemostasis. Also provided are sound focusing assemblies.

Abstract: Device (1) for the storage and selection of cartridges (20) that are pre-filled with reactive discs to be placed on a support of the type comprising a plurality of magazines (2) each able to store a cartridge (20) of discs, at least one magazine-holding support (3) and, for each support (3), drive means (4) for moving the magazine-holding support (3).

Abstract: An analyzer is disclosed. The analyzer comprises a rack slot configured to receive at least one rack, wherein the rack slot comprises a front end, at which the rack is manually loadable into the rack slot, and a rear end, which is opposite to the front end and at which the rack is fully receivable in the rack slot, and a spring device arranged at the rear end, wherein the spring device is configured to provide a biasing force towards the front end, wherein the biasing force is adapted to move the rack towards the front end if not fully received in the rack slot, wherein the spring device is configured to fix the rack in a final position if the rack is fully received in the rack slot. Further, a method for loading a rack into a rack slot of an analyzer and a system comprising an analyzer and a computer controller are disclosed.

Abstract: A sensor device is provided with a magnetic field sensitive element being positioned in a magnetic field of a magnet. The magnetic field sensitive element is configured to sense an orientation angle of the magnetic field in the range between 0° and 360° and generate a sensing signal. The electronic circuitry is configured to receive and process the sensing signal from the magnetic field sensitive element to generate an angle signal indicating the orientation angle of the magnetic field.

Abstract: Implementations of an accelerometer component may include: a first Z proof mass rotatable about a first axis and coupled to an anchor, the first Z proof mass including a first plurality of electrodes. Implementations may include a second Z proof mass rotatable about the first axis and coupled to the anchor, the second Z proof mass including a second plurality of electrodes. An X-axis accelerometer subcomponent may be located within a perimeter of the first Z proof mass, and a Y-axis accelerometer subcomponent may be located within a perimeter of the second Z proof mass. The first plurality of electrodes and the second plurality of electrodes may be symmetrical about each of the first axis, a second axis perpendicular to the first axis, a third axis diagonal to the first axis and second axis, and a fourth axis diagonal to the first axis and second axis.

Abstract: A method of scanning probe microscopy includes supplying heat to a scanning probe. The method also includes receiving a scanning probe deflection signal, where the scanning probe deflection signal is indicative of a magnitude of deflection of the scanning probe when the scanning probe is engaged with a sample. A fourth harmonic signal is separated from the scanning probe deflection signal, and an ionic character of the sample is measured using the fourth harmonic signal.

Abstract: A probe card includes a substrate module having an installation hole and a first stair-shaped structure provided on two stairs thereof with a first connection surface and a first transmission surface having a first contact pad, a probe module having a probe and a second stair-shaped structure provided on two stairs thereof with a second connection surface and a second transmission surface having a second contact pad electrically connected with the probe, and a pressing member. The probe module is disposed in the installation hole so that the first and second connection surfaces are connected and the first and second transmission surfaces are opposite. The pressing member is detachably pressed on the probe module to press the second connection surface against the first connection surface and make the first and second contact pads electrically connected.

Abstract: A test device for testing electric properties of an object. The test device includes an object support unit configured to support an object; a cover unit configured to include a cover body coupled to the object support unit and a pusher supported by the cover body so as to move toward and away from the object; and a pressure adjuster configured to include a multi-stage adjusting cam which is rotatably provided in the cover body while contacting the pusher and has a multi-stage contact pressing portion with contact radii varied depending on rotated angles so that the pusher can be in a moving-back position and be positioned at a plurality of pressing distances from the cover body, and an operation unit which operates the multi-stage adjusting cam.

Abstract: The invention provides a testing probe, which includes a base, an elastic extensible element and a probe needle, the probe needle being disposed on the base through the elastic extensible element, and the elastic extensible element being in a stretched state. By the testing probe provided by the invention, only coating silver adhesive on the testing area of the liquid crystal screen previously is needed, and the steps of making solder wire, fixing solder wire, etc. are not needed any more. Therefore not only the preparation before testing can be simplified largely, but also reliability of connection is ensured, so as to reduce testing time largely and improve testing efficiency. The invention further provides a testing device including the above testing probe.

Abstract: A stack type test interface board assembly is provided herein, which comprises: a space transform board having a narrow pitch transform board and a wide pitch transform board, a plurality of first connection nodes disposed on a side of the narrow pitch transform board to be electrically connected to a finished or semi-finished semiconductor product, a plurality of second connection nodes disposed on a side of the wide pitch transform board, and a printed circuit board where a side thereof is electrically connected to the plurality of the second connection nodes. The narrow pitch transform board and the wide pitch transform board are assembled in perpendicular stack into the space transform board. A pitch between each two of the plurality of the first connection nodes is smaller than a pitch between each two of the plurality of the second connection nodes.

Abstract: Techniques for identifying electrical theft are described herein. In an example, a secondary voltage of a transformer may be inferred by repeated voltage and current measurement at each meter associated with the transformer. A difference in measured voltage values, divided by a difference in measured current values, estimates impedance at the meter. The calculated impedance, together with measured voltage and current values, determine a voltage at the transformer secondary. Such voltages calculated by each meter associated with a transformer may be averaged, to indicate the transformer secondary voltage. A transformer having lower-than-expected secondary voltage is identified, based in part on comparison to the secondary voltages of other transformers. Each meter associated with the identified transformer may be evaluated to determine if the unexpected voltage is due to a load on the transformer. If a load did not result in the unexpected secondary voltage, power diversion may be reported.

Abstract: A sensor, for measuring current in a conductor, has a stack with at least one isolation layer and at least two metallization layers stacked in a z direction, a first winding of conductive material and a second winding of conductive material, the first and second winding each having first and second parts formed in a metallization layer in the stack and mainly extending respectively in y and z directions and respectively having first and second centers of gravity. The first and second centers of gravity are respectively in first and second planes, wherein the first plane intersects with the second plane in a common intersection line in the second direction. The z direction and the y direction are orthogonal. The sensor has measurer configured to measure current through the first and second winding.

Abstract: A current sensor includes a current sense coil disposed about a conductive lead, the current sense coil configured to sense a current passing through the conductive lead. The current sense coil includes: a first outer coil configured to detect a first magnetic field generated by the current; a second outer coil configured to detect the first magnetic field, the second outer coil further configured to cancel an electrical field induced in the first outer coil; and an inner conductor disposed between the first outer coil and the second outer coil, the inner conductor configured to detect a second magnetic field generated by the current.

Abstract: A current sensor includes a two-piece ferromagnetic core clamped together over a wire to be measured by a housing to form a ferromagnetic cylinder that concentrates the magnetic flux surrounding the electrical wire to be measured. By directing the magnetic flux to a Hall effect sensor, the current can be measured in the wire without cutting or modifying the wire.

Abstract: An electric current detection device includes magnetism detector elements for detecting a strength of a magnetic field generated by an electric current flowing through an electric current path, a detection circuit for detecting a magnitude of an electric current flowing through the electric current path based on an output of the magnetism detector elements, and plural wires that are connected to the magnetism detector elements and extend in a direction away from the electric current path. The magnetism detector elements are arranged such that a direction of a magneto-sensitive axis thereof lies on a first plane parallel to a current-carrying direction of the electric current path and parallel to an extending direction of the plurality of wires. The plural wires are arranged on a same plane of a second plane orthogonal to the first plane.

Abstract: It is proposed to use a spun birefringent fiber for a current sensor or magnetic field sensor. The fiber has a birefringence that increases with temperature. In this case, the temperature dependence of the fiber's sensitivity to magnetic fields counteracts the temperature dependence of the fiber's Verdet constant, which allows to design current and field sensors that have reduced temperature dependence.

Abstract: A voltage detection circuit includes an inductor connected to connection portions configured to input an alternating-current voltage, an inductor magnetic-field coupled to the inductor, a capacitor connected in parallel to the inductor and constituting a secondary-side resonant circuit with the inductor, and a voltage detector configured to detect an output voltage from the secondary-side resonant circuit. Therefore, a voltage detection circuit, a power transmission device, and a power transmission system capable of detecting an alternating-current voltage with high detection sensitivity irrespective of the potential of a power transmission line are provided.

Abstract: The systems and methods of the present disclosure use measurement circuitry that includes first and second circuits, a selecting circuit, a determination circuit, and a setting circuit. Each of the first and second circuits measures voltage or current sensed by a sensor. The selecting circuit selects the first circuit to provide the measured voltage or current values. The determination circuit determines whether the measured voltage or current values reach a predetermined level. The setting circuit changes a setting of the second circuit from a first setting to a second setting if the measured voltage or current values reach the predetermined level. The selecting circuit selects the second circuit to provide the measured voltage or current values when a first predetermined time elapses after changing the setting of the second circuit. The selecting circuit also changes a setting of the first circuit from the first setting to the second setting after selecting the second circuit.

Abstract: Example implementations relate to circuits. For example, an implementation includes a detection circuit including a comparator circuit. The comparator circuit includes a first input terminal, a second input terminal, and an output terminal. The detection circuit also includes a reference voltage circuit to provide a set point voltage to the comparator circuit via the first input terminal. The detection circuit further includes a diode to reduce the set point voltage from a first magnitude to a second magnitude when the first magnitude is equal to or lower than a magnitude of the load voltage.

Abstract: A personal mobile system for detecting unsafe electrical power levels. Magnetic sensors detect a magnitude of a magnetic field produced by a power line. A GPS determines the location of the detected the magnetic field. A distance from the location of the detected the magnetic field is determined. In response to determining that the magnitude of the detected magnetic field produced by the power line exceeds the stored electrical power level threshold, based on the determined distance, an alert module produces an alert on the personal mobile system.

Abstract: A remote monitoring system and method for electricity demand of a fused magnesium furnace group. The system has a data acquisition device, a local PC, a cloud server and a remote PC. The data acquisition device has a voltage transformer, a current transformer, an active power transducer, a first slave computer, a plurality of multi-purpose electronic measuring instruments and a second slave computer. The method includes acquiring smelting current and smelting power of each fused magnesium furnace and electricity demand of the furnace group, controlling the switch off/on of each fused magnesium furnace according to the smelting current and the smelting power of each fused magnesium furnace and the electricity demand of the furnace group, sending basic monitoring data to the local PC, and achieving data exchange between the local PC and the remote PC through the Zookeeper technology.

Abstract: A method performs state estimation of a distribution network based on real time measurement values. The method includes calculating load scaling factors at least for non-redundantly measurable parts of the distribution network, determining whether each of the load scaling factors related to a non-redundantly measurable part of the distribution network is within a given range (RLSF), and discarding the measurement values related to the corresponding scaling factor for all load scaling factors outside the given range (RLSF). The network state of the distribution network is then estimated based on the remaining measurement values.

Abstract: Provided is a flexible, durable capacitive sensor that achieves high flexibility in designing wiring arrangement. A capacitive sensor includes a dielectric layer and a plurality of electrode units placed on both sides of the dielectric layer in the front-back direction. The electrode unit includes an insulating layer having through holes extending therethrough in the front-rear direction, electrode layers placed on one side of the insulating layer in the front-back direction, and jumper wiring layers placed on the other side of the insulating layer in the front-back direction and electrically connected to the electrode layers through the through holes. The insulating layer has an elongation at break of 60% or more, a tension set of less than 5%, and a volume resistivity of 1.0×1010 ?·cm or more.

Abstract: A device comprises a circuit board, a Rogowski coil on the circuit board, persistent data storage on the circuit board, and a control circuit on the circuit board for collecting values representing current sensed by the coil, and storing the values in the persistent memory.

Abstract: A patch cord, a management system and a management method thereof are provided. The patch cord (10) comprises a connection line portion (11), a first connector (21) arranged at a first end of the connection line portion (11), a second connector (22) arranged at a second end of the connection line portion (11), a first communication unit (31) arranged at near the first connector (21) including a first identifier and a second communication unit (32) arranged near the second connector (22) including a second identifier, wherein the first and second identifiers contain unique identify information for identifying the first connector and the second connector, respectively, and wherein the first identifier is different from the second identifier. The management system and the management method can differentiate connectors at the both ends of the patch cord by self-identification.

Abstract: The present disclosure illustrates the errors that are encountered when using both single-ended and double-ended normal-mode fault location calculations when a fault occurs in a pole-open condition. The disclosure provides systems and methods for accurately calculating the location of faults that occur during pole-open conditions, including single-ended approaches and double-ended approaches.

Abstract: The terminals of a device under test are temporarily electrically connected to corresponding contact pads on a load board by a series of electrically conductive pin pairs. The pin pairs are held in place by an interposer membrane that includes a top contact plate facing the device under test, a bottom contact plate facing the load board, and a vertically resilient, non-conductive member between the top and bottom contact plates. Each pin pair includes a top and bottom pin, which extend beyond the top and bottom contact plates, respectively, toward the device under test and the load board, respectively. The top and bottom pins contact each other at an interface that is inclined with respect to the membrane surface normal. When compressed longitudinally, the pins translate toward each other by sliding along the interface. The sliding is largely longitudinal, with a small and desirable lateral component determined by the inclination of the interface.

Abstract: The disclosure describes a novel method and apparatus for allowing response data output from the scan outputs of a circuit under test to be formatted and applied as stimulus data input to the scan inputs of the circuit under test. Also the disclosure described a novel method and apparatus for allowing the response data output from the scan outputs of a circuit under test to be formatted and used as expected data to compare against the response data output from the circuit under test. Additional embodiments are also provided and described in the disclosure.

Abstract: This disclosure describes a test architecture that supports a common approach to testing individual die and dies in a 3D stack arrangement. The test architecture uses an improved TAP design to facilitate the testing of parallel test circuits within the die.

Abstract: The disclosure describes a novel method and apparatus for improving interposers that connected stacked die assemblies to system substrates. The improvement includes the addition of IEEE 1149.1 circuitry within interposers to allow simplifying interconnect testing of digital and analog signal connections between the interposer and system substrate it is attached too. The improvement also includes the additional 1149.1 controlled circuitry that allows real time monitoring of voltage supply and ground buses in the interposer. The improvement also includes the additional of 1149.1 controlled circuitry that allows real time monitoring of functional digital and analog input and output signals in the interposer. The improvement also provides the ability to selectively serially link the 1149.1 circuitry in the interposer with 1149.1 circuitry in the die of the stack.

Abstract: A technique for testing an electronic UUT by a test apparatus includes obtaining multiple DFTs of a test signal received from the UUT with the test apparatus configured differently for obtaining each DFT. The resulting DFTs include both valid content representing the test signal and invalid content introduced by the test apparatus. The improved technique suppresses the invalid content by generating a corrected DFT, which provides minimum magnitude values for corresponding frequencies relative to the test signal across the multiple DFTs.

Abstract: An integrated circuit, comprising functional circuitry and testing circuitry. A first set of pads is operable in a first state for communicating testing signals to the testing circuitry and operable in a second state for communicating input/output signals to the functional circuitry. A second set of pads, differing from the first set of pads, is operable in the second state for communicating testing signals to the testing circuitry for testing signals associated in the second state with the first set of pads.

Abstract: A semiconductor device, for example an integrated circuit such as a microcontroller (MCU) or a digital signal processor (DSP), includes a semiconductor die coupled with a power supply line, a debug module coupled with the semiconductor die to exchange semiconductor die debug command and data signals with the semiconductor die, and a modem coupled with the power supply line. The debug module is arranged to convey the semiconductor die debug command and data signals over the power supply line.

Abstract: A semiconductor device, a battery monitoring system, and a detection method are provided. An end of the capacitor (C1) is switchable to be connected to one of a positive electrode and a negative electrode of a battery cell. An end of a capacitor (C2) is switchable to be connected to the other electrode. A comparator includes a non-inverted input terminal connectable to the battery cell via the capacitor (C1), and an inverted input terminal connectable to the battery cell via the capacitor (C2). A capacitor (C3) is located between a node (inp) and a switch (S1) that switches a connection state between a ground voltage source and any one of reference voltage sources. A capacitor (C4) is located between a node (inn) and a switch (S2) that switches a connection state between the ground voltage source and any one of the reference voltage sources.

Abstract: The overvoltage protection circuit according to an embodiment of the present invention includes: a voltage measurement unit for measuring the voltage of a battery; a power control unit that supplies power if the battery voltage value measured in the voltage measurement unit is equal to or greater than a first predetermined voltage value; and a cut-off circuit unit that receives power supplied from the power control unit and cuts off the charge of the battery if the voltage value of the battery is equal to or greater than a second predetermined voltage value that is higher than the first voltage value.

Abstract: A method for abnormality detection in an energy unit includes passively detecting an abnormality in an energy unit by detecting electromagnetic radiation generated by the abnormality, the energy unit comprising at least one of an electrical energy unit and an electrochemical energy unit. A method for detecting an abnormality in an energy unit includes (a) applying a signal to the energy unit, (b) performing a plurality of measurements, at a respective plurality of different locations within the energy unit, of a response of the energy unit to the signal, and (c) processing the plurality of measurements to identify the abnormality.

Abstract: A parameter estimation device for a battery capable of reducing an error in estimate of an internal resistance caused by a temperature difference is provided. In a parameter estimation device for a battery (1) for sequentially estimating parameters including a resistance in an equivalent circuit model (41) of the battery based on a temperature of the battery and at least one of a voltage of the battery and a current of the battery, as a resistance value of the resistance in the equivalent circuit model of the battery, a resistance value at a predetermined temperature is estimated, and a resistance value at a present temperature is calculated based on the resistance value at the predetermined temperature and the present temperature.

Abstract: A charge/discharge condition adoptable in a secondary battery of high-temperature operation type is calculated by a small amount of calculations. A resource matrix includes a plurality of state indicators and a plurality of charge/discharge conditions. The resource matrix is referred to and two or more state indicators related to an input state indicator so as to satisfy a condition are selected from the plurality of state indicators. A charge/discharge condition corresponding to each of the two or more selected state indicators are extracted from the plurality of charge/discharge conditions, so that two or more charge/discharge conditions are extracted. Interpolation is performed in the two or more selected state indicators and the two or more extracted charge/discharge conditions, so that a charge/discharge condition adoptable in a secondary battery in a case where a state of the secondary battery is indicated by the input state indicator, is calculated.