Abstract: Provided herein is an integrated wireless patch comprising a contact layer, an electronics layer, and a battery layer. The contact layer is a substrate having gel cutouts. The electronics layer can be folded into contact with the contact layer. The battery layer can be folded into contact with the electronic layer. Further provided herein is a method of manufacturing a wireless integrated patch comprising folding a substrate comprising at least one cutout, at least one contact disk in communication with a surface of a patient through the cutout, and battery terminals, wherein the at least one cutout, the at least on contact, and the battery terminals are adaptable to be located in different layers after the substrate is folded.

Abstract: A muscle fatigue output device is provided with a myoelectric measurement unit that acquires myoelectricity of a user, and a main control unit that determines fatigue of a muscle of the user on the basis of the myoelectricity. The main control unit (a) uses the myoelectricity to acquire a value for a frequency characteristic of the myoelectricity, (b) uses the myoelectricity to acquire a value for an amplitude characteristic of the myoelectricity, (c) acquires a ratio between the value for the frequency characteristic and the value for the amplitude characteristic as an index for the fatigue of the muscle of the user, and (d) outputs information regarding the fatigue of the muscle of the user, on the basis of the index for the fatigue of the muscle of the user.

Abstract: The invention provides improved devices and apparatuses and related methods for sensing differences in pressure or other parameters in the environment of the body of a patient during passage of the device through one or more tissues. In one aspect, the devices and apparatuses of the invention are configured to sense differences in the environment of the body of the patient as the device passes through tissue adjacent to the epidural space to tissue of the epidural space. In one aspect, a dual cannula device comprising one or more sensors connected to a signaling component is provided for sensing passage into of the device into the epidural space and positioning therein. Methods of using same are also provided.

Abstract: A detection system can include a device, a circuit, and at least one indicator. The device can include polymer needle having a distal end and a proximal end. A needle lumen can be extended along a longitudinal axis of the polymer needle. The distal end can include an insertion tip. An elongate sleeve can include a first end and a second end. The polymer needle can be located within an inner bore of the elongate sleeve. The insertion tip of the polymer needle can be disposed at a distance from the elongate sleeve. A first electrode can be coupled to the device and a second electrode can be electrically isolated from the first electrode. The circuit can be configured to provide a signal based on an electrical characteristic between the first electrode and the second electrode. At least one indicator can be communicatively coupled to the circuit and configured to provide an output based on the signal.

Abstract: Some embodiments are directed to a portable electronic device for analyzing an analyte. The portable electronic device includes a housing, an adapter detachably coupled to the housing and a processor disposed in the housing. The adapter includes a body defining an opening for receiving a test strip and an interface port disposed within the body. The interface port is configured to read a signal from the test strip. The processor is communicably coupled to the interface port. The processor is configured to determine at least one parameter of the analyte based on the signal received from the interface port.

Abstract: Biometric sensor systems are provided for identifying fundamental heart rate harmonics within noisy sensor signals. The system calculates a local signal-to-noise ratio for one or more identified frequency bands received in a biometric signal. The identified frequency bands are ranked based upon the calculated local signal-to-noise ratio. The fundamental heart rate is identified based upon the ranking of the identified frequency bands.

Abstract: A user interface allows clinical personnel to view predictive risk indices and related physiological data. When a risk index indicates a dangerous condition, the user interface may generate an alarm for routing to an appropriate caregiver. In addition to displaying patient-specific data, comparisons may be provided between the patient and a patient population for those signals, allowing easy recognition of deviations from the norm for the patient population.

Abstract: The present system discloses a data acquisition server for monitoring sensor data on a patient, the server controlling a plurality of sensors, each comprising a data acquisition circuit for measuring data on the patient, the server being operable to receive selection of a first sensor for capturing a first data on a patient, retrieve in a sensor database controlled by the data acquisition server a first mapping rule associated to the first sensor, the first mapping rule defining among the plurality of sensors a subset of secondary sensors linked to the first sensor, a sensor being a secondary sensor to the first sensor when measuring a type of data that characterizes the context of measurement by the first sensor, controlling the data acquisition circuit of the first sensor to capture first data, controlling the data acquisition circuit of each secondary sensors from the subset of sensors, to capture secondary data, retrieve in the sensor database a first rendering rule associated to the first sensor, the fir

Abstract: The present disclosure provides a computed tomography apparatus and a method for capturing a tomographic image by the same. The device includes: a radiation source configured to emit X rays; a radiation source window; a baffle having a through-hole therein; a control module connected to the baffle via a drive device, configured to control a rotation center of a rotation arm of the apparatus according to a preset photographing condition to determine a photographing position to be captured, and to regulate the baffle via the drive device according to a position of a partial area of a target object when the photographing position is the partial area; and the area array detector configured to convert received X rays penetrating through the through-hole and the partial area to a projection image.

Abstract: A method is described for positioning of an examination object for an imaging method. The method is used to record an external image of externally visible features of the examination object. The recording of the external image is used as the basis for determining a position and/or orientation of at least one part of the examination object assigned to the imaged features. Subsequently, a check is performed as to whether the determined position and/or orientation of the at least one part of the examination object conforms to a reference position and/or reference orientation. Finally, if the determined position and/or orientation of the at least one part of the examination object does not conform to the reference position and/or reference orientation, the position and/or orientation of the at least one part of the examination object is corrected. Also described is an object-positioning facility. Furthermore, an imaging medical facility is described.

Abstract: The present disclosure relates to systems and methods for positioning an X-ray scanner. The systems may perform the methods to obtain one or more images relating to the target in the object; determine one or more image target locations corresponding to the target based on the one or more images; determine a target position of the target based on the one or more image target locations corresponding to the target; and determine positioning information of an indicator or an X-ray source of the X-ray scanner based on the target position.

Abstract: In the present invention, a system and associated method is provided for image-guided navigation during a medical procedure. The system includes a movable gantry having an X-ray source, an X-ray detector and a laser disposed on the detector offset from the area of the detector receiving the beam from the source, a movable table and a system controller operably connected to the gantry, the X-ray source, the X-ray detector, the laser and the table. In the method, the controller determines an optimal trajectory for the insertion of an interventional device into the body to intersect the target, positions the gantry to locate the laser at a point where a laser beam is emitted from the laser along the optimal trajectory outside of the X-ray beam, and takes additional images during the procedure to show the position of the interventional device in the body as compared with the optimal trajectory.

Abstract: The invention relates to a method for providing a first and a second digital panoramic layer image optimized for a comparison, wherein the first and second panoramic layer images each have multiple projections detected and stored for them by means of at least one digital detector during an at least partial revolution of a recording unit around an object to be recorded, and the first and second panoramic layer images are each produced from the multiple projections in accordance with a computation code and by forming a panoramic layer. Differences between the first and second panoramic layer images are minimized by altering at least one parameter of the computation code for fresh production of the first and/or second panoramic layer image. In addition, the invention relates to a corresponding apparatus.

Abstract: An X-ray detector includes a detection unit to convert X-rays into a signal value and an evaluation unit. The detection unit and the evaluation unit are configured in a common component, the extent of the component along a first direction being not greater than the extent of the detection unit. The evaluation unit includes at least one correction unit to correct the signal values, a computation unit to control the correction, and a memory unit to store at least one correction parameter. The evaluation unit is designed such that the signal values are corrected as a function of the at least one correction parameter. A method and detector group are also disclosed.

Abstract: According to various aspects, exemplary embodiments are disclosed of systems that may be used for cooling objects, such as X-ray tubes and detectors, etc. Also disclosed are exemplary embodiments of methods for cooling objects, such as X-ray tubes and detectors, etc. For example, an exemplary embodiment includes a system that can be used to cool an X-ray tube and detector with one chiller. As another example, an exemplary embodiment of a method includes using one chiller to cool an X-ray tube and detector.

Abstract: A system for taking fluoroscopic images of large animals having a rotatable plate with a plurality of detectors disposed on the rotatable plate, wherein the detectors are arranged as spokes extending radially outwardly from a central rotational point on the rotatable plate with collimators disposed on the side edges of the spokes. A drive assembly rotates the plate about an axis extending through the central rotational point at a speed such that the duration of successive image frames corresponds to the time taken for each spoke of detectors to move to the position of an adjacent spoke of detectors.

Abstract: Adaptive imaging methods and systems for generating enhanced low light video of an object for medical visualization are disclosed and include acquiring, with an image acquisition assembly, a sequence of reference frames and/or a sequence of low light video frames depicting the object, assessing relative movement between the image acquisition assembly and the object based on at least a portion of the acquired sequence of reference video frames or the acquired sequence of low light video frames, adjusting a level of image processing of the low light video frames based at least in part on the relative movement between the image acquisition assembly and the object, and generating a characteristic low light video output from a quantity of the low light video frames, wherein the quantity of the low light video frames is based on the adjusted level of image processing of the low light video frames.

Abstract: A system, medium, and method including obtaining a plurality of positions for multiple components defined by a plan; obtaining a set of constraints that express limitations for the multiple components at the plurality of positions, the constraints being applicable to a plan where the multiple components synchronously change their positions with time to traverse a prescribed sequence of the plurality of positions, at least one of the multiple components being further constrained to change its position over time by staying within a predefined tolerance to a predefined smooth function of position over time between different positions; determining a trajectory of position and a minimum duration in which the multiple components completely synchronously traverse the prescribed sequence of positions while satisfying the constraints for the multiple components; and generating a record of the determined trajectory of position and the minimum duration for the plurality of components.

Abstract: An integrated interface of a detector module of a Positron Emission Tomography (PET) may include a power module, a clock module, a synchronization module, and a communication module. In one embodiment, Gigabit Ethernet, 10G Ethernet, Fast Ethernet (100M), 10M Ethernet or custom speed Ethernet based solution can be used in the communication module. In the power module, the power is can be transmitted by standard PoE (Power over Ethernet) method, while the clock can be recovered from Ethernet in the clock module. In the synchronization module, in one embodiment, the synchronization can be done through a dedicated package and/or IEEE1588. The integrated interface can be implemented in other systems. For example, it can be used in a gamma camera system or gamma probe, especially a dynamic gamma camera or handheld gamma camera.

Abstract: An apparatus for imaging tissue in three dimensions (e.g. ICE catheter) includes a shaft, a static imaging element (20) disposed within the shaft, an oscillating energy deflector (24) positioned within the beam path of the imaging element, and a drive assembly operable to oscillate the energy deflector. The imaging element can be acoustic or electromagnetic, and the energy deflector can be a prism, a lens or an acoustic mirror. By oscillating the energy deflector and/or by providing an asymmetric energy deflector, a plurality of two-dimensional image slices can be obtained. These image slices can then be assembled into a three-dimensional volumetric image.

Abstract: An ultrasound wireless probe adapter is presented. The adapter includes a first coupling unit configured to detachably couple the adapter to ultrasound probe assemblies, a second coupling unit configured to wirelessly couple the adapter to a smart device, and a microcontroller. The microcontroller is configured to wirelessly communicate with the smart device to accept user inputs, generate and transmit one of excitation signals and control and configuration signals to the ultrasound probe assemblies based on the user inputs and a category of the ultrasound probe assemblies to initiate emission of acoustic signals towards a region of interest in a subject, receive echo signals generated by the ultrasound probe assemblies in response to one of the transmitted excitation signals or the transmitted control and configuration signals, and process received beam signals based on a processing capability of the smart device to generate one of partially-processed image data and fully-processed image data.

Abstract: A transducer subassembly with combined imaging and therapeutic capabilities is disclosed. The subassembly includes heat sinks that are configured to maintain the transducer at a low operating temperature so that the transducer operates at high efficiency and also can handle a wider range of frequencies. The subassembly is also configured to allow cooling fluid to flow past the transducer element. One heat sink in the subassembly also acts as an acoustic matching layer and another heat sink acts as a backing Alternatively, the second heat sink which acts as a backing is optional. The transducer is configured to transmit at one power level for imaging, and at a second power level for ablating. The transducer may comprise sub-elements transmitting at different power levels. The subassembly may be operated at one power level for imaging and a second power level for ablating.

Abstract: A method includes receiving ultrasound echo signals produced in response to a pulsed ultrasound field interacting with anatomical tissue and flow of structure therein. The method further includes generating electrical signals indicative thereof. The method further includes beamforming the electrical signals producing beamformed data. The method further includes constructing a real-time image of the anatomical tissue with the beamformed data. The method further includes constructing a de-aliased color images of the flow with the beamformed data. The method further includes visually presenting the real-time image of the anatomical tissue with the de-aliased color images of the flow superimposed thereover.

Abstract: An apparatus for testing for streptococcal pharyngitis includes a tube having an open first end and a second end, and an opening on a side thereof, a dipstick inserted into the tube through the side opening, and an insert with a hole that can receive the dipstick and sized to nest the dipstick into the side opening of the tube. A swab at the end of the dipstick inside the tube receives microbes in a breath exhaled by a patient holding the first end of the tube to the patient's mouth. After being exhaled upon by the patient, the dipstick is removed for testing for the presence of microbes that cause streptococcal pharyngitis.

Abstract: A biomaterial collection device can include a wire that includes a functional member including a proximal end, a distal end, a first flat surface and a second flat surface opposing the first surface. The functional member can be configured to fit within a body lumen. The functional member can include binding elements configured to bind circulating biomolecules and cells. The functional member can include curved portions that form revolutions around the longitudinal axis of the device.

Abstract: A multi-functional handle manipulates a medical instrument and includes a body capable of being gripped by a hand of a user and further capable of being in communication with the medical instrument. In non-limiting exemplary embodiments, the handle may include one or more of a first trigger assembly, a second trigger assembly and a third trigger assembly. The body may also include a first portion and a second portion coupled thereto such that the second portion is displaced relative to the first portion. At least one of the first portion, second portion and first trigger assembly is capable of manipulating the medical instrument. Non-limiting exemplary embodiments also include one or more of a primary digit-receiving member, a secondary digit-receiving member, and a tertiary digit-supporting member for facilitating ergonomic operation of the handle.

Abstract: A braided vaso-occlusive member formed out of first plurality of filaments interwoven with a second plurality of filaments, wherein filaments of the first plurality are helically wound in a first rotational direction along an elongate axis of the braided member, and filaments of the second plurality are wound in a second rotational direction opposite the first rotational direction, such that filaments of the first plurality cross over and/or under filaments of the second plurality at each of a plurality cross-over locations axially spaced along the elongate axis of the braided member, wherein at each cross-over location, the filaments of the first plurality cross over at least two consecutive filaments of the second plurality, then cross under only a single filament of the second plurality, and then cross over at least two additional consecutive filaments of the second plurality.

Abstract: A surgical instrument with pressure sensing and vision feedback functions has an instrument body and a piezochromic device. The instrument body includes a work piece with a visible surface. The piezochromic device is disposed on the visible surface of the work piece of the instrument body and performs color change when the piezochromic device senses pressure. Therefore, when a doctor performs surgery using the surgical instrument, the doctor can directly see the piezochromic device. When the piezochromic device contacts other surgical instruments or presses organs or tissues within a patient's body, the piezochromic device will change color when the piezochromic device senses the pressure enabling the doctor to adjust the surgical instrument accordingly.

Abstract: A medical device may include a tool body and a handle. The handle may include a first body having a first coupling feature extending axially along the first body and a second body including a second coupling feature positioned within the first coupling feature. In a first orientation, the first body and second body may be rotatable and axially translatable relative to each other as a function of the first and second coupling features.

Abstract: Technologies are described for an endoscopic duct clearing system. A cannula can be shaped to pass through an endoscope within an esophagus, into a duodenum, and through an incision in a duodenal papilla. A capture basket may be deployed from a distal end of the cannula. A hand control at the proximate end of the cannula may be operable to position the distal end of the cannula from outside the endoscope into proximity of blockage material. A suction line may be coupled from a suction source to the proximate end of the cannula. A suction control may be coupled to the suction source. The suction control may be operable to adjust a level of suction drawn by the suction source through the distal end of the cannula. The suction control may be adjusted to draw the blockage material against or into the cannula for removal from the patient.

Abstract: An adhesive applicator (1) comprises a receiver (3) having a tubular body with a closed first end (13) and an opposed second end (15), the tubular body having a deformable wall (11), an adhesive composition contained within the tubular body, and an applicator tip (5) mounted on the tubular body and comprising a foam material (7) having an applicator (7a-7c) external of the applicator (1) for applying said adhesive, the applicator being such that deformation of the tubular body causes the adhesive to be expressed through the applicator tip (5), The foam material is a reticulated foam felt (7) and allows for relatively constant flow of the adhesive through the foam felt and to the applicator surface thereof over a wide range of viscosity conditions of the adhesive and pressure applied to the deformable body of the applicator (1).

Abstract: A spinal surgery retractor and method of use. The retractor includes a slotted keyway for integrating a keyed spinal distractor. The retractor and distractor combination slide together to displace a portion of the intervertebral disk space to restore or maintain intervertebral spacing and facilitate retraction of surrounding soft tissues while disk space surgery is performed. The distractor head and mating portion of the retractors have matching profiles that enable the retractor to maintain distraction of the vertebra after removal of the distractor portion of the tool, permitting access to increase at the operating site.

Abstract: An end effector for a surgical fastening device is provided. The end effector includes a body defining a longitudinal axis, one or more fasteners, an anvil, and a pusher. Each fastener has an unformed configuration and a formed configuration. Each fastener includes first and second arms that extend in opposite directions. The first arm has first and second elbow segments. The first elbow segment is configured to bend as the fastener is formed. The second elbow segment is configured to remain unbent as the fastener is formed. The pusher is configured to advance the fastener distally through the body and into engagement with the anvil to form the fastener against the anvil.

Abstract: A surgical circular stapler has a handle assembly, a shaft, a stapling assembly, a motor, a drive assembly, and a firing assembly. The shaft extends distally from the handle assembly. The stapling assembly is secured to a distal end of the shaft. Longitudinal translation of the firing assembly causes the stapling assembly to drive a plurality of staples in a circular array to secure two lumens of tissue together. The stapling assembly may further drive a blade to sever any excess tissue interior of the circular array of staples. The motor is operable to rotate the drive assembly to thereby translate the firing assembly. A resilient member biases the firing assembly proximally. Through cooperation between the firing assembly and the resilient member, the firing assembly is driven distally and proximally to complete a firing stroke in response to rotation of the drive assembly through a single revolution.

Abstract: A calibration system for a surgical instrument. The calibration system includes an actuator, such as a motor system and a flexible shaft. The calibration system also includes a surgical instrument actuatable by the actuator. The calibration system also include calibration data corresponding to the surgical instrument. A processor is configured to process the calibration data for determining a position of the surgical instrument. The calibration system may include a sensor configured to provide a signal corresponding to a movement of the actuator, the processor being further configured to process the signal for determining a position of the surgical instrument.

Abstract: Disclosed is a joining element (10), especially a suture material for surgical use. The joining element (10) is composed of a first material (12) that is essentially rigid during impingement by a relatively short-lasting tensile load on opposite sides as well as a second material (11) which is connected to the first material. The second material is substantially rigid during impingement by said tensile load on opposite sides while contracting slowly during a second period of time that is longer than the first period of time.

Abstract: An active anvil assembly for use in forming a looped suture is provided. The active anvil assembly includes an anvil member, a first sensor operably connected to the anvil member, and a control assembly. The first sensor is configured for measuring at least one of force, torque, and distance feedback. Also provided are systems and methods for forming a looped suture including an active anvil assembly.

Abstract: A stapling head assembly of a suturing and cutting apparatus for endoscopic surgery includes a cartridge, a cartridge support detachably connected to the cartridge, an actuating block including an unlocking component set movably in the cartridge, a cutter, and a lockout mechanism. The cutter is adapted to move longitudinally along the cartridge, between a first position and a second position. The mechanism includes a lockout block set in said cartridge support and transversely movable with respect to the support between third and fourth positions, and a flexible component set between the support and the lockout block and actuating the lockout block to move from the third to the fourth positions. When the flexible component is under compression, the cutter can move from the first to the second positions. After the actuating block is actuated, the lockout block moves to the fourth position under action of the flexible component.

Abstract: A staple cartridge includes outer and inner rows of retention slots that are adapted and configured to retain staples. The staple cartridge further includes a staple pusher including a plurality of pusher plates. A staple pusher includes pusher plates that are laterally spaced apart to engage staples within the outer rows of at least three rows of retention slots.

Abstract: A surgical stapling apparatus includes a handle, a tool assembly, and a staple cartridge. The handle includes an actuation trigger. The tool assembly is operatively coupled to the handle. In addition, the tool assembly includes a first jaw member and a second jaw member. The staple cartridge is releasably supported on the first jaw member. The staple cartridge includes first and second buttress materials and a spring member extending from the staple cartridge. The spring member is configured to support the second buttress material away from the first buttress material.

Abstract: This document relates to the apparatus and methods used in the minimally invasive creation of arteriovenous fistula (AVF). In particular, the invention relates to the creation of an AVF using catheters and an alignment methodology that is based upon detection of asymmetric electric fields. The invention finds particular application in vascular access (VA) in the hemodialysis (HD) population.

Abstract: The present disclosure describes the use of nerve conduits as scaffolds for nerve regeneration, including spinal cord regeneration. The conduit may be hollow or contain a luminal filler such as agar or other biocompatible material.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: Disclosed herein are detachment mechanisms for vaso-occlusive devices that allow for rapid operator-controlled release of the vaso-occlusive device into the selected site. Also disclosed are vaso-occlusive assemblies comprising these detachment mechanisms and methods of using these detachment mechanisms and vaso-occlusive assemblies.

Abstract: An intranasal occlusion device having an inflatable balloon within a sponge that is used to prevent drainage of fluid, such as blood and other fluids into the airway during sinus and nasal minor procedures or surgeries, and methods of using the device to occlude an intranasal cavity of a patient. The device provides for suction to remove the fluid and may facilitate office-based minor procedures or surgeries.

Abstract: A vessel occluder used to occlude blood flow within the vasculature is described. The vessel occluder can include an expandable mesh portion having a flexible membrane that expands within a cavity of the expandable mesh portion. When expanded, the flexible membrane blocks blood passage through the mesh portion.

Abstract: Tourniquet devices configured in accordance with several embodiments of the disclosure can include, for example, a strap having a proximal end portion and a distal end portion, a buckle assembly connected to the proximal end portion, and a pulley assembly movably coupled to the strap. Tourniquet devices configured in accordance with the technology can be easily applied because the pulley assemblies can reduce the force a user must exert on the tourniquet devices to constrict or occlude blood flow at a specific artery. Additionally, tourniquet devices disclosed herein can also serve as functional, wearable items (e.g., a belt, integrated into clothing) such that the tourniquet devices are conveniently stored and readily accessible in emergencies.

Abstract: Drill assemblies and methods for drilling into bone are provided. In general, a drill assembly can have a flexible distal portion configured to move between a substantially straight configuration, in which a longitudinal axis of the distal portion is aligned with a longitudinal axis of a proximal shaft portion of the drill assembly, and a curved configuration, in which the longitudinal axis of the distal portion is angularly offset from the longitudinal axis of the proximal shaft portion. The drill assembly can include a proximal shaft, a drill tip, and a plurality of segments located between the proximal shaft and the drill tip. The drill assembly can include a connecting element extending from the proximal shaft, through the segments, and to the drill tip at a distal end of the drill assembly. The drill assembly can include a conformal covering on the distal portion thereof that is configured to curve.

Abstract: A device is provided, including a cutting rib, the cutting rib including an arcuate portion having an outer sharp edge and a centralizer configured to receive the cutting rib through a radial slot, the radial slot forming a gap with the cutting rib. The arcuate portion of the cutting rib is formed into a profile that follows a surface of the centralizer, the outer sharp edge of the arcuate portion of the cutting rib has a wavy profile that forms a tunnel in the gap between the centralizer and the cutting rib, and the outer sharp edge of the arcuate portion of the cutting rib protrudes outwardly from the surface of the centralizer. A method for using the device to cut bone in a surgical configuration is also provided.

Abstract: A surgical measurement instrument for use in surgery is configured so that a measurement operation can be more readily performed using this surgical measurement instrument. The surgical measurement instrument has a laser application portion. The laser application portion is used in surgery to perform treatment on a tibia of a patient. The laser application portion can apply a laser beam to measure a positional relationship between the tibia and a knee joint center.