Patents Issued in December 21, 2017
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Publication number: 20170361090Abstract: GI tract treatment and monitoring devices configured for temporary implantation in the GI tract and non-invasive removal via natural body processes are disclosed. Methods of implantation, treatment and monitoring with disclosed devices are also disclosed. Devices include bio-active fixation that allows removal from the body by natural processes after a time that may be engineered in the fixation elements. In some embodiments, devices are configured to be implanted on GI tract tissue and transmurally migrate into the GI tract to be passed from the body. In other embodiments, devices are configured for placement within the GI tract via a delivery tube such as an NJ/NG tube. Embodiments include stimulation devices for treating conditions such as ileus and sensors for monitoring GI leaks and/or biological or chemical markers for various GI tract conditions.Type: ApplicationFiled: October 23, 2015Publication date: December 21, 2017Inventors: Hanson S. Gifford, III, Mark Deem
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Publication number: 20170361091Abstract: Provided herein are devices, systems, and methods for treating urological and gastrointestinal disorders, including bedwetting, through stimulation of the dorsal or plantar surface of the foot, including the superficial peroneal nerve and branches thereof, such as the dorsal intermediate and medial cutaneous nerves, or the medial and/or and lateral plantar nerves. The device facilitates placement of electrodes on the foot. Also provided herein is a system including the device, a pulse generator, and a controller, and methods of manufacturing and using the same.Type: ApplicationFiled: December 21, 2015Publication date: December 21, 2017Applicant: University of Pittsburgh - Of the Commonwealth System of Higher EducationInventor: Changfeng Tai
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Publication number: 20170361092Abstract: Systems and methods for the treatment of gastroesophageal reflux disease (GERD) include at least one electrically stimulating electrode coupled to a pulse generator. Individuals with GERD are treated by implanting a stimulation device within and/or proximate the patient's lower esophageal sphincter, gastric fundus, or other nearby gastrointestinal structures and applying electrical stimulation to the patient's lower esophageal sphincter and/or fundus, in accordance with certain predefined protocols. Electrical stimulation provided by the disclosed systems results in an increase in the length of the high pressure zone of the LES and/or modulation of the receptive relaxation response of the fundus to decrease gastric pressure, creating a longer barrier to the reflux of gastric contents or increasing functional lower esophageal pressure respectively, thereby treating GERD.Type: ApplicationFiled: June 30, 2017Publication date: December 21, 2017Inventors: Virender K. Sharma, Shai Policker
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Publication number: 20170361093Abstract: Nerve stimulation systems and methods are disclosed for providing modulation of nerve targets in the lower limbs typically at or below the knee. For example, transcutaneous electrical nerve stimulation (TENS), percutaneous nerve stimulation, and implantable stimulation systems and methods are disclosed for providing stimulation to the saphenous nerve (SAFN). Additionally, systems and methods are provided for co-stimulating the posterior tibial nerve (PTN) and SAFN in combination with unique stimulation, and with control and display of OAB therapy protocols for multiple sites. Systems and methods of treatment can provide for management of usage and compliance monitoring, obtain and operating upon patient input responses to queries and management of payments and permissions related to provision of therapies for various disorders. Monitoring of usage and compliance can be managed both locally and remotely from a user. Stimulation provided in combination with a passive implantable component is also disclosed.Type: ApplicationFiled: August 16, 2017Publication date: December 21, 2017Inventors: PAUL B. YOO, MICHAEL SASHA JOHN
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Publication number: 20170361094Abstract: An electrostimulation device comprises a hand-held electrostimulation generator receiving an input music signal and providing at an output a nerve electrostimulation signal modulated by the music signal, an electronic signal conduit having conductive leads conductively connected to the output of the electrostimulation generator, and an electrode coupler comprising an earbud.Type: ApplicationFiled: August 14, 2017Publication date: December 21, 2017Applicant: Nervana, LLCInventors: Richard Cartledge, Daniel Cartledge, Ami Brannon, Kermit Falk, Gregory L. Mayback
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Publication number: 20170361095Abstract: A disposable electrical stimulation device and method for providing therapeutic treatment and pain management in a convenient, compact configuration. Electrode size and shape and relative configuration can be varied according to an intended application and use, or a universal configuration can be provided for use on almost any area of the body. The common structure of communicatively coupled dual electrodes including control circuitry and a power source accommodates a range of different sizes, configurations, stimulation treatment intensities, and other physical and electrical characteristics that can be pre-customized and packaged for specific, limited time use. The device can therefore be used in methods of providing therapy, managing pain, and achieving other treatment goals by electrical stimulation.Type: ApplicationFiled: June 1, 2017Publication date: December 21, 2017Inventors: Pierre-Yves Mueller, Marshall Masko, Pierre-Yves Lampo, Klaus Schonenberger, Felix Buhlmann, Steve Guex, Gary L. Moore, Patrick Lavalley
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Publication number: 20170361096Abstract: A method for providing electrical stimulation to a user, the method comprising: providing an electrical stimulation device, in communication with a controller, at a head region of the user; with the electrical stimulation device, providing a stimulation treatment having a waveform configured for neuromodulation in the user; with the controller, performing an adjustment to the stimulation treatment, wherein performing the adjustment includes: generating a transformed waveform with application of a transfer function to the waveform, wherein the transfer function scales the waveform and selectively attenuates extreme waveform values while maintaining a frequency characteristic of the waveform in the transformed waveform; and applying the transformed waveform with the electrical stimulation device, thereby modulating the stimulation treatment.Type: ApplicationFiled: September 5, 2017Publication date: December 21, 2017Inventor: Brett Wingeier
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Publication number: 20170361097Abstract: Respiratory sinus arrhythmia, or another bodily function that indicates a patient's parasympathetic tone, is used to control the delivery of vagal nerve stimulation to the patient for treating disorders that can be reflected and influenced by the behavior of the autonomic nervous system.Type: ApplicationFiled: December 14, 2015Publication date: December 21, 2017Applicant: Unversity of Florida Research Foundation, Inc.Inventors: John Bonar WILLIAMSON, Damon Geoffrey LAMB, Eric S. Carter PORGES
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Publication number: 20170361098Abstract: A signal processing method for cochlear implant is performed by a speech processor and comprises a noise reduction stage and a signal compression stage. The noise reduction stage can efficiently reduce noise in a electrical speech signal of a normal speech. The signal compression stage can perform good signal compression to enhance signals to stimulate cochlear nerves of a patient with hearing loss. The patient who uses a cochlear implant performing the signal processing method of the present disclosure can accurately hear normal speech.Type: ApplicationFiled: August 31, 2017Publication date: December 21, 2017Inventor: KUN-HSI TSAI
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Publication number: 20170361099Abstract: The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a combination of burst and tonic stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder.Type: ApplicationFiled: May 22, 2017Publication date: December 21, 2017Inventor: Dirk De Ridder
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Publication number: 20170361100Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for extravascular delivery of pulsed electric fields to achieve such neuromodulation.Type: ApplicationFiled: June 28, 2017Publication date: December 21, 2017Inventors: Mark Deem, Denise Zarins, Douglas Sutton, Hanson Gifford, III, Howard R. Levin, Mark Gelfand, Benjamin J. Clark
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Publication number: 20170361101Abstract: A method of controlling a neural stimulus by use of feedback. The neural stimulus is applied to a neural pathway in order to give rise to an evoked action potential on the neural pathway. The stimulus is defined by at least one stimulus parameter. A neural compound action potential response evoked by the stimulus is measured. From the measured evoked response a feedback variable is derived. A feedback loop is completed by using the feedback variable to control the at least one stimulus parameter value. The feedback loop adaptively compensates for changes in a gain of the feedback loop caused by electrode movement relative to the neural pathway.Type: ApplicationFiled: December 11, 2015Publication date: December 21, 2017Applicant: Saluda Medical Pty LtdInventor: Peter Scott Vallack Single
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Publication number: 20170361102Abstract: A method and system for treating cardiac arrhythmias which includes inserting one or more electrodes into a patient's neck, and connecting the electrodes to the vagus nerve in the patient's neck. A cardiac monitoring device detects a cardiac arrhythmia. A controller connected to an electrical power source provides electrical power to the electrodes to apply electrical stimulation to the vagus nerve when a cardiac arrhythmia is detected.Type: ApplicationFiled: June 30, 2017Publication date: December 21, 2017Applicant: The Research Foundation for The State University of New YorkInventors: Mark Stewart, Isaac Naggar, Jason Lazar
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Publication number: 20170361103Abstract: A system and method are provided to deliver interleaved stimulation to nerve tissue of interest. The system and method comprises an array of stimulation electrodes. The array is configured to be implanted proximate to nerve tissue of interest. An implantable medical device (IMD) is coupled to the array. The IMD includes memory storing a composite resultant pulse (CRP) sequence comprising first and second component sequences of first and second resultant pulse trains, respectively. One or more pulses from at least one of the first or second component sequences are temporally shifted relative to a corresponding target component sequence. The IMD further comprises a pulse generating circuit and switching circuit coupled to an output of the pulse generating circuit and the array. The switching circuit is configured to connect the pulse generating circuit to different combinations of the electrodes.Type: ApplicationFiled: June 15, 2016Publication date: December 21, 2017Inventor: Banko I. Hadjiyski
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Publication number: 20170361104Abstract: An example of a system for delivering neurostimulation pulses to a patient using a plurality of electrodes and controlling the delivery of the neurostimulation pulses by a user may include a programming control circuit and a user interface. The programming control circuit may be configured to generate a plurality of stimulation parameters controlling delivery of neurostimulation pulses according to one or more stimulation waveforms. The interface may include a display screen and an interface control circuit. The interface control circuit may be configured to define the one or more stimulation waveforms, and may include an impedance presentation module. The impedance presentation module may be configured to determine values of impedances each between two electrodes of the plurality of electrodes for all of combinations of two electrodes available from the plurality of electrodes and display the determined values of impedances on the display screen.Type: ApplicationFiled: August 30, 2017Publication date: December 21, 2017Inventors: Stephen Carcieri, Michael A. Moffitt, Peter J. Yoo, Dennis Allen Vansickle, Sridhar Kothandaraman, Michael Andrew Caruso, Dean Chen
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Publication number: 20170361105Abstract: The present disclosure provides systems and methods for combining tonic deep brain stimulation (DBS) and random DBS. A system includes a stimulation lead including a plurality of contacts, and an implantable pulse generator (IPG) communicatively coupled to the stimulation lead and configured to cause tonic stimulation to be delivered using one contact of the plurality of contacts, and cause random stimulation to be delivered using a subset of the remaining contacts of the plurality of contacts.Type: ApplicationFiled: June 15, 2016Publication date: December 21, 2017Inventors: Filippo Agnesi, Lalit Venkatesan
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Publication number: 20170361106Abstract: Systems and methods are provided for reducing stimulation interference between two stimulation modules positioned on a user's body, which may be used in stimulation systems without a central treatment controller. Systems and methods are also provided for stimulation treatment using multiple independent stimulators wirelessly managed by a remote management device.Type: ApplicationFiled: June 2, 2017Publication date: December 21, 2017Inventors: NICOLAS FONTAINE, STEVE GUEX, FLAVIEN BAUMGARTNER
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Publication number: 20170361107Abstract: Computer implemented methods and systems are provided for automatically determining capture thresholds for an implantable medical device equipped for cardiac stimulus pacing using a multi-pole left ventricular (LV) lead. The methods and systems measures a base capture threshold for a base pacing vector utilizing stimulation pulses varied over at least a portion of an outer test range. The base pacing vector is defined by a first LV electrode provided on the LV lead and a second electrode located remote from an LV chamber. The methods and systems designate a secondary pacing vector that includes the first LV electrode and a neighbor LV electrode provided on the LV lead. The methods and systems further define an inner test range having secondary limits based on the base capture threshold, wherein at least one of the limits for the inner test range differs from a corresponding limit for the outer test range.Type: ApplicationFiled: March 10, 2016Publication date: December 21, 2017Inventors: Luke C. McSpadden, Fujian QU, Cyrille S. Casset, Chunlan Jiang, Kyungmoo Ryu, Caroline Jordan, Yelena Nabutovsky, Nima Badie
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Publication number: 20170361108Abstract: A connector assembly includes a receptacle body that defines a portion of a connector lumen and further includes connector contacts disposed within the receptacle body along the connector lumen. The connector assembly further includes a rotational member that defines another portion of the connector lumen and includes a head portion and an elongated portion. The elongated portion defines an inner surface and an outer surface. The outer surface is rotatably coupled to the receptacle body. Fastener threading is disposed along at least a portion of the inner surface of the elongated portion. The receptacle body and rotational member are configured and arranged to receive a portion of a lead or a lead extension in the connector lumen.Type: ApplicationFiled: June 19, 2017Publication date: December 21, 2017Inventor: Jacob B. Leven
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Publication number: 20170361109Abstract: There is disclosed an apparatus for treating a sexual dysfunctional female patient, comprising an implanted stimulation device adapted to stimulate at least a part of the vagina of the patient by movement of said stimulation device and contact between said stimulation device and the sexually responsive tissue or the wall of the vagina. A system and an operation method for the treatment of female sexual dysfunction are also disclosed.Type: ApplicationFiled: April 24, 2017Publication date: December 21, 2017Inventor: Peter Forsell
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Publication number: 20170361110Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed. The charging system features an electronics module connected to a charging coil by a cable. The charging system can be configured with a belt or harness that holds the charging coil position to charge the IMD and also providing a user with easy access to the electronics module. Resistance in the cable between electronics module and the charging coil is minimized by using multiple, individually insulated conductors to carry AC current.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventor: Thomas W. Stouffer
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Publication number: 20170361111Abstract: A charging system for an Implantable Medical Device (IMD) includes a split charging coil for generating a magnetic field to provide power to the IMD. The split charging coil includes a first coil portion and a second coil portion, each of which can be formed as a mechanical winding of an insulated conductor. The first and second coil portions are connected to each other in a way that substantially reduces or eliminates any current-carrying path that is routed radially with respect to the coil. As a result, the split coil produces a uniform magnetic field that enables a more accurate determination of alignment between the coil and the IMD than is available using traditional charging coils.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventor: Thomas W. Stouffer
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Publication number: 20170361112Abstract: An external charger for an implantable medical device (IMD) includes a multi-layer shield to direct the magnetic field generated by its charging coil towards the IMD. Each of the shield's multiple layers includes a ferromagnetic material that increases the permeance of the magnetic field's flux paths. The layers decrease in magnetic saturation point with increasing distance from the external charger's charging coil. That is, the layer closest to the charging coil has a higher saturation point than the next layer further from the charging coil, and so on. Layers that are positioned closer to the charging coil shield layers that are further from the charging coil, which generally have higher magnetic permeabilities, such that the magnetic intensity does not exceed any layer's saturation point. In this way, the multi-layer shield provides a beneficial balance between permeability and saturation, which can limit the required dimensions of the shield.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventor: Thomas W. Stouffer
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Publication number: 20170361113Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils. The charging coil and one or more sense coils are preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the one or more sense coils are concentric with the charging coil and preferably formed in one or more traces of a circuit board. The magnitude of one or more voltages induced on the one or more sense coils can be measured to determine the position of the charging coil relative to the IMD, and in particular whether the charging coil is (i) centered, (ii) not centered but not misaligned, or (iii) misaligned, with respect to the IMD being charged, which three conditions sequentially comprise lower coupling between the charging coil and the IMD.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventors: Daniel Aghassian, Thomas W. Stouffer
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Publication number: 20170361114Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils. The charging coil and one or more sense coils are preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the one or more sense coils are concentric with the charging coil and preferably formed in one or more traces of a circuit board. One or more voltages induced on the one or more sense coils can be used to determine whether the charging coil is (i) centered, (ii) not centered but not misaligned, or (iii) misaligned, with respect to the IMD being charged, which three conditions sequentially comprise lower coupling between the charging coil and the IMD. A charging algorithm is also disclosed that control charging dependent on these conditions.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventors: Daniel Aghassian, Thomas W. Stouffer
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Publication number: 20170361115Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils. The charging coil and one or more sense coils are preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the one or more sense coils are concentric with the charging coil and preferably formed in one or more traces of a circuit board. One or more voltages induced on the one or more sense coils can be used to determine the resonant frequency of the charging coil/IMD coupled system. The determined resonant frequency can then be used to determine the position of the charging coil relative to the IMD. The magnetic field produced from the charging coil may also be driven at the resonant frequency to optimize power transfer to the IMD.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventors: Daniel Aghassian, Thomas W. Stouffer, Lev Freidin
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Publication number: 20170361116Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the sense coils are preferably formed in one or more traces of a circuit board. One or more voltages induced on the one or more sense coils can be used to determine one or more parameters (magnitude, phase angle, resonant frequency) indicative of the position between the charging coil and the IMD, which position may include the radial offset and possibly also the depth of the charging coil relative to the IMD. Knowing the position, the power of the magnetic field produced by the charging coil can be adjusted to compensate for the position.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventors: Daniel Aghassian, Thomas W. Stouffer, Jonathan Larcom, Gaurav Gupta
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Publication number: 20170361117Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the sense coils are preferably formed in one or more traces of a circuit board. One or more voltages induced on the one or more sense coils can be used to determine a phase angle between the voltage and a driving signal for the charging coil. The determined phase angle can then be used to determine the position of the charging coil relative to the IMD. Additionally, more than one parameter (phase angle, magnitude, resonant frequency) may be determined using the voltage may be used to determine position, including the radial offset and depth of the charging coil relative to the IMD.Type: ApplicationFiled: June 7, 2017Publication date: December 21, 2017Inventors: Daniel Aghassian, Thomas W. Stouffer, Jonathan Larcom, Gaurav Gupta
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Publication number: 20170361118Abstract: A defibrillator (AED) using two different ECG analysis algorithms which work sequentially to improve the accuracy of AED shock decisions. A first algorithm, such as (ART), is particularly suited for analysis in the presence of CPR periods. A second algorithm, such as (PAS), is particularly suited for analysis during hands-off periods. The AED switches algorithms depending on the period and on the current analysis of the cardiac rhythm. The inventions thus provide an optimized ECG analysis scheme in a manner that improves the effectiveness of the rescue, resulting in more CPR “hands-on” time, better treatment of refibrillation, and reduced transition times between CPR and electrotherapy.Type: ApplicationFiled: December 9, 2015Publication date: December 21, 2017Inventors: CHENGUANG LIU, STACY EARL GEHMAN, JAMES KNOX RUSSELL, CHRISTOPHER WILLIAM FLEMING, DAWN BLILIE JORGENSON, DAVID ROY AXNESS, JEFFREY MARTIN BOSCHEE
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Publication number: 20170361119Abstract: A defibrillator (AED) and method for using a defibrillator incorporates a user activated button which truncates an ongoing ECG analysis to immediately perform a different defibrillator-related function. For example, the AED may use two different ECG analysis algorithms having different sensitivities to a shockable cardiac rhythm, and a press of the button may automatically shift from a first algorithm to a second algorithm with the higher sensitivity. The button may also allow truncation of ongoing analysis and CPR for immediate preparation for electrotherapy.Type: ApplicationFiled: December 9, 2015Publication date: December 21, 2017Inventors: STACY EARL GEHMAN, JEFFREY MARTIN BOSCHEE, CHRISTIAN JAMES RICHARD
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Publication number: 20170361120Abstract: A defibrillator and method for using a defibrillator which adopts an ECG analysis algorithm that can detect a cardiac arrhythmia in the presence of noise artifact induced by cardio pulmonary resuscitation (CPR) compressions. The apparatus and method includes a confidence analyzer circuit which determines the confidence level of an electrotherapy shock decision based on the detection. If the confidence level is low, the apparatus adjusts its shock decision criteria.Type: ApplicationFiled: December 9, 2015Publication date: December 21, 2017Inventors: CHENGUANG LIU, STACY EARL GEHMAN, DAWN BLILIE JORGENSON
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Publication number: 20170361121Abstract: A defibrillator and method for using a defibrillator which adopts an ECG analysis algorithm that can detect a cardiac arrhythmia in the presence of noise artifact induced by cardio pulmonary resuscitation (CPR) compressions. The apparatus and method provides both of a continuous and scheduled mode of operation for interleaving periods of CPR with electrotherapy, in a manner that improves the effectiveness of the rescue, resulting in more CPR “hands-on” time, better treatment of refibrillation, and reduced transition times between CPR and electrotherapy.Type: ApplicationFiled: December 9, 2015Publication date: December 21, 2017Inventors: CHENGUANG LIU, STACY EARL GEHMAN, JAMES KNOX RUSSELL, CHRISTOPHER WILLIAM FLEMING, DAWN BLILIE JORGENSON, DAVID ROY AXNESS, JEFFREY MARTIN BOSCHEE
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Publication number: 20170361122Abstract: An implantable device for optically stimulating a brain of a human being or animal, including: a multi-channel biocompatible catheter including a plurality of channels extending substantially parallel to each other relative to a longitudinal axis of the multi-channel catheter; a light guide, extending into one channel, for optically stimulating the brain, the multi-channel catheter acting as a sheath totally enveloping the light guide; a functional element, extending into another channel, to measure light injected into a surrounding medium at a distal end of the light guide and/or an element acting on the shape of the multi-channel catheter.Type: ApplicationFiled: December 18, 2015Publication date: December 21, 2017Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Claude CHABROL, Alim-Louis BENABID
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Publication number: 20170361123Abstract: An apparatus for treatment of fungal infections and/or other foot skin disorders, comprises a shoe-type housing having a substantially hollow interior forming a treatment chamber, a supporting platform disposed within the hollow chamber; so that a foot of a patient positioned within the treatment chamber is supported by the platform, so that nails are disposed at the lower level of the front part of the chamber, whereas the heel of the foot is being elevated a rear part thereof. A delivery and control assembly for the aqueous solution is provided. At least one light delivery arrangement is disposed within or in the vicinity of the treatment chamber.Type: ApplicationFiled: June 28, 2017Publication date: December 21, 2017Inventor: Pavel V. Efremkin
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Publication number: 20170361124Abstract: A method for treating an eye condition of a user using at least one light source, the at least one light source having an output which is adjustable in at least one of spectrum shape, intensity, or duration, the method comprising: (a) obtaining information relating to an eye condition of the user; (b) determining a dose of light to treat the eye condition, the dose including one or more of a particular spectrum shape, a particular intensity, or a particular duration; and (c) causing the at least one light source to adjust the output to deliver the dose.Type: ApplicationFiled: December 19, 2016Publication date: December 21, 2017Inventors: JEFFERY ROBERT PARKER, AURELIEN J.F. DAVID
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Publication number: 20170361125Abstract: A tanning or a phototherapy system including a light source including light emitting elements configured to emit ultraviolet (UV) light having different peak wavelengths, a controller configured to control luminous characteristics of the light source, and a sensor configured to sense at least one of the luminous characteristics of the light source and a user's skin condition, in which the luminous characteristics of the light source are controlled by the controller based on the user's skin condition sensed by the sensor, and controlling the luminous characteristics comprises increasing or decreasing luminous intensity of one or more of the light emitting elements.Type: ApplicationFiled: June 20, 2016Publication date: December 21, 2017Inventors: Emmanuel Lakios, Max Shatalov, Timothy Bettles, Alex Dobrinsky
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Publication number: 20170361126Abstract: Nanoparticle mediated microvascular embolization (NME) of tumor tissue may occur after systemic administration of PEM, leading to widespread shutdown of vascular flow, hemorrhage, and necrosis. PEM constructs are developed that incorporate large amounts of iron-containing protein, possess high oxygen affinities, and demonstrate delayed nitric oxide binding. Such properties induce selective NME of tumors after extravasation, and will likely enhance the effect of VEGFR TKIs and/or mTOR inhibitors.Type: ApplicationFiled: August 6, 2015Publication date: December 21, 2017Inventor: P. Peter GHOROGHCHIAN
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Publication number: 20170361127Abstract: A method and related system to adjust an existing treatment plan. A second optimization is run based on a dual objective function system that includes a first objective function used for the optimization in respect of the existing plan and a second, extended objective function that includes the said first objective function as a functional component.Type: ApplicationFiled: December 4, 2015Publication date: December 21, 2017Inventors: Vaitheeswaran RANGANATHAN, Gipson JOE ANTO, Prashant KUMAR
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Publication number: 20170361128Abstract: Apparatus and techniques are described herein for nuclear magnetic resonance (MR) projection imaging. Such projection imaging may be used to control radiation therapy delivery to a subject, such as including receiving reference imaging information, generating a two-dimensional (2D) projection image using imaging information obtained via nuclear magnetic resonance (MR) imaging, the 2D projection image corresponding to a specified projection direction, the specified projection direction including a path traversing at least a portion of an imaging subject, determining a change between the generated 2D projection image and the reference imaging information, and controlling delivery of the radiation therapy at least in part using the determined change between the obtained 2D projection image and the reference imaging information.Type: ApplicationFiled: December 10, 2015Publication date: December 21, 2017Inventors: Martin Emile LACHAINE, Tony FALCO
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Publication number: 20170361129Abstract: Disclosed herein is an agent for shaping or altering the shape of hair, such as by straightening or relaxing hair, the agent comprising: A. a hair treatment composition containing an alkaline material selected from a hydroxide-containing compound and a carbonate compound; a cationic polymer selected from a quaternary diammonium polycondensate; an amphoteric polymer selected from a quaternary ammonium compound; an organic solvent, and water; and optionally, B. an activator component; wherein the pH of the composition is equal to or greater than 12 and wherein the weight ratio of (b) to (c) ranges from about 1 up to about 3.Type: ApplicationFiled: December 17, 2015Publication date: December 21, 2017Applicant: L'OREALInventors: Angela ELLINGTON, Eric OSEI-ACQUAH, Frederic CERVANTES
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Publication number: 20170361130Abstract: The invention relates to a novel stabilized and solubilized topical formulation for cosmetic improvements and methods of making the same comprising multiplexed molecular penetration enhancers and essential and semi-essential amino acid protein binders for the topical application and transdermal delivery of one or more active ingredients and/or pharmaceutical agents. The invention further relates to the use of the topical formulation in connection with the providing of cosmetic improvements in individuals.Type: ApplicationFiled: December 10, 2013Publication date: December 21, 2017Inventor: PANKAJ MODI
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Publication number: 20170361131Abstract: The invention relates to a polysaccharide polymer of formula (I): PS—(O—CO-L-X)a(OH)b ??(I) in which PS denotes the basic backbone of the polysaccharide bearing the hydroxyl groups; L is a divalent hydrocarbon-based group comprising from 1 to 20 carbon atoms; X denotes a photoactive group of azide or diazirine type; a denotes the content of OH groups substituted with the photoactive group; b denotes the content of unsubstituted free OH groups; a being between 0.02 and 0.5; b being between 0.5 and 0.98; and a+b=1. The invention also relates to a composition comprising the polymer (I) in a physiologically acceptable medium, and also to a cosmetic process for caring for the skin, comprising the topical application to the skin of said composition and exposure of the treated skin to light radiation.Type: ApplicationFiled: November 30, 2015Publication date: December 21, 2017Inventor: Andrew Greaves
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Publication number: 20170361132Abstract: An electronic directional indicator includes a microcontroller in electronic communication with an electronic compass, an electronic motion-detecting module and at least one light source that is controllably illuminable. A battery life of the electronic directional indicator is managed by monitoring the electronic motion-detecting module for motion within pre-defined time periods and reducing power to electronic components accordingly. The electronic directional indicator can be placed on the face shield portion of a self-contained breathing apparatus face mask to provide a constant source of orientation for fire-fighters in reduced- or zero-visibility environments.Type: ApplicationFiled: December 7, 2015Publication date: December 21, 2017Inventor: Jeffrey L. Dykes
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Publication number: 20170361133Abstract: A personal entertainment respiratory apparatus provides air to a user to provide a fully immersive entertainment experience. The personal entertainment system may comprise a flow generator for providing the flow of air. A personal spatial respiratory interface may be coupled to the flow generator. The personal spatial respiratory interface may comprise an outlet for the flow generator. The personal spatial respiratory interface may further be configured to direct the flow of air within an ambient breathing proximity of a user. The personal entertainment respiratory apparatus may further comprise a controller and a sensory particle dispenser. The controller and sensory particle dispenser may be configured to selectively activate release of a sensory particle from the dispenser into the directed flow of air in response to an entertainment triggering signal.Type: ApplicationFiled: December 4, 2015Publication date: December 21, 2017Applicant: ResMed LimitedInventors: Tzu-chin Yu, Emma Anne Connell, David Creusot, Donald Darkin, Barton John Kenyon, Paul Jan Klasek, Andrew Sims, Quangang Yang, Philip Rodney Kwok
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Publication number: 20170361134Abstract: A breathing apparatus including a face mask adapted to substantially cover a face of a user and a neck component attached to the face mask and surrounding the user's neck. The face mask has a peripheral region which forms a pneumatic seal against the face and an air inlet arranged proximal to the peripheral region. The neck component houses a flow generator configured to receive unfiltered air from outside of the breathing apparatus, filter the unfiltered air, and convey the filtered air to the face mask through the air inlet.Type: ApplicationFiled: January 14, 2016Publication date: December 21, 2017Inventors: Alexander VIRR, Xiaoyi FU, Dan KAO, John Michael SNOW, Damian Charles JOHNSON
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Publication number: 20170361135Abstract: A roof truss anchor clamp for use with a worker's safety harness, a safety system incorporating the anchor clamp and a method of using the same. The anchor clamp includes a middle wall positionable adjacent an upper surface of a section of a roof truss rafter; a first side wall extending outwardly from one end of the middle wall; a second side wall extending outwardly from an opposite end of the middle wall; wherein a space is defined between the first and second side walls and the section of the rafter is receivable in the space. A fastener assembly is provided on the anchor clamp for securing the clamp to the rafter. A connector is also engaged with the anchor clamp for securing a worker's safety harness thereto.Type: ApplicationFiled: June 20, 2017Publication date: December 21, 2017Inventor: Lawrence A. Crookston
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Publication number: 20170361136Abstract: An ant-falling device includes a shell, a first axle and a second axle supported therein, a buffer unit coupled at the first axle, and a reel spring for retracting the buffer unit. The buffer unit includes a rope reel and a driven gear. The second axle includes a driving gear, a first buckling member, and a handle that controls the driving gear to engage with the driven gear for retracting a rope via the rope reel. The shell includes a button, having a second buckling member, movably mounted thereon and being pushed by a spring. When the driving gear is engaged with the driven gear, the button is actuated to couple the second buckling member with the first buckling member to enable the rope being smoothly retracted. As the button is pressed, the first buckling member is released to disengage the driving gear with the driven gear.Type: ApplicationFiled: June 17, 2016Publication date: December 21, 2017Inventor: Fang-Kuan Wu
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Publication number: 20170361137Abstract: A self-braking pulley is disclosed for controlling a rate of extraction of a tether coupled with the pulley. The pulley comprises a pulley housing, a spool for receiving a tether, the spool being configured to rotate about a first axis, relative to the pulley housing, and a piston assembly comprising a chamber having a first and second chamber portion which are rotationally locked to the housing. The piston assembly further comprises a fluid disposed within the chamber, a piston which is arranged to move within the chamber along a second axis between the first and second chamber portions and at least one bore formed within the piston for fluidly coupling the first and second chamber portions. The pulley further comprises means for coupling rotational motion of the spool with reciprocating motion of the piston back and forth between the chamber portions, to cause the fluid to transfer between the chamber portions via the at least one bore as the spool rotates.Type: ApplicationFiled: June 20, 2017Publication date: December 21, 2017Inventor: Stephen GRIFFITHS
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Publication number: 20170361138Abstract: A method is described for using cellular glass blocks, cellular glass nodules, hollow glass spheres, or other buoyant glass materials to attenuate oil fire, limit thermal radiation from an oil fire, and reduce the risk of boil-over phenomenon. Cellular glass blocks, cellular glass nodules, hollow glass spheres, or other buoyant glass products may be deployed passively, prior to an ignition event, or actively, as a response to an ignition event to provide control. Cellular glass or other buoyant glass materials may be in any physical shape such as block, sheet, aggregate, or nodule.Type: ApplicationFiled: August 31, 2017Publication date: December 21, 2017Applicant: PITTSBURGH CORNING CORPORATIONInventors: Brandon Alan Stambaugh, Steven Robert Badger
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Publication number: 20170361139Abstract: An enclosure, vehicle, and method for containing an overheating device are provided. An enclosure includes a body and a door that form a volume. The body includes is connected to a Venturi tube that is in communication with a fluid flow path flowing across an opening at an opposite end. In the event an overheating device is placed in the enclosure, a pressure sensor measures a pressure in the volume and a controller opens a first valve in a flow path through the Venturi tube so that air is pumped from the volume via the Venturi effect. The first valve is closed when the measured pressure drops below a threshold pressure. The enclosure can also include an extinguishing agent that can be expelled into the volume if a temperature sensor measures a temperature above a threshold temperature.Type: ApplicationFiled: June 17, 2016Publication date: December 21, 2017Inventors: Rocke R. KOREIS, Joseph A. SCARCE