Abstract: The present invention provides an anti-HPV E7 protein monoclonal antibody and the use thereof. The antibody can detect the HPV16 E7 protein with high specificity and recognize the HPV18 E7 protein, thereby it can distinguish between the cancerous cervical epithelial cells and the cervical abnormal or non-cancerous cervical epithelial cells.

Abstract: The invention relates to a novel antibody which binds to C-SLPI selected from the group consisting of SEQ ID NOs: 3 and 4.

Abstract: The present invention relates to a method of selecting individualized brain cancer therapy on the basis of the patient's PME-1 expression level in the diseased tissue.

Abstract: This document provides methods and materials for treating patients following an assessment of immune subtypes such as an assessment of peripheral blood phenotypes. For example, methods and materials for treating a mammal having a medical condition after assessing a mammal's level of CD14+/DR? cells (e.g., CD14+/DR? monocytes) and level of CD4+ cells (e.g., CD4+ T cells) and classifying the mammal has being likely to experience a favorable or unfavorable medical outcome based at least in part on the mammal's level of CD14+/DR? cells and level of CD4+ cells are provided.

Abstract: The invention relates methods of identifying and predicting inter-patient differences in prognostic prediction for survival in androgen independent prostate cancer. It further related to methods for determining and exploiting such differences to improve medical outcomes. Moreover, it provides methods for determining if a subject has prostate cancer.

Abstract: Methods of isolating, enriching, capturing, identifying, or detecting the presence of, cancerous cells in a sample, e.g., a blood sample from a subject, by detecting the presence of one or more cancer cell surface markers selected from the group consisting of cadherin 1 (CDH1), CDH2, CDH3, CDH4, CDH5, CDH9, CDH11, CDH17, CDH19, protocadherin 9 (PCDH9) and/or PCDH beta 13 (PCDHb13), and optionally an additional cancer cell surface marker, e.g., EpCAM, MUC1, EphB4, EGFR, CEA, and/or HER2.

Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

Abstract: The present invention relates to a method for a method for predicting the development of renal dysfunction in a subject following physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of: —a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject after physical trauma, after a hypotensive event, after sepsis, and/or after septic shock syndrome; b. predicting the development in the subject of renal dysfunction on the basis of the level of an anti-inflammatory cytokine determined in step a).

Abstract: The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations. In particular the invention provides millisecond-timescale temporal control of cation channels using moderate light intensities in cells, cell lines, transgenic animals, and humans. The invention provides for optically generating electrical spikes in nerve cells and other excitable cells useful for driving neuronal networks, drug screening, and therapy.

Abstract: A control unit outputs measurement status information including the time up to the completion of creation of the calibration curve for each of the desired measurement items to a display unit. The output/display of the calibration curve data measurement status for each of the items enables the operator to be aware of information about a failure to set a standard solution or to request the setting of the standard solution and to recognize how long he or she will need to wait until the creation of the calibration curve begins. The operator can therefore know what can be done while waiting, thereby improving job efficiency.

Abstract: An automatic biochemical analyzer, comprises a reaction wheel comprising an inner ring and an outer ring, wherein the reaction wheel is equally divided into multiple cuvette positions; the inner ring and the outer ring have a photoelectric detection position, a sample injecting position, a reagent injecting position, a sample stirring position, a reagent stirring position and a cuvette cleaning position; the photoelectric detection position of the inner ring is offset relative to that of the outer ring by a first cuvette position along a counterclockwise or clockwise direction; and the sample injecting positions, the reagent injecting positions, the sample stirring positions, and the reagent stirring positions of the inner ring are offset relative to those of the outer ring by a second cuvette position along the same direction, the first cuvette position is equal to the second cuvette position, or a difference between those two is one cuvette position.

Abstract: A laboratory sample distribution system comprising a transport plane and a cleaning device for cleaning the transport plane is presented. The cleaning device is adapted to automatically clean the transport plane similar to sample container carriers moving also on the transport plane. A laboratory automation system comprising such a laboratory sample distribution system is also presented.

Abstract: In determining whether a rack inputted to the automatic analyzer by the user is to be transferred to an analysis section or not, samples existing in a route from a buffer to a sample dispensing position in the analysis section are identified, and the number of items in which suction by a nozzle has not been completed in analysis items requested for the samples is managed. When the number of items is reduced to be smaller than a given number, the conveyance of a next rack from the buffer to the analysis section is controlled, thereby limiting the number of analysis items requested for samples in a waiting state for analysis in the analysis section constantly to be smaller than a fixed number. As a result, a period of time until a measurement result of emergency samples is outputted can be reduced even when emergency samples are newly inputted.

Abstract: According to an embodiment, a sample processing apparatus includes a detection section configured to detect pose information regarding a sample container which is configured to house a sample; and a raising section which turns the sample container in a predetermined direction based on the pose information regarding the sample container to raise the sample container.

Abstract: A sample-processing system that improves total system processing efficiency, and reduces a sample-processing time, by establishing a functionally independent relationship between a rack conveyance block with rack supply, conveyance, and recovery functions, and a processing block with sample preprocessing, analysis, and other functions. A buffer unit with random accessibility to multiple racks standing by for processing is combined with each of multiple processing units to form a pair, and the system is constructed to load and unload racks into and from the buffer unit through the rack conveyance block so that one unprocessed rack is loaded into the buffer unit and then upon completion of process steps up to automatic retesting, unloaded from the buffer unit. Functional dependence between any processing unit and a conveyance unit is thus eliminated.

Abstract: An automated instrument for processing a sample includes a first lock configured to move between a locked configuration and an unlocked configuration. The first lock is configured to be engaged with a first movable holding structure in the locked configuration to secure the first holding structure within the automated instrument. The first lock is configured to be disengaged from the first holding structure in the unlocked configuration to allow movement of the first holding structure within the automated instrument. The automated instrument also includes a robotic arm movable within the automated instrument and configured to move the first lock between the locked configuration and the unlocked configuration. The first holding structure is configured to hold a sample processing device and configured to move within the automated instrument when the first lock is in the unlocked configuration. The robotic arm can also be configured to move the sample processing device within the system.

Abstract: The invention relates to a pipetting apparatus for an automatic analysis device, which is particularly stable and allows simple and error-proof replacement of the pipetting apparatus and, therefore, particularly reliable operation of the analysis device. To this end, an essentially frustoconical fastening body is arranged around an axial region of the needle body.

Abstract: A rough road determination device (100) is mounted on a vehicle (1) that is equipped with an internal combustion engine (10) having a crank angle sensor (31). This rough road determination device is equipped with determination means (20) for determining whether or not a road on which the vehicle travels is a rough road, by comparing a first amplitude fluctuation amount as an amplitude fluctuation amount of one pulse of an output of the crank angle sensor, which is determined in advance on the basis of a rotational speed of the internal combustion engine, with a second amplitude fluctuation amount as an amplitude fluctuation amount of one pulse that is actually output from the crank angle sensor.

Abstract: A method for magnetic ranging includes rotating a downhole tool in a drilling well in sensory range of magnetic flux emanating from a target well. The downhole tool includes a magnetometer set and an accelerometer set rotatably coupled to the tool. The magnetometer set and the accelerometer set acquire corresponding magnetometer measurements and accelerometer measurements while rotating. The magnetometer measurements are transformed to a rotation independent reference frame to obtain rotation invariant measurements which are in turn processed to compute at least one of a distance and a direction from the drilling well to the target well.

Abstract: The invention relates to a micro-electromechanical device used as a force sensor, comprising a mobile mass connected to at least one securing zone by means of springs or deformable elements, and means for detecting the movement of the mobile mass, the mobile mass having an outer frame and an inner body, the outer frame and the inner body being connected by at least two flexible portions forming integral decoupling springs on two separate sides of the outer frame.

Abstract: The present invention relates to a spring contact, which is integrally formed by blanking and bending a metal plate member, the spring contact comprising: an upper head portion 32 having an upper tip 31 protruding upward; a spring portion (36) formed by a strip cylindrically bent, the strip extending in a zigzag pattern from an upper connection portion 35 extending downward from the upper head portion 32; a lower head portion 39 extending downward from a lower connection 37 extending from the lower end of the spring portion 36; and a lower tip 40 being provided on the lower end of the lower head portion 39. The present invention is advantageously suitable for manufacturing a fine-pitch spring contact and can improve productivity and reduce manufacturing costs.

Abstract: In one embodiment of the present invention, a test probe assembly for testing packaged integrated circuit (IC) devices includes a plurality of probes, a pad and a PCB/interposer. The plurality of probes is configured to repeatedly maintain reliable electrical contact with a corresponding plurality of DUT contacts when under a compliant force. The pad provides mechanical support and/or electric coupling for the plurality of probes. In turn, the PCB/interposer supports the pad. In some embodiments, the plurality of probes includes a hard core material such as diamond. In other embodiments, the surface of the probes is hardened.

Abstract: An example manipulator for transporting a test head includes: a tower having a base and a track, with the track being vertical relative to the base; an arm to enable support for the test head, with the arm being connected to the track to move the test head vertically relative to the tower; one or more motors to drive movement of the arm along the track; and pneumatic cylinders to control movement of the arm to cause the test head to apply an amount of force to a peripheral device.

Abstract: A frequency visualization apparatus for detecting and displaying one or more specific sets of energy waves based on one or more of defined discrete sets of frequency ranges is disclosed, the apparatus including two or more directional radio frequency antennas for capturing a field of view, such orientation comprising a detector array, each antenna configured to output a specific voltage based on the strength of the intercepted radio waves, two or more voltage amplifiers in communication with the one or more radio frequency antennas, two or more analog to digital converters, a digital memory apparatus connected to the two or more converters for receiving and storing the digital data in a numeric array, a processor connected to the digital memory apparatus, and a display connected to the processor for displaying a visual array comprising visual array elements, each visual array element corresponding to a specific antenna of the detector.

Abstract: Magnetic field sensor arrangement for positioning in a gap formed between end faces (12) of a magnetic core (4), comprising a magnetic field detector (5), a housing (10), and a grounding device (8), the magnetic field sensor and grounding device being mounted to the housing. The grounding device comprises at least one contact (20) elastically supported and configured for electrical contact with the magnetic core. The elastically supported contact is mounted adjacent a sensing portion of the magnetic field sensor and configured for insertion in the magnetic circuit core gap such that the contact elastically biases against the end face of the magnetic core.

Abstract: To provide a current detection circuit capable of detecting with low current consumption that a prescribed current flows into a current measuring resistor. A current detection circuit is equipped with a reference voltage circuit which has two NMOS transistors having different threshold voltages and a resistor, and generates a reference voltage at the resistor, and a comparison output circuit which is comprised of a PMOS transistor, an NMOS transistor, and a measuring resistor connected in series in a manner similar to a PMOS transistor, an NMOS transistor, and a resistor and outputs a comparison result.

Abstract: A test assembly system protects a user from potentially energized equipment. Aspects of the system provide access to the equipment through a socket connection and a test probe assembly that is configured to interface with the socket connection to read voltage or continuity across a bus of the equipment being inspected. The probe assembly shields the user from the equipment to prevent energy or arc flashes from projecting out to contact the user.

Abstract: A power voltage detector comprises voltage sensors for sensing supply voltages; and a logic. The logic combines the sensed supply voltages to generate a logic output indicative of whether the sensed supply voltages have met one or more predefined thresholds. Each of the voltage sensors has diode-connected transistors and passive resistance. The diode-connected transistors and the passive resistance are serially connected for generating an output, where the output is coupled to an input of the logic.

Abstract: A system and method for estimating energy consumption in an HVAC system, the method including the steps of determining a system characteristic value, obtaining an operational condition value, determining a base power consumption value based at least in part on the system characteristic value and the operational condition value, determining an operational run time for the system, and determining an estimated energy consumption based at least in part on the operational run time and the base power consumption value.

Abstract: In a method, device and magnetic resonance (MR) system for determining a system frequency in MR imaging, a frequency spectrum of a region under examination is acquired. A cost function (FOM) is determined that encompasses the difference between a parameterized model function having assigned parameters that is to be optimized, and the acquired frequency spectrum. The cost function is subsequently minimized. Furthermore, the parameters of the optimized parameterized model function assigned to the determined minimum are determined and the system frequency is calculated on the basis of the determined parameters.

Abstract: A sound processing device performs obtaining a first frequency spectrum that corresponds to a first sound signal and a second frequency spectrum that corresponds to a second sound signal, calculating a level difference between a level of each of frequency components in the first frequency spectrum and a level of each of frequency components in the second frequency spectrum, calculating a spread of a distribution of the level difference during a prescribed period for each of the frequency components, and determining a gain to be multiplied to the frequency component in the first frequency spectrum and a gain to be multiplied to the frequency component in the second frequency spectrum in accordance with the spread of the distribution of the level difference.

Abstract: Disclosed examples include systems to determine an on-state impedance of a high voltage transistor, and measurement circuits to measure the drain voltage of a drain terminal of the high voltage transistor during switching, including an attenuator circuit to generate an attenuator output signal representing a voltage across the high voltage transistor when the high voltage transistor is turned on, and a differential amplifier to provide an amplified sense voltage signal according to the attenuator output signal. The attenuator circuit includes a clamp transistor coupled with the drain terminal of the high voltage transistor to provide a sense signal to a first internal node, a resistive voltage divider circuit to provide the attenuator output signal based on the sense signal, and a first clamp circuit to limit the sense signal voltage when the high voltage transistor is turned off.

Abstract: A hand-carriable, single port measurement module of a virtual vector network analyzer is sized and configured so as to be directly connectable to devices typically located within confined spaces normally requiring the use of an intervening test cable and which may be closely spaced to other devices that may need to be tested by other measurement modules. The measurement module includes a single test port extending from a housing wherein the housing is elongated along the axis of insertion of the test port and has a length substantially less than 12 inches. A circuit disposed within the housing is configured to transmit and receive test signals through the test port for measurement of a device under test and to transmit digitized signals representing the test signals through a communication interface of the module to a user interface separate from the housing for presentation to a user.

Abstract: A test chamber for EMC measurement testing, a method for the validation and a method for performing EMC measurement tests in such a test chamber. In order to simplify the validation of an EMC test chamber and the performance of different EMC measurement test procedures in a single test chamber, the novel test chamber for the EMC measurement test is configured for performing different EMC measurement test procedures by providing a plurality of measurement arrangements with different measurement axes. A plurality of antennas are simultaneously arranged in the test chamber. Each of these antennas is assigned in each case to at least one of the measurement test procedures. In order to provide the measurement arrangement for the given measurement test procedure, each of these antennas can be moved from a rest position into a measurement position assigned to the measurement arrangement and back again.

Abstract: The methods and apparatus described herein are designed and configured to allow one user to test cable continuity using a wire-configurable directional connector. The methods and apparatus may transmit a first and second voltage pulse through a first and second wire of a cable under test, respectively, having a wire-configurable directional connector attached. Both voltage pulses travel through the wire-configurable directional connector. The first voltage pulse selectively leaves at least one of the second wire and a third wire of the cable under test and the second voltage pulse selectively leaves the third wire. The methods and apparatus may store a pre-determined pattern of a returning voltage pulse specific to the cable under test, and determine a state of the first, second, and third wires in response to receiving the first and second voltage pulses.

Abstract: A method of evaluating a semiconductor device having an insulated gate formed of a metal-oxide film semiconductor. The semiconductor device has a high potential side and a low potential side, and a threshold voltage that is a minimum voltage for forming a conducting path between the high and low potential sides. The method includes determining a variation of the threshold voltage at turn-on of the semiconductor device by continuously applying an alternating current (AC) voltage to the gate of the semiconductor device, a maximum voltage of the AC voltage being equal to or higher than the threshold voltage of the semiconductor device.

Abstract: A test and measurement instrument, including an input configured to receive a signal-under-test, a user input configured to accept a first trigger event and a second trigger event from a user, a first trigger decoder configured to trigger on an occurrence of the first trigger event and generate a first trigger signal, a second trigger decoder configured to trigger on an occurrence of the second trigger event occurring after the first trigger event and generate a second trigger signal, and an acquisition system configured to acquire the signal-under-test in response to the first trigger signal and store the acquired signal-under-test based on whether the second trigger signal validates or invalidates the first trigger signal.

Abstract: A repair device and a semiconductor device including the same are disclosed, which relate to a technology for storing failure information in a fuse circuit during a test operation. The repair device includes a test circuit configured to test data received from a cell array in response to a test signal, and output a failure signal when a failure occurs. The repair device also includes a count circuit configured to output a counting signal by counting the failure signal, a column failure decision circuit configured to determine whether a column failure occurs in response to the counting signal, and output a write enable signal. Further, the repair device includes a fuse controller configured to output a failed column address in response to the counting signal when the write enable signal is activated, and a column fuse circuit configured to sequentially store the column address.

Abstract: The invention concerns a method for locating a fault affecting an electrical appliance that comprises a communication interface and a female electrical connector, the female electrical connector comprising at least one conductive element mounted movable between an active position and a rest position, the female electrical connector comprising test means connected to the conductive element when same is in the rest position; the locating method comprising: a disconnection step; a test step consisting of testing the communication interface by cooperating with the test means of the female electrical connector; a locating step consisting of locating the fault in the electrical appliance or in an external element.

Abstract: An electronic-component testing device capable of achieving efficient heat-releasing from a self-heating electronic component and efficiently performing a desired test while maintaining the temperature of the electronic component in a predetermined range higher than ordinary temperature.

Abstract: An apparatus is described for burn-in and/or functional testing of microelectronic circuits of unsingulated wafers. A large number of power, ground, and signal connections can be made to a large number of contacts on a wafer. The apparatus has a cartridge that allows for fanning-in of electric paths. A distribution board has a plurality of interfaces that are strategically positioned to provide a dense configuration. The interfaces are connected through flexible attachments to an array of first connector modules. Each one of the first connector modules can be independently connected to a respective one of a plurality of second connector modules, thereby reducing stresses on a frame of the apparatus. Further features include for example a piston that allows for tight control of forces exerted by terminals onto contacts of a wafer.

Abstract: A wafer structure has a plurality of semiconductor die. Each semiconductor die includes circuitry, a test pad for use in testing the circuitry, and a plurality of external pins. The test pad includes first, second, third, and fourth metal lines, a via, and a metal cover that receives a probe. The first and second metal lines are in a first metal layer and run in parallel, are insulated from each other, and are adjacent. The third and fourth metal lines are in a second metal layer run in parallel, are insulated from each other, and run orthogonal to the first and second metal lines. The first via is coupled to the first metal line and the third metal line. One or more external pins are connected to the metal cover.

Abstract: A visualization method for screening electronic devices is provided. In accordance with the disclosed method, a probe is applied to a grid of multiple points on the circuit, and an output produced by the circuit in response to the stimulus waveform is monitored for each of multiple grid points where the probe is applied. A power spectrum analysis (PSA) produces a power spectrum amplitude, in each of one or more frequency bins, on the monitored output for each of the multiple grid points. The PSA provides a respective pixel value for each of the multiple grid points. An image is displayed, in which image portions representing the multiple grid points are displayed with the respective pixel values.

Abstract: Disclosed are techniques for implementing graph-driven verification and debugging of an electronic design. These techniques identify a pair of interest that comprises a target signal and a clock cycle or an event associated with the target signal from a verification or simulation result of an electronic design or a portion thereof. A boundary for relevant driver identification (RDI) operations may be identified for normal termination of the performance of one or more RDI operations. A debug graph may then be generated and stored at least by performing one or more RDI operations for at least the pair of interest based in whole or in part upon the boundary for RDI operations.

Abstract: A system disclosed herein includes an on-chip clock controller (OCC) circuit receiving a test pattern and responsively generating output clock pulses in response to the test pattern. An OCC test circuit is coupled to the OCC circuit and configured to detect data corresponding to output clock pulses generated by the OCC controller circuit and generate corresponding OCC test outputs. A test output logic circuit is configured to receive the OCC test outputs from the OCC test circuit. A debug controller is operable to configure the test output logic circuit to output the OCC test outputs.

Abstract: A method and apparatus for determining a presence, color and/or brightness of a plurality of components in a printed circuit board, where the components are biased either with constant current or with a current pulse.

Abstract: A controller for driving a motor includes a multiphase driver, an analog-to-digital converter (ADC), impedance estimation circuitry, and fault detection circuitry. The multiphase driver is configured to generate drive signals for energizing each motor phase winding. The ADC is configured to digitize voltage and current from each motor phase winding. The impedance estimation circuitry is configured to determine a phasor value for the digitized voltages and for the digitized currents at a predetermined harmonic frequency, and to determine a sequence impedance value based on the phasor values. The fault detection circuitry is configured to identify a fault in the windings of the motor based on the sequence impedance value.

Abstract: To provide a system for controlling power supplies in a device including batteries 12, 13, and 14 by wireless signals with high reliability. The system includes the batteries 12, 13, 14, a power supply control device 1 supplied with power from the batteries 12, 13, and 14, and a controller 15 for making wireless communication with the power supply control device 1. The power supply control device 1 includes a startup unit 37 for receiving a wireless startup signal transmitted from the controller 15 and controlling power supplying from the batteries to the power supply control device, and a communication unit 10 for making wireless communication with the controller. While the startup unit 37 is receiving the wireless startup signal, wireless communication is made by the communication unit 10.

Abstract: A system to accurately determine a battery state of charge (SOC) in an electronic device, in some embodiments, comprises: a battery to provide power to said electronic device; and a fuel gauge coupled to the battery and capable of determining an open circuit voltage (OCV) associated with the battery, wherein the fuel gauge determines said OCV after the battery is installed in the electronic device and before the electronic device enters an operation stage, wherein the fuel gauge determines a state of charge associated with the battery based on said OCV.

Abstract: The present disclosure discloses a battery fuel gauging system, which includes a battery voltage collecting module and a microprocessor module. An input terminal of the battery voltage collecting module is configured to collect a terminal voltage of the battery. The microprocessor module is configured to receive the terminal voltage and estimate the remaining charge in the battery. The microprocessor module estimates an open-circuit voltage of the battery according to the terminal voltage of the battery and a built-in battery model, and further calculates the battery's remaining charge based on SOC-OCV relations of a typical lithium-ion battery. The present disclosure is capable of maintaining the precision of the battery fuel gauging system and can set the battery fuel gauging system inside or outside of the battery.