Patents Issued in December 6, 2018
  • Publication number: 20180344182
    Abstract: The disclosed subject matter related to methods and apparatus for determining brain swelling in a patient as well as predicting an increase in intracranial pressure in the patient. The apparatus can include a transducer such as an ultrasound transducer communicatively connected to a controller via wires or via wireless communications device(s). A monitor and/or alarm device can be provided to notify a practitioner when the controller has determined brain swelling is occurring and/or when an imminent increase in intracranial pressure is likely to occur.
    Type: Application
    Filed: July 25, 2018
    Publication date: December 6, 2018
    Inventor: Kirk Watson Beach
  • Publication number: 20180344183
    Abstract: A multi-lumen catheter for monitoring intrauterine pressure comprising an elongated body configured and dimensioned for insertion into a uterus of a patient, the catheter having a first lumen, a second lumen, and a first balloon at a distal portion. The first lumen communicates with the first balloon and the second lumen has an opening within the uterus for injection of x-ray dye or other fluid into the uterus for imaging the uterine cavity and the fallopian tubes of a patient. The first balloon contains a gas to form along with the first lumen a chamber to monitor pressure within the uterus to thereby determine if excessive pressure is being applied to the fallopian tubes of the patient. A sensor is in communication with the first lumen to measure pressure about a circumferential area of the balloon to measure pressure in the uterus to provide readings of intrauterine pressure.
    Type: Application
    Filed: May 11, 2018
    Publication date: December 6, 2018
    Applicant: Sentinel Medical Technologies, LLC
    Inventors: TIMOTHY McKinney, Marc-Alan Levine
  • Publication number: 20180344184
    Abstract: A multi-lumen catheter for monitoring intramuscular pressure having an elongated body configured and dimensioned for insertion into a compartment of a patient. The catheter has a pressure sensor to determine if excessive pressure is being applied. A sensor is in communication with the lumen to continuously measure pressure to provide continuous readings of intramuscular pressure.
    Type: Application
    Filed: May 25, 2018
    Publication date: December 6, 2018
    Applicant: Sentinel Medical Technologies, LLC
    Inventors: Timothy McKinney, Marc-Alan Levine
  • Publication number: 20180344185
    Abstract: A surgical method aids identification of nerves in a body to help prevent damage to the nerves during surgery to the body proximate the nerves. An electrode introduced to within a body cavity through a catheter is placed proximate a nerve within the body cavity by a laparoscopic or robotic device. An exploratory probe placed in the body cavity is selectively placed along a presumed pathway of the nerve to provide an electrical signal through the nerve to the electrode. An analyzer interfaced with the electrode analyzes the electrical signal received at the electrode to determine the proximity of the exploratory probe to the nerve, allowing mapping of the nerve pathway through the body cavity.
    Type: Application
    Filed: July 19, 2018
    Publication date: December 6, 2018
    Inventors: Randy Fagin, Jon Schiff, Jann Bonfils-Rasmussen
  • Publication number: 20180344186
    Abstract: It is recognized that, because of its unique properties, graphene can serve as an interface with biological cells that communicate by an electrical impulse, or action potential. Responding to a sensed signal can be accomplished by coupling a graphene sensor to a low power digital electronic switch that is activatable by the sensed low power electrical signals. It is further recognized that low power devices such as tunneling diodes and TFETs are suitable for use in such biological applications in conjunction with graphene sensors. While tunneling diodes can be used in diagnostic applications, TFETs, which are three-terminal devices, further permit controlling the voltage on one cell according to signals received by other cells. Thus, by the use of a biological sensor system that includes graphene nanowire sensors coupled to a TFET, charge can be redistributed among different biological cells, potentially with therapeutic effects.
    Type: Application
    Filed: July 20, 2018
    Publication date: December 6, 2018
    Inventor: John H. ZHANG
  • Publication number: 20180344187
    Abstract: Described embodiments include a method for use with a catheter that includes at least one flexible arm to which are coupled a plurality of electrodes. The method includes calculating, by a processor, respective estimated locations of the electrodes while the catheter is within a portion of a body of a subject, fitting a model of the catheter, which models the flexible arm as a piecewise-linear element that includes a plurality of linear segments, to the estimated locations, ascertaining for each of the electrodes, based on respective orientations of one or more of the linear segments per the fitting, whether the electrode is in contact with tissue of the subject, and updating a map of the portion of the body of the subject, in response to ascertaining that at least one of the electrodes is in contact with the tissue. Other embodiments are also described.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 6, 2018
    Applicant: Biosense Webster (Israel) Ltd.
    Inventors: Daniel Osadchy, Meir Bar-Tal
  • Publication number: 20180344188
    Abstract: Cardiac catheterization is performed with a catheter having a basket-shaped assembly at its distal end. A plurality of spline electrodes are disposed on the splines of the assembly. The assembly is configurable in an expanded arrangement wherein the splines bow radially outwardly and in a collapsed arrangement, wherein the splines are arranged generally along the longitudinal axis of the catheter body. A far-field electrode is disposed in the interior of the assembly. An intracardiac electrogram and a far-field electrogram are obtained with at least one of the spline electrodes and the far-field electrode, respectively. The far-field component is removed from the intracardiac electrogram using the far-field electrogram.
    Type: Application
    Filed: August 14, 2018
    Publication date: December 6, 2018
    Inventor: Assaf Govari
  • Publication number: 20180344189
    Abstract: A wearable device configured to acquire and process electrocardiographic measurements, detect lead inversion and correct the acquired measurements for lead inversion is provided. In one example, the wearable device can detect lead inversion by first assessing whether the P-wave of a given electrocardiographic measurement has a negative amplitude, and if the P-wave is found to be negative, the device can determine if the magnitude of the R-wave is smaller than the maximum of the magnitudes of the S-wave and the Q-wave. In another example, the device can be put through an enrollment procedure in which electrocardiographic measurements are taken with the device being worn at known locations on the body. Once the enrollment procedure is completed, when the device is being used, any electrocardiographic results obtained can be compared against the measurements taken during the enrollment phase, and the location of the device on the body can be determined.
    Type: Application
    Filed: August 9, 2018
    Publication date: December 6, 2018
    Inventor: Sorin V. DUSAN
  • Publication number: 20180344190
    Abstract: Medical devices are travel in arteries or veins with an electrical sensor to detect heart nearness. A computer-processor-based system receives and analyzes the sensor signals to provide accurate position of the device based on one or more electrical characteristics. A P-wave and an R-wave of a heartbeat may be extracted from the signals. Energy of the P-wave, the slope of the P wave, and/or a comparison of highest values of the P and R waves can be provided, potentially over time as the device is advanced. A graphical interface may display these values, a speaker may provide pings or beeps associated with values, or any other output that can be sensed may be used. Thresholds associated with reaching the heart may trigger notifications when detected in the sensor signals, such as maximum energy of a P-wave over time, inversion of slope of the P-wave, and/or P-wave amplitude equaling R-wave amplitude.
    Type: Application
    Filed: August 6, 2018
    Publication date: December 6, 2018
    Inventors: Ashim Roy, Govind Rajagopalan, Avin Agarwal
  • Publication number: 20180344191
    Abstract: A system and method for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer is provided. A plurality of R-wave peaks are identified in a set of ECG data and a difference between recording times of successive pairs of the R-wave peaks are calculated as R-R intervals. A heart rate associated with each time difference is determined. An R-R interval plot of the ECG data is formed. The R-R intervals are plotted along an x-axis of the R-R interval plot and the heart rates associated with the R-R intervals are plotted along a y-axis of the R-R interval plot. A diagnostic composite plot is generated, including the R-R interval plot, a near field view of a portion of the ECG data, and an intermediate field view of a different portion of the ECG data for diagnosis of a cardiac event.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Inventors: Gust H. Bardy, Ezra M. Dreisbach
  • Publication number: 20180344192
    Abstract: In accordance with an aspect of the present invention, a system and method allows for the assessment of health and mortality based on dynamic nonlinear calculations of self-similar fluctuation patterns in a time series of QT intervals and of other physiological signals, such as RR intervals, temperature, blood pressure, respiration, saturation of peripheral oxygen, intracardiac pressures, and electroencephalogram. In order to nonlinearly determine health and mortality, time series of QT intervals and of other physiological signals (e.g., RR intervals) are simultaneously obtained, and entropy values are calculated for each signal over the same temporal interval. “EntropyX” is calculated from relative changes between moments and entropy of QT intervals and those of other physiological signals over seconds to days. The absolute and relative entropy values at a specific time point and/or subsequent changes in entropy over future time points can be used to determine a treatment plan for the subject.
    Type: Application
    Filed: August 3, 2018
    Publication date: December 6, 2018
    Inventors: Deeptankar DeMazumder, Gordon Tomaselli
  • Publication number: 20180344193
    Abstract: Embodiments disclose a blood pressure parameter detection method. The method includes: detecting, by user equipment UE, an electrocardiogram ECG signal of a user by using a first ECG contact and a second ECG contact that are connected to an ECG detection circuit of the UE; when determining that the detected ECG signal matches a pre-stored reference ECG signal, enabling, by the UE, a photoplethysmogram PPG detection circuit, and detecting a PPG signal of the user by using a PPG detection point connected to the PPG detection circuit; and when determining that the detected PPG signal matches a pre-stored reference PPG signal, enabling, by the UE, a blood pressure detection application, and processing the detected ECG signal and the detected PPG signal by using the blood pressure detection application to obtain a blood pressure parameter of the user.
    Type: Application
    Filed: November 26, 2015
    Publication date: December 6, 2018
    Inventors: Yonglin GUI, Bo YANG, Qizhi ZHAN, Honggang LI, Zexu QIAN
  • Publication number: 20180344194
    Abstract: A device provides a first data signal that indicates an activity of at least one muscle of a patient that is relevant for an inspiratory breathing effort and a second data signal that indicates an activity of at least one muscle of the patient that is relevant for an expiratory breathing effort. The data signals are generated from electromyography (EMG) signals detected by surface electromyography sensors. A computer is configured to determine breathing phase information on the basis of a breathing signal and to check at least one of the electromyography signals or at least one of the separated signals for detectability of a heart signal component and further to assign the signals to an inspiratory breathing activity as well as to an expiratory breathing activity of the patient as a function of the breathing phase information.
    Type: Application
    Filed: November 21, 2016
    Publication date: December 6, 2018
    Inventors: Marcus EGER, Philipp ROSTALSKI, Herbert BUCHNER
  • Publication number: 20180344195
    Abstract: Systems, articles, and methods for surface electromyography (“EMG”) sensors that combine elements from traditional capacitive and resistive EMG sensors are described. For example, capacitive EMG sensors that are adapted to resistively couple to a user's skin are described. Resistive coupling between a sensor electrode and the user's skin is galvanically isolated from the sensor circuitry by a discrete component capacitor included downstream from the sensor electrode. The combination of a resistively coupled electrode and a discrete component capacitor provides the respective benefits of traditional resistive and capacitive (respectively) EMG sensor designs while mitigating respective drawbacks of each approach. A wearable EMG device that provides a component of a human-electronics interface and incorporates such capacitive EMG sensors is also described.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 6, 2018
    Inventors: Cezar Morun, Stephen Lake
  • Publication number: 20180344196
    Abstract: An information processing method is executed by a computer having a control unit, wherein the control unit executes: acquiring a plurality of biological signals; detecting for each predetermined time unit a peak part of the respective biological signals; attaching identical identification information to one or a plurality of peak parts forming an identical peak when attaching peak identification information to each of the biological signals; and extracting a combination of corresponding peaks from at least two biological signals on the basis of the identification information of each time unit of the at least two biological signals.
    Type: Application
    Filed: November 12, 2015
    Publication date: December 6, 2018
    Applicant: JINS Inc.
    Inventor: Taiki Komoda
  • Publication number: 20180344197
    Abstract: The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.
    Type: Application
    Filed: March 29, 2018
    Publication date: December 6, 2018
    Inventors: Jay NEITZ, Maureen NEITZ, James A. KUCHENBECKER, William W. HAUSWIRTH
  • Publication number: 20180344198
    Abstract: In a method for optimizing a magnetic resonance (MR) examination to be performed with an MR scanner on a patient, a token is detected that identifies a medical aid that is to be present in the MR scanner during the examination, in particular to identify an implant implanted in the patient, a medical device to be used during the MR examination or a medical prosthesis worn by the patient. At least one restriction for the planned MR examination is determined in a computer as a function of the token.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Applicant: Siemens Healthcare GmbH
    Inventors: Matthias Gebhardt, Stephan Nufer
  • Publication number: 20180344199
    Abstract: Methods and systems are provided for improved delivery of agents to targeted regions of the brain, by the use of placement coordinates that provide for optimal placement of delivery cannula. By optimizing the cannula placement, reproducible distribution of infusate in the targeted region of the brain is achieved, allowing a more effective delivery of therapeutics to the brain.
    Type: Application
    Filed: July 26, 2018
    Publication date: December 6, 2018
    Inventors: Krystof S. Bankiewicz, Dali Yin
  • Publication number: 20180344200
    Abstract: IMD devices, systems, and treatment methods are discussed and disclosed. An IMD having electrodes for placement in an internal thoracic vein (ITV) of a patient may be employed to facilitate electrical impedance tomography (EIT) imaging. An alternating current (A/C) may be applied using the electrodes and impedances may be determined that are useful to produce a tomographic image.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: PRAMODSINGH HIRASINGH THAKUR, JEFFREY E. STAHMANN, VIKTORIA A. AVERINA, QI AN, G. SHANTANU REDDY, JAMES O. GILKERSON, KEITH R. MAILE
  • Publication number: 20180344201
    Abstract: This invention relates to a method of catheter and radiating coil location in a human body. In particular, when a radiating coil is used in conjunction with a catheter, a coil locating device can be used to determine the distance the coil is from the device and its depth in the patient's body. A display is provided that shows both a reference image of a portion of a non-subject body and an image of the coil located on the display with reference to the reference image. This is achieved by locating the coil-locating device on a predetermined landmark on the patient's body. The coil and its signal wires can be incorporated into a stylet, guide wire or a catheter. The coil locating device can be orientated towards the head of the patient and for an axis of the device to be aligned with the mid sagittal plane of the patient.
    Type: Application
    Filed: July 31, 2018
    Publication date: December 6, 2018
    Inventors: William John Besz, Donald Philip Chorley, Stuart Brasted, Robert Anthony Walker
  • Publication number: 20180344202
    Abstract: Apparatus, including a probe having a proximal end and a distal end, the probe being configured to be inserted into an organ of a human patient and defining a probe axis. At least two conductors are positioned on the probe at the distal end. The apparatus includes at least two flexible conductive splines, each conductive spline having a first termination and a second termination, the first terminations being electrically connected together at a region on the probe axis beyond the distal end, each second termination being electrically connected to a respective one of the conductors, the splines being configured to bend into respective arcuate forms that encompass a volume. The apparatus also includes a processor configured to receive voltages induced on the splines via the conductors and to calculate a position and orientation of the volume in response to the received voltages.
    Type: Application
    Filed: May 4, 2018
    Publication date: December 6, 2018
    Inventors: Meir Bar-Tal, Avram Dan Montag
  • Publication number: 20180344203
    Abstract: A minimally invasive surgical instrument using 3-axis magnetic positioning, system and methods thereof. This invention describes two key ideas that enable the development of a magnetic position system based on integrated anisotropic magnetoresistive (AMR) magnetic field sensors. This achieves the resolution, power and area targets necessary to integrate 3 axes anisotropic magnetoresistance (AMR) sensors along with the Analog Front End integrated circuit (IC) in a 4 mm by 350 um integrated solution for catheter applications. The stringent area and power dissipation requirements are met by development through both system level solutions for higher field strengths and a minimally necessary Analog Front End (AFE) to meet the 1 mm rms resolution requirement in the power dissipation and area budget.
    Type: Application
    Filed: June 1, 2018
    Publication date: December 6, 2018
    Applicant: Analog Devices Global
    Inventors: Yogesh Jayaraman SHARMA, Christopher W. HYDE, Brendan CRONIN, Jochen SCHMITT
  • Publication number: 20180344204
    Abstract: A system for generating a manual input on a shape sensing fiber includes a shape enabled device (102) including one or more shape sensing optical fibers. An input device (106) is configured on a portion of the one or more shape sensing optical fibers, wherein a change in optical shape sensing data associated with the input device distinguishable from other shape sensing data, generates an input signal. A processor system (112) is configured to receive the input signal and perform an action responsive to the input signal.
    Type: Application
    Filed: November 11, 2016
    Publication date: December 6, 2018
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: Molly Lara Flexman, Sander Hans Denissen, Wilhelmus Henrica Gerarda Maria VAN DEN BOOMEN, Neriman Nicoletta KAHYA
  • Publication number: 20180344205
    Abstract: Devices and methods for vascular navigation, assessment and/or diagnosis are described which determine the location of the tip of a vascular catheter using the introduction of a medium with a measurable parameter (e.g., temperature, light reflection, sound reflection, etc.) and sensing and measuring the measurable parameter as the catheter is advanced. Measurements of the parameter are tracked over time, recorded and analyzed. The value of the parameter and/or the shape of the parameter value vs. time curve may be used in the analysis. For example, curve amplitude, variability, standard deviation, slope, etc. may be used in the analysis of catheter location.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 6, 2018
    Applicant: Piccolo Medical, Inc.
    Inventors: Alexey SALAMINI, Eric YU, Daniel R. BURNETT
  • Publication number: 20180344206
    Abstract: A physiological parameter processing apparatus includes an input interface section that acquires respiration data produced based on a respiratory gas that is obtained from at least one of a mouth and nose of a subject, and an analyzing section that analyzes in real time the respiration data acquired through the input interface section, and that produces analysis result data which can be displayed in real time.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Hironori KOBAYASHI, Yukio NONAKA, Kazuri HIGASHI, Takayuki SUGIYAMA
  • Publication number: 20180344207
    Abstract: A respiratory pressure sensor includes an input that receives respiratory as from at least one of a nasal cavity or an oral cavity of a subject, a pressure sensor that detects respiratory pressure of the respiratory gas received from the input, a signal processor that performs signal processing on the respiratory pressure detected by the pressure sensor and generates respiration data, and an output that outputs the respiration data to an external device.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Anna YAMAGISHI, Makoto TSUJI, Kazuri HIGASHI, Takayuki SUGIYAMA
  • Publication number: 20180344208
    Abstract: There is provided a respiration estimation method. The respiration estimation method includes a first step (S107) of estimating a breathing rate of a subject based on each of a time-series signal of first data relating to a cardiac function of the subject and a time-series signal of second data relating to an acceleration by a respiratory motion of the subject, a second step (S108) of estimating a breathing rate obtained by filtering noise using a Kalman filter for each of the breathing rate estimated based on the first data and the breathing rate estimated based on the second data, and a third step (S109) of executing weighted averaging processing for the plurality of estimated values of the breathing rates obtained in the second step.
    Type: Application
    Filed: November 25, 2016
    Publication date: December 6, 2018
    Inventors: Takayuki Ogasawara, Takurou Tajima, Kei Kuwabara, Nobuaki Matsuura, Ryoichi Kasahara
  • Publication number: 20180344209
    Abstract: The present invention relates to quality control of pulmonary function test (PFT) devices. In particular, but not by way of limitation, the present invention relates to systems and methods for characterizing or verifying the measurement accuracy of pulmonary function testing devices used for measuring dynamic lung volumes (tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), divisions thereof, and any other suitable dynamic lung volume) using spirometry, static and/or absolute lung volumes (total lung capacity (TLC), residual volume (RV), divisions thereof, and any other suitable absolute lung volume) using washout, dilution, and/or plethysmographic methods, and/or gas exchange, such as single-breath determination of carbon monoxide uptake in the lung (DLCO).
    Type: Application
    Filed: June 1, 2018
    Publication date: December 6, 2018
    Inventors: John Francis HIGGINS, JR., Eric NORGARD
  • Publication number: 20180344210
    Abstract: A wearable weight scale, including an extensible fluid-filled insole for measuring and producing data relating to pressure changes within the extensible fluid-filled insole; a transceiver disposed about the extensible fluid-filled insole for transmitting the data; and one or more electronic devices for wirelessly receiving the transmitted data for displaying the data to a user.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Inventor: Marcus G. Pestl
  • Publication number: 20180344211
    Abstract: The invention relates to an assistance device intended for a person (1) suffering from motor disorders of neurological origin, comprising: an accelerometer suitable for being worn by the person to measure accelerations; and storage means storing a plurality of previously defined alert acceleration threshold values; and means (5) for emitting an auditory stimulation perceptible to the person wearing the accelerometer; and calculation means configured to perform the following steps: a) determine a posture of the person from the measured accelerations; b) compare the accelerations measured by said accelerometer in the first direction in relation to at least one anticipatory acceleration threshold value associated with said posture; c) command the emission of an auditory stimulation as a function of the crossing of said anticipatory acceleration threshold value associated with said posture for a determined time associated with said anticipatory acceleration threshold value.
    Type: Application
    Filed: March 3, 2016
    Publication date: December 6, 2018
    Inventors: Sébastien TEISSIER, Jordan MIRON
  • Publication number: 20180344212
    Abstract: Systems and methods for monitoring and treating patients with heart failure are described. A signal receiver may receive a heart sound (HS) signal and an impedance signal sensed from the patient. A heart sound detector circuit may use at least the received impedance signal to determine a HS detection window, and detect a HS component indicative of cardiac diastolic function from the received HS signal within the HS detection window. The system may include a heart failure detector circuit that may generate a cardiac diastolic function indicator (DFI) using the detected HS component and, in certain examples, may detect worsening heart failure using the generated DFI. The system may include a therapy circuit to deliver or adjust an electrostimulation therapy based on DFI.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Qi An, Pramodsingh Hirasingh Thakur
  • Publication number: 20180344213
    Abstract: A biological information measurement device includes: a pressure sensor which includes a plurality of pressure detecting elements arranged in one direction; a pressing mechanism which presses the pressure sensor against a wrist of a person to he measured; a biological information calculating section which calculates biological information based on information of pressure pulse waves which are detected by the pressure detecting elements; and a personal identifying section which determines whether the person to be measured is a registered user who is previously registered or not, based on data indicating relationships between information of pressure signals which are detected by the pressure detecting elements of the pressure sensor in a pressed state where the pressure sensor is pressed against the wrist by the pressing mechanism, and positions of the pressure detecting elements in the one direction.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 6, 2018
    Inventors: Yuya OTA, Hirotaka WADA, Masaaki KASAI, Ayako KOKUBO
  • Publication number: 20180344214
    Abstract: A posture and breathing improvement device, system, and method. The system for improving posture and deep breathing may comprise: a sensor device; posture/breathing improvement software program, comprising one, both, or a combination of a posture improvement system interface and a breathing improvement system interface; and one or more user devices. The sensor device may be physically associated with a user and may communicate with the posture improvement software program. The sensor device may comprise: one or more sensors for monitoring positions and movements of the user. The system may calculate one or more optimum postural positions and breathing exercises for the user, based on data communicated by the sensor device and collected information about the user. The system may monitor a conformance of the user with the optimum postural positions and may display the conformance on the posture improvement system interface.
    Type: Application
    Filed: August 6, 2018
    Publication date: December 6, 2018
    Inventor: Kenneth Lawrence Rosenblood
  • Publication number: 20180344215
    Abstract: Dynamic tracking of user-based activity is provided as a function of information received from a plurality of data sources. Tracking of user activity information via a first application occurs correlated to steps taken by a user over a period of time. A health score associated with the user is presented in a GUI. Further, communication with a second application occurs during gameplay. Moreover, the at least one computing device is configured to combine, using the first application, the tracked user activity information with at least a portion of the user interaction information into an activity value. The computing device updates the health score using the activity value. Still further, the computing device is configured to store the updated health score in association with a record concerning the user, and to cause a notification on the mobile computing device of the updated health score when the first application is not executing.
    Type: Application
    Filed: July 17, 2018
    Publication date: December 6, 2018
    Inventors: Peter Ohnemus, Andre Naef, Laurence Jacobs, David Leason
  • Publication number: 20180344216
    Abstract: Indication device comprising an elongated indication pin connected to a base, said base suitable to be arranged on or to the surface of a body.
    Type: Application
    Filed: November 29, 2016
    Publication date: December 6, 2018
    Inventor: Finn Christian Simonsen
  • Publication number: 20180344217
    Abstract: A system and method for collecting motion data using a fitness tracking device located on an arm of a user, detecting that the arm is constrained based on the motion data, estimating a stride length of the user based on the motion data and historical step cadence-to-stride length data, calculating fitness data using the estimated stride length, and outputting the fitness data to the user.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 6, 2018
    Inventors: Daniel J. Perry, Edith M. Arnold, Hung A. Pham, Jonathan M. Beard, Karthik Jayaraman Raghuram, Vinay R. Majjigi
  • Publication number: 20180344218
    Abstract: Embodiments herein relate to chemical sensors for detecting a physiological analyte. In an embodiment, an implantable medical device including a chemical sensor for detecting an ion concentration in a bodily fluid is provided. The chemical sensor can include a sensing element having an outer barrier layer forming a top, a bottom, and opposed sides, where the top of the outer barrier layer can be created from a polymeric matrix permeable to sodium ions, potassium ions, and hydronium ions. An active agent can be disposed within the top of the outer barrier layer, the active agent having anti-inflammatory effects. The chemical sensor can include an optical excitation assembly configured to illuminate the sensing element. The chemical sensor can also include an optical detection assembly configured to receive light from the sensing element. Other embodiments are also included herein.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Yingbo Li, Michael John Kane, Jeffrey E. Stahmann, Keith R. Maile
  • Publication number: 20180344219
    Abstract: Disclosed are systems and methods for measuring blood oxygen saturation via a multiwavelength pulse oximeter. The system comprises a multi-wavelength pulse oximeter with an LED array, a patient monitor connected to the multi-wavelength pulse oximeter, a medical data network for querying an at least one wavelength associated with a patient condition, an algorithm network for providing subscription based algorithms to process sensor data, and a user interface on the patient monitor for configuring a pulse oximeter's scanning mode, for querying the at least one wavelength associated with a patient condition, and for displaying a plethysmograph.
    Type: Application
    Filed: September 21, 2016
    Publication date: December 6, 2018
    Inventors: John CRONIN, Joseph BODKIN
  • Publication number: 20180344220
    Abstract: Methods, systems and devices for providing improved calibration accuracy of continuous and/or in vivo analyte monitoring systems based at least in part on insulin delivery information are provided. Many of the embodiments disclosed herein can determine appropriate conditions for performing a calibration of the analyte sensor in view of the scheduled delivery of insulin or administered insulin amount. One or more other parameters or conditions can also be incorporated to improve calibration accuracy including, for example, the physiological model associated with a patient, meal information, exercise information, activity information, disease information, historical physiological condition information, as well as other types of information. Furthermore, according to some embodiments, calibration of the analyte sensor can be delayed or not performed at all, if appropriate conditions are not met.
    Type: Application
    Filed: March 8, 2018
    Publication date: December 6, 2018
    Inventors: Gary Alan Hayter, Erwin Satrya Budiman
  • Publication number: 20180344221
    Abstract: The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventor: Jason C. Heikenfeld
  • Publication number: 20180344222
    Abstract: The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventor: Jason C. Heikenfeld
  • Publication number: 20180344223
    Abstract: The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventor: Jason C. Heikenfeld
  • Publication number: 20180344224
    Abstract: The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Inventor: Jason C. Heikenfeld
  • Publication number: 20180344225
    Abstract: A blood sugar measuring apparatus includes a carrier, a measuring unit installed in the carrier, a calculation unit installed in the carrier and electrically connected to the measuring unit, a display unit installed in the carrier and electrically connected to the calculation unit, and a power unit installed in the carrier and electrically connected to the measuring unit, the calculation unit and the display unit. The blood sugar measuring apparatus is easy to measure the blood sugar without a significant psychological burden and discomfort, but with higher accuracy.
    Type: Application
    Filed: May 8, 2018
    Publication date: December 6, 2018
    Inventors: MIIN-TSONG YANG, PO-CHIH WU, TZU-PAI KAO, HSUEH-CHUAN LIAO, TZU-HUI CHEN, CHAO-JUNG CHEN
  • Publication number: 20180344226
    Abstract: An apparatus obtaining a pH level of a tissue comprises an array of at least three optical sensors configured to absorb light shined on the tissue and thereby obtain at least three electronic digital signals, wherein the first electronic signal A1(X,t) represents the light absorbed by the tissue in location X=(X,Y,Z) at time t and at wavelength L1, and similarly the second and third electronic signal A2(X,t) and A3(X,t), and a finite absorption range of the three wavelength L1, L2 and L3 is such that 0<=A3(X,t)<=A2(X,t)<A1(X,t); and an electronic processing unit receives the signals and applies an ordered monotone function, F1, to the tissue, to spatial temporal information of each wavelength, F1 used by a transfer function for presentation as a LookUp Table connecting actual values computed by F1 and an actual pH of the tissue in location X at time t.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 6, 2018
    Inventor: Yosef SEGMAN
  • Publication number: 20180344227
    Abstract: A system and method comprising a pulse oximeter with a pulse width modulator that periodically tests the en wavelengths emitted at the pulse width's upper and lower limits in order to ensure that the median pulse width is emitting the wavelength specified by the manufacturer. The system comprises a pulse oximeter that has LED emitter(s), photodetectors, a pulse width modulator and memory. The specifications database contains data relating to the wavelength specified by the manufacturer. The calibration software will periodically test the LED to ensure the correct wavelength is being emitted by the LED in order to detect the proper constituents in the patient's blood. The testing is conducted whenever the pulse oximeter is energized and then again at a specified interval until power is disconnected from the pulse oximeter. Each test includes increasing the pulse width until an error is detected, recording the upper limit of the pulse width and the corresponding wavelength before an error occurred.
    Type: Application
    Filed: December 1, 2016
    Publication date: December 6, 2018
    Inventors: John CRONIN, Michael D'ANDREA
  • Publication number: 20180344228
    Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.
    Type: Application
    Filed: November 30, 2016
    Publication date: December 6, 2018
    Inventor: Dvir YELIN
  • Publication number: 20180344229
    Abstract: A method for suggesting additional tests based on a patient's health status and medical records comprising: inputting via a user interface the patient's medical records; acquiring health parameters of the patient; determining the patient's health status based on the acquired health parameters; transmitting to a network server the determined patient's health status and the inputted patient's medical records to determine a health template based on the transmitted patient's health status and patient's medical records; receiving from the network server the determined health template; extracting from the received health template an oxygen saturation level threshold and a pulse rate threshold range; acquiring an oxygen saturation level and a pulse rate of the patient via a pulse oximeter; and suggesting additional tests from the acquired health template when the acquired oxygen saturation level and pulse rate are not within the extracted oxygen saturation level threshold and pulse rate threshold range.
    Type: Application
    Filed: September 22, 2016
    Publication date: December 6, 2018
    Inventors: John CRONIN, Joseph George BODKIN
  • Publication number: 20180344230
    Abstract: Personal diagnostic devices including diagnostic patches (bio-patches) and interactive medical bracelets (bio-bracelets) are provided with a skin/patch interface, at least one analysis layer, a signal processing layer, and a user output interface. Embodiments of the interactive diagnostic devices may include micro-fluidic circuits with reaction chambers, analysis chambers, mixing cambers, and various pre-disposed chemistries or reagents for performing a wide verity of tests by trans-dermal transport of blood or perspiration. Sample collection chambers for the fluidic circuit may include minimally invasive tubules that penetrate the skin surface to acquire blood samples from capillaries near the epidermis. Alternate implementations of the personal diagnostic device may be equipped with logic processing, input/output devices, acoustic microphones, cryogenic circuits, embedded processors, electrical control circuitry, and battery current sources or photovoltaic sources of electrical power.
    Type: Application
    Filed: May 31, 2018
    Publication date: December 6, 2018
    Inventors: Brigitte Chau Phan, Andrew Atilla Pal, Ramoncito M. Valencia, Donald Bollella
  • Publication number: 20180344231
    Abstract: Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a sample from a source of fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample. The analyte monitoring system can be connected to the fluid source via a connector that is configured to improve fluid flow and reduce blood clotting risk. These goals can be accomplished, for example, by employing coatings in or on a connector, positioning a resilient substance at or near the junction, by reducing dead space volume, by using resiliency to improve fit, by extending a portion of one connector to better mate with a portion of another connector, etc.
    Type: Application
    Filed: July 23, 2018
    Publication date: December 6, 2018
    Inventors: Michael Butler, Eugene Lim, Craig Johnson