Abstract: A bone fastener includes a screw shaft having a proximal portion and a distal portion. The proximal portion is formed by a first manufacturing method and defines a distal face. The distal portion is formed onto the distal face by a second manufacturing method. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Devices and methods mix a bone cement and comprise at least one cartridge, wherein the cartridge comprises in its interior a cylindrical mixing chamber, a discharge piston movable in the cylindrical mixing chamber in the longitudinal direction and sealable against the walls of the mixing chamber, a mixing device for thoroughly mixing the content of the mixing chamber, which is arranged in the interior of the mixing chamber. The mixing device is operable externally via a mixing rod and the mixing rod is guided through a passage in the discharge piston such that it can be rotated and displaced in the longitudinal direction by the discharge piston. The cartridge comprises a discharge opening opposite the discharge piston, wherein, in the mixing chamber, a first component is contained between the discharge piston and the discharge opening, wherein a monomer fluid as a second component is introducable through the discharge opening into the mixing chamber.

Abstract: A bone fixation system includes at least one bone fixation member and a bone fixation instrument. The bone fixation member includes a strap and a locking mechanism. The strap can be pulled through the locking mechanism so as to form a loop about a target bone so as to secure first and second bone segments in an approximated, compressed configuration. The bone fixation instrument is configured to apply tension to the loop about the target bone. The fixation instrument includes a tension assembly that is configured to secure a free end of the bone fixation member to the fixation instrument. The tension assembly is further configured to pull the free end so as to increase tension in the loop while the tension in the loop is less than a select tension. The tension assembly is unable to further increase tension in the bone fixation member once the tension in the bone fixation member has reached the select tension.

Abstract: Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail.

Abstract: An orthopaedic surgical instrument for use in disassembling an orthopaedic prosthesis includes a main component, a rod, and a spindle. The main component has a housing and an elongated body extending from the housing with a passageway is defined in the elongated body. The rod has an elongated shaft, with a greater length than the elongated body, extending from the head of the rod and configured to pass through the main component. The spindle threads into the housing to move the rod along a longitudinal axis.

Abstract: The present invention relates to robotic surgical devices. More specifically, the present invention relates to robotic surgical devices that can be inserted into a patient's body and can be positioned within the patient's body.

Abstract: Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.

Abstract: Devices, systems, and methods for degassing fluid prior to applying fluid to a treatment site during ablation therapy are provided. In one embodiment, an ablation system can include an elongate body, an ablation element, a heating assembly, and a fluid source. Fluid in the fluid source can be at least partially degassed prior to being provided as part of the system, or, in some embodiments, a degassing apparatus can be provided that can be configured to degas fluid within the system prior to applying the fluid to the treatment site. The degassing apparatus can include one or more gas-permeable and fluid-impermeable tubes disposed therein, which can allow gas to be removed from fluid passing through the apparatus. Other exemplary devices, systems, and methods are also provided.

Abstract: A device for treating a tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip arms, proximal ends of which are slidably received within the channel of the capsule so that the clip arms are movable between an open configuration, and a closed configuration. A core member is coupled to the clip arms, the core member including a proximal portion and a distal portion releasably connected to one another so that, when the core member is subjected to a predetermined load, the proximal and distal portions are separated from one another. An electrically conductive control member is connected to the core member, a proximal end of the connected member connected to a power source for delivering an electrical current to the clip arms.

Abstract: An end effector assembly (12) for an electrosurgical instrument comprises a pair of opposing first and second jaw members (13, 14), at least one of the jaw members being movable relative to the other between a first open position in which the jaw members are disposed in a spaced relation relative to one another, and a second closed position in which the jaw members cooperate to grasp tissue therebetween. The first jaw member (13) includes a first tissue-contacting surface (17) and the second jaw member includes a second tissue-contacting surface (19). The first tissue-contacting surface (17) comprises a plurality of ridges (23) extending parallel to one another in a first longitudinal direction, and the second tissue-contacting surface (19) comprises a plurality of ridges (24) extending parallel to one another in a second longitudinal direction, the first longitudinal direction being different from the second longitudinal direction.

Abstract: Methods and devices are provided for retracting a cutting assembly in the event of a failure on a motorized electrosurgical device. For example, a surgical device is provided that includes a handle portion with an elongate shaft that has first and second jaws configured to engage tissue. The device also includes a cutting assembly configured to cut tissue engaged between the first and second jaws and a drive shaft that moves the cutting assembly. A gear box is provided in the device that is coupled to the drive shaft, and a motor is coupled to the gear box for driving the gear box. The device has a normal mode in which power can be provided to the motor to drive the gear box, and the device has a bailout mode in which the motor and gear box can be manually rotated as a unit.

Abstract: Apparatus and method for detecting metal disturbance during a medical procedure includes a probe having an insertion tube, a joint and a joint sensor, contained within the probe, for sensing a position of the insertion tube. The joint sensor has first and second subassemblies that are magnetic transducers. A processor is used for measuring force using the joint sensor, and has a threshold field value stored therein. The processor compares a sensed field value to the threshold field value and identifies a presence metal when the sensed field value is greater than the threshold field value.

Abstract: A method, including selecting a first maximum radiofrequency (RF) power to be delivered by an electrode within a range of 70 W-100 W, and selecting a second maximum RF power to be delivered by the electrode within a range of 20 W-60 W. The method also includes selecting an allowable force on the electrode within a range of 5 g-50 g, selecting a maximum allowable temperature, of tissue to be ablated, within a range of 55° C.-65° C., and selecting an irrigation rate for providing irrigation fluid to the electrode within a range of 8-45 ml/min. The method further includes performing an ablation of tissue using the selected values by initially using the first power, switching to the second power after a predefined time between 3 s and 6 s, and terminating the ablation after a total time for the ablation between 10 s and 20 s.

Abstract: Techniques for treating a tumor and vaccinating against cancer are described. The techniques include treating the tumor by positioning electrodes over an interface between the tumor and non-tumor tissue and applying sub-microsecond pulsed electric fields. The positioning is facilitated by an imaginary contour line of a threshold value of the electric field. In an example, the imaginary contour line is overlaid over images that include the tumor such that the electrodes are properly positioned over the tumor. The techniques also include vaccinating against cancer by passing sub-microsecond pulsed electric fields through tumor cells of a subject sufficient to cause the tumor cells to express calreticulin on surface membranes. The tumor cells are extracted and introduced with the expressed calreticulin into the subject or another subject, thereby providing a vaccination.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, an actuation lever of the handle, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, and an optic fiber disposed within an inner bore of the handle and the flexible housing tube. An actuation of the actuation lever may gradually curve the flexible housing tube and the optic fiber. An actuation of the actuation lever may gradually straighten the flexible housing tube and the optic fiber.

Abstract: A surgical assistive apparatus and method to provide assistance during surgery, includes an organ boundary localization circuit that selects a test video frame from a captured sequence of video frames and derives a first global region boundary of an internal organ of interest in the selected test video frame by integration of an appearance likelihood result, a global segmentation result, and a global edge detection result associated with the internal organ of interest. A plurality of local region boundaries are determined for a plurality of local sub regions of the internal organ of interest and a second global region boundary is generated for the internal organ of interest based on the determined plurality of local region boundaries and the first global region boundary. The internal organ of interest is localized based on the generated second global region boundary.

Abstract: An optical tracking system and a method using the same capable of detecting an exact spatial position and a direction of a target regardless of the distance from the target to be calculated is disclosed. The optical tracking system and a method using the same according to an embodiment of the present invention has an effect of expanding an available area by detecting an exact spatial position and a direction of a target regardless of the distance from the target to be calculated, as well as, a system downsizing is also achieved by significantly reducing size of the marker unit compared with conventional system.

Abstract: A multipoint detection fiber sensor including a plurality of sensing parts at a plurality of positions is provided. The sensing parts are able to detect curve amounts respectively. The multipoint detection fiber sensor includes a plurality of optical fibers arranged in an overall effective detection area that is an extent in which the multipoint detection fiber sensor detects curve amounts. Each of the optical fibers includes the plurality of sensing parts. The multipoint detection fiber sensor also includes a light source which supplies light to the optical fibers and a light receiver which receives light emitted through the optical fibers to which light is supplied. Furthermore, an insertion apparatus into which the multipoint detection fiber sensor is incorporated is provided.

Abstract: A medical manipulator includes: an insertion section having a main movable section and a distal end rigid section; a manipulator at which a treatment section is provided; an auxiliary movable section configured to move the treatment section; an imaging section configured to acquire an image in a field-of-vision range; a manipulation unit configured to output an instruction that specifies a position to which the treatment section is moved; a display configured to display the image; a determination unit configured to determine whether a condition is a partial movement condition or an entire movement condition when the determination unit receives the instruction; and a driving unit configured to drive the auxiliary movable section, the main movable section, and the imaging section based on determination of the determination unit.

Abstract: A surgical system (200) includes a surgical instrument (260) that is sensitive to backlash that would adversely affect the transmission of controlled torque and position to the surgical instrument. The surgical instrument (260) is coupled to motors in a surgical instrument manipulator assembly (240) via a mechanical interface. The combination of the mechanical interface and surgical instrument manipulator assembly (240) have low backlash, e.g., less than 0.7 degrees. The backlash is controlled in the surgical instrument manipulator assembly (240). From the drive output disk (545) in the surgical instrument manipulator assembly to the driven disk (964) of the surgical instrument, the mechanical interface has zero backlash for torque levels used in surgical procedures.

Abstract: A surgical robot system includes a support structure for positioning relative to a patient. The support structure includes a plurality of mounting structures. One or more robotic tool cassettes that are configured to interchangeably connect with any of the mounting structures. Each tool cassette includes a concentric tube manipulator and a transmission for operating the concentric tube manipulator. The support structure also includes a tube collector including a tube assembly associated with each of the mounting structures. The tube assemblies are configured to receive the concentric tube manipulators and guide the manipulators to extend along predetermined trajectories relative to each other.

Abstract: Various exemplary systems, devices, and methods are provided for locking articulating surgical tools. In general, a surgical tool can include an elongate shaft having at a distal end thereof an end effector configured to engage tissue. The end effector can be configured to articulate relative to the elongate shaft. The surgical tool can include a locking mechanism configured to lock the end effector at its current angled orientation. The surgical tool can be configured to releasably couple to a robotic surgical system configured to control a variety of movements and actions associated with the surgical tool.

Abstract: The subject invention provides a surgical instrument support assembly which includes an enclosure defining an opening; a light transmissive pane located at least partially across the opening and defining a support surface; and, a light source located inside the enclosure for generating light to be transmitted through the light transmissive pane. A sterilizable light transmissive surgical instrument support may be also provided to be disposed over at least a portion of the light transmissive pane. Advantageously, with the subject invention, an assembly is provided which includes a sterilized surface for supporting surgical instruments which is backlit. With this arrangement, surgical instruments may be supported and illuminated from beneath to aid a medical practitioner in identifying the surgical instruments.

Abstract: A mask suitable for protecting the face of a patient during surgery comprises a transparent plastic shield which includes a transverse cutout that provides access to the nose and mouth, and a vertical gap which runs from the cutout to the shield's perimeter. Padding affixed to the perimeter of the shield's underside provides a cushion between the shield and face. The padding is preferably arranged such that the mask can be installed or removed without dislodging tubing inserted into the patient's nose or mouth via the transverse cutout. An attachment mechanism secures the shield to the face. A warming hood may be coupled to the protective mask. The hood preferably comprises outer and inner layers, with an access point at which air can be introduced between the layers; perforations on the inner layer permit warm air to be dispersed onto the patient.

Abstract: One aspect of the present disclosure relates to a stereotactic guide assembly comprising an implantable body and a fastener. The implantable body can have an interior chamber and a first passageway that extends through the implantable body into communication with the interior chamber. At least a portion of the interior chamber can be defined by a first coupling feature. The fastener can be configured to fit in the interior chamber. The fastener can have a second passageway extending therethrough, and a second coupling feature adapted to releasably engage the first coupling feature.

Abstract: A noninvasive stereotactic assembly for guiding an instrument to a target within a patient's head includes a head frame subassembly and an instrument positioning subassembly. The head frame subassembly is secured to a skull in the patient's head to determine an X-axis and a Y-axis of a three-dimensional coordinate system. According to the coordinate of the target in the three-dimensional coordinate system, ring members, a movable bracket, a swivel member, and an instrument holder of the instrument positioning subassembly are displaced by predetermined angles to guide the instrument toward the target.

Abstract: A trajectory frame for use with surgical navigation systems includes a base having a patient access aperture formed therein. A yoke is mounted to the base and is rotatable about a roll axis. A platform is mounted to the yoke and is rotatable about a pitch axis. An elongated guide is secured to the platform and includes opposite proximal and distal end portions and a bore that extends from the proximal end portion to the distal end portion. The guide is configured to removably receive various devices therein for quick release therefrom, including an optical tracking probe (which may be a universal tracker) detectable by a camera-based tracking system or an EM probe detectable by an EM navigation system, a microelectrode probe driver adapter, a drill guide and drill bit, skull fixation device and driver, and a catheter guide.

Abstract: The present invention provides digitally driven methods to conveniently and efficiently monitor and evaluate the positions of a patient's teeth during the course of orthodontic treatment. In an exemplary embodiment, an initial set of 3D digital data representing a patient's dental structure is provided by means of an X-ray radiograph and/or an intraoral scan. Then during the course of treatment, a reduced image representing part of the dental structure may be quickly provided using a bite plate or a low resolution intraoral scan. A three-dimensional (3D) image of the full dental structure is subsequently rendered or ‘reconstructed’ by registering elements of the initial image with corresponding elements of the reduced image. By reconstructing the dental structure from the reduced image, the treating professional can provide a precise, manipulable 3D image of the patient's complete dental structure for diagnostic and treatment planning purposes.

Abstract: Orthodontic systems and related methods are disclosed for designing and providing improved or more effective tooth moving systems for eliciting a desired tooth movement and/or repositioning teeth into a desired arrangement. Methods and orthodontic systems of the invention include tooth attachments having improved or optimized parameters selected or modified for more optimal and/or effective application of forces for a desired/selected orthodontic movement. Attachments of the present invention can be customized to a particular patient (e.g., patient-customized), a particular movement, and/or a sub-group or sub-set of patients, and configured to engage an orthodontic tooth positioning appliance worn by a patient, where engagement between the attachment and orthodontic appliance results in application of a repositioning force or series/system of forces to the tooth having the attachment and will generally elicit a tooth movement.

Abstract: A dental tool for removing a dental aligner secured to teeth may include a first contact point that is configured to contact a biting surface of the aligner; a second contact point that is configured to contact a gumline end of the aligner; and a third contact point that is configured to contact a lateral surface of the aligner. A method of using the dental tool to remove the dental aligner from teeth is also disclosed.

Abstract: Orthodontic appliances and related methods are provided, including a fast-dissolving and humidity-resistant coating, containing a colorant and a binder selected from a polyamide, cellulose derivative, or homopolymer/copolymer of poly(ethylene oxide). The coating can facilitate appliance identification and serve as a reference marking to assist the practitioner in appliance placement. Advantageously, the composition of these coatings allows the color marking to be rinsed off quickly, and yet the color of the coating does not bleed during storage even in high humidity environments. The fast-dissolving nature of these coatings also allows the coating to be deposited in concave and recessed areas of the appliance, such as the archwire slot and vertical slot, since these coatings can be removed prior to archwire installation.

Abstract: A dental implant includes a screw body and screw threads. The screw body has an apical end and a coronal end. Screw threads include a primary thread and a secondary thread, which overlap in at least a portion of the screw thread. Thread depth progressively increases from the coronal end to the apical end. The coronal end may contain any suitable secondary characteristics, such as machined threads, grooves, micro-threads, or any other characteristics favorable to successful outcomes with dental implant treatment. A method of making such a dental implant is also disclosed.

Abstract: The disclosure relates, in some embodiments, to a bone foundation guide configured to guide alteration of an alveolar ridge. A bone foundation guide may include a body with (a) a first end of a buccal wall and a first end of a lingual wall each connected to a first end of the body and (b) a second end of the buccal wall and a second end of the lingual wall each connected to a second end of the body such that the buccal wall is substantially parallel to the lingual wall and a space between the buccal wall and the lingual wall defines an open surgical space. A body may be configured to sit adjacent to a tissue spacing gasket having a thickness equivalent to a gum tissue that would normally cover the bone segment.

Abstract: A method of placing a dental implant analog in a physical model for use in creating a dental prosthesis is provided. The physical model, which is usually based on an impression of the patient's mouth or a scan of the patient's mouth, is prepared. The model is scanned. A three-dimensional computer model of the physical model is created and is used to develop the location of the dental implant. A robot then modifies the physical model to create an opening for the implant analog. The robot then places the implant analog within the opening at the location dictated by the three-dimensional computer model.

Abstract: A retractor for periodontal surgery includes an elongated handle from which extends a first connection portion and a second connection portion, with a blade extending from the second connection portion. The handle and the first connection portion are positioned at a first angle, the first connection portion and the second connection portion are positioned at a second angle. The first and second connection portions are generally co-planar. The blade is obliquely positioned at a third angle relative to the central axis of the second connection portion. The blade may be easily inserted into an incision in a patient's gum so as to retract the incision.

Abstract: The invention relates to a method for constructing tooth surfaces of a dental prosthesis and for producing dental restorations, starting from a 3D data record of an upper mandible layout and a 3D data record of a lower mandible layout, each layout comprising a number of teeth arranged in each mandibular arch and the teeth of the upper mandible layout and the teeth of the lower mandible layout at intercuspation making contact with each other at multiple contact points. The contact surfaces are selected by approximation. Relevant surface pairs lying opposite one another are identified and are incorporated by an optimization algorithm into local minimum distances, taking into consideration surfaces that can slide past one another. This allows the desired contact points to be produced. Surfaces that have not been selected are not considered in the production of the points of contact.

Abstract: A denture-securing device is provided that is usable to substantially secure a denture within a mouth. The denture-securing device may be used with top dentures, bottom dentures, or other configurations of dentures. The denture-securing device may advantageously secure dentures without requiring use of adhesives. The denture-securing device may also reduce the likelihood of food getting under dentures, provide a firm yet soft and comfortable fit, and minimize rocking of lower dentures. The denture-securing device may advantageously be secured to gums using a suction fit through saliva or other sources of moisture.

Abstract: The object of the invention is a brush head for an electric toothbrush, the brush head comprising a hollow body part (1), a back and forth rotating shaft (3) inside the body part (1), and a rotating bristle carrier (7) rotated back and forth by the shaft (3) at the first end of the body part (1), and where the second end of the shaft (3) comprises a protrusion (3a) that is in an inclined angle (A) in relation to the rotation axis of the shaft (3). The inclination angle (A) is substantially between 20-70 degrees, and the inclination of the protrusion (3a) is directed towards the rotation axis of the shaft (3).

Abstract: Packaged orthodontic assemblies include a chamber, an orthodontic appliance, and a support structure engaged with the appliance to secure the appliance in the chamber. The support structure can include a post complemental to a partially enclosed passage, typically an arch wire slot, in the appliance body. The support may orient the wall sections of the enclosed passage at an acute angle relative to a chamber side wall.

Abstract: A method for precisely identifying a fixed point of reference on a human jaw including providing a mandibular c-clamp, which has a shaft, an upper prong fixedly connected to the shaft, a lower prong movable along the shaft, and a wedge configured to selectively secure the lower prong to the shaft. The upper prong of the mandibular c-clamp is inserted into a patient's mouth. The lower prong of the mandibular c-clamp is then moved along the shaft to close on a patient's chin compressing patient's soft tissue, and a position of the lower prong is secured on the shaft using the wedge so that the lower prong is no longer movable along the shaft. A sensor is then secured to a designated area of the mandibular c-clamp so as to provide a reference point.

Abstract: Method of treating oral subgingival biofilms having obligate anaerobes, facultative anaerobes, aerobic bacteria and other micro-organisms (collectively oral pathogens) associated with certain systemic diseases present within a subgingival biofilm having proteins and amino acids, the steps including providing a periodontal medicament delivery tray having a seal against a patient's adjacent gums containing the oral biofilms with the systemic disease, said seal formed so as to have no contact with teeth, applying to the gingival tissue (sulcus or periodontal pocket) a biofilm penetrating antimicrobial agent, removing the imbedded oral pathogens from the gingival tissue following at least one applying of the antimicrobial agent to the gingival tissue; repeatedly administering colloidal hydrogen peroxide gel to the gingival tissue following the removing; and following each administering cleaning the gingival tissue with a cleaning agent directly following the administering of the colloidal hydrogen peroxide gel fo

Abstract: An oral care device such as an oral care implement or a toothbrush. The oral care device may include a handle and a head. The head may have a plurality of cleaning elements extending therefrom. The head may comprise an open space or cavity. A plurality of electrodes may be located within the open space or cavity. The electrodes may be coupled to a voltage source. The electrodes may be used to generate a chemical agent via the application of an electrical potential across the electrodes when in communication with an electrolyte. The chemical agents may include ozone, hydrogen peroxide, peroxide, chlorine hypochlorite, ions, peroxides, and/or other chemical agents.

Abstract: A cuff for use an as artificial sphincter includes an inflatable chamber and a backing. The inflatable chamber includes opposing inside and outside surfaces and inflated and deflated states. The backing is adjacent the outside surface of the chamber. The inside surface of the chamber includes two or more grooves that define the location of fold lines of the inflatable chamber when the inflatable chamber is in the inflated state. The inflatable chamber and backing are configured to surround a duct of a patient with the inside surface of the chamber facing the duct and the grooves extending substantially parallel to the duct.

Abstract: Methods, systems, and compositions for treatment are provided. The methods can be used to stretch and completely or nearly completely wrap a composition around an implant or tissue expander. The systems can be used to protect an implant or tissue expander by completely or nearly completely wrapping a composition around the implant or tissue expander. The compositions can be used to completely or nearly completely wrap around an implant or tissue expander to provide support and protection to the implant or tissue expander.

Abstract: Methods for delivering a sheet-like implant to a target site including a means of deploying and orienting the sheet-like implant within the body.

Abstract: A filter device has a catheter having a lumen, a shaft extended in the longitudinal direction from the lumen, and a filter capturing an embolus. The filter is connected to the shaft through a slide ring at the distal end thereof. The shaft is inserted into and passed through the ring. The ring is rotatable with respect to the shaft and slidable in the longitudinal direction. When the filter is expanded in a blood vessel, the ring slides on the shaft. The filter is connected to the shaft through another ring on the peripheral edge of an opening. The shaft is inserted into and passed through the ring. The ring is rotatable with respect to the shaft. The ring is held between a pair of stoppers fixed onto the shaft. Therefore, the movement of the ring in the longitudinal direction with respect to the shaft is prevented.

Abstract: Methods and apparatus for use in capturing embolic debris during a surgical procedure in a patient are provided. The methods include utilizing an embolic capture device that is configured for delivery into a patient via a transapical delivery approach and via an arterial delivery approach, and determining which of a transapical delivery approach and an arterial delivery approach should be used with the patient. The methods also include inserting the embolic capture device within a delivery system, and deploying the embolic capture device at a desired location within the patient's blood vessel that is downstream from the location of the surgical procedure. The same embolic capture device is configured for use with a transapical delivery approach and an arterial, such as a transfermoral, delivery approach.

Abstract: Devices and methods for providing protection from embolisms and microembolisms in a subject undergoing catheter-based intravascular procedures. The embolic protection devices have an expandable support frame comprising u-shaped members and leg members which facilitate proper placements in a defective valve annulus. The filtering devices expand in the vessels and allow blood flow to continue through the vessels, thereby catching and removing debris of the flowing blood. Also disclosed are embolic protection devices for use with a sutureless valve prosthesis which is implanted via catheter-based methods.

Abstract: The described invention provides several aspects designed to help mechanically break up a clot inside vessels and/or remove a clot via aspiration simultaneously, and a method of using same. According to some embodiments, the devices are adapted to irrigate a blood vessel during thrombectomy; to macerate an obstruction during thrombectomy, to block blood flow in a blood vessel during aspiration of a thrombus; or to capture and remove distal emboli. With the described invention, when used to ameliorate arterial clots, irrigation and aspiration are performed simultaneously in conjunction with a balloon or occlusive catheter to reverse flow of the vessel. With the described invention, when used to ameliorate venous clots and most arteriovenous dialysis grafts, a filter-tipped aspirator is used downstream from the clot to capture and remove dislocated emboli. An optional embodiment protects the three Great Vessels of the heart, unlike the prior art.

Abstract: A valve comprising: (a) a rod, (b) a plurality of struts in communication with the rod and extending generally radially outward away from the rod in a deployed state, the plurality of struts including at least: (i) a plurality of first struts that extend radially outward from the rod a first distance, and (ii) a plurality of second struts that extend radially outward a second distance from the rod, wherein the second distance is less than the first distance; and (c) one or more membranes that are in communication with the first struts, the second struts, or both.