Abstract: Glue Grease, has been designed and made as a lubricant to be used in moving mechanical parts in difficult environmental conditions as an anti-abrasion material in order to increase the longevity of parts prone to friction.

Abstract: This invention relates to methods of lubrication for biological tissue, especially joint and cartilage surfaces, and to methods of treating osteoarthritis using high molecular weight, hydrophilic polymer brushes, which mimic the structure and activity of lubricin. These synthetic lubricin analog polymer brushes (termed herein graft brush polymers), include poly(acrylic acid) backbones grafted with polyethylene glycol.

Abstract: Provided herein is a composition for improving performance of waxless skis, in particular skin skis, more particularly of skin strips, on snow, the composition com¬prising (a) C1-6-alcohol(s); and (b) lubricant(s) selected from a group consisting of (c) perfluoropolyethers, (d) polydi(C1-3-alkyl)siloxanes, and mixtures thereof.

Abstract: A lithium-based thickener is contained in an amount of 6 to 14 wt % based on a total weight of a grease composition. The amount of the lithium-based thickener contained in the grease composition can be reduced by about half compared to a conventional thickener, thus effectively increasing viscosity of base oil and reducing fluidity.

Abstract: The present invention, in one aspect, provides a refrigerating machine oil including a lubricating base oil and a compound represented by the following formula (A): wherein R1 and R2 each independently represent a monovalent hydrocarbon group, and R3 and R4 each independently represent a hydrogen atom or an alkyl group, the refrigerating machine oil being used with a refrigerant including an unsaturated hydrofluorocarbon.

Abstract: Lubricant composition formulations comprising at least one biodegradable plastic, such as polyhydroxyalkanoate and/or polybutylene succinate, and at least one lubricant, such as a vegetable oil.

Abstract: Disclosed are lubricant compositions with improved oxidation stability which are prepared with Group III base stocks comprising greater than or equal to about 90 wt. % saturated hydrocarbons (saturates); a viscosity index from 120 to 145; a unique ratio of molecules with multi-ring naphthenes to single ring naphthenes (2R+N/1RN); a unique ratio of branched carbons to straight chain (BC/SC) carbons; and a unique ratio of branched carbons to terminal chain (BC/TC) carbons.

Abstract: A manual transmission oil composition includes: polyisobutenyl succinimide serving as a detergent-dispersant; and comb polymethacrylate (comb PMA), which has at least one of polar and nonpolar branches connected to a main chain thereof, and serves as a viscosity modifier. Polyisobutenyl succinimide is contained in an amount of 1 wt % to 5 wt % based on a total weight of the manual transmission oil composition, W and comb PMA is contained in an amount of 4 wt % to 12 wt % based on the total weight of the manual transmission oil composition.

Abstract: Disclosed are lubricant compositions prepared with Group III base stocks comprising greater than or equal to about 90 wt. % saturated hydrocarbons (saturates); a viscosity index from 120 to 145; a unique ratio of molecules with multi-ring naphthenes to single ring naphthenes (2R+N/1RN); and a unique ratio of branched carbons to straight chain (BC/SC) carbons; a unique ratio of branched carbons to terminal carbons (BC/TC); and unique MRV behavior as a function of base stock naphthene ratio (2R+N/1RN).

Abstract: The present invention relates to extracted plant lipid or microbial lipid comprising docosapentaenoic acid, and processes for producing the extracted lipid.

Abstract: Disclosed here are methods and apparati for making a desired scent, smell, odor, aroma, and/or taste. Also disclosed herein are methods and apparati for making a scent, smell, odor, aroma, and/or taste that will produce a desired response in a desired group of subjects.

Abstract: Disclosed here are methods and apparati for making a desired scent, smell, odor, aroma, and/or taste. Also disclosed herein are methods and apparati for making a scent, smell, odor, aroma, and/or taste that will produce a desired response in a desired group of subjects.

Abstract: According to the invention, the compositions and methods provide for the complete removal of labels, synthetic glues and/or adhesives from a plurality of surfaces through the use of an aqueous or non-aqueous basic organic solvent and/or an amidine, optionally in combination with surfactants, chelants, acidulants and/or additional bottle wash additives. Beneficially, the compositions and methods are suitable for use at lower temperatures and pH conditions, along with under caustic-free and/or reduced caustic conditions to effectively remove such labels, synthetic glues and/or adhesives from a surface within less than about 30 minutes.

Abstract: A detergent pack comprising a plurality of water-soluble unit-dose detergent products the products comprising a detergent composition and an enveloping material the detergent composition comprising: a) a malodour-generating amine-containing cleaning active; and b) a malodour reducing agent comprising a carboxylic functionality. wherein the composition comprises from about 15% to 50% of amine-containing cleaning active.

Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

Abstract: The present invention relates to a composition comprising: (a) at least one surfactant, at least one surfactant system, at least one soap, or any mixtures thereof; and (b) a polypeptide having lipase activity selected from the group consisting of: (I) a polypeptide having at least 80% sequence identity to the mature polypeptide of SEQ ID NO: 2; (II) a polypeptide encoded by a polynucleotide that hybridizes under low stringency conditions with (i) the mature polypeptide coding sequence of SEQ ID NO: 1, or (ii) the full-length complement of (i); (III) a polypeptide encoded by a polynucleotide having at least 80% sequence identity to the matore polypeptide coding sequence of SEQ ID NO: 1; (IV) a variant of the mature polypeptide of SEQ ID NO: 2 comprising a substitution, deletion, and/or insertion at one or more positions; and (V) a fragment of the polypeptide of (I), (II), (III), or (IV); wherein said composition is a cleaning and/or treatment composition.

Abstract: A laundry care composition including: (a) at least one laundry care ingredient and (b) a leuco composition. The laundry care composition has a ?HA of less than or equal to 40. Methods of treating textiles with such laundry care compositions.

Abstract: A treatment liquid is a treatment liquid for a semiconductor device, which contains a fluorine-containing compound and a water-soluble aromatic compound not having a heterocyclic group but having a benzene ring, and has a pH of 5 or less.

Abstract: Provided herein is a composition for cleaning skin strips of skin skis, in particular for removing hydrophobic compounds, such as oils, resins, grease, and/or waxes, from the surface of the skin strips. The composition comprises (a) C1-6-alcohol; (b) at least 10% by weight of the total weight of the composition of dibasic ester(s) of formula R1O—C(O)—(CH2)n—C(O)—OR1, wherein n is 2 to 4; and each R1 is independently C1-6-alkyl, (c) 0 to 5% by weight of the total weight of the composition of alkoxyalkanol(s) of formula R2O—(CH2)m—OH wherein m is 1 to 4, preferably 2 or 3, and R2 is C1-6-alkyl, preferably C3-6-alkyl; and (d) 0 to 5% by weight of the total weight of the composition of tri(C1-6-alkanol) amine(s).

Abstract: A cleaning product including a spray dispenser and a cleaning composition suitable for spraying and foaming, the composition housed in the spray dispenser wherein the composition includes: i) from about 5 to about 15% by weight of the composition of a surfactant system; and ii) a glycol ether solvent selected from the group consisting of glycol ethers of Formula I: R1O(R2O)nR3, Formula II: R4O(R5O)nR6 and mixtures thereof wherein R1 is a linear or branched C4, C5 or C6 alkyl or a substituted or unsubstituted phenyl, R2 is ethyl or isopropyl, R3 is hydrogen or methyl and n is 1, 2 or 3 R4 is n-propyl or isopropyl, R5 is isopropyl, R6 is hydrogen or methyl and n is 1, 2 or 3 and and a specific cyclic diamine

Abstract: A method of creating a protective coating on an alkali metal hydroxide-containing solid is provided. The method includes providing carbon dioxide to an alkali metal hydroxide-containing solid and allowing the alkali metal hydroxide and carbon dioxide to react thereby forming a carbonate or bicarbonate-containing layer on the exterior of the solid wherein the carbonate or bicarbonate-containing layer is non-hygroscopic and water soluble, and wherein greater than 80% of the hydroxide in the hydroxide-containing solid does not react with the carbon dioxide, and further wherein the alkali metal hydroxide-containing solid is substantially free of lithium hydroxide. A method of testing for the presence of carbonate-containing coating on an alkali metal hydroxide containing solid is also provided. The method includes exposing the coated solid to 95 weight percent ethanol, collecting the ethanol effluent and testing the effluent for alkali metal hydroxide.

Abstract: The present invention describes a detergent composition in the form of a flexible sheet, which in turn is soluble in water, and the water-soluble detergent sheet. Said detergent composition in the form of a flexible sheet comprises a unique mixture of components, including: a water-soluble polymeric component, an anionic surfactant, a non-ionic surfactant, water and other components. Once mixed in the appropriate proportions, the components produce a flexible sheet with detergent characteristics that can be incorporated directly into a clothes-washing recipient, said recipient ranging from a simple bowl to an advanced automatic washing machine. Once the detergent sheet comes into contact with water inside the washing recipient, the sheet dissolves and releases the active ingredients and complementary ingredients contained therein.

Abstract: An enriched trichome pellet product including either a hop derived lupulin component or a cannabis derived trichome component, and the associated cryogenic and mechanical method for the efficient production of the pellet product. The pellet is produced at low temperatures, which aids in pellet production eliminating degradation of the hop lupulin having a high alpha acid and essential oils content that is especially suited for use in the brewing of beer and hop flavored beverages, and aids in eliminating degradation of the cannabis trichome having aromatic oils, and terpenoids and terpenes as well as therapeutic and psychoactive cannabinoids including THC, CBG, and CBD that is especially suited for use in cannabis component or “cannabinoid” enriched products.

Abstract: A system and method for the purification of beverage fluids, primarily alcohol beverages, based on the action of hydrodynamic cavitation processing of microbiological and chemical contaminants, micro particles and colloidal particles. The system is a batch system with a single vessel having an extraction tube and discharge tube extending into the same reservoir of fluid. Fluid is drawn through the extraction tube and forced through the discharge tube. The discharge tube contains cavitation elements dispersed along its length to generate hydrodynamic cavitation in the fluid as it is pumped through. The discharge fluid is mixed with the fluid already in the vessel and is re-drawn through the extraction tube in continuous batch processing.

Abstract: This invention relates to a floating horizontal tubular photobioreactor system comprising a photosynthetically active area made of flexible tubes connected to rigid manifolds with an integrated system for mixing, aeration and degassing. This invention further relates to methods of using the floating photobioreactor system.

Abstract: Various implementations include a competitive assay platform with a partitioning device disposed in a well. The well has a bottom surface, a central axis, and a side surface. The partitioning device includes a first wall portion, a second wall portion, and a third wall portion. Each wall portion has an upper edge, a lower edge, a first side edge, a second side edge, and first and second divider surfaces. The lower edge of the first wall portion, second wall portion, and third wall portion of the partitioning device disposed on the bottom surface of the well, and the first side edges of the first, second, and third wall portions are disposed against the side surface of the well, defining first, second, and third compartments.

Abstract: The invention discloses a hollow profile wall segment (1) for a bioreactor or mixer support vessel (2;2a;2b), comprising a base profile (3) with two parallel wide sides (4,5), two narrow sides (6,7) and at least one heat exchange channel (8) extending in a longitudinal direction of the base profile through an interior space (9) in the base profile, wherein the hollow profile wall segment is adapted to be joined with similar hollow profile wall segments to form a side wall (12) of a bioreactor or mixer support vessel (2) and wherein each narrow side comprises at least one coupling member (10,11;11a;150) capable of securing the hollow profile wall segment side by side with similar hollow profile wall segments.

Abstract: A polygonal scaffold includes at least three polyproline II (PPII) helix rods and at least three connectors. Each of the PPII helix rods is composed of a plurality of repeat units represented by Formula (i), and at least one of the PPII helix rods has at least one of hydrogen atoms of at least one of the repeat units being substituted by a first chemical handle for connecting a ligand. Each of the connectors is a divalent organic group, and every two of the PPII helix rods are connected by one of the connectors to form a closed ring.

Abstract: Provided are a support for culturing cells, a method of preparing the support, and a method of culturing cells using the support. When the support and the methods are used, an adherence rate, a surface area, and a proliferation rate of cells may improve, and detachment of the cells may be facilitated, thereby increasing a cell recovery rate. In addition, a physiologically active substance may be slowly released, thereby reducing the cost for a cell culture process.

Abstract: A method and system of and for handling, preserving, separating, filtering, collecting, manipulating, and/or culturing ex vivo biological material including red blood cells, white blood cells, and blood plasma within a bioreactor having a gas permeable membrane that allows for passive ventilation.

Abstract: According to an aspect of the invention, an observation system includes at least one observation apparatus and a thermostatic bath. The observation apparatus includes an imaging unit, a temperature sensor, and first control circuitry. The imaging unit captures an image of the sample. The temperature sensor measures an internal temperature of the observation apparatus. The first control circuitry estimates a sample temperature based on the internal temperature and calculates an indication temperature based on the sample temperature and temperature distribution data of the thermostatic chamber. The thermostatic bath includes a memory and second control circuitry. The memory stores the temperature distribution data. The second control circuitry performs the temperature control by setting a set temperature based on the indication temperature.

Abstract: An integrated system of cell culture and operation and a method for controlling the same. The integrated system of cell culture and operation includes a housing, a front side of the housing being provided with operating gloves. The housing has a double-layer structure consisting of an inner layer and an outer layer. An upper wall and a lower wall of the inner layer are both provided with through holes. The outer layer has a gas inlet, a gas outlet and a humidifying port. The integrated system of cell culture and operation further includes: a heating module arranged in an interlayer, and a transport module configured to transport gas and circulate the gas in the inner layer and the interlayer, resulting in low gas consumption.

Abstract: A self-contained anaerobic environment-generating culture device is provided. The culture device includes a first substrate having opposing inner and outer surfaces, a second substrate having opposing inner and outer surfaces, a growth region disposed between the inner surfaces of the first and second substrates, an effective amount of a substantially dry enzyme component of an enzyme-mediated oxygen depletion system, an effective amount of a substantially dry enzyme substrate component of the enzyme-mediated oxygen depletion system, and a dry, cold-water-soluble gelling agent disposed in the growth region. The enzyme and enzyme substrate components are disposed in coatings in the growth region. The first and second substrates are substantially nontransmissible to gaseous oxygen. Methods of making and using the culture device area also provided.

Abstract: System, including methods and apparatus, for identifying and picking spectrally distinct colonies. In an exemplary method, a filter may be received in an optical path extending from a light source to a grayscale image detector. The filter may be configured to increase an intensity difference between a first type of colony and a spectrally distinct second type of colony. Colonies including both types may be received in the optical path. An image of the colonies may be obtained with the grayscale image detector. At least one of the types of colony may be identified in the image. One or more colonies of the at least one type may be picked robotically.

Abstract: There is provided a device comprising at least the followings: a hollow fiber type separator for separating a liquid A from a suspension comprising an inlet and outlet for passing the suspension, which communicate with the inside of hollow fibers, and at least one discharge port for discharging the separated liquid A, which communicates with the outside of the hollow fibers; an aseptic connection connector for aseptically connecting a bag containing the suspension in a non-aseptic environment, which is connected to the inlet of the hollow fiber type separator; a drainage bag for storing the separated liquid A, which is connected to the discharge port of the hollow fiber type separator; and a collection bag for storing a suspensoid from which the liquid A has been separated, which is connected to the inlet or outlet of the hollow fiber type separator.

Abstract: The present invention provides a method for culturing photosynthetic microalgae with which xanthophyll can be obtained more efficiently than before. The culture method of the present invention comprises a step of performing light irradiation of encysted photosynthetic microalgae containing xanthophyll in an amount of 3 to 9% by mass in terms of a dry mass. Preferably, in the step of performing light irradiation, the xanthophyll content in photosynthetic microalgae is kept at 2% by mass or more in terms of a dry mass. Preferably, the step of performing light irradiation includes step (A) of increasing the number of cells in which light irradiation (a) is performed; and step (B) of increasing the xanthophyll content in photosynthetic microalgae in which light irradiation (b) of the photosynthetic microalgae subjected to the step (A) of increasing the number of cells is performed.

Abstract: The present disclosure describes methods for generating microbial strains expressing a heterologous bacterial hemoglobin gene that produce biomolecules of interest. In aspects, the disclosure provides novel bacterial strains, which express a heterologous bacterial hemoglobin gene whose expression is controlled by a native Corynebacterium glutamicum promoter or a mutant promoter derived therefrom. Also provided herein are methods for producing a library of bacterial hemoglobin genes using a promoter ladder comprising a plurality of promoters derived from Corynebacterium glutamicum.

Abstract: The invention generally relates to the cultivation and growth of bacterial, fungal and yeast cells on pilot plant and industrial scales and, more particularly, to the cultivation and growth of microbial cells in/on hydrophilic particles containing pre-seeded nutrient media within a matrix of hydrophobic sand.

Abstract: Methods for evolving cells or strains towards improved methyltransferase activity, particularly SAM-dependent methyltransferase activity, as well as to cells and strains useful in such methods and methods of using the evolved cells in the production of methylated products.

Abstract: The present disclosure pertains to a mammalian cell culture genetically modified to express, and which expresses, a neublastin antibody polypeptide, or fragment thereof, in the culture, and to a neublastin antibody polypeptide, or fragment thereof, made by a mammalian cell culture genetically modified to express, and which expresses, the neublastin antibody polypeptide, or fragment thereof.

Abstract: The present invention relates to Nelumbo nucifera callus having an increased content of gallic acid or an extract thereof and to a method for preparing the same. The Nelumbo nucifera callus extract according to the present invention has an excellent whitening effect by containing a large amount of gallic acid, and thus can be advantageously used as a cosmetic composition.

Abstract: Provided herein, in some embodiments, are methods comprising culturing human brain tissue spheroids on a three-dimensional scaffold in culture media comprising vascular endothelial growth factor (VEGF), and producing a population of cells, wherein cells of the population are positive for nestin, glial fibrillary acidic protein (GFAP), and/or vimentin.

Abstract: The present disclosure relates to an in-vitro method for identifying and analyzing secretion proteins, in which a three-dimensional sweat gland equivalent having from about 500 to about 500,000 sweat gland cells and a diameter of from about 100 to about 6,000 ?m is firstly provided and then any secretion proteins present in this equivalent are infected and analyzed. In a further method step c) the influence of test substances on the proteins identified previously in step b) is examined. Since the three-dimensional sweat gland equivalents used in step a) comprise differently differentiated cells and portray the in-vivo situation well, the measurement data obtained with the in-vitro method as contemplated herein can be transferred well to the in-vivo situation.

Abstract: Described here are systems and methods for deriving both spinal motor neurons and brain microvascular endothelial cells from induced pluripotent stem cells using distinct methods and combining them in a chip format. Neurons cultured alone in chip microvolume displayed increased calcium transient function and chip-specific gene expression. When seeded with endothelial cells, interaction further enhanced neural function, elicited vascular-neural interaction, niche gene expression with enhanced in vivo-like signatures arising from the chip co-cultures. Development of novel media formulations further allow for improved readout of differentiation process, by eliminating additives that otherwise confound differentiation processes and resulting phenotypes.

Abstract: The problem is to produce functional liver cells usable in testing the metabolism and toxicity of a drug, from pluripotent stem cells. The solution includes a method for producing highly functional liver cells using pluripotent stem cells, comprising, from pluripotent stem cells, acquiring primitive endoderm derived from the pluripotent stem cells by a process involving steps (A) and (B), from the primitive endoderm, acquiring liver precursor cells by a process involving step (C), and, from the liver precursor cells, acquiring the highly functional liver cells by a process involving step (D): (A) culturing under serum-free and feeder-free conditions; (B) culturing in the presence of albumin and at least one kind of cytokine; (C) culturing in the presence of SHH or an SHH agonist and at least one kind of cytokine; and (D) culturing and maturing in the presence of at least one kind of cytokine.

Abstract: The invention described herein relates to methods of isolating non-embryonic stem cell, e.g., adult stem cell, from a non-embryonic tissue, e.g., an adult tissue or organ. Non-embryonic stem cells (e.g., adult stem cells) thus isolated from the various tissues or organs can self-renew or propagate indefinitely in vitro, are multipotent and can differentiate into the various differentiated cell types normally found within the tissue or organ from which the stem cells are isolated. In addition, the isolated stem cells can be propagated through clonal expansion of a single isolated stem cell, to produce a clone of which at least about 40%, 70%, or 90% or more cells within the clone can be further passaged as single cell originated clones.

Abstract: The present invention relates to directed differentiation and maturation of hepatocyte-like cells. In particular, the present invention relates to exposure of hepatocyte-like cells to an activator of a retinoic acid responsive receptor, such as retinoic acid (RA), optionally in combination with an inhibitor of GSK-3 (Glycogen synthase kinase 3) or activator of Wnt signalling and/or with the overlay of the cells with one or more components characteristic of the mammalian extracellular matrix (matrix overlay). The present invention also relates to exposure of hepatocyte-like cells to an activator of a retinoic acid responsive receptor, such as retinoic acid (RA), optionally in combination with an inhibitor of a cycline dependent kinase (CDK) and/or with the overlay of the cells with one or more components characteristic of the mammalian extracellular matrix (matrix overlay).

Abstract: The invention relates, in part, to methods to deliver molecules into in vitro and in vivo cells and into organisms using exogenous and/or endogenous membrane proteins.

Abstract: The present invention relates to: a method for producing a spheroid form of tonsil-derived stem cells, the method enhancing growth and differentiation efficiency of tonsil-derived stem cells; and a method for producing a spheroid form of parathyroid hormones from the same. The method of the present invention for producing a spheroid form of tonsil-derived stem cells cultures the tonsil-derived stem cells in the form of a spheroid to thereby enhance the proliferation rate of the stem cells per se and remarkably increase differentiation potency into parathyroid cells. Thereby, the method has a remarkable effect on the growth and differentiation of the tonsil-derived stem cells into parathyroid cells, etc.

Abstract: The present invention relates to: a cell therapeutic agent including ventral midbrain-derived astrocytes and dopamine neural progenitor cells; a method of treating a neurodegenerative disorder including administering a pharmaceutical composition comprising ventral midbrain-derived astrocytes and dopamine neural progenitor cells into a subject; and a method for differentiation into dopamine neurons, which includes preparing a mixture of ventral midbrain-derived astrocytes and dopamine neural progenitor cells and co-culturing or co-grafting the mixture. The co-grafting of ventral midbrain-derived astrocytes and dopamine neural progenitor cells (neural stem cells) improves the survival and differentiation of dopamine neurons and thus dramatically improves therapeutic outcomes in a neurodegenerative disorder including Parkinson's disease.