Abstract: An electronic device is coupled with a system and a device for controlling one or more components of a pool or a spa. The electronic device is substantially sealed from water and environmental intrusion to a desired protection level and located within a housing that is able to be coupled with a pool and/or a spa frame. A screen is able to display visual content based on content of the electronic device. The visual content is able to comprise song, album, and artist information and caller identification information of a call received by the electronic device. The system and device is usable to control one or more components of the pool and/or the spa.

Abstract: Spa systems may be used all year round and in colder weather provide an enjoyable experience for users through the cold ambient outdoor temperature and the heated water of the spa. However, failures in respect of the water circulating pump and/or heater of the spa system either mechanically, electrically or through overall power outages mean the water in the spa system and its pipework can easily freeze if ambient conditions are cold enough leading to cracks in the spa system or pipes and hence leaks when the water thaws requiring costly repair or replacement of components or entire systems. Accordingly, a freeze protection system is provided that uses a backup thermal management system discretely or in combination with other backup systems. These freeze protection systems offering backup when mechanical failures, electrical failures etc. arise by providing thermal input to the spa system through alternate thermal paths and providing alarms.

Abstract: The blister pack for medicinal products comprises a bottom film in which blister pockets are formed, which are surrounded by webs of the bottom film. The blister pockets comprise a two-level shape with a first recess and second recess situated lower down. A lidding film is sealed to the webs of the bottom film and to a strip of active material, which is arranged in each blister pocket. The medicinal product is accommodated in the second recess, and the strip of active material is accommodated in the first recess. The first recess comprises, in a bottom area thereof, a peripheral rib, which extends around the second recess, or at least two projecting knobs, which are arranged next to the second recess, wherein the strip of active material rests on the rib or on the knobs.

Abstract: The method for producing blister packs for medicinal products comprises the steps of forming blister pockets in a bottom film, wherein each blister pocket has an at least two-level shape with a first recess and a second, lower recess, filling the second recesses of the blister pockets with the medicinal products, placing a strip of active material in the first recess of each blister pocket above the medicinal product, wherein the strip of active material rests on at least one support surface of the first recess next to the second recess, sealing a lidding film to webs of the bottom film arranged around the blister pockets and simultaneously to the strips of active material, thus forming a sealed blister web, and stamping out individual blister packs from the blister web.

Abstract: Systems and containers for organizing and administering an oral immunotherapy regimen to a patient are disclosed herein. One aspect of the present technology is directed systems for efficiently and safely identifying pre-packaged dose units to administer to a patient undergoing oral immunotherapy. Further aspects of the present technology are directed to reducing medical staff dosing errors when administering an oral immunotherapy regimen. In one embodiment, the system includes a plurality of dosage containers, wherein each dosage container includes dosage identification characteristics corresponding to dosage of an oral immunotherapy composition. Further aspects of the present technology are directed to methods of dispensing an oral immunotherapy composition to a patient in a manner that mitigates the risk of errors in oral immunotherapy dose administration.

Abstract: A novel device, method and kit for reconstitution of a solid or semi-solid pharmaceutical composition by a negative pressure differential includes (i) a first adapter with a first connector, a first peripheral wall wherein the first adapter is coupled to the first vial by means of a first connector; (ii) a second adapter with a second connector, a second peripheral wall wherein the second adapter is coupled to the second vial by means of a second connector; (iii) a transfer port wherein the transfer port includes a first end ending in first adapter to gain access to first vial and a second end ending in second adapter to gain access to second vial; wherein the first adapters and the second adapter are joined together in vertical direction by means of horizontal wall; wherein the adapter connected to the vials by means of the ends.

Abstract: Disclosed is a system for administrating fluids to a patient, such as an infant. The system comprises a container that defines a drip chamber, a source of nutritive fluid fluidically communicating with the drip chamber, and a tube connecting the drip chamber to the gastric cavity of a patient, the chamber including a membrane that is gas-permeable but that is resistant to fluid passage. The system allows fluids to be introduced to the patient and for gastric gases to be released while they are resistant to the leak and spillage.

Abstract: An enteral dosing control coupling comprising a cylindrical collar defining a hollow internal chamber and a lumen extension tip projecting axially into the internal chamber, the lumen extension tip defining an internal lumen extending therethrough. In example forms, the lumen extension tip is integrally formed with the cylindrical collar. In other example forms, the lumen extension tip is a separate piece and is removably engageable within the cylindrical collar.

Abstract: An adjustable feeding tube holder. The adjustable feeding tube holder includes an elongated rod member having a clamp head affixed to one end and a connection member affixed to the second end. A second clamp member is disposed along, and slidably engaged to, the elongated rod member such that the second clamp member can be manually positioned along the rod member via a trigger handle. The clamp head and the second clamp member are configured to removably attached the device to a chose surface such as a wheelchair, bed rail, or table. The first connection member is rotatably connected to the elongated rod. A second connection member having a tube holder on an end thereon is rotatably and slidably connected to the first connection member. The tube holder configured to receive a feeding tube therein.

Abstract: An adaptive audio therapy system which detects and processes one or more individuals' conditions to provide adaptive, continuous audio therapy in real-time. The adaptive audio therapy system generally includes a detection device that is typically in physical contact with an individual, such as a pacifier or steering wheel. The detection device may include sensors to detect various conditions of the individual, such as heart rate, respiration rate, temperature, and the like. A computing device receives and processes the various conditions detected by the sensors. Based on the detected conditions, the computing device provides audio therapy which is adaptive to the condition of the patient and which is continuously adapted in real-time.

Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth include a carrier that remains stable and translucent during storage. The compositions include a carrier comprising a stable and translucent resin and a fluoride ion source (e.g., a fluoride salt such as sodium fluoride) dispersed within the carrier so as to provide biologically available fluoride ions to teeth being treated. The carrier resists formation of solids that can plug a 25 gauge (or 30 gauge) syringe brush applicator tip. The compositions may also include an adhesion promoting agent comprising an alkyl phosphoric acid. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.

Abstract: A dental adhesive curable composition containing a polymerizable monomer including a polymerizable monomer represented by formula (1?) and defined amounts of an acidic group-containing polymerizable monomer, a polymerization initiator containing a peroxide and a photopolymerization initiator, and a reductant containing a sulfinic acid compound and/or a salt thereof, and a filler: wherein the R groups, n and m are defined. A dental adhesive curable kit and a mobile tooth fixing material are also provided.

Abstract: A method of removing a dental adhesive may comprise locating the position of the dental adhesive, directing radiant energy into the dental adhesive causing the dental adhesive to weaken a bond formed with the dental adhesive, and breaking the bond by applying a suitable force to overcome the weakened bond. A dental adhesive may comprise a polymer and a dye or pigment. The dental adhesive may be formulated to cure to form a bond that is weakened in response to the dye or pigment absorbing radiant energy subsequent to curing.

Abstract: Cosmetic composition for cosmetic treatment of keratinous fibers, comprising: (a) from about 0.1 to about 5.0 wt % fibers (b) from about 5.0 to about 19 wt % ethanol (c) from about 78 to about 94 wt % propellant.

Abstract: Cosmetic stick containing: a) one or more UV filters, b) a Fischer-Tropsch wax with a solidification point of 80-85° C. (measured according to ASTM D 938) and a penetration at 25° C. of 0.4-0.9 mm (measured according to ASTM D 1321), the preparation being free from 3-(4-methylbenzylidene)-camphor, 2-hydroxy-4-methoxybenzophenone (INCI: Oxybenzone), 2-ethylhexyl 4-methoxycinnamate (INCI: Octyl Methoxycinnamate) and ethylhexyl-2-cyano-3,3-diphenylacrylate (INCI: Octocrylene).

Abstract: An antioxidant dispersion contains an oil component having a polyunsaturated fatty acid content of less than 50% by mass, a water-soluble antioxidant, at least one kind of compound selected from the group consisting of a polyhydric alcohol compound having 5 or less carbon atoms and reduced starch syrup, an emulsifier, and water. The emulsifier preferably contain a compound having an HLB value of 4.0 or less. In addition, in the antioxidant dispersion, a content of the emulsifier is preferably 0.5% by mass to 20% by mass with respect to a total mass of the antioxidant dispersion.

Abstract: Disclosed is a kit and method for whitening teeth and promoting better oral hygiene. A kit for one-step teeth whitening is disclosed in which concentrated hydrogen peroxide is delivered into the oral cavity by aerosol spray, without burning, discomfort or damage to the soft tissues of the mouth. Protocols are also disclosed in which an effervescent powder formulation is included as a post-treatment following the aerosol spray.

Abstract: The present invention relates to a composition in the form of an oil-in-water emulsion comprising one or more UV-screening agents, one or more anionic crosslinked hydrophilic polymers, one or more surfactants having an HLB less than or equal to 5 and one or more specific silicone copolymers. The present invention also relates to a cosmetic method for treating the skin against UV radiation using said composition.

Abstract: An oil-in-water emulsion cosmetic containing (A) to (E) as essential components and having a pH of 6 or less: (A) an L-ascorbyl tetra fatty acid ester derivative represented by the following general formula (I) Formula 1 wherein R represents a branched alkyl fatty acid residue having 8 to 18 carbons; (B) a polar oil which is liquid at 25° C. and having an IOB value of 0.1 to 0.5; (C) a chelating agent; (D) an antioxidant; and (E) water.

Abstract: The instant disclosure relates to methods for treating skin, for example, methods for desquamation of the skin of the face. The methods use a two-step process of first treating the skin with an alkaline composition having a pH of at least 8 followed by a second step of treating the skin with an acidic composition having a pH of 5 of less. The acidic composition includes one or more ?- and/or ?-hydroxy acids, which react with the skin to cause desquamation and stimulate new skin cell growth. Treating the skin with the claimed alkaline compositions improves the efficacy of the treatment with the acidic composition while reducing skin irritation and discomfort.

Abstract: Hair treatment agents and methods for treating hair are provided. An exemplary hair treatment agent includes, based on the weight of the hair treatment agent, from about 0.001 to about 20 wt. % of at least one alpha-substituted aldehyde, at least one bivalent or trivalent metal salt, and at least one organic acid.

Abstract: Hair treatment products comprising, in relation to its weight, from about 0.001 to about 20% by weight of at least one alpha-substituted aldehyde and from about 0.001 to about 20% by weight of at least one proteolipid of formula (II) R?—X—R?, in which R? represents a straight-chain or branched, saturated or unsaturated hydrocarbon radical having 11 to 24 carbon atoms, R? represents a protein, a peptide or a protein hydrolysate, X represents —C(O)O— or —N+(RIII2)—RIV— or —N(RIII)RIV— or —C(O)—N(RV)RV I—, RIII represents —(CH2)x—CH3 wherein x=0-22 and RIV represents —CH2—CH(OH)—CH2— or (CH2)x- wherein x=0-22; RV and RVI represent independently from each other —H or —(CH2)x—CH3 wherein x=0-22; with the proviso that R? represents keratin or a keratin hydrolysate if X represents —C(O)O—, which lead to improved structural reinforcement of keratin fibres and improved hair care, and which reduce or prevent colour washout in dyed hair.

Abstract: The present invention relates in general to methods of treating sweating disorders and in particular to topical compositions for the treatment of hyperhidrosis. The methods of the present invention relate to the topical application of a composition comprising a therapeutically effective amount of oxybutynin, tolterodine or a substituted benzamide such as sulpiride.

Abstract: A nail polish composition system includes (a) a base coat nail polish composition including organic solvents, film-forming compounds, plasticizers, and one or more additives; and (b) a top coat nail polish composition including a mixture of cyanoacrylates and a methacrylate. The base coat nail polish composition is applied to a fingernail to form a base coat film. Thereafter, the top coat nail polish composition is applied on or over the base coat film to form a top coat film. The nail polish composition system can significantly shorten the time required for drying the base and top coat nail polish compositions. In addition, the nail polish composition system may be applied without dipping the fingernail in powder glaze.

Abstract: A process for permanently reshaping keratin fibers comprising mixing a component A and a component B to form a reducing composition. The component A comprises at least one thiol-based reducing compound having one thiol group selected from the group consisting of thioglycolic acid and derivatives thereof, thiolactic acid and derivatives thereof, 3-mercaptopropionic acid and derivatives thereof, and cysteine and derivatives thereof, and has pH 7.0 or less and the component B comprises at least one buffer salt selected from the group consisting of carbonates, bicarbonates and carbamates, and has pH 8.0 or more, wherein at least one of the component A and component B comprises at least one disulfide compound that is further defined, and wherein the reducing composition has a pH ranging from 7.0 to 7.8 and a viscosity ranging from 500 cps to 100,000 cps. The reducing composition is then applied to the keratin fibers.

Abstract: A personal cleansing composition includes: (a) a surfactant system, wherein the surfactant system includes: from about 0.1% to about 5%, of a fatty acyl isethionate surfactant; from about 0.5% to about 40%, of a co-surfactant, wherein the co-surfactant is selected from the group consisting of an anionic surfactant being not an isethionate surfactant, a non-ionic surfactant, an amphoteric surfactant, a zwitterionic surfactant, and mixtures thereof; (b) from about 0.05% to about 5%, of a natural polysaccharide, a chemically modified natural polysaccharide, or a combination thereof; wherein the personal cleansing composition includes a first and second phase, wherein the first phase is an isotropic and micellar surfactant phase; wherein the second phase is a polymer liquid crystalline phase which includes polymer liquid crystals of the natural polysaccharide, the chemically modified natural polysaccharide, or the combination.

Abstract: A hair dye composition comprising the following components (A), (B) and (C) and having pH (25° C.) of 7.5 or more and 12 or less: (A): one or more azo dyes selected from the group consisting of the following (A-1), (A-2) and (A-3): (B): a cationic compound (C): 0.1 mass % or more and 8 mass % or less of at least one alkali metal salt of an acid selected from the group consisting of hydrochloric acid, carbonic acid and sulfuric acid.

Abstract: Hair treatment agents and methods for treating hair are presented herein. An exemplary hair treatment agent includes, based on its weight, (a) from about 0.001 to about 10 wt. % of at least one succinimidyl ester, and (b) from about 0.001 to about 20 wt. % of at least one proteolipid of formula (II) R?—X—R?. In formula (II), R? represents a straight-chain or branched, saturated or unsaturated hydrocarbon functional group having 11 to 24 carbon atoms; R? represents a protein, a peptide or a protein hydrolysate; and X represents —C(O)O— or —N+(RIII2)—RIV— or —N(RIII)RIV— or —C(O)—N(RV)RVI, where RIII represents —(CH2)x—CH3, where x=0-22, and RIV represents —CH2—CH(OH)—CH2— or —(CH2)X—, where x=0-22; and RV and RVI represent, independently of one another, —H or —(CH2)X—CH3, where x=0-22; wherein R? represents keratin or a keratin hydrolyzate when X represents —C(O)O—.

Abstract: A method of combating colour loss from a dyed material, the method comprising contacting the material with a composition comprising a compound of formula (I): (I) wherein R is an optionally substituted hydrocarbyl group having at least 5 carbon atoms, and R is hydrogen or a solubilising group.

Abstract: A method of treating a material, the method comprising the steps of: (1) contacting the material with a composition comprising an electrophilic species selected from aldehydes, succinimidyl esters, and mixtures thereof; (2) contacting the material with a composition comprising a chelating agent and/or a salt of an amine and/or a carboxylic acid.

Abstract: A method of combatting colour loss from a dyed material, the method comprising the steps of: (1) contacting the material with a composition comprising an electrophilic species selected from aldehydes, succinimidyl esters, and mixtures thereof; (2) contacting the material with a composition comprising a chelating agent and/or a salt of an amine and/or a carboxylic acid.

Abstract: The present invention relates to the use of at least one compatible solute and/or its physiologically acceptable salt for countering age-related skin color change or for the suppression and/or reduction of protein carbonylation and/or for the suppression and/or reduction of the accumulation of carbonylated proteins in the stratum corneum. The invention is further directed to formulations comprising at least one compatible solute and/or its physiologically acceptable salt and at least one further skin pore lightening active, as well as a process for preparing such formulation.

Abstract: The present invention relates to a composition comprising: (a) one more compound(s) of thiolactone type, and (b) one or more silicones.

Abstract: A powder composition for forming a cosmetic nail coating comprises an acrylic polymer or copolymer, and about 0.01 wt % to about 1.0 wt % of tertiary phosphine. The tertiary phosphine comprises three aryl groups, alkyl groups, or combination thereof. An example of the tertiary phosphine is a triaryl phosphine that may be substituted with 1 to 3 alkyl groups. A method of forming a cosmetic nail coating comprises the steps of (i) applying to a nail a cyanoacrylate adhesive; and (ii) contacting the nail with the powder composition. No application of an activator is necessary. The advantages of such a method include that fewer steps are needed in order to obtain a nail coating, the increased speed that the system cures, and a safer toxicological profile of the ingredients.

Abstract: A moisturizing base material that contains a lipid peptide compound including at least one of compounds of Formula (1) below and simulated compounds thereof or pharmaceutically usable salts thereof, a surfactant, a specific polyhydric alcohol, a fatty acid, and water. wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; and R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.

Abstract: A manufacturing method of an ascorbic acid dispersion material includes a heating step of adding an ascorbic acid into a solvent including one or more selected from the group consisting of glycerin, diglycerin, polyglycerin represented by a following formula, and propylene glycol, and heating the ascorbic acid to a predetermined temperature to dissolve the ascorbic acid; a cooling step of cooling a solution with the ascorbic acid dissolved therein at a cooling rate of 5 to 20° C./min until a temperature of the solution reaches 35 to 50° C. to remove heat from the solution; and a growth step of storing the solution after completion of the cooling step at 27 to 38° C. for a predetermined period to promote crystal growth so that the ascorbic acid crystal has a flat plate shape, a thickness of 0.05 to 3 ?m, and an average particle diameter of 50 to 100 ?m.

Abstract: A method of preparing a hydrogel product including crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include residual amine groups; and ii) acylating residual amine groups of the crosslinked glycosaminoglycans provided in i) to form acylated crosslinked glycosaminoglycans.

Abstract: A personal cleansing composition includes a surfactant system, wherein the surfactant system includes from 0.1% to 5% of a fatty acyl isethionate surfactant by weight of the composition; from 0.5% to 40% of a co-surfactant by weight of the composition; from 0.05% to 5% of a natural polysaccharide or a chemically modified natural polysaccharide by weight of the composition; wherein the personal cleansing composition includes a first and second phase, wherein the first phase is an isotropic and micellar surfactant phase; wherein the second phase is a polymer liquid crystalline phase; wherein the composition is free of alkyl sulfate and alkyl ether sulfate type of surfactants; wherein the composition exhibits a yield stress value ?y from 0.005 Pa to 3 Pa; and wherein the composition exhibits a flow viscosity from 3 Pa·s to 100 Pa·s at 25° C. at a shear rate of 1.5 s?1.

Abstract: Compositions, systems, kits and methods for forming a nail coating using a solid activator such as a powdered solid amine or solid component having an amine moiety. The powdered compositions may include a polymeric powder and a solid amine or solid component having an amine moiety. Systems and kits including the powdered composition and a liquid composition comprising a cyanoacrylate monomer are also provided. A method for forming a cosmetic nail coating using a solid activator is also provided. The method may include a) applying a liquid composition to a nail to form a wet nail, the liquid composition comprising a cyanoacrylate monomer, and b) applying to the wet nail a powdered composition, the powdered composition comprising a polymeric powder and a solid amine activator or solid component having an amine moiety.

Abstract: Provided is a method for forming a good fibrous coating on a target surface even in a high-humidity environment when electrostatically spraying is performed directly on the target surface such as skin. A composition for forming a coating of fibers on a target object by electrostatic spraying, comprising the following components (a), (b), (c) and (d): (a) 1 mass % or more and 45 mass % or less of a polymer having a film-forming ability; (b) 45 mass % to 95 mass % of one or more volatile substances selected from the group consisting of an alcohol and a ketone; (c) a conductivity controlling agent to control the conductivity of the composition to 8 ?S/cm or more and 300 ?S/cm or less; and (d) 0.2 mass % or more and 25 mass % or less of water.

Abstract: An anhydrous personal care composition, comprising: (a) 45 to 60 weight % of at least one ester, selected from (i) triglycerides, (ii) diglycerides, (iii) monoglycerides, (iv) monoesters of diols, and (v) diesters of diols; (b) a first wax having a melting point of from 35° C. to 72° C. present in an amount of 5 to 25 weight %; (c) a second wax having a melting point of 73 to 90° C. present in an amount of 0.5 to 15 weight %; and (d) at least one plant oil having a saponification value of from 150 to 275 mg KOH/g present in an amount of 5 to 35 weight.

Abstract: A natural-based mascara composition containing psyllium fibers mixed with other vegetable fibers, free of synthetic polymers and synthetic fibers, with optimal volumizing, elongation and adhesiveness to eyelashes characteristics is disclosed.

Abstract: The present invention relates to a skin external composition containing an extract of green tea produced by an extreme light-shielding cultivation method, which is distinguished from a conventional light-shielding cultivation method of green tea. More specifically, the present invention relates to a skin external composition, which contains an extract of green tea cultivated by extreme light-shielding, in which the amino acid content is remarkably increased by cultivating the green tea by a light-shielding cultivation under a light-shielding rate of 99% or more, thereby obtaining more excellent skin moisturizing, skin protecting, and anti-aging effects.

Abstract: Provided are botanical or bacterial extracts and methods of treating skin and other tissues by applying certain botanical or bacterial extracts, such as from Acronychia acidula, Licaria vernicosa, Calendula officinalis, Trigonella foenum-graecum or Actimomyces bacteria, to the skin or other tissue.

Abstract: Provided herein are methods for treating chronic pain by administering low doses of buprenorphine twice daily (or once daily) via a transmucosal drug delivery device. The methods and devices efficiently treat chronic pain without significant side effects.

Abstract: A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of a drug to the back of the neck of a human patient at the hairline in close proximity to and under or on the area of skin above the brain stem to provide regional neuro-affective therapy is disclosed.

Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.

Abstract: A non-invasive ocular drug delivery device can include a housing adapted to couple to an eye of a subject. An active agent matrix can be coupled to the housing. The active agent matrix can include an electrospun material having a combination of a density, a thickness, and an ocular surface area configured to hold and retain an active agent prior to application of the device to the eye, and deliver an effective dose of an active agent within 30 minutes of application of the device to the eye.

Abstract: The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having a coating made at least in part using printing technologies to provide drug storage and drug release structures. The coating preferably includes at least one drug reservoir layer and a least one barrier layer, and can include structures, such as but not limited to capillary structures that alone or in combination modulate the release of the drug from the coating. One aspect of the present invention is a medical device that incorporates a drug in at least one coating. A second aspect of the present invention is a method of making a medical device that incorporates a drug in at least one coating. A third aspect of the present invention is a method of using a medical device of the present invention to treat, prevent from having, prevent from developing, control, reduce the severity, or reduce the progression of a disease, disorder or condition of a subject.

Abstract: The present invention relates to a starch-free soft chew formulation for oral delivery of at least one active ingredient to an animal, and a starch-free soft chew containing the formulation and at least one active ingredient. The starch-free soft chew includes one or more active ingredients and excipients, such as a bulking agent, a flavoring agent, a humectant, a preservative, an antioxidant, and a lubricant, but no added water. In addition, the invention relates to a composition of starch-free, non-water excipients for use in the final dosage form of a soft chew for oral administration of at least one active ingredient to an animal. Also provided are processes for making the starch-free soft chew formulation and the starch-free soft chew.