Abstract: The present invention relates generally to the field of molecular biology. More particularly, it concerns methods and compositions for detecting, evaluating, and/or mapping 5-hydroxymethyl-modified cytosine bases within a nucleic acid molecule.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing a breast cancer. In particular, the present disclosure relates to combining simplified clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: cfRNA is used to identify and quantitate expression levels of disease related genes and further allows for non-invasive monitoring of changes in such genes. Moreover, quantitative analysis of disease related genes will enable prediction of treatment response where the treatment is dependent on the presence of the disease related gene.

Abstract: Methods and kits are provided for screening a patient for bladder cancer. Embodiments include those involving centromeric probes to chromosomes 3, 7, and 10 and a locus-specific probe to 5p15.

Abstract: Compositions and methods for detecting influenza are provided.

Abstract: The present invention relates to a mutant fungal strain of Penicillium funiculosum ‘MRJ-16’ characterized by the ability to produce high titer of enzyme mixture comprising FPase, CMCase, Cellobiase, ?-glucosidase, endoglucanase, ?-L arabinofuranosidase, ?-xylosidase, xylanase, pectinase, cellobiohydrase and oxidases and produce enzymes in the presence of a catabolite repressor molecule like glucose and/or xylose. The titer of enzyme mixture produced using mutant fungal strain MRJ-16 is at least two fold higher than naive Penicillium funiculosum strain NCIM 1228, when used in a fermentation process. The mutant strain ‘MRJ-16’ with high hydrolytic activity and catabolite derepressed character is having application in the method of degrading or saccharifying biomass to produce valuable products for example-bioethanol.

Abstract: Disclosed is super-high-strength tool steel having high impact toughness, including 0.7 to 0.9 wt % of C, 0.4 to 0.6 wt % of Si, 0.4 to 0.6 wt % of Mn, 7.0 to 9.0 wt % of Cr, 1.5 to 2.5 wt % of Mo, 1.0 wt % or less (excluding 0 wt %) of V, and at least one of 0.1 wt % or less (excluding 0 wt %) of Ti and 0.1 wt % or less (excluding 0 wt %) of Ce, with the remainder of Fe and inevitable impurities. The super-high-strength tool steel having high impact toughness includes at least one of Ti and Ce, thus reducing primary carbide content in an as-cast state and exhibiting improved impact toughness at a high hardness level after solution treatment and tempering. In addition, a method of manufacturing super-high-strength tool steel having improved impact toughness at a high hardness level is provided.

Abstract: A railway wheel in which formation of pro-eutectoid cementite is suppressed is stably produced. After heating an intermediate product containing, in mass %, C: 0.80 to 1.15% to a temperature not less than Acm transformation point, the intermediate product is cooled such that the cooling rate (° C./sec) in a range from 800 to 500° C. satisfies the following conditions: Surface other than the tread and the flange surface: not more than Fn1 defined by Formula (1), Cooling rate in a region in which cooling rate is slowest: not less than Fn2 defined by Formula (1), and Tread and flange surface: not less than Fn2: Fn1=?5.0+exp(5.651?1.427×C?1.280×Si?0.7723×Mn?1.815×Cr?1.519×Al?7.798×V)??(1) Fn2=0.515+exp(?24.816+24.121×C+1.210×Si+0.529×Mn+2.458×Cr?15.116×Al?5.

Abstract: A steel sheet for a two-piece can, the steel sheet includes: by mass %, C: 0.010% or more and less than 0.030%; Si: 0.04% or less; Mn: 0.10% or more and less than 0.40%; P: 0.02% or less; S: 0.020% or less; Al: more than 0.030% and 0.100% or less; N: 0.0005% or more and less than 0.0030; B: 0.0005% to 0.0030%; and balance Fe and inevitable impurities, wherein an amount of N that is present as BN and a whole amount of N satisfy the following expression (1): [N as BN]/[N]>0.5 ??(1), where N as BN represents the amount of N that is present as BN, and N represents the whole amount of N, a yield point is more than 280 MPa and less than 420 MPa, yield elongation is 3% or less, and ?r is ?0.30 to 0.20.

Abstract: A process of producing a fine-grained austenitic stainless steel, said process comprising a step of subjecting a fine-grained austenitic stainless steel comprising: C: 0.15 wt % or less, Si: 1.00 wt % or less, Mn: 2.0 wt % or less, Ni: 6.0 to 14.0 wt %, Cr: 16.0 to 22.0 wt %, and Mo: 3.0 wt % or less, with the balance being Fe and inevitable impurities, and having an average grain size of 10 ?m or lower, to an annealing treatment at a temperature from 600° C. to 700° C. for 48 hours or longer.

Abstract: The invention discloses an on-line intelligent control method for the cooling characteristics of a quenching liquid in heat treatment production, which comprises the steps of: step 1: subjecting a workpiece to thermal insulation; step 2: measuring the cooling characteristics and the heat transfer coefficient of a quenching liquid followed by correction; step 3: starting cooling; step 4: then changing the internal circulation rate; and step 5: removing the workpiece. This scheme can effectively avoid the problem that the cooling of a workpiece in industrial production deviates from the ideal cooling characteristics of a quenching liquid obtained in a laboratory.

Abstract: The invention concerns a method of operating a sinter plant, where a sinter mix is fired in a sintering machine, the method including crushing fired sinter to below an upper particle size limit; screening the crushed sinter to remove fines and separate at least two sinter size fractions, typically smaller, intermediate and upper size fractions; storing each of the at least two sinter size fractions in a respective, separate storage bin, where the screened sinter fractions are not mixed again at the sinter plant but are forwarded to the blast furnace plant, where they are stored in respective, separate storage bins, and the screened sinter fractions can be intermediately stored in separate bins at the sinter plant, before being forwarded to the blast furnace.

Abstract: The present disclosure relates to novel nickel-base alloy compositions including 7.25-7.75 wt % Cr, 0.6-1.0 wt % Mo, 8.5-9.1 wt % W, 6.0-6.4 wt % Al, 0.6-1.0 wt % Ti, 0.06-0.10 wt % C, 0.01-0.02 wt % B, 0.4-0.6 wt % Hf, and at least one of: 8.6-9.6 wt % Co and 4.0-4.8 wt % Ta; or 8.6-9.4 wt % Co, 3.8-4.4 wt % Ta, and 0.4-0.6 wt % Re, with the balance being nickel and trace impurities. Gas turbine blades or guide vanes are also provided, where the blades or vanes are formed using an alloy having such compositions.

Abstract: A high temperature alloy is disclosed. The high temperature alloy may have on a weight basis: about 9.0-10.0 weight % of Co, about 0.25 weight % maximum of Fe, about 8.0-9.0 weight % of Cr, about 4.75-5.50 weight % of Al, about 1.0-1.5 weight % of Ti, about 0-2.0 weight % of Mo, about 6.0-9.0 weight %, of W, about 0.12-0.18 weight % of C, about 0.01-0.03 weight % of Zr, about 0.005-0.015 weight % of B, about 0.5-1.5 weight % of Ta, a balance of Ni, and incidental impurities.

Abstract: A low thermal expansion alloy having a high rigidity and a low thermal expansion coefficient comprising, by mass %, C: 0.040% or less, Si: 0.25% or less, Mn: 0.15 to 0.50%, Cr: 8.50 to 10.0%, Ni: 0 to 5.00%, and Co: 43.0 to 56.0%, S: 0 to 0.050%, and Se: 0 to 0.050% and having a balance of Fe and unavoidable impurities, the contents of Ni, Co, and Mn represented by [Ni], [Co], and [Mn] satisfying 55.7?2.2[Ni]+[Co]+1.7[Mn]?56.7 and the structure being an austenite single phase.

Abstract: A Mg—Gd—Y—Zn—Zr alloy with high strength and toughness, corrosion resistance and anti-flammability and a process for preparation thereof are disclosed. The components and the mass percentages thereof in the Mg—Gd—Y—Zn—Zr alloy are: 3.0%?Gd?9.0%, 1.0%?Y?6.0%, 0.5%?Zn?3.0%, 0.2%?Zr?1.5%, the balance being Mg and inevitable impurities. The process for preparation thereof comprises: adding pure Mg into a smelting furnace for heating, then introducing mixed gases of CO2 and SF6 into the furnace for protection; adding other raw materials in sequence when the pure Mg is completely melted; preparing an ingot; conducting a homogenization treatment on the ingot prior to extrusion; conducting an aging treatment on the extruded alloy.

Abstract: A steel sheet of the present invention has a steel structure obtained by performing a soaking at a dual phase region temperature of Ac1 temperature or higher and lower than Ac3 temperature for a soaking time of 15 seconds or longer and 35 seconds or shorter, next, performing a primary cooling to a temperature range of 250° C. or higher and 380° C. or lower within 3 seconds at a cooling rate of 0.5 ° C./s or more and 30° C./s or less, and performing a retention in a temperature range of 260° C. or higher and 370° C. or lower for 180 seconds or longer and 540 seconds or shorter, in which a yield ratio is 65% or less and tensile strength is 590 MPa or more after the primary cooling.

Abstract: Described herein are coiled tubes with improved and varying properties along the length that are produced by using a continuous and dynamic heat treatment process (CDHT). Coiled tubes can be uncoiled from a spool, subjected to a CDHT process, and coiled onto a spool. A CDHT process can produce a “composite” tube such that properties of the tube along the length of the tube are selectively varied. For example, the properties of the tube can be selectively tailored along the length of the tube for particular application for which the tube will be used.

Abstract: This invention concerns a method of improving the wear resistance of a cemented carbide. The method includes using fracture toughness as a selection criterion and selecting a cemented carbide which has a fracture toughness between about 6 and about 15 MPa·m1/2. The method further includes applying a sacrificial coating to the cemented carbide and increasing the fracture toughness of the cemented carbide by creating a toughened surface layer using laser shock peening, thereby increasing its fracture resistance to fatigue and stress corrosion cracking. The invention also concerns a cutting tool or a cutting tool insert made from a cemented carbide and treated using the method according to the invention.

Abstract: Provided is an alloy material including a metal oxide thin layer that can be formed using a simple method at low cost and can further suppress volatilization of Cr, which causes deterioration of a fuel cell, compared with a case where conventional expensive materials are used. Disclosed is a manufacturing method for an alloy material including a coating treatment step for coating a substrate made of a Fe—Cr based alloy with Co, and an oxidation treatment step for performing oxidation treatment on the substrate in a moisture-containing atmosphere after the coating treatment step.

Abstract: A mask assembly, and an apparatus and method for manufacturing a display apparatus by using the mask assembly are provided. A mask assembly includes: a mask frame; a mask sheet on the mask frame and including a plurality of openings; at least two first shielding sheets on the mask frame and shielding some of the plurality of openings of the mask sheet; and at least two second shielding sheets on the mask frame and shielding some of the plurality of openings of the mask sheet, the at least two first shielding sheets and the at least two second shielding sheets define a deposition area including some of the plurality of openings of the mask sheet by shielding some of the plurality of openings of the mask sheet, and the deposition area is divided into a first deposition area and a second deposition area.

Abstract: A method of manufacturing a mask frame assembly includes: welding fixing ends of a long-side support bar on a frame; and fixing a mask having a pattern area to be divided by the long-side support bar, on the frame, wherein the welding of the fixing ends of the long-side support bar on the frame includes forming welds asymmetrically with respect to a longitudinal central axis of the fixing ends.

Abstract: A coated cutting tool includes a substrate of cemented carbide, cermet, cBN, ceramics or HSS and a coating of a nitride layer, which is a High Power Impulse Magnetron Sputtering (HIPIMS) deposited layer of a nitride of one or more of Ti, Zr, Hf, V, Ta, Nb, Cr, Si and Al, and a HIPIMS-deposited oxide layer being an (AlaMe1?a)2O3 layer, 0.05?a?1, wherein Me is one or more of Ti, Mg, Ag, Zr, Si, V, Fe, Hf, B and Cr. The oxide layer is situated above the nitride layer. Also, a method is disclosed for producing a coated cutting tool having the nitride layer and oxide layer, the nitride layer and the oxide layer being deposited by a HIPIMS process.

Abstract: An alkali-metal dispenser to dispense highly pure rubidium in a high-vacuum environment while not negatively impacting the high-vacuum pressure level. The alkali-metal dispenser is operable in various vapor-deposition applications or to provide a highly pure elemental-alkali metal in cold-atom magneto-optical traps.

Abstract: The present disclosure provides a crucible. The crucible includes a crucible body having an opening formed at the top thereof. The crucible further includes a sealing cover and an elastic element. The sealing cover is configured to seal the crucible in a first position and open the crucible in a second position. In the first position, the sealing cover forms a detachable sealed connection with the crucible body. The elastic element is arranged between the sealing cover and the crucible body, where the elastic element is in a compressed state when the crucible is sealed by the sealing cover in the first position. Correspondingly, the present disclosure also provides an evaporation preparation device, evaporation equipment and an evaporation method. The present disclosure can reduce the deterioration of the material to be evaporated and the direct contact between human body and the material.

Abstract: The present disclosure provides a picking assembly, a crucible picking device, and a method for a picking crucible. The picking assembly may include a transmission shaft; at least two rigid balls; and a support member carrying rigid balls of the at least two rigid balls. Two of the at least two rigid balls may be arranged on two opposite sides of the transmission shaft. Centers of the two of the at least two rigid balls and a center of a cross-section of the transmission shaft may be located on a same line. The transmission shaft may be movable back and forth in an axis direction of the transmission shaft.

Abstract: Method for forming a metallic component surface to achieve lower electrical contact resistance. The method comprises modifying a surface chemical composition and creating a micro-textured surface structure of the metallic component that includes small peaks and/or pits. The small peaks and pits have a round or irregular cross-sectional shape with a diameter between 10 nm and 10 microns, a height/depth between 10 nm and 10 microns, and a distribution density between 0.4 million/cm2 and 5 billion cm2.

Abstract: In various embodiments, eroded sputtering targets are partially refurbished by spray-depositing particles of target material to at least partially fill certain regions (e.g., regions of deepest erosion) without spray-deposition within other eroded regions (e.g., regions of less erosion). The partially refurbished sputtering targets may be sputtered after the partial refurbishment without substantive changes in sputtering properties (e.g., sputtering rate) and/or properties of the sputtered films.

Abstract: Disclosed is a method of producing a multicomponent nanopattern having a regular array and allowing a variety of combinations of compositions by depositing a film including a multicomponent material on a substrate having a prepattern formed thereon and then conducting ion-etching thereon twice. The method can be utilized in a variety of applications requiring considerably regularly arranged multicomponent nanostructures such as transistors, organic optoelectronic devices, catalysts and gas sensors.

Abstract: A semiconductor device is manufactured by modifying an electromagnetic field within a deposition chamber. In embodiments in which the deposition process is a sputtering process, the electromagnetic field may be modified by adjusting a distance between a first coil and a mounting platform. In other embodiments, the electromagnetic field may be adjusted by applying or removing power from additional coils that are also present.

Abstract: An apparatus for depositing a metal film on a surface of a three-dimensional object, includes a mounting drum rotatably disposed inside a chamber and having a circumferential surface onto which a plurality of three-dimensional objects is settled and mounted making each surface thereof to be subjected to deposition be exposed to an outside; and at least one source target depositing a metal film onto the surface of the three-dimensional object mounted to the mounting drum by sputtering.

Abstract: The subject of the invention is the use, as catalyst support sublayer in a process for growing carbon nanotubes by chemical vapour deposition (CVD), of a multilayer stack formed of alternating layers of silica and of alumina, each of the layers having a thickness of less than or equal to 10 nm and consisting of one or more superposed atomic monolayer(s). It also relates to a multilayer structure comprising a substrate which has, on at least one of its faces, such a multilayer stack, and also to the use thereof for the growth of a mat of carbon nanotubes, which are in particular spinnable, by chemical vapour deposition, preferably hot-filament chemical vapour deposition.

Abstract: A reactor system and related methods are provided which may include a heating element in a wafer tray. The heating element may be used to heat the wafer tray and a substrate or wafer seated on the wafer tray within a reaction chamber assembly, and may be used to cause sublimation of a native oxide of the wafer.

Abstract: Embodiments related to measuring process pressure in low-pressure semiconductor processing environments are provided. In one example, a semiconductor processing module for processing a substrate with a process gas in a vacuum chamber is provided. The example module includes a reactor positioned within the vacuum chamber for processing the substrate with the process gas and a pressure-sensitive structure operative to transmit a pressure transmission fluid pressure to a location exterior to the vacuum chamber. In this example, the pressure transmission fluid pressure varies in response to the process gas pressure within the vacuum chamber.

Abstract: A method is provided, including the following operations: simultaneously applying an organosilyl chloride inhibitor and a Lewis base to a surface of a substrate, the organosilyl chloride inhibitor being configured to adsorb onto dielectric regions of the surface of the substrate; performing a plurality of cycles of an ALD process to deposit a metal oxide onto the surface of the substrate; wherein the applying of the organosilyl chloride inhibitor and the Lewis base prevents the ALD process from depositing the metal oxide onto the dielectric regions of the surface of the substrate.

Abstract: Multi-station process chamber lids comprising a plurality of station openings are described. A station separation purge channel is around the station openings. A plurality of angular purge channels separate station openings from adjacent station openings. A lid support beam can compensate for deflection of the chamber lid body.

Abstract: There is provided an injector that extends in a longitudinal direction, including: a gas introduction part having a circular or a regular polygonal shape in a cross section perpendicular to the longitudinal direction and having no discharge holes; and a gas supply part having a protruded portion in one direction in the cross section perpendicular to the longitudinal direction, and having a plurality of discharge holes formed in a leading end of the protruded portion along the longitudinal direction, wherein a first end of the gas supply part in the longitudinal direction is connected to the gas introduction portion.

Abstract: A substrate retaining apparatus, a load lock assembly comprising the substrate retaining apparatus, and a system including the substrate retaining apparatus are disclosed. The substrate retaining apparatus can include at least one sidewall and one or more heat shields. One or more of the at least one sidewall can include a cooling fluid conduit to facilitate cooling of substrates retained by the substrate retaining apparatus. Additionally or alternatively, one or more of the at least one sidewall can include a gas conduit to provide gas to a surface of a retained substrate.

Abstract: A substrate processing apparatus includes a rotary table comprising a base plate having a front surface where at least one suction hole is provided and an attraction plate having a front surface contacted with a non-processing surface of a substrate to attract the substrate, a rear surface contacted with the front surface of the base plate, and at least one through hole through which the front surface and the rear surface are connected; a rotation driving device configured to rotate the rotary table around a rotation axis; and a suction device configured to act a suction force on the suction hole, to contact the base plate with the attraction plate by acting the suction force between the base plate and the attraction plate, and to firmly contact the attraction plate with the substrate by acting the suction force between the attraction plate and the substrate through the through hole.

Abstract: An oxygen-free or oxygen-poor solution for the electroless deposition of a platinum group metal is described. The solution includes a ruthenium (II) amine complex having a first oxidation potential, and a platinum group metal compound having a reduction potential larger than the opposite of the oxidation potential of the ruthenium (II) amine complex.

Abstract: A steel piston for an internal combustion engine includes an amorphous phosphate layer in at least one region thereof. On account of this layer the adhesion of an antifriction coating is improved.

Abstract: An etch chemistry solution for treating metallic surfaces in which the etch chemistry solution includes an oxidizing agent and gluconic acid. The etch chemistry solution may also include an oxidizing agent and a short-chained polyethylene polymer glycol or a short-chained polyethylene copolymer glycol. The metallic surfaces are usually used in circuits such as flexible circuits.

Abstract: Methods and apparatus are disclosed. The apparatus includes a substantially cylindrical mount body (350) comprising a first open mouth at a first end of the cylindrical body (350) and a further open mouth at a remaining end of the cylindrical body, a substantially cylindrical inner surface, and an outer surface that includes a plurality of spaced apart substantially parallel recessed regions that extends circumferentially around the body, wherein the cylindrical body (350) is tapered at each end and at least one securing element is located between the recessed regions.

Abstract: A water electrolyzer comprises a membrane, a cathode and an anode. The membrane comprises a first membrane layer comprising a first ion-conductive polymer, a second membrane layer comprising a second ion-conductive polymer, and a platinized nanostructured layer disposed between the first layer and the second layer. The platinized nanostructured layer comprises close-packed whiskers having at least one of platinum or platinum oxide disposed thereon. The cathode is disposed on the membrane and comprises a first catalyst consisting essentially of both metallic Pt and Pt oxide. The anode is disposed on the opposite surface of the membrane and comprises a second catalyst comprising at least 95 percent by weight of collectively metallic Ir and Ir oxide, calculated as elemental Ir, based on the total weight of the second catalyst, wherein at least one of metallic Ir or Ir oxide is present. Membranes and methods of making them are also disclosed.

Abstract: A water electrolyzer comprising a membrane comprising at least one of metallic Pt or Pt oxide, a cathode, and an anode. The cathode comprises a first catalyst consisting essentially of both metallic Pt and Pt oxide. The anode comprising a second catalyst comprising at least 95 percent by weight of collectively metallic Ir and Ir oxide present, calculated as elemental Ir, based on the total weight of the second catalyst.

Abstract: Electrocatalysts of formula Al?x,BxO3??, wherein A=a metal with an acid-stable oxide and B=a platinum-group-metal (PGM), are provided, as are methods of making the electrocatalysts via rapid plasma oxidation, methods of using the electrocatalysts to catalyze e.g. oxygen evolution reactions (OERs), and devices comprising the electrocatalysts.

Abstract: The present invention relates to an electrode for electrolysis, a laminate, a wound body, an electrolyzer, a method for producing an electrolyzer, a method for renewing an electrode, a method for renewing a laminate, and a method for producing a wound body. An electrode for electrolysis according to one aspect of the present invention has a mass per unit area of 48 mg/cm2 or less and a force applied per unit mass·unit area of 0.08 N/mg·cm2 or more.

Abstract: A composite membrane that is suitable for use in a molten alkaline water electrolyzer. In one embodiment, the composite membrane includes a porous support, the porous support being in the form of a matrix of metal oxide particles randomly arranged to form a plurality of tortuous pores. The composite membrane also includes molten electrolyte filling the pores of the porous support, the molten electrolyte having hydroxide ion conductivity. The molten electrolyte may be a single species of an alkali hydroxide or of an alkaline earth hydroxide. Alternatively, the molten electrolyte may be a eutectic or non-eutectic mixture of two or more species of alkali hydroxides or alkaline earth hydroxides. The composite membrane may further include one or more additives, such as a coarsening inhibitor, a crack attenuator, and a reinforcing material. The composite material may be used to make a molten alkaline membrane water electrolyzer with high electrical efficiencies.

Abstract: A method for manufacturing a titanium-plated member includes: preparing a substrate having an electrically conductive surface; immersing the substrate in a molten-salt titanium plating solution composition containing ions of at least one Group I metal selected from the group of Li+ and Na+, F?, and Tin+; forming a titanium plating film on the surface of the substrate by applying electric current to cause the substrate immersed in the molten-salt titanium plating solution composition to serve as a cathode and cause the surface of the substrate to be coated with titanium; cleaning the titanium plating film by bringing the titanium plating film into contact with a cleaning molten salt, the cleaning molten salt containing at least one compound selected from the group consisting of alkaline metal chloride, alkaline earth metal chloride, and potassium fluoride; and cleaning the titanium plating film with water.

Abstract: Provided in one example is a sensor having at least one fissure, the fissure being at least partially filled by at least one polymer formation extending vertically within a passivation layer. The polymer formation protects the underlying metal containing layer from corrosive solutions. Provided in another example is a method of forming the polymer formation in a fissure of a sensor.