Abstract: A method in gait rehabilitation for detecting a foot being lifted comprises: receiving (102) a plurality of signals from respective pressure sensors (12), mounted beneath a foot of a person, each signal providing a time sequence of values representing asserted pressure; processing the received signals, wherein said processing comprises, for each signal, assigning states to the respective pressure sensor (12) for determining when the foot is being lifted for walking, and wherein said assigning of states comprises: identifying that the sequence of values are maintained above an upper threshold (32) for a duration exceeding a time threshold (36); and upon such identifying assigning a prepared state to the sensor (12); and, when the sensor (12) is in the prepared state, identifying (108) a value below a lower threshold (34) indicating that the foot is potentially lifted; and upon such identifying assigning an unprepared state to the sensor (12); and wherein said processing further comprises, when assigning an unp

Abstract: A tissue thickness measuring device includes an elongate member defining a first lumen therethrough, an inner shaft slidably received in the first lumen, a tool assembly, and an actuation rod dimensioned to be received through the inner shaft. In particular, the tool assembly includes a neck portion and first and second jaw members. The neck portion is operatively supported on the inner shaft such that the tool assembly is transitionable between a retracted state and an extended state. The first jaw member is fixedly secured with the neck portion. The second jaw member is movable relative to the first jaw member between an approximated position and a spaced apart position. The actuation rod is configured to be selectively coupled with the second jaw member. Rotation of the actuation rod transitions the second jaw member between the approximated and spaced apart positions.

Abstract: A device is disclosed to assist in the determination of the presence and type of dyskinesia in a patient. The device includes a sensor, removably attachable to a patient's body, such as on a limb or torso, the sensor being capable of detecting 3-D motion. Data generated by the sensor is transferred to and retained in a data retention means. A processing means is included to process the generated data, along with a look-up table of processed data for already known dyskinesia conditions for comparison, the processing means employs an evolutionary algorithm in the classification of the data. Output means display the diagnosed condition to a user.

Abstract: Embodiments of the present disclosure relate generally to devices and systems for administering pharmaceutical, monitored and/or biological agents via nebulization to a subject. In certain embodiments, the present disclosure provides devices, methods and systems for bio-metric and diagnostic data acquisition and patient monitoring before, during, and after the nebulization and administration of pharmaceutical, monitored and/or biological agents to a subject. In yet other embodiments, devices, systems and methods disclosed herein provide for delivery of agents where patients have an increased level of control over the delivery of their medication and by providing healthcare providers with meaningful and accurate biomctric and diagnostic data during treatment.

Abstract: A system for sensing and assessing movement, the system comprising a sensing arrangement for sensing movement in a space, the sensing arrangement comprising a plurality of sensors, at least some of which are adapted to sense movement on a surface and at least some of which are adapted to sense movement in a space; a receiving unit adapted to receive data from the sensing arrangement; a system for interpreting that data to provide an assessment of movement; an interface adapted to display that assessment of movement and provide a visual indicator of relative impact.

Abstract: Aspects describe capturing the dynamic movement of one or more leaders and generating stimulus signals in real time for one or more followers to perform substantially the same movement. A model of each follower is optionally employed to transform the observed movement of a leader to a series of movement cues that will overcome any follower physical and cognitive limitations while maximizing the movement compliance and benefit from the directed movement. Also provided is the capability of establishing a library of therapeutic, fitness, rehabilitation or dance movement scripts that may be replayed at the follower's convenience without a leader present. Additionally, one aspect provides for continually monitoring follower movement to detect unstable movement, an increased likelihood of a fall and gait anomalies and initiating a stimulus pattern to reduce the chance of a fall or injury.

Abstract: The present invention concerns a method for the detection of distortion products of otoacoustic emissions (DPOAE), comprising the steps: (a) output of at least one first pair of primary tones each consisting of a first primary tone with frequency f1,1 and sound pressure level L1,1 and a second primary tone with frequency f2,1 and sound pressure level L2,1 with f2,1>f1,1, and (b) detecting evoked distortion products of otoacoustic emissions (DPOAE), characterized in that the first primary tone {f1,1, L1,1} is output with a time delay tlag after the second primary tone {f2,1, L2,1}.

Abstract: A sensor comprises a microfabricated chip having a surface with one or more cavities formed thereon, the cavities including sensing components, one or more lids, each covering said surface so as to close at least one of said cavities, the lids contacting rims that delimit said cavities on said surface. Electric circuit portions join, each, a respective one of the lids, to allow the lids to be partly dissolved, electrochemically, responsive to being exposed to an electrochemical solution. In addition, masking material portions cover peripheral regions of the lids at the level of the rims, so as to seal the lids and shield such peripheral regions from said electrochemical solution, in operation. Related apparatuses and sensing methods may be provided.

Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.

Abstract: A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more compounds containing boronate or boronic acid moieties that reduce degradation of the analyte indicator.

Abstract: A pH sensor for measuring pH levels within a measurement environment is described. The sensor comprises a reference electrode, a pH sensitive electrode, and a controller, for measuring the potential difference between the pH sensitive electrode and the reference electrode, the measured potential difference being indicative of a pH level at the pH sensitive electrode. The controller is operable to apply a voltage across first and second electrodes to control the pH level at the pH sensitive electrode, and to measure the potential difference between the pH sensitive electrode and the reference electrode following the application of the recalibration voltage. In this way, recalibration of the pH sensor is possible within the measurement environment.

Abstract: Described herein are devices for collecting and analyzing a fluid sample, the devices comprising a fluid-collecting porous material comprising at least one hydrophilic porous layer and one or more sensors adapted to provide a response to the presence of an analyte. The detectors are useful for collecting and analyzing a very small volume of sample and may include features that facilitate and direct flow of the sample through porous material.

Abstract: A blood sampling device (1) comprising a housing (10) and a lancet (50). The housing has a fixed abutment surface for holdingly engaging the lancet in a rearward primed position. The blood sampling device further comprises a trigger (22) moveable from a rest position to a fire position to release the lancet for forward movement, wherein the trigger deflects the lancet body in a direction generally transverse to the longitudinal axis of the housing such that the lancet body may move forwardly past the fixed abutment surface.

Abstract: A portable complex sensor device for measuring multiple items of biometric information, according to the present invention, comprises: a plurality of electrodes for receiving the biometric information; a plurality of biometric information measuring circuits for measuring the biometric information received from the plurality of electrodes; a plurality of current sensors which are always supplied with power so as to sense electric current when an object to be measured contacts the electrodes; a wireless communication means for transmitting and receiving data to and from a smart phone; and a microcontroller for controlling the power supply of a battery by being operated in a sleep mode or an active mode on the basis of whether the current sensors have sensed the electric current.

Abstract: Embodiments described herein relate to systems, devices, and methods for use in the implementation of a brain-computer interface that integrates real-time eye-movement tracking with brain activity tracking to present and update a user interface that is strategically designed for high speed and accuracy of human-machine interaction. Embodiments described herein also relate to the implementation of a hardware agnostic brain-computer interface with specific user interface adaptations to enable high-speed, intuitive, and accurate user manipulation of applications and/or machines.

Abstract: The invention is a lie detector for the heart.

Abstract: A computer system for generating a diagnostic tool by applying artificial intelligence to an instrument for diagnosis of a disorder, such as autism. For autism, the instrument can be a caregiver-directed set of questions designed for an autism classification tool or an observation of the subject in a video, video conference, or in person and associated set of questions about behavior that are designed for use in a separate autism classification tool. The computer system can have one or more processors and memory to store one or more computer programs having instructions for generating a highly statistically accurate set of diagnostic items selected from the instrument, which are tested against a first test using a technique using artificial intelligence and a second test against an independent source. Also, a computer implemented method and a non-transitory computer-readable storage medium are disclosed.

Abstract: A state display apparatus includes a display section that displays a state of a measurement target subject based on biometric data of the measurement target subject; and a control section that performs control such that a display mode at the time of displaying a state of the measurement target subject next time onwards is changed so as to be different from a display mode at the time of displaying a first state based on first biometric data of the measurement target subject, in a case where second biometric data acquired at the time of displaying the first state on the display section satisfies a predetermined condition, at the time of performing control such that the display section displays the first state.

Abstract: Systems and methods for predicting emotional state, behavioral state, or mood of a subject including a non-contacting physiologic sensing apparatus, as well as, possibly, an image capture sensor or a microphone, which may be incorporated into an article of furniture, for detecting parameters indicative of emotional state of a non-recumbent subject.

Abstract: A system and method for detecting abnormal motor vehicle operation and providing notification and alerts to third parties, comprising: an impediment proximity detection subsystem including sensors at least mounted at external surfaces of said vehicle, said impediments consisting of at least fixed and moving objects external to said vehicle; a vital sign detection subsystem installed in said vehicle, including driver monitoring sensors and providing a measure of at least driver pulse rate and hand location; a controller installed in said vehicle, for receiving and processing sensor produced signals; an alarm subsystem installed in said vehicle, producing at least one of a visual or vibrational signal; a cloud interface subsystem including at least a WiFi transceiver installed in said vehicle, and a Google Cloud IoT Service or equivalent, and a vehicle to vehicle communication subsystem installed in said vehicle, using the BroadR-Reach® standard for automotive Ethernet or its evolving equivalents.

Abstract: A non-transitory tangible computer-readable medium or media include one or more sequences of instructions which, when executed by one or more processors, causes steps to be performed, where the steps include receiving data obtained from baseline clinical evaluation and a urodynamic test for a patient, the diagnostic engine having been trained to associate a data obtained from a urodynamic test with one or more lower urinary tract dysfunction; extracting one or more features from the received data; identifying one or more urodynamic parameters of the patient's lower urinary tract dysfunction, based on the one or more extracted features; and generating an output that includes information of one or more lower urinary tract dysfunction associated with the one or more identified urodynamic parameters.

Abstract: A system comprising: a) a toilet comprising a toilet bowl for receiving excreta; b) a detection unit mounted to the toilet bowl and comprising: (i) one or more detectors selected from a group consisting of one or more laser triangulation sensors, an infrared sensing device and a Doppler velocimeter), (ii) a data processor, (iii) a data storage device, (iv) a wireless transmitter to transmit data from the detectors to a communications network and (v) a power source, wherein the one or more sensors are positioned measure characteristics of excreta deposited in the toilet bowl; and c) a computer configured to receive the data over the communications network and comprising memory including computer code to analyze the data and determine an amount of urine and/or feces deposited into the toilet bowl, and a processor to execute the code.

Abstract: A cognitive function determination method includes applying a load including a sensory stimulus (5a) or tasks with different degrees of difficulty a plurality of times (S1), measuring a change in brain activity of a subject (P) when the load is applied and acquiring measurement data (S2), and determining a degree of cognitive function of the subject (P) (S3).

Abstract: This brain activity feature amount extraction method includes acquiring a combination of a plurality of data items in order of higher effectiveness for discriminating whether a subject is a healthy person or a non-healthy person, among the plurality of data items, on the basis of the index value serving as the index indicating effectiveness or non-effectiveness for discriminating the group of healthy persons and the group of non-healthy persons from each other, and displaying the acquired combination of the plurality of data items in order of higher effectiveness.

Abstract: This disclosure relates generally to a Parkinson's disease detection system. Parkinson's disease is a neuro-degenerative disorder affecting motor and cognitive functions of subjects. Since symptom manifestation is limited in Parkinson's disease, identifying Parkinson's disease in the early stage is a challenging task. The present disclosure overcomes the limitations of the conventional methods for detecting Parkinson's disease by utilizing a graph theory approach. Here, each pressure sensor attached to an insole corresponding to a plurality of pressure points associated with a foot of the subject is considered as a node of a connectivity graph. The foot dynamics analysis is performed based on a metric known as mediolateral stability index and the mediolateral stability index is calculated by utilizing a betweenness centrality associated with each node of the connectivity graph. Further, the mediolateral stability index is compared with standard values to detect the intensity of the Parkinson's disease.

Abstract: A swallowing movement measuring device measures an examinee's swallowing movement. The device measures a movement of the examinee's larynx when the examinee swallows a food bolus. This device has a capacitive sensor to be brought into contact with a body skin of the examinee's laryngeal part, and a measuring unit that measures a change of the capacitive sensor in capacitance. This capacitive sensor includes a sensor body comprising sheet-like dielectric layer, a first electrode layer and a second electrode layer. The first and the second electrode layers are formed on a top surface and a bottom surface of the dielectric layer respectively, and are at least partially opposed to each other across the dielectric layer. The partially opposed portions of the electrode layers constitute a detection portion. The sensor body is reversibly deformable to change areas of the top and bottom surfaces of the dielectric layer.

Abstract: A walking training system and walking training machine capable of remarkably enhancing the effect of improving an independent walking function are proposed. When a subject having a lower limb functional disorder performs walking training, the degree of dependency on upper limbs can be evaluated by enabling the subject to recognize transitional reductions of a load on a holding part(s) by feeding back the transitional reductions of the load as a sense to feel them.

Abstract: In an information processing method, a computer acquires a sleep state of a person existing in space, acquires detection data output from a sensor that detects entry of an object into the space, performs a first determination to determine whether or not the sleep state changes to awakening within a predetermined time from a time point at which the object is estimated to enter the space based on the sleep state and the detection data, generates, in association with the sleep state before the time point, awakening information for determining possibility that the person is awakened by entry of the object in a case where the person is in the sleep state before the time point of entry based on a result of the first determination, and presents the awakening information associated with the sleep state via a presentation device.

Abstract: Embodiments of the present disclosure provide a device for determining a location of a blood vessel and a method thereof. The device includes a plurality of sensors, a processor, and an indicating device. The plurality of sensors may detect pressure values at a plurality of skin locations in contact with the plurality of sensors. The processor may determine the location of the blood vessel based on the pressure values. The pressure value at the skin location corresponding to the location of the blood vessel is greater than the pressure values at both sides of the skin location in a direction perpendicular to a direction of the blood vessel. The indicating device may indicate the location of the blood vessel.

Abstract: A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter configured to emit light of two different wavelengths. The system also includes at least one light sensor disposed opposite the at least one light emitter, the at least one light sensor configured to detect light at the two different wavelengths and to provide a signal having a pulsatile and a non-pulsatile component for each wavelength. The system further includes a controller coupled to the at least one light sensor and configured to determine and indicate if the vessel is a ureter within the region proximate to the working end of the surgical instrument based on a ratio and a symmetry of a dip in the non-pulsatile component.

Abstract: A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image.

Abstract: Methods and systems incorporating non-linear dynamic (NLD) analysis such as entropy or other complexity analysis monitoring continuous or evoked signals from a biological subject are presented, where such a system comprises of processing steps including: a) the combination of a biological signal evoked as a result of patient stimulation presented to a biological subject and a non-linear analysis method capable of capturing temporal changes in signal order or regularity; b) any combination of processed evoked or continuous central nervous or peripheral physiological mechanisms b) a means to generate a measure indicative of a patient's level of anaesthesia and consciousness depth (A&CD), sedation or sleep/wake state.

Abstract: Embodiments provide a computer implemented method of perceiving a pain intensity level and sensation, the method comprising: training, by a processor, a first machine learning model with a plurality of electronic medical records of different patients having a pain; deriving, by the processor, a second machine learning model for a particular patient from the first machine learning model, based on a medical history, all the speech, facial expressions and body language of the particular patient during each clinic visit; receiving, by the second machine learning model, new speech, new facial expressions, and new body language from the particular patient; and generating, by the second machine learning model, a pain intensity level and sensation of the particular patient based on the new speech, new facial expressions, and new body language.

Abstract: Embodiments herein relate to systems, devices and methods for managing pharmacological therapeutics and aspects of the same. In an embodiment, a hearing assistance device can include a control circuit, an electroacoustic transducer for generating sound in electrical communication with the control circuit, a power supply circuit in electrical communication with the control circuit, and a sensor package in electrical communication with the control circuit. The control circuit can be configured to evaluate a signal from at least one of the sensors of the sensor package to detect administration of a therapy or receive data indicating that administration of a therapy has taken place. The control circuit can also be configured to record an instance of a detected medication administration event along with a timestamp. Other embodiments are also included herein.

Abstract: Heart valves are provided, comprising a heart valve and a plurality of sensors.

Abstract: A wearable defibrillator includes garment configured to be worn by a patient, treatment electrodes configured to apply electric current to the patient, and an alarm module configured to provide audio, visual, and haptic notifications. The notifications are configured to indicate that an electric current will be administered imminently, and prompt the patient to provide a response input. The wearable defibrillator includes a motion sensor configured to detect motion and a lack of motion of the patient, and a controller in electrical communication with the alarm module and the motion sensor. The controller is configured to monitor for the response input, cause administration of the electric current to be delayed or cancelled if the response input is received and motion of the patient is detected, and cause administration of the electric current to be delivered if no response input from the patient is received and a lack of motion is detected.

Abstract: Improved methods and systems are disclosed for a physiotherapeutic device that may enable correction and/or maintaining of postural stance for individuals. A method includes storing a plurality of data pairings in a database. Each pairing may represent an association between at least one sensor datum and a physical state. The method may further include receiving a transmitted sensor datum. The transmitted sensor datum may derive from a sensor that is associated with a garment and may be received at a facility remote to the garment. The method may also include searching the plurality of data pairings in the database for a physical state associated with the transmitted sensor datum, sending an alert indicating the physical state associated with the transmitted sensor datum, and making a posture support adjustment to the garment based at least in part on receipt of the alert.

Abstract: The present disclosure provides a joint function monitoring device. The joint function monitoring device comprises a bottom base capable of being removably attached to a hinge of an assistive device, a shaft comprising a central pan coupled to the bottom base, and a distal part, a first sensor coupled to the central part of the shaft for monitoring a rotation angle of the shaft, and a belt module coupled to the distal pan of the shaft and capable of being removably attached to a support assembly of the assistive device. A length of the belt module is adjustable.

Abstract: Sensor system comprising a frame supporting a force-sensing tip arranged to generate a signal based upon a force applied by said force-sensing tip to a material to be tested, the system further comprising: an input drum mounted in said frame such that it can rotate about an input axis of rotation; an output lever supported by said frame by means of an output revolute joint defining an output axis of rotation; wherein said force-sensing tip is mounted on said output lever such that said force-sensing tip is arranged to be brought into contact with a material to be tested; and wherein said sensor system comprises a mechanical transmission arranged to kinematically link said input drum to said output lever such that a rotation of said input drum about said input axis of rotation causes said output lever to pivot in an oscillatory manner about said output axis of rotation.

Abstract: An ocular cranial nerve monitoring system (OCNMS) that provides continuous measurement of pupillary reactivity in the eye. The system features a sensor component that produces a stimulating light and a recording light and records reflected recording light so as to calculate pupillary diameter and response to stimulation as measured by latency, velocity, and/or amplitude. This system of the present invention may be used for indirect assessment of the 2nd and 3rd cranial nerve (CN 2, CN3) pathways and/or intracranial pressure in patients and may be used intraoperatively. The data obtained from this system may allow for immediate corrective actions, which may help prevent permanent deficits and improve patient safety and surgical outcomes. In some instances, the system may help avoid unnecessary or invasive procedures (e.g., catheters inserted for intracranial pressure monitoring).

Abstract: An analyte sensor cover is disclosed comprising a sensor cover including a top side, a bottom side, and an aperture. The bottom side includes a recessed portion dimensioned to at least partially receive an in vivo analyte sensor. An adhesive component adheres to the top side of the sensor cover and at least partially to the skin of a user to retain the in vivo analyte sensor in a suitable position.

Abstract: Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.

Abstract: A method comprising executing a prescription digital therapeutic configured to treat symptoms associated with migraines experienced by a patient.

Abstract: This disclosure provides systems, methods and apparatus for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor. The system may include a display device with at least one input device. In response to movement of or along the input device, the display device may change a glucose data output parameter and update an output of the display device using the changed output parameter.

Abstract: An x-ray examination arrangement includes an x-ray radiation source arranged at a source position, at least two x-ray detectors having active detector areas and being arranged such that the active detector areas capture different solid angle ranges with respect to x-ray radiation produced by the x-ray radiation source and emanating from the source position, and a control device configured to calculate a projection onto a virtual detector plane based on radiographs respectively captured by the at least two x-ray detectors and spatial poses of the at least two x-ray detectors relative to the source position, and provide a combined radiograph for the virtual detector plane based on the projection. In addition, a method for operating the x-ray examination arrangement and a computed tomography device are provided.

Abstract: Disclosed is a patient positioning assembly for orientating a patient with respect to a radiation source. The patient positioning assembly includes a translatable member movable in a vertical direction between a vertically downwards first position and a vertically upwards second position. The patient positioning assembly further includes a patient support assembly mounted to the translatable member and adapted to rotate relative to the translatable member about a vertical axis. The patient support assembly is configurable between a first orientation, which sustains the patient in a seated position, and a second orientation, which sustains the patient in a generally standing position.

Abstract: A method is provided for determining a relative position of an object in relation to an x-ray imaging apparatus for creating an x-ray and a recorded image. The method includes brining an object in a ray path of the x-ray into a first position. The x-ray is created with a first focus point by an x-ray source and a first recorded image of the object in the first position is created by the x-ray focused on a first focus point. In the first recorded image, at least one defined geometry in and/or on the object is imaged. A measure for a change in the focus point towards a second focus point is undertaken at the x-ray source. The x-ray with the second focus point is created by the x-ray source and a second recorded image of the object in the first position is created by the x-ray focused on the second focus point. In the second recorded image, the at least one defined geometry is imaged.

Abstract: A radiation finder tool assists in locating tissue of interest within a patient. The radiation finder tool includes a body and a plurality of radiation detectors. The body has a distal end, a proximal end. A lengthwise axis of the radiation finder tool extends between the proximal end and the distal end of the body. The plurality of radiation detectors is oriented serially along the lengthwise axis, e.g., stacked one after the other along the lengthwise axis. Each radiation detector of the plurality of radiation detectors has a different field of view for radiation detected by that radiation detector. Each field of view of the plurality of radiation detectors has the lengthwise axis at its center.

Abstract: The present invention relates generally to X-ray detectors and more particularly to a system and a method for integrating an anti-scattering grid with scintillators to significantly enhance the performance of flat panel X-ray detector. In particular, the performance of a flat panel X-ray detector may be enhanced by photon counting detector pixels configured underneath the septa of a 2D antiscatter grid.

Abstract: An imaging system that is configured to automatically obtain and provide two and three-dimensional digital images of various types of objects (e.g., tissue specimens, animals, electrical devices, etc.) for use in analysis thereof in a manner free of manual repositioning of the objects between images and free of movement of an electromagnetic radiation source and detector within or relative to a cabinet housing of the system.