Abstract: There is provided an intravascular blood pump for insertion into a patient's heart. The blood pump comprises a slotless permanent magnet motor contained within a housing, the motor having p magnet pole pairs and n phases, where p is an integer greater than zero, and n is an integer ?3. The motor comprises a stator extending along a longitudinal axis of the housing and having 2np coils wound to form two coils per phase per magnet pole pair. The stator comprises inner and outer windings each comprising np coils electrically connected such that the current flowing through the coils is in the same direction, the coils of the outer winding arranged on an outer surface of the coils of the inner winding.

Abstract: A ventricular assist device includes a housing assembly with a pressurized inner chamber, an impeller, an electric motor and a distance sensor. The electric motor includes a controller, a stator and a rotor. The stator and the controller are located in the housing assembly, outside of the pressurized inner chamber and are electrically coupled. The impeller and the rotor are located in the pressurized inner chamber and fixedly coupled. The distance sensor is located in the housing assembly, outside of the pressurized inner chamber and electrically coupled to the controller. The distance sensor senses a distance value of the rotor to a cavity wall of the pressurized inner chamber, and further transmits the distance value to the controller. The controller controls a magnetic force between the stator and the rotor according to the distance value, so as to control a suspension and rotation of the rotor.

Abstract: A blood pump system includes a catheter, a pump housing disposed distal of a distal end of the catheter, a rotor positioned at least partially in the pump housing, a controller, and an electrode coupled a distal region of the blood pump. The electrode can be used to sense electrocardiogram (EKG) signals and transmit the signals to a controller of the blood pump. The operation of the blood pump can be adjusted based on the EKG signal and on cardiac parameters derived from the EKG signal. Further, the controller can determine a need for defibrillation or pacing of the patient's heart based on the signal and can administer treatment with electrical shocks to the heart via the electrode coupled to the blood pump. The use of an electrode with a blood pump already in place in the heart allows for more efficient and safer treatment of serious cardiac conditions.

Abstract: An optical sensor assembly for use in a blood pump assembly comprising a visor affixed to a pump housing of the blood pump assembly. A support jacket is in contact with an inner surface of the visor, and defines a cavity in which an optical sensor is disposed. A silicone composition is introduced into the cavity, where it cures. The silicone composition within the cavity protects the optical sensor, and the support jacket prevents the overflowing of the silicone composition and contamination of the visor. The silicone composition comprises a silicone component and a plasticizer with a silicone to plasticizer ratio selected to provide one or more of the desired rigidity, tackiness, adhesion strength, viscosity, shelf life, pot life, and curing properties. The silicone composition may comprise more than one silicone component. A method of manufacturing the optical sensor assembly and the silicone composition.

Abstract: A method of controlling a blood pump having a predefined hydraulic performance including at least from the group consisting of estimating and measuring an instantaneous flow rate during operation of the blood pump at a predetermined rotational speed of an impeller of the blood pump, the instantaneous flow rate including a plurality of flow rate data points. The plurality of flow rate data points define a trajectory around at least one from the group consisting of an operational point of a predefined pressure-flow curve associated with the predetermined rotational speed of the impeller of the blood pump and a target operational point of a target pressure-flow curve different than the predefined pressure-flow curve. The predetermined rotational speed of the impeller is adjusted until the plurality of flow rate data points define a predetermined trajectory around at least one of the operational point and the target operational point.

Abstract: A rotary pump housing having a cylindrical bore, a pumping chamber and a motor stator including an electrically conductive coil located within the housing and surrounding a portion of the cylindrical bore. A rotor has a cylindrical shaft with an impeller and one or of magnets located within the shaft that are responsive to the motor stator to drive actuation of the rotor. The housing bore is closely fitted to the outer surface of the shaft forming a hydrodynamic journal bearing with an annular clearance defining a leakage flow path. One or more of radial or axial thrust bearings may be provided to provide rotation stability to the rotor and flow within the leakage flow path. The relative orientation of positions of the inflow, outflow, and leakage flow paths may be varied within the pump, such as to accommodate different intended methods for implantation and/or use.

Abstract: A blood pump comprises a pump casing having a blood flow inlet and a blood flow outlet, and an impeller arranged in said pump casing so as to be rotatable about an axis of rotation. The impeller has blades sized and shaped for conveying blood from the blood flow inlet to the blood flow outlet. The blood pump also has an outflow cannula having an upstream end portion, a downstream end portion and an intermediate portion extending between the upstream end portion and the downstream end portion. The upstream end portion of the outflow cannula is connected to the pump casing such that blood is conveyed from the blood flow outlet of the pump casing into and through the intermediate portion of the outflow cannula towards the downstream end portion of the outflow cannula, wherein the downstream end portion has a blood flow outlet through which blood can exit the outflow cannula.

Abstract: A dialysis system is described having components for facilitating a health-enhanced environment in the vicinity of a dialysis machine in the home. The health-enhancing components may include air improvement components and potable water supply components integrated and/or otherwise incorporated into the home dialysis machine. By incorporating the ability for monitoring, cleaning, and controlling air and/or water quality into the home dialysis machine, the dialysis machine is no longer just a source of life for the dialysis patient but also a source of health enhancement for the entire household. The system may further display and/or remotely communicate information concerning the dialysis treatment, the air quality and the potable water quality corresponding to operation of the dialysis machine in the home environment.

Abstract: An extracorporeal therapy system includes: (i) a dialysis fluid circuit including dialysis fluid preparation structure to prepare a dialysis fluid for treatment, the dialysis fluid circuit including a fresh dialysis fluid pump, a used dialysis fluid pump, and at least one filter for purifying the dialysis fluid; (ii) a blood circuit including a blood filter for use during the treatment; (iii) a blood pump operable to pump blood through the blood circuit and blood filter; (iv) a source of disinfecting fluid; and (v) a control unit operable with the dialysis fluid preparation structure and the blood pump, the control unit programmed to cause the disinfecting fluid to be delivered to and located for a duration at an area of the dialysis fluid circuit having the at least one purifying filter, and wherein during the duration the disinfecting fluid is precluded from contacting at least the fresh dialysis fluid pump.

Abstract: Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments, may include a dialysis machine for transferring dialysate to a patient from a dialysate bag, and a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient. The dialysate may flow from the dialysate bag through the warmer pouch for pumping into the patient via tubing. A filter may be coupled to the warmer pouch, and the filter may be configured to filter out air content from the dialysate.

Abstract: A spectroscopic detection system includes a sensor configured to reflect light of a first wavelength associated with a presence of a reference substance on the sensor and configured to reflect light of a second wavelength associated with a presence of a monitored substance on the sensor, wherein the monitored substance flows to the sensor from a circulating fluid. The spectroscopic detection system further includes a detector that has first and second channels for respectively receiving the light of the first and second wavelengths reflected from the sensor and one or more processors in electrical communication with the detector and configured to identify an excess condition of the monitored substance with respect to the circulating fluid based on a ratio of a second amount of the light of the second wavelength received at the detector to a first amount of the light of the first wavelength received at the detector.

Abstract: The present invention relates to an apparatus for regenerating a dialysis solution, wherein the apparatus has a first circuit and a second circuit, with the first circuit having a container for receiving the consumed dialysis solution, the primary side of a filter connected downstream of the container, and a return line from the primary side of the filter into the container, with the filter being configured to prepare purified water from the consumed dialysis solution, and with the second circuit having the secondary side of the filter, the dialyzate side of a dialyzer, and a return line from the dialyzate side of the dialyzer into the container. The present invention further relates to a method of regenerating a dialysis solution.

Abstract: A method for operating a dialysis machine to conduct a dialysis treatment on a patient (e.g., a peritoneal dialysis machine) may include transferring dialysate from a first bag, and automatically determining the dialysate from the first bag has completely transferred. After determining the dialysate has completely transferred from the first bag, switching from the first bag to a second bag of dialysate. The method may further include transferring dialysate from the second bag in response to the detection of the completed transfer of the first bag, and automatically determining the dialysate from the second bag has completely transferred. The method may further include determining if the respective first or second bag has completely transferred by comparing a dialysate bag volume transferred to the patient to a detected volume of the respective first or second bag. Systems with dialysis machines for performing such a method are disclosed as well.

Abstract: Dialysis machines and methods for operating dialysis machines (e.g., peritoneal dialysis machines) may include delivering dialysate to a patient and detecting a temperature of a volume of the dialysate, an air content of the dialysate volume, or another condition, or combinations thereof, wherein the detected temperature of the dialysate volume is compared to a predetermined maximum temperature, the detected air content of the dialysate volume is compared to a predetermined maximum air content and the detected other condition generates a signal. The volume of dialysate may be diverted in response to the detected temperature exceeding the predetermined maximum temperature, the air content exceeding the predetermined maximum air content, or the other condition generated signal, or combinations thereof.

Abstract: A blood purification apparatus that includes a blood circuit including an arterial blood circuit and a venous blood circuit and having a flow route that allows a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a blood purifier connected to a proximal end of the arterial blood circuit and to a proximal end of the venous blood circuit and that purifies the blood flowing through the blood circuit; an air-trap chamber connected to the blood circuit and that traps bubbles contained in liquid flowing in the flow route of the blood circuit; and a blood pump provided to the arterial blood circuit and being capable of delivering the liquid within the blood circuit.

Abstract: The invention relates to a device and a method for monitoring access to a patient for a device by means of which a liquid is withdrawn from the patient and/or supplied to the patient via a flexible line, in particular for monitoring vessel access during extracorporeal blood treatment, in which blood of a patient is withdrawn from the patient via a flexible arterial line having an arterial puncture cannula and supplied to the patient via a flexible venous line having a venous puncture cannula. The monitoring device 20 has a line guide 21 for loosely guiding a line segment 7A of the flexible line 7. The invention is based on detecting a change in situation of the loosely guided line segment 7A due to tension applied if the puncture cannula slips out, it being concluded that incorrect vessel access is occurring if the situation of the line segment changes. Since only changes in situation are monitored, even slight applied tensions are already sufficient for reliably detecting incorrect vessel access.

Abstract: The disclosure provides a method of placing a cardiac drainage cannula into a patient's heart. In some embodiments, the method comprises the steps of (a) inserting the cannula percutaneously into an internal jugular vein, (b) advancing the cannula through the internal jugular vein and into the right atrium of the heart, and (c) advancing the cannula through the atrial septum into the left atrium of the heart. Further aspects of the disclosure provide a method of draining blood from the left atrium or left ventricle of a patient's heart using a cardiac drainage cannula. The disclosure also provides a cardiac drainage cannula and a mechanical circulatory support system.

Abstract: The present invention discloses a self-sealing cannula and methods of its use. The self-sealing cannula can be minimally invasively placed into the heart for drawing and/or returning blood with a self-sealing function at the interface of the blood access site. The disclosed cannula can be implemented as a single lumen cannula or a double lumen cannula, which can be used with ventricular assist devices for heart support or pump-oxygenators for ECMO and respiratory support. Through a self-sealing mechanism fixed on the ventricular wall or atrial wall, a cannula body is attached to the self-sealing fixture and blood is drawn into the lumen via an external pump and returned to the circulation system through a separate cannula. In the case of the double lumen cannula embodiment, the blood will be drawn into the drainage lumen of the double lumen cannula and returned through an infusion lumen at the desired location.

Abstract: A system for cleansing wounds with a fluid jet includes a pressure pump (900) for generating a fluid jet, a handpiece body (200) with a nozzle (204) for emerging the fluid jet, a fluid line (90) connecting the pressure pump (900) with the handpiece body (200), an adapter (700) holding a porous body (510), the adapter (700) being releasably connected to the handpiece body (200). The adapter (700) and the porous body (510) comprise a free inner space (770, 570) into which the fluid jet emerges when leaving the nozzle (204). The adapter (700) is at least partially transparent, thereby enabling a view into the inner space of the adapter and the porous body. The system according to the invention combines the advantages of cleansing by a fluid jet with the advantages of mechanical cleansing and, at the same time, provides effective protection against aerosols.

Abstract: A carrying case for an add-on device of a medicament delivery device is presented where the carrying case has an add-on device holder configured to hold the add-on device, an energy storage device, and a charging device configured to wirelessly electrically charge the add-on device from the energy storage device when the add-on device is held by the add-on device holder.

Abstract: This document discusses, among other things, an apparatus comprising a pump configured to deliver a fluid, a wireless communication port, a controller, and a housing to enclose the apparatus. The controller is configured to communicate with a second device via the communication port using an open standard wireless communication protocol. The housing includes a mechanical coupling to slidably engage the second device which includes a second wireless communication port. Slidably engaging the second device positions the first and second communication ports opposite each other to allow communication via the first and second communication ports when slidably engaged.

Abstract: An automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product. The drug container includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the insertion needle. The automatic injection device further has a drive system configured to cause linear movement of the plunger to force the pharmaceutical product into the fluid path. The drive system has a driving element and a movable element. The automatic injection device additionally has electronics configured to provide a signal to the drive system to move the plunger. The movable element has an outer magnet at least partially surrounding the drug container and an inner magnet inside the drug container.

Abstract: An electronic injector including a needle insertion assembly configured to move a needle in an insertion direction from a first needle position where the needle is above the surface of a patient's skin to a second needle position where the needle pierces the patient's skin. The injector further includes a member mechanically coupled to the needle and configured to move when the needle. The injector further includes an optical detector having a generally planar detection surface and configured to detect movement of the member based on a change in a transverse projection of the member onto the detection surface and output a signal based on the change in the transverse projection. Additional, a processor is configured to determine the position of the needle based on the output signal, and the transverse projection of the member changes when the needle moves.

Abstract: An injection device configured for attachment to the skin of a patient using an adhesive layer includes a release liner covering the adhesive layer thereby preventing skin attachment. The release liner comprises a sheet of material where a first surface contacts the adhesive layer, and an aperture defining a passage for a film connected to a first sterile barrier film located within the injection device. An end of the film is connected to a second surface of the sheet of material that is opposite to the first surface, and the release liner is covered by a strengthening sheet connected to the second surface and covering the aperture and the end of the film.

Abstract: An injection device configured for attachment to the skin of a patient includes a housing and a skin adhesive layer attached to an external surface of the housing for attaching the injection device to the skin of a patient. A release liner covering the skin adhesive layer prevents the injection device from attaching to the skin. A film with one end connected to a surface inside of the housing forms a removable sterile barrier and the other end connected to an external surface of the release liner without contacting the skin adhesive layer. The housing, skin adhesive layer and release liner each include a notch defining a passage for the film so that the second end of the film can extend from the interior to the exterior of the housing.

Abstract: A patch delivery device includes a bottom housing part, a delivery element for subcutaneous delivery of a liquid to a patient, an adhesive patch for attaching the bottom housing part to the skin of the patient, a capacitive sensor with an electrode configuration including a plurality of skin contact sensitive electrodes, and a release liner covering a patient-side adhesive layer of the adhesive patch prior to adhering to the patient's skin. The release liner includes an electrically conductive area extending over at least a portion of the electrode configuration of the capacitive sensor before being removed from the adhesive patch. Providing the release liner with a conductive area gives rise to a discernible change in capacitive response of the sensor electrodes upon release liner removal that enables sensing a removal of a release liner covering a patient-side adhesive layer prior to attachment to the skin of a patient.

Abstract: A surgical fluid management system includes a console and a cassette for delivering fluids to a surgical site. The console has a pump rotor and a pressure-sensing membrane. The cassette has a cassette housing, a flexible fluid delivery tube in the housing. The flexible fluid delivery tube has a lumen configured to interface with the pump rotor and to deliver a flow of fluid from a fluid source as the rotor is rotated. A pressure-transmitting membrane is located in a wall of the cassette housing and in fluid communication with said fluid delivery lumen. The pressure-transmitting membrane flexes outwardly in response to a positive pressure in the lumen and flexes inwardly in response to a negative pressure in the lumen. The pressure-transmitting membrane detachably adheres to or presses against the pressure-sensing membrane to cause the pressure-sensing membrane to move in response to pressure changes in the flexible fluid delivery tube.

Abstract: The present disclosure relates to an indicator device which comprises one or several plungers inside an elongated cavity. Said indicator device, is intended to provide to the user at least one information related to the current status of a delivery system. The indicator device comprises at least one movable element configured to reach pre-determined positions in response to the status of the delivery system.

Abstract: A fluid management and medical device system may include a fluid management system and a medical device. The fluid management system may include a pump configured to pump fluid to the medical device and a processing device configured to control the pump to maintain a target fluid flow range. The medical device may include an elongate shaft in fluid communication with the pump of the fluid management system, a pressure sensor, and a workstation in electronic communication with the pressure sensor and the processing device of the fluid management system. The processing device may be configured to adjust a fluid flow rate based on data received from the pressure sensor of the medical device and configured to verify the medical device is in a patient's body prior to adjusting the fluid flow rate based on the data received from the pressure sensor.

Abstract: A treatment system configured to treat a disease using a first therapeutic fluid, the treatment system including a base housing, a first reservoir configured to store a first therapeutic fluid disposed within the base housing, a first plunger disposed within the first reservoir, a first rotatable shaft member configured to rotate within the base housing, and a first flexible member having a first end coupled to the first plunger and a second end coupled to the first rotatable shaft member, wherein the first rotatable shaft member is configured to shorten a length of the first flexible member to deliver the first therapeutic fluid from the first reservoir.

Abstract: A device captures images of a plurality of objects, such as a bottle and a syringe, for the secure production of medicinal preparations. The device includes at least one pair of image capturing cameras, arranged one facing the other; one reflective element for each of the cameras; and the two reflective elements of the same camera pair being arranged between the cameras and each oriented so as to reflect, in the direction of the associated camera, images of a production area of a medicinal preparation. The image capture device additionally includes: a stationary part formed by positioners that are designed to be secured against an enclosure of the medicinal preparation production area, a base which is intended to be secured to the stationary part, and a half-baseplate which is mounted such that it can rotate relative to the base, with the half-baseplate carrying at least one of the cameras.

Abstract: A medicament delivery device is presented for administering a therapeutic substance from a multi-chamber cartridge. The medicament delivery device performs a mixing process to create the therapeutic substance for delivery within the multi-chambered cartridge, where the delivery device includes a distal part comprising a dose setting mechanism having a housing, a dose setting knob, an injection button, a piston rod capable of moving axially along the longitudinal axis of the housing during dose delivery, and a return ring configured to reset the piston rod to a starting position. The delivery device also includes a proximal part comprising a cartridge holder configured to accept a multi-chambered cartridge, where the cartridge holder comprises a screw driven sleeve configured for attachment to the distal part and where rotation of the screw driven sleeve performs a medicament mixing process within the multi-chambered cartridge.

Abstract: A generally planar micro injector with a securing lanyard is disclosed. The micro injector is constructed of an elastic ampoule with a flexible actuation area affixed to a thin base unit through which an injector needle is plumbed. The micro injector is secured to the hand with an adhesive layer and an affixed securing lanyard.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.

Abstract: A single-handed syringe may be used in injection and in aspiration for stable and consistent single-handed use. The syringe includes a hollow cylinder body, which has a front tip that the aspirated materials pass through toward/from a cylinder cavity. A rear plunger handle and a front plunger handle, in combination with a straight external prominence formed longitudinally along an outer surface of the cylinder body permits ease, accuracy, and precision of plunger movement during aspiration and injection functions.

Abstract: A syringe including an injection syringe body and a syringe handle, configured to cooperate with one another in order to ensure a locking function between the injection syringe body and the syringe handle. The injection syringe body includes a longitudinal hub including at least one female or male retaining element, and a protective sheath moveable along said longitudinal hub and able to cover in a retracted position the at least one retaining element of the longitudinal hub. The syringe handle includes at least one male or female retaining element intended to cooperate with the at least one female or male retaining element of the longitudinal hub, ensuring a retaining function, the cooperation being named locking position. The syringe further includes at least one blocker, the at least one blocker ensuring a radial holding function when the retracted and the locking positions are both engaged.

Abstract: A syringe system, including a plunger, a microcontroller, a battery, and a coil. The syringe barrel having a proximal end, a distal end, and a cylindrical sidewall defining a longitudinal axis, the cylindrical sidewall extending longitudinally between the proximal and distal ends, the sidewall having an exterior surface and defining an internal volume, the plunger being positioned between the proximal and distal ends of the syringe barrel and being movable within the internal volume with respect to the syringe barrel in the longitudinal direction. The syringe barrel further includes a label disposed on the sidewall and having at least two conductive strips extending in a non-parallel direction with respect to the longitudinal axis and having unique lengths. The microcontroller is configured to determine a position of the plunger with respect to the syringe barrel by measuring a current induced in the coil by the at least two conductive strips.

Abstract: Syringe assemblies are provided including a partially pre-filled syringe barrel and a plunger rod that incorporates one or more retention elements on the plunger rod that prevents solution from entering a non-sterile area of the syringe when the plunger rod is pulled back. Methods to manufacture a sterilized partially-filled pre-fill syringe assembly are also disclosed.

Abstract: The present invention concerns an apparatus (1) for measuring and recording the remaining quantity of medicament in a medicament dosing device (2). The apparatus (1) has a location where the medicament dosing device (2) can be inserted. Combined with that location the apparatus (1) has equipment for measuring and analysing. The apparatus is characterised in that this equipment for measuring and analysing comprises a contact image sensor (3) combined with that location for the medicament dosing device, and a software in connection with the contact image sensor. In addition the object of this invention is the corresponding method for measuring and recording the remaining quantity of medicament in a medicament dosing device (2).

Abstract: A device (1) for monitoring the state of an injection applicator comprising an energy source (10) and the following electronic components: an accelerometer (5), a time measuring means (6), a temperature measuring means (7), a processing unit (8) connected to a system adapted to store, process and transfer data, said system including: the time measuring means (6), the accelerometer (5), the temperature measuring means (7) and a memory (9), a user interface (4) connected to the processing unit (8) for presenting information based on the data transferred by the processing unit (8), said monitoring device (1) being connected to a control member (3) of the applicator, and wherein said monitoring device (1) is adapted to operate in a sleep mode and in an active mode, and is further adapted to detect by means of the accelerometer (5) at least a first action and a second action, the first action being related to taking said monitoring device (1) out of the sleep mode and putting it into the active mode, and the secon

Abstract: An assembly comprising a drug delivery device and an add-on device adapted to be releasably mounted thereon, the drug delivery device comprising a rotatable dose setting member with an outer surface and at least one axially oriented drive groove. The add-on device comprises a drive portion adapted to be mounted in engagement with the dose setting member and comprises a drive structure adapted to engage a drive groove and being biased in a radially inwards direction. This arrangement allows the drive structure to rotationally slide on the dose setting member outer surface and into engagement with the drive groove(s).

Abstract: A drive-control system for an injection device for delivering settable doses of a pharmaceutical substance contained in a cartridge, including a tubular housing body having a longitudinal axis, a proximal end and a distal end connectable to the cartridge enclosure, a helical spring contained in the housing body and a piston rod moveable towards the distal end and blocked in translation towards the proximal end. The housing body includes a control sleeve on which the spring is mounted, which rotatable around the axis, and a setting sleeve translatable along the axis. Rotation of the control sleeve in a first direction combined with compression of the spring causes the setting sleeve to be translated towards the proximal end of the housing body, and extension of the spring causes the setting sleeve to be translated towards the distal end of the housing body and the control sleeve to be rotated in a second direction and the piston rod to be pushed towards the outside of the housing body.

Abstract: The present disclosure relates to a dosage measurement system for a medicament delivery device. The medicament delivery device comprises a medicament reservoir, a lead screw and a drive sleeve. The drive sleeve is rotatable to axially displace the lead screw relative to the drive sleeve to dispense medicament from the medicament reservoir. The dosage measurement system comprises a sensor unit and a processor. The sensor unit is configured to measure rotation of at least one of the drive sleeve and lead screw. The processor is configured to determine a dosage dispensed from the medicament reservoir based on the measured rotation of said at least one of the drive sleeve and lead screw.

Abstract: A medical injection device for supporting a medical container comprising a barrel and a needle tip extending from a distal end of the barrel, comprising: safety shield, first ring configured to be coupled to the medical container and configured to be biased in a proximal direction relative to the safety shield from an injection position in which a needle tip extends out of the safety shield to a safety position in which the needle tip is covered by the safety shield, and second ring rotatably movable relative to the first ring between locking position wherein the second ring maintains the first ring in the injection position and an unlocking position wherein the second ring releases the first ring thereby allowing the first ring to be urged into the safety position.

Abstract: A fluid injector system has at least one reciprocally operable piston having a piston head, and a plunger engagement mechanism associated with the piston head. The plunger engagement mechanism has a cam sleeve disposed within the piston head and movable relative to the piston head, the cam sleeve having one or more tracks defining a cam surface. The plunger engagement mechanism further has an actuator operatively connected to the cam sleeve for moving the cam sleeve relative to the piston head, and one or more pins disposed within the cam sleeve. The one or more pins are movable within the one or more tracks with movement of the cam sleeve between a first or withdrawn position, wherein the one or more pins are radially withdrawn into the piston head and a second or extended position, wherein the one or more pins protrude radially outward relative to an outer surface of the piston head.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: A system with a needle head that attaches to a syringe assembly. The syringe assembly contains a barrel and a plunger. The plunger has a bore opening that is accessible from within the barrel. A tubular spacer is disposed within the barrel. The tubular spacer defines a central opening. The needle head has a needle that extends from a needle base. The needle base extends into the central opening of the tubular spacer. A plug is provided that blocks access to the needle. The plug is displaced out of the central opening of the tubular spacer and into the opening in the plunger as the plunger contacts and displaces the tubular spacer in the barrel. As the plug is displaced from the tubular spacer, the plug transfers into the bore opening within the plunger. This enables the plunger to press flush against the tubular spacer.

Abstract: A needle and syringe system, wherein a needle head is attached to a syringe assembly. The syringe assembly includes a syringe barrel and a plunger rod with a plunger head. A needle base is affixed to the syringe barrel. A tubular cavity is formed in the needle base and a post extends through the tubular cavity. A needle extends through the post. A spacer is provided. The spacer is displaced into the tubular cavity within the needle base as the plunger head is advanced within the syringe barrel. A protective cover is disposed about the needle base. The spacer moves the protective cover between a first position and a second position as the spacer is displaced into the tubular cavity. As the protective cover moves between positions, the protective cover surrounds the needle and prevents the needle from causing any inadvertent needle stick injuries.

Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula. The needle cannula or other device can be received in a capsule and/or other container. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.