Abstract: A needle hub assembly for a pen needle includes a needle hub, a cannula or needle coupled to the needle hub, a retractable and compressible sleeve covering at least one end of the cannula, and an outer cover. The outer cover encloses the needle hub and the retractable sleeve. The retractable sleeve is coupled to the hub to cover the end of the cannula where the sleeve can pass through or can be pierced by the cannula and the sleeve retracts axially on the cannula. The sleeve is resilient and returns to an original configuration when an insertion force is released. The needle hub can have a first sleeve to cover a patient end of the cannula, and second sleeve to cover a non-patient end of the cannula where the sleeves retract onto the cannula or hub and expand to the original configuration to cover the ends of the cannula.

Abstract: Improved apparatus for use with medication in fluid form, which is particularly beneficial for medications having a relatively high viscosity, and method(s) of manufacturing and/or method(s) of using same. The disclosed syringe adapter has an opening that is relatively large, as compared to a conventional needle, and thus affixing the disclosed syringe adapter to a syringe improves syringeability of higher-viscosity medications. In some embodiments, the syringe adapter will be replaced with a needle prior to injecting the medication, while in some other embodiments, the needle is affixed to the in-place syringe adapter for the injection. In yet other embodiments, the needle is affixed to a needle holder that, in turn, is affixed to the in-place syringe adapter for the injection.

Abstract: The present invention relates to a recording unit arranged to be connected to a medicament delivery device, which recording unit comprises a generally elongated housing having dimensions so as to enclose at least a distal part of the medicament delivery device, the recording unit comprising a recording mechanism provided with an electronic circuit and arranged at a distal end inside said housing, said electronic circuit comprising an activation element operably arranged to activate said electronic circuit when said medicament delivery device is inserted in said housing, said electronic circuit comprising sensor elements capable of sensing status changes of said medicament delivery device during use.

Abstract: A capsule for a heat-not-burn (HNB) aerosol-generating device may include a first frame, a second frame, a first heater, a second heater, and/or an aerosol-forming substrate. The first frame has a first interior face and a first exterior face. In addition, the first frame defines a first opening. The first heater may be secured to the first frame so as to cover the first opening. The second frame is connected to the first frame. The second frame has a second interior face and a second exterior face. Furthermore, the second frame defines a second opening. The second heater may be secured to the second frame so as to cover the second opening. The aerosol-forming substrate may be between the first heater and the second heater.

Abstract: The present application relates to an electronic vaporizer device, an electronic vaporizer device body, and an operation method. The electronic vaporizer device body is used in combination with an electronic vaporizer, the electronic vaporizer device body including: a power supply configured to supply power; an airflow sensor configured to detect an airflow change and output first level information; a main control circuit electrically connected to the airflow sensor and configured to control, according to the first level information, the power supply to supply or interrupt power to the electronic vaporizer.

Abstract: An aerosolization conduit assembly is provided for drug-delivery systems. The aerosolization conduit assembly comprises an outer tube; an inner tube disposed in the outer tube, having outer supporter openings formed on a side of wall of the inner tube; a liquid storage chamber formed between the inner tube and the outer tube; a liquid inlet opening on a side wall of the outer tube; and an atomizing member having an end arranged in the one or more outer supporter openings. The inner tube comprises parallel tubes extending from the atomizing member and feeding a double-barrel, ricocheting vortex-effect mouthpiece. The mouthpiece cooperates with the parallel tubes to allow for increased adiabatic expansion and compression, thereby providing a less intense, more even experience to a practitioner of the electronic cigarette.

Abstract: An object of the present invention is to provide a powder preparation and the like suitable for selective administration to an olfactory region and the like. The object is achieved by a powder preparation for selectively administering an active ingredient to an olfactory region in a nasal cavity, the powder preparation comprising the active ingredient and having a bulk density of 0.1 to 0.5 g/cm3 and a Hausner ratio of 1.6 to 2.4.

Abstract: A respiratory treatment apparatus provides respiratory treatment with improved power management control to permit more efficient power consumption and power supply units, such as battery powered operation. In one embodiment, power management prioritizes the flow generator (104) over other accessories such as the heating elements (111, 135) of a humidifier (112) and/or a delivery tube. The flow generator may control operations of the heating elements as a function of a detected respiratory cycle. For example, the timing of operation of the heating elements may be interleaved with the portion of an inspiratory phase of the respiratory cycle to permit the flow generator to operate during a peak power operation without a power drain or with a lower power drain from these components. Operations of distinct sets of components of the system (e.g., different heating elements) may also be interleaved to prevent simultaneous peak power operations.

Abstract: A safety warning system for detecting the use of a heated humidifier with a heat and moisture exchanger in a respiratory circuit is described herein. The system comprises a heat and moisture exchanger defining at least a portion of the respiratory circuit, and configured to exchange air between a patient and a ventilator; and a temperature indicating element configured to provide an indication that the heat and moisture exchanger is used in combination with a heated humidifier based on the temperature differential between the air exchanged with the patient and the air exchanged with the ventilator in the respiratory circuit.

Abstract: A patient circuit of a ventilation system, such as a non-invasive open ventilation system, wherein the patient circuit comprises a nasal pillows style patient interface that incorporates at least one “Venturi effect” jet pump proximal to the patient. The patient circuit further comprises a pair of uniquely configured 3-way connectors which, in cooperation with several uniquely configured tri-lumen tubing segments, facilitate the cooperative engagement of the patient interface to a ventilator of the ventilation system.

Abstract: The present disclosure describes a system that automatically detects patient-ventilator asynchrony and trends in patient-ventilator asynchrony. The present disclosure describes a framework that uses pressure, flow, and volume waveforms to detect patient-ventilator asynchrony and the presence of secretions in the ventilator circuit.

Abstract: An oral care device for use during intubation. The device can include a first guard, a second guard, a first extension, a second extension, and a central pathway. The first guard can be configured for insertion into an oral cavity of a patient. The first extension and the second extension can each extend from the first guard and can together be configured to engage a dentition of a patient. The second guard can be configured to surround and engage an exterior of an oral cavity of the patient.

Abstract: An apparatus to remove liquid from a ventilation system can include a housing, a first port extending into an interior volume of the housing and a second port extending toward the first tube, into the interior volume, separated from the first port by a gap that is at least 5 mm in length, such that ventilating fluid transfers from the first port to the second while secretions and condensate escape through the gap, to be trapped in the housing. The first port joins with a ventilator. The second port joins with an intubation tube coupled to a tracheostomy or endotracheal tube. An extraction port is in a floor of the housing so that accumulated liquids in the housing can drain downward and out the extraction port, while minimizing positive end expiratory pressure loss in the ventilation system, and without exposing caregivers to biological material in the drained liquid.

Abstract: A medical device system and method including an endotracheal tube configured for insertion into a patients mouth or nose are disclosed. The endotracheal tube may include an outer cannula extending from a proximal end to a distal end configured to be positioned between in a patient's trachea. The outer cannula may include a lumen extending from a first opening defined in the proximal end to a second opening defined in the distal end. The endotracheal tube may further include an inner cannula removably positioned in the lumen of the outer cannula. The inner cannula may include a proximal end that extends outwardly from the first opening of the outer cannula, a distal end positioned adjacent to the distal end of the outer cannula, and a passageway extending through the distal and proximal ends of the inner cannula.

Abstract: A cannula for providing respiratory therapy to a patient includes a first nasal prong having a proximal end attached to a cannula body and a distal end for insertion into a nare of the patient. The first nasal prong defines a lumen for a flow of breathing gas from a source of breathing gas to the nare of the patient, and the first nasal prong has a variable geometry such that a cross-sectional area of the lumen at the distal end of the first nasal prong varies with a flow rate of the breathing gas. Varying the cross-sectional area of the first nasal prong lumen with the flow rate of the breathing gas enables the first nasal prong to maintain a high velocity flow to the nare for effective flushing of the patient's airway.

Abstract: A connector (100) for arranging at least one sensor at a ventilation system. The connector includes at least one basic body (103) for connection to at least one ventilation device, at least one pivoting element (101) for connection to a user, and at least one sensor mount (125) for at least one sensor. The at least one pivoting element (101) is connected directly and undetachably to the basic body (103) on a first side (115). The at least one pivoting element (101) is pivotable about at least one axis with respect to at least one part of the basic body (103) in order to protect the basic body (103) against pulling and compressive forces imparted by the user.

Abstract: A non-invasive ventilation system may include at least one outer tube with a proximal lateral end of the outer tube adapted to extend to a side of a nose. The at least one outer tube may also include a throat section. At least one coupler may be located at a distal section of the outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril. At least one jet nozzle may be positioned within the outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply. At least one opening in the distal section may be adapted to be in fluid communication with the nostril. At least one aperture in the at least one outer tube may be in fluid communication with ambient air. The at least one aperture may be in proximity to the at least one jet nozzle.

Abstract: A heat moisture exchanger (HME) having a rotatable bypass channel includes a rotating cylinder having a first port and an outer cylinder having a second port attached to the rotating cylinder. A half-cylinder shaped foam insert is configured within the rotating cylinder to heat and moisturize air moving through the HME. The cylinder is configured to create a rotational bypass to air using an angled diverter moving between the first port and second port such that the rotating cylinder can be moved between a position for engaging the foam insert and a bypass position for bypassing the foam insert.

Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

Abstract: An apparatus for the supply of humidified gases to a patient is disclosed that comprises a gases supply passage downstream of a humidified gases supply, and upstream of a patient in use, where at least one sensor is embedded in or located on the outside of the wall of the passage. In preferred forms the wall of the passage divides the sensor(s) from a flow of gases in the passage. In use, a controller receives an output of the sensor(s) and derives from the output of the sensor(s) an estimation of a property of gases flowing through the passage or provides a control output to the humidified gases supply according to the output of the sensor(s).

Abstract: Aspects of the present disclosure relate to systems for emitting light (e.g., substantially white light) with tunable circadian effects and substantially consistent color characteristics, and methods of making and/or operating the same. Certain embodiments described herein are systems comprising a plurality of light-emitting regions configured to emit light having certain circadian effects (e.g., melanopic ratio) and certain color characteristics (e.g., corrected color temperature (CCT), color rendering index (CRI)). According to some embodiments, the difference between the circadian effects of the light-emitting regions may be relatively large, and the difference between the color characteristics of the light-emitting regions may be relatively small. Each light-emitting region may comprise one or more light-emitting diodes (LEDs), each of which may be associated with one or more wavelength-converting materials (e.g., phosphors).

Abstract: Introduced are methods and systems for a sleep pod. An occupant of a sleep pod can have a personalized sleeping experience based on an analysis of biological signals, environmental characteristics, occupant history, and other factors.

Abstract: The present technology relates to an item cover for containing an aromatherapy component for providing an aromatherapy. The item cover includes an exterior and an interior including an inner lining. The interior receives a stuffed item. The item cover further includes at least one pocket for receiving at least one removeable insert comprising an aromatherapy component.

Abstract: Provided is a heart-rate control device capable of adjusting the heart rate of a subject to a desired value between a base heart rate and an active heart rate, such as a heart rate immediately after physical exercise.

Abstract: Systems and methods for providing a reinforced cannula for use in a blood pump assembly. The reinforced cannula comprises one or more thermoformed reinforced end portions. The thermoformed reinforced end portions may be stiffer than a medial portion of the cannula, allowing the medial portion of the cannula body to stretch and bend more readily than the cannula ends when the cannula is subject to an applied stress, reducing the stress and strain on the cannula ends.

Abstract: An embodiment of the present invention provides for an elongated medical device with a hypotube backbone running through the device, and a spiral lumen spiraled around the backbone along the length of the backbone. The backbone may be formed from a nitinol alloy for increased bendability without compromising axial stiffness. The device may also incorporate a jacket around the hypotube and spiral lumen formed using either melting, molding, bonding, or casting. The spiral lumen may be configured to accommodate a variety of uses, including actuation members (e.g., pull wires), tools, and means for aspiration, irrigation, image capture, and illumination. Additionally, the present invention provides a method for constructing an elongated medical device with a hypotube backbone running through the device, and a spiral lumen spiraled around the backbone along the length of the backbone.

Abstract: A cannula-catheter bonding method and apparatus can include a needle having a specifically configured connector end to reduce the risk of the connector end disengaging with an adapter (e.g., a catheter, a cannula, or a connector of a Huber needle assembly, etc.). The specifically configured needle connector end can be a formation, such as a barb, a bead, an annular structure, a rib, etc. The formation can be formed on the connector end, and may be elongated with a conical shaped nose leading to a base with a bottom. The formation can be used to prevent movement of the needle relative to the adapter. A method for producing the formation can include forming a mold for the formation in a plate, where the connector end can then be placed within the mold so that curable material can be disposed within the mold. Upon hardening of the curable material, the formation can take the shape of at least a portion of the mold.

Abstract: The disclosure relates generally to an extended use systems and devices for management of bladder function for people with urinary dysfunction. The system includes a catheter and a valve that can control fluid flow. The catheter can be placed inside the bladder using devices that facilitate insertion and extraction. The placement of the catheter can be done by a trained individual such as a patient, as well as a clinician, a nurse, or a caretaker. Once placed inside the bladder, the catheter can be fully-internal, meaning no portion of the catheter is visible from outside of the patient's body.

Abstract: The presently described catheter is an improved multi-function hypospadias catheter adapted to be urethrally inserted and secured within a patient's bladder using an attached internal crescent shaped retention balloon. The inverted crescent configuration of the balloon reduces the contact surface area between the balloon and a patient's bladder wall to reduce bladder spasms. The catheter is removed from the patient (when needed) via deflation of the crescent shaped balloon, which deflates completely so as to not contact a patient's urethra during insertion and removal of the catheter. The catheter includes a double lumen with a one-way flow valve. One lumen provides a passageway to drain urine from a patient's bladder. The second lumen provides a passageway to inflate and deflate the crescent shaped retention balloon.

Abstract: Distal access aspiration guide catheter system and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A distal access aspiration guide catheter having a proximal, medial, and distal possessing high flexibility, high resistance to kinking and a large lumen to wall thickness ratio.

Abstract: Catheter system for inserting and positioning a double-lumen catheter in a blood vessel, including a double-lumen catheter having a distal catheter tip, with a first lumen and a second lumen, a first mandrin which extends through the first lumen and a second mandrin which extends through the second lumen, both mandrins of the catheter being radio-opaque. The distal end of the second mandrin is arranged at a distance (X) in the proximal direction from the distal catheter tip, the distance between the distal catheter tip and the distal end of the second mandrin corresponding in particular to a functional catheter tip length.

Abstract: An apparatus includes a catheter, a housing configured to house at least a portion of the catheter, and an actuator movably coupled to the housing. The housing has a first port configured to receive a proximal end portion of the catheter and a second port configured to couple the housing to an indwelling vascular access device. A portion of the actuator is disposed within the housing and is configured to be movably coupled to a portion of the catheter. The actuator is configured to be moved a first distance to move a distal end portion of the catheter a second distance greater than the first distance from a first position to a second position. The distal end portion of the catheter is disposed within the housing when in the first position and is distal to the indwelling vascular access device when in the second position.

Abstract: A catheter system for pressure wave and inertial impulse generation for intravascular lesion disruption at a treatment site includes a catheter including an elongate shaft and balloon coupled to the elongate shaft. The catheter system includes a light guide disposed along the elongate shaft and at least partially within the balloon, where the light guide is in optical communication with a light source and a balloon fluid. The catheter can include a first focusing element located at a distal portion of the light guide and in optical communication with the light source. The first focusing element can direct light from within the light guide to a first location at a first distance away from the distal portion of the light guide to initiate plasma formation in the balloon fluid away from the distal portion and to cause rapid bubble formation, thereby imparting pressure waves at the treatment site.

Abstract: A catheter system for pressure wave and inertial impulse generation for intravascular lesion disruption includes a balloon coupled to an elongate shaft, and a first and second light guide disposed along the elongate shaft. The first and second light guides each include a diverting feature in optical communication with at least one light window to direct light to exit each light guide toward a side surface portion thereof and toward the balloon. A method includes expanding the balloon from a collapsed configuration to a first expanded configuration, and activating a light source in optical communication with each light guide to provide sub-millisecond pulses of light to the diverting features, thereby inducing plasma formation in a balloon fluid, causing rapid bubble formation, and imparting pressure waves upon the treatment site.

Abstract: Medical article securement systems comprising a viscoelastic polymer and optionally a base layer for securing a medical article to the body of a patient, and particularly, for securing various catheter systems, tubes, or other elongated medical devices to the body of a patient and methods of making and using such.

Abstract: An at least partially implantable medical device can include a body where at least a first portion of the body configured to be implanted through an ostial opening, and at least a second portion of the body configured to at least temporarily retain the body in the implanted position. The second portion can be more distal than the first portion and including a cross-sectional area larger than a cross-sectional area of the first portion. At least one of the first portion or the second portion can be configured to elute a fluid.

Abstract: The invention relates to a puncturing system comprising an outer tubular body which is designed to remain in a body part of a living being, characterized in that the puncturing system has at least one inner tubular body and a puncturing needle, wherein the inner tubular body is guided through a working lumen of the outer tubular body and can be longitudinally displaced with respect to the outer tubular body, and the puncturing needle is guided through a puncture lumen of the inner tubular body and the inner tubular body can be longitudinally displaced with respect to the puncturing needle, wherein, after a body part has been punctured by means of a puncturing section of the puncturing needle, which protrudes out of a patient-side end of the puncturing system, the inner tubular body can be moved out of the patient-side end of the catheter at least partially out of the outer tubular body, and is thereby designed to accommodate the puncturing section of the puncturing needle, which protrudes out of the patient-s

Abstract: The invention relates to a non-invasive ear catheter (1) for introduction into the eustachian tube, comprising a catheter tube (2), an expandable balloon (3) for the occlusion of the eustachian tube, and an injection channel (5) for introducing medication into the middle ear region.

Abstract: A transdermal delivery system for delivery of a triptan into a tissue membrane of a subject. The system includes a transdermal microporation apparatus for heating a skin surface and a triptan drug delivery patch. The drug delivery patch comprises a top layer comprising an adhesive, a middle layer comprising the triptan, and a bottom layer. A method for treating a subject comprises identifying a subject having a migraine, using the transdermal microporation apparatus to open a plurality of micropores in the skin of the subject, and applying the triptan drug delivery patch to the subject's skin over the micropores for a period of time effective to deliver the triptan through the micropores in an amount effective to treat the subject's migraine.

Abstract: Exemplary systems and methods associated with trans-tissue substance delivery using non-thermal plasma to porate skin or tissues using contoured dielectrics/electrodes and grounding techniques. In some embodiments, a substance delivery system may be incorporated into the plasma generating device for automatically controlled skin treatments. In other embodiments, a skin treatment patch may include the electrode and the treatment substance.

Abstract: An object delivery arrangement is disclosed for delivering objects into bone. The arrangement is configured for generating localized mechanical waves into a tissue, for performing localized deposition of the objects near bone, and for exposing the objects and the bone to said mechanical waves to obtain deposition of the objects into the bone.

Abstract: Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.

Abstract: A multi-layer tube for an infusion set for dispensing a fluid includes an outer layer formed of polyurethane and an inner layer formed of high-density polyethylene and/or polypropylene.

Abstract: Antiseptic caps that can be used to disinfect and/or protect medical connectors are disclosed herein. In some embodiments, the antiseptic cap can include a first chamber configured to be removably attached to the medical connector.

Abstract: An example of a system for programming neurostimulation according to a stimulation configuration may include stimulation configuration circuitry, volume definition circuitry, stimulation effect circuitry, and recording circuitry. The stimulation configuration circuitry may be configured to determine the stimulation configuration. The volume definition circuitry may be configured to determine stimulation field model(s) (SFM(s)) each representing a volume of tissue activated by the neurostimulation. The stimulation effect circuitry may be configured to determine a stimulation effect type for each tagging point specified for the SFM(s) and to tag the SFM(s) at each tagging point with the stimulation effect type determined for that tagging point. The stimulation effect type for each tagging point is a type of stimulation resulting from the neurostimulation as measured at that tagging point.

Abstract: A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.

Abstract: A temperature sensor is included within a lead in proximity to distal electrodes. The temperature sensor measures temperature change at the electrode to tissue interface. Actions can be taken when the temperature exceeds a threshold due to heating from current induced by radio frequency energy from an MRI scan. The actions may include sending a signal via telemetry from the implanted device to an external device to produce an alarm to alert an MRI technician or to instruct the MRI scanner to alter the MRI scan. The actions may include activating a switch in the conduction path of an implanted lead to block some of the RF energy and/or to activate a shunt in the conduction path to divert some of the RF energy. The temperature sensor may be of various forms and may be mounted in various locations within the lead.

Abstract: A catheter system and a recapture assembly for the catheter system which serves to expand the system's functionality to support highly-articulated implant recapture. The recapture assembly comprises: a cinch tube with a centering device provided at the distal end of the cinch tube and a tether located within the cinch tube adapted to be telescoped relative to the cinch tube. Also, a method for retrieval of the implant comprising a hitch-like element at its proximal end by the catheter system is disclosed.

Abstract: A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal end face, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position exposed on or spaced from the distal end face. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a substantially straight configuration to a dual hinged curved configuration that maneuvers and positions the electrodes in the vicinity of the bundle of His. The sheath may include a PTFE liner having axially oriented, platelet-like fibril features that enable the sheath to be split along its length from a proximal end to the distal end.

Abstract: Presented herein are techniques for the determination/selection of a set of electrodes for use in an electrically-stimulating auditory/hearing prosthesis. More specifically, an electrically-stimulating hearing prosthesis includes a plurality of electrodes implanted in a recipient. Based, at least in part on a recipient's subjective preferences, one or more of these electrodes may be deactivated. The remaining (i.e., non-deactivated) electrodes form a final electrode set that is subsequently used by the hearing prosthesis for subsequent hearing rehabilitation operations.