Abstract: Endoscope with contamination protection device comprising a rigid or flexible shaft, at a distal end of which optics and a lighting device are disposed, a handle adjoining the shaft, an inner sheath, which is closed at its one distal end and is optically transparent at least on the end face and which is unrolled along the shaft in the manner of a condom, at least one air tube and water tube, which terminate openly at the distal end of the inner sleeve and are connected thereto and are positioned between the shaft and inner sleeve, and a handle attachment, which is plugged onto the handle with an air and a water valve, to which the air and water tubes are connected, an outer sleeve envelops the inner sleeve and, at a proximal end of the inner sleeve, is connected in an air, water and germ-tight manner to the same.

Abstract: An ablation system includes: an endoscope; an ablation treatment tool; an overtube; a first operation member that is provided at a base end portion of the overtube; and a second operation member that is attachable to and detachable from an intermediate position in a longitudinal direction of an insertion portion of the endoscope. The overtube has a balloon that is configured to fix the overtube to the gastro-intestinal tract; the insertion portion and the ablation treatment tool can be integrally moved in the overtube in the longitudinal direction; and the first and second operation members each have a finger holder that holds at least one finger of one hand. The first operation member is distinct from the overtube, and is attachable to and detachable from an outer circumferential surface of the overtube, at an arbitrary position in the longitudinal direction of the overtube.

Abstract: A rigid-scope optical system includes: an image-formation optical system that causes an image in each of wavelength bands to be formed in a predetermined imaging device, the wavelength bands including a fluorescence wavelength band and a visible light wavelength band; and a color-separation-prism optical system having a dichroic film that separates an optical path of light to be imaged into an optical path of the visible light wavelength band and an optical path of the fluorescence wavelength band, in which the image-formation optical system causes the respective images to be formed in a fluorescence imaging device and a visible light imaging device, the fluorescence imaging device and the visible light imaging device being disposed to cause an amount of misalignment to correspond to a difference between an optical path length of fluorescence and an optical path length of visible light.

Abstract: An image processing apparatus includes a special light image acquisition unit that acquires a special light image having information in a specific wavelength band, a generation unit that generates depth information at a predetermined position in a living body using the special light image, and a detection unit that detects a predetermined region using the depth information. The image processing apparatus further includes a normal light image acquisition unit that acquires a normal light image having information in a wavelength band of white light. The specific wavelength band is, for example, infrared light. The generation unit calculates a difference in a depth direction between the special light image and the normal light image to generate depth information at the predetermined position. The detection unit detects a position in which the depth information is a predetermined threshold or more as a bleeding point. The present technology is applicable to an endoscope.

Abstract: A multifunctional visualization instrument is provided that, in certain embodiments, includes a body having a proximal end and a distal end. The multifunctional visualization instrument includes a display screen on the body and a camera stick at the distal end of the body and comprising an arm and a camera. The arm of the camera stick is sized to fit within a channel of a removable laryngoscope blade. The multifunctional visualization instrument includes a port on a surface of the laryngoscope, configured to mate with an introducer and a steering input for steering the introducer, displayed on the display screen simultaneously with an image of the patient captured by the camera.

Abstract: Data is computed in order to visualize the velocity of blood fluid flowing through a blood vessel at a fundus. An image processing method includes a step of performing registration of each frame in a moving image configured by plural frames of an imaged fundus, and a step of computing visualization data enabling visualization of a state of blood fluid flowing through a blood vessel at the fundus based on a pixel value in each of the registered frames.

Abstract: An image is created to visualize the efficacy of treatment to a fundus. An image processing method includes extracting a first frame from a first moving image of an examined eye and extracting a second frame from a second moving image of the examined eye, and comparing the first frame against the second frame.

Abstract: A server in communication with a first device capable of receiving input from a camera attached to the first device, and a second device capable of displaying output, is provided. The server is configured to receive, from the first device, data relating to characteristics of the camera and characteristics of an image obtained by the camera of a screen of the second device; determine a screen pixel length of the screen; and provide instructions to the second device to display on the screen an object at a desired visual angle in response to the data received from the second device and the screen pixel length, while the first device is positioned at an arbitrary distance from the screen.

Abstract: After OCT scans are acquired, error compensation is be applied anew by identifying motion tracking data that was collected simultaneously with (or closest in time to) each acquired OCT scan. The effects of any previously applied motion tracking information is removed from an OCT scan before applying the new motion tracking data, which may provide higher resolution motion tracking.

Abstract: Accordingly, the embodiments of the disclosure provide a method for determining refractive power of an eye of a wearer. The method includes causing to display, by a first electronic device (100), a virtual image of at least one optotype on a display (202) of a second electronic device (200). Further, the method includes varying, by the first electronic device (100), a focus of the optotypes to provide changes in an optical prescription. Further, the method includes conducting, by the first electronic device (100), an eye exam of the wearer based on the varied focus of the optotypes. Further, the method includes determining, by the first electronic device (100), the refractive power of the eye of the wearer.

Abstract: The device of the invention that consists of a gonioscopic lens and gonioscopic lens support for supporting the lens during an ophthalmic procedure. The lens is a cylindrical body with tilted end faces on both end sides. The lens support is a part, which is placed on the patient's eye, while the other side supports the gonioscopic lens. The eye support can be made in different modifications but in any case has a cavity capable of accommodating the eye cornea. The device has two optical lenses. The first lens is a convex lens formed on or attached to the proximal end face of the gonioscopic lens. The second lens is located at the distal end of the gonioscopic lens and may constitute either a concave lens formed on the gonioscopic lens eye support or a concave curvilinear surface of the cavity on the distal end of the gonioscopic lens.

Abstract: An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Abstract: A physiological signal monitoring device includes a base, a biosensor mounted to the base, a transmitter, and a sealing unit. The base is adapted to be mounted to a skin surface of a host. The biosensor includes a mounting seat and a sensing member that is mounted to the mounting seat. The sensing member is adapted to be partially inserted underneath the skin surface of the host for measuring an analyte of the host and to send a corresponding physiological signal. The transmitter is for receiving and transmitting the physiological signal, and has a bottom portion. The transmitter covers the base while the bottom portion faces the base. The sensing member is coupled to the transmitter. The sealing unit is used to seal paths through which a liquid possibly penetrates into an interior of the physiological signal monitoring device so as to avoid damage of the device.

Abstract: A method for assembling a physiological signal monitoring apparatus on a body surface of a living body is provided, wherein the physiological signal monitoring apparatus is used to measure a physiological signal and includes a sensor module and a transmitter. The method comprises steps of: (a) detaching the bottom cover from the housing to expose the sticker from the bottom opening; (b) while holding the housing, causing the adhesive pad to be attached to the body surface; (c) applying a pressing force on the housing to cause the sensor module to be detached from the implantation module and the signal sensing end to be implanted under the body surface; (d) removing the implanting device while leaving the sensor module on the body surface; and (e) placing the transmitter on the base so that the signal output end is electrically connected to the port.

Abstract: A method for performing one or more remote medical examinations of a patient using a workstation operably connectable to a remote diagnostics device, and wherein for at least one remote medical examination of the remote medical examinations the method comprising: receiving navigation enabling data acquired by at least one navigation sensor of the device, the navigation enabling data being indicative of a spatial disposition of the with respect to the patient's body; displaying the received navigation enabling data; receiving an indication of a desired spatial disposition of the device with respect to the patient's body, from which medical data of the patient is to be acquired in accordance with the at least one medical examination, the indication being provided by a trained personnel operating the workstation; and sending the received indication to the device, thus enabling navigation thereof to the desired spatial disposition with respect to the patient's body.

Abstract: Embodiments of remote health monitoring systems and methods are disclosed. In one embodiment, a plurality of sensors is configured for contact-free monitoring of at least one bodily function. A signal processing module communicatively coupled with the plurality of sensors is configured to receive data from the plurality of sensors. A first sensor is configured to generate a first set of data associated with a first bodily function. A second sensor is configured to generate a second set of data associated with a second bodily function. A third sensor is configured to generate a third set of data associated with a third bodily function. The signal processing module is configured to receive and process the first set of data, the second set of data, and the third set of data. The signal processing module is configured to generate at least one diagnosis of a health condition responsive to the processing.

Abstract: Methods for calculating a MetaKG signal are provided. The method including illuminating a region of interest in a sample with a near-infrared (NIR) light source and/or a visible light source. The region of interest includes a sample portion and background portion, each having a different set of optical characteristics. Images of the region of interest are acquired and processed to obtain metadata associated with the acquired images. MetaKG signals are calculated for the region of interest and for the background. The MetaKG signal for the background is used to adjust the MetaKG signal for the region of interest to provide a final adjusted MetaKG signal for the region of interest.

Abstract: An apparatus for estimating bio-information includes a sensor part configured to measure a pulse wave signal and a contact force of an object, while the object is in contact with the sensor part. The apparatus further includes a processor configured to extract a first feature from the measured pulse wave signal and the measured contact force, select one estimation model from a plurality of estimation models, based on a second feature of a user corresponding to the object, and estimate the bio-information, by inputting the extracted first features in the selected estimation model.

Abstract: Provided is an electronic device 100 including a sensor unit 130 configured to acquire a pulse wave of a subject and a controller 143 configured to estimate, using an estimation formula created based on a preprandial pulse wave and a postprandial pulse wave and blood glucose level, a postprandial blood glucose level of the subject based on a difference between the preprandial pulse wave and the postprandial pulse wave of the subject acquired by the sensor unit 130.

Abstract: Provided herein are quantitative optoacoustic tomography systems and methods for dynamic of functional parameters in a subject, for example, to assess conditions of the peripheral vasculature. The system generally has a pulsed laser, a fiberoptic optic bundle light delivery system, and imaging module, an array of ultrawide-band ultrasonic transducers, a circulation system, and electronics/computer system for system control and three-dimensional and two-dimensional optoacoustic image visualization. Also provided is a method for quantitative optoacoustic tomography of an appendage where an appendage of a subject is imaged under conditions of normal, maximum and minimum tolerable temperatures and displaying differential anatomical images of peripheral vasculature in the appendage and functional diagnostic parameters as a function of time and temperature. From this data medical conditions of the appendage may be diagnosed.

Abstract: A method includes a first acquisition step of acquiring a heart rate of a target person who does exercise, a second acquisition step of acquiring an electrocardiographic waveform of the target person who does the exercise, a third acquisition step of acquiring a predetermined feature amount from the acquired electrocardiographic waveform, and an estimation step of estimating a maximum heart rate of the target person based on a relationship between the predetermined feature amount and the acquired heart rate. In the estimation step, the maximum heart rate of the target person is estimated based on a heart rate corresponding to an inflection point in a change of the predetermined feature amount with respect to the acquired heart rate.

Abstract: Methods for training a model for use in monitoring a health parameter in a person are disclosed. In an embodiment, a method involves monitoring a blood pressure of a person using a control blood pressure monitoring system, receiving control data that corresponds to the monitoring using the control blood pressure monitoring system, receiving stepped frequency scanning data that corresponds to radio waves that have reflected from blood in a blood vessel of the person, wherein the stepped frequency scanning data is collected through multiple receive antennas over a range of frequencies, generating training data by combining the control data with the stepped frequency scanning data in a time synchronous manner, and training a model using the training data to produce a trained model, wherein the trained model correlates stepped frequency scanning data to values that are indicative of a blood pressure of a person.

Abstract: Disclosed herein are computer-implemented real-time systems and methods for determining success of a revascularization procedure and/or wound healing of a patient, that can involve measuring blood perfusion characteristics utilizing diffuse speckle contrast analysis (DSCA), and determining blood perfusion and vascular health indices predictive of a likely positive or negative patient outcome, and communicating that outcome to an operator utilizing a display, etc.

Abstract: The disclosed embodiments provide a system that non-invasively analyzes blood flow in a sample of living tissue. During operation, the system obtains light from a temporally coherent source, and splits the obtained light between a reference path and a sample path. Next, the system multiply scatters light from the sample path by passing the light through the sample. The system then recombines light from the reference path and the multiply scattered light from the sample path. Next, the system uses a sensor array to detect an interference pattern resulting from the recombination. Finally, the system analyzes signals from the sensor array to determine a blood flow in the sample.

Abstract: A biological information detection device is robust to color change of external light or illumination light. The biological information detection device includes: an image acquiring section that acquires image information by taking an image of the face of a living body; a blood flow analyzing section that corrects the image information according to the Retinex theory for color constancy, outputs hue information in the corrected image information as blood flow information, and outputs skin area mark information indicating the position of a given skin area in the face; and a local pulse wave detecting section that obtains, from the blood flow information of the skin area corresponding to the skin area mark information, pulse information of the skin area.

Abstract: There is provided an apparatus (12) for controlling a wearable cuff (14) for use in measuring blood pressure, wherein the wearable cuff (14) is inflatable to pressurize a measurement site of a subject (18). The apparatus (12) is configured to initiate the inflation of the wearable cuff (14) at a first inflation speed and change the first inflation speed during inflation of the wearable cuff (14). The first inflation speed is changed at a rate that is limited to a maximum value.

Abstract: In a sphygmomanometer of the present invention, a main body includes a slide receiving part having a circular-arc cross section that opens upward and slidably receiving a cuff unit along a direction perpendicular to the circular-arc cross-section. The cuff unit includes a cylindrical cuff structure having a fluid bag along the inner circumferential surface, and a cover having a circular-arc cross section that opens downward and detachably attached integrally with the cuff structure to cover the upper half of the cuff structure. When the cuff unit is slid along the slide receiving part, upper edges on both sides of the circular-arc cross section of the slide receiving part abut with the lower edges on both sides of the circular-arc cross section of the cover to support the weight of the cuff unit.

Abstract: A method includes receiving a plurality of raw PCG data inputs; applying at least one binary classification technique to each of the raw PCG data inputs to generate a respective plurality of filtered PCG data inputs; applying at least one divide-and-conquer algorithm to detect heartbeat compartments in each of the plurality of the filtered PCG data inputs based, at least on part, on assumptions that noise signals and S1-S2 altemation acoustic signals are non-stationary over a one-minute time interval; classifying each compartment of the heartbeat compartments in each of the plurality of the filtered PCG data input as a maternal compartment or a fetal compartment based at least on a plurality of referenced maternal QRS positions; combining a plurality of maternal compartments to identify at least one actual maternal heartbeat; combining a plurality of fetal compartments to identify at least one actual fetal heartbeat.

Abstract: This disclosure relates to method for estimating heart rate associated with subject in presence of plurality of motion artifacts. The method includes receiving, a photoplethysmography signal and an acceleration signal associated with the subject; learning, by principal component analysis, a projection matrix by projecting input signal into n-dimensional subspaces to obtain a plurality of principal components; selecting, at least one principal component by (a) matching a dominant frequency of the principal components obtained from the PPG signal and a dominant frequency of the principal components obtained from the accelerometer signal, by applying a Fourier transform for a spectrum estimation; and (b) computing, at least one of (i) percentage of energy contributed by the principal component of the PPG signal, (ii) percentage of energy contributed by the principal component of the accelerometer signal; and estimating, the heart rate of the subject based on the at least one selected principal component.

Abstract: An electronic device is disclosed.

Abstract: A biological information detection apparatus includes: a light source which projects a pattern of near-infrared light onto an object including a living body; an imaging system which includes first photodetector cells detecting light in a near-infrared wavelength range and second photodetector cells detecting light in a visible wavelength range, and generates a first image signal representing a first image, which is an image taken in the near-infrared wavelength range, of the object on which the pattern is projected, and a second image signal representing a second image of the object taken in the visible wavelength range; and a calculator which calculates biological information concerning the living body using at least one selected from the group consisting of the first and second image signals.

Abstract: One aspect relates to a body, including at least one first polymer segment having a porosity p1 and an electrical conductivity c1, and at least one further polymer segment being in seamless contact with the at least one first polymer segment and having a porosity p2?p1 and an electrical conductivity c2?c1. One aspect also relates to a process for the preparation of a body, to a body obtainable by such a process, to the use of a body for electrophysical measurements or as a biosensor and to a therapeutic current delivery or current receiving system comprising the body.

Abstract: The present invention relates to an ECG electrode connector (1) and an ECG cable. To eliminate a trunk cable of a conventional ECG cable arrangement, the ECG electrode connector (1) is configured for mechanically and electrically connecting an ECG electrode with a lead wire. It comprises a connection arrangement (10) for mechanically connecting the ECG electrode connector (1) with an ECG electrode (100), a lead wire terminal (14) for connection with a signal line (301) of a lead wire (300), a shield terminal (15) for connection with a shield (302) of the lead wire (300), an electrode contact (17) for contacting an electrical contact (101) of the ECG electrode (100), a voltage clamping element (13) coupled between the lead wire terminal (14) and the shield terminal (15), and a resistor (16) coupled between the lead wire terminal (14) and the electrode contact (17).

Abstract: The system and method provide for electrocardiogram analysis and optimization of patient-customized cardiopulmonary resuscitation and therapy delivery. An external medical device includes a housing and a processor within the housing. The processor can be configured to receive an input signal for a patient receiving chest compressions and to select at least one filter mechanism and to apply the filter mechanism to the signal to at least substantially remove chest compression artifacts from the signal. A real time dynamic analysis of a cardiac rhythm is applied to adjust and integrate CPR prompting of a medical device. Real-time cardiac rhythm quality is facilitated using a rhythm assessment meter.

Abstract: Systems and methods for calibrating an orientation of an implantable device in a patient is described. An exemplary system includes a calibration circuit that can receive acceleration information sensed from an implantable medical device (IMD) implanted in a patient, and receive reference acceleration information sensed from a reference device associated with the patient. The acceleration information and the reference acceleration information are acquired when the patient assumes a first posture or in a first position. The calibration circuit determines a spatial relationship between an orientation of the IMD and a reference orientation of the reference device using the received acceleration information and the received reference acceleration information, and calibrate subsequent acceleration information sensed from the IMD using the determined spatial relationship to correct for the orientation of the IMD.

Abstract: A method includes a first acquisition step of acquiring exercise intensity of exercise done by a target person, a second acquisition step of acquiring an electrocardiographic waveform of the target person who does the exercise, a third acquisition step of acquiring a predetermined feature amount from the acquired electrocardiographic waveform, and an estimation step of estimating an AT of the target person based on a relationship between the predetermined feature amount and the acquired exercise intensity. The estimation step includes a step of estimating the AT of the target person based on exercise intensity corresponding to an inflection point in a change of the predetermined feature amount with respect to the acquired exercise intensity.

Abstract: According to one aspect, the present description relates to a portable device (10) for acquiring electroencephalographic (EEG) signals emitted by a user. The portable device comprises a flexible support (11) intended to fit a localized region of the skull of the user and a set of sensors (13) of electrical signals generated by the neuronal activity of the user, arranged on said support (11) so as to form contacts with the scalp when the device is worn by the user. For each sensor, an electronic circuit for filtering and amplifying electrical signals detected by said sensor is incorporated in the flexible support (11) and forms, with said sensor, an active electrode. The portable device also comprises a housing (12) comprising an electronic system for processing signals from said electronic filtering and amplification circuits, said housing being linked mechanically to the flexible support to form, with said support, a means of attachment to a garment or accessory (101) intended to be worn by the user.

Abstract: Example devices are disclosed herein that include a first elongated band coupled to a first housing to be located on a first side of a head of a subject and a second housing to be located near a second side of the head of the subject, the first elongated band comprising a first set of electrodes. The example device also includes a second elongated band coupled to the first housing and to the second housing, the second elongated band comprising a second set of electrodes. In addition, the device includes a third elongated band coupled to the first housing and to the second housing, the third elongated band comprising a third set of electrodes.

Abstract: Provided herein are systems and methods for automatically determining if a subject is having a stroke. A subject's brain may be monitored with sensors or electrodes to acquire biopotential voltage data. EEG data, power spectrum data and ratios and differences thereof, principal component analysis (PCA) features, and/or other engineered features may be extracted scored with automated machine learning systems. A classifier can identify and/or output if the subject is having a stroke. The subject or a third party can be automatically notified that the subject is having a stroke.

Abstract: An extended wear electrocardiography patch is provided. A flexible backing is formed of an elongated strip of stretchable material. An electrocardiographic electrode is affixed to and conductively exposed on a contact surface of each end of the elongated strip. A flexible circuit is affixed on each end of the elongated strip. A non-conductive receptacle is adhered on one of the ends of the elongated strip on a surface opposite the contact surface and removably receives an electrocardiography monitor operable to obtain electrocardiographic signals. A physiological sensor is provided with the electrocardiography monitor or on the flexible backing. Memory is provided on the flexible backing and is programmed with a sampling rate to instruct the physiological sensor to obtain readings of physiological data. A battery is positioned on one end of the flexible backing to provide power to one or more of the physiological sensors and the electrocardiography monitor.

Abstract: A method for detecting blood-tissue barrier breakdown or disruption is provided. The method includes acquiring first image data of a target region of a subject with a predetermined spatial resolution; administrating exogenous or endogenous tracer into the subject; acquiring second image data of the target region with the predetermined spatial resolution after administration of the tracer; differentiating healthy tissue and pathological tissue with blood-tissue barrier breakdown in the target region based on the first image data and the second image data; and visualizing or analyzing the blood-tissue barrier breakdown of pathological tissue based on the differentiation.

Abstract: An integrated device of a patch and sensor assembly detects extravasation or infiltration. A transmitter is positioned to direct power into a body portion. A sensor is positioned to receive the power transmitted through the body portion. A substrate is attachable to an outer surface of the body portion and supports the transmitter and the sensor. A signal processor is coupled to the transmitter and the sensor for detecting a change in a fluid level in the body portion from extravasation or infiltration based on the power received by the sensor. A power supply is coupled to the transmitter and the sensor. An indicator is responsive to the signal processor to indicate a detected change in a fluid level in the body portion from extravasation or infiltration.

Abstract: A device (10) processes and visualizes EIT data (3) of at least one region of the lungs to determine and visualize ventilation delays in the lungs of a living being. The EIT data (3) are obtained from an electrical impedance tomography apparatus (30). The device makes it possible to visualize regional ventilation delays of the lungs or of regions of the lungs in which the delay exceeds a predefined duration (76) in a joint image (900).

Abstract: A body impedance measurement apparatus and method as well as the transmitter and receiver of a body impedance measurement apparatus are provided. A body impedance measurement apparatus includes transmitter means configured to provide (62) an amplitude modulated signal via a transmitting electrode means (10) to a body to which the transmitting electrode means (10) is applied. The body impedance measurement apparatus also includes receiver means for receiving (64) signals, responsive to the amplitude modulated signal, via a receiving electrode means (12) that is configured to be applied to the body and to be remote from the transmitting electrode means (10) so as to be in wireless communication with the transmitting electrode means (10) via the body. The receiver means is configured to process (68) the received signals to determine a measure of the body impedance.

Abstract: The biotelemetry device (100) comprises a microcontroller (101) for generating an electrical setpoint signal (CS); a radio antenna (103) for transmitting an electromagnetic wave (EMS) by converting an incident electrical signal (IS); a radiofrequency circuit (102), interconnected between the microcontroller (101) and the radio antenna (103). The radio antenna (103) is configured such that, when the biotelemetry device (100) is placed in the biological medium (110), it can be impedance-mismatched relative to the radiofrequency circuit (102) so as to generate a reflected electrical signal (RS) by reflecting a fraction of the incident electrical signal at the same time that the radio antenna is transmitting the electromagnetic wave (EMS).

Abstract: The invention provides for a medical instrument (100, 400, 500, 600, 900, 1000, 1100. 1200, 1400) comprising a magnetic resonance imaging system. The medical instrument comprises: a radio frequency system (116) configured for sending and receiving radio frequency signals to acquire magnetic resonance imaging data (302). The radio frequency system is configured for connecting to a magnetic resonance imaging antenna (114). The medical instrument further comprises a subject support (120) configured for supporting at least a portion of a subject (118) in an imaging zone (108) of the magnetic resonance imaging system. The subject support comprises an antenna connector (124) configured for connecting to the magnetic resonance imaging antenna. The radiofrequency system is configured for connecting to the magnetic resonance imaging antenna via the antenna connector.

Abstract: Analysis of a breath sample is a noninvasive point-of-care tool with ever increasing clinical applicability. Herein we describe a method to analyze the content of low-level, trace volatile organic compounds from alveolar breath captured as a breath sample from a patient. The breath sample is then analyzed using a gas phase analysis methodology, such as gas chromatography-mass spectroscopy (“GCMS”), to generate an analysis result, such as a GCMS spectrum. A computer system is then used to develop a fingerprint pattern from the analysis result. The fingerprint pattern is then used to determine a patient status for the patient. The fingerprint pattern is typically a grouping of 75 to 450 compounds of known concentration which are indicative of a particular neurodegenerative disease.

Abstract: A processing device in one embodiment is configured to generate a first sound cue of a first type, the first sound cue comprising a primary entrainment cue for an entrainment sonification system, to generate one or more additional sound cues of a second type, each of the one or more additional sound cues comprising an auxiliary entrainment cue for the entrainment sonification system, to provide the first sound cue and the one or more additional sound cues to one or more audio devices of the entrainment sonification system for generation of sound for audible presentation to a user, to receive from one or more sensors of the entrainment sonification system one or more feedback signals, and to adjust one or more characteristics of at least one of the first sound cue and the one or more additional sound cues based at least in part on the one or more received feedback signals.

Abstract: An apparatus and a method are described in which a signal is received from a gyroscope sensor mounted on a subject. The gyroscope sensor is configured to measure rotational movement of the subject's heart, the signal being indicative of a left ventricular twist of the subject's heart. A change in the left ventricular twist of the subject's heart caused by occlusion of blood flow by an arterial occlusion device configured to selectively occlude blood flow of the subject is determined.

Abstract: A method for disabling a step-counting function of a wearable fitness tracker includes detecting a vehicle start-up event of a vehicle with one or more vehicle sensors, and sending an in-vehicle confirmation signal from one or more vehicle communication modules to one or more wearable fitness trackers positioned within the vehicle in response to detecting the vehicle start-up event. The in-vehicle confirmation signal is configured to be received by the one or more wearable fitness trackers and cause the one or more wearable fitness trackers to automatically disable the step-counting function of the one or more wearable fitness trackers.