Abstract: Electrical field imaging is performed using optionally any of a range of medical implements having a designated medical use (e.g., having a working portion for manipulating tissue); and furthermore supplied with at least one electrode that is used to transmit and/or receive an electrical field which interacts with the dielectric properties of tissue. In some embodiments, the at least one electrode is supplied as an add-on assembly, optionally as part of a kit including the medical implement.

Abstract: An articulable wrist for an end effector includes a first linkage, a second linkage rotatably coupled to the first linkage at a first articulation joint, and a flexible member extending at least partially through a central channel cooperatively defined by the first and second linkages. A first pivot guide is rotatably coupled to the second linkage at the first articulation joint and rotatable about a first pivot axis extending through the first articulation joint, the first pivot guide defining a central aperture alignable with the central channel and sized to accommodate the flexible member therethrough. The first pivot guide supports an outer diameter of the flexible member at the first articulation joint and prevents the flexible member from flexing beyond the first pivot axis during articulation.

Abstract: An articulable wrist for an end effector includes a first linkage rotatably coupled to a second linkage at a first articulation joint, a flexible member extending at least partially through a central channel cooperatively defined by the first and second linkages, and a first pair of roller supports arranged at the first articulation joint and laterally offset from each other, each roller support extending parallel to a first pivot axis extending through the first articulation joint. A drive cable extends through a first axially-extending conduit defined in the flexible member and through a gap defined between the first pair of roller supports. The drive cable is supported at the first articulation joint by the first pair of roller supports during articulation and the first pair of roller supports prevents a centerline of the drive cable from moving past the first pivot axis during actuation of the end effector.

Abstract: An end effector for a surgical tool includes a first jaw that defines an aperture, a second jaw rotatably coupled to the first jaw, and a spacer pin received within the aperture and protruding from an upper surface of the first jaw. The spacer pin is adjustable within the aperture to define a jaw gap between the first and second jaws when the second jaw is moved to a closed position and engages the spacer pin, and the spacer pin is secured within the aperture to set the jaw gap.

Abstract: Systems and methods for setting up and evaluating positioning of robotic arms of a surgical device using procedure data including previous surgeries is described herein. Robotic surgical systems described herein include color-configurable lights connected to each robotic arm of the system. A first color and a second color are selected and emitted from each light and the color displayed by the light of each robotic arm is also displayed at the surgical console of the system. Further, systems and methods for providing a position quality score for each robotic arm and surgical port as well as the overall system are described. The position quality score is determined based on comparing the position of each robotic arm to a database of positions for the robotic arms during a procedure and lowering the score for deviations from the database of positions.

Abstract: A system for performing a medical procedure on a patient includes an articulating probe assembly and at least one tool. The articulating probe assembly comprises an inner probe comprising multiple articulating inner links, an outer probe surrounding the inner probe and comprising multiple articulating outer links, and at least two working channels that exit a distal portion of the probe assembly. The at least one tool is configured to translate through one of the at least two working channels. The at least one tool is robotically controlled.

Abstract: A surgical robotic system includes a robotic arm, an elongated slide coupled to the robotic arm, and an instrument drive unit coupled to a track defined by the slide. The instrument drive unit is configured to move along the track and includes a motor configured to interface with an electromechanical instrument to actuate functions of the electromechanical instrument. The slide is configured to rotate relative to the robotic arm about a longitudinal axis defined by the instrument drive unit.

Abstract: Systems, devices and methods are provided in which an instrument can translate along an insertion axis. Rather than relying primarily on a robotic arm for instrument insertion, the instruments described herein have novel instrument based insertion architectures that allow portions of the instruments themselves to translate along an insertion axis. For example, an instrument can comprise a shaft, an end effector on a distal end of the shaft, and a handle coupled to the shaft. The architecture of the instrument allows the shaft to translate relative to the handle along an axis of insertion. The translation of the shaft does not interfere with other functions of the instrument, such as end effector actuation.

Abstract: The present invention provides a medical robot which is hygienic and capable of precisely transferring a catheter, a driving device mounted on the medical robot, and a roller module mounted on the driving device. The roller module includes: a driving unit; and a roller unit rotated about the vertical axis by the driving unit, wherein the roller unit includes at least one roller and at least one shaft independently coupled to the at least one roller of the roller unit and rotated by the driving unit, wherein at least one groove is formed on the at least one roller of the roller unit and at least a part of the at least one shaft of the roller unit is disposed on the at least one groove.

Abstract: A system and method of controlling an end effector includes a drive unit having a first actuator and a second actuator, a moveable platform drivably coupled to the first actuator, first and second engagement members drivably coupled to the second actuator; and a control unit. The control unit is configured to actuate the first actuator to drive the platform, detect engagement of the first engagement member with a third engagement member of an instrument, detect engagement of the second engagement member with a fourth engagement member of the instrument, and actuate the second actuator to drive the first and second engagement members. Movement of the third and engagement member causes movement of a degree of freedom of an end effector of the instrument in a first direction. Movement of the fourth engagement member causes movement of the degree of freedom in a second direction opposite the first direction.

Abstract: Systems and methods for controlling an elongate device include a console. The console includes a first recess and a removable first input control for controlling motion of the medical device. The console also may include one or more first sensors located about the first recess that detect motion of the first input control and detect operator contact with the first input control. The console also may include an integrated display screen arranged to display status information for the medical device.

Abstract: Many variations of systems, methods and apparatus for counting medical procedure objects, reconciling same, estimating patient blood loss during and/or after a procedure, and/or communicating between medical equipment used in a medical procedure setting are disclosed and/or illustrated herein. More particularly, many systems, methods and apparatus for counting and/or reconciling medical sponges with passive or active tracking devices, properly detecting/estimating blood loss during and/or after a medical procedure to assist with transfusion decision-making and identifying or at least alerting as to post-procedure patient risks, and/or for communicating between devices used during procedures to provide a smart/connected medical procedure environment are disclosed and/or illustrated herein.

Abstract: A robotic surgical tool includes a tool driver, a drive housing mountable to the tool driver and including one or more component parts made of or including a magnetically responsive material, a first inductor coil included on the tool driver and configured to generate a magnetic field, and a second inductor coil included on the drive housing and configured to measure an intensity of the magnetic field and a field distortion caused by the one or more component parts. A change in the field distortion provides an indication of movement of the one or more component parts.

Abstract: The present invention relates to a template for a positioning, fixation, mobilization or immobilization device, wherein the template comprises a sheet of a thermoplastic material, wherein the thermoplastic material comprises between 3.0 and 95.0 wt. % of a poly-?-caprolactone polymer, preferably a poly-?-caprolactone homopolymer, and at least 5.0 wt. % of at least one second polymer material with a melting temperature of between 40 and 85° C., wherein the at least one second polymer material is selected from the group of one or more of a polyalkenamer or a thermoplastic linear polyurethane which contains as a polyol a poly ?-caprolactone or a polyester polyol, wherein the poly-?-caprolactone polymer and the second thermoplastic material are cross-linked.

Abstract: A surgical headlight system has a headlamp. The surgical headlight system can further include a headwear structure, configured to be worn on a surgeon's head during surgery, supporting the headlamp. The surgical headlight system can further include a video camera configured to record surgery. The headlamp, the headwear structure and the video camera all have an exterior surface. An antimicrobial coating is applied to the exterior surface of the headlamp, the exterior surface of the video camera, and/or the exterior surface of the headwear structure. The antimicrobial coating includes a silane quaternary ammonium ion or salt thereof. The antimicrobial coating imparts antimicrobial properties onto the exterior surface to which it is applied, such as the exterior surface of the headlamp.

Abstract: A disposable medical clamp light is described. The disposable medical clamp light includes a light source, a housing, and at least one attachment. The at least one attachment is configured to couple the disposable clamp light to a medical device. The at least one attachment may include an attachment clip having a first arm and a second arm extending from the housing, wherein the first arm and the second arm are configured to surround a portion of the medical device to attach the disposable clamp light to the medical device. The disposable medical clamp light may be coupled a medical device using the at least one attachment to form a lighted clamp system configured for foreign body removal from a patient. The disposable clamp light can further include a power source and a switch electrically communicating with the light source.

Abstract: A smart marking system for a surgical video and a method thereof are disclosed. The image recognition is performed for each surgical video to generate object information corresponding to each surgical video. The object information is used as feature data of the surgical video corresponding thereto. After a video to be analyzed is loaded, eigenvalue analysis and statistics are performed according to the video to be analyzed and all the feature data to calculate a similarity rate between the video to be analyzed and each surgical video. A surgical name corresponding to the surgical video with the highest similarity rate is selected to mark as a surgical name corresponding to the video to be analyzed. The video to be analyzed and the surgical name corresponding thereto are stored in a database as the surgical video. Thus, the efficiency of marking the surgical videos is improved.

Abstract: An augmented reality surgical guidance system includes an augmented reality device and a plurality of mobile surgical tracking devices, including at least a first mobile surgical tracking device and a second mobile surgical tracking device, wherein at least one of the first or second mobile surgical tracking devices is connected to an object. The first mobile surgical tracking device includes a marker, a sensor and a control unit. The sensor of the first mobile surgical tracking device is configured to track the position of the second mobile surgical tracking device or the augmented reality device. The sensor is connected to the control unit to provide positional information data of the second mobile surgical tracking device to the control unit. The control unit includes a transmission unit configured to transmit the positional information data to the augmented reality device and the augmented reality device includes an imaging device and a display.

Abstract: A robotic operating table according to an embodiment may include: a tabletop on which a patient can be placed; an articulated robot arm that supports the tabletop to be movable; and a communication part to communicate with the inspection information management device. The communication part is configured to receive, from the inspection information management device, attention position information indicating an attention position in the patient specified based on an image of the patient captured by the medical imaging device. The articulated robot arm is configured, based on the attention position information received from the inspection information management device, to move the tabletop to a surgery-performing tabletop position which is the position of the tabletop at the time when surgery is executed on the patient.

Abstract: The medical instrument support device comprises a harness with a plate (1) which can be fixed by means of straps, a fastening element (3) and a second fastening element (4) which can be attached to and is detachable from the first fastening element (3), an articulated joint (5) of tubular and elongated shape, fixed integrally and removable at its end to the first fixing element (3) and supporting at its second end a housing (6) angularly adjustable in space and fixable in any position angular with a manual clamp (7), where the housing (6) is configured to support the medical device.

Abstract: A tool measures the cleanliness of the interior of an endoscope channel, wherein the tool is for efficiently, rapidly, and reliably examining whether or not an endoscope is clean after being cleaned and sterilized. The tool for measuring the cleanliness of the interior of an endoscope channel is characterized in that a wiping cloth containing ultrafine fibers is attached to the tip of a filament having a thickness enabling the filament to be inserted into the endoscope channel.

Abstract: The present invention is an improved dental drill and system of assisting patients with anxiety due to dental visits. The Audio Drill system collects data such as music and time for the purposes of receiving audio data packets from a mobile device. Mobile devices such as smart phones, tablets, Internet computers, and other hand-held mobile devices are ideal for submitting music to the proposed invention. The affiliations are determined based upon the audio date and other critical markers. The system may even be enhanced by use of features tailored by the user.

Abstract: A system for manufacturing a three-dimensional article includes a controller configured to: receive an input file defining a geometry of the three-dimensional article; receive information specifying an interface surface of the article over which the article will fit against a three-dimensional body; slice the geometry; identify intersecting slices that intersect the interface surface; and for the intersecting slices, alter a halftone range along the interface surface. Along the interface surface, the article slidingly engages the three-dimensional body. The sliding engagement can be sufficient to provide a fluid seal along the interface surface.

Abstract: A method for preserving the alveolar ridge using partial extraction therapy. The method comprises de-coronating the tooth to leave a tooth root, de-coring a coronal portion of the tooth root to leave a tooth ring, severing an apical root portion of the tooth root from the tooth ring and removing the apical root portion. The tooth ring provides a ring of natural material that reinforces the coronal part of the tooth socket in the gum and reduces or obviates alveolar resorption.

Abstract: The present disclosure concerns a subperiosteal dental implant for receiving at least one replacement tooth of a patient, the subperiosteal dental implant comprising an implant frame superposable to at least a section of a jaw hone of the patient, the implant frame having a bone-facing surface at least partially contacting the jaw hone of the patient when the implant frame is superposed thereto, and an opposed gum-facing surface, the implant frame having at least a section along which a cross-section profile includes a base defining at least partially the bone-facing surface and at least partially the gum-facing surface, a ridge protruding from the base and defining at least partially the gum-facing surface, and a first shoulder and a second shoulder that are both defined on the gum-facing surface of the base, each one being located on a respective side of the ridge.

Abstract: The present invention relates to a dental device (1) for removing a dental implant (2) which is at least partially or fully osseointegrated with a patient's jaw (3), comprising: a head portion (6) for rotatingly holding a dental tool (7) for unscrewing the dental implant (2); and a driving means for applying a torque to the dental tool (7) for unscrewing the dental implant (2); characterized in that the driving means is further adapted to apply pulsed torques (?; ?1, ?2, ?3) to the dental tool (7) to unscrew the dental implant (2).

Abstract: A dental flosser is disclosed. The dental flosser comprises a U-shaped portion having a first arm and a second arm spaced apart from each other, a handle portion which extends from the U-shaped portion, a floss strand having a length and a first end and a second end, and a floss strand attachment member. The first end of the floss strand is fastened to the first arm of the U-shaped portion, and the second end of the floss strand is fastened to the floss strand attachment member, and a middle portion of the floss strand is slideably mounted to the second arm of the U-shaped portion. A user can maneuver the floss strand attachment member to increase or decrease or maintain tension of the floss strand.

Abstract: The present invention discloses a teeth whitening product containing a piezoelectric material. The present invention uses a piezoelectric material with piezoelectric effect as a whitening ingredient of the teeth whitening product. The teeth whitening product is applied to teeth and exerts pressure on the tooth surface to activate piezoelectric properties of the piezoelectric material. Thus, abundant reactive species are produced to degrade teeth stains, achieving teeth whitening. The teeth whitening product of the invention is safe and nontoxic; a teeth whitening method is easy to operate, does not cause damage to oral soft tissues, enamel layers on the tooth surface, and the tooth structure, and obtains a long-lasting teeth whitening effect.

Abstract: A silicone prosthesis delivery apparatus and associated methods are disclosed for facilitating the transport and subsequent insertion of a silicone prosthesis into a surgically developed pocket of a patient. In at least one embodiment, a flexible, substantially funnel-shaped delivery sleeve is configured for receiving and subsequently expelling the prosthesis therefrom. The delivery sleeve provides a substantially conical-shaped entry portion and a substantially conical-shaped exit portion, the entry portion and exit portion opposingly positioned and joined with one another so as to form a relatively larger diameter middle section. A tapered free end of the entry portion provides an entry opening configured for allowing the prosthesis to selectively pass therethrough when the prosthesis is inserted into the delivery sleeve.

Abstract: Methods and devices are provided for protecting the cerebrovascular circulation from embolic debris released during an index procedure. An embolic protection filter is delivered in a reduced profile configuration via an access catheter, and positioned in the aorta spanning the ostia to the three great vessels leading to the cerebral circulation. An index procedure catheter is thereafter advanced through the same access catheter to conduct the index procedure. The index procedure may be a transcatheter aortic valve replacement. A pore distribution in the filter blocks passage of debris greater than a predetermined threshold, minimizes total cumulative volume of debris passing through the filter and minimizes blood pressure drop across the filter.

Abstract: An endovascular device including a filter, at least one sensor, and a controller is disclosed. The filter has a proximal end and a distal end, and the filter is inserted into a body lumen and collects embolic materials as the embolic materials travel through the body lumen from the proximal end toward the distal end. The at least one sensor is located near the filter and perform physiological measurements within the body lumen. The controller coupled to the at least one sensor determines a fill level the filter based on the physiological measurements received from the at least one sensor.

Abstract: A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.

Abstract: Disclosed are implantable tubular devices having a fenestration in a wall of the tubular device and a conductive coil positioned around the fenestration, such that the coil is operable to generate a magnetic field when electrical current flows through the coil. The magnetic field can be used to draw a ferrous or magnetically tipped guidewire or other device to and through the fenestration. In the example of a fenestrated endovascular graft, the coil can be used to draw a guidewire out through a fenestration into a branch blood vessel, such that the guidewire can be used to deliver a branch of the graft through the fenestration into the branch vessel. A power source can be contained in a nosecone.

Abstract: The invention discloses a stent graft used for interventional treatment of abdominal aortic disease, comprising a tube body composed of a tubular covering and a plurality of annular stents, and the tube body comprises a first tube body and a second tube body that arranged in sequence from the proximal end to the distal end, wherein the diameter of the first tube body is greater than diameter of the second tube body; the first tube body and the second tube body are connected by a transition section as a whole; the diameter at central part of the transition section is smaller than the diameter of the proximal end of the transition section and the diameter of the distal end of the transition section; a plurality of fenestrations are disposed on the first tube body and the transition section.

Abstract: An in-situ implanted bionic artificial anal sphincter system with an independent swing arm structure comprises: an energy transmission control unit and a sphincter prosthesis unit. The energy transmission control unit comprises a master control module and a percutaneous wireless energy transmission module while the sphincter prosthesis unit comprises a wireless energy receiving module, a micro power supply, a sensor, an execution unit and a slave control module. The invention has a simpler and compact structure which reduces the risk of transplanting; the middle ring with independent rotating shaft has simple structure and reduces the difficulty of installation; the hall switch is arranged in the upper ring bin to facilitate wiring; the external gear meshing transmission torque is simple and reliable.

Abstract: An example implant delivery system is disclosed. The example implant delivery system includes a delivery shaft including a proximal portion, a distal portion and a lumen extending therebetween. The delivery system also includes a frame detachably coupled to the distal portion of the delivery shaft and a tack member coupled to the frame.

Abstract: Provided are intraoperative devices, the devices comprising a substrate having a plurality of discontinuous cuts formed therein, the plurality of discontinuous cuts being formed such that when the substrate is subjected to deformation, the substrate is capable of deformation beyond an initial state so as to achieve a first shaped three-dimensional state. Through design of the cut patterns in 2D, one can locally control the stretchability and elasticity within the substrate. The substrate can then be deformed into a 3D structure that can provide shape and support to reconstructed tissue in the desired regions while also minimizing operative time and cost. Also provided are related methods of using the disclosed devices; the devices can be used in autologous tissue donation procedures as well as prosthetic procedures.

Abstract: A system for vision correction and enhancement which may include lenses and surfaces coated with materials with tunable reflectivity is provided. Methods of using the system for correcting and enhancing vision is also provided.

Abstract: Systems, methods, and apparatuses for inserting an intraocular lens (IOL) into an eye, are provided. The apparatus comprises an IOL cartridge comprising a nozzle, a compartment, a plunger, and a plunger case. The nozzle is in fluid communication with the compartment, and the plunger case is in fluid communication with the compartment. The plunger is disposed within the plunger case. The plunger case includes flexible members extending from an outer surface of the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for inserting an intraocular lens (IOL) into an eye, are provided. An apparatus comprises an IOL cartridge comprising a nozzle, a compartment, and a plunger case. The nozzle is in fluid communication with the compartment, and the plunger case is in fluid communication with the compartment. The plunger is disposed within the plunger case. The plunger case is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon retraction of a cap, are provided. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge also includes a retractable cap that covers the nozzle and the compartment. The retractable cap is configured to expose the nozzle and fold the IOL upon retraction of the retractable cap. The IOL cartridge may also include a plunger case that is in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon removal of a cap, are provided. The IOL cartridge comprises a nozzle and a housing comprising a slide. A compartment configured to receive an IOL is disposed within the housing. An interior portion of the slide is exposed to the compartment. The nozzle is in fluid communication with the compartment. The cap covers the nozzle and the slide. The cap is configured to expose the nozzle and advance the slide to fold the IOL upon removal of the cap.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises the IOL cartridge. The IOL cartridge comprises a nozzle and a compartment comprising an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial disposed adjacent to the compartment, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL upon rotation of the dial. The IOL cartridge further comprises a plunger case in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises a packaging comprising a passage. The IOL cartridge is removably disposed within the passage. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial configured to rotate upon withdrawal of the IOL cartridge from the passage, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL and release the IOL cartridge from the packaging upon rotation of the dial.

Abstract: Methods and devices are provided for protecting the cerebrovascular circulation from embolic debris released during an index procedure. An embolic protection filter is delivered in a reduced profile configuration via an access catheter, and positioned in the aorta spanning the ostia to the three great vessels leading to the cerebral circulation. An index procedure catheter is thereafter advanced through the same access catheter to conduct the index procedure. The index procedure may be a transcatheter aortic valve replacement.

Abstract: A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.

Abstract: A method of delivering an anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of a super elastic wire-like member defining a continuous, closed shape. The docking station can have an upper or atrial ring with at least two ring portions or half rings that are spaced apart across gaps. Descending bends from the ends of the two ring portions lead to a pair of anchors. The anchors can include oppositely-directed rounded V-shaped arms that extend generally parallel to the upper ring. The anchors can be delivered to be located in the subvalvular space or the region/vicinity of the native leaflets and pinch the leaflets and the annulus against the upper ring which is located on the other side of the annulus.

Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

Abstract: The present application relates to a cardiac valve prosthesis and a stent thereof. The stent comprises an inflow channel, an outflow channel, and a transitional area between the inflow channel and the outflow channel along an axial direction; the outflow channel comprises a cyclic structure and at least two convex structures extending along the axial direction; the at least two convex structures are respectively connected to the end of the cyclic structure distant from the transitional area; a restricted vacant area is formed between adjacent convex structures. The cardiac valve prosthesis and the stent thereof are not only suitable for multiple types of valve replacement, risks of injuries and operation costs are reduced for patients, and the influence of the stent to cardiac functions is minimized.

Abstract: In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.