Abstract: An optical sensor for an instrument to form a closed-loop curing instrument that is configured to manage the quantity of delivered energy to a curable material, including a composite restoration for a tooth. The closed-loop curing instrument is configured to analyze a signal indicative of the light reflecting from the curable material, and to adjust light output based on the analysis.

Abstract: An oral care implement for dispensing an oral care agent includes a housing, reservoir therein containing an oral care fluid, and an electrical circuit comprising first and second electrodes connected to an onboard power source. Each electrode is in contact with the oral care fluid in the housing. An actuator, operably coupled to the power source, is configured to both selectively energize the circuit and activate dispensing of the oral care fluid. An electrical charge is applied to the oral care fluid by activating the actuator when dispensing the oral care fluid. When the fluid comprises a peroxide based tooth whitening agent, the dispensed fluid pH is increased by the electrical charge which improves the efficacy of the whitener. In one embodiment, the implement is a modular system including a powered base unit and one or more interchangeable cartridges each having a reservoir containing an oral care fluid.

Abstract: Embodiments of elongate pelvic implants and methods for treating pelvic conditions, such as incontinence, are provided. The implants can include a tissue support portion, one or more extension portions and one or more anchors. The implant is constructed as a unitary sling implant. The implant can be constructed or formed in a generally elongate shape to provide a lattice support structure of repeated cells.

Abstract: A medical implant which is vacuum-packed within an air tight cover material and a medical device for making the same is provided. Also described herein is a method for making a medical implant covered by an air tight cover material, comprising the steps of a) providing the medical implant, b) providing sterile cover material in the form of at least one or at least two pieces, c) placing the medical implant within a space surrounded by the at least one or at least two pieces of the cover material, d) creating an underpressure within the space surrounded by the at least one or at least two pieces of the cover material by evacuating air from this space, and e) air tight sealing of the cover material.

Abstract: Devices, systems, and methods for delivering prosthesis implants into surgically-created implant pockets in a subject and for preventing capsular contracture resulting from surgical insertion of prosthesis implants. The device may include a delivery member operable to wrap around the implant thereby forming a conforming cavity around the implant that conforms to the shape of the implant. The delivery member is also operable to propel the implant from the conforming cavity into the implant pocket in the subject upon the application of mechanical force to the delivery member. The device also includes a shielding member coupled with the delivery member. The shielding member is operable to shield the implant from at least a portion of the dissection tunnel connecting the incision to the implant pocket during delivery of the implant to the implant pocket.

Abstract: A stent graft including a stent having a wall having at least one opening, an outer surface, and an inner surface and a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

Abstract: An implantable tendon protection system includes a body adapted to be implanted within a bursa overlying a tendon of a patient to protect the tendon. The body may be fixed to the tendon with adhesive, sutures, staples, and/or anchors. A surgical kit is provided with such a tendon protection system and an insertion cannula. Methods of protecting a tendon of a patient are also disclosed.

Abstract: Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Abstract: Some embodiments disclosed herein relate to devices and methods for controlling placement of intraocular implants within a patient's eye including but not limited to placement within or near the collector ducts of Schlemm's canal located behind the trabecular meshwork. In some embodiments, a handheld peristaltic rotor device having a compression element can be positioned on a corneal surface of the eye and rotated to create a peristaltic movement of blood in one or more episcleral veins to generate blood reflux within Schlemm's canal such that one or more collector ducts, or channels, of Schlemm's canal can be located. In some embodiments, an implant can be implanted near the identified location of the one or more collector ducts, or channels.

Abstract: An IOL injector having a lever-driven plunger mechanism is described.

Abstract: Intraocular lens injectors described herein may include a symmetrical arranged storage compartment, nozzle passage, and plunger tip in order to symmetrically fold and provide symmetrical loading to an intraocular lens during advancement and delivery so as to avoid rotation of the intraocular lens about longitudinal, vertical, and/or lateral axes during advancement and/or delivery of the intraocular lens.

Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).

Abstract: A delivery apparatus for implanting a prosthetic implant in a native lumen of the body includes a handle portion, and a first shaft extending from and movable relative to the handle portion. The first shaft has a proximal end portion coupled to the handle portion and a distal end portion. The delivery apparatus further includes a second shaft extending from the handle portion and coaxially disposed within the first shaft. The second shaft has a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic implant in a radially compressed state. The handle portion of the delivery apparatus also includes a steering assembly configured to move the first shaft longitudinally relative to the second shaft while concurrently flexing the second shaft.

Abstract: A medical device apparatus may include a medical implant including a braided anchor member configured to actuate between a delivery configuration and a deployed configuration operatively connected to a delivery system. The delivery system may include a handle, an outer sheath extending distally from the handle, and an inner catheter disposed within the outer sheath. A sheathing aid may connect the delivery system to the medical implant, the sheathing aid being configured to guide the medical implant into the outer sheath upon relative closing movement therebetween. The sheathing aid may include a plurality of arms extending from the inner catheter to a proximal end of the braided anchor member. At least one arm of the plurality of arms may comprise a core member having a width and a flexible member positioned about the core member.

Abstract: A method of delivering a prosthetic heart valve to a native aortic heart valve region of a patient can include introducing a prosthetic heart valve on a transvascular delivery apparatus into an artery of the patient, advancing the delivery apparatus through an aorta of the patient to the native aortic heart valve region, and releasing the prosthetic heart valve from the delivery apparatus. The delivery apparatus can have a shaft with a valve connection portion that is releasably coupled to posts of the prosthetic heart valve. The delivery apparatus can have a delivery sheath positioned around the prosthetic heart valve and the valve connection portion. The releasing the prosthetic valve can include moving the delivery sheath proximally relative to the shaft and the prosthetic heart valve such that the delivery sheath uncovers the prosthetic heart valve and the prosthetic heart valve can self-expand.

Abstract: A handle assembly for a transvascular prosthetic heart valve delivery apparatus including a handle housing, a main shaft extending distally from the handle housing, the main shaft configured to be coupled to a distal valve sheath that is configured to retain a prosthetic heart valve in a radially compressed state within the valve sheath, a screw shaft, a control knob that is rotatable relative to the handle housing and the screw shaft, a screw engagement latch that is adjustable between an engaged position and a disengaged position. In the engaged position, the latch can couple the control knob to the screw shaft such that rotation of the control knob relative to the handle housing causes the main shaft to move axially relative to the handle housing. In the disengaged position, the latch can decouple the control knob from the screw shaft such that the main shaft can move axially relative to the handle housing without rotation of the control knob.

Abstract: The present disclosure relates to repair devices and methods for repair of regurgitant tricuspid valves. A repair method includes positioning a repair device at a tricuspid valve in a collapsed configuration. The repair device includes a proximal grasping assembly movable between a first position and a second position and a distal grasping assembly movable between a third position and a fourth position. An actuator rod operatively connected to each of the proximal grasping assembly and the distal grasping assembly so that distal movement of the actuator rod simultaneously moves the proximal grasping assembly proximally and the distal grasping assembly distally.

Abstract: An annuloplasty implant is provided for treating a native atrioventricular valve of a patient, the annuloplasty implant including a plurality of tissue anchors, which are configured to anchor the annuloplasty implant around at least a portion of a valve annulus of the native atrioventricular valve. The annuloplasty further includes a contracting assembly, which includes an elongate contracting member; and a contracting mechanism, which is coupled to the elongate contracting member, and which is configured, upon actuation thereof, to apply a longitudinal contracting force to the elongate contracting member that longitudinally contracts at least a portion of the annuloplasty implant, thereby circumferentially tightening the valve annulus. The annuloplasty further includes a force-distributing element, which includes a longitudinally-non-compressible tightly-coiled element, and which is configured to distribute the longitudinal contracting force over at least two of the tissue anchors.

Abstract: The present invention relates to a device for cardiac valve repair, the device comprising: at least one upstream anchoring means adapted to anchor to at least one tissue site, the tissue site located upstream with respect to a heart valve of a patient; and a coaptation structure arranged to extend from the upstream anchoring means, the coaptation structure comprising a free end, wherein the coaptation structure is operable to extend across the heart valve and locate the free end downstream from the heart valve and the coaptation structure operable to coapt with at least one heart valve leaflet of the patient's heart to prevent and/or minimize a backflow of blood. The present invention is suitable for the treatment of heart valves using minimally invasive approaches. Additionally, the present invention is directed to a method of implanting a device for cardiac valve repair in a patient's heart.

Abstract: A prosthetic system for heart valve replacement comprises an annular support structure within which a valved prosthetic body can be expanded until it meets opposition. The annular support is provided in ring segments having terminal connectors for forming, in the condition of use of the prosthetic system, a stable and durable annular structural continuity capable of withstanding the opposition exerted by the valved prosthetic body. The prosthetic system is deployed using guide wires within a cardiac chamber guided through an introducer catheter having through lumens, within which at least two first guide catheters are positioned. These guide catheters have respective deflected or deflectable distal ends adapted to emerge from the distal end of the introducer catheter to convey and direct the distal ends of respective guide wires, placed within the guide catheters, towards a capture member of a capture system which is provided within the introducer catheter.

Abstract: Anatomically shaped augments that are configured for implantation in a bone and which have one or more reliefs. A distal end of an outer portion of the augment can have a shape that is configured to generally conform to the shape of a metaphyseal-diaphyseal junction of an intramedullary canal of a bone. A proximal end of the outer portion can have a shape that is configured to generally conform to a shape of the metaphyseal region of the intramedullary canal. The reliefs can be configured to reduce a size of the augment and enhance the degree of freedom in the implant positioning and/or sizing of the augment. Further, such reliefs may contour the augment so as to prevent cortical bone contact and/or prevent contact with the implant device that may be associated with misalignment between an intramedullary canal and metaphyseal or diaphyseal regions of the bone.

Abstract: Methods for preparing bone void filler substrates with carbonate surface coatings to promote bone growth.

Abstract: A system and method for further improving upon an ability of a surgeon to reduce or eliminate impaction forces when installing or assembling a prosthesis. An implant includes a surface treatment for aiding operations with the implant. For example, some surface treatments provide an asymmetry in installation versus removal to bias the associated implant deeper into an installation site.

Abstract: A resorbable scaffold for partial meniscus regeneration. The resorbable scaffold includes a polymer filament network and a matrix in the polymer filament network. The polymer filament network includes alternating layers of circumferentially-oriented filaments and radially-oriented filaments, and has a three-dimensional shape and geometry which is substantially the same as a three-dimensional shape and geometry of the resorbable scaffold.

Abstract: An orthopaedic prosthesis includes a femoral component configured to be attached to a distal end of a patient's femur. A tibial tray is configured to be attached to a proximal end of a patient's tibia. A tibial insert is configured to rotate relative to the tibial tray. A modular insert is received in a cavity defined in the tibial insert. The femoral component is rotatably coupled to the body of the modular insert.

Abstract: A total artificial spinous process (spino)-laminar prosthesis (TASP-LP) including a body having a portion forming a spinous process extending away from the body, a first lamina portion extending from a first side of the body, and a second lamina portion extending from a second side of the body, wherein the first lamina portion and the second lamina portion are disposed on opposite sides of the spinous process.

Abstract: The invention relates to medical implants, including spinal implants and bone grafts, for fixation and integration with hard tissue. The bone medical implants include at least one rotational fixation mechanism that further includes or is attached to one or more sharp protrusions configured to penetrate and become lodged into hard tissue to provide support and positional stability. Such support is useful to ensure that the spinal bone graft may be used without additional stabilizing or anchoring structures, such as supporting plates or screws.

Abstract: An example expandable interbody device can include a structural body having an upper endplate and a lower endplate. The device can include at least one wedge block and at least one linkage block arranged between the upper and lower endplates. The linkage block can include a plurality of linkages and a shear pin disposed at a respective proximal end of each of the linkages. The device can include a drive screw extending through the wedge and linkage blocks. The drive screw can be configured to rotate and drive the wedge block to expand the upper and lower endplates of the structural body from the closed position to an intermediate position. Additionally, the drive screw can be further configured to rotate and drive the linkage block to expand the upper and lower endplates of the structural body from the intermediate position to an open position.

Abstract: A spine implant for an ALIF procedure includes anchoring members being either a bone screw or flexible barb, each having a head on one end of a shaft, and a tip on another end of the shaft. The spine implant includes a porous cage having a front, rear, central cavity, and three angled bores in the front that extend into the central cavity configured to receive one of the plurality of anchoring members such that the tip of the anchoring member extends from one or another side of the cavity with its head retained in the front. The spine implant further includes two retention members configured for insertion into the front such that a portion of the two retention members are positioned over the heads of two, adjacent anchoring members to inhibit bone anchor backout via cam action between the retention member and the heads of the anchoring members.

Abstract: A bone graft delivery system can include an elongate tube and a handle having a trigger and a ratcheting mechanism. The trigger is actuated to deliver bone graft material through the tube. The bone graft delivery system can further include a distal tip at a distal end of the tube. The tip has one or more openings to deliver the bone graft material to a desired location and includes a surface suitable to act as a rasp for decorticating bone. A method for delivering bone graft material to a desired surgical location includes providing a bone graft delivery device, positioning the device adjacent the surgical location, decorticating bone, and delivering bone graft material to the surgical location.

Abstract: A bone graft delivery system includes a rasp having an elongate body extending between a proximal end and a distal end, a lumen extending through the elongate body and configured to receive bone graft material, a rasping surface removably couplable to the distal end of the elongate body and configured to decorticate bone material of a patient, and one or more openings configured to deliver bone graft material from the lumen.

Abstract: The present invention discloses a system and method for motion recognition and control of a prosthetic device. The system of the present invention uses a movement detector for detecting dimensional motion of a non-disabled physical appendage and generating motion information based on this detecting. The system further includes a microcontroller adapted to be connected to the movement detector for receiving and processing the motion information transmitted from the one or more movement detectors. The system controls a prosthetic device which has actuators that are configured to actuate motion of the prosthetic device based on the processing of the motion information.

Abstract: Embodiments herein relate to socket liners for prosthetic systems and prosthetic systems including the same. In an embodiment, a socket liner for a prosthetic system is included having a polymeric wall member defining an interior volume. The polymeric wall member having an inner surface bordering the interior volume and an outer surface. The polymeric wall member can include an anterior side, a posterior side, a first lateral side and a second lateral side the second lateral side opposite the first lateral side. A plurality of horizontal ridges can be disposed on the inner surface of the polymeric wall member on the first lateral side and the second lateral side. A plurality of vertical channels can be disposed on the inner surface of the polymeric wall member on the anterior side and the posterior side. Other embodiments are also included herein.

Abstract: The techniques of this disclosure generally relate to a modular stent device that is deployed via supra aortic access through the brachiocephalic artery. The modular stent device is a base or anchor component to which additional modular stent devices can be attached to exclude diseased areas of the aorta while at the same time allowing perfusion of the left common carotid artery and the left subclavian artery.

Abstract: A vascular stent conveying system includes a housing, an outer cannula, a cleaning tube, an inner cannula, and a driving assembly. The outer cannula is located outside the housing and is connected to a first end of the housing. The cleaning tube is connected to a second end of the housing, a first end of the cleaning tube is located in the housing, and a second end of the cleaning tube extends out of the housing. A part of the inner cannula is located in the housing, a first end of the inner cannula extends into the outer cannula, and a second end of the inner cannula extends from the first end of the cleaning tube to a tube chamber of the cleaning tube. A part of the driving assembly is located in the housing, and operably engaged with a part of the inner cannula located in the housing.

Abstract: An oral weight control device that inhibits the mastication and swallowing of food is provided. The oral weight control device is a dental appliance that includes upper and lower retainers, where each retainer covers the lingual, palatal and buccal side of the teeth to inhibit mastication of food. The dental appliance further includes left and right flexible food barriers extending from the upper retainer to the lower retainer on the lingual side of the teeth to prevent food that a user may attempt to masticate between the upper and lower retainers from being passed to the tongue of the user to ingest. The upper and lower retainers may be customized to fit on each user and may cover all the upper and lower teeth of the wearer on the lingual, palatal and buccal sides of the teeth. The retainers may be removable or semi-permanently secured to the teeth.

Abstract: An attachment system for an orthopedic brace incorporates at least one cinching system assembly having a knob rotatable in a first direction and a second direction. At least one cinching plate is engaged by the knob for rotation in the first direction in a first orientation and transitions to a second orientation upon rotation in the second direction. A ratchet wheel is engaged by the cinching plate in the first orientation for rotation in the first direction. At least one ratchet arm engages the ratchet wheel for ratcheting operation and is engaged by the cinching plate in the second orientation for disengagement from the ratchet arm. A shaft is rotated in response to rotation of the ratchet wheel and a strap is extendible from and retractable on the shaft upon rotation of the shaft.

Abstract: Provided herein is a device for reinforcing the lower body during the performance of a compound weightlifting exercise including at least two thigh bands, each defining an opening for a wearer's thigh, at least two biasing straps, each biasing strap having a proximal end and a distal end, each biasing strap connected at the distal end thereof to one of the at least two generally circular thigh bands, and a waist portion connected to the proximal end of each biasing strap. When worn, each of the biasing straps extends between the waist portion and the thigh bands, over one of the wearer's buttocks and a rear portion of the wearer's thigh.

Abstract: An ostomy bag has an inlet leading to a waste collection space defined by two opposing surfaces of two walls. The opposing surfaces are configured to separate on the introduction of waste through the inlet and in at least one of the walls there is at least one corrugation.

Abstract: A thermal control unit controls the temperature of a fluid delivered to one or more thermal transfer devices (e.g. thermal pads) in contact with a patient. The thermal control unit generates thermal data while being used to treat the patient and is adapted to receive thermal history data previously generated by a different thermal control unit in the treatment of that patient. Both the current and previous thermal data are displayable on the thermal control unit currently being used, thereby giving the caregiver a complete picture of the thermal history of the patient. The thermal control unit may also be adapted to transmit its thermal data, as well as the thermal history data previously received from the other thermal control unit, to still another thermal control unit. The thermal history data transfer may take place via a cable, wirelessly, by a portable flash drive, or by other means.

Abstract: Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange.

Abstract: A gastrointestinal stimulation devices including a random stimulation delivery mechanism(s), configured to provide stimuli to a bodily tissue in a vicinity of the stimulation capsule, the provided random stimuli being characterized by a stimulation parameter, and a control circuitry in communication with said physical stimulation delivery mechanism, and configured to set and alter the stimulation parameter non-systematically, thereby altering the characterization of the stimuli provided to the bodily tissue. The algorithm may be patient tailored, and may have a learning machinery which responds to data being received from the patient.

Abstract: Disclosed are devices and methods for body temperature management using a heat transfer catheter carrying a heat transfer fluid to heat or cool a desired, focused portion of a patient's body. In accordance with certain aspects of the invention, the heat transfer catheter may include hollow nodes that have greater rigidity than the remainder of the catheter to aid in placement of the heat transfer catheter within and navigation of the desired portion of the patient's body. Methods of using such heat transfer catheter to effect temperature management of the patient's body are also disclosed.

Abstract: Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.

Abstract: An eye treatment system having a handpiece, a console, a cassette, and a pump formed by the engagement of the cassette with the console. The pump having a head having a plurality of projections disposed to rotate about an axis, a ramp disposed near the rotating projections, and a resilient channel configured to transfer fluid when engaged by the ramp and the plurality of projections. The ramp having an entrance, a central, and an exit portion. The entrance portion has an arcuate extent over which the projections close the channel as the head rotates. The central portion has an arcuate extent over which the channel is sealed by the projections as the head rotates. The exit portion has an arcuate extent over which the projections open the channel as the head rotates. The arcuate extent of the entrance portion is unequal to the arcuate extent of the exit portion.

Abstract: The invention relates to glaucoma pump implant (100) developed for use in reducing intra ocular pressure of glaucoma patients. The invention particularly relates to a glaucoma pump implant (100) that allows the glaucoma pump implant (100) to act as an active pump by utilizing diameter changes of pupil (210) and iris (220) caused by light variations.

Abstract: An ophthalmic illumination method and system with a head-up display imaging system is provided wherein a therapeutic light is generated by a first laser light source configured to generate therapeutic light and a near-infrared wavelength of an alignment pattern is generated by a second laser light source, where the therapeutic light is directed upon an eye to be examined or treated in accordance with the alignment pattern.

Abstract: Technologies are described for monitoring efficacy of laser treatment through cell lysis determination. Current methods for removing diseased tissue may include directing laser treatment toward cells in a treatment area. The laser treatment may induce lysis of the cells without any visual indication of the lysis occurring. According to some examples, a treatment system may direct a pair of laser pulses to cells in a treatment area. The treatment system may derive a first signal and a second signal based on a detected response to the first and second laser pulse within the pair. A signal processor, according to some examples, may determine a difference between the first signal and the second signal and may modify the laser treatment based on the difference.

Abstract: Active dichoptic perceptual-learning tasks or dichoptic game play have been shown to significantly improve visual acuity of amblyopic children and adults. However, these dichoptic perceptual learning tasks are intensive and repetitive such that non-compliance is high. In contrast, the invention provides dichoptic perceptual learning in a manner that the user maintains its use and compliance is increased. Further, compliance becomes automatic if the user performs tasks in a normal manner and “forgets” that they are actually undergoing treatment as it is integrated with minimal disruption to their life and activities. Accordingly, a methodology exploiting complementary dichoptic simulation is presented.