Abstract: A medical device (100) determines a cardiac output-dependent parameter (105) of a patient to be treated. A reception module receives a pulsatile signal (112) that indicates a blood pressure course (114). A storage module provides a model rule (122), describing an assignment between a number of predefined blood pressure course parameters (124) and the cardiac output-dependent parameter (105) to be assigned. A read-out module reads out the number of predefined blood pressure course parameters from the indicated blood pressure course and provides corresponding read-out measured values (132). A calculation module calculates and outputs an output value (142) for the cardiac output-dependent parameter (105) to be assigned based on the read-out measured values for the number of predefined blood pressure course parameters using the model rule, which is based at least partially on an end-systolic state (116) of a respective blood pressure pulse (115) of the blood pressure course.

Abstract: A system and method for leak correction and normalization of in-ear pressure measurement for hemodynamic monitoring are disclosed. The system includes an acoustical assembly and a data analysis system. The acoustical assembly includes an earbud system that forms an earbud seal with an ear canal of an individual, where the earbud system includes an earbud with an in-ear acoustic sensor that detects acoustic signals in the ear canal. The acoustic signals include audible signals and infrasonic signals. The data analysis system receives the acoustic signals from the earbud system, identifies hemodynamic pressure signals from a body of the individual included within the infrasonic signals, and identifies signal characteristics of the pressure signals over time. The data analysis system can then correct the hemodynamic pressure signals for effects caused by leaks in the earbud seal based upon changes to the signal characteristics over time.

Abstract: A viscoelastic characteristics acquisition device is a device that acquires viscoelastic characteristics of a blood vessel of an inspection target, and includes a pulse wave acquisition unit that acquires a time waveform corresponding to a volume pulse wave of the inspection target, a spectrum acquisition unit that acquires a volume pulse wave spectrum by performing Fourier transform on the time waveform, an input unit to which values corresponding to maximum blood pressure and minimum blood pressure of the inspection target are input, and an analysis unit that acquires the viscoelastic characteristics on the basis of the values corresponding to the maximum blood pressure and the minimum blood pressure and the volume pulse wave spectrum at a frequency equal to or higher than a frequency corresponding to the pulse of the inspection target.

Abstract: Systems and methods for optimizing sensor pressure in blood pressure (BP) measurements using a wearable device are provided. An example method includes recording photoplethysmogram (PPG) data using a PPG sensor of a wearable device while a pressure applied by the PPG sensor to a blood artery of a user is gradually increasing, monitoring a pulsating parameter associated with the PPG data, determining that the pulsating parameter has passed a critical value, in response to the determination, causing the increase of the pressure to stop, recording further PPG data using the PPG sensor and electrocardiogram (ECG) data using input plates of the wearable device, analyzing the further PPG data and the ECG data to determine a pulse transit time (PTT), a pulse rate (PR), and a diameter parameter, and determining, using a pre-defined model, a BP based on the PTT, the PR, and the diameter parameter.

Abstract: Methods, systems, and devices for illness detection are described. A method may include receiving heart rate variability (HRV) data associated with a user from a wearable device, the HRV data collected via the wearable device throughout a first time interval and a second time interval subsequent to the first time interval. The method may include inputting the HRV data into a classifier, and identifying a satisfaction of deviation criteria between a first subset of the HRV data collected throughout the first time interval and a second subset of the HRV data collected throughout the second time interval. The method may include causing a graphical user interface (GUI) of a user device to display an illness risk metric for the user based on the satisfaction of the deviation criteria, the illness risk metric associated with a relative probability that the user will transition from a healthy state to an unhealthy state.

Abstract: There are provided a maternal and fetal monitoring device and a display device for monitoring device including fetal heart rate acquisition means configured to acquire a fetal heart rate, labor pain intensity acquisition means configured to acquire a maternal labor pain intensity, fetal bioelectric signal acquisition means configured to acquire a fetal bioelectric signal, and display means capable of simultaneously displaying a cardiotocogram that displays the fetal heart rate and the labor pain intensity side by side on the same time axis over time as a graph and a fetal bioelectric signal diagram displaying the fetal bioelectric signal, and optimizing and displaying, together with the cardiotocogram, the fetal bioelectric signal diagram and the like closely related to these pieces of information.

Abstract: This specification describes methods of performing ECG analyses. In one approach, the system receives an ECG recording for a first duration, automatically performs a first analysis of the ECG recording for the first duration to detect events with reference to each of a plurality of arrhythmias, generates a GUI where areas within the GUI are designated for displaying detected events for each of the arrhythmias and enables a user to select at least one ECG segment of a second duration of the ECG recording. In response to the user's selection of the at least one ECG segment, the system presents the user with at least one option, and in response to the user's selection of the option, the system performs a second analysis of the ECG segment of the second duration and displays at least one output corresponding to the second analysis.

Abstract: A sensor device for potential and/or impedance measurements on a body of a user, including a central electronic unit and at least a first sensor and a second sensor. Each sensor is connected to the central electronic unit by a one-wire connector. Each sensor includes a current electrode and a potential electrode destined to be in contact with a surface of the body. The master includes a master current source configured to circulate a master current in the one-wire connector, the current electrode of the at least first and second sensors and the body, when the sensors are in contact with a surface of the body. Each sensor includes a harvesting device configured to harvest energy from the circulating master current in a powering frequency band.

Abstract: Methods of determining an index of vessel and heart function are disclosed. The methods determine the maximum volume and rate of change of volume so that an efficiency of the heart can be determined. Conductance readings indicative of the heart can be taken from a variety of locations such as the lumen of a vessel, the lumen of a heart, the pericardial space, and the epicardial surface. Said conductance readings are then used to determine the efficiency of the heart.

Abstract: Disclosed are a screening apparatus using a multi-channel array electrode probe and a method of operating the screening apparatus, wherein the screening apparatus includes a probe inserted into the inside of the human body and including a plurality of electrodes in contact with any one portion of the inside and an endoscope camera for photographing the portion; a location identifier for identifying a location in contact with the electrodes in an image photographed by the endoscope camera; an electrical property measuring device for measuring the electrical properties of the identified location; a mapping processor for mapping the measured electrical properties to an electrical model for the internal tissue; and a visualization information generator for, based on the mapping results, generating visualization information for visualization of the degree of deformation of the tissue with respect to the measured electrical properties.

Abstract: A method for use in analysing impedance measurements performed on a subject, the method including, in a processing system, determining at least one impedance value, representing the impedance of at least a segment of the subject, determining and indicator indicative of a subject parameter using the at least one impedance value and a reference, and displaying a representation of the indicator

Abstract: Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of tracking and locating the same are provided.

Abstract: A respiration rate measurement apparatus including a plurality of sensors for concurrently generating temperature, pressure and acoustic data representing one or more successive breaths and a method of generating fusion data from the plurality of data streams as a weighted average based on determined correlation coefficients and calculation of a respiratory rate.

Abstract: An apparatus for static weight-bearing assessment of foot and lower limb abnormalities, the apparatus comprising: a platform configured to support at least part of a patient's foot; and an actuator arrangement configured to control a displacement of the platform.

Abstract: The present application relates to a method for recognizing motion pattern of human lower limb and prostheses, orthoses, or exoskeletons thereof. The method may comprise collecting motion data; inputting the collected motion data and corresponding limb motion patterns into a classifier or pattern recognizer to train the classifier or the pattern recognizer; and inputting the motion data of the limb obtained in real time by the sensor into the trained classifier or the trained pattern recognizer to recognize a motion pattern of the limb.

Abstract: A gait measurement system includes: a locus calculation device that detects at least one gait phase from acceleration data measured by an inertial measurement unit, calculates velocity data by subjecting the acceleration data to time integration, calculates correction amounts associated with each of the gait phases using the gait phases and the velocity data, calculates correction velocity data by subtracting the correction amounts from the velocity data associated with each of the gait phases, and calculates locus data by subjecting the calculated correction velocity data to time integration; and an index calculation device that calculates a gait index, using the locus data calculated by the locus calculation device.

Abstract: Calibration of a sensing device is provided. The sensing device includes a sensor configured to sense a condition. In the sensing device, a voltage-dividing resistance and a reference voltage of an analog-to-digital converter are set to configure a quantization range of the analog-to-digital converter given characteristics of the sensor. During calibration, a binary search is performed between lower and upper limits of the voltage-dividing resistance, which is a variable resistance, to find the resistance of the voltage-dividing resistance at which the sensing device is operated.

Abstract: The present invention is directed to enabling the capturing of an image to facilitate the comparison between affected parts. An imaging apparatus includes an image capturing unit, and a control unit configured to perform control to, in a case where posture information regarding an object obtained when an image of an affected part of the object has been captured in the past is acquired and the image capturing unit captures an image of the affected part of the object, notify a user of the posture information regarding the object and inclination information regarding the imaging apparatus.

Abstract: Elderly people suffer from health issues, and timely detection can save lives. State of the art techniques either make certain assumptions or require clinical data in order to perform the frailty detection, which affects the quality as well as cause inconvenience to the users. The disclosure herein generally relates to patient monitoring and, more particularly, to frailty detection using pedometer sensor data, PIR sensor data, and door sensor data. The system determines activity levels of the user being monitored, based on data from the pedometer sensors, PIR sensors, and door sensors, and based on the determined activity levels, further determines whether the user has frailty or not.

Abstract: A method and device enable the detection of pressures induced by an infant's sucking actions on a mouthpiece. The method and device also enable the detection of head movements of the infant. The method and device transmit the data associated with the detected pressures and/or the data associated with the detected head movements to another device for evaluating the hearing sensitivity of the infant.

Abstract: Diabetes prediction using glucose measurements and machine learning is described. In one or more implementations, the observation analysis platform includes a machine learning model trained using historical glucose measurements and historical outcome data of a user population to predict a diabetes classification for an individual user. The historical glucose measurements of the user population may be provided by glucose monitoring devices worn by users of the user population, while the historical outcome data includes one or more diagnostic measurements obtained from sources independent of the glucose monitoring devices. Once trained, the machine learning model predicts a diabetes classification for a user based on glucose measurements collected by a wearable glucose monitoring device during an observation period spanning multiple days. The predicted diabetes classification may then be output, such as by generating one or more notifications or user interfaces based on the classification.

Abstract: The Diabetic Glucose Monitoring Smart Watch, in conjunction with the “Save a Life, Link a Buddy” smart phone application, is designed for any person with Type I or Type II Diabetes. The smart watch will monitor the blood glucose levels of the wearer through a continuous glucose monitor and will alert the user in real-time if glucose levels reach a danger zone designated by the user during set up. If the wearer is unresponsive to the alert for over 60 seconds, the linked application (“Save a Life, Link a Buddy) will then notify the “buddies” assigned by the user. This alert will appear on the “buddies” phone similar to an Amber-Alert that needs to be turned off manually.

Abstract: A device, a system for the device and a set of methods used to extract pulse wave features and select an optimal combination of these features for calculating and determining the blood glucose level and discriminating between different sources of blood glucose level changes in a subject, wherein the different blood glucose level changes are selected among the type of nutrients, sport activities, stresses and fatigue or a combination thereof. The system is designed for accurately obtaining, measuring, registering and interpreting the pulse to determine the blood glucose level of a subject. By collecting pulse wave features, selecting those that are most significant and developing algorithms, the device and its method calculates the user's blood glucose levels and discriminates between different sources of blood glucose level changes of the subject.

Abstract: Methods and devices include automated coaching for management of glucose states by receiving a user's glucose levels using a continuous glucose monitoring (CGM) device, determining a time in range (TIR) value, determining a TIR state, receiving a glucose variability (GV) value, determining a GV state, determining a starting state based on the TIR state and the GV state, determining that the starting state corresponds to a non-ideal state, generating an optimized pathway to reach an ideal state based on one or more account vectors such as addressing self-management behavior including food, activity, and medication use. The optimized pathway may further be based on computer detection and classification of significant events of interest over time.

Abstract: [Problem] To provide a device for measuring the concentration of lipid by a noninvasive lipid measurement and a method therefor. [Solution] The present invention includes: an irradiation unit that irradiates a living body with light with the angle between the surface of the living body and the optical axis being a predetermined angle of 45 to 175°; a light intensity detection unit that is positioned at a predetermined distance from the irradiation unit and measures light intensity reflected from the living body; and a control unit that calculates the amount of turbulence of blood flow on the basis of the light intensity and calculates lipid concentration on the basis of the amount of turbulence of blood flow.

Abstract: A concentration measurement apparatus includes a light input unit for inputting measurement light to a measurement target portion, a light detection unit for detecting the measurement light propagated inside the measurement target portion, and generating a detection signal according to an intensity of the measurement light, and a calculation unit for obtaining hemoglobin-related information based on the detection signal. The calculation unit performs filter processing of extracting a component derived from respiration among frequency components included in the detection signal, the hemoglobin-related information, or a numerical value appearing in a calculation process of the hemoglobin-related information for obtaining the hemoglobin-related information in a vein of the measurement target portion.

Abstract: An evaluation apparatus includes a display; a gaze point detection unit configured to detect a position of a gaze point of a subject; a display controller configured to display an evaluation image including a main target image, sub target images, and an instruction information to gaze at the main target image; a region setting unit configured to set determination regions for the sub target images; a determination unit configured to determine whether the gaze point is present in the determination regions based on the position of the gaze point; an arithmetic unit configured to measure an arrival time from a predetermined time to a first arrival time of the gaze point at the determination regions based on a result of the determination unit; and an evaluation unit configured to obtain an evaluation data of the subject based on an average or a total value of the arrival times.

Abstract: Systems and methods for estimating emotional states, moods, affects of an individual and providing feedback to the individual or others are disclosed. Systems and methods that provide real time detection and monitoring of physical aspects of an individual and/or aspects of the individual's activity and means of estimating that person's emotional state or affect and change to those are also disclosed. Real time feedback to the individual about the person's emotional change, change or potential change is provided to the user, helping the user cope, adjust or appropriately act on their emotions.

Abstract: Systems and methods for estimating emotional states, moods, affects of an individual and providing feedback to the individual or others are disclosed. Systems and methods that provide real time detection and monitoring of physical aspects of an individual and/or aspects of the individual's activity and means of estimating that person's emotional state or affect and change to those are also disclosed. Real time feedback to the individual about the person's emotional change, change or potential change is provided to the user, helping the user cope, adjust or appropriately act on their emotions.

Abstract: A computer-implemented method for adaptive behavioral training includes presenting a first visual training area to a user in a visual presentation. The visual presentation is displayed in a coordinate space and the first visual training area is defined by a first set of coordinates in the coordinate space. Measurement data is collected while the first visual training area is presented to the user. This measurement data comprises eye tracking measurement data indicating the user's gaze with respect to the first visual training area. Based on the measurement data, a second visual training area is selected. This second visual training area is defined by a second set of coordinates in the coordinate space that are different than the first set of coordinates. The second visual training area is then presented to the user in the visual presentation.

Abstract: In at least one embodiment, a system for performing biometric evoked response monitoring and feedback for a vehicle is provided. The system includes a plurality of sensors and at least one controller. The plurality of sensors may be positioned about a main cabin of the vehicle and each sensor is configured to provide a first signal indicative of a measured electromagnetic characteristic of an anatomical feature of a driver for the vehicle in response to an alert being issued to the driver. The at least one controller is configured to receive the first signal and to determine a stimulus response and an attentiveness response of the driver based on the measured electromagnetic characteristic of the anatomical feature of the driver.

Abstract: It is a principal goal of the present invention is to provide a uroflowmetry device for calculating uroflowmetry data (flow rate and other data) associated with urination sessions. The invention is an in-toilet uroflowmetry device, which unlike existing stand-alone and in-toilet devices is not touched by the urine stream, and un-like with existing in-toilet devices, the toilet is useable for all normal functions by men and women. The invention also provides new data not provided by existing uroflowmetry devices. The present invention is a device comprised of an electronic open loop belt with video cameras, a single-board computer (SBC), LEDs and various sensors to start the video cameras and control the LEDs. The video data is transferred wirelessly to a website where image processing is performed on the video data, followed by computations of flow rate and additional uroflowmetry data.

Abstract: A surgical method aids identification of nerves in a body to help prevent damage to the nerves during surgery to the body proximate the nerves. An electrode introduced to within a body cavity through a catheter is placed proximate a nerve within the body cavity by a laparoscopic or robotic device. An exploratory probe placed in the body cavity is selectively placed along a presumed pathway of the nerve to provide an electrical signal through the nerve to the electrode. An analyzer interfaced with the electrode analyzes the electrical signal received at the electrode to determine the proximity of the exploratory probe to the nerve, allowing mapping of the nerve pathway through the body cavity.

Abstract: Embodiments provide a wearable apparatus for acquiring electrophysiological signals of a living being. The apparatus includes a textile carrier, at least two dry electrodes attached to an inside of the textile carrier and at least two adjustable straps attached to the textile carrier that allow to adjust the wearable apparatus to a body of the living being and a contact pressure of the at least two dry electrodes to a skin of the living being.

Abstract: Arrhythmic foci and other driver sites can be mapped using a multi-dimensional catheter. For instance, using a clique of three or more electrodes on the multi-dimensional catheter, an electroanatomical mapping system can identify a maximum bipolar voltage and an average unipolar voltage. The ratio of the average unipolar voltage to the maximum bipolar voltage can be interpreted as an indication of whether a cardiac location is an arrhythmic focus. Alternatively, an evaluation region can be defined about location in the patient's heart. The evaluation includes a plurality of rods, each associated with a respective E-field loop having a respective maximum and minimum amplitude bipole axes, with the rods being defined by the maximum amplitude bipole axes. For a sufficient number of rods within the evaluation region, a focus score for the evaluation region can be computed to reflect rod orientation consistency within the evaluation region.

Abstract: A catheter comprising an elongated catheter body, and an electrode assembly distal of the catheter body, the assembly comprising a plurality of spines, wherein each spine has a distal end that is connected to the distal end of at least one other spine, wherein each spine has an electrode-carrying portion, the electrode-carrying portions of all spines of the assembly being in a single common plane, and wherein all spines of the assembly have a uniform exposed total length.

Abstract: According to an aspect, there is provided switch circuitry (1) for controlling power supplied to a fluid monitoring unit (4). The switch circuitry (1) comprises: a sensor (2) configured to detect fluid derived from the skin of a user and to generate a detection signal in response to detection of fluid; and a controller (3) configured to receive the detection signal, to generate a wake-up signal in accordance with the detection signal, and to supply the wake-up signal to a switch (6) controlling the power supply to the fluid monitoring unit (4) so as to activate the switch (6) and wake the fluid monitoring unit (4), wherein, optionally, the fluid is sweat. According to another aspect, there is provided method of controlling power to a fluid monitoring unit.

Abstract: Systems and methods for assessing the condition of a heart of an individual. A system obtains electrocardiogram (ECG) data that describes a result of an ECG of the individual. The ECG data can be provided to a machine-learning model, which processes the data and generates an output indicative of the condition of the heart. The output relates to a level of troponin in a bloodstream of the individual. The system can then provide the output of the machine-learning model to a post-processing resource.

Abstract: The present system allows for the physician to change the relative height of the signal to allow for examination of details of the signals, while maintaining an ability to interpret signal voltage levels absolutely based on color or other secondary mechanism beyond signal height. The disclosed system and method provide for faster and more accurate analysis based upon the color of the signal. The signal height may change, such as to view, display, or examine details of the signal, while the colors of the display do not. The color scale of the signal provides an absolute scaling of the signal regardless of the displayed height.

Abstract: Embodiments of the present disclosure provide a mobile electrocardiogram (ECG) sensor comprising an electrode assembly comprising electrodes, wherein the electrode assembly senses heart-related signals when in contact with a body of a user, and produces electrical signals representing the sensed heart-related signals. The ECG sensor further comprises a processing device, operatively coupled to the electrode assembly, the processing device to provide the sensed heart-related signals to a machine learning module trained to predict a twelve-lead QT interval (QTc) value from the mobile ECG sensor comprising less than twelve leads. The ECG sensor also comprises a housing containing the electrode assembly and the processing device.

Abstract: An implantable medical device is configured to determine a first atrial arrhythmia score from ventricular events sensed by a sensing circuit of an implantable medical device and determine a second atrial arrhythmia score from an intraventricular signal comprising atrial mechanical event signals attendant to atrial systole and produced by a sensor of the implantable medical device. An atrial arrhythmia is detected based on the first atrial arrhythmia score and the second atrial arrhythmia score.

Abstract: Disclosed herein are a neural signal feedback system and method. The neural signal feedback system includes: a microelectrode array unit configured such that a plurality of microelectrodes is disposed on a substrate and such that one microelectrode, which is a reference electrode, and corresponding electrode groups including other microelectrodes located at different same distances from the reference electrode are set; and an analysis and determination unit configured to compare neural signal values, measured in the microelectrode array unit, with a preset reference value, and to determine whether to apply the electrical stimulation of the microelectrode array unit. The analysis and determination unit performs re-measurement after the application of electrical stimulation, and repeats the application of electrical stimulation and measurement until the measured values reach the reference value.

Abstract: A system for testing a patient's taste recognition and sensitivity. The system includes a sample selector for dispensing taste test samples to the patient, and a test controller configured to determine which taste test sample to dispense to the patient. The test controller is arranged to receive taste test results from the patient associated with the dispensed taste test samples, and determine on the fly which taste test sample to dispense next, based on the received taste test results. Once a plurality of taste test samples have been dispensed to the patient in this manner, the test controller may then determine a taste sensitivity (e.g. threshold) for the patient based on the received taste test results.

Abstract: A method of determining that an absence of suspicion of neurological injury is indicated in a subject is disclosed. The method involves prompting the subject to engage in three or more of the following neurological assessments: a) Reading Saccades, b) Near/far accommodation using Hart charts of different font sizes; c) Brock string, d) Maddox rod, e) closed-eye turns, f) Near Point of Convergence, and g) PERRLA with consensual reflex. The data from the neurological assessments is used to determine that an absence of suspicion of neurological injury is indicated in the subject.

Abstract: A biological information acquisition device is provided that enables a cognitive function test to be received as part of routine healthcare management. Cognitive function test information is provided. Subsequently, biological information is acquired as an interference task. After acquiring the biological information, answers from the user to the previously provided cognitive function test information are checked.

Abstract: A method for identifying changes in an epilepsy patient's disease state, comprising: receiving at least one body data stream; determining at least one body index from the at least one body data stream; detecting a plurality of seizure events from the at least one body index; determining at least one seizure metric value for each seizure event; performing a first classification analysis of the plurality of seizure events from the at least one seizure metric value; detecting at least one additional seizure event from the at least one determined index; determining at least one seizure metric value for each additional seizure event, performing a second classification analysis of the plurality of seizure events and the at least one additional seizure event based upon the at least one seizure metric value; comparing the results of the first classification analysis and the second classification analysis; and performing a further action.

Abstract: Systems, methods, and other techniques for monitoring, including non-invasive monitoring, of biological markers based on the interaction, temporal association, or coincidence of brain activity and periphery activity in a mammal are provided. Systems and methods for generating a behavioral state-independent representation of cardiac activity and for identifying cardiac events and/or brain-periphery, e.g., brain-cardiac, temporal associations useful as biomarkers of disease such as, e.g., neurologic disease, in a mammal are also provided.

Abstract: An apparatus for estimating bio-information according to an embodiment of the present disclosure includes a first sensor configured to obtain a fingerprint image of a finger of the user; a second sensor configured to measure a force or a pressure applied by the finger; and a processor configured to obtain, based on the fingerprint image, a first feature value related to pulse waves and a second feature value related to skin elasticity; obtain a third feature value based on the force or the pressure; and estimate the bio-information of the user based on the first feature value, the second feature value, and the third feature value.

Abstract: In some embodiments, a wound monitoring and/or treatment system includes a dressing and/or housing configured to be placed in or over wound and/or skin of a patient, sensor configured to measure patient data, and controller configured to receive patient data measured by the sensor, selectively store at least some of the patient data in a memory, and communicate, via a transceiver, at least some of the data stored in the memory to an external computing device. The controller can be configured to, in response to determining that the dressing and/or housing is placed in or over the wound and/or skin, communicate, via the transceiver, to the external computing device a confirmation. The controller can be configured to, in response to receiving, via the transceiver, from the external computing device an authorization to collect patient data, store at least some of the patient data measured by the sensor in the memory.

Abstract: A wound dressing for wireless communication with a transceiver includes a radio-frequency antenna circuit disposed on a flexible substrate, and an electrochemical moisture sensor circuit disposed on a surface of the flexible substrate. An adhesive is provided to attach the wound dressing skin of a user. The electrochemical moisture sensor is arranged between the adhesive and the flexible substrate.