Abstract: Devices and methods for standardizing breathing effort in subjects are disclosed. An exemplary device has an exhaust housing having a proximal portion that defines a port and an opposed distal portion that defines inspiration and expiration pathways. The distal portion has a distal end surface, and the inspiration and expiration pathways are in fluid communication with the port and extend, respectively, to inlet and outlet openings defined in the distal end surface. An airflow adjustment plate, which defines openings having varying sizes, is rotatably coupled to the distal portion of the exhaust housing. Rotation of the airflow adjustment plate relative to the exhaust housing among a plurality of rotational positions, with a respective opening of the airflow adjustment plate being positioned in alignment with the inlet opening at each position, thereby increasing or decreasing resistance to air flow through the inlet opening.

Abstract: Monitoring systems and methods for measuring one or more physiological parameters of an individual. More particularly, systems and methods for monitoring one or more parameters or other data relating to the breath volume of an individual, determining various breath characteristics or indicators based on breath volume data, and providing a meaningful display of the breath characteristics or indicators for easy and quick identification and/or diagnosis of breathing-related or other health conditions.

Abstract: A method to detect and analyze cough parameters remotely and in the background through the user's device in everyday life. The method involves consecutive or selective execution of 4 stages, which solve a variety of the following tasks: Detection of coughing events in sound, in environmental noise. Separation of the sound containing the cough into the sound of the cough and the rest of the sounds, even when extraneous sounds occurred during the cough. Identify the user by the sound of the cough to prevent analyzing the sounds of the cough that do not belong to the user (for example when another person coughs nearby). Assessment of cough characteristics (wet/dry, severity, duration, number of spasms, etc.). The method can work on wearable devices, smart devices, personal computers, laptops in 24/7 mode or in a selected range of time, and has a high energy efficiency.

Abstract: The present inventive concept relates to a non-face-to-face health status measurement system and method through a camera-based vital sign data extraction and an electronic questionnaire, providing a system and a method for monitoring various infectious diseases and enabling rapid response to the occurrence of diseases and infectious diseases by measuring a health status of a user in non-face-to-face through a vital sign data including heart rate, respiration rate, oxygen saturation, etc. extracted by using color information of a face image taken with a camera and results of an electronic questionnaire performed online.

Abstract: A digital topographic model of the luminal surface is generated by projecting an optical pattern on the luminal surface from the first location within the lumen. At least a portion of the projected pattern is detected from a second location within the lumen which is based apart from the first location. The dimensions of the luminal wall can be measured by triangulation in order to produce the digital topographic model of the body lumen.

Abstract: The present invention presents a device for calculating, during one step or each successive step of the gait of a subject, the push-off P0 of the subject, which is the power per kilogram released by the ankle push-off moment, which comprises: at least one inertial measurement unit (1A, 1B) on one foot of the subject, the inertial measurement unit (1A, 1B) having: at least one accelerometer to measure the vertical and antero-posterior accelerations and/or at least one gyroscope to measure the medic-lateral angular speed data {acute over (?)} during the gait, storage and calculation means (2A) connected to the Inertial measurement unit (1A, 1B), configured to calculate: for the foot, and for the step or each successive step of the gait:—the time of the heel-off and the time of the toe-off,—the push-off P0, by the Euler's equation stating that the sum of moments acting on the foot taken as a rigid body, being equal to the rate of change of the angular momentum of the foot, with the calculation of the push-off P0

Abstract: Surgical systems and methods to interact with a limb of a patient held by a limb holder. An instrument is configured to apply a force externally to the limb held by the limb holder, One or more controllers measure an extent to which the limb moves relative to the limb holder in response to the force applied externally to the limb by the instrument. The one or more controllers generate, based on the measured extent, a notification relating to physical adjustment of one or both of the limb and the limb holder.

Abstract: A rehabilitation system includes left-hand and right-hand rehabilitation apparatuses that cooperate with programming instructions operating on a patient computer and on a therapist computer that is remote from the patient computer. Each apparatus includes a hand section with movement sensors supported on the backside of the hand of the patient from which patient hand movements can be derived, finger sections moveable relative to the hand section with sensors to track flexing and movement of the finger sections relative to the hand, a wrist section supporting vital sign sensors communicating with the patient, and adjustable resistive elements applied to the finger or hand movements. The system enables a therapist to communicate target movements to the user, as well as allowing the comparison between patient movements conducted at different times or with different hands. Sensor data can be used to measure patient performance that is provided to the patient and the therapist.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: In vivo monitoring devices and systems for enzymes and/or analytes including devices having a reactant reservoir are provided.

Abstract: A method, apparatus and device for obtaining a blood glucose measurement result. A neural network model is trained by using the following method, so as to obtain a trained first neural network model: acquiring a first invasive blood glucose measurement result of a tested object (101); forming a group of new training data by means of same and characteristic values of the most recent PPG signals of the tested object (102); training the neural network model with the training data, so as to obtain a trained first neural network model (106); and after a group of new PPG signals is acquired, extracting characteristic values of the new PPG signals, and inputting the characteristic values into the trained first neural network model, so as to obtain a target blood glucose measurement result (107).

Abstract: The present invention relates to the non-invasive determination of glucose in blood, in particular to the non-invasive determination of glucose in capillary blood.

Abstract: A method and system for measuring oxygen levels and various blood constituents utilizing a sensor having one or more light sources, and one or more light detectors is disclosed. The system is capable of using data collected by the one or more detectors from a non-monochromatic light source to provide accurate information during motion events occurring with an extremity the sensor. The system is also capable of detecting and providing an alert if the sensor is not properly placed on a patient or becomes disengaged therefrom.

Abstract: An input interface is configured to receive a signal corresponding to a quantity of light that has passed through a living tissue of a subject. A pressurization controller is configured to control a pressurizing operation performed with a pressurization device attached to a body of the subject, thereby changing at least one of a thickness of the living tissue, an amount of blood contained in the living tissue, an amount of cellular interstitial fluid contained in the living tissue, an amount of blood flowing into the living tissue, and an amount of blood flowing out from the living tissue. A processor is configured to acquire, from a temporal change of the signal due to the pressurizing operation, a feature quantity that is used for estimating at least one of a physiological state of the living tissue and a disease state of the subject.

Abstract: Embodiments of the invention provide methods and materials for making analyte sensors having a plurality of layered elements such as amperometric glucose sensors that are used by diabetic individuals to monitor blood sugar concentrations. Embodiments of the invention utilize plasma deposition technologies to form thin films of hexamethyldisiloxane useful in such sensors. Sensors that incorporate the thin film compositions formed by these processes exhibit a number of desirable characteristics.

Abstract: Apparatus and methods for mitigation and control of inflammatory responses during usage of an implantable sensor device. In one exemplary embodiment, the implantable sensor device includes a drug-eluting component configured to release a varying amount of anti-inflammatory substance(s) (such as corticosteroid) over the lifetime of the implant, such as according to a desired elution profile. In one variant, this component is also an analyte-permeable membrane used as part of a detector of the implant. Inhibition of inflammation in the tissue improves availability of analytes (such as oxygen and glucose) to the sensor in addition to reducing fibrous encapsulation. Various modifications to the elution rate, and configuration of the implant, allow optimized control over undesirable effects such as foreign body reactions (FBR) or other inflammatory responses which may reduce usable implant lifetime.

Abstract: The present invention relates to a blood components collection and separation media (1) comprising a substrate (3) having a maximal flow pore size enabling the retention of at least red cells on the surface of the substrate (3), the blood components collection and separation media (1) comprises boundary walls (7) forming a pattern (9) and being made of a hydrophobic resin, and the pattern (9) presenting: a collection zone (91); at least one storage zone (93) aimed at collecting at least one component of the whole blood sample (5); and at least one channel (95) connecting the collection zone (91) to the at least one storage zone (93), the channel (95) forming a bottleneck between the collection zone (91) and the storage zone (93). The present invention further relates to a blood components collection and separation device and a blood components separation and extraction process.

Abstract: Disclosed is a tubing system for use in a blood sampling-blood pressure monitoring system. The blood sampling-blood pressure monitoring system may include a control valve, a reservoir with a plunger, a sampling site, and a blood pressure transducer for measuring the blood pressure of a patient. The tubing system may comprise: a plurality of flexible tubing sections and a plurality of rigid tubing sections. The plurality of rigid tubing sections and flexible tubing sections may be interlinked with one another between the patient and the blood pressure transducer for the blood pressure measurement of the patient.

Abstract: The present invention relates to a method for provision of information on a mental disorder and a device utilizing same, the method for provision of information on a mental disorder being implemented by a processor, and comprising: outputting a stimulus to a subject in order to generate brain waves; receiving brain wave data and brain activity data measured in the subject during outputting the stimulus; and determining whether a mental disorder is present in the subject by using a classification model configured to classify mental disorders on the basis of the brain wave data and the brain activity data.

Abstract: The present subject matter refers a method to evaluate concentration of a living being based on artificial intelligent techniques. The method comprises detecting a continuous increase in concentration of a living being based on an artificial neural network (ANN), The method comprises receiving a parameter of the continuous increase in concentration, determining a first value of the concentration based on a first condition, said first condition defined by increase of the received parameter by more than a first predetermined threshold; and determining a second value of the concentration based on a second condition, said second condition defined by decline in the concentration from the first value by more than a second predetermined threshold.

Abstract: An arousal level prediction apparatus and method are disclosed. The arousal level prediction apparatus obtains first biological information indicating current biological information of the user, obtains first environment information indicating a current environment around the user, and obtains living information of the user indicating an activity history of the user. The arousal level predication apparatus includes a process that calculates a first arousal level indicating a current arousal level of the user based on the first biological information, predicts a second arousal level, which is an arousal level of the user at a certain period of time later, based on the first arousal level, the first environment information and the living information, and outputs the second arousal level.

Abstract: A system for monitoring biometric signals of a user comprising: a garment configured to be worn by the user and comprising a mounting module having an array of connection regions; a set of biometric sensors coupled to the garment and configured to communicate with the array of connection regions to receive and transmit biometric signals indicative of muscle activity of the user; and a portable control module configured to couple to the garment in a first configuration and to decouple from the garment in a second configuration and comprising: a housing comprising an array of openings; a set of contacts, each including a first region that seals at least one of the array of openings and couples to at least one of the array of connection regions in the first configuration, and an electronics subsystem coupled to the housing and in communication with a second region of each contact.

Abstract: A medical electrode device for implantation comprises a carrier formed from an electrically insulating material and defining a surface extending along a plane of extension, and at least one electrode arranged on the carrier for emitting an electrical stimulation signal and/or receiving an electrical sense signal. The at least one electrode comprises first and section wall sections. Said first wall section, in a cross-section along a cross-sectional plane perpendicular to said plane of extension, extends straight along a perpendicular direction with respect to said plane of extension or at an oblique angle with respect to said perpendicular direction, the first wall section in contact with the carrier electrically insulating material. Said second wall section, in said cross-section along said cross-sectional plane perpendicular to said plane of extension, adjoins said first wall section and is curved, the second wall section not in contact with the carrier electrically insulating material.

Abstract: [Object] Proposed are a biopotential measuring apparatus, a biopotential measuring system, and a biopotential measuring method that are capable of suppressing an erroneous determination in determining the quality of a contact state between an electrode and a living body. A biopotential measuring apparatus of the present technology includes an electrode and a controller. The electrode measures a biopotential. The controller determines a quality of a contact state between the electrode and a living body on the basis of a signal amplitude of a signal of a specific frequency.

Abstract: A disposable spiral electrode for a fetal scalp, comprising an electrode fixing column (6), a spiral electrode and an auxiliary electrode (6.1, 6.3) which are on the electrode fixing column (6), a twisted pair (4), an inner sleeve (8), an outer sleeve (1) and an outer sleeve fixing piece, wherein one end of the outer sleeve (1) is inserted into the outer sleeve fixing piece; the electrode fixing column (6) extends out of or retracts into the other end of the outer sleeve (1); one end of the twisted pair (4) sleeved with the inner sleeve (8) is respectively connected to the spiral electrode and the auxiliary electrode (6.1, 6.3), and the other end thereof is led out from within the outer sleeve fixing piece; an outer sleeve (2) in the outer sleeve fixing piece is movably sleeved on an inner sleeve (5) and may move relatively along the axial direction; one end of the outer sleeve (2) is in insertion connection with one end of the outer sleeve (1); a section of an inwardly concave arc (3.

Abstract: A device for determining a physiological or psychological state of a mammal is disclosed. The device has at least one earpiece with a main body having a body of revolution with an axis of revolution, and an endpiece configured to be inserted into an ear canal. The endpiece has a cylindrical channel intended to receive a body of revolution for detachably mounting the endpiece on the main body, the endpiece being arranged to be movable in rotation about the axis of revolution in order to allow at least one electrode to be oriented toward a zone of the brain of the mammal, and the endpiece having a plurality of electrodes arranged on an outer surface of the endpiece, each electrode being configured to pick up an electrical signal in the ear canal of the mammal.

Abstract: Disclosed systems include a self-contained electroencephalogram (EEG) recording patch comprising a first electrode, a second electrode and wherein the first and second electrodes cooperate to measure a skin-electrode impedance, a substrate containing circuitry for generating an EEG signal from the measured skin-electrode impedance, amplifying the EEG signal, digitizing the EEG signal, and retrievably storing the EGG signal. The patch also comprises a power source and an enclosure that houses the substrate, the power source, and the first and second electrodes in a unitary package.

Abstract: The electrocardiogram measurement apparatus includes: two amplifiers for receiving electrocardiogram signals from a first electrode and a second electrode; one electrode driving unit; a third electrode for receiving an output of the electrode driving unit; an A/D converter connected to an output terminal of each of the two amplifiers and converting analog signals into digital signals; a microcontroller for receiving the digital signals from the A/D converter; and a communication means for transmitting the digital signal, wherein: the microcontroller is supplied with power from a battery; the microcontroller controls the A/D converter and the communication means; and each of the two amplifiers amplifies one electrocardiogram signal so as to simultaneously measure two electrocardiogram signals.

Abstract: A cardiac monitoring and treatment system includes a controller, a first wearable portion, and a second wearable portion separate from the first wearable portion. The first wearable portion includes an elongated strap configured to encircle a thoracic region of a patient, a plurality of ECG sensing electrodes disposed about the elongated strap, one or more receiving ports configured to receive one or more additional components including a treatment electrode and/or an additional sensor, and a plurality of conductive wires configured to couple the plurality of ECG sensing electrodes and the one or more receiving ports with the controller. The second wearable portion is configured to be worn over at least one shoulder of the patient and includes a wearable substrate, one or more treatment electrodes disposed on the wearable substrate, and at least one conductive wire configured to releasably connect the one or more treatment electrodes to the controller.

Abstract: A method includes receiving a plurality of data points including electrophysiological (EP) values measured at respective positions in at least a portion of an organ of a patient. Some of the EP values are classified as outlier values in accordance with a defined criterion. A visual representation of at least the portion of the organ is derived from the plurality of data points. The visual representation represents the EP values with respective colors, and visualizes less than all the outlier values, by performing one or both of (a) identifying outlier values that deviate from respective neighboring EP values by less than a defined deviation, and representing the outlier values using colors that match the neighboring EP values, and (b) setting for the visual representation a mapping, which maps the EP values to the colors and which excludes at least some of the outlier values.

Abstract: Systems and methods are disclosed for visualizing reentrant circuits in the heart via pseudo-activation maps. Techniques disclosed comprise receiving sets of ECG data and respective pacing sites. Each of the sets is generated by pacing heart tissue at a respective site of the pacing sites. Techniques disclosed further comprise computing correlation gradients representative of morphological changes across sets, of the sets of the ECG data, of respective neighboring sites of the pacing sites. Based on the computed correlation gradients, a core zone associated with a reentrant circuit is identified. Then, relative to the identified core zone, one or more pseudo-activation maps are generated.

Abstract: An information processing apparatus includes a selection unit. The selection unit selects whether to calibrate biological information of a user in accordance with designation by the user. When the selection unit selects no calibration in accordance with designation by the user, the biological information is associated with a specific state of the user under a predetermined condition.

Abstract: Methods and systems for improved removal of deep brain stimulation artifacts from electrical measurements of brain activity. In one embodiment, a method is provided that includes: receiving, by a computing device having a processor, waveform data caused by a deep brain stimulation of a patient-specific area of interest; determining, by the computing device, a stimulation period relative to a sampling rate; identifying, by the computing device and based on the waveform data and the stimulation period, a stimulation artifact; subtracting, by the computing device, the identified stimulation artifact from the received waveform data; and generating, in real-time, a filtered waveform data indicating an absence of the stimulation artifact.

Abstract: An electrode includes a core of beryllium copper alloy and a safe metal coating. In some embodiments, the beryllium copper alloy comprises more than three percent beryllium, less than three percent other metals and a remaining percent copper. In some embodiments, an apparatus includes a headband, and a first and second safe metal coated copper-beryllium alloy electrode. The headband is configured to fit snugly to a head of a subject in an orientation from behind a first ear, across a crown of the subject, to a position behind a second ear. The first electrode and second electrode are disposed in the headband to contact a head of the subject at a first position and a different second position, respectively, without gels. In various embodiments, the headband includes a chip to determine an analog signal and transmit data; and, a system includes the headband and a signal analyzing unit.

Abstract: Apparatus for the non-invasive in-vivo determination of changes in tissue, e.g. the myelination, of the optic nerve (ON) in a biological subject, said apparatus comprising: a laser source for generating an excitation laser beam; an optical system including a fundus camera operatively associated with the laser source for use in obtaining a fundus image for illuminating the optic nerve (ON) of a subject with the excitation laser beam; a detector (13) operatively associated with the optical system and configured to detect a Raman spectrum from the optic nerve (ON) and/or surrounding cerebral spinal fluid; and a processor provided with a computer program for comparing the detected Raman spectrum to at least one reference spectrum. The reference spectrum may correspond to the myelination of the optic nerve in a normal, healthy subject, for determining the changes in the myelination of the optic nerve of the subject based on the detecting and comparing steps from the Raman spectrum.

Abstract: One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed.

Abstract: One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed.

Abstract: One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed.

Abstract: One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed.

Abstract: One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed.

Abstract: Methods and apparatus for guiding medical care based on sensor data from the gastrointestinal tract are described utilizing an apparatus which can be used with enteral feeding. Generally, the apparatus includes an elongated body having a length configured for insertion into a stomach and at least one pair of electrodes located along the length of the elongated body and positionable for placement within the stomach. A controller in electrical communication with the at least one pair of electrodes is included and the control may also be configured to measure a conductivity or impedance between the pair of electrodes and to determine a gastric residual volume of the stomach based on the measured conductivity or impedance.

Abstract: Provided is an adhesive tape for collecting skin indigenous microorganisms, the adhesive tape being capable of providing improved collection yields of skin indigenous microorganisms on a skin surface. This adhesive tape is for collecting skin indigenous microorganisms, is used to collect skin indigenous microorganism on a skin surface, and comprises a base material and an adhesive layer provided on at least a portion of a surface of the base material, wherein the adhesive layer contains an adhesive, and the adhesive contains a rubber adhesive. The adhesive tape has an adhesive strength of 10.0 N or more when a 12 mm-wide test piece thereof is pressure-bonded to a Bakelite plate by one reciprocation of a 2 kg roller and then measured for adhesive strength at a pulling speed of 300 mm/min and a pulling angle of 90° according to JIS Z 0237: 2009, and the adhesive tape has a peel strength of 0.

Abstract: The Breast Sense Feeding Monitor provides real-time measurement of breastfeeding metrics including milk volume and infant suck and swallow characteristics over multiple feedings. The wearable design lends itself to versions suitable for both home and in-clinic use.

Abstract: A system and method for conducting a test includes initiating a test script, and providing the script to a patient. Testing hardware is shipped hardware from a provider to the patient, and instructions are provided to the patient for connecting the testing hardware to a mobile computing device. A mobile application is downloaded and installed onto the mobile computing device. The testing hardware is connected to the testing hardware and to the mobile computing device, and the test is conducted using the mobile application operating on the mobile computing device.

Abstract: Systems and methods for providing a preferred fitness state of a use are disclosed. The system includes at least a sensor that detects at least a biological parameter of a user and a fitness state soring module that generates a current user fitness state using machine-learning and the at least a biological parameter. Methods of providing a preferred fitness state of a user include detecting at least a biological parameter of a user, determining by a fitness state sorting module a current user fitness state and determining a user specific recommendation by the fitness state sorting module.

Abstract: Computer-implemented systems and methods for sleep optimization are disclosed. In certain embodiments, the system includes one or more peripheral devices, a network, one or more networked computers, and one or more remote servers. The peripheral devices and/or the networked computers collect one or more types of sleep data, calculate one or more sleep parameters, and transmit said sleep parameters to the one or more remote servers. The remote servers then perform calculations to determine optimal sleep recommendations. The sleep recommendations are then output to one or more networked computers and/or one or more peripheral devices as adjustments to sleep time and sleep duration.

Abstract: A detection appliance and a method detect and evaluate a measuring signal that is indicative of breathing of a sleeping person, in connection with the observation of sleep-related breathing disorders. Instruments also detect signals that are indicative of breathing of a patient. The aim provides solutions that enable a reliable examination in terms of occurrence of sleep-related sleeping disorders, in the usual surroundings of the person concerned. In a first form, a mobile detection appliance is provided with a sensor device for detecting a nasal flow signal indicative of a nasal respiratory gas flow, and/or a respiratory flow signal indicative of an oral respiratory gas flow, in addition to an electronic data processing unit comprising a memory device and processing the signals indicative of temporal course of the nasal and oral respiration. The data processing device is configured to store data indicative of temporal course of the respiratory flow signals.

Abstract: A wearable objective pain measuring device includes a headband configured to be worn by a user on the user's head. The device includes one or more sensors in the headband, including one or more of: a sweep impedance profiling sensor to collect data reflective of activity of corrugator supercilia during a pain session; an electromyography sensor to collect data signals from a brain that reflects pain perception; a photoplethysmogram sensor configured to collect data regarding changes in hear rate and heart rate variability due to pain state; or a galvanic skin response sensor configured to collect data related to changes in sweat gland and skin conductance due to a pain state. The device includes a pain quantification pipeline to objectively quantify pain based on data from the one or more sensors. The device includes an output device configured to output an objective pain quantification based on quantifying pain.

Abstract: A system for preparing a prescription for the use of one or more orthodontal correction devices, such as aligners, which allows for remote interaction and guidance by dental professionals with their patients. The aligner may include a sensor to detect when it is being worn for tracking compliance and determining when the next correction device within the prescription should replace the current correction device. A software application associated with the patient allows them to view and track their progress and to send data to their dental professional, and similarly the dental professional is alerted by the present invention when compliance issues or other issues may arise requiring intervention.

Abstract: Systems, devices and methods are provided for incorporating a medication delivery device into an integrated management system. The integrated management system may be an integrated diabetes management system and may include a glucose monitor, a connected insulin pen, and software. The integrated management system may produce a plurality of reports that may include data related to analyte levels (e.g., glucose levels) and medication delivered (e.g., insulin delivered).