Abstract: Certain embodiments provide an intraocular lens (IOL) including a lens body having a monolithic anterior lens element having an anterior nanostructure assembly formed thereon and a monolithic posterior lens element having a posterior nanostructure assembly formed thereon, and one or more haptics coupled to the lens body.

Abstract: A method of treating a deficient native mitral valve of a heart of a patient includes advancing a steerable, first catheter through the patient’s vasculature, advancing the distal end portion of the first catheter into the heart to position the distal end portion of the first catheter adjacent the native mitral valve, adjusting the curvature of the distal end portion of the first catheter to form a first curve, advancing a distal end portion of a second catheter from a distal end of the first catheter, wherein the distal end portion of the second catheter is pre-shaped to form a second curve when advanced from the first catheter, and deploying a wire from the second catheter such that the wire extends around native leaflets of the native mitral valve.

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves. In one embodiment, a prosthetic heart valve includes a collapsible and expandable annular frame, a leaflet assembly mounted within the annular frame, a first skirt mounted on the frame, and a second skirt mounted on the frame. The frame includes a plurality of rows of cells. The leaflet assembly includes a plurality of leaflets. Adjacent leaflets are connected to each other to form commissures, each of which is connected to a cell of an outflow row of cells of the frame. Inflow end portions of the leaflets are sutured to an outflow end portion of the first skirt along undulating suture line.

Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and a balloon catheter assembly comprising an elongated balloon catheter shaft extending from the handle portion. The balloon catheter shaft includes a proximal end portion coupled to the handle portion and a distal end portion. The balloon catheter assembly further includes a balloon coupled to the distal end portion and configured to mount a prosthetic heart valve in a radially compressed state. A protective cover encapsulates the balloon, the cover defining a cavity shaped to accommodate the balloon.

Abstract: The present disclosure describes a surgical system for an aortic or mitral valve in a heart. The surgical system is configured to pierce, seize, and/or cut a leaflet, and/or facilitate removal of an excised portion of a leaflet.

Abstract: A loading funnel for a prosthetic heart valve includes a proximal connector configured for releasably securing the funnel to a holding tube for a prosthetic heart valve, a distal end for receiving the prosthetic heart valve in an at least partially expanded state, and a passage extending between the distal end and the proximal connector. The passage includes a conical portion that is wider at a distal end and narrower at a proximal end and centered along a cone axis. One or more internal fins each extend from a relatively proximal location in the conical portion to a relatively distal location in the conical portion and protrude toward the cone axis.

Abstract: A composite graft is disclosed, that may replace a segment of the hip labrum during a labral tear reconstruction. The composite graft may include a first sheet that acts as a scaffold and a second sheet that comprises a biologically active component. The first and second sheet are formed in a tubular roll with a spiraled cross section, with alternating layers of the first and second sheet. The composite graft may provide structural integrity for the hip labrum supplemented with growth factors.

Abstract: An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided.

Abstract: An orthopedic implant having a titanium or titanium alloy body with a plurality of surfaces. The orthopedic implant is produced according to a process comprising the steps of: (a) additively building the orthopedic implant; and then (b) mechanically, chemically, or mechanically and chemically eroding one or more surfaces of the orthopedic implant to (i) remove alpha case from, and (ii) impart an osteoinducting roughness including micro-scale structures and nano-scale structures into, the one or more surfaces.

Abstract: A 3D printed bone defect repair scaffold is provided and prepared by steps of: S1, dissolving a gelatin, sodium alginate and a 58S bioglass in water to obtain a solution, and mass-to-volume concentrations of components in the solution being that the gelatin is 16%, the sodium alginate is 6.5% and the 58S bioglass is 8.5%; S2, stirring the solution to obtain 3D printing slurry, and then conducting 3D printing, the 3D printing being performed with a nozzle with an opening diameter of 0.41 mm at a printing speed of 6 mm/s under a pressure of 0.38 Mpa and a temperature of 29° C.; S3, obtaining a semi-finished scaffold after the 3D printing, performing chemical crosslinking of the semi-finished scaffold with a calcium chloride solution for 8-15 min and then immersing in a glutaraldehyde solution for chemical crosslinking for 1.5-2.5 hours, and finally cleaning and lyophilizing.

Abstract: A smart adjustable platform for a bioprinter is described. The adjustable platform comprises: a housing having an upper surface with a support region for providing support for 4D printing of a biomaterial; and at least one stimulator that is mounted within the housing, the at least one stimulator being configured to provide one or more stimuli to the biomaterial during printing and/or after printing for effecting a change in characteristic of the biomaterial including structure and/or morphology, wherein the at least one stimulator comprises a mechanical stimulator and/or an electromagnetic stimulator.

Abstract: Systems and methods are disclosed to manufacture a custom repair or replacement part at the location in which the repair/replacement will be performed. Scans are performed to determine a wear pattern and topology of the location where the replacement part is to be placed and manufacturing instructions are generated to manufacture the repair part using localized manufacturing techniques according to customized parameters to meet functional requirements of the repair/replacement.

Abstract: The present invention discloses a zonal trabecular uni-compartmental tibial plateau containing zirconium-niobium alloy on oxidation layer and preparation method, including following steps: using zirconium niobium alloy powder as raw material, conducting a 3D printing for one-piece molding to obtain an intermediate product of the uni-compartmental tibial plateau, performing hot isostatic pressing and cryogenic oxidation to obtain the uni-compartmental tibial plateau; the lower surface of the semi-tibial plateau support and the surface of the keel plate are both provided with a bone trabeculae; the zonal trabecular uni-compartmental tibial plateau adopts the structure of arranging step distributed bone trabeculaes which can reduce the fretting wear of the interface between the prosthesis and the bone, and reduce the stress shielding effect of the prosthesis on the bone tissue, homogenize the stress of the tibial plateau bone tissue, and improve the initial stability and long-term stability of the uni-compartmen

Abstract: A modular augment cone system and methods of implanting the modular augment cone system. The system includes a main body cone a first cutout in the cone wall, and including a proximal end, a distal end, and a cone wall extending between the proximal and distal ends. A portion of the cone wall proximal to the first cutout includes an attachment feature. A first augment cone is positionable in the first cutout, the first augment cone including an attachment feature configured to mate with the attachment feature of the cone wall to attach the first augment cone into the first cutout. The main body cone can include a second cutout in the cone wall. In such systems, the modular augment cone system can include a second augment cone configured to mate with an attachment feature of the cone wall to attach the second augment cone into the second cutout.

Abstract: A metatarsal hemi-arthroplasty implant may include a convex outer surface overlaying a concave inner surface wherein the convex outer surface is shaped to replace an articular surface of a distal end of a metatarsus. The implant may further include a stem that is configured to be inserted into an intramedullary canal of the metatarsus. The stem may extend from the concave inner surface along a longitudinal axis of the implant, and may have an outward-facing surface disposed at a first angle relative to the longitudinal axis, at least one flute extending along the length, and at least one radial groove formed in the outward-facing surface. The implant may further include a plurality of rib members distributed about the stem member to connect the stem to the inner concave surface. Each of the rib members may have a distally-facing surface disposed at a second angle relative to the longitudinal axis.

Abstract: An interbody spacer for spinal fusion surgery includes a body configured for insertion within an interbody space between two adjacent vertebrae. The body defines at least one fastener-receiving opening for receiving a fastener for securing the body within the interbody space. A blocking member is disposable in the fastener-receiving opening for preventing the fastener from being withdrawn from the fastener-receiving opening once the fastener has been fully inserted into the fastener-receiving opening.

Abstract: Intervertebral spacer assemblies, systems, and methods thereof. A method of insertion includes inserting an intervertebral spacer and plate together using an insertion tool and, upon removal of the insertion tool, the intervertebral spacer and plate are no longer considered connected/coupled and act as separate components.

Abstract: Expandable fusion devices, systems, instruments, and methods thereof. The expandable fusion device is capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. The fusion device may include a body, a first endplate, and a second endplate. A drive screw may be rotated to move the first and second endplates outwardly and into an expanded configuration. Instruments may be provided to ensure the implant is inserted safely and as intended.

Abstract: Improved bone plate systems are described herein. In some instances, a bone plate system can include a base plate, at least one retainer plate, and at least one spacer. The at least one retainer plate is configured to reside on the base plate in a free floating manner and can receive at least one fastener to secure the retainer plate to the at least one spacer, thereby providing a plate system that attaches to a spacer. In other instances, a bone plate system can include a base plate having one or more push plates that can engage at least one spacer.

Abstract: A minimally invasive intervertebral implant includes a circuitous body defining a luminal axis extending longitudinally therethrough. The circuitous body includes proximal and distal ends oppositely disposed along a lateral axis of the circuitous body. Each of the proximal and distal ends includes an aperture disposed therethrough such that the circuitous body includes a first configuration wherein the proximal and distal ends are at a maximum separation and a second configuration wherein the proximal and distal ends are closer together than in the first configuration.

Abstract: Disclosed herein are joint implants and methods for tracking joint implant performance. A joint implant includes a first implant coupled to a first bone of a joint and a second implant coupled to a second bone of the joint. The second implant includes at least one of a first sensor configured to measure a first type of data, and a processor operatively coupled to the at least one of the first sensor. The process outputs the first type of data to a network to be compared with data received from other joint implants. One of the joint or the implant is determined to be in a first state based on a comparison of the first type of data to a set of predetermined values formed based on the data received from the other joint implants. The predetermined values are adapted to change with the addition of new data.

Abstract: Disclosed herein are systems and methods for providing secure authentication and connection between an implant and a remote monitoring platform for tracking implant performance. A joint implant according to the present disclosure can include a first implant coupled to a first bone of a joint, a second implant coupled to a second bone of the joint, a first communication module, and a memory to store authentication information. The first communication module can be configured to wirelessly transfer the authentication information to a communication module of an external device when the external device is placed adjacent the joint implant. The first communication module can be an NFC communication module configured to transfer the authentication information to the communication module of the external device via NFC.

Abstract: A system is disclosed herein for providing a kinetic assessment and preparation of a prosthetic joint comprising one or more prosthetic components. The system comprises a prosthetic component including sensors and circuitry configured to measure load, position of load on a curved surface, joint stability, range of motion, and impingement. In one embodiment, the system is for a cup and ball joint of a musculoskeletal system. The system further includes a computer having a display configured to graphical display quantitative measurement data to support rapid assimilation of the information. The kinetic assessment measures joint alignment under loading that will be similar to that of a final joint installation. The kinetic assessment can use trial or permanent prosthetic components. Furthermore, adjustments can be made to the applied load magnitude, position of load, and joint alignment by various means to fine-tune an installation.

Abstract: Disclosed herein are joint implants and methods for tracking joint implant performance. A joint implant according to the present disclosure can include a first implant coupled to a first bone of a joint; a second implant coupled to a second bone of the joint; an insert coupled to the first and second implants; an acoustic exciter configured to emit a vibration signal; a sensor to measure the vibration signal of the first implant, the second implant, and the insert; and a processor operatively coupled to the sensor, the processor configured to output a vibration signature to an external source.

Abstract: The invention relates to a prosthetic foot with a foot part 2 and a lower leg part 4 that is connected to the foot part 2 such that it can be pivoted about a pivot axis 6 and that can be locked in various pivot angles relative to the foot part 2, the connection between the lower leg part 4 and the foot part 2 having a clearance in the pivot direction when the foot part 2 is locked on the lower leg part 4, the prosthetic foot having at least one friction element 14 arranged between the foot part 2 and the lower leg part 4 and applying a frictional torque that counteracts a pivoting of the foot part 2 relative to the lower leg part 4 when the foot part 2 is locked relative to the lower leg part 4.

Abstract: The present disclosure relates to an orthotic (or brace) and/or prosthetic ankle joint and associated methods adapted to enable adjustment of a talus section or ankle portion or brace with respect to a tibial section of the orthotic (or brace) and/or prosthetic ankle joint. The talus section or ankle portion of the orthotic (or brace) and/or prosthetic ankle joint is movably coupled to the tibial section with the alignment between the talus section and tibial section being adjustable between various positions by disengagement or engagement of a lock of an adjustment mechanism. As the lock is disengaged, the talus section is enabled to pivot with respect to the tibial section in at least one direction as the user moves along a slope.

Abstract: An implant (6, 18) for influencing the flow of blood in the area of bifurcation aneurysms with the implant (6, 18) having a first (1, 14) and a second tubular braided section (2, 15) each having an opening (4, 5, 16, 17) in the wall, wherein the openings (4, 5, 16, 17) in the walls being produced in such a way that the wires (3) forming the braided sections (1, 2, 14, 15) are radially displaced at the positions of the openings (4, 5, 16, 17), and the first braided section (1, 14) is guided through the opening (5, 17) in the wall of the second braided section (2, 15) such that the opening (4, 16) in the wall of the first braided section (1, 14) points to the opening (5, 17) in the wall of the second braided section (2, 15).

Abstract: A clot mobilizer device for extraction of an occlusion from a blood vessel is provided, which comprises a working portion including a plurality of crowns of cells. Each cell comprises an open area bordered by struts. A distal end of each cell in a first crown is contiguous with a proximal end of a corresponding cell in a third crown, and a distal end of each cell in a second crown is contiguous with a proximal end of a corresponding cell in a fourth crown. The second crown is disposed distal to the first crown and proximal to the third crown, and the fourth crown is disposed distal to the third crown. The plurality of crowns of cells define a tubular-shaped section forming a cylindrically closed structure. The clot mobilizer also comprises a tapered portion extending proximally from the proximal end of the working portion and comprising a plurality of struts.

Abstract: A medical stent having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, may include a plurality of first filaments each extending in a first helical path around the central longitudinal axis in a first direction and a plurality of second filaments each extending in a second helical path around the central longitudinal axis in a second direction. The plurality of first filaments may be interwoven with the plurality of second filaments. The first helical path of at least one of the plurality of first filaments may include a circumferential offset disposed between the first end and the second end.

Abstract: An example stent delivery system is disclosed. The example stent delivery system includes an outer shaft having a distal end region, an inner surface and a lumen extending therein. The delivery system also includes an inner shaft extending within the outer shaft lumen, the inner shaft having a stent receiving region disposed along a distal end region thereof. Additionally, the delivery system includes a stent disposed along the stent receiving region and a braided member positioned radially outward from an outer surface of the stent and radially inward from the inner surface of the outer shaft, the braided member being attached to an outer surface of the inner member proximal of the stent. Additionally, the delivery system includes a plurality of tether members coupled to the braided member, wherein longitudinal retraction of the outer shaft relative to the inner shaft exposes the stent from the braided member.

Abstract: A method for shortening a duodenum of a subject, the method including: manipulating a first surface of the duodenum wall such that a first portion of the first surface of the duodenum wall is layered onto a second portion of the first surface of the duodenum wall, thereby creating at least one fold in the first surface of the duodenum wall, and securing, utilizing at least one implant, the position of the at least one fold in relation to a surrounding surface of the duodenum wall, thereby shortening the duodenum of the subject.

Abstract: A calcaneal inversion-inducing orthotic sleeve and method of wearing helps treat and relieve pressure off the calcaneal. The orthotic sleeve comprises a compression sock that fits over a substantial portion of the foot. The compression sock defines a toe opening, a heel opening, and an ankle opening. An ankle rim extends over the ankles for enhanced fit. The orthotic sleeve also includes a calcaneal inversion strap having a first end and a second end with hook and loop fasteners for attachment. The calcaneal inversion strap is pulled from the first end and wrapped around the base of the calcaneus (heel) from lateral to medial general. The first and second ends are attached. The calcaneal inversion strap induces a slight inversion of the ankle; whereby the orthotic reverses the anatomical abnormality from excess pronation and calcaneal eversion caused by pes planus and other etiologies, while allowing the wearer to heal and perform normal functional activities.

Abstract: A stirrup footplate made up of a plastic main body having a predetermined thickness and a generally elongated configuration extending along a main axis. The main body has a toe end with a generally extending below a forefoot of the user when bonded to an AFO, and a heel end with a cross-like configuration, wherein the cross-like configuration has a pair of lateral extensions extending substantially perpendicularly from the main axis. The lateral extensions sized so that an end portion of each lateral extension will be formable in a manner to extend up an opposite side of the thermoplastic AFO when bonded thereto. The cross-like configuration further having a heel extension which extends along the main axis and can extend at least partially up a heel side of the AFO when bonded thereto. The plastic main body is form of a material having a predetermined stiffness which is stiffer than the thermoplastic AFO which will provide support to the user's heel and foot bed.

Abstract: An ankle foot orthosis (AFO) for use on the lower limb of a person involves a shell having a phalangeal section, a heel section, and an upright portion coupled to the heel section dimensioned to extend, substantially perpendicular to the heel section, from the heel section, and wherein at least the phalangeal section is flexible in a plantar flexation direction; and wherein the upright portion is substantially rigid so as to inhibit plantar flexion of the person's foot.

Abstract: An anterior bracing system deployed as part of an orthopedic brace is described. The anterior bracing system features an anterior panel and a plurality of telescopic lateral panels. The anterior panel includes a plurality of rotatable locking members, each disposed on an opposing side of the anterior panel. The telescopic lateral panels are configured to extend in a lateral direction or retract in a medial direction. The plurality of rotatable locking members are configured to rotate between an open position and a closed position. When the locking members are placed in the open position, the telescopic lateral panels are configured to extend or retract. When the locking members are placed the closed position, the telescopic lateral panels are locked in a current position.

Abstract: A non-surgical corrective apparatus for a deformed external ear is described. The corrective apparatus may be worn externally to correct a deformity or malformation on the external ear through molding over a period of time. In one aspect, the corrective apparatus includes a corrective component configured for contacting a target surface of the external ear and maintaining a desired shape to reshape the deformity; and an attachment element configured for placement around a helix of the ear for remodeling the outer portion of the helix and securing the corrective component against the target surface. The attachment element is strong enough to maintain the corrective component in place during the time period of use and sufficiently atraumatic to avoid causing any harm or further deformities to the patient's ear during use or removal.

Abstract: A bacteria formulation includes bacteria including odor neutralizing bacteria configured to oxidize hydrogen sulfide and/or methyl mercaptan and one or more compounds for supporting viability of the bacteria.

Abstract: Abase plate for an ostomy appliance including a removable protection element provided on a proximal adhesive surface of the base plate wherein an uptake portion is provided on the removable protection element and is adapted to take up stomal effluents. Further disclosed are methods of preventing stomal effluents from the stoma from contaminating the adhesive material of the base plate during application of the base plate to the skin surface around the stoma of the user, as well as a kit of parts and an accessory for a base plate of an ostomy appliance.

Abstract: A sensing accessory for detecting leakage in an ostomy device includes a sensor region. The sensor region has a plurality of electrodes providing a plurality of sensors arranged around a stoma-receiving opening. Each of the plurality of electrodes is arranged at a different radial distance from the stoma-receiving opening. A connector is connected at a first end to the plurality of electrodes and extends to a second terminal end that is configured for electrical connection to an external monitor device.

Abstract: An ostomy appliance comprising a main body portion comprising an inner wall and an outer wall of flexible sheet material joined together to define a cavity for containing a stomal output; the inner wall comprising an inlet for receiving the stomal output into the cavity; the ostomy appliance further comprising an outer comfort layer overlying at least a portion of the outer wall; wherein the outer comfort layer comprise a first part and a second part which are joined to the outer wall so that the first part partially overlaps the second part in an overlap region, wherein the first part and the second part are separable from each other in the overlap region to form a window opening for viewing the cavity; wherein the overlap region is angled obliquely to a horizontal direction when the ostomy appliance is orientated as it would be in use.

Abstract: A menses collecting apparatus includes a basin and a closure. The basin may transition between a collapsed or folded state prior to insertion by a user and an expanded or unfolded state after insertion by the user. The menses collecting apparatus may be collapsible/closed radially prior to insertion by the user, and may collect menses in the expanded state after insertion by the user. The closure may also transition between an open configuration and a closed configuration. The closure may be collapsible/folded when transitioning between the open configuration and the closed configuration. When the basin is in the expanded state, the closure may also be in an open configuration or the closed configuration. The menses collecting apparatus may employ a tension-based mechanism to transition between the different basin states and closure configurations. The menses collecting apparatus may be configurable to fit within an applicator to assist in the insertion of the menses collecting apparatus.

Abstract: A reusable menstrual discharge collection device is described comprising: dual durometer article that forms a menstrual discharge disc-shaped collection device with a half spherical dome catch where the half spherical dome catch includes a continuous circumferential top and bottom portion, and wherein the continuous top portion is attached to a continuous uniform flexible hinge that is placed along an entire circumferential uniform upper portion of the half spherical dome catch and wherein the hinge also forms a base for and is connected to a 360-degree continuous uniform circumferential rim section such that the hinge allows the half spherical dome catch to be in both an inverted use position/configuration that allows movement of the catch toward the rim section allowing for adjustability to fit multiple cervix physiologies and the elongated configuration allows for ease of manufacturing and cleaning.

Abstract: An intraoral device having a main body to be attached to maxillary teeth, the main body including a first region, a second region, and a third region. Mandibular anterior teeth are in contact with the first region. The mandibular anterior teeth in contact with the first region are moved toward the third region while being kept in contact with the second region, which causes the mandible to move anteriorly and superiorly.

Abstract: Implantable tube valve for implanting in a human vessel, comprising a tube, having an inner and outer tube wall extending between two axial tube ends and comprising a valve member, connected to a pivot shaft supported by the tube, with the valve member pivotable between an open position and a closed position and comprising an actuator mechanism, mounted on the outer tube wall and comprising a pivot member, arranged for driving the pivot shaft from the outer tube wall by an actuation force from the actuator mechanism and comprising at least one biasing element, connected to the pivot member and arranged for preloading the pivot member to bistably bias the valve member towards the open or closed position, wherein the biasing element comprises at least two bow-shaped rods that are interconnected at both ends in a mirrored fashion.

Abstract: A medical heating device for heating a person that includes an electronic control unit that is configured as a recyclable module; a flexible heating blanket that is configured to at least partially shield the person from their environment, the flexible heating blanket can be separated from the control unit without destruction, and the flexible heating blanket is configured as a disposable item to permit regular replacement; a heating layer with a carrier layer of a polymeric material and a resistance layer of an electrically conductive material, the heating layer is configured to convert electrical energy into heat, and a plurality of temperature sensors to control the heating layer.

Abstract: An eye compress assembly includes two thermally adjustable heating and cooling device and a bridge connecting the two devices is provided. The thermally adjustable device is configured to apply thermal treatment against the eye region. Within the thermally adjustable heating and cooling device the thermoelectric element is powered by a battery. A power input port is provided in the bridge to connect into a power supply in order to recharge the battery.

Abstract: Disclosed is a system (100) for securing a patient, intended to interact with a robotic platform equipped with a surgical instrument (30) suitable for eye surgery, the system comprising: —at least one ocular sensor (110) capable of detecting movement of an eye (10) of the patient and/or at least one cephalic sensor (120) capable of detecting a movement of the head (20) of the patient; and—a data processing means (130) for receiving data from the ocular sensor (110) and/or the cephalic sensor (120), processing the data in order to determine a level of risk for the patient on the basis of a predetermined criterion, then automatically sending a command for securing the patient to the robotic platform, the command being dependent on the previously determined risk level.

Abstract: A spray device for delivering a liquid spray, having a spray length, through air to a target, in particular an eye, comprises a container for holding a liquid, means for pressurizing a quantity of said liquid to an elevated operating pressure, and comprises a nozzle member that comprises a nozzle plate with a plurality of nozzle orifices of substantially identical size, extending through said nozzle plate and communicating with said means to receive a quantity of pressurized liquid at said operating pressure. Said nozzle orifices discharge said liquid spray at an outlet surface of said nozzle member member over said spray length Their substantially identical size is between lower and upper limits (Dmin), (Dmax), wherein said lower limit is approximately: D ? min ? 1 / 10 ? L ? ? ? ? P / ? , wherein said upper limit is approximately: D max ? 1 / 10 ? 2 ? L ? ? ? ? P / ? . ??18 ?/?, ?=1,8.

Abstract: Systems, devices, and methods for replacing an eyedropper tip on an eyedropper bottle with a replacement eyedropper tip. Such a system may include, without limitation, a removal tool, an application tool, and a replacement eyedropper tip. The removal tool may be used to remove a preexisting eyedropper tip on an eyedropper bottle, and the application tool may be used to apply the replacement eyedropper tip to the eyedropper bottle. In some embodiments, the replacement eyedropper tip and the application tool may be formed as a single unit or effectively be the same component.