Patents Issued in September 28, 2023
  • Publication number: 20230302415
    Abstract: Described herein is a membrane for use in membrane distillation, comprising a porous polymer matrix and functionalized graphene or graphene oxide, the graphene or graphene oxide being functionalized with a polyhedral oligomeric silsesquioxane. The present membrane have improved separation performance.
    Type: Application
    Filed: August 16, 2021
    Publication date: September 28, 2023
    Inventor: Sebastian LEAPER
  • Publication number: 20230302416
    Abstract: Embodiments provide a filter with a generally rectangular, non-cylindrical profile. The filter may have multiple pleat packs positioned between pleat covers that define regions and flow channels in a cavity of the filter body. The pleat covers have openings that allow a fluid to flow through the multiple pleat packs via parallel flows or series flows. End caps bonded to the body define flow passages for directing the fluid from an inlet to an outlet via the pleat packs for series or parallel filtration. The pleat packs may be made of the same or different materials and may be configured with the same or different heights based on flow requirements. A cage or a separator may be positioned between the pleat packs. The pleat packs may be made of a continuous pleated membrane with bridges defining a space between the pleat packs to accommodate the cage or separator.
    Type: Application
    Filed: May 18, 2023
    Publication date: September 28, 2023
    Inventors: Kalyan MADHAVARAM, Bryan Carl COCHRAN, John Paul PUGLIA, J. Karl NIERMEYER, Krishna KAMATH, Christopher Paul BARCK, Yoshikimi Douglas HISANO
  • Publication number: 20230302417
    Abstract: A method includes obtaining a cartridge having a first fluid within an interior of the cartridge, where the cartridge includes a valve; obtaining a container having a second fluid within an interior of the container; obtaining a pressurizer; installing the cartridge within the pressurizer; installing the pressurizer within a container opening at a top end of the container; and opening the valve in the cartridge, to flow the first fluid within the interior of the cartridge through a first flow path in the valve, and a second flow path in the pressurizer into the second fluid in the container.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 28, 2023
    Inventors: Mark Wiggins, John Thorp, JonPaul Turner
  • Publication number: 20230302418
    Abstract: The invention relates to a carbonation apparatus (10), in particular for the introduction of carbon dioxide to liquid, having a gas outlet which is configured to be introduced into a container (7) which can be filled with liquid, a gas connector which is fluidically connected to the gas outlet via a controllable valve (4), a control device (5) which is configured to control the valve (4), comprising, furthermore: a fixture (1) with a weight determining device for determining a weight of a gas cylinder (3) which is received in the fixture (1) and is connected to the gas connector.
    Type: Application
    Filed: March 23, 2023
    Publication date: September 28, 2023
    Applicant: Aquis Systems AG
    Inventor: Ingolf Gröning
  • Publication number: 20230302419
    Abstract: The contacting device for countercurrent contacting of fluid streams and having a first pair of intersecting grids of spaced-apart and parallel deflector blades and a second pair of intersecting grids of spaced-apart and parallel deflector blades. The deflector blades in each one of the grids are interleaved with the deflector blades in the paired intersecting grid and may have uncut side portions that join them together along a transverse strip where the deflector blades cross each other or adjacent opposed ends of the deflector blades and cut side portions that extend from the uncut side portions to the ends of the deflector blades. At least some of the deflector blades have directional tabs and associated openings to allow portions of the fluid streams to pass through the deflector blades to facilitate mixing of the fluid streams.
    Type: Application
    Filed: May 29, 2023
    Publication date: September 28, 2023
    Inventors: Izak Nieuwoudt, Sergio ESCOBAR
  • Publication number: 20230302420
    Abstract: Parallel uses of microfluidic methods and devices for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid are described. In some aspects, the present invention relates generally to flow-focusing-type technology, and also to microfluidics, and more particularly parallel use of microfluidic systems arranged to control a dispersed phase within a dispersant, and the size, and size distribution, of a dispersed phase in a multi-phase fluid system, and systems for delivery of fluid components to multiple such devices.
    Type: Application
    Filed: November 1, 2022
    Publication date: September 28, 2023
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Mark Romanowsky, Adam R. Abate
  • Publication number: 20230302421
    Abstract: Methods of heating a reactor system by providing electrical energy are described. A reactor system comprising at least one reactor tube having a catalyst disposed therein and comprises at least one electrically conductive surface is heated by providing electrical energy to the at least one electrically conductive surface on the reactor tube and adjusting a current level of the electrical energy provided to the at least one electrically conductive surface to control the temperature of the reactor tube and the catalyst disposed therein. The reactor tube may be electrically isolated from other electrically conductive components of the reactor system.
    Type: Application
    Filed: May 3, 2023
    Publication date: September 28, 2023
    Inventors: Lanyon Carr, Gregoire Quere
  • Publication number: 20230302422
    Abstract: A sequencing kit includes a plurality of particles and a flow cell. The plurality of particles includes a primer set attached to a surface of each of the plurality of particles; and a flow cell surface attachment mechanism attached to the surface of each of the plurality of particles. The flow cell surface attachment mechanism is selected from the group consisting of a capture primer, an alkene, an alkyne, biotin, and a charged polymer. The flow cell includes a plurality of chemical pads that are spatially separated from one another on a substantially flat substrate surface, each of the chemical pads including chemistry to attach to the surface attachment mechanism.
    Type: Application
    Filed: March 21, 2023
    Publication date: September 28, 2023
    Inventors: Zhong Mei, Adithya Ramanitharapandian, Zhonghuan Luo, Hui Han
  • Publication number: 20230302423
    Abstract: Methods for designing scaffolded RNA nanostructures of desired shape are described. In some forms, the methods design nucleic acid “staple” sequences that hybridize to a user-defined RNA scaffold and fold it into the desired shape based on A-form helical nucleic acid geometry. In some forms, the methods implement asymmetry in nucleotide positions across two helices of an edge to account for A-form nucleic acid geometry. In preferred forms, crossover asymmetry is implemented in the staples. In other forms, crossover asymmetry is implemented in the RNA scaffold. In other forms, the methods do not introduce crossover asymmetry. Scaffolded RNA nanostructures produced according to the methods including messenger RNAs, replicating RNAs, functional RNAs and other RNA species within the scaffold, staples, or both scaffold and staples are provided. Modified nanostructures including chemically modified nucleotides are also described.
    Type: Application
    Filed: March 28, 2023
    Publication date: September 28, 2023
    Inventors: Mark Bathe, Tyson Shepherd, Molly Frances Parsons
  • Publication number: 20230302424
    Abstract: An extruder and valve system comprises a conduit for conveying a biomass stream using a plurality of injector assemblies to provide water or other fluids and/or steam for pretreatment. Each injector in the assembly is connected to a corresponding port in the extruder. The ports can be positioned at discrete locations of the extruder or beyond to deliver the appropriate amount of fluid or steam for the processing of biomass or other materials.
    Type: Application
    Filed: March 29, 2023
    Publication date: September 28, 2023
    Inventors: Sharon SAMJITSINGH, Scott TUDMAN
  • Publication number: 20230302425
    Abstract: A reactor and method for the conversion of hydrocarbon gases utilizes a reactor (12, 312, 412, 512, 612) having a unique feed assembly with an original vortex combustion chamber (40, 340, 436, 536, 636), a diverging conduit (48, 348, 448, 548, 648), and a cylindrical reactor chamber (40, 340, 436, 536, 636). This design creates a compact reaction zone and an inwardly swirling fluid flow pattern of the feed gases to form a swirling gas mixture that passes through a diverging conduit (48, 348, 448, 548, 648). The feed streams can be introduced into the reactor (12, 312, 412, 512, 612) at any angle (radial, axial, or something between, or a combination of the above forms) with swirling flow components. The feed streams comprise preheated steam and hydrocarbons for cracking. This system provides conditions suitable for efficient cracking of hydrocarbons, such as ethane, to form olefins.
    Type: Application
    Filed: July 6, 2021
    Publication date: September 28, 2023
    Inventors: Sreekanth Pannala, Arno Johannes Maria Oprins, Lei Chen
  • Publication number: 20230302426
    Abstract: Disclosed is a reactor for carrying out a chemical reaction and a corresponding method. The reactor includes a vessel and one or more reaction tubes where a number of tube sections of the reaction tubes run between first second regions in the reactor vessel, and where the tube sections in the first region for the electrical heating of the tube sections can be electrically connected to the phase connections of a polyphase AC power source. Tube sections in the second region are electrically and conductively connected to one another as a whole by means of a single rigid connecting element, or in groups by means of a plurality of rigid connecting elements which are integrally connected to the reaction tubes and are arranged inside the reactor vessel. A corresponding method is also the subject-matter of the present invention.
    Type: Application
    Filed: February 9, 2021
    Publication date: September 28, 2023
    Inventors: Mathieu Zellhuber, Martin Hofstatter, Heinz Posselt, Christian Lang, Clara Delhomme-Neudecker
  • Publication number: 20230302427
    Abstract: A silicon carbide flow reactor fluidic module comprises a monolithic closed-porosity silicon carbide body and a tortuous fluid passage extending through the silicon carbide body, the tortuous fluid passage lying within two or more layers with the silicon carbide body, the tortuous passage having an interior surface, the interior surface having a surface roughness of less than 10 ?m Ra. A method of forming the fluidic module is also disclosed.
    Type: Application
    Filed: June 24, 2021
    Publication date: September 28, 2023
    Inventors: Alexander Lee Cuno, Howen Lim, James Scott Sutherland, Oscar Walter Wheeler
  • Publication number: 20230302428
    Abstract: An inorganic material in a form of open-porosity particles, each of the particles comprising a lead vanadate or phosphovanadate of formula Pb3-xXx(VO4)2-2y(PO4)2y,wherein x = 0 or x > 0 but ? 0.33; y = 0 or y > 0 but < 1;X = Ba2+, Ca2+, Sr2+ or Cd2+; and metallic lead or a lead salt. A method for preparing the material, a method for capturing iodine present in a gaseous effluent as well as a method for conditioning iodine present in a gaseous effluent in a form of an iodoapatite.
    Type: Application
    Filed: December 15, 2022
    Publication date: September 28, 2023
    Inventors: Lionel Campayo, Raphaël Penelope
  • Publication number: 20230302429
    Abstract: An adsorbent comprising at least two types of covalently bound antigens having the ability to bind at least one component present in a blood flow or blood plasma flow passing through said adsorbent is disclosed, as well as a column containing said adsorbent, a kit containing said column in a sealed plastic bag, a method for the production of said kit, a method for reduction or elimination of undesired blood group specific antibodies or autoimmune antibodies in connection with autoimmune diseases, a method for treatment of myasthenia gravis, and a method for treatment of rheumatoid arthritis.
    Type: Application
    Filed: October 29, 2020
    Publication date: September 28, 2023
    Applicant: GLYCOPROBE AB
    Inventor: Kurt NILSSON
  • Publication number: 20230302430
    Abstract: The present disclosure provides an adsorbent which is produced using a low environmental load material as a raw material and adsorbs selenious acid selectively and efficiently. A selenious acid adsorbent according to the present disclosure includes a cellulose derivative (I) having a repeating unit represented by Formula (I).
    Type: Application
    Filed: August 11, 2020
    Publication date: September 28, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY, DAICEL CORPORATION
    Inventors: Hiroshi HASEGAWA, Keisuke NAKAKUBO, Koki YUNOSHITA, Asami MASHIO, Katsuhiro MAEDA, Tsuyoshi TANIGUCHI, Tatsuya NISHIMURA, Yoko MITSUHASHI, Masaru ENDO, Takashi ARAI
  • Publication number: 20230302431
    Abstract: The present invention relates to an adsorbent including: an inorganic porous body; and an amine compound, in the inorganic porous body has an oil absorption value of 230 ml/100 g or more, and a peak diameter of a pore size, which is obtained based on a nitrogen adsorption method, of 20 nm or more and 100 nm or less. The present invention relates to an adsorbent including: an inorganic porous body; and an amine compound, in which the inorganic porous body has a pore volume of 1.2 cm3/g or more and 3.5 cm3/g or less, and a peak diameter of a pore size, which is obtained based on a nitrogen adsorption method, of 20 nm or more and 100 nm or less.
    Type: Application
    Filed: May 12, 2023
    Publication date: September 28, 2023
    Applicants: AGC Inc., AGC SI-TECH CO., LTD.
    Inventors: Eisuke MUROTANI, Ryohei KOGUCHI, Taku YAMADA, Katsumasa NAKAHARA, Hajime KATAYAMA, Masaki INOUE
  • Publication number: 20230302432
    Abstract: A porous shaped catalyst support body comprising at least 85% by weight of alpha-alumina, wherein the support has a total pore volume in the range from 0.5 to 2.0 mL/g as determined by mercury porosimetry, and a pore structure characterized by a geometric tortuosity ? in the range from 1.0 to 2.0; and an effective diffusion parameter ? in the range from 0.060 to 1.0; wherein geometric tortuosity ? and effective diffusion parameter ? are determined by image analysis algorithms from computer-assisted 3D reconstructions of focused ion beam scanning electron microscope analyses. The structure of the support has a high total pore volume, such that impregnation with a large amount of silver is possible, while the surface area is kept sufficiently high in order to assure optimal dispersion of the catalytically active species, especially metal species. The support has a pore structure that leads to a maximum rate of mass transfer within the support.
    Type: Application
    Filed: June 25, 2021
    Publication date: September 28, 2023
    Inventors: Sung Yeun CHOI, Andrey KARPOV, Christian WALSDORFF, Patrick HUBACH, Hubert WAINDOK, Bernd HINRICHSEN, Gonzalo PRIETO GONZALEZ, Tania RODENAS TORRALBA, Karl C. KHARAS
  • Publication number: 20230302433
    Abstract: Metal oxide nanoarrays, such as titanium oxide nanoarrays, having a platinum group metal dispersed thereon and methods of making such nanoarrays are described. The platinum group metal can be dispersed on the metal oxide nanoarray as single atoms. The nanoarrays can be used to catalyze oxidation of combustion exhaust.
    Type: Application
    Filed: May 4, 2023
    Publication date: September 28, 2023
    Inventors: Pu-Xian Gao, Son Hoang
  • Publication number: 20230302434
    Abstract: Provided is an exhaust gas purification catalyst that includes a base material containing a silicon-silicon carbide composite material and a catalyst layer containing a barium component and that has excellent high-temperature durability of oxygen storage capacity. The exhaust gas purification catalyst disclosed here includes a base material and a catalyst layer in contact with the base material. The base material contains a silicon-silicon carbide composite material. The catalyst layer contains a platinum-group catalyst, a barium component, and an oxygen storage material. The barium component is one material selected from the group consisting of barium and a barium compound. The barium component is present on at least a surface of the oxygen storage material. The barium component has an average particle size of 100 nm or more and 350 nm or less.
    Type: Application
    Filed: July 19, 2021
    Publication date: September 28, 2023
    Inventors: Tatsuya Ohashi, Kohei Takasaki, Yu Onohara, Keiichi Narita
  • Publication number: 20230302435
    Abstract: A catalyst for purification of exhaust gas in which Pd-based nanoparticles and ceria nanoparticles represented by CeO2-x, (0?x<0.5) are supported on a composite metal oxide support containing alumina, ceria, and zirconia, wherein a molar ratio (Ce/Pd) of Ce and Pd supported on the support is 1 to 8, a proximity ? between Pd and Ce is 0.15 to 0.50, wherein the proximity ? is determined, based on Pd and Ce distribution maps in an element mapping image of energy dispersive X-ray analysis, by the following formula (1) ? = ? j = 0 N - 1 ? ? i = 0 M - 1 ? ( ( I ? ( i , j ) - I ave ) ? ( T ? ( i , j ) - T ave ) ) ? j = 0 N - 1 ? ? i = 0 M - 1 ? ( I ? ( i , j ) - I ave ) 2 - ? j = 0 N - 1 ? ? i = 0 M - 1 ? ( T ? ( i , j ) - T ave ) 2 , ( 1 ) and a Pd dispersity after a heat-resistance test is 0.
    Type: Application
    Filed: November 2, 2022
    Publication date: September 28, 2023
    Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Naoki KUMATANI, Akira MORIKAWA, Masaoki IWASAKI, Miho HATANAKA, Taizo YOSHINAGA, Masahide MIURA, Takahiro HAYASHI
  • Publication number: 20230302436
    Abstract: Methods and compositions for the removal of metal sulfides from spent catalysts in reactor vessels and associated equipment are described herein. Using the methods described herein, metal sulfides of a spent catalysts are converted to metal oxides and gaseous and liquid by-products when reacted with a formulation having one or more oxidizing agents. Also, using the methods described herein, metal sulfides and sulfides in the process equipment are oxidized, eliminating the potential formation of polythionic and thionic acids protecting materials from polythionic stress corrosion cracking. Also, using the methods described herein, halides (including chloride) and halide containing compounds and salts in the process equipment are removed, eliminating the potential formation of halide acids and further neutralized via pH buffering, and protecting materials from halide stress corrosion cracking.
    Type: Application
    Filed: July 28, 2021
    Publication date: September 28, 2023
    Inventors: James Esteban, Sean Sears, Trey Schuenemann
  • Publication number: 20230302437
    Abstract: Compositions and methods for hydrogen production are disclosed.
    Type: Application
    Filed: October 19, 2022
    Publication date: September 28, 2023
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Jennifer Timm, Paul G. Falkowski, Vikas Nanda, Alexei M. Tyryshkin, Saroj Poudel, Joshua A. Mancini, Douglas H. Pike
  • Publication number: 20230302438
    Abstract: According to a technique disclosed herein, provided is an exhaust gas purification catalyst, which both suppresses OSC when using a new vehicle and maintains OSC during life cycles. The exhaust gas purification catalyst disclosed herein is an exhaust gas purification catalyst includes a substrate, and a catalyst coated layer formed on the surface of the substrate, wherein the catalyst coated layer contains an OSC material having an oxygen storage capacity. The catalyst coated layer includes a Rh layer mainly containing Rh as a catalyst metal, and a Pd/Pt layer mainly containing Pd and/or Pt as a catalyst metal. At least a portion of the Pd/Pt layer in the catalyst coated layer contains, as the OSC material, a low specific surface area OSC material, including a ceria-zirconia composite oxide and having a specific surface area of 40 m2/g or more and 60 m2/g or less.
    Type: Application
    Filed: June 4, 2021
    Publication date: September 28, 2023
    Inventors: Ryota Onoe, Takahiro Noguchi, Tatsuya Ohashi, Kohei Takasaki
  • Publication number: 20230302439
    Abstract: A method for preparing a copper-containing catalyst is described comprising the steps of: (a) combining an acidic copper-containing solution with a basic precipitant solution in a first precipitation step to form a first precipitate, (b) combining an alkali metal aluminate solution with an acidic solution in a second precipitation step to form a second precipitate, (c) contacting the first and second precipitates together in a further precipitate mixing step to form a catalyst precursor, and (d) washing, drying and calcining the catalyst precursor to form the copper-containing catalyst, wherein at least 70% by weight of the copper in the catalyst is present in the first precipitate and a silica precursor is included in the first precipitation step, the second precipitation step or the precipitate mixing step, to provide a catalyst with a silica content, expressed as SiO2, in the range of 0.1 to 5.0 wt %.
    Type: Application
    Filed: September 6, 2021
    Publication date: September 28, 2023
    Inventors: Youxin CUI, Monica GARCIA, Pauline Elizabeth GLEN, Norman MACLEOD, Michael Thomas NICHOLSON, Simone ROLOFF-STANDRING, Kaamila UN DIN
  • Publication number: 20230302440
    Abstract: A metal ratio inspection method for inspecting a metal ratio of a thermally sprayed composite material containing at least one metal and at least one ceramic, the method includes: an imaging step (step S11) of imaging the thermally sprayed composite material while irradiating the thermally sprayed composite material with imaging light; and an estimating step (step S12) of estimating a metal ratio of the thermally sprayed composite material based on a luminance distribution of the image of the thermally sprayed composite material obtained in the imaging step.
    Type: Application
    Filed: March 16, 2023
    Publication date: September 28, 2023
    Applicant: NGK Insulators, Ltd.
    Inventors: Rina YOKOI, Takashi NORO, Takamichi SATO
  • Publication number: 20230302441
    Abstract: The invention relates to the development of quaterphenylene polymer derivatives with synthetic methodologies towards controllable and integer degree of functionalization on the quaterphenylene polymer backbone with specific number of side phenyl groups and monovalent hydrocarbon groups terminated by a functional group consisting of quaternary ammonium groups resulting to precise IEC, water uptake and anionic conductivity without batch-to-batch variations and compatible with industrial manufacturing processes for use as membranes or ionomers in low temperature and high temperature polymer electrolyte membrane fuel cells.
    Type: Application
    Filed: March 25, 2022
    Publication date: September 28, 2023
    Inventors: Christos L. Chochos, Panagiotis Bexis, Konstantinos Gournas, George Paloumbis, Vasilis Gregoriou
  • Publication number: 20230302442
    Abstract: A pipette tip extension attachable to a pipette tip with the pipette tip extension having a proximal end, a distal end, and exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall having an outer side and inner side and forming at the proximal end a reception aperture for inserting a pipette tip, and at a distal end a dispense aperture. An inner cavity is enclosed by the inner side of the exterior wall and one or more distance elements connected to the inner side of the exterior wall. The distance element(s) being configured to position a pipette tip within the inner cavity and to establish fluid uptake area adjacent the inner side of the exterior wall with the fluid uptake area extending from the dispense aperture towards the reception aperture and being in fluid connection with the surrounding atmosphere at the reception aperture.
    Type: Application
    Filed: December 29, 2022
    Publication date: September 28, 2023
    Applicant: TECAN TRADING AG
    Inventor: Adrian SAGER
  • Publication number: 20230302443
    Abstract: A test strip device including a housing, at least one retention arm, an ejection tab, and a viewing window. The housing includes a channel extending through the housing, with an opening at a first end of the housing, the channel being configured to receive a test strip therein. The at least one retention arm is arranged within the channel and configured to retain the test strip within the channel. The ejection tab is slideably arranged within the housing and configured to slide the test strip through the channel and out of the opening. The viewing window is arranged within the housing and configured to allow a results region of the test strip disposed within the channel to be viewed through the viewing window.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 28, 2023
    Inventor: Dan Aziz
  • Publication number: 20230302444
    Abstract: This disclosure provides systems and methods for the production of formulations of active pharmaceutical ingredients (APIs). In some embodiments, the disclosure provides an automated medicine formulation system comprising a portable and self-contained API formulating apparatus where the API and excipients are formulated to make a drug product meeting drug quality and safety specifications. The automated formulation system produces liquid formulations including, for example, injectable and intravenous medicines. The systems are capable of producing a plurality of individual sterile injectable doses of drug comprising a specific API and excipient(s), which can be formulated on demand in a GMP and FDA acceptable manner.
    Type: Application
    Filed: March 24, 2023
    Publication date: September 28, 2023
    Applicant: ODH IP CORP.
    Inventors: Mahdi Ramezani, Akshaya Nair, Gordon Brezicki, Jonathan Samuel, Alec Nicewick, Griffin Whittredge
  • Publication number: 20230302445
    Abstract: A microfluidic system may include a microfluidic chip having a non-conductive substrate and wells connected in common to a microfluidic channel within the non-conductive substrate. Each well may have a galvanic contact with a first portion at an upper surface of the sample well and a second portion that extends into the non-conductive substrate. A plurality of electrodes may be provided as part of an electrical interface, with each electrode configured to contact a respective galvanic contact of the microfluidic chip. The electrical interface may also include at least one shared power amplifier that is configured to generate a power signal (e.g., constant current, constant voltage, pulsed power signal). A selector may be configured to receive the generated power signal from the shared power amplifier and configured to select at least one of the plurality of electrodes and output the received power signal thereto.
    Type: Application
    Filed: March 22, 2022
    Publication date: September 28, 2023
    Inventors: Allen Curtis Dennison, Vladimir Krasheninin, Stephen J. Allen, Thomas Rawlins, Richard Raymond Harazin, Michael W. Belobraydich, Narendra Vaidya, Shreyas Milankumar Shah, Thomas John Martiska
  • Publication number: 20230302446
    Abstract: A cartridge for detecting a target analyte according to an embodiment of the present disclosure comprises a sample containing part in which a sample is receivable; a sample drawing part in which the sample is drawn up into a pipette tip; and a sample flowing channel via which the sample containing part and the sample drawing part are in fluid communication with each other, wherein a sample flows into a pipette tip from the sample containing part via the sample flowing channel by a negative pressure delivered through the pipette tip entering the sample drawing part in a state where the pipette tip is in close contact with an outlet of the sample flowing channel.
    Type: Application
    Filed: March 25, 2022
    Publication date: September 28, 2023
    Applicant: SEEGEME. INC.
    Inventors: Phillip HALBERT, Aaron Matarese
  • Publication number: 20230302447
    Abstract: An apparatus and method for bio-particle detection are provided. The apparatus for bio-particle detection includes: a bio-particle detection chip including a substrate having a plurality of through-hole groups, each through-hole group of the plurality of through-hole groups including through-holes which pass through the substrate from a first surface of the substrate toward an second surface of the substrate opposite to the first surface, and which are configured to accommodate a sample solution loaded therein; and a processor configured to determine a number of through-holes, among the through holes of at least one through-hole group of the plurality of through-hole groups, having a target material encapsulated therein, based on at least one of an electrical signal and an optical signal corresponding to the through-holes of the at least one through-hole group, and to estimate a concentration of the target material based on the determined number.
    Type: Application
    Filed: August 16, 2022
    Publication date: September 28, 2023
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Won Jong JUNG, Hyeong Seok JANG, Kak NAMKOONG, Hyung Jun YOUN, Jae Hong LEE
  • Publication number: 20230302448
    Abstract: In a nucleic acid amplification chip, a filter is provided inside or outside a PCR reaction container with respect to a micro-flow channel. Here, the filter is fixed to the PCR reaction container via a fixing portion. In this case, since the fixing portion is formed, the reliability of fixing the filter to the PCR reaction container can be improved. For this reason, the leakage of an evaporated sample solution (aerosol) from a gap between the filter and the PCR reaction container can be suppressed. Further, since the fixing portion is formed, the leakage of the evaporated sample solution (aerosol) can be suppressed without increasing the thickness of the filter, so that the filter can be made thin. As a result, the overall thickness of the nucleic acid amplification chip can also be reduced, so that the degree of freedom in designing the nucleic acid amplification chip is improved.
    Type: Application
    Filed: August 6, 2021
    Publication date: September 28, 2023
    Applicant: KYORIN PHARMACEUTICAL CO., LTD.
    Inventors: Keisuke GOHDA, Kentaro UMEI
  • Publication number: 20230302449
    Abstract: The present disclosure relates to a biochip comprising at least one coupling arrangement for electrical stimulation of biological material or for electrical measurements on the biological material, the biochip comprising: a support structure arranged at and/or in the coupling arrangement; and a layer, a layer surface of which is arranged at the coupling arrangement, and an opposite layer surface of which forms a coupling surface for stimulation of the biological material and/or for measurement on the biological material. To achieve improved stimulation efficiency of the biochip, it is proposed that the layer has ferroelectric properties.
    Type: Application
    Filed: June 5, 2023
    Publication date: September 28, 2023
    Inventors: Maximilian BECKER, Claus BURKHARDT
  • Publication number: 20230302450
    Abstract: A point-of-care testing (POCT) quantitative pathogen detection device is provided, without the aid of any detectors. In an illustrative embodiment, a POCT pathogen detection device includes an inlet microwell for receiving a substance, the inlet microwell connected to a distribution channel to distribute the substance to an analyzing component. The device also includes an analyzing component. that includes a first pathogen detection component. The first pathogen detection component includes a platinum nanoparticle-labeled DNA-probe configured to propel a dye through a bar-chart channel when a pathogen in the substance reacts platinum nanoparticle-labeled DNA-probe. The platinum nanoparticle-labeled DNA-probe is configured to react with a first pathogen. The device also includes at least one magnet configured to keep unreacted platinum nanoparticle-labeled DNA-probe in a sample recognition microwell, thereby inhibiting propulsion of the dye into the bar-chart channel when the pathogen is not detected.
    Type: Application
    Filed: June 1, 2023
    Publication date: September 28, 2023
    Inventors: XiuJun Li, Delfina Dominguez, Xiafeng Wei
  • Publication number: 20230302451
    Abstract: The invention relates to microfluidic methods; and modular devices and systems for implementing the methods. The invention also relates to uses of these devices and systems for biological analyses.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 28, 2023
    Inventors: Florian Hollfelder, Tomasz Kaminski, Joachim De Jonghe
  • Publication number: 20230302452
    Abstract: A method of maintaining at least one component in an aqueous microdroplet dispersed in conditioned oil to form an emulsion is provided.
    Type: Application
    Filed: August 10, 2021
    Publication date: September 28, 2023
    Applicant: LIGHTCAST DISCOVERY LTD
    Inventors: Nele DIECKMANN, Gianmarco MASTROGIOVANNI, Emma Louise TALBOT, William Michael DEACON
  • Publication number: 20230302453
    Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.
    Type: Application
    Filed: April 24, 2023
    Publication date: September 28, 2023
    Applicant: ABBOTT LABORATORIES
    Inventors: Jeffrey B. Huff, Mark A. Hayden, Peter J. Karabatsos, Andrew Fischer, John M. Robinson, Shelley R. Holets-McCormack, Sophie Laurenson
  • Publication number: 20230302454
    Abstract: The present teachings relate to a method of making a biological sample collection container, an internally coated biological sample collection container, and uses of the same, particularly for omic analysis. A reagent (or a reagent precursor) is deposited in a liquid state at least partially along at least one side wall of the container. The reagent precursor is dried to form a dried coating having a predefined pattern and topology along at least a portion of the at least one side wall. A container thus results having a coating that includes, in a dried state, a stabilizer agent, or reaction product of a stabilizer agent and an anticoagulant, and upon collection of a sample enables stabilization of any present white blood cells, cell-free nucleic acids, extracellular vesicles, circulating tumor cells, proteins, metabolites, lipids, or any combination thereof, and preserving them in sufficient quantity and quality for omic analysis.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 28, 2023
    Inventors: Sean Salamifar, Nick George, Brad Hunsley
  • Publication number: 20230302455
    Abstract: A container or consumable like a reaction tube for use in diagnostic assays. The present disclosure provides a system for fluid handling and transport, comprising a plate with at least one cavity for receiving a fluid which is surrounded by a rim, and a separate cover comprising a centrally arranged surface as a sealing element which is surrounded by a rim, wherein the plate or the cover comprise at least one snap-fit mechanism for connecting at least two plates, at least two covers or a plate and a cover, wherein the snap-fit mechanism extends upwards or downwards from the surrounding rim of the plate or the cover, and wherein the rim of the plate or cover which is to be connected is configured for accommodating the snap-fit mechanism of an upper or lower plate or cover in a retaining element arranged at the rim.
    Type: Application
    Filed: March 23, 2023
    Publication date: September 28, 2023
    Inventors: Andreas Meyer, Hannes Kirzinger
  • Publication number: 20230302456
    Abstract: A configurable port fitting for a container, such as a bioprocess bag, has one or more O-ring grooves and two opposing locking arms (e.g., 604). The port fitting is mounted onto the container by (i) inserting one end of the port fitting into a port in the container such that O-ring(s) form seals between the O-ring grooves and the container and (ii) rotating the port fitting to engage the locking arms with two opposing retention clips (e.g., 506) of the container. Some port fittings are fixed port fittings that provide a fixed opening into the container. Other port fittings are port sizers that receive a valve connector that enables flow control between closed and open positions. Port fittings of different sizes enable different flow rates. Some port fittings (and other connectors) have a threaded tube barb that receives a threaded tube retainer that secures tubing in place over the barb.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 28, 2023
    Applicant: Evolution Design & Development LLC
    Inventors: Anthony P. Pagliaro, JR., Clemens E. Zoellner, Scott R. Johnson
  • Publication number: 20230302457
    Abstract: The present invention discloses a multi-function polymerase chain reaction device, which utilizes a movable multi-functional top cover to make an equipment can selectively perform variable temperature PCR (Polymerase Chain Reaction) or constant temperature PCR, which the flexibility of test-application is highly raised.
    Type: Application
    Filed: June 30, 2022
    Publication date: September 28, 2023
    Inventors: Chi-Sheng TAI, Shih-Jeng DAI, Bo Chen LIN
  • Publication number: 20230302458
    Abstract: In a hulling apparatus for producing hulled spelt seed including a lower course hulling device, and a method for producing hulled seed of a spelt grain, the hulling apparatus contains two disks, as rotor and stator, which are movable relative to each other, wherein at least one disk can be driven about a vertical rotation axis, and the disks enclose a flat annular working chamber between disk faces which face each other and are vertically spaced apart from each other, for receiving spelt products to be hulled, wherein at least one of the disk faces has a surface made of a plastic material, and the temperature of the apparatus can be controlled in the region of at least one of the disk faces.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 28, 2023
    Applicant: Lehner Maschinenbau GmbH
    Inventors: Ralf HUEBNER, Helmut LEHNER
  • Publication number: 20230302459
    Abstract: There is provided an apparatus and method for comminuting a material. The apparatus may comprise a chamber and an inner surface with a plurality of protrusions, and a hammer positioned within said chamber comprising an outer surface having a plurality of second protrusions configured to engage with the first protrusions. The outer and inner surfaces may be separated by a gap distance which defines a comminution zone. The anvil may be rotated to cause a material to be comminuted as the material passes through the comminution zone.
    Type: Application
    Filed: July 22, 2021
    Publication date: September 28, 2023
    Inventor: Lawrence K. NORDELL
  • Publication number: 20230302460
    Abstract: Method and system for generating information relating to an internal state of a tumbling mill (10) for grinding a charge of material (30) by tumbling the material in a rotating shell (20).
    Type: Application
    Filed: April 9, 2021
    Publication date: September 28, 2023
    Inventor: Tim Sundström
  • Publication number: 20230302461
    Abstract: A magnetic stand includes: a base having an insertion hole into which a container is to be inserted, the insertion hole extending along a first axis; and a magnet provided on the base and having a magnetization that applies a magnetic field to the insertion hole. The magnet is disposed such that magnetic poles thereof face directions different from that of the container. When a plane including the first axis and determined such that a normal line of the plane is orthogonal to the first axis and passes through a center of the magnet is taken as a reference plane, and the magnetization is projected onto the reference plane, an angle formed by the first axis and the magnetization projected onto the reference plane is more than 0° and 90° or less.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 28, 2023
    Inventors: Fumio TAKAGI, Hiroshi TAKIGUCHI
  • Publication number: 20230302462
    Abstract: One or more surfactants and one or more adjuvant gases in the hydrometallurgical and pyrometallurgical processes, which are added thereto in the state of nanobubbles and microbubbles, both the gases used and the nanobubbles and the microbubbles thereof, are in a variable proportion depending on the physicochemical requirements of each of the stages of the process where it is applied. The nanobubbles and microbubbles, of the proposed composition, make it possible to significantly increase the physicochemical properties of these gases such as: flotation speed, oxidizing power, reducing power, contact area provided and coalescence speed.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 28, 2023
    Inventors: Eugenio Ovidio LIZAMA MORENO, Rene Eduardo DAHMEN LEMUS
  • Publication number: 20230302463
    Abstract: Described herein are methods for flotation of an ore. The methods include providing an aqueous suspension having an ore in the form of particles, water, and a first frothing agent including a poly(tetrahydrofuran), in a flotation cell to obtain a provided aqueous suspension. The method further includes introducing air into the provided aqueous suspension to obtain a froth. Further described herein are specific aqueous suspensions having ore particles and poly(tetrahydrofuran) and uses of poly(tetrahydrofuran) as a frothing agent for an aqueous suspension having an ore in the form of particles.
    Type: Application
    Filed: July 27, 2021
    Publication date: September 28, 2023
    Inventors: Graeme Levi Stewart, Alexej Michailovski, Yoav Zuk
  • Publication number: 20230302464
    Abstract: A process or use of at least one hydroxyl ether diamine for improving a process for froth flotation of silicates. Compared to the benchmark ether monoamines, ether diamines or mixtures thereof, the selectivity performance of the hydroxyl ether diamines is significantly better, delivering higher recoveries for the mineral of interest.
    Type: Application
    Filed: March 25, 2022
    Publication date: September 28, 2023
    Applicant: Clariant International, Ltd.
    Inventors: Adriana Grossmann, Tobias PLATEN, Klaus RAAB, Claudio Wagner DA SILVA, Leandro Seixas BICALHO, Pedro Martins de Almeida ROLLO