Abstract: A system and method for monitoring the blood pressure of a patient that allows for a device sensor to be recalibrated according to atmospheric pressure without removing the device sensor from inside the patient. This permits quickly monitoring the blood pressure of a patient if a re-zero is needed. The invention has a blood pressure monitor (BPM) that obtains an atmospheric pressure observation. The atmospheric pressure observation is adjusted and stored to memory as a zero value. The zero value is retrieved to recalibrate the system and method if a device sensor has been disconnected from and reconnected to the same or a different BPM, the patient has been moved such that the surroundings have been altered to make it necessary to recalibrate according to atmospheric pressure, and/or the device sensor has been connected to a different patient care monitor.

Abstract: This disclosure enables non-invasively obtaining a blood pressure measurement of a person in a repeatable manner in order to provide frequent updates to the blood pressure measurement, while 1) being comfortable for the person when the person is conscious, 2) enabling relaxation of the person, 3) allowing the person to fall asleep, or 4) avoiding waking the person if the person is already asleep. After a first set of blood flow waveform data associated with a blood pressure measurement has been acquired (304), a second set of waveform data is received (306), a parameter change in the second waveform data is identified (308), the parameter change is correlated to the blood pressure measurement (310) so as to generate a virtual blood pressure (312), and an action is taken (314) based on the virtual blood pressure.

Abstract: An apparatus comprising an inflatable member, a sensor and a controller. The inflatable member is configured to apply pressure to a portion of a body of a patient and is configured to be placed in a deflated configuration, a first inflated configuration, and a second inflated configuration. A pressure within the inflatable member when the inflatable member is in the second inflated configuration is greater than a pressure within the inflatable member when the inflatable member is in the first inflated configuration. The sensor is configured to detect vibration. The controller is operatively coupled to the sensor and to the inflatable member. The controller is configured to prevent the inflatable member from being placed in the second inflated configuration in response to the sensor detecting vibrations indicating movement of the body of the patient while the inflatable member is in the first inflated configuration.

Abstract: An apparatus comprising a monitor, a blood pressure measuring device, and a controller. The monitor is configured to estimate a blood pressure of a patient. The blood pressure measuring device is configured to measure a blood pressure of the patient. The controller is operatively coupled to the monitor and to the blood pressure measuring device. The controller is configured to cause the blood pressure measuring device to take a first blood pressure measurement of the patient in response to an estimated blood pressure deviating from a baseline. The controller is also configured to cause the blood pressure measuring device to take a second blood pressure measurement of the patient in response to an estimated blood pressure deviating from a second baseline different than the first baseline.

Abstract: A collar device is described herein comprising a spacer component including at least one emitter and at least one detector, the spacer component comprising a plurality of optical pathway elements, wherein the plurality of optical pathway elements comprises a first optical pathway element and a second optical pathway element. The spacer component is secured to the device, wherein the first optical pathway element extends from an emitter, wherein the second optical pathway element extends from a detector. The emitter is configured to project light through the first optical pathway element toward skin tissue of an animal. The detector is configured to detect portions of the light reflected by the skin tissue back through the second optical pathway element. One or more applications running on at least one processor of the device is configured to use information of reflected light to determine a biological metric.

Abstract: A device for monitoring a health parameter of a person is disclosed. The device includes a semiconductor substrate including at least one transmit component and multiple receive components, at least one transmit antenna configured to transmit millimeter range radio waves over a 3D space below the skin surface of a person, and multiple receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves, wherein the semiconductor substrate includes circuits for processing signals received on the multiple receive antennas, wherein the semiconductor substrate includes at least one output configured to output a signal that corresponds to a health parameter of a person in response to received radio waves, and wherein the at least one transmit antenna is collocated with the at least one transmit component and the multiple receive antennas are collocated with respective ones of the multiple receive components.

Abstract: The present disclosure provides a steerable and adjustable recorder pulse pillow for Traditional Chinese Medicine pulse diagnosis, and relates to the technical field of recorder pulse pillows. The steerable and adjustable recorder pulse pillow for Traditional Chinese Medicine pulse diagnosis comprises a main body, wherein a platform is installed right above the main body. The top surface of the platform is installed with a recording device. The bottom of the recording device is provided with a rotary disc. The rear end surface of the recording device is provided with an operating button. The rotary disc is fixedly connected with a micro-motor driving wheel inside the recording device. The micro-motor is electrically connected with a rotary knob of the recording device.

Abstract: This invention is related to artificial intelligent (AI) system with biodegradable endovascular nanoscale-structured flowmeter layer for monitoring cerebral blood flow during mental performance, blood flow through in-stent re-stenosis (ISR) and thromboembolism. The invention is based on blood flow inducing changes in magnetization of nanoscale microwave ferrites. These changes in magnetization, then interact with the microwave in a frequency-dependent manner using a microprocessor for processing and transmission via cellular phone network to human-machine interface for control of computers, machines or weapon systems. It detects reduction of blood flow through ISR and microembolic signals due to thromboembolism of the vessel much earlier before severe symptoms develop.

Abstract: A biological measurement device includes a light emitting device, a sensor, and a processing circuit. The light emitting device irradiates a first region and a second region, which is located on an upper side relative to the first region, of a forehead of a subject with light. The sensor detects first scattering light generated by the light incident on the first region and second scattering light generated by the light incident on the second region and outputs detection signals according to intensities of the first and second scattering light. The processing circuit selects one of the first and second regions as a target region based on the detection signals and/or an image signal indicative of an image including a face of the subject and generates and outputs brain activity data indicative of a state of brain activity of the subject based on the detection signal in the selected target region.

Abstract: A device for detecting stenosis comprising disposable components to ensure function and sanitary conditions, said device having a disposable sensing pad, a disposable piezo assembly, and a disposable sensing pod, wherein the entire device can be disposed of after a predetermined number of uses to ensure accuracy of results and of sanitary conditions.

Abstract: An intracranial pressure monitoring device includes a housing defining a first internal chamber, a plurality of strain gauges disposed on an inner surface of a diaphragm defined by a wall of the first internal chamber, a device for generating orientation signals, and circuitry coupled to the plurality of strain gauges and to the device. The circuitry is configured to generate intracranial pressure data from signals received from the plurality of strain gauges, generate orientation data based on the orientation signals received from the device, and store the intracranial pressure data and the orientation data in a computer readable storage such that the intracranial pressure data and orientation data are associated with each other.

Abstract: The disclosure relates to new methods for calibrating or adjusting a bioimpedance measuring device. Furthermore, the present disclosure relates to a medical set or system, a medical measuring standard, a method for testing a bioimpedance measuring device, and a bioimpedance measuring device.

Abstract: A method of measuring a bio signal using a bio signal measuring apparatus includes: positioning electrodes included as part of the bio signal measuring apparatus to contact a surface of an examinee; switching an impedance measurer included as part of the bio signal measuring apparatus and including a voltmeter and a current source; measuring a first impedance value of the examinee while operating the impedance measurer according to a first mode; switching the impedance measurer to a second mode; measuring a second impedance value of the examinee while operating the impedance measurer according to a second mode; and obtaining bio impedance of the examinee based on the first and second impedance values and an internal impedance of the current source.

Abstract: A method and apparatus for obtaining biomarkers of microvascular or macrovascular function in an individual includes receiving a continuous blood-oxygen-level-dependent (BOLD) cardiac magnetic resonance (CMR) image series spanning a plurality of cardiac cycles and respiratory states, generating a plurality of phase-matched single-cycle image series that are temporally aligned at a plurality of phases forming phase-vectors, performing a Windowed Matrix Decomposition (WMD) operation on the images of each phase-vector to generate low-rank image components, constructing a composite single-cycle image series utilizing the low-rank image components, and computing one or more oxygen perfusion biomarkers utilizing the composite image series.

Abstract: The present disclosure discloses a brain atlas individualization method and system based on magnetic resonance and a twin graph neural network. Firstly, a feature is extracted from resting-state functional magnetic resonance imaging (rs-fMRI) by utilizing functional connectivity based on a region-of-interest, and at the same time, Fisher transformation and exponential transformation are performed on the feature; secondly, a corresponding adjacent matrix is extracted from T1-weighted magnetic resonance data in a data set; and then the twin graph neural network is designed for training and testing with the transformed feature and the adjacent matrix as inputs and a group atlas label and a sampling mask as outputs.

Abstract: According to some aspects, a magnetic resonance imaging system capable of imaging a patient is provided. The magnetic resonance imaging system comprising at least one B0 magnet to produce a magnetic field to contribute to a B0 magnetic field for the magnetic resonance imaging system and a member configured to engage with a releasable securing mechanism of a radio frequency coil apparatus, the member attached to the magnetic resonance imaging system at a location so that, when the member is engaged with the releasable securing mechanism of the radio frequency coil apparatus, the radio frequency coil apparatus is secured to the magnetic resonance imaging system substantially within an imaging region of the magnetic resonance imaging system.

Abstract: Disclosed are methods and devices for detecting retained surgical items or other objects having a magnetic signature within a corpus of a patient. The device can comprise a handle, a shaft extending from the handle, and a distal sensing portion positioned distally of the shaft. The distal sensing portion can comprise one or more gradiometers comprising a plurality of magnetometers. The device can further comprise one or more output components configured to generate a user output to alert a user of a detected object.

Abstract: Provided are a device and a method for outputting a respiration signal together with an electrocardiogram signal. The respiration signal output device includes an electrode signal measurement unit for measuring a signal between at least two electrodes attached to the body of a subject, a respiration signal generation unit for generating a respiration signal of the subject based on the measured signal, an electrocardiogram signal generation unit for generating an electrocardiogram signal of the subject based on the measured signal, and an output unit for outputting the electrocardiogram signal and the respiration signal.

Abstract: Various examples are provided related to detection and measurement of respiratory parameters. In one example, a system for monitoring an individual's respiration includes a thermal sensor that can detect CO2, an optical sensor, and image processing circuitry that can determine a parameter of CO2 gas being exhaled about a mouth of the individual using a thermal image captured by the thermal sensor and optical image(s) captured by the optical sensor. In other examples, a system includes an arrangement of thermal sensors and/or optical sensors that can monitor gas being exhaled about a mouth of the individual. In another example, a system includes an arrangement of thermal and optical sensors and image processing circuitry that can determine, e.g., a flow field and/or distribution of gas being exhaled about a mouth of the individual based upon thermal images and optical images captured by the arrangement of thermal and optical sensors.

Abstract: A device (100) is disclosed for obtaining a breath sample from a patient, The device comprises a mask or mouthpiece (101) for receiving breath from a patient; an outlet (102) through which breath is exhausted from the device (100); a sampler (110); and a sample container (113). The sampler (110) comprises a distal portion configured to protrude into a flow of breath from the mask or mouthpiece (101), and a sampler opening (118) in the distal portion for obtaining a breath sample. The sample container (113) is in communication with the sampler (110) for receiving the breath sample from the sampler (110).

Abstract: A mouth cavity attachment tool (1A) is attachable to a mouth cavity (M) of a person (P) under examination. The mouth cavity attachment tool (1A) includes a partitioning portion (10A) and a gap forming portion (11A). The partitioning portion (10A) partitions a mouth cavity (M) into a first portion (M1) where objects of measurement of halitosis are located and a second portion (M2) communicating with a pharynx (6) of the person (P) under examination. The gap forming portion (11A) is connected to the partitioning portion (10A) and forms gaps (G) in spaces to the objects of measurement. Since the mouth cavity attachment tool (1A) includes the partitioning portion (10A) partitioning the mouth cavity (M) into a first portion (M1) where tooth rows (2) and gums (3) are located and a second portion (M2) communicating with the pharynx (6) of the person (P) under examination, halitosis can be detected accurately.

Abstract: An operation apparatus is provided that includes a plurality of sensors, a range setting portion, and an arithmetic portion. The plurality of sensors are worn on a wrist, and output a sensor signal according to a motion of a tendon of the wrist. The range setting portion sets an operation learning time range including time of a feature point of a measurement signal based on the sensor signal. The arithmetic portion learns an operation based on the measurement signal based on the sensor signal of the plurality of sensors in the operation learning time range. The arithmetic portion then estimates the operation based on criteria according to the learned content.

Abstract: A real-time human activity recognition (rtHAR) engine embedded in a wearable device monitors a user's activities through the wearable device's sensors. The rtHAR uses the signals from the sensors to determine where the wearable device is relative to the user's body, and then determines the type of activity the user engages in depending upon the location of the wearable device relative to the user's body. The rtHAR is preferably installed on the wearable device as an embedded system, such as an operating system library or a module within software installed on the wearable device, so as to improve the quality of direct feedback from the wearable device to the user, and to minimize the amount of data sent from the wearable device to external archival and processing systems.

Abstract: An exemplary interactive hearing services kiosk includes one or more walls configured to define a space; a first door providing access to the space; one or more media devices; one or more user display screens, at least one of the one or more user display screens is located on the outside of at least one of the one or more walls of the kiosk so as to define an outside display screen; and a controller. The controller may be configured to display, via the outside display screen, one or more prompts that are associated with one or more hearing services and receive input that is responsive to the one or more prompts. The input may include at least one response via the one or more media devices. The controller may be configured to validate the input and generate one or more recommendations based on a validated input.

Abstract: Described herein are variations of a cortisol monitoring system, including a cortisol monitoring device. For example, a cortisol monitoring device may include a skin-penetrating microneedle array for use in measuring cortisol, such as in a continuous manner. The microneedle array may include, for example, at least one microneedle comprising a working electrode comprising a cortisol-sensing aptamer that selectively and reversibly binds to cortisol. The microneedle array may include, for example, at least one microneedle including a tapered distal portion having an insulated distal apex, and an electrode on a surface of the tapered distal portion located proximal to the insulated distal apex. At least some of the microneedles may be electrically isolated such that one or more electrodes is individually addressable.

Abstract: Disclosed herein are systems and methods for a continuous analyte monitoring system for measuring a concentration of a first analyte and concentration of a second analyte in a host. One such system utilizes a working electrode and a reference electrode to measure glucose concentration and oxygen concentration in bodily fluid of a host. The system includes a sensor control circuit that applies a first bias condition to the sensor to measure a first signal generated by the sensor indicative of a concentration of the first analyte. The sensor control circuit also applies a second bias condition to the sensor to measure a second signal generated by the sensor indicative of a concentration of a second analyte at the host.

Abstract: The present invention is to provide an apparatus and a method for obesity prevention and weight regulation, which can efficiently regulate and manage gaining and losing weight by maintaining a blood sugar level suitable for a personal situation through regulation of eating food and activity regulation by using a blood sugar value measured using noninvasively measuring blood sugar.

Abstract: There is provided a glucose sensor system comprising: a transmitter (2) for containing a battery (212), the transmitter being for placement on top of patient skin; a transcutaneous connector (3) comprising at least one conductive path; and an implantable monolithic integrated circuit (1) for placement beneath the patient skin, wherein the implantable monolithic integrated circuit comprises a potentiostat and an electrochemical sensing element; wherein the potentiostat is electrically coupled to the transmitter (2) via the transcutaneous connector (3), and the electrochemical sensing element is configured to sense glucose concentration and generate an electrical signal representative of the glucose concentration, and wherein the potentiostat is electrically connected to the electrochemical sensing element.

Abstract: Embodiments of the present disclosure, inter alia, are directed to a one piece continuous glucose monitoring (CGM) device (device or sensor) and a fully disposable, one piece, mounting unit for mounting the CGM device, is provided. The device and the mounting unit, in some embodiments, are pre-assembled in the factory to a one piece, disposable, mounting assembly. The mounting assembly, can be comprised of sealed compartment that includes a portion of the sensor and a non-sealed compartment that includes another portion of the sensor. The mounting assembly can be fully automatic, at a button press the sensor is adhered to the skin, and the sensor probe is inserted into the subcutaneous tissue.

Abstract: Embodiments of the present disclosure relate to systems, devices and methods for continuous glucose monitoring. In some embodiments, a continuous glucose monitoring (CGM) device is provided that includes a subcutaneous implantable electrochemical sensing probe (sensor). The sensor is planar and comprises counter and working electrodes that are deposited at both sides of the sensing probe. A biocompatible layer deposited at the entire sensor circumference minimizes inflammatory reaction. A reel to reel production process provides “per sensor” layers' deposition at predefined spots on a base sheet during displacement between production stations. Production processes are conducted initially at one side of the base sheet followed by production processes on the opposite side.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract: Disclosed are a noninvasive blood glucose measurement apparatus and method using multiple sensors. The noninvasive blood glucose measurement apparatus includes: a first light source unit configured to irradiate light to the biological tissue, a second light source unit configured to irradiate light to the biological tissue, a first receiving unit configured to receive a photoacoustic and/or light transmission signal generated by the light, a second receiving unit configured to receive a light reflection signal reflected by the biological tissue, and a measurement unit configured to measure light reflection characteristics of the biological tissue by using the light reflection signal, measure photoacoustic and/or light transmission characteristics of the biological tissue, and measure blood glucose of the biological tissue on the basis of the light reflection characteristics and the photoacoustic and/or light transmission characteristics.

Abstract: A user device (e.g., a mobile device) receives testing period data during a testing period. The user device determines that a portion of the data is missing based on an analysis of the received testing period data. The analysis of the received data includes an analysis of one or more blood glucose levels and an analysis of the dietary intake data, the medication data, and the activity data. The user device imputes the missing portion of the data with substitute data determined using predictive learning. The user device calculates a confidence level associated with the substitute data. The user device identifies, using the substitute data, a progression or a regression in a diabetic condition associated with the user.

Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor for sensing an analyte level in a bodily fluid of a subject. In particular, disclosed herein are various embodiments of applicators, and components thereof, designed to reduce trauma to tissue of a sensor insertion site and to increase the likelihood of a successful sensor insertion.

Abstract: A system for measuring at least one physiological parameter includes a wearable device configured to be secured to a subject’s foot and a sensor component that is removably securable to the wearable device. The wearable device includes a base configured to contact a bottom of the subject’s foot, a wall extending outward from the base and configured to surround a heel of the subject’s foot, and a sensor component that is removably securable to the wearable device. The sensor component includes a sensor hub configured to be removably secured to the wearable device, a sensor strap configured to be wrapped around the subject’s foot and secured to the wearable device, an emitter configured to emit optical radiation into tissue of the subject’s foot, and one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through the tissue.

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Abstract: The present invention is directed to devices for measuring reactions between a recognition element and a biological fluid (biomarker) to determine user well-being. The present invention features a sensor for analyzing a plurality of features of a reaction between an enzyme and a biomarker to measure a user's health. The sensor may comprise a substrate with an enzyme source and a drain. The enzyme source may comprise an enzyme path leading to a substrate surface to direct the enzyme to react with the biomarker to become a post-reaction mixture. The drain may comprise a drain path. The post-reaction mixture may travel from the substrate surface through the drain path to the drain. The sensor may further comprise an electronic gate disposed above the surface of the substrate for measuring the plurality of features. The sensor may be wearable on a skin surface of the user.

Abstract: The invention relates to a device for detecting at least one substance in the blood of an individual, which comprises a main body and a replaceable sterile head, said replaceable head comprising: means for disinfecting the skin of said individual; means for collecting blood from said individual; means for collecting said blood, in which the replaceable head comprises means for diluting the blood and in which the replaceable head is functionally connected to the main body of the device

Abstract: A method and device for collecting a blood sample from a subject are provided. The handheld device comprises an actuator assembly and a body housing the actuator assembly and having a cavity configured to releasably receive a cartridge to couple to the actuator assembly. The cartridge is configured to capture the blood sample from the subject when used with the device. The blood sample is collected when the device determines that the cartridge is properly positioned over a vein or capillaries of the subject.

Abstract: An insert for a catheter system may include a distal end, a proximal end, and a middle portion disposed between the distal end and the proximal end. The distal end of the insert may include a male port, and the proximal end of the insert may include a female port opposite the male port. The insert may be configured to extend through an adapter and/or a needleless connector of a catheter system to reduce exposure of the adapter and/or the needleless connector to blood, which may flow through a lumen of the insert. The lumen of the insert may extend through the male port, the middle portion, and the female port.

Abstract: A body fluid sampling device (100) provides a user with the ability to sample and/or analyze a fluid in the body (body fluid) such as blood, puss or venom. The device (100) includes at least: a body fluid reservoir for containing the sampled body fluid and a fluid extraction mechanism including at least one conduit or needle connected to a conduit injection and retraction mechanism and a vacuum reservoir. After connecting the body fluid reservoir to the sampling device, a vacuum seal of the body fluid reservoir is adapted to be broken so as to cause the sucking of the body fluid into the body fluid reservoir. The sampling device (100) aids in executing a method (200) of the invention consisting of collecting body fluid such as capillary blood samples without the intervention of medically trained personnel.

Abstract: This computer-implemented method for providing an automated prediction of a change of a state of fatigue of a subject carrying out a visual task involving any kind of visual content comprises: providing a plurality of input data, relating to the subject, to a fatigue state change predictive model, wherein the plurality of input data comprises at least one subjective measurement relating to the subject and/or at least one objective measurement relating to the subject and/or at least one other subject-related datum; obtaining, by a processor implementing the model, a value representing a level of change of the state of fatigue of the subject.

Abstract: A system of hardware and software that captures and processes in real time biometric data of patient responses and reactions to tablet-based valenced pictorial stimuli to facilitate diagnosis of mental health conditions of the patient including Autism Spectrum Disorder (ASD), Attention-Deficit Hyperactivity Disorder (ADHD), Traumatic Brain Injury (TBI), and Post-Traumatic Stress Disorder (PTSD) is provided. Via transparent, non-invasive biometrics induced by pictorial stimuli, the system removes potentially threatening testing instrument characteristics that can invalidate authentic assessment. The system will mitigate or remove other threats to assessment validity including subjective judgments as well as bias on the part of the examiners who are completing subjective surveys. The biometric assessment is incorporated within a variety of engaging game formats that appeal to males and females of nearly any age that speak a variety of languages and encompass a wide spectrum of demographics and ethnicities.

Abstract: An AI test and analysis system for psychology preference is provided. By using brainwave detectors, the emotions and characters of the testers are connected. Variations from the brainwaves in pre-test and formal-test are used for analyzing of AI and big data as a base for determining human characters and emotions. These can be used to compensate insufficiency of conventional analysis thereabout. The methodology is widely used in various fields, such as mindfulness, human resource, potentials of people, and sensibilities of human, etc. Only data obtained from brainwave detectors are used to have tendencies and preference of the testers to various objects, while brainwaves are real physical data from the testers.

Abstract: An information processing device 1X mainly includes a first acquisition means 14X, a second acquisition means 15X, and an estimation means 16X. The first acquisition means 14X acquires a measurement result of an intellectual ability of a measurement target person. The second acquisition means 15X acquires an estimation result of a mental state of the measurement target person, the mental state affecting the measurement of the intellectual ability. The estimation means 16X estimates the intellectual ability based on the measured result of intellectual ability and the estimation result of the mental state.

Abstract: The invention provides methods of identifying schizophrenia patients at risk for relapse. The invention also provides methods of early detection of schizophrenic relapse. The disclosed methods use monitoring of a subset of symptoms and/or one or more biomarkers. The symptom severity can be assessed using the Positive and Negative Syndrome Scale (PANSS) parameters. The methods of the invention can be used to provide early intervention to decrease or prevent relapse in schizophrenia patients.

Abstract: A wearable device wearable by a subject includes: a base; a first arm extending from the base; a second arm extending from the base; a first cable disposed along the first arm; a first sensor that is connected to a first end of the first cable, attached to a body of a subject who is wearing the wearable device, and detects physical body data of the subject; and a signal processor that is connected to a second end of the first cable and processes a detection signal from the first sensor. The signal processor is attached to the base.

Abstract: A head stage designed for non-surgical placement of EEG electrodes in small animals is disclosed. The head stage is connected to thin barbed pin electrodes of multiple lengths, such that they can be placed into the brain at the chosen depth. A miniature device comprising a wireless transmitter or data logger can be attached using magnets or connectors to the stage. When the head stage is placed on the head of a small animal and pressure is applied on the stage, the set of pin electrodes penetrate the skull, such that the stage becomes firmly fixed to the skull. Further, the device includes electrodes on its body that eliminate the need of wires for EEG recordings. When the capsule including sharp electrodes is pressed toward the skull, the electrodes penetrate the bone and fixes the capsule onto the skull for recording biopotential signals from the brain.

Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and the QRS interval signals indicating ventricular activity in the ECG waveforms. In particular, the ECG electrodes on the electrode patch are tailored to be positioned axially along the midline of the sternum for capturing action potential propagation in an orientation that corresponds to the aVF lead used in a conventional 12-lead ECG that is used to sense positive or upright P-waves.

Abstract: A monitoring system, an atrial fibrillation comprehensive management method and a monitoring data display method are disclosed. The atrial fibrillation comprehensive management method includes acquiring monitoring data of at least two vital sign parameters of a patient, where the at least two vital sign parameters comprise an electrocardiogram parameter; acquiring information of an atrial fibrillation event occurring in the patient; and displaying an atrial fibrillation comprehensive view according to the acquired information of the atrial fibrillation event and the acquired monitoring data of the at least two vital sign parameters. The atrial fibrillation comprehensive view includes a trend graph of at least two vital sign parameters, an atrial fibrillation event trend graph and an atrial fibrillation load graph.