Patents Issued in May 16, 2024
  • Publication number: 20240157010
    Abstract: A device for disinfecting objects comprising: a box-shaped body, at least one cold cathode lamp, mounted internally the box-shaped body and configured to irradiate the object to be disinfected with an ultraviolet radiation, one or more detection devices configured to detect environmental conditions, a control system configured to determine the activation time required for the at least one lamp to reach a nominal ultraviolet radiation output. The control system being further configured to control the power supply of the at least one lamp.
    Type: Application
    Filed: March 15, 2022
    Publication date: May 16, 2024
    Applicant: PRATRIVERO S.P.A.
    Inventor: Sergio Barberis Canonico
  • Publication number: 20240157011
    Abstract: A treatment device using active oxygen, the treatment device comprising: an ultraviolet transmission member; and a first chamber and a second chamber adjacent to each other separated by the ultraviolet transmission member, wherein the first chamber is capable of accommodating a treatment target and comprises an ozone generator, the second chamber comprises an ultraviolet light source, the ultraviolet light source is capable of irradiating a surface of the treatment target, which is accommodated in the first chamber, with ultraviolet light, and a distance between the ultraviolet transmission member and the surface of the treatment target can be adjusted to 10 mm or less.
    Type: Application
    Filed: January 23, 2024
    Publication date: May 16, 2024
    Inventors: TAKUMI FURUKAWA, MASAKI OZAWA, KAZUHIRO YAMAUCHI, KENJI TAKASHIMA, MOTOTERU GOTO, SHOTA KANEKO
  • Publication number: 20240157012
    Abstract: This invention relates to a system and method for detecting a sanitising process and for determining the efficiency of a sanitising process. A sanitising process detection system comprises a substrate with a sensor patch for detection of a disinfecting and/or sterilising agent. The sensor patch produces a colour change on exposure to disinfecting and/or sterilising agent. An optical detector is configured to detect the colour of the sensor patch at one or more predetermined time instants. A processor compares images of the colour of the sensor patch, at a predetermined instant in time, with a datum (such as control or the colour of the sensor patch prior to exposure to the disinfecting and/or sterilising agent) and its output is used to determine the presence of a colour change and thereby indicates the efficacy of the sanitising process.
    Type: Application
    Filed: March 9, 2022
    Publication date: May 16, 2024
    Inventors: Janice KIELY, Richard LUXTON, Graham MIMMS
  • Publication number: 20240157013
    Abstract: A composition and method for reducing odors and cleaning packing media and other components in a wet air scrubber using nonionic surfactants, amphoteric surfactants, and a source of humic acid. Preferred nonionic surfactants include regular and low foam nonionic surfactants. The source of humic acid is preferably organic peat humus. The treatment composition is added to water in the wet scrubber at a concentration of 50-1000 ppm. The treatment composition is a premixed composition in a single container, making it unnecessary to separately add ingredients to the water. The treatment composition is effective at reducing odors by at least 50% compared to no treatment. The treatment composition is also effective at significantly reducing foam levels, making it unnecessary to add a separate defoamer to the water being treated. The treatment composition does not need to use defoamers, enzymes, oxidizers, chlorine compounds, or strong acids to be effective.
    Type: Application
    Filed: March 15, 2023
    Publication date: May 16, 2024
    Inventors: Charles L. Davis, Adrian J. Denvir, Angela L. Delegard, Marta Drewniak
  • Publication number: 20240157014
    Abstract: A method and system of controlling a non-homogeneous cohort of ozone gas generating devices. The method comprises identifying, at a computing device, a plurality of ozone gas generating devices that constitute the non-homogeneous cohort, the plurality including at least a ceiling-mounted, an in-duct mounted and a portable ozone gas generating devices; continuously detecting, via at least one remote ozone gas sensor device located in a spatial area associated with the non-homogeneous cohort, in conjunction with one or more processors of the computing device, a concentration of ozone gas constituent within ozonated air of the spatial area; and instructing, by the one or more processors responsive to continuously detecting the concentration of the ozone gas constituent as being one of above and below a predetermined threshold concentration, at least one ozone gas generating device of the non-homogeneous cohort to increase or decrease rate of ozone gas generation associated therewith.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Inventors: PETER BIRCH, CHING KUO PAI
  • Publication number: 20240157015
    Abstract: The vehicle interior deodorizer may comprise a deodorizing device for deodorizing the interior of a vehicle and a method of using the deodorizing device. During a treatment cycle, the deodorizing device may release a chemical tablet into a cup holding water after an evacuation interval. The chemical tablet may dissolve in the water, creating a deodorizing solution. A bubbler mechanism may de-gas the deodorizing solution and may force deodorizing gas out of the deodorizing device such that the deodorizing gas may saturate the interior of the vehicle during a treatment interval. The bubbler mechanism may quiesce during a dissipation interval such that the deodorizing gas may abate. The vehicle may be opened and aired out to complete the treatment cycle.
    Type: Application
    Filed: May 5, 2023
    Publication date: May 16, 2024
    Inventors: Ryan Eade, Zach Fearnside, Mark Welker, Garrett Pell
  • Publication number: 20240157016
    Abstract: One aspect of the invention provides an air purifier with a plurality of baffles mounted adjacent a first port. The baffles are arranged in a spaced apart arrangement to provide a series of flow channels. Port guiding surfaces direct the air flowing between the flow channels and the first port and chamber guiding surfaces direct the air flowing between the flow channels and the sterilizing chamber. Another aspect of the invention provides an air purifier with a plurality of baffles mounted adjacent a second port for receiving the air flow out from the fan into the sterilizing chamber. The baffles provide a series of port guiding surfaces for directing the air flowing from the fan generating the flow through the second port, and a series of chamber guiding surfaces oriented generally in the flow direction for directing air flowing from the baffles into the sterilizing chamber.
    Type: Application
    Filed: September 25, 2023
    Publication date: May 16, 2024
    Inventor: James LOSSER
  • Publication number: 20240157017
    Abstract: Described is a medical dressing that includes a substrate. The dressing has a bacteriostatic composition integrated in the substrate or being provided as a coating on a surface of the substrate. The bacteriostatic composition can include deferiprone. Described is also a method for manufacturing a dressing and to the use of the medical dressing in preventing bacterial infections.
    Type: Application
    Filed: April 21, 2022
    Publication date: May 16, 2024
    Inventors: Marina Craig, Goran Edenro, Eric Wellner, Milja Elias, Sofia Almqvist
  • Publication number: 20240157018
    Abstract: An absorbent article 100 includes an absorber 10, the absorber 10 contains water-absorbent resin particle 10a composed of a deodorant composition, and the deodorant composition contains silver zeolite, an organic antimicrobial, and a water-absorbent resin.
    Type: Application
    Filed: October 14, 2020
    Publication date: May 16, 2024
    Inventors: Masashi TAKEMURA, Moe NISHIDA
  • Publication number: 20240157019
    Abstract: A system for managing female incontinence includes a body of biocompatible material configured to fit between the labia minora and the vestibule floor, the body having a surface configured to occlude the urethral meatus, an adhesive carried on at least a first portion of the surface and configured to provide a sealing engagement between the body and the urethral meatus, and a substance carried by at least one of the body and the adhesive and configured for controlling the odor of the general vaginal-urethral area of a female.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 16, 2024
    Inventors: Thomas J. Berryman, John M. Taylor
  • Publication number: 20240157020
    Abstract: The invention relates to a suture thread material comprising at least one polymer and at least one eutectic mixture. The polymer can be a biocompatible polymer such as polycaprolactone or PLGA. The eutectic mixture may comprise maleic acid and an antibiotic such as metronidazole. Other eutectic mixtures can be used in suture thread materials to reduce SSis and/or to decrease pain and/or to increase lubricity of sutures. The invention also provides a method for the production of sutures with drug loadings, the method comprising the use of therapeutic deep eutectic solvent (THEDES) technology to significantly increase drug content in suture matrices.
    Type: Application
    Filed: March 15, 2022
    Publication date: May 16, 2024
    Inventors: Shu LI, Gavin P. ANDREWS, David S. JONES
  • Publication number: 20240157021
    Abstract: The subject matter of the present invention is incorporating nanostructured antimicrobial silver perovskite particles into bone cement made of Poly Methyl Methacrylate (PMMA). This is accomplished by mixing the nanostructured antimicrobial particles with the cement powder prior to the addition of liquid monomer. The spontaneous and dispersion of the antimicrobial particles in the cement during preparation allows using a small weight for weight ratio of antimicrobial particles relative to the total mass of the cement, thereby substantially preserving the antimicrobial cement's biocompatibility compared to the biocompatibility of the native cement.
    Type: Application
    Filed: June 15, 2023
    Publication date: May 16, 2024
    Inventors: Cyrus Talebqour, Houshang Darvishi Alamdari, Hossein Salimnia, Rahul Vaidya
  • Publication number: 20240157022
    Abstract: A hemostatic composition is provided. The hemostatic composition includes a hemostatically effective amount of a hemostatic agent that includes a nanoparticle and a polyphosphate polymer attached to the nanoparticle. Also provided are medical devices and methods of use to promote blood clotting.
    Type: Application
    Filed: May 31, 2023
    Publication date: May 16, 2024
    Inventors: Damien Kudela, Galen D. Stucky, Anna May-Masnou, Gary Bernard Braun, James H. Morrissey, Stephanie A. Smith
  • Publication number: 20240157023
    Abstract: Disclosed are phototunable hydrogels, compositions that include the same, and methods for using the same for treating wounds and/or injuries, for inhibiting formation of scar tissue at wound sites, for inhibiting fibrosis in subjects in need thereof, for inhibiting lung fibrosis and/or scarring in subject in need thereof, for inhibiting formation of myofibroblasts from fibroblasts, and for inhibiting expression of ?-smooth muscle actin (?-SMA) and/or type I collagen in fibroblasts.
    Type: Application
    Filed: February 17, 2022
    Publication date: May 16, 2024
    Applicant: University of Virginia Patent Foundation
    Inventors: Steven R. Caliari, Erica Hui, Thomas H. Barker
  • Publication number: 20240157024
    Abstract: This disclosure generally relates to a ceramic scaffold. This disclosure particularly relates to a ceramic scaffold useful for bone regenerations. This disclosure also relates to a ceramic scaffold comprising hydroxyapatite (HA), tricalcium phosphate (TCP), or a mixture thereof. This disclosure also relates to a ceramic scaffold with high mechanical strength and flexibility. This disclosure further relates to a ceramic scaffold manufactured through a three-dimensional (3D) printing process, methods of manufacturing a ceramic scaffold and methods of replacing bone in a subject using the ceramic scaffold.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 16, 2024
    Inventors: Xiangjia Li, Yong Chen, Yang Chai
  • Publication number: 20240157025
    Abstract: Disclosed herein are a biodegradable polymer microparticle for a filler, a freeze-dried body including the same, a manufacturing method thereof, and filler injection including the freeze-dried body. The freeze-dried body includes hydrophilic surface-treated biodegradable polymer microparticle and a biocompatible carrier, wherein the hydrophilic surface-treated biodegradable polymer microparticle has an average particle diameter (D50) of 20 to 50 ?m and is polydioxanone which has a carboxyl group on the surface thereof. The hydrophilic surface-treated biodegradable polymer microparticle is a plasma surface-treated product or a base surface-treated product using discharge of the biodegradable polymer microparticle. The content of the biocompatible carrier is 1 to 5 parts by weight based on 100 parts by weight of the freeze-dried body.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 16, 2024
    Applicant: ULTRA V CO., LTD.
    Inventors: Cheong Cheon LEE, Lia PRISCILLA, Min Seok KWAK, Jung Woo HAN, Jung Ryul HAM, Han Jin KWON
  • Publication number: 20240157026
    Abstract: Methods, compositions and apparatus for coating bone material particles (e.g., fibers) are provided. The methods, compositions and apparatus comprise providing a container configured to receive a mineral coating liquid and a plurality of bone material particles (e.g., fibers) therein; adding the plurality of bone material particles (e.g., fibers) to the container; and contacting the plurality of bone material particles (e.g., fibers) with the mineral coating liquid in the container so as to coat each individual bone material particle (e.g., fiber) with the mineral coating liquid to form a plurality of coated bone material particles (e.g., fibers).
    Type: Application
    Filed: November 16, 2022
    Publication date: May 16, 2024
    Applicant: Warsaw Orthopedic, Inc.
    Inventor: Leenaporn Jongpaiboonkit
  • Publication number: 20240157027
    Abstract: An object of the present invention is to provide a coated medical device allowed to have not only properties such as sufficient hydrophilicity but also a bacteria adhesion inhibiting capability, and to provide a simple method of manufacturing the device. The present invention provides a coated medical device and a method of manufacturing the same, the coated medical device including a medical device and a hydrophilic polymer layer coating the surface of the medical device; wherein the hydrophilic polymer layer contains a hydrophilic polymer A, the hydrophilic polymer A containing, as monomer units, a compound a1 having a quaternary ammonium cation group and a compound a2 having a specific structure; and wherein the copolymerization ratio of the compound a1 to the compound a2 is 6/94 to 94/6.
    Type: Application
    Filed: February 4, 2022
    Publication date: May 16, 2024
    Applicant: TORAY Industries, Inc.
    Inventors: Rumiko KITAGAWA, Masataka NAKAMURA
  • Publication number: 20240157028
    Abstract: Provided is a technology that can provide an excellent suppressive effect against adhesion of calculi or calcification in a medical device to be retained within the body. This agent for suppressing calculi adhesion or calcification contains polydopamine and/or a derivative thereof, and is used to form at least an outermost surface of a coating layer of a medical device to be retained within a urinary organ or a circulatory organ.
    Type: Application
    Filed: February 15, 2022
    Publication date: May 16, 2024
    Inventors: Katsumi SHIGEMURA, Hideto MATSUYAMA, Kazuo KUMAGAI, Youngmin YANG
  • Publication number: 20240157029
    Abstract: A method includes covering or contacting a portion of a parathyroid of a subject with a shield including biologic tissue. The covering or contacting occurs during a neck or reconstructive surgery of the subject.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Inventor: James Glenn Norman
  • Publication number: 20240157030
    Abstract: An interpenetrating polymer network (IPN) structured hydrogel includes a crosslinked first natural polymer macromer with a first elasticity and an interpenetrating network of crosslinked second natural polymer macromers having a second elasticity higher than the first elasticity, the IPN structured hydrogel being cytocompatible, and, upon degradation, produce substantially non-toxic products.
    Type: Application
    Filed: September 19, 2023
    Publication date: May 16, 2024
    Inventor: Eben Alsberg
  • Publication number: 20240157031
    Abstract: A medical device that includes a titanium metal coating and/or a titanium nitride coating, and an optional titanium oxide coating.
    Type: Application
    Filed: January 19, 2024
    Publication date: May 16, 2024
    Inventors: Jay Yadav, Noah Roth, Jordan Bauman
  • Publication number: 20240157032
    Abstract: A high-strength medical fiber composite material includes a sodium alginate hydrogel matrix and a fiber framework. The fiber framework is completely embedded in the sodium alginate hydrogel matrix and formed by compounding supporting layer fibers and reinforcing layer fibers. The reinforcing layer fibers are located above the supporting layer fibers. The reinforcing layer fibers and the supporting layer fibers are orthogonal to each other. According to the high-strength medical fiber composite material prepared in the present invention, the stiffness is improved by 3-4 orders of magnitude, the tensile strength is improved by 2-3 orders of magnitude, and the high-strength medical fiber composite material has high biocompatibility and safety and a great application prospect.
    Type: Application
    Filed: November 29, 2021
    Publication date: May 16, 2024
    Applicant: CHANGZHOU INSTITUTE OF TECHNOLOGY
    Inventors: Che ZHAO, Songxue LIU, Chun FENG, Zhiwei WU, Yiwei ZHANG, Wenbiao JIANG, Xiaozhen LI
  • Publication number: 20240157033
    Abstract: A system for altering blood flowrate during donation comprising a height adjustable blood collection assembly including: a base, a tower extending upward from the base, an actuator and a carrier; the actuator is coupled to the carrier and the tower, and the actuator vertically adjusts the carrier relative to the base; a receptacle being connected to the carrier and configured to receive a blood collection container; and a controller that interacts with at least the actuator.
    Type: Application
    Filed: November 8, 2023
    Publication date: May 16, 2024
    Inventors: James G Madsen, Kyungyoon Min, Thomas Gniadek
  • Publication number: 20240157034
    Abstract: An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing. After autotransfusion processing, the centrifuge bowl and fluid line organizer are easily and efficiently decoupled from the centrifuge housing and discarded.
    Type: Application
    Filed: January 23, 2024
    Publication date: May 16, 2024
    Applicant: Sorin Group Italia S.r.l.
    Inventors: Andrea Galavotti, Elisa Maculan, Giampaolo Simonini, Iva Panzani
  • Publication number: 20240157035
    Abstract: A system and method for splitting a fluid into fluid products with a component count within a designated component count range and volume within a designated volume range. The method includes measuring an initial component concentration of a source container, weighing a source container to determine the volume of fluid, calculating the final component count and final volume for each of the source and at least one satellite container, calculating the amount of component additive solution to add the source container and flowing the amount of component additive solution from a component additive solution container into the source container, and splitting the fluid so that each divided fluid amount has a final component count within a designated component count range and a final volume within a designated volume range.
    Type: Application
    Filed: November 7, 2023
    Publication date: May 16, 2024
    Inventors: James Madsen, Kyungyoon Min
  • Publication number: 20240157036
    Abstract: A fluid handling cassette, such as that useable with an automated peritoneal dialysis (APD) cycler device or other infusion apparatus, may include a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for a fluid that includes a channel. A patient line port may be arranged for connection to a patient line and be in fluid communication with the at least one pump chamber via at least a first one of said flowpaths, and an optional membrane may be attached to the first side of the body over the at least one pump chamber. In one embodiment, the membrane may have a pump chamber portion with an unstressed shape that generally conforms to the depression of the at least one pump chamber in the body and is arranged to be movable for movement of the fluid in a useable space of the at least one pump chamber.
    Type: Application
    Filed: November 16, 2023
    Publication date: May 16, 2024
    Applicant: DEKA Products Limited Partnership
    Inventors: David W. McGill, James D. Dale, Simon C. Helmore, Richard J. Lanigan, Jason A. Demers, Dean Kamen
  • Publication number: 20240157037
    Abstract: A blood purification apparatus configured such that the connection of a chamber member is prevented from being forgotten when blood purification treatment is performed after the switching to a single-needle state. A blood purification apparatus is arbitrarily switchable between a double-needle state and a single-needle state and includes a blood pump 4, a delivery-amount-detecting unit 11 configured to detect the amount of liquid delivery made with the operation of the blood pump 4, a pressure detector 6 configured to detect the pressure in a blood circuit, a chamber member 9 connected to an air-trap chamber 5 in the single-needle state and configured to receive and store the blood in the blood circuit in a blood-collection phase in which blood is collected from the patient and to discharge the stored blood into the blood circuit in a blood-return phase in which the blood is returned to the patient.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Applicant: NIKKISO COMPANY LIMITED
    Inventors: Syu TASHIRO, Tomohiro SUZUKI
  • Publication number: 20240157038
    Abstract: A blood processing device includes a pump system, a valve system, a centrifuge, and a controller configured and/or programmed to control the operation of the pump system, the valve system, and the centrifuge to execute a blood separation procedure. The blood separation procedure executed by the controller includes pumping blood into the centrifuge, separating the blood in the centrifuge into red blood cells and plasma, and collecting portions of the separated red blood cells and plasma. Subsequently, a portion of the collected red blood cells is pumped back into the centrifuge to collect an additional amount of the separated plasma. A buffy coat or white blood cell layer may be formed between the separated red blood cells and plasma in the centrifuge. If so, a portion of the collected plasma may be pumped back into the centrifuge to harvest the buffy coat or white blood cell layer.
    Type: Application
    Filed: November 13, 2023
    Publication date: May 16, 2024
    Inventors: Benjamin E. Kusters, Richard I. Brown, Kyungyoon Min
  • Publication number: 20240157039
    Abstract: The present disclosure includes methods, apparatuses, and systems for aspirating the airway of a patient. The apparatus includes a main body having a pump and a storage cannister housing coupled to the main body and containing a storage container that is at least partially collapsible. In some configurations, the main body can include a pressure sensor, a controller in communication with the pressure sensor, and having a processor, a memory, and a power source in communication with the controller. The storage cannister housing can include a first end coupled to the main body, and a second end having a weighted portion and configured to be coupled to the first end to permit free rotation, such that the second end gravitationally rotates.
    Type: Application
    Filed: November 8, 2023
    Publication date: May 16, 2024
    Inventors: R. Lyle Hood, Robert De Lorenzo, Tyler Bull, Saketh Ram Peri, Alejandro Medina-Montemayor, Zach Fallon
  • Publication number: 20240157040
    Abstract: An enema assist device is provided. The device includes a support and the support is configured to be placed on a toilet bowl such that the support front is oriented towards the front of the toilet bowl. The support is configured to support a fluid delivery tip such that the fluid delivery tip is disposed on the top surface of the support and protrudes at least partially beyond a plane defined by a top of the toilet seat.
    Type: Application
    Filed: March 22, 2022
    Publication date: May 16, 2024
    Applicant: The Children's Hospital of Philadelphia
    Inventors: Joy Kerr, Michelle Hsia, Jason Van Batavia
  • Publication number: 20240157041
    Abstract: Disclosed herein are systems for aspirating, irrigating, and/or mechanically disrupting body cavities, such as abdominal abscesses, empyemas, and/or (e.g., complicated) pleural effusions, and associated devices and methods. In some embodiments, an aspiration and irrigation system includes an inner catheter defining an aspiration lumen and an outer tube positioned coaxially around the inner catheter and defining an irrigation lumen. A distal portion of the outer tube can be bonded to the inner catheter, and a plurality of apertures can be formed through the outer tube proximal of the bond. The aspiration lumen can be fluidly coupled to an aspiration circuit configured to aspirate through the aspiration lumen, and the irrigation lumen can be fluidly coupled to an irrigation circuit configured to flow an irrigation fluid through the irrigation lumen and out of the apertures.
    Type: Application
    Filed: November 10, 2023
    Publication date: May 16, 2024
    Inventors: Christopher Andrew Zikry, Steven McConnell
  • Publication number: 20240157042
    Abstract: A patient may be connected to a variety of medical equipment which may vary patient to patient or during the patient's treatment. Similarly, other user may wish to have configurable workstations, configurable desks, configurable displays, configurable furniture etc. where in each instance, both medical and non-medical, the system should not only provide mounting and support but also ease of mobility. The invention provides a pole support system with attended attachments allowing a diverse range of equipment, supports, shelves, electrical equipment etc. to be mounted and supported upon a mobile base in a highly configurable manner. Further, a user can easily move and position some elements upon the pole support system with only one hand as their other hand is engaged holding something else.
    Type: Application
    Filed: March 3, 2022
    Publication date: May 16, 2024
    Inventors: MARK SUNDERLAND, GAIL SNUGGS
  • Publication number: 20240157043
    Abstract: A patient care system is configured for infusing fluid to a patient. The system includes a plurality of modular fluid infusion pumps that each has a connector for connecting to a modular programming unit or to one another. Systems and methods are configured for verifying that the connectors are reliably performing their functions or communicatively connecting the pumps to one another or to the programming unit.
    Type: Application
    Filed: November 21, 2023
    Publication date: May 16, 2024
    Inventor: Andre Gamelin
  • Publication number: 20240157044
    Abstract: One or more examples may include a system. Such a system may include a cartridge, a pneumatic drive system, a position detector, and a controller. The cartridge may include a piston configured to move within a holding chamber of the cartridge and urge medicine toward an interface between the holding chamber and a region external to the cartridge. The pneumatic drive system may be configured to actuate movement of the piston within the holding chamber. The position detector may be configured to generate information about a position of the piston within the holding chamber. The controller may be configured to vent working fluid from the pneumatic drive system at least partially responsive to information about the position of the piston within the holding chamber generated by the position detector.
    Type: Application
    Filed: November 14, 2023
    Publication date: May 16, 2024
    Inventor: Peter Kimball
  • Publication number: 20240157045
    Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pressurized gas source, and a casing (9) enclosing therein the drug container, the pressurized gas source and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the drug container being contained within a container receiving cavity (75) of a container casing portion (38) of the casing (9) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pressurized gas source in a gas tight manner, the pressurized gas source configured to supply pressurized gas in the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of the liquid drug.
    Type: Application
    Filed: March 8, 2022
    Publication date: May 16, 2024
    Inventors: PEER KOSTAL, MATTHIAS MÜLLER
  • Publication number: 20240157046
    Abstract: Devices for protecting a user from a sharp tip of a medical needle includes a central body portion, a medical needle having a sharp tip, a pair of wings in attachment to the central body portion. The medical needle includes a longitudinal axis that is substantially perpendicular to at least one of a long axis of the central body portion and the delivery tube. The pair of wings are selectively positionable in a first position in which the pair of wings are spaced apart from the medical needle and a second position in which the pair of wings are proximate the medical needle. A mechanical fastener is disposed on at least one of the pair of wings, the mechanical fastener configured to selectively attach the pair of wings together in the second position with the medical needle positioned therebetween. Methods of using the device including administering medicinal fluids.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Inventor: Paul LAMBERT
  • Publication number: 20240157047
    Abstract: An infusion adapter for connection with an infusion fluid container includes a connection portion configured to engage an injection port of an infusion fluid container, and a port configured to connect to an intravenous line, with the port in fluid communication with the connection portion. The connection portion includes a retaining ring extending radially outward from the connection portion, with the retaining ring configured to securely connect the infusion adapter to the infusion fluid container to substantially prevent disconnection of the infusion adapter from the infusion fluid container once the infusion adapter is connected to the infusion fluid container. The retaining ring includes an indicator configured to provide visualization of insertion of the connection portion into an injection port of an infusion fluid container.
    Type: Application
    Filed: January 19, 2024
    Publication date: May 16, 2024
    Inventors: Yan Yevmenenko, Andrew Wong, Brent Huber
  • Publication number: 20240157048
    Abstract: An intravenous (IV) spike for administering a medicinal fluid from a container may include a head portion at a proximal end thereof, a base portion at a distal end thereof, and an elongate body portion connecting the head and the base portions. The elongate body portion may be configured to be coupled to the container. The IV spike may further include a radial notch extending at least partially along a circumference of an outer surface of the elongate body portion. The radial notch may be recessed radially inward from the outer surface.
    Type: Application
    Filed: January 23, 2024
    Publication date: May 16, 2024
    Inventors: Benjamin Yang Teck TAN, Mum Pew NG
  • Publication number: 20240157049
    Abstract: Infusion control devices are disclosed that can actively control and monitor medical fluid administration for gravity based infusion of medical fluid, where the gravity infusion control system is couplable with an intravenous administration set and can include a flow monitor, a flow controller, and a user interface.
    Type: Application
    Filed: November 8, 2023
    Publication date: May 16, 2024
    Inventors: Aravinthkumar GANESAN, Dinesh VATTIPALLI
  • Publication number: 20240157050
    Abstract: The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.
    Type: Application
    Filed: November 20, 2023
    Publication date: May 16, 2024
    Inventors: Donald Halbert, Jesse Guerra, Stephen Bollish
  • Publication number: 20240157051
    Abstract: A method for controlling a fluid-flow sensor in the presence of a flowing fluid, the method comprising: applying an electrical bias to the heater element of the fluid-flow sensor, determining a phase of the flowing fluid, and modifying the electrical bias according to the phase of the flowing fluid. A controller for a fluid-flow sensor is also described.
    Type: Application
    Filed: February 10, 2023
    Publication date: May 16, 2024
    Applicant: Flusso Limited
    Inventors: Chris Rosser, Jon Callan
  • Publication number: 20240157052
    Abstract: Apparatuses and methods for transitioning to sleep mode or otherwise modified glucose target range in automated insulin delivery systems. For example, sleep mode can include a lower glucose target and/or lower and narrower glucose target range because of fewer variables that affect glucose values during sleep such as eating and exercise. Due to increased stability provided by the sleep mode target range, it is desirable to transition to the sleep mode target range as quickly as possible, while ensuring the transition is done safely and does not risk low glucose or hypoglycemia by too quickly switching to the lower and narrower target range. Systems and methods disclosed herein therefore provide various approaches for safely and quickly transitioning to sleep mode or other modified target ranges in order to improve time in range by being more aggressive to get to the lower sleep mode or other target faster without risking hypoglycemia.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Inventors: Alexandra Elena Constantin, Michael Michaud, Geoffrey A. Kruse, Thomas R. Ulrich, Paul Harris, Virginia S. Lu, Garrett Marin
  • Publication number: 20240157053
    Abstract: Invasive glucose sensors and noninvasive glucose sensors may be used in conjunction to improve glucose management for a user. The rate of change (ROC) of glucose levels from a noninvasive glucose sensor may be used rather than or in conjunction with a glucose level of the user from a CGM. A basal insulin delivery rate to the user may be adjusted responsive to the ROC glucose level data from the noninvasive sensor. The glucose level ROC from a noninvasive glucose sensor may be used to predict future glucose level ROCs of the user between operational cycles of an insulin delivery device and/or to identify possible hypoglycemic or hyperglycemic events. These predicted future glucose level ROCs may be used in a cost function of the control system of the insulin delivery device to select basal insulin delivery doses. Glucose level readings may be used to calibrate a noninvasive glucose level sensor.
    Type: Application
    Filed: October 31, 2023
    Publication date: May 16, 2024
    Inventors: Joon Bok LEE, John D’ARCO, Yibin ZHENG, Jason O’CONNOR, James CAUSEY, Ashutosh ZADE
  • Publication number: 20240157054
    Abstract: A method, system, and computer-readable medium are provided for an Automated Insulin Delivery (AID) system in which Model Predictive Control (MPC) thereof implements weighting of glucose target error relative to corresponding predicted blood glucose (BG) levels according to insulin on board (IOB). Accordingly, basal insulin infusion and available additional bolusing each in connection with glycemic disturbances such as unannounced meals can be proximally administered to maintain time in range (TIR) without incurring insulin stacking.
    Type: Application
    Filed: November 13, 2023
    Publication date: May 16, 2024
    Inventors: Marcela MOSCOSO-VASQUEZ, Jose GARCIA-TIRADO, Patricio COLMEGNA, Marc D. BRETON
  • Publication number: 20240157055
    Abstract: A drug delivery system including a memory storing programming code operable to enable delivery of insulin and a processor operable to execute the programming code. When executed, the programming code causes the processor to: calculate a first aggregate insulin-on-board amount for a user based on a plurality of individual insulin-on-board estimates made over a first period of time, determine that the first aggregate insulin-on-board amount is greater than a maximum depot formation threshold amount, determine a first residual amount of insulin remaining in the first aggregate insulin-on-board amount, increase a subsequent calculation of an individual insulin-on-board estimate based on the first residual amount of insulin, and utilize the subsequent calculation of the individual insulin-on-board estimate in a calculation of a second aggregate insulin-on-board amount over a second period of time.
    Type: Application
    Filed: November 14, 2023
    Publication date: May 16, 2024
    Inventors: Joon Bok LEE, Yibin ZHENG, Jason O'CONNOR, Ashutosh ZADE
  • Publication number: 20240157056
    Abstract: In some embodiments, an adjunct device for tracks time and/or dosage of a medicine. The device may include a connector for mounting the device to a deposable pen injector. The device may be configured to allow use of the native controls and injectors of the injector. For example the device may include a view port for viewing a dose indicator of the injector. The device may include one or more vibration sensors. A processor may be configured to differentiate increasing a dose, decreasing a dose and/or discharging the medicine based on the output of the sensors. Optionally a display of the device may be positioned for simultaneous viewing with the dosage indicator of the injector. For example a user may verify the accuracy of the adjunct device before performing a discharge.
    Type: Application
    Filed: December 20, 2023
    Publication date: May 16, 2024
    Applicant: G. E. Ehrlich (1995) Ltd.
    Inventor: Menash MICHAEL
  • Publication number: 20240157057
    Abstract: A real-time drug injection time duration measurement system includes a sound transducer, a waveform shaping circuit operably coupled therewith, a pulse clamping circuit operably coupled with the waveform shaping circuit, and a timer operably coupled with the pulse clamping circuit. The sound transducer detects a first sound associated with drug delivery initiation and a second sound associated with drug delivery completion and is further converts the detected first and second sounds into a first electronic waveform and a second electronic waveform, respectively. The waveform shaping circuit converts the first and second waveforms into a first pulse and a second pulse, respectively. The pulse clamping circuit triggers upon receiving the first pulse and generate a regenerated pulse. The timer initiates upon receiving the regenerated pulse and stop upon receiving a subsequent regenerated pulse via the pulse clamping circuit.
    Type: Application
    Filed: March 28, 2022
    Publication date: May 16, 2024
    Applicant: AMGEN INC.
    Inventors: Huixing Jin, Julian JAZAYERI, Sergio Giovanni VALENZUELA, Ryan David SELVE, Sivakumar PARAMANANDAM
  • Publication number: 20240157058
    Abstract: The present disclosure is directed to threaded plunger syringes with tactile feedback mechanisms and method of using such syringes. The syringes can include a first configuration, wherein the threads of the threaded plunger are engaged by the syringe such that fluid delivery can be precisely controlled, and a second configuration, wherein the threads of the threaded plunger are not engaged such that the syringe can act similar to that of a conventional plunger syringe. In addition, the syringes can include a tactile feedback mechanism that provides tactile feedback when a predetermined amount of fluid volume is dispersed.
    Type: Application
    Filed: October 16, 2023
    Publication date: May 16, 2024
    Applicant: Aspen Neuroscience, Inc.
    Inventor: Edward D. WIRTH
  • Publication number: 20240157059
    Abstract: Provided herein are devices useful in processing fat for fat grafting and for delivering fat tissue grafts to a patient. Also provided are devices and methods for fat grafting and for treatment of plantar fasciitis.
    Type: Application
    Filed: January 22, 2024
    Publication date: May 16, 2024
    Inventors: Jeffrey A. Gusenoff, Beth R. Gusenoff