Abstract: Systems, devices, and methods for detaching an implantable device from a delivery system are disclosed herein. One aspect of the present technology, for example, is directed toward an elongated shaft having an inner surface that defines a lumen that extends distally from the proximal portion to an opening at a distal terminus of a distal portion. In some embodiments the distal portion includes an inner polymer structure having a first portion and a second portion positioned distal of the first portion along the length of the inner polymer structure. The first portion can have a first stiffness and the second portion can have a second stiffness less than the first stiffness. The distal portion can further include an outer polymer structure disposed around the inner polymer structure and a coil wound around the inner polymer structure and disposed within the outer polymer structure.

Abstract: An extension guide catheter (1) for a guide catheter, comprising: a tubular body (2) with a lumen (3) extending in a longitudinal axis direction; and a linear member (12) extending proximally from the tubular body (2); wherein an annular or helical groove (7) extending in a circumferential direction is formed on an inner surface of a distal end portion (6) of the tubular body (2), and wall thickness of the tubular body (2) is formed thin at a part where the groove (7) is formed.

Abstract: A delivery system for the deployment of an implant includes a delivery catheter, a tissue penetrating element disposed on an open distal end of the delivery catheter, and a guard member comprising a proximal portion disposed over, and translatable relative to, the respective tissue penetrating element and distal end of the delivery catheter, the guard member defining a lumen configured to receive and cover the tissue penetrating element, the lumen defining a longitudinal axis of the guard member, wherein the proximal portion of the guard member transitions into a split-open distal portion adjacent a distal opening of the lumen, the split-open distal portion comprising a contour configured to engage and deflect the tissue penetrating element at an angle relative to the longitudinal axis of the guard member when the guard member is translated proximally relative to the tissue penetrating element.

Abstract: A system, apparatus and method directed to placing a medical instrument in a vasculature of a patient body, the system including an optical fiber with one or more core fibers. The system can include a console having non-transitory computer-readable medium storing logic that, when executed, causes operations of providing an incident light signal to the optical fiber, receiving a reflected light signal of the incident light, wherein the reflected light signal is reflected from at least one of red blood cells or tissue within the patient body, processing the reflected light signal to determine an oxygen level within the patient body near a distal tip of the optical fiber. The method can include determining a location of the distal tip of the optical fiber within the patient body at least based on the oxygen level.

Abstract: Provided herein is an instrument delivery device for use with an intravenous catheter assembly. The instrument delivery device includes a housing having a proximal end portion and a distal end portion and defining an inner volume, an instrument movably received within the inner volume, a coupling device positioned at the distal end portion of the housing and configured to couple the housing to an access connector of an intravenous catheter assembly, an advancement member configured to move relative to the housing to advance a distal end of the instrument beyond the distal end portion of the housing and into the intravenous catheter assembly, and a light generating element disposed at least partially within the housing and configured to generate light that enables visualization of the instrument.

Abstract: A medical apparatus includes a bending medical device including a bendable body and a base part on which the bendable body is disposed, and a support base including a moving stage configured to support the bending medical device in a detachably attachable manner and a support unit configured to support the moving stage so as to be movable linearly in a predetermined direction, wherein the moving stage supports the bending medical device so as to be movable linearly in the predetermined direction.

Abstract: A deflectable catheter is provided with a sheath having a bendable section, a first traction wire and a second traction wire anchored to the bendable section of the sheath, and a driving mechanism configured to pull and release the first/second traction wire, wherein when the driving mechanism pulls either of the first traction wire and the second traction wire to bend the sheath towards the side of the pulled traction wire, the other traction wire is correspondingly released, so that the sheath is bidirectionally bendable at its bendable section in at least two directions of the sheath. In this way, the requirements for interventional treatment of complex lesion sites with vascular distortion and varied vascular opening positions may be fully met, and the frequency of catheter adjustments and replacements by clinical operators can be greatly reduced, thereby facilitating the operation and reducing the risk of complications.

Abstract: A medical device, for example a delivery catheter, may include a handle portion, a shaft portion extending distally from the handle portion, a deployment mechanism, and an actuation member positioned on the handle portion. The shaft portion may include a working channel and a distal tip portion having a payload chamber configured to receive a payload, such as a bio-absorbable foam. The distal tip portion may be operatively connected to the working channel. The deployment mechanism may be positioned in the working channel, and may be operable to deploy the payload out from the distal tip portion. The actuation member may be actuatable to operate the deployment mechanism.

Abstract: A securement device (100) for a catheter assembly (10) includes a base (102) having a first major surface (104) and an opposing second major surface (106). The base (102) defines a through cavity (108). The base (102) is detachably secured to a skin (12) of a user, such that an injection site (22) associated with the catheter assembly is disposed within the through cavity (108). The through cavity (108) receives at least a portion of the catheter assembly (10) therein. The securement device (100) also includes a casing (116) that encloses the through cavity (108) and the catheter assembly (100). The casing (116) engages with the catheter assembly (100) to secure the catheter assembly (100) within the through cavity (108). The casing (116) includes a material having a self-healing property. The casing (116) at least partially ruptures to receive at least one lumen (18) of the catheter assembly (100) therethrough.

Abstract: An apparatus for wrist and catheter stabilization during radial artery access includes a wrist support member and a catheter support member connected by an adjustable coupler. The wrist support member comprises a first platform with a curved surface configured to cradle a wrist in a supine or neutral position and an inclined portion to motivate extension or ulnar flexion of the wrist. The catheter support member comprises a second platform with a curved sidewall extending along at least one side of the second platform. The curved sidewall may be configured to direct a catheter toward a radial access point of the wrist when the catheter is extended across the platform portion of the catheter support member. The adjustable coupler is reconfigurable to control a height of the catheter support member from the wrist support member, as well as orientation and other height/distance parameters in some embodiments.

Abstract: A guide catheter extension, having a push member having a proximal end and a distal end; a tube frame coupled to the distal end of the push member, the tube frame defining a lumen having a diameter sufficient to receive an interventional vascular device therethrough; and an inflatable element coupled to the tube frame, wherein the inflatable element is expandable into the lumen.

Abstract: An insertion tool for inserting a catheter into a patient's body is disclosed. The insertion tool unifies needle insertion, guidewire advancement, and catheter insertion in a single device. In one embodiment, the insertion tool comprises a housing in which at least a portion of the catheter is initially disposed, a hollow needle distally extending from the housing with at least a portion of the catheter pre-disposed over the needle, and a guidewire pre-disposed within the needle. A guidewire advancement assembly is also included for selectively advancing the guidewire distally past a distal end of the needle in preparation for distal advancement of the catheter. A catheter advancement assembly is also included for selectively advancing the catheter into the patient. The catheter advancement assembly includes a mechanical advantage mechanism coupled between the slide of the insertion tool and the catheter.

Abstract: A catheter system may include a catheter assembly and a needle safety clip disposed within a safety can proximal to the catheter assembly. The catheter system may include a barrel, a needle hub fixed to the barrel, an introducer needle secured within the needle hub, a catheter hub slider, a guidewire slider, and a guidewire coupled to the guidewire slider. In response to the movement of the catheter system from a first position to a second position, the guidewire slider may push out on a flexible arm of catheter hub slider such that the flexible arm is removed from contact with the needle hub, and the catheter hub slider is configured to slide from a catheter hub slider proximal position to a distally-advanced position.

Abstract: A catheter system may include a catheter assembly, which may include a catheter hub and a catheter. The catheter system may include a barrel, a clip and needle hub disposed within the barrel, an introducer needle secured within the needle hub, and a catheter hub slider extending through a slot of the barrel and configured to slide along the slot from a catheter hub slider proximal position to a distally-advanced position. The catheter system may include guidewire configured to advance distally through the introducer needle. The catheter system may include a guidewire slider extending through the slot and configured to slide along the slot from a guidewire slider proximal position to a distal position to advance the guidewire. When the guidewire slider is in the guidewire slider proximal position, the catheter hub slider may be prevented from sliding along the slot.

Abstract: A device for delivering a guidewire to a target location in a patient's body includes a hollow needle having: a lumen configured to receive the guidewire; a body section; and a biased section, the biased section configured to bend relative to the body section, the biased section located on a distal end of the hollow needle. The device includes a catheter having a catheter lumen, the catheter lumen configured to: receive the hollow needle, and maintain the biased section and the body section in relative alignment in a first configuration. The hollow needle, in response to the biased section extending out from the catheter, is configured to bend the biased section relative to the body section in a second configuration.

Abstract: A shunt is described that expands to an hourglass shape. As the shunt expands, both of its ends radially flare outwards relative to its middle section and the length of the shunt foreshortens, which causes the flared ends to engage the tissue surrounding a puncture or aperture within a patient's tissue.

Abstract: A ureteral stent includes a metal stent and a tubular membrane, the metal stent includes a plurality of unit sections. The application further discloses a testing device, which includes a silicone hose, an outer hard tube, a ureteral stent, a pressure mechanism, a flow mechanism, a flow rate mechanism, a rotation mechanism; the pressure mechanism is connected with the space between the silicone hose and outer hard tube, and the pressure in the pressure mechanism can enable the silicone hose to expand or contract; the flow mechanism can change the speed of the water pump with the frequency converter to adjust the flow rate of liquid in the silicone hose, and the flow rate mechanism can change the shape of the silicone hose to adjust the flow rate of liquid in silicone hose.

Abstract: A medical device may include a handle and an end cap. The handle may include a first movable body and a stationary body. The end cap may include an outer portion, an inner portion disposed within the outer portion, and at least one biasing member. The outer portion may define a receptacle configured to contain a material. The inner portion may be proximal to the receptacle, within the outer portion, and coupled to the first movable body by at least one control element. The biasing member(s) may be disposed between a proximal face of the inner portion and a distal face of a proximal wall of the outer portion. Accordingly, movement of the first movable body relative to the stationary body moves the inner portion relative to the outer portion. Movement of the inner portion may be configured to deliver the material.

Abstract: The present invention relates to a device (100) for treating a vaginal lesion, by forming a coagulated blood mass, which is introduced by the device (100) into the vagina. The device (100) comprises an elongated guiding tube (102) having a lumen (104) for receiving whole blood and a plunger (112) having a piston element (114) fitted within the lumen (104) thus defining a blood coagulating space (109) between it and a blood-introducing end (106). The guiding tube (102) is configured for being introduced into the vagina and to discharge a coagulating blood mass formed within the lumen (104), in result of displacement of the displaceable piston (114) element. The coagulated blood mass may be maintained in the vagina by an anchoring element (122) configured to expand within the vagina and maintain there for a desired time and then be retrieved. Methods of treatment are also disclosed.

Abstract: The disclosed apparatus, systems and methods relate to a permeation enhancing transdermal patch for the administration of a therapeutic compound transdermally. A transdermal patch for the administration of a therapeutic compound to a subject that has a microneedle layer with microneedles made of naloxone and a binder, an active layer with naloxone and a carrier and an augmentation layer configured to generate local heat on the skin of the subject. The patch can omit the microneedle layer or augmentation layer.

Abstract: A medical agent delivery device may comprise a collapsible reservoir and a base portion including at least one microneedle on a first face and on an opposing second face. Each microneedle on the first face may fluidically communicate with a microneedle on the second face. The device may further comprise an elastomeric housing attached to the first face. The reservoir and the at least one microneedle on the first face of the base portion may be within the elastomeric housing. The device may further comprise a displaceable spacer having a first position in which the spacer supports the reservoir in spaced relation to the at least one microneedle on the first side of the base portion. When the spacer is in a second position, the elastomeric housing may be configured to press the reservoir into the at least one microneedle on the first side of the base portion.

Abstract: A delivery device for delivery of medical agent to a barrier may comprise a main body including a central region defining a receptacle, a peripheral region defined by a number of petal members, and a set of retention tabs extending into the receptacle. The delivery device may further comprise a reservoir including at least one delivery sharp, a main interior volume, and at least one septum in fluid communication with the main interior volume. The reservoir may be coupled to the main body via the retention tabs. The delivery device may further comprise an adhesive coupled to the main body. The delivery device may further comprise at least one bias member positioned within the receptacle between the reservoir and a wall of the receptacle.

Abstract: Systems and methods for a coupling a percutaneous device. The system can include a first coupling that can be configured to connect to a first catheter extending through a percutaneous opening in a patient, a second coupling that can be configured to connect to a second catheter to fluidly connect to the first catheter, and a failure-release that can be configured to automatically disconnect the fluid connection between the first catheter and the second catheter upon the system receiving a force at or above a predetermined threshold to protect the percutaneous opening in the patient from the force.

Abstract: A female Luer fitting disinfection device comprises a container comprising a bottom surface, a side wall, and an open end; a porous foam insert disposed within the container, the porous foam insert comprising a central region. A plug is positioned within the central region, the plug sized and shaped to fit within a lumen of the female Luer fitting, and a liquid disinfectant is in the container and absorbed within the porous foam insert. A sealing web covering the open end of the container. A method of disinfecting a female Luer fitting is also provided.

Abstract: Some embodiments of the disclosure are directed to a novel system for pumping liquid such as blood without damaging cells. In some embodiments, the system includes one or more inflatable elements such as balloons which force liquid from a heart assist pump. In some embodiments, one or more pumping elements are configured to directionally inflate. In some embodiments, the heart assist pump includes a reduced cross-section between two pumping elements. In some embodiments, the reduced cross-section is configured to enable the heart assist pump to be seated in the heart using the aortic valve. In some embodiments, the reduced cross-section gives the heart assist pump and hourglass shape, which allows a greater volume of fluid to be pumped through the aortic valve. In some embodiments, a controller independently controls fluid pumping elements on either side of the reduced cross-section.

Abstract: A neuroprosthesis apparatus for stimulating leg movement in a user via functional electrical stimulation includes a waistband and a pair of leg attachment members. Each leg attachment member is coupled to and extends downwardly from the waistband. A user wears the apparatus with the waistband extending around the user's body and each leg attachment member attaching to one of the legs of the user. An electrical stimulator comprises a plurality of electrodes that is dispersed along each leg attachment member. The electrodes selectively transmit electrical current through a skin of the user to efferent nerves to induce muscle contractions and enable movement of the legs and feet of a user experiencing paralysis.

Abstract: An electrode set for making a biological tissue transparent includes a first electrode and a second electrode. The first electrode and the second electrode are configured to provide an electric field for the biological tissue. The first electrode has a carrier metal and a coating metal at least partially coated on the carrier metal.

Abstract: Presented herein are cured ring seals and related methods for at least temporarily sealing openings in fluidically-sealed body chambers. The cured ring seals include a body that is formed from a hydrophilic or hygroscopic polymer, such as polyvinyl alcohol (PVA), that is cured prior to implantation into the body of a recipient (e.g., pre-cured). The cured ring seals are substantially pliable to facilitate positioning around an outer surface of an implantable component and are configured to expand following implantation.

Abstract: Provided is a device for curing rhinitis. The device for curing rhinitis may include: a curing unit including a first insertion unit and a second insertion unit each of which is inserted into different nostrils of a user; a power equipment including a signal applying unit which supplies a driving signal to the first insertion unit and the second insertion unit; and a cable for connecting the curing unit to the power equipment, wherein the first insertion unit and the second insertion unit each include a first electrode and a second electrode which are spaced apart from each other, receive the driving signal, and provide electromagnetic wave that corresponds to the driving signal.

Abstract: The present technology is generally directed to medical implants, such as stimulation assemblies for stimulating the septal wall of the heart of a human patent, and associated methods. In some embodiments, a stimulation assembly includes a body, circuitry positioned at least partially within the body, an electrode, and an anchor coupled to the body. The anchor can be secured to the septal wall such that the body is positioned within the left ventricle of the heart and the electrode engages tissue of the septal wall. The circuitry can be configured to receive acoustic energy and to convert the acoustic energy to electrical energy, and the electrode can deliver the electrical energy to the tissue of the septal wall to stimulate the tissue.

Abstract: Catheter systems include direction-sensitive, multi-polar tip electrode assemblies for electroporation-mediated therapy, electroporation-induced primary necrosis therapy and electric field-induced apoptosis therapy, including configurations for producing narrow, linear lesions as well as distributed, wide area lesions. A monitoring system for electroporation therapy includes a mechanism for delivering electrochromic dyes to a tissue site as well as a fiber optic arrangement to optically monitor the progress of the therapy as well as to confirm success post-therapy. A fiber optic temperature sensing electrode catheter includes a tip electrode having a cavity whose inner surface is impregnated or coated with thermochromic/thermotropic material that changes color with changes in temperature. An optic fiber/detector arrangement monitors the thermochromic or thermotropic materials, acquiring a light signal and generating an output signal indicative of the spectrum of the light signal.

Abstract: Devices, systems and methods are provided to treat damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) by delivering specialized pulsed electric field (PEF) energy to target tissue areas. The energy is delivered in a manner so as to be non-thermal (i.e. below a threshold for causing thermal ablation). Consequently, when extracellular matrices present, the extracellular matrices are preserved, and the targeted tissue maintains its structural architecture including blood vessels and lymphatics. Thus, sensitive structures, such as biological lumens, blood vessels, nerves, etc, are preserved which are critical to maintaining the integrity and functionality of the tissue. The energy is delivered with the use of systems and devices advantageously designed for superior access to target tissue throughout the body, particularly in locations previously considered inaccessible to percutaneous approaches.

Abstract: Systems and methods for applying an energy means to the uterus to disrupt or suppress the electromechanical status of the uterus. In one aspect, there are provided devices and methods of delaying or suspending preterm labor or birth by applying an energy means or drugs, or other agents to the uterus to disrupt or suppress the electromechanical status or waves of the uterus and render contractions ineffective or block them entirely.

Abstract: A grip strength enhancement device according to one aspect of the present invention includes a grip motion detection unit that detects a grip motion of a user, and an electrical muscle stimulation (EMS) control unit that controls an EMS presentation unit that presents EMS to a muscle of at least one of an upper arm and a shoulder of the user, and the EMS control unit drives the EMS presentation unit to present the EMS to the muscle of at least one of the upper arm and the shoulder of the user in response to the detection of the grip motion of the user.

Abstract: Methods and apparatuses for sensory electrical stimulation of the peripheral nervous system to improve human motor function and performance are described. Methods and devices may be used to enhance physical performance of athletes, professionals, and gamers or improve motor function (hand, finger and limb movement) in patients rehabilitating from neurological deficits and impairments caused by stroke, traumatic brain injury and other neurologic or non-neurologic conditions. These apparatuses and methods may be used for physical training and mental training (to improve memory and functional performance including motor coordination, limb-eye coordination, occupational and recreational skills) through periodic or sustained sensory electrical stimulation. Treatment plans may be based on biomarkers and may be used alone or in combination with other apparatuses.

Abstract: A system for performing spinal cord stimulation on a subject is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be minimally invasively inserted to a target stimulation site within the nervous tissue, includes stimulation electrodes. The processor is configured to receive more recorded signals from the recording arrays at the target recording site, determine an electrophysiological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the determined electrophysiological state in order to affect the electrophysiological state.

Abstract: Systems and methods for planning neurostimulation programming for an autonomic condition of a patient are disclosed. A system may include a user interface device configured to provide a graphical user interface that receives patient data and outputs severity data corresponding to multiple characteristics of an autonomic condition of the patient. The system may also include a data processing system configured to: identify neural targets of the patient corresponding to respective leads and electrodes of a neurostimulation system; determine, based on the patient data, respective severity scores corresponding to the multiple characteristics of the autonomic condition; generate, using the respective severity scores, neurostimulation programming settings for use at the neural targets; and output programming data, based on the neurostimulation programming settings, for controlling neurostimulation with the neurostimulation system.

Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen provides a useful way to treat acute medical conditions. The disclosed systems and methods stimulate the neural activity of a nerve supplying a spleen, wherein the nerve is associated with a neurovascular bundle, such that the electrical signal produces an improvement in a physiological parameter indicative of treatment of an acute medical condition.

Abstract: An implantable sensor device comprising means for determining a blood pressure and means for stimulating at least one nerve cell, based at least in part on the determined blood pressure. Further aspects relate to a method carried out by such a device and a computer program.

Abstract: A system is disclosed in one example which allows for modelling the wellness of a given Implantable Pulse Generator (IPG) patient. The modelling, embodied in an algorithm, uses one or more qualitative measurements and one or more quantitative measurements taken from the patient. The algorithm correlates the qualitative measurements to the various quantitative measurements to eventually, over time, learn which quantitative measurements best correlate to the qualitative measurements provided by the patient. The algorithm can then using current quantitative measurements predict a wellness factor or score for the patient, which is preferably weighted to favor the quantitative measurements that best correlate to that patient's qualitative assessment of therapy effectiveness. Additionally, the wellness factor may be used to adjust the stimulation program that the IPG device provides to the patient.

Abstract: The present technology is directed generally to electrical stimulation and associated systems and methods for preferentially and/or selectively activating and suppressing motor neurons and/or motor responses, such as to treat a motor dysfunction in patients. For example, in some embodiments high frequency electrical stimulation can be administered to a target neural population via an implanted signal delivery device to induce a motor response in a first muscle, and low frequency electrical stimulation can be administered to the target neural population via the same signal delivery device to induce a motor response in a second muscle that is different than the first muscle.

Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.

Abstract: A leadless biostimulator includes a housing, and distal and proximal electrodes disposed on or integrated into the housing. The distal electrode includes an electrode body and an electrode tip mounted on a distal end of the electrode body, wherein the electrode tip is electrically conductive and configured to be placed in contact with a stimulation site. The electrode tip includes a distal tip end facing a surrounding environment and opposite a proximal tip end. The electrode tip defines a tip hole extending through the electrode tip along a longitudinal axis of the housing from the distal tip end to the proximal tip end. The tip hole comprises a through hole having a first diameter at the distal tip end and a second diameter at the proximal tip end of the tip electrode, wherein the first diameter of the tip hole is less than the second diameter of the tip hole.

Abstract: A pacemaker lead for cerclage pacing includes a lead fixing part including a fixing tip whose diameter becomes gradually smaller toward an end of a distal part thereof, a plurality of bipolar electrodes that come into close contact with heart muscle, in an outer circumference of the lead fixing part, and a guide wire insertion through hole through which a guide wire can be inserted thereinto, a lead body part configured to be extended to the lead fixing part, having a stylet insertion through hole formed therein, and a body fixing part formed in a bent shape so as to be fixed to an inner wall of the coronary sinus, and a stylet inserted into the stylet insertion through hole, enabling the pacemaker lead for cerclage pacing to be easily moved within the body of the patient.

Abstract: An example of a system for delivering neurostimulation may include a programming control circuit and a stimulation control circuit. The programming control circuit may be configured to generate stimulation parameters controlling delivery of the neurostimulation according to a stimulation configuration. The stimulation control circuit may be configured to specify the stimulation configuration, and may include volume definition circuitry and stimulation configuration circuitry. The volume definition circuitry may be configured to determine one or more test volumes, determine a clinical effect resulting from the one or more test volumes each being activated by the neurostimulation, and determine a target volume using the determined clinical effect. The stimulation configuration circuitry may be configured to generate the specified stimulation configuration for activating the target volume.

Abstract: A medical device system (1) and a method for operating a medical device system are de-scribed.

Abstract: Seals used within lead passageways of implantable medical devices for creating a seal to implantable medical leads inserted into the lead passageways include a body defining a lead passageway with an axial dimension. The body further defines a first circumferential protrusion extending radially a first distance into the lead passageway, and the body further defines a second circumferential protrusion separated from the first circumferential protrusion along the axial dimension. The second circumferential protrusion extends radially a second distance into the lead passageway, the second distance being less than the first distance. The body further defines a first circumferential depression immediately adjacent the first circumferential protrusion and between the first circumferential protrusion and the second circumferential protrusion.

Abstract: An AIMD includes a ceramic base closed with a ceramic lid, both cooperatively separating body fluid and device sides. The lid and circuit board both have active and conductive pathways. A circuit board has active and ground conductive pathways. An anisotropic conductive layer disposed between the lid device side and the circuit board has a first thickness where a first conductive particle is in electrical contact with the lid and the circuit board active conductive pathways electrically connected to the active terminal of an electronic component on the circuit board, a second thickness where a second conductive particle is in electrical contact with the lid and the circuit board ground conductive pathways electrically connected to the ground terminal of the electronic component. The anisotropic conductive layer has a third, greater thickness where no conductive particles are in electrical contact with the lid and circuit board conductive active and ground pathways.

Abstract: A biostimulator includes a housing having a longitudinal axis and containing an electronics compartment. The biostimulator includes a fixation element coupled to the housing. The fixation element extends about the longitudinal axis. The biostimulator includes a pacing element coupled to the housing. The pacing element includes a strain relief surrounding a flexible conductor distal to the fixation element. A stiffness of the strain relief decreases in a distal direction. Other embodiments are also described and claimed.

Abstract: An implantable device containing a plurality of batteries, the plurality of batteries including at least one first non-rechargeable battery, and at least one second rechargeable battery. A method for providing power for a Cardiac Contractility Modulation Implantable Cardioverter Defibrillator (ICD) device, the method including providing power for cardioversion or defibrillation operation by a first, non-rechargeable battery, and providing power for Cardiac Contractility Modulation operation by a second, rechargeable battery. A method for controlling power for an implantable device having a rechargeable battery, a non-rechargeable battery and a Cardioverter Defibrillator module, the method including measuring electric power level of the rechargeable battery, comparing the rechargeable battery level to a threshold, if the electric power level of the rechargeable battery is less than the threshold, then providing power for the device from the non-rechargeable battery.