Patents Issued in December 24, 2024
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Patent number: 12171542Abstract: Systems and methods for estimating quantitative histological features of a subject's tissue based on medical images of the subject are provided. For instance, quantitative histological features of a tissue are estimated by comparing medical images of the subject to a trained model that relates histological features to multiple different medical image contrast types, whether from one medical imaging modality or multiple different medical imaging modalities. In general, the trained model is generated based on medical images of ex vivo samples, in vitro samples, in vivo samples or combinations thereof, and is based on histological features extracted from those samples. A machine learning algorithm, or other suitable learning algorithm, is used to generate the trained model. The trained model is not patient-specific and thus, once generated, can be applied to any number of different individual subjects.Type: GrantFiled: July 10, 2023Date of Patent: December 24, 2024Assignee: The Medical College of Wisconsin, Inc.Inventor: Peter Sherman Laviolette
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Patent number: 12171543Abstract: A medical system includes an elongate instrument, a tracking system, and one or more processors. The tracking system is disposed along at least a portion of the elongate instrument. The one or more processors are coupled to the tracking system and are configured to: generate a plurality of linked bounded-surface elements corresponding to a set of connected passageways of a patient anatomy; receive shape information from the tracking system, the shape information indicating a shape of at least a portion of the elongate instrument when the portion is disposed in the set of connected passageways; register the shape information to the plurality of linked bounded-surface elements; and based on the registering, display a composite image including an instrument image of the elongate instrument displayed within a model of the set of connected passageways.Type: GrantFiled: June 21, 2023Date of Patent: December 24, 2024Assignee: INTUITIVE SURGICAL OPERATIONS, INC.Inventors: Vincent Duindam, Prashant Chopra
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Patent number: 12171544Abstract: The present disclosure relates to systems, computer programs, and methods employing oral cavity image capture for determining tooth displacement (e.g., for identifying patients with, or at risk for, periodontal disease). In certain embodiments, a medical imaging device or system (e.g., an intraoral scanner or other scanner) is employed to generate baseline and test scan images of at least one tooth, where the test scan is performed when the tooth in engaged with an opposing tooth in a chewing action, or is being pushed by an outside force, and the images are processed by a computer program to determine the amount of displacement of the tooth in at least one direction.Type: GrantFiled: March 20, 2020Date of Patent: December 24, 2024Assignee: The Regents of the University of MichiganInventors: Luiz Duarte Meirelles, Rafael Amorim Cavalcanti De Siqueira, Hom-Lay Wang
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Patent number: 12171545Abstract: A robotic shoe which provides real-time feedback regarding forces acting on the foot of the user, in order to modify these forces in a corrective or diagnostic manner. The shoe comprises an insole equipped with embedded pressure sensors enabling it to continuously monitor the ground reaction forces (GRF) and the foot center of pressure (COP) while the user is standing, walking, and running. The insole COP and GRF readings are input to a programmable system that shifts the COP trajectory dynamically in a patient-specific manner via the robotic platform of the shoe. The robotic platform contains motors that control elements whose movement manipulates the forces acting on the foot and lower limb, resulting in modification of the GRF. Closed loop feedback enables a dynamic fit of an optimal COP. The COP and GRF information can be stored for analysis and diagnosis of gait and instability events accruing during locomotion.Type: GrantFiled: June 1, 2020Date of Patent: December 24, 2024Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.Inventors: Alon Wolf, Hadar Shaulian
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Patent number: 12171546Abstract: The disclosed embodiments relate to a system that performs ultra-fast tracer imaging on a subject using positron emission tomography. During operation, the system performs a high-temporal-resolution, total-body dynamic PET scan on the subject as an intravenously injected radioactive tracer propagates through the vascular system of the subject to produce PET projection data. Next, the system applies an image reconstruction technique to the PET projection data to produce subsecond temporal frames, which illustrate the dynamic propagation of the radioactive tracer through the vascular system of the subject. Finally, the system outputs the temporal frames through a display device.Type: GrantFiled: July 16, 2020Date of Patent: December 24, 2024Assignee: The Regents of the University of CaliforniaInventors: Xuezhu Zhang, Jinyi Qi, Simon R. Cherry, Ramsey D. Badawi, Guobao Wang
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Patent number: 12171547Abstract: Systems and methods are provided to determine a time to provide guidance to a user regarding management of a physiologic condition such as diabetes. The determination may be based upon a model or pattern. The time to deliver guidance may be calculated to be useful to a user in the management of a glucose concentration level.Type: GrantFiled: February 6, 2019Date of Patent: December 24, 2024Assignee: Dexcom, Inc.Inventors: Alexandra Elena Constantin, Scott M. Belliveau, Naresh C. Bhavaraju, Jennifer Blackwell, Eric Cohen, Basab Dattaray, Anna Leigh Davis, Rian Draeger, Arturo Garcia, John Michael Gray, Hari Hampapuram, Nathaniel David Heintzman, Lauren Hruby Jepson, Matthew Lawrence Johnson, Apurv Ullas Kamath, Katherine Yerre Koehler, Phil Mayou, Patrick Wile McBride, Michael Robert Mensinger, Sumitaka Mikami, Andrew Attila Pal, Nicholas Polytaridis, Philip Thomas Pupa, Eli Reihman, Peter C. Simpson, Tomas C. Walker, Daniel Justin Wiedeback, Subrai Girish Pai, Matthew T. Vogel
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Patent number: 12171548Abstract: Systems, methods and apparatus are provided for determining an estimate of an analyte level over time. The invention includes sampling sensor data using an analyte sensor positioned at least partially subcutaneously; storing a plurality of datasets of sensor data, each at a different rate; determining an estimated analyte level based on the datasets; and outputting the estimated analyte level to a display. Numerous additional aspects are disclosed.Type: GrantFiled: November 13, 2020Date of Patent: December 24, 2024Assignee: ABBOTT DIABETES CARE INC.Inventor: Erwin Satrya Budiman
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Patent number: 12171549Abstract: A blood glucose measuring apparatus and a method of operating the blood glucose measuring apparatus are provided. The blood glucose measuring apparatus includes a cell capsule comprising a reservoir configured to accommodate cells in a suspension, and an electrode configured to receive electric signals from any one or both of a cell in the suspension that is not in contact with the electrode and a cell in the suspension that is in contact with the electrode, and a cell monitoring device configured to monitor the cells.Type: GrantFiled: March 12, 2021Date of Patent: December 24, 2024Assignee: Samsung Electronics Co., Ltd.Inventors: Young Jun Hong, Jonghan Kim
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Patent number: 12171550Abstract: The present invention relates to a body attachment unit for continuous glucose monitoring.Type: GrantFiled: June 7, 2019Date of Patent: December 24, 2024Assignee: I-SENS, INC.Inventors: Kyung Chul Chae, Hyun Ho Choi, Goang Yel Ryu, Ji Hoon Wang, Young Jea Kang
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Patent number: 12171551Abstract: An applicator assembly for applying at least a portion of an analyte monitor includes a frame having a longitudinal axis and an opening, a resilient member having at least a first portion fixed relative to the frame and a second portion movable axially relative to the frame, a needle, and a cap engageable with the frame to cover at least part of the opening. The cap is adjustable to increase a bias on the resilient member and to move the second portion of the resilient member away from the opening. When the cap is separated from the frame, the second portion of the resilient member is configured to be held relative to the frame. The hold on the second portion of the resilient member is releasable, such that the bias on the resilient member advances the second portion of the resilient member and the needle towards the opening.Type: GrantFiled: November 16, 2023Date of Patent: December 24, 2024Assignee: LAXMI THERAPEUTIC DEVICES, INC.Inventors: Thomas Metzmaker, Matthew Yavorsky, Michael I. Larkin, William Peter Van Antwerp, Scott Mallett, Dallin Ostler
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Patent number: 12171552Abstract: A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal into separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, calibration data from multiple calibration data sets is used to configure the demodulation of the composite signal into separate output signals.Type: GrantFiled: April 28, 2023Date of Patent: December 24, 2024Assignee: Masimo CorporationInventors: Walter M. Weber, Ammar Al-Ali, Mohamed K. Diab, Marcelo M. Lamego
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Patent number: 12171553Abstract: A sensor probe has a connector and the connector's corresponding receptacle on a console have security mechanisms that ensure that the connector and the receptacle are properly connected and mated. The connector and receptacle can have physical security features that block insertion of the connector into the receptacle if they are not aligned in a proper orientation. The console can also include a software security feature that allows optical measurements from the sensor probe only if the connector of the sensor probe and receptacle on the console are connected properly. An adapter can also be used to convert a conventional receptacle mounted on a console into a receptacle with security features.Type: GrantFiled: July 1, 2022Date of Patent: December 24, 2024Assignee: ViOptix, Inc.Inventors: Jimmy Jian-min Mao, Robert E. Lash
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Patent number: 12171554Abstract: In some examples, a medical system includes a medical device. The medical device may include a housing configured to be implanted in a target site of a patient, a light emitter configured to emit a signal configured to cause a fluorescent marker to emit a fluoresced signal into the target site, and a light detector that may be configured to detect the fluoresced signal. The medical system may include processing circuitry configured to determine a characteristic of the fluorescent marker based on the emitted signal and the fluoresced signal. The characteristic of the fluorescent marker may be indicative of a presence of a compound in the patient, and the processing circuitry may be configured to track the presence of the compound of the patient based on the characteristic of the fluorescent marker.Type: GrantFiled: September 18, 2023Date of Patent: December 24, 2024Assignee: Medtronic, Inc.Inventors: John E. Burnes, James K. Carney, Jonathan L. Kuhn, Mark J. Phelps, Jesper Svenning Kristensen, Rodolphe Katra
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Patent number: 12171555Abstract: Disclosed here are devices, systems, and methods for continuous monitoring of biomarkers using a wearable, non-intrusive microneedle sensor patch platform. In some aspects, a wearable, non-intrusive microneedle sensor device includes a microneedle sensor unit couplable to an electronics unit, where the microneedle sensor unit comprises a substrate, an array of spiked microneedle structures configured as electrochemical sensor electrodes, an array of base structures that encase a lower portion of spiked microneedle structures, and electrical interconnections that electrically couple the electrodes to the electronics unit for processing of detectable signals associated with one or multiple biomarkers in a biofluid.Type: GrantFiled: January 8, 2024Date of Patent: December 24, 2024Assignee: The Regents of the University of CaliforniaInventors: Farshad Tehrani, Joseph Wang, Hazhir Teymourian
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Patent number: 12171556Abstract: Methods, systems and devices for providing improved calibration accuracy of continuous and/or in vivo analyte monitoring systems based at least in part on insulin delivery information are provided. Many of the embodiments disclosed herein can determine appropriate conditions for performing a calibration of the analyte sensor in view of the scheduled delivery of insulin or administered insulin amount. One or more other parameters or conditions can also be incorporated to improve calibration accuracy including, for example, the physiological model associated with a patient, meal information, exercise information, activity information, disease information, historical physiological condition information, as well as other types of information. Furthermore, according to some embodiments, calibration of the analyte sensor can be delayed or not performed at all, if appropriate conditions are not met.Type: GrantFiled: January 21, 2022Date of Patent: December 24, 2024Assignee: ABBOTT DIABETES CARE INC.Inventors: Gary Alan Hayter, Erwin Satrya Budiman
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Patent number: 12171557Abstract: An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The transceiver may be configured to receive one or more measurements from the sensor. The transceiver may be configured to assess in real time a performance of the sensor based on at least the one or more measurements. The transceiver may be configured to determine whether the performance of the sensor is deficient based at least on the assessed performance of the sensor. The transceiver may be configured to calculate an analyte level based on at least the one or more sensor measurements. The transceiver may be configured to determine whether the calculated analyte level is a spike.Type: GrantFiled: July 17, 2023Date of Patent: December 24, 2024Assignee: Senseonics, IncorporatedInventors: Ravi Rastogi, James Masciotti, Xiaoxiao Chen
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Patent number: 12171558Abstract: A system and a method of performing screening tests for diagnosing a developmental condition of a human subject may include: receiving one or more profile data elements pertaining to the human subject; receiving one or more first behavioral data elements that may include information that is indicative of a behavior of a human subject from one or more data sources; analyzing the one or more first behavioral data elements in view of the one or more profile data elements to obtain a suspected impediment of development of the human subject; and presenting to the human subject a personalized test, adapted to diagnose the developmental condition of the human subject in view of the suspected impediment, to perform on a UI of a computing device according to the suspected impediment.Type: GrantFiled: March 9, 2020Date of Patent: December 24, 2024Assignee: KNOWME SOLUTIONS LTD.Inventors: Anat Burstein, Avraham Peretz
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Patent number: 12171559Abstract: An adjustment device is configured to collect estimation results of the estimated state of the occupant; determine whether or not it is necessary to check the state of the occupant on the basis of the estimation results; determine a behavior of the occupant on the basis of behavior determination information and set the state of the occupant when it is determined that it is necessary to check the state of the occupant; and output adjustment information for causing an occupant state estimating device to adjust a state estimation condition used for estimating the state of the occupant so that the estimation result of the state of the occupant becomes the set state of the occupant.Type: GrantFiled: February 3, 2021Date of Patent: December 24, 2024Assignee: MITSUBISHI ELECTRIC CORPORATIONInventor: Kento Tanaka
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Patent number: 12171560Abstract: A pixel circuit includes a sensing block, a stimulation block, a first line control circuit, and a second line control circuit. The sensing block outputs biometric data of a biosignal in response to a first selection signal. The stimulation block radiates a stimulation signal in response to a second selection signal. The first line control circuit outputs the first selection signal for selecting the sensing block as a target sensing block, and outputs the second selection signal for selecting the stimulation block as a target stimulation block. The second line control circuit processes characteristic data associated with the biometric data and the stimulation signal.Type: GrantFiled: April 20, 2020Date of Patent: December 24, 2024Assignee: Electronics and Telecommunications Research InstituteInventors: Chunwon Byun, O Eun Kwon, Chan Woo Park, Hyunkoo Lee, Sukyung Choi, Chan-Mo Kang, Byoung-Hwa Kwon, Chil Seong Ah, Hyunsu Cho, Jeong Ik Lee, Nam Sung Cho
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Patent number: 12171561Abstract: A wearable cuff based on a carrier material with an integrated signal recorder for measurements of biosignals on the skin of a living body recording at an upper arm of a human body. At least one electrode is connected to the carrier material via a reversibly compressible material. The electrodes, the base of the main circuit, and the conductors of the signal recorder are based on one and the same flexible printed circuit board (FPCB). The carrier material is an elastic material. The conductors exhibit a zig-zag, U-shape, ?-shape and/or a meandering form. The carrier material includes a woven and/or a nonwoven layer being coated with a thermoplastic polymer layer. A process to make the cuff, a process to measure biosignals on the skin of a living body, for long-term ECG recording at an upper arm of a human body, and the use of the cuff to record biosignals on the skin of a living body.Type: GrantFiled: June 24, 2019Date of Patent: December 24, 2024Assignee: Berne University of Applied SciencesInventors: Samuel Kreuzer, Tobias Bertos, Thomas Niederhauser
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Patent number: 12171562Abstract: An apparatus is provided. A strip has first and second end sections, and a first face and second face. Two electrocardiographic electrodes are provided on the strip with one of the electrocardiographic electrodes provided on the first face of the first end section of the strip and another of the electrocardiographic electrodes positioned on the first face on the second end section of the strip. A flexible circuit is mounted to the second face of the strip and includes a circuit trace electrically coupled to each of the electrocardiographic electrodes. The apparatus includes a wireless transceiver and a battery.Type: GrantFiled: August 30, 2024Date of Patent: December 24, 2024Assignee: Bardy Diagnostics, Inc.Inventors: Jason Felix, Jon Mikalson Bishay, Gust H. Bardy
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Patent number: 12171563Abstract: An apparatus for estimating bio-information is provided. The apparatus for estimating bio-information by using an ultrasonic signal according to an embodiment of the present disclosure includes: an ultrasonic sensor configured to acquire an ultrasonic signal from an object; and a processor configured to detect peaks from the acquired ultrasonic signal, and to determine false detection of a peak, among the detected peaks, by using at least one of amplitudes of the detected peaks or a left waveform shape and a right waveform shape of the peak.Type: GrantFiled: October 20, 2022Date of Patent: December 24, 2024Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Ui Kun Kwon, Jae Min Kang, Youn Ho Kim, Sang Kon Bae, Jin Woo Choi, Chang Mok Choi
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Patent number: 12171564Abstract: A method for detecting a QRS complex of an electrocardiogram signal, an apparatus therefor, a device and a medium are provided. A QRS complex of an electrocardiogram signal is detected by a detection model including a DenseNet and a dual-channel Long Short-Term Memory (LSTM). Spatial feature information of the QRS complex in the electrocardiogram signal is learned through the DenseNet, and then the spatial feature learned by the DenseNet and the time sequence data are input into respective channels of the dual-channel LSTM, so that the dual-channel LSTM can fuse the spatial information and the time sequence information of the QRS complex in the electrocardiogram signal, thereby improving a segmentation effect of the model on features, and finally improving accuracy of detecting the QRS complex.Type: GrantFiled: August 28, 2024Date of Patent: December 24, 2024Assignee: Central South UniversityInventors: Lin Guo, Nan Ma, Ying An, Qianyun Zhan, Jun Long
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Patent number: 12171565Abstract: The invention relates to a hybrid intracerebral electrode comprising a narrow, elongated body intended to be implanted in the brain of a patient in order to carry out at least one multi-scale electroencephalographic exploration. Said hybrid intracerebral electrode comprises, in its active part, a plurality of first electrical contact elements forming stationary macro-contacts, and a plurality of second electrical contact elements forming movable micro-contacts. The hybrid intracerebral electrode is characterised by control means which are built into the electrode in a coupling tip integral with the body. The control means are designed to move the second electrical contact elements between a passive position in which same are retracted inside the body and an active position in which same protrude outside the body, and simultaneously to adjust the controlled projection length thereof with respect to the body of the electrode.Type: GrantFiled: February 12, 2020Date of Patent: December 24, 2024Assignee: DIXI MEDICALInventors: Lucie Petegnief, Jérémy Fumey
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Patent number: 12171566Abstract: One variation of a system for locating electrodes on a head of a user includes a headset defining a set of electrode bodies elastically interconnected by a unique set of spring elements configured to locate the set of electrode bodies at electrode positions of the international 10-20 standard, irrespective of the size of the head of the user. The spring elements are configured to carry electrical signals between interconnected electrode bodies and ultimately to a controller. An electrode tip is mechanically and electrically coupled to each electrode body. The electrode tip comprises a thin conductive probe mounted at the distal end of an elastic beam and is configured to extend from a base of the electrode tip, bypass hair, and electrically couple to the head of the user, and an insulative boss, configured to rest on and transfer the weight of the headset to the head of the user.Type: GrantFiled: July 11, 2023Date of Patent: December 24, 2024Assignee: Zeto, Inc.Inventors: Peter Kele, Janos Kokavecz, Gabor Braun, Aswin Gunasekar
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Patent number: 12171567Abstract: A processing subsystem generates perceived images from information bearing nerve impulses that are transmitted from a subject's eye(s) to a visual processing region of the subject's brain along one or more nerves in response to the subject viewing a real-world scene. The processing subsystem generates display images based on the perceived images, and controls a display device to display the display images to the subject. In certain embodiments, the processing subsystem generates the display images by manipulating or modifying the perceived images to include virtual images, and provides a type of virtual pointing on the display images that is used to invoke one or more actions.Type: GrantFiled: February 28, 2023Date of Patent: December 24, 2024Inventor: Moshe Ofer
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Patent number: 12171568Abstract: The present invention is directed to a method for inducing an immune response in a subject, including a step of activating neurons in the mesolimbic network of the subject by applying a neurofeedback.Type: GrantFiled: March 3, 2020Date of Patent: December 24, 2024Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, ICHILOV TECH LTD., RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Talma Hendler, Asya Rolls, Nitzan Lubianiker, Tamar Koren, Neomi Singer, Tamar Ben Shannan, Shai Shen Orr, Fahed Hakim, Hilla Azulay-Debby, Rani Cohen
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Patent number: 12171569Abstract: Methods, systems, and devices for miscarriage identification are described. A system may be configured to receive physiological data associated with a user that is pregnant and collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values. The system may then identify that the temperature values are lower than a pregnancy baseline of temperature values for the user and detect an indication of an early pregnancy loss of the user. The system may generate a message for display on a graphical user interface on a user device that indicates the indication of the early pregnancy loss.Type: GrantFiled: March 31, 2022Date of Patent: December 24, 2024Assignee: Oura Health OyInventors: Nina Nicole Thigpen, Neta A. Gotlieb, Gerald Pho, Kirstin Elizabeth Aschbacher
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Patent number: 12171570Abstract: A multi-sensor patch for simultaneous abdominal monitoring of maternal and fetal physiological data includes a multi-layer flexible substrate with a center region and a plurality of electrode regions. A conductive layer of the flexile substrate provides an electrical connection between each of the plurality of electrode regions and the center region. A plurality of electrodes are formed into the flexible substrate. At least one mechanical motion sensor is connected to the multi-layer flexible substrate. A module unit is connected to the conductive layer at the center region. The module unit includes a controller configured to receive biopotential physiological data from the plurality of electrodes and mechanical sensor data from the at least one auxiliary sensor. The controller calculates at least fetal heart rate, maternal heart rate, and uterine activity from the biopotential physiological data and from the mechanical sensor data.Type: GrantFiled: April 16, 2020Date of Patent: December 24, 2024Assignee: GE Precisions Healthcare LLCInventors: Jean-Francois Pieri, Steven M. Falk
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Patent number: 12171571Abstract: Device and method for determining an efficacy of chronic pain treatment including providing a first set of at least one stimulus to a subject, obtaining first measurements of at least two physiological parameters in response to the first set of at least one stimulus, providing chronic pain treatment to the subject, providing a second set of at least one stimulus to the subject, obtaining second measurements of the at least two physiological parameters in response to the second set of at least one stimulus; and determining an efficacy of the chronic pain treatment by applying a classification algorithm on the first and second measurements of the at least two physiological parameters.Type: GrantFiled: August 23, 2023Date of Patent: December 24, 2024Assignee: MEDASENSE BIOMETRICS LTD.Inventors: Galit Zuckerman-Stark, Noam Racheli, Nir Ben-Israel
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Patent number: 12171572Abstract: The present disclosure provides a method, performed in an accessory device, for communicating the operating state of the ostomy appliance, which in turn enables a monitoring of the ostomy appliance at the accessory device. The accessory device comprises an interface configured to communicate with one or more devices of an ostomy system. The one or more devices comprise a monitor device, and/or an ostomy appliance configured to be placed on a skin surface of a user or on any additional seals. The method comprises obtaining monitor data from the one or more devices. The monitor data is indicative of a condition of the ostomy appliance. The method may comprise determining an operating state of the ostomy appliance based on the monitor data obtained. The operating state may be indicative of adhesive performance of the ostomy appliance. The method comprises communicating the operating state of the ostomy appliance via the interface.Type: GrantFiled: December 20, 2018Date of Patent: December 24, 2024Assignee: Coloplast A/SInventors: Jais Ask Hansen, Niels Hvid, Daniel Gewecke Daugaard-Jensen, Peter Flintholm Soerensen, Dan Boegsted Andersen
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Patent number: 12171573Abstract: A blood vessel position display device (1) includes an image processing device (31) configured to subject an image for analysis of a target part (2) to image processing to acquire blood vessel information including positions and shapes of blood vessels included in the target part (2), a selection device (32) configured to choose blood vessels as conforming blood vessels in which a parameter obtained from the blood vessel information satisfies specific conditions, an image generation device (33) configured to generate a projection image including display lines at least set to have lengths corresponding to the conforming blood vessels, and a projection device (40) configured to cause the positions of the display lines to correspond to the positions of the conforming blood vessels so as to project the projection image on the target part (2).Type: GrantFiled: February 28, 2020Date of Patent: December 24, 2024Assignee: Kabushiki Kaisha Nihon MicronicsInventors: Yuki Saito, Yoshiyuki Fukami, Hiroshi Kamiya, Osamu Arai, Kazuhiko Sasagawa, Koichi Sagawa, Yasutaka Hanada, Toshiro Ono
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Patent number: 12171574Abstract: A fastener according to the present disclosure includes a main unit, an adjuster unit which extends from the main unit and which is capable of being elastically inflected, and a cover unit coupled to the main unit through the adjuster unit. The cover unit is configured to be, by elastic flection of the adjuster unit, both in a state apart from the main unit and in a state latched with the main unit so as to cover the main unit, and with the cover unit being in the state latched with the main unit, a side surface of the main unit and a surface of the adjuster unit are apart from each other, the surface of the adjuster unit facing the side surface.Type: GrantFiled: March 1, 2021Date of Patent: December 24, 2024Assignee: ICUCO INC.Inventor: Yoichi Yanase
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Patent number: 12171575Abstract: Intraoral systems and methods including aligners having soft tissue sensors. The soft tissue sensors may detect protein biomarkers to determine effectiveness of the aligners for causing tooth movement according to a treatment plan. One or more microneedles may be configured to pass the protein biomarker to the soft tissue sensor. A processor may be configured to compare a detected level of the protein biomarker to an expected lever of the protein biomarker, and determine whether an aligner should be replaced. A bias may be configured to apply continuous force to hold the microneedle(s) against a patient's soft tissue. A controller may be configured to apply a biasing force to move the microneedles(s) from a retracted position to an extended position to penetrate the patient's soft tissue.Type: GrantFiled: October 4, 2018Date of Patent: December 24, 2024Assignee: Align Technology, Inc.Inventors: Avi Kopelman, Srinivas Kaza
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Patent number: 12171576Abstract: A conformal patch device can be provided to a patient. The patch device can include sensors configured to be positioned over a chest of a patient. The sensors can include PPG sensors, ECG sensors, and SCG sensors. The conformal patch device can adhere to a single continuous area of the chest. Some sensors may attached to a viscoelastic substrate to achieve mechanical isolation from other patch components. The conformal patch device can capture measurements from the sensor doing a time window sufficient enough to detect disordered breathing. The system can determine disordered breathing and related cardiorespiratory parameters during the time window for the patient using the sensor measurements.Type: GrantFiled: June 21, 2023Date of Patent: December 24, 2024Assignee: Huxley Medical, Inc.Inventors: Nathan Zavanelli, Brennan Torstrick, Nick Bolus, Mohsen Safaei, Brett Klosterhoff
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Patent number: 12171577Abstract: The purpose of the present invention is to provide an implement for positioning electrocardiographic measurement electrodes, with which it is possible to rapidly determine electrocardiographic electrode positions customized for individual patients. This implement (1) is for positioning electrocardiographic measurement electrodes, and has a plurality of holes (3, 5, 7, 9, 11, 13) corresponding to the positions of chest electrodes. The implement (1) preferably has a transparent front body section (19). The front body section (19) preferably has a plurality of cut-out holes (45). The implement (1) may have cut-out parts (47) that connect the plurality of holes.Type: GrantFiled: May 30, 2019Date of Patent: December 24, 2024Assignee: JAPANESE ORGANIZATION FOR MEDICAL DEVICE DEVELOPMENT, INC.Inventor: Takahiro Uchida
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Patent number: 12171578Abstract: A physical area network for detecting head injuries described herein enables significantly improved cranial health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and information. The physical area network is able to implemented as an apparatus, which includes a headgear with cushioning and nano-nodes embedded on or in the headgear. The nano-nodes are able to store and release a first substance and a second substance. The first substance and the second substance interact to provide extra cushioning.Type: GrantFiled: March 10, 2023Date of Patent: December 24, 2024Inventor: Lucas J. Myslinski
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Patent number: 12171579Abstract: A method for monitoring intoxication of a user, the method including: receiving a set of samples from a body region of a user; generating an intoxication metric based on the set of samples; and providing a notification to the user based on the intoxication metric. The method can additionally or alternatively include: modifying operation of the transdermal alcohol sensing device based on the intoxication metric; determining contextual data; maintaining a hydration level of the transdermal alcohol sensing device; and any other suitable processes. A system for monitoring intoxication of a user including a sensor and a housing. The system can additionally or alternatively include any or all of: an inlet, a fastener, an electronics subsystem, a user device, and/or any other suitable component.Type: GrantFiled: November 29, 2023Date of Patent: December 24, 2024Assignee: KHN Solutions, LLCInventors: Keith Harry Nothacker, William Tammen, Raymond Kampmeier
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Patent number: 12171580Abstract: A medical capsule including an electrical circuit and an internal power source for selectively supplying the electrical circuit with electrical energy, wherein at least a photosensitive element is provided for initiating a supply of electrical energy to the electrical circuit when a light signal having a predetermined intensity is irradiated and the invention related to a system comprising a medical capsule in a package, and an extracorporeal device including a light source for emitting a light beam, wherein the package of the medical capsule is adapted and provided to be permeable for the predetermined intensity.Type: GrantFiled: January 28, 2021Date of Patent: December 24, 2024Assignee: Ovesco Endoscopy AGInventors: Sebastian Schostek, Gunnar Anhöck, Marc O. Schurr
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Patent number: 12171581Abstract: A microcontroller coupled to sensors integrated into a physical toy for monitoring free play activity of a human subject wherein patterns in play activity sensed by the microcontroller are graphically visualized for identification of behavioral milestones, developmental progress and/or behavioral disorders. Specifically, accelerometers detect movement of toys which determine: (1) if the toy is being played with; and (2) the intensity in which the toy is moved. Pressure sensors detect the level and location in which a child may hold a toy. Synchronized with an audiovisual record of the play therapy session and a computer-generated avatar representation of the physical object, this data is integrated to find peak levels of behavior giving clinicians more efficient analytical tools.Type: GrantFiled: February 19, 2024Date of Patent: December 24, 2024Assignee: University of Central Florida Research Foundation, Inc.Inventors: Dalena Dillman Taylor, Dave Edyburn
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Patent number: 12171582Abstract: A biosignal sensor includes a light-emitting element, a photo-detective element configured to detect a biosignal from light reflected from an in-vivo target, a first polarizer configured to selectively transmit light in a first polarization direction, and a second polarizer configured to selectively transmit light in a second polarization direction. The light-emitting element includes a first light-emitting element overlapped with the first polarizer in a vertical direction, the photo-detective element includes a first photo-detective element overlapped with the second polarizer in the vertical direction, the first light-emitting element and the first photo-detective element are parallel to each other along a first direction that is perpendicular to the vertical direction, and the first polarization direction and the second polarization direction are perpendicular to each other.Type: GrantFiled: October 26, 2021Date of Patent: December 24, 2024Assignee: Samsung Electronics Co., Ltd.Inventors: Gae Hwang Lee, Youngjun Yun, Hyun Bum Kang, Yeongjun Lee, Jong Won Chung
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Patent number: 12171583Abstract: Systems and methods are provided for evaluating an alarm condition for a monitored patient in a population of one or more patients. One or more physiological parameters pertaining to the patient, or physiological variables, are used to form a time series describing the patient status. A quantile threshold is determined for a patient. A monitor is initialized and begins generating a binary raw alarm signal. The binary signal is filtered with a low pass filter, and the filtered data is subjected to a quantile operation to determine if a particular sample exceeds the determined quantile threshold. If the quantile threshold is exceeded, then a check is performed to see if the raw binary alarm signal also indicates an alarm. If both the preliminary alarm indication and the raw binary signal indicate an alarm, then an alarm is emitted; otherwise monitoring continues.Type: GrantFiled: April 12, 2022Date of Patent: December 24, 2024Assignee: Cerner Innovation, Inc.Inventor: Douglas S. McNair
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Patent number: 12171584Abstract: An apparatus and a method for estimating a body component are provided. According to an example embodiment, the apparatus for estimating a body component includes: a sensor configured to obtain, from an object of a user, a first spectrum in a first concentration period of a body component and a second spectrum in a second concentration period of the body component; and a processor configured to extract a first feature vector based on the first spectrum and the second spectrum, to extract a second feature vector based on a standard spectrum and the second spectrum, and to perform first calibration by generating an estimation model for estimating the body component, generation of the estimation model being based on a similarity between the first feature vector and the second feature vector.Type: GrantFiled: May 14, 2021Date of Patent: December 24, 2024Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Yun S Park, June Young Lee
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Patent number: 12171585Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.Type: GrantFiled: February 13, 2023Date of Patent: December 24, 2024Assignee: Washington UniversityInventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
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Patent number: 12171586Abstract: There is provided an output control device, an output control method, and a program to provide technologies for enabling users to control their internal states more easily. The output control device including: an output control unit configured to control output of output information in accordance with a change in a state point in a physiological index space corresponding to a physiological index value based on biosensors. The output control unit controls the output of the output information in accordance with distribution density of previous state points for which a current state point serves as a standard in the physiological index space.Type: GrantFiled: October 5, 2017Date of Patent: December 24, 2024Assignee: SONY CORPORATIONInventors: Yoshihiro Wakita, Naoya Sazuka
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Method of estimating a hearing loss, a hearing loss estimation system and a computer readable medium
Patent number: 12171587Abstract: A method of estimating a hearing loss based on a parameterized representation of a plurality of audiograms and a hearing estimation system adapted to carry out the method.Type: GrantFiled: January 14, 2021Date of Patent: December 24, 2024Assignee: Widex A/SInventors: Jens Brehm Bagger Nielsen, Asger Ougaard, Andreas Trier Poulsen -
Patent number: 12171588Abstract: A sterile holder for sterile surgical implants. The implant holder is an ergonomically shaped body of deformable material having an implant-receiving cavity similar in size and shape to the implant. To remove the implant from the holder, the surgeon mates a sterile tool to the implant and gently pries the implant out of the holder by deforming the body. Preferably the tool used to pry the implant out of the body is an insertion tool mated to the implant which is also used to insert the implant in a patient. In this way the surgeon retrieves the implant from its container without touching the container and directly inserts the implant in the patient without risking contamination: sterility is maintained for both the surgeon and the implant. In a preferred embodiment, the implant holder is configured to hold two pedicle screws and their set-screws.Type: GrantFiled: January 31, 2024Date of Patent: December 24, 2024Inventors: David Brumfield, B. Thomas Barker, Murali Kadaba, Dennis Crandall
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Patent number: 12171589Abstract: A medical packaging device, packaging system, method for producing a packaging device, and method for sterile packaging of a sieve basket with a packaging device. The packaging device defines a receiving space for accommodating a sieve basket in a packaging position, and an insertion opening for inserting a sieve basket into the receiving space. The insertion opening is open in an insertion position. The packaging device is made from a flat material sheet that is folded multiple times. The receiving space has two abutting receiving space flat material sheet surface regions. The regions are delimited by at least three fold lines of the flat material sheet such that the receiving space is closed on all sides except for the insertion opening. The packaging device includes an unfolding securing device for securing the packaging device in the insertion position against being completely unfolded back into the starting position.Type: GrantFiled: June 6, 2023Date of Patent: December 24, 2024Assignee: Aesculap AGInventors: Matthias Henke, Philipp Bohnenstengel
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Patent number: 12171591Abstract: An imaging system and methods including a gantry defining a bore and an imaging axis extending through the bore, and at least one support member that supports the gantry such that the imaging axis has a generally vertical orientation, where the gantry is displaceable with respect to the at least one support member in a generally vertical direction. The imaging system may be configured to obtain a vertical imaging scan (e.g., a helical x-ray CT scan), of a patient in a weight-bearing position. The gantry may be rotatable between a first position, in which the gantry is supported such that the imaging axis has a generally vertical orientation, and a second position, such that the imaging axis has a generally horizontal orientation. The gantry may be displaceable in a horizontal direction and the system may perform a horizontal scan of a patient or object positioned within the bore.Type: GrantFiled: September 25, 2023Date of Patent: December 24, 2024Assignee: Mobius Imaging, LLCInventors: Eugene A. Gregerson, Russell Stanton, Michael Connor, Michael Allen, Paul Sebring, Robert Coughlin Powell
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Patent number: 12171592Abstract: The present invention is directed to a computing system and method for the real-time automatic identification and tracking of a medical instrument and optionally the identification of at least one anatomical object in an image generated by an imaging system. The method includes generating the image via the imaging system and providing the image to a processor of a computing system. Further, the method includes developing and training at least one machine-learned model to automatically identify or locate the medical instrument and optionally at least one machine-learned model to identify or locate the anatomical object and the surrounding tissue in the image. Moreover, the method includes automatically labeling the identified medical instrument and optionally the identified anatomical object and surrounding tissue on the image. Further, the method also includes displaying the labeled image to a user in real-time.Type: GrantFiled: August 30, 2019Date of Patent: December 24, 2024Assignee: Avent, Inc.Inventors: Michael R. Avendi, Joost L. Mulders