Abstract: A respiratory system includes a first patient interface for delivery of a flow of gases to a patient, a second patient interface for delivery of a second flow of gases to the patient, and a device that switches the system between a first respiratory mode and a second respiratory mode. In the first respiratory mode, the flow of gases are delivered to an outlet of the first patient interface when the second patient interface is absent from the patient. In the second respiratory mode the device reduces or stops delivery of the first flow of gases to the outlet of the first patient interface when the second patient interface is located together with the first patient interface upon the patient.

Abstract: A tubing assembly for use with a patient interface device includes a manifold portion structured to be coupled to a conduit carrying a flow of breathing gas and a number of tubular portions. Each tubular portion extends from the manifold portion to a distal end which is structured to be coupled to the patient interface device. Each tubular portion is structured to communicate the flow of breathing gas from the manifold portion to the patient interface device. Each tubular portion comprises an adjustment element which provides for a characteristic of the tubular portion to be selectively varied.

Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.

Abstract: A respiratory assistance apparatus includes a flow generator and a humidifier. The humidifier includes a humidification chamber. The humidification chamber comprises a water tub that is configured to receive a volume of water. A lid is hingedly coupled to the water tub for enclosing a volume contained within the water tub.

Abstract: A music matching application system with use of AGEs and a method thereof, using a sensor unit of a wearable device to detect a first parameter value of a skin surface, followed by using a computation processing unit to perform computation process based on the first parameter value in order to obtain an electric signal and to convert into a corresponding concentration value of the AGEs. In addition, a music unit is driven to correspondingly play one of the first music menus according to the concentration value, and different music program can be provided according to the concentration level, and a second music menu is further played according to a concentration change amount corresponding to a time interval. Consequently, the effect of the music program can be enhanced.

Abstract: This present invention relates to a tactile sensory relaxation platform or card preferably having between two and ten different tactile objects affixed to at least one of its surfaces. The relaxation platform/card allows individuals suffering from anxiety, PTSD, panic attacks and the like to alleviate stress, anxiety, panic and other mental health conditions and avoid engaging in dangerous or undesirable activities. More specifically, the individual may touch or rub the affixed tactile objects themselves from negative thoughts and refocus their attention on the objects.

Abstract: A device for clearing obstructions from a medical tube is disclosed. The device includes an enclosure having an interior and an exterior, the enclosure comprising a distal opening for providing access to the interior of the enclosure. The device further includes a spool provided within the enclosure that is rotatable about an axis and an elongated guide member coupled to the spool such that the rotation of the spool causes the elongated guide member to wind or unwind about the spool. The device further includes a drive mechanism that is operable to rotate the spool within the enclosure without compromising a sterile field within the enclosure.

Abstract: A catheter and a method of making a device having an outer member, a primer, and an inner liner laminated to the outer member. The primer is provided between the outer member and the inner liner and annealed to secure the inner liner to the outer member.

Abstract: A urinary catheter package with a case having a hollow tube which is closed at one end and open at the other end, the hollow tube having a wall and a pierceable cover attached to the open end of the hollow tube. Also an assembly including the urinary catheter package and a catheter with a funnel at a first end.

Abstract: A catheter procedure system including a bedside system and a remote workstation is provided. The bedside system includes a catheter including an expandable percutaneous intervention device, a robotic catheter system configured to move the catheter, and an inflation device configured to cause expansion of the expandable percutaneous intervention device. The remote workstation includes a user interface configured to receive a at least first user input and a second user input and a control system operatively coupled to the user interface for remotely controlling both the robotic catheter system and the inflation device. The remote workstation includes a monitor configured to display information related to the expandable percutaneous intervention device.

Abstract: The invention relates to a wetting mechanism 20 for wetting a tube 12 of a catheter 10. The wetting mechanism 20 includes a housing 16 to be positioned at or proximal to the tip end 13 of the catheter tube 12, where the housing 16 comprises a holding chamber 22 and a wetting chamber 23. The wetting mechanism 20 comprises a fluid release control component 26 for controlling release of fluid within the holding chamber 22 into the wetting chamber 23. At least a portion of the catheter tube 12 is then able to be introduced and be moved through the wetting chamber 23 to wet the catheter tube 12, in use.

Abstract: A guiding sheath has a braided layer for improved deflection characteristics and ring electrodes for electrical sensing, mapping and visualization, wherein lead wires for the ring electrodes are passed through lumened tubing position under the braided layer in a proximal portion of the guiding sheath shaft and above the braided layer in a distal portion of the guiding sheath shaft. Moreover, the hemostatic valve includes an improved friction ring with air vents to reduce the risk of air being introduced into the valve.

Abstract: An elongate, flexible, medical device having distal and proximal ends, including an inner member having a proximal and distal end, a support member extending around the inner member between the proximal and distal end, a plurality of electrically-conductive wires, each braided with the support member having a proximal and distal end, an outer member surrounding the inner member, the support member, and the plurality of electrically-conductive wires and an actuator including a polymer electrolyte layer secured adjacent to the distal end of the elongate, flexible inner member and defining an exterior surface, electrodes distributed about the exterior of the polymer electrolyte layer. The distal end of one of the electrically-conductive wires is electrically connected to one of the electrodes. The polymer electrolyte layer is configured to deform asymmetrically in response to the application of an electrical signal through the plurality of electrically-conductive wires to the plurality of electrodes.

Abstract: A retainer includes a first arcuate wall and a second arcuate wall that together define a channel designed to receive a medical article. The retainer has an open configuration wherein a first end of the first arcuate wall is spaced away from a first end of the second arcuate wall, and a closed configuration wherein the first end of the first arcuate wall is adjacent the first end of the second arcuate wall. A second end of the first arcuate wall opposite the first end of the arcuate wall may be spaced away from the base in the open configuration and pressed against the base in the closed configuration. The retainer also may include a first support and a second support fixed to the base, and a first and second flexible coupling connecting the first and second supports to the first and second arcuate walls.

Abstract: A system and method of unloading a heart chamber is described. The chamber can be a ventricle and the system can unload the ventricle during or after a heart attack. The ventricular unloading system includes a transthoracic needle insertable into the ventricle, a vascular access cannula insertable into a blood vessel, and a pump to move blood from the ventricle to the blood vessel through the transthoracic needle and the vascular access cannula. The ventricular unloading system can be used by an emergency medical technician in a non-hospital setting. Accordingly, the ventricular unloading system can provide early protection against infarct to improve clinical outcomes for a patient. Other embodiments are also described and claimed.

Abstract: A catheter system may include a needle assembly coupled to a catheter adapter. The needle assembly may include a housing, an introducer needle, a distal opening, a first magnet, and a second magnet. In response to proximal withdrawal of the introducer needle, the first magnet may move towards the second magnet, which may block the distal opening and/or prevent blood from leaking out the distal opening.

Abstract: A functionally integratable catheter system comprising functional units that can be assembled to produce different configurations. The functional units include: one or more FICS support catheters; one or more FICS dilators: one or more FICS PTA catheters; and one or more FICS lock-grip handles. Functional units can be provided in a pre-assembled form by the manufacturer, optionally pre-packaged as a device tray, for assembly into different configurations by clinical operators. The configurational adaptability of the FICS platform enables physicians to efficiently address multiple procedural aspects of treatment processes, including lesion access, lesion penetration, guide-wire negotiation, lesion recanalization, and dilation, by providing in situ treatment options, including intraluminal and/or extraluminal recanalization, and enables multi-stage, patient-customized treatments of complex lesions in vivo, including lesion-length-selective, multi-stage angioplasty treatment.

Abstract: A drainage catheter configured for draining bodily fluid from a patient is disclosed. The drainage catheter may comprise a catheter tube with a drainage lumen and a suture lumen. A suture of the drainage catheter may be disposed within the suture lumen. The suture may be coupled to a distal end of the catheter tube and extend proximally through a hub disposed at the proximal end of the catheter tube.

Abstract: A surgical or laparoscopic method of creating and maintaining an opening in the thoracic diaphragm of a patient. The method comprising the steps of creating an incision in the thoracic diaphragm and thereby creating an opening in the thoracic diaphragm, placing a diaphragm passing part in said opening created in the thoracic diaphragm, passing from the abdomen through the thoracic diaphragm and into the thorax; wherein the step of placing said diaphragm passing part comprises placing a force transferring part of the diaphragm passing part in contact with the thoracic diaphragm, the force transferring part being adapted to transfer force between the abdominal side of the thoracic diaphragm and the thoracic side of the thoracic diaphragm while sliding against the thoracic diaphragm.

Abstract: Systems, catheters, and methods for accessing and treating along the central nervous system are disclosed including sampling systems. An example sampling system may include a filter cassette designed to filter cerebrospinal fluid. The filter cassette may have an inlet region configured to be coupled to a catheter and configured to receive cerebrospinal fluid, one or more filters, and an outlet region configured to be coupled to an outlet of the catheter and to direct filtered cerebrospinal fluid to the catheter. A sampling port may be in fluid communication with the filter cassette. The sampling port may have a first end region configured to receive cerebrospinal fluid, a stopcock, a syringe port, and a second end region. The stopcock may be configured to shift between a first position where cerebrospinal fluid is directed from the first end region to the second end region and a second position where cerebrospinal fluid is directed from the first end region to the syringe port.

Abstract: A cerebral spinal fluid shunt plug includes a shunt plug housing having a recess formed therein and a shunt valve shaped and dimensioned for positioning within the recess of the shunt plug housing.

Abstract: The disclosure provides example shunt apparatus and methods for deploying the apparatus. The apparatus includes (a) an inner catheter having first and second ends, where the inner catheter has a plurality of fenestrations extending along a portion of the inner catheter, (b) an outer catheter, where the inner catheter is positioned at least partially within a lumen of the outer catheter, (c) a deployment wire moveably arranged in a lumen of a conduit that is coupled to the outer catheter, and (d) a mesh arranged surrounding at least the first end of the inner catheter, where the mesh has a first end coupled to the inner catheter and the mesh has a second end coupled to the deployment wire, where the mesh is configured to move between a first position in an unexpanded condition having the form of a sheath to a second position in an expanded condition.

Abstract: A chemical salt composition dispensing system for dispensing controlled concentrations of aqueous chemical salt compositions to a user includes an outer housing having proximal and distal ends. The outer housing includes a base member located at the distal end of the outer housing. A sieve member is releasable to and insertable into the outer housing member. A spatially adjustable positioning member is connected to the outer housing and is flexibly secured to a shower head for positioning the outer housing and the sieve member at a selected distance between a user and the shower head. The dispensing system includes a flow control mechanism connected to the base member and is manually operated by the user to control the flow rate of the aqueous chemical composition dispensed to the user.

Abstract: The present invention relates to a dissolvable microneedle comprising needles made of a water-soluble material assembled on one side of a base, which is a sheet material having liquid-permeable cavities, wherein the needles being assembled to the base such that bottom portion of the needles is directly connected to the base, the connection of the bottom portion of the needle s to the base forming through a structure in which the bottom portion of the needles penetrates into the base (102), occupying some or all cavities of the base. The dissolvable microneedle with the structure according to the present invention is convenient to use as the penetrating structure that connects the needle s to the base can be dissolved quickly and efficiently; therefore, the base can be removed from the top skin without the needles embedded within the skin being pulled out.

Abstract: A vascular access device including a catheter adapter, a port opening, and an elastomeric valve. The catheter adapter extends along a longitudinal axis and includes a proximal end, a distal end, and a lumen extending therebetween. The port opening is formed in a surface of the catheter adapter in fluid communication with a side port of the catheter adapter and the lumen. A structural geometry of the port opening directs a fluid into the lumen in a proximal direction. The elastomeric port valve is disposed within the lumen and configured to deform in response to a transverse force applied thereto. A proximal gap may result between the inner wall forming the lumen and a proximal side of the elastomeric port valve, thereby opening a fluid path.

Abstract: The present invention relates to a guider for separating a tube, and more particularly, to a guider for easily separating a tube and a catheter which are coupled to each other. The guider for separating a tube according to an exemplary embodiment of the present invention may include: a cylindrical body portion which includes a through space which is opened at both ends thereof and formed to enable a tube to penetrate therethrough; and a wing portion which is connected to an outer surface of the body portion and transmits rotational force to the body portion.

Abstract: A disinfecting device for a Luer-activated device having a septum is disclosed. The disinfecting device includes a cap, a plunger including a standoff and a face, and a disinfectant. When the Luer-activated device is secured to the disinfecting device, the Luer-activated device is engaged with the standoff, but the Luer-activated device septum does not contact the standoff or the face.

Abstract: Described is a priming device to prime a gas from a fluid delivery system by receiving the gas and a fluid used to push the gas into a chamber, the priming device including a housing having a chamber, an inlet port, and an opening to release gas received into the chamber. The device further includes a valve extending from the inlet port toward the chamber and a cover body comprising one or more flexible protrusions extending axially inward from an inner surface of the cover body. The cover body has an open first end, an open second end, and an axis between the first end and the second end, the first end configured to couple with a male luer connector, the second end configured to couple with the inlet port of the housing, wherein the cover body is moveable relative to the housing.

Abstract: A sterile connector including: first and second connectors of the same shape including: a first (second) body portion including a first (second) joining surface; a first engaging member; and a first (second) fitting portion that fits with the first (second) tube, which is provided on a back surface of the first (second) joining surface of the first (second) body portion and which has a tip end portion for tightening the first (second) tube, an end face of the first (second) tube is configured to be positioned to project beyond the first (second) joining surface, and the sterile connector is configured such that when the first connector and the second connector are engaged such that the first joining surface faces the second joining surface, the end face of the first tube and the end face of the second tube are compressed with each other.

Abstract: A pumping system comprising a pump comprising a door for access within a housing of the pump, a pump segment configured for conveying a fluid based on compression of the pump segment, a pump segment frame for preventing said pump segment from stretching, a visual placement indicator configured for facilitating in a proper placement of the pump segment frame in the housing, and a non-pinching valve configured to be disposed in the housing and to control a flow of the fluid without requiring pinching of a tube.

Abstract: Pinch clamps are provided which generate positive displacement while also preventing rebound. To prevent rebound while providing positive displacement, the upper and lower clamping surfaces may be configured to form a pinch profile along which the tubing is compressed with the pinch point being formed at the distal end of the pinch profile. To further prevent rebound, the lower arm of the pinch clamp can include blocking ribs that interface with the upper clamping surface to prevent distal travelling of the pinch point even if the upper arm is forced into an over-engaged position.

Abstract: A medical container for accommodating a protein solution formulation, in which the medical container is formed from a cycloolefin polymer, sterilized with high-pressure steam, and suppresses oxidization of amino acid residues in a protein in a protein solution formulation accommodated in the medical container.

Abstract: A fluid injector system includes a control device operably associated with at least one drive component for use in actuating a plurality of fluid containers in fluid communication with a patient through an administration line. The control device includes at least one processor programmed or configured to enable programming of a diagnostic injection protocol comprising one or more phases according to which at least one of the first and the second fluid containers are selectively actuatable by the at least one drive component to enable injection of at least one of a first fluid and a second fluid into the patient. The control device is further programmed or configured to enable selection and commencement of at least partial preloading into the administration line of at least one of the first fluid and the second fluid in accordance with the one or more phases of the diagnostic injection protocol.

Abstract: A medical fluid-line arrangement and a medical elastomeric pump having such a fluid-line arrangement. The fluid-line arrangement transfers a medical fluid between a medical elastomeric pump and a patient port. The fluid-line arrangement has a fluid-line channel with an inlet and an outlet. The inlet connects to an outlet of the elastomeric pump, and the outlet connects to the patient port. A throttle element is connected in a fluid-conducting manner to the inlet and outlet of the fluid-line channel. A portion of the fluid-line channel extends through the throttle element. The throttle element causes a narrowing of an active-flow cross section of the fluid-line channel. The throttle element is encapsulated at least partially in a thermally conductive body having a heat-absorption surface that is larger than an outer surface of the throttle element and that is intended to be applied flat to a skin surface of a patient.

Abstract: A pump device for conveying a medical fluid, the pump device includes a membrane forming a pump volume. The membrane is expanded in a filling state of the pump volume with the medical fluid. The expanded membrane exerts a delivery pressure on the pump volume to deliver the medical fluid into a fluid-line system. The pump device also has a throttle device with a channel having an inlet connected to the pump volume and an outlet connectable to the fluid-line system. The delivery of the medical fluid through the outlet is finely adjustable to a flow rate at a time of manufacture. The throttle device has two bodies. The channel is formed between oppositely arranged surfaces of the bodies. The oppositely arranged surfaces are movable relative to each other for the fine adjustment of the flow rate during the manufacture, so that an effective length of the channel is variable.

Abstract: A needle stick prevention device (10, 110) includes a needle shield (20, 120) for selectively covering a distal end of a needle (41, 141). A needle hub (40, 140) is movably received within the needle shield (20, 120). The needle hub (40, 140) includes a proximal end (42, 142), a distal end (46, 146), a needle (41, 141) fixedly connected to the distal end of the needle hub (40, 140), and a plurality of ribs (54) or a cylinder (150) disposed between the proximal and distal ends. An actuation button movably received in a transverse opening of the needle shield (20, 120) to engage the needle shield (20, 120), the needle hub (40, 140) and a medical device. A spring (58, 158) is disposed between the needle hub (40, 140) and actuation member to automatically retract the needle (41, 141) into the needle shield (20, 120).

Abstract: A flow controller having an internal tubing is provided. The flow controller may include an upper housing having a plurality of graduations, a lower housing engaged with and slidably coupled to the lower housing, and a cavity defined between the upper and lower housings for accommodating at least a portion of internal tubing. The flow controller may further include a flexible clamp having an upper section mounted in the upper housing and a lower section slidably disposed in the lower housing. The upper and lower housings may be slidably coupled relative to each other to transition the internal tubing from (i) an open position where a lumen of the internal tubing is uncompressed by the flexible clamp to (ii) a closed position where the lumen of the tubing is at least partially constricted by the flexible clamp.

Abstract: A catheter system may include a catheter lumen, first and second electrodes, and a sensor in communication with the first and second electrodes. The sensor may be configured to detect at least one of: a bulk volume of blood within a blood vessel and extravasation of a drug from the blood vessel into soft tissue adjacent the blood vessel. Other catheter systems may include a catheter lumen and a sensing chip coupled to the catheter lumen. The sensing chip may be configured to detect at least one of: a bulk volume of blood within a blood vessel and extravasation of a drug from the blood vessel into soft tissue adjacent the blood vessel.

Abstract: A medical device comprising an infusion device comprising a fluid reservoir to contain a therapeutic fluid and a transcutaneous access tool fluidly coupled to the fluid reservoir, the transcutaneous access tool configured to deliver the therapeutic fluid subcutaneously to a patient; wherein the infusion device operates in a stand-by mode prior to the therapeutic fluid being introduced into the fluid reservoir; wherein the infusion device operates to deploy the transcutaneous access tool within a predetermined deployment time period upon filling the fluid reservoir to a predetermined fill level with the therapeutic fluid.

Abstract: An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

Abstract: An autoinjector having a reservoir (100) containing fluid and a piston; a needle; a driver (200) having a body; a piston rod (210) movable between a rest position and an injection position; an injection spring (220); and a force control mechanism (280, 290) for causing the force exerted by the injection spring to vary in predetermined manner during injection, and a lever (280) and a cam (290), the lever (280) pivotally mounted on the piston rod, being connected to the injection spring (220), and co-operating with the cam; and an interface module (300) fastened to the driver that receives a reservoir (100) before each actuation. The interface module having a selector ring (310) mounted to turn on the driver module, and pivot elements (320) fastening the reservoir module in the interface module.

Abstract: An injection device for the self-administration of an injection of solution that includes a body portion/handle configured for engagement with a cartridge containing the solution and an injection needle. The injection device includes a safety mechanism whereby ejection of solution from the injection device cannot be done unless the safety mechanism is released. The injection device further involves two-stage deployment whereby a needle may be inserted upon release of the safety mechanism and solution is injected upon full insertion of the needle.

Abstract: The present disclosure relates to a dose detection system for use in combination with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system includes a module which is removably attached to the medication delivery device. The module includes a dosing component attached to the actuator during dose delivery. The dosing component includes a light source and a light sensor. A sensed element is attached to the dose setting member and includes surface features detectable by the light sensor.

Abstract: A supplementary device is configured to be releasably attached to an auto injector type device. The supplementary device is suitable for use with disposable one-shot auto injectors and re-usable one-shot auto injectors. The supplementary device has at least one inductive proximity sensor which outputs signals indicative of the position moveable components within the auto injector. The supplementary device is configured to determine based on the outputted signals the moment at which the auto injector changes from a pre-ejection state to a post-ejection state. In response to determining that the auto injector has changed from the pre-ejection state to the post ejection state, the supplementary device displays a visual indication that a user should hold the auto injector in its current position for a predetermined period of time.

Abstract: The present disclosure relates to an injector device comprising: a housing having a distal end and a proximal end; a medicament cartridge disposed within the housing; a needle unit comprising a needle, the needle unit being disposed in the distal end of the housing; and a button disposed in the proximal end of the housing, the button being configured to move the cartridge onto the needle unit to fluidly connect the needle with the cartridge when, in use, the button is pressed from an initial position into a depressed position.

Abstract: A syringe assembly includes a syringe and a tamper evident cap disposed over a Luer connection of the syringe, the tamper evident cap having a main body that defines a proximal end defining an opening, a distal end opposite the proximal end, an outer surface, and an inner surface opposite the outer surface that defines a passage to receive a tip cap and the Luer connection, where the tamper evident cap is spaced from the tip cap. The main body defines a frangible connection between the proximal and distal ends thereof. The frangible connection can break under a force applied to the distal end of the tamper evident cap such that the proximal end of the tamper evident cap remains engaged with the syringe when the frangible connection breaks. An RFID tag is disposed on the syringe and has an integrated circuit and an antenna configured to send/receive signals between an RFID reader.

Abstract: The present invention provides an intravascular blood pump system with an external motor and comprising an impeller housing and/or impeller blade(s) that may be expandable and collapsible. The blade(s) and/or impeller housing may be biased to expand or may be expanded by centrifugal forces generated during rotation of the impeller and blades an operatively connected rotational external motor.

Abstract: A bearing assembly is configured to retain an end of an impeller of a blood pump and includes a thrust plate having a distal-facing surface and an impeller bearing surface configured to be disposed adjacent the distal-facing surface such that a gap is defined between the distal-facing surface of the thrust plate and the impeller bearing surface. The impeller bearing surface includes at least one washout blade disposed thereon and configured to facilitate blood flow through the gap.

Abstract: Described herein are methods for generating a coated device, electrode, or portion of an electrode for implanting into a subject. Such devices and electrodes are generated using methods like atomic layer deposition. In some cases, methods like etching are used to expose portions of a coated surface. The methods described herein improve overall hermeticity, biocompatibility, and biostability of implantable devices.

Abstract: A customized electrical stimulation providing system includes: an electrical stimulation request input unit receiving electrical stimulation mode selection information; an electrical stimulation control unit setting an electrical stimulation control variable according to the electrical stimulation mode selection information and generating a control signal; and an electrical stimulation providing means receiving the control signal generated by the electrical stimulation control unit and providing electrical stimulation, wherein the electrical stimulation mode selection information includes at least one of a beauty mode (muscle loss mode) and a muscle strengthening mode.