Patents Issued in March 6, 2025
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Publication number: 20250073357Abstract: Disclosed is a gadolinium-based compound, and an MRI contrast agent including same. The gadolinium-based compound may be a DO3A-based gadolinium compound to which vanillic acid is bound. The MRI contrast agent may include the compound. Also disclosed is a pharmaceutical composition for preventing or treating neuroinflammatory diseases, wherein the composition comprises the compound or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: July 21, 2022Publication date: March 6, 2025Applicant: THERANOCURE CO., LTD.Inventors: Yong Min CHANG, Bo Kyung SUNG
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Publication number: 20250073358Abstract: Provided are an aromatic vinyl compound, a metal complex thereof, and a preparation method therefor and the use thereof. The aromatic vinyl compound and the metal complex thereof have an inhibitory activity on the binding of PD-1/PD-L1, and therefore the aromatic vinyl compound and the metal complex thereof can be used for treating related diseases such as tumors. In addition, the obtained metal complex can also be used as an imaging agent.Type: ApplicationFiled: December 23, 2022Publication date: March 6, 2025Inventors: Yuguang Wang, Senlin Cai, Min He, Zhenhua Feng, Xinliang Wu, Qiang Zhao
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Publication number: 20250073359Abstract: The application is drawn to radiolabeled biomolecules and methods for radiolabeling biomolecules with radioactive halogen atoms that minimizes loss of the radioactive halogen due to dehalogenation in vivo, preserves the biological activity of the biomolecule, maximizes retention of radioactivity in cancer cells, and minimizes the retention of radioactivity in normal tissues after in vivo administration. Some such radiolabeled biomolecules comprise a radioactive metal atom in place of, or in addition to the radioactive halogen. The biomolecules have an affinity for particular types of cells and may specifically bind a certain cell, such as cancer cells. Relevant biomolecules include antibodies, monoclonal antibodies, antibody fragments, peptides, other proteins, nanoparticles and aptamers.Type: ApplicationFiled: November 13, 2024Publication date: March 6, 2025Inventors: Michael Rod Zalutsky, Ganesan Vaidyanathan
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Publication number: 20250073360Abstract: A self-disinfecting system can include a cladding having a flexible body that conforms to a substrate. The system can further include a disinfection means for disinfecting an exterior surface of the cladding. The disinfection means can be selected from a germicidal irradiation means, a photocatalytic disinfection means, or a chemical disinfection means for disinfecting the exterior surface of the cladding. The germicidal irradiation means can employ germicidal radiation from one or more locations within the body or the substrate to disinfect the cladding. The photocatalytic disinfection means can employ excitation radiation to produce reactive oxygen species using a photosensitizer incorporated into one or more polymeric layers of the body or a coating thereover to disinfect the cladding. The chemical disinfection means can employ a chemical disinfectant incorporated into the one-or-more polymeric layers of the body to disinfect the cladding.Type: ApplicationFiled: August 28, 2023Publication date: March 6, 2025Inventors: Dustin Payne, Ejaz S. Haque
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Publication number: 20250073361Abstract: The present invention relates to a radiation generating system (1) comprising a radiation unit (2), wherein the radiation unit (2) comprises a light source (3), a first collimator (4), and an optical arrangement (5). The light source (3) is configured to generate light source radiation (100) having a first spectral power distribution having an intensity I1,1 at a first wavelength ?1 and an intensity I1,2 at a second wavelength ?2. The first collimator (4) is configured in a light receiving relationship with the light source (3), wherein the first collimator (4) is configured to collimate the light source radiation (100) into collimated light source radiation (101) having an initial spatial light distribution (ISLD). The optical arrangement (5) is arranged downstream of the first collimator (4) and comprises an optical filter (6) and a diffuser (7). The optical filter (6) has a higher transmission for the first wavelength ?1 than for the second wavelength Xi when irradiated under a predefined angle 0.Type: ApplicationFiled: December 19, 2022Publication date: March 6, 2025Inventors: TIES VAN BOMMEL, ROBERT JACOB PET
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Publication number: 20250073362Abstract: A mobile system for disinfecting a surface is described, having a chamber having an inner housing at least partially surrounding the surface, a disinfectant source at the inner housing to apply a disinfectant to at least one portion of the surface, and a motor for moving the chamber along a predetermined path from a first position to a second position, the at least one portion of the surface contacted by disinfectant changing as a result of the chamber moving from the first position to the second position.Type: ApplicationFiled: November 22, 2024Publication date: March 6, 2025Inventors: Christopher J. Stankus, Robert D. Keeler
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Publication number: 20250073363Abstract: Using the existing cabin air flow/heating/air conditioning system lines or running lines in the same path the system would disperse a nontoxic sanitizer through overhead personal air flow nozzle. In existing aircraft, the air nozzles would need to be converted to run both the air and sanitizer, the sanitizer will need a wide flow misting spray. A main sanitizer canister would install in a small convenient location to connect to existing air system lines. Upon passenger and crew departure of the cabin the sanitizer would be dispersed, then air would be run to dry the lines and assist with drying the seats. Sanitizer canister can be small and refilled with each flight or a larger canister if weight isn't a concern.Type: ApplicationFiled: August 28, 2023Publication date: March 6, 2025Inventor: HEATHER MARIE STRAW
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Publication number: 20250073364Abstract: The present invention provides a breathing assistance apparatus that has a convenient and effective method of cleaning internal conduits inside the apparatus. The breathing assistance apparatus is preferably a gases supply and humidification device. The cleaning method is a method of disinfection that is automated so minimal training is required to disinfect in particular an internal elbow conduit within the device. It is therefore not necessary to dismantle the gases supply and humidification device, therefore, inadvertent damage to the internal parts of the device is avoided. The present invention also provides a method of disinfecting a heated breathing conduit and a patient interface.Type: ApplicationFiled: July 9, 2024Publication date: March 6, 2025Inventors: Kevin Peter O'Donnell, Matthew Jon Payton, Christopher Simon James Quill, Martin Paul Friedrich Kramer, Peter Geoffrey Hawkins, Reena Daken
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Publication number: 20250073365Abstract: An apparatus is provided for disinfection of an object. The apparatus includes a rotatable platform, a reflective surface on the rotatable platform, and a transmissive base to carry the object. The apparatus acquires information associated with the object, which includes one of a size of the object, a relative position, or an angular orientation of the object with respect to an ultraviolet light source. The apparatus determines one or more control parameters based on the acquired information, which includes one of a distance between the transmissive base and the reflective surface, a time period, or a speed of rotation of the rotatable platform. Based on the one or more control parameters, the apparatus controls a movement of the transmissive base and the rotation of the rotatable platform, to cause the reflective surface to reflect an ultraviolet light emitted by the ultraviolet light source onto the object, via the transmissive base.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Inventor: BRANT CANDELORE
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Publication number: 20250073366Abstract: An external sheath for a sterilization container is provided. The external sheath may have a main body comprising a net having a plurality of shaped openings along its length, a first open end and a second open end. The main body may be provided with a geometry configured for a slip fit over the wrapped sterilization container and be formed of a sterilization-grade material. The external sheath may be part of a sterilization system that also includes a sterilization container having a tray and a lid, and a sheet for wrapping the sterilization container.Type: ApplicationFiled: September 4, 2024Publication date: March 6, 2025Inventors: Jaime Zohrer, Chris Hakanson, Travis Meadow, Bruce Choi
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Publication number: 20250073367Abstract: The present disclosure relates to compositions and associated apparatuses that provide an effective microbial inhibitory headspace concentration of allyl isothiocyanate, citral, thymol, linalool, terpincol, eugenol, or a combination of any two or more thereof.Type: ApplicationFiled: September 4, 2024Publication date: March 6, 2025Applicant: S.C. Johnson & Son, Inc.Inventor: Michael S. Haas
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Publication number: 20250073368Abstract: The present utility model discloses a Bluetooth speaker table lamp with essential oil aromatherapy, including a base, an aromatherapy mechanism arranged on the base, a lamp panel arranged around the aromatherapy mechanism, a lampshade sleeved on the lamp panel and abutting against a top of the base, and an aromatherapy control board arranged at a top of the aromatherapy mechanism, where the aromatherapy mechanism includes an essential oil bottle, a microporous tube B communicating with the essential oil bottle, a silicone pad of the essential oil bottle that is arranged on a bottle mouth of the essential oil bottle, an aromatherapy chamber detachably connected to the bottle mouth of the essential oil bottle, an air pump motor arranged beside the essential oil bottle, and a microporous tube A with one end communicating with the air pump motor.Type: ApplicationFiled: December 3, 2023Publication date: March 6, 2025Applicant: Shenzhen Jiewei auspicious industrial Co., LTDInventor: Guohong XU
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Publication number: 20250073369Abstract: A photocatalyst carrier is a blower fan like impeller or a cross flow fan like impeller, or an impeller serving as a blower fan or an impeller serving as a cross flow fan. An impeller includes a pair of connecting plates that connect to each blade plate at both ends thereof in an axial direction. Each blade plate and the connecting plates are fixed in a manner that a part of each of the both ends of the blade plate penetrates and protrudes through a through groove formed in each of the connecting plates, and the protruding part is bent in a direction intersecting the axial direction and parallel to a surface of the blade plate so as to be crimped and fixed to an opening periphery of the through groove of the connecting plate.Type: ApplicationFiled: June 6, 2022Publication date: March 6, 2025Applicant: APS Japan Co., Ltd.Inventors: Teruo WATANABE, Hidemitsu WATANABE, Hiroyuki WATANABE, Takafumi WATANABE, Masao YAMAGUCHI
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Publication number: 20250073370Abstract: An aircraft lavatory is disclosed herein. The aircraft lavatory includes an air duct including an air inlet and an air outlet, the air outlet extending into an interior of the aircraft lavatory, an ion emitter coupled to the air outlet, and a control unit electronically coupled to the ion emitter, the control unit configured to control an ion output of the ion emitter.Type: ApplicationFiled: March 4, 2024Publication date: March 6, 2025Applicant: B/E Aerospace, Inc.Inventors: HEMANTH RAGHAV GAJENDRA, SAI SANKALP SHEKAR, SKANDAN BERIKAI KUPPAN
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PROCESS TO OBTAIN THREE-DIMENSIONAL BIODRESSING, THREE- DIMENSIONAL BIODRESSING OBTAINED AND ITS USE
Publication number: 20250073371Abstract: The present invention refers to a process to obtain a three-dimensional (3D) biodressing comprising the steps of (a) isolating and culturing mesenchymal cells with human AB serum; (B) performing three-dimensional (3D) bioprinting using a biomaterial such as sodium alginate and cells obtained in step “a”; (c) putting at rest the 3D biodressing obtained after bioprinting; (d) covering the 3D biodressing with a 100 mM calcium chloride solution; (e) washing the 3D biodressing; (f) adding Dulbecco's Modified Eagle Medium (DMEM); and (g) keeping the biodressing in an incubator for up to 15 days. Additionally, the present invention refers to the 3D biodressing obtained comprising, preferably 4% sodium alginate and mesenchymal cells from the umbilical cord (MCUs), which has healing, anti-inflammatory, and analgesic properties. Furthermore, the present invention relates the 3D biodressing to treat patients with chronic wounds and severe burns.Type: ApplicationFiled: June 23, 2022Publication date: March 6, 2025Inventors: Carolina Caliari OLIVEIRA, Adriana Oliveira MANFIOLLI -
Publication number: 20250073372Abstract: The present disclosure relates to a surfactant composition including an amphiphilic block copolymer based on polyhydroxyalkanoate (PHA), the surfactant composition is highly safe for the human body and the environment due to its excellent biodegradability and biocompatibility, and a hemostatic agent and medical adhesive including the same are effective in hemostasis, wound healing, tissue adhesion, and inhibition of bacterial infection.Type: ApplicationFiled: September 5, 2024Publication date: March 6, 2025Applicant: POSTECH Research and Business Development FoundationInventors: Dong Soo HWANG, Gi-Ra Yl, Geonho SONG, Yunhee JEONG
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Publication number: 20250073373Abstract: The present disclosure pertains to injectable shear-thinning compositions that comprise (a) one or more types of fibrous proteins, (b) one or more types of silicate microparticles, (c) one or more types of radiopaque additives, (d) one or more types of cryoprotectants, and (e) water. Other aspects of the present disclosure pertain to kits that contains such compositions and medical procedures that comprise administering such compositions to a patient.Type: ApplicationFiled: August 28, 2024Publication date: March 6, 2025Applicant: Boston Scientific Scimed, Inc.Inventors: Nicolas Ball-Jones, Samuel Michael Hanson, Paul Vincent Grosso, Karen Dubbin, Gary Thomas Ohrt
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Publication number: 20250073374Abstract: A method of enhancing therapeutic properties of a solid graft material with a fluid biologic may include obtaining the solid graft material and obtaining the fluid biologic to be fluidically infused with the solid graft material. The fluid biologic may include human platelets, activating the human platelets with an activation fluid to form activated human platelets, placing the solid graft material into a centrifuge container, adding the activated human platelets to the solid graft material in the centrifuge container, and placing the centrifuge container into a centrifuge and centrifuging the solid graft material and the activated human platelets to form an enhanced solid graft material.Type: ApplicationFiled: September 2, 2024Publication date: March 6, 2025Applicant: Royal BiologicsInventors: Darin EWER, Salvatore LEO
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Publication number: 20250073375Abstract: Provided herein are settable and non-settable compositions for use in surgical procedures comprising a variety of disclosed particles and optionally including previously unclotted, lyophilized, optionally crosslinked mammalian blood plasma. Also provided are related compositions, including surgical kits and packages, as well as methods of making and using the compositions.Type: ApplicationFiled: November 14, 2024Publication date: March 6, 2025Inventors: Richard L. KRONENTHAL, John PACIFICO, Aniq DARR
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Publication number: 20250073376Abstract: Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.Type: ApplicationFiled: July 9, 2024Publication date: March 6, 2025Inventors: Benjamin J. WILEY, Huayu TONG, Jiacheng ZHAO
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Publication number: 20250073377Abstract: A biocompatible surgical article is provided for cutting biological tissue or implantation in contact therewith. The surgical article has a composition of tungsten carbide—nickel with a percentage of additional metal carbides present. A typical composition in total weight percentages is WC 85 to 95%, Cr3C2, Mo2C, VC each alone or in combination being present from 0 to 2%, and Ni constituting the remainder. The composition is formed to have an mean grain size of between 200 and 800 nm with a particle dispersion index (PdI) corresponding to (the square of the standard deviation)/(mean grain size) of between 0 and 0.6, and in some embodiments between 0.02 and 0.2.Type: ApplicationFiled: November 18, 2024Publication date: March 6, 2025Applicants: THINK SURGICAL, INC., EXTRAMET PRODUCTS LLCInventors: Timothy Pack, Christopher Douglas, Joel Zuhars, Micah Forstein
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Publication number: 20250073378Abstract: According to one embodiment, a white blood cell collection apparatus includes a first container, a second container, a filter, a branching portion, and a controller. The controller controls liquid delivery operation through the branching portion. The liquid delivery operation includes: sending blood in the first container from the branching portion to the filter to cause the filter to capture white blood cells contained in the blood; pushing back the blood remaining in the branching portion toward the first container by sending the wash liquid in the second container from the branching portion toward the first container after the capturing; and washing the filter by sending the wash liquid in the second container from the branching portion to the filter after the pushing back.Type: ApplicationFiled: August 27, 2024Publication date: March 6, 2025Applicants: CANON KABUSHIKI KAISHA, Canon Medical Systems CorporationInventors: Akane KUBOYAMA, Tsutomu MIKI, Yuhi HIGUCHI
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Publication number: 20250073379Abstract: A breast pump wearable in a bra includes a main body containing battery, air pump, circuit control device and diaphragm. The breastshield includes a breast accommodating chamber, a nipple accommodating chamber and a diaphragm installation chamber. A mouth of the diaphragm installation chamber has a chamber cover having a first pipe joint communicating with an air-side vacuum chamber. The diaphragm is sealingly combined with the mouth of the diaphragm installation chamber. A milk-side vacuum chamber is formed between the diaphragm and the diaphragm installation chamber. The air-side vacuum chamber is formed between the diaphragm and the chamber cover. The diaphragm installation chamber has an air hole communicating with the milk-side vacuum chamber and the nipple accommodating chamber. The breastshield installation chamber has a second pipe joint connected with an air path of the air pump. The second pipe joint is detachably connected to the first pipe joint.Type: ApplicationFiled: May 28, 2024Publication date: March 6, 2025Inventor: JIAN CHEN
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Publication number: 20250073380Abstract: The disclosure provides a breast pump, including a milk collecting assembly and a bowl member; the milk collecting assembly comprises a hard shell and a soft rubber inner cover; the soft rubber inner cover is in contact with a breast of a user when in use; the soft rubber inner cover is disposed on one side of the hard shell towards the breast, and the hard shell is detachably connected to the bowl member. The soft rubber inner cover has deformation ability. Under negative pressure, the soft rubber inner cover can squeeze the breasts, and the collected milk can flow out of the soft rubber inner cover into the milk bowl.Type: ApplicationFiled: February 1, 2024Publication date: March 6, 2025Applicant: Shenzhen Lute Jiacheng Supply Chain Management Co., Ltd.Inventor: Jieqing Zheng
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Publication number: 20250073381Abstract: A method of producing an arteriovenous (AV) fistula includes producing an anastomosis between a primary blood vessel (e.g., a vein) and a secondary blood vessel (e.g., an artery). A collateral (or competing) blood vessel in fluid communication with one of the primary blood vessel or the secondary blood vessel is identified. A reversible flow restrictor is then applied to the collateral blood vessel to reduce a blood flow rate through the collateral blood vessel. In some embodiments, the anastomosis can be produced percutaneously. In some embodiments, the reversible flow restriction (or a portion thereof) can be removed from the collateral blood vessel. In other embodiments, the reversible flow restriction (or a portion thereof) can be adjusted to allow increased blood flow therethrough while within the collateral blood vessel.Type: ApplicationFiled: November 19, 2024Publication date: March 6, 2025Inventor: Brad M. Kellerman
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Publication number: 20250073382Abstract: A device for positioning and inserting a medical needle assembly into a patient. The device includes a base configured to be placed adjacent to a needle insertion site on the patient which includes a plurality of positioning features configured to be used for positioning and aligning the device on the patient. The device includes a needle channel and a needle guidance protrusion disposed on the top of the base. The needle guidance protrusion includes a sloped surface having a first end disposed adjacent to the needle channel and a second end displaced from the first end and is sloped such that the second end is disposed higher than the first end. A needle assembly is configured to be pushed down the sloped surface such that the needle of the needle assembly travels through the needle channel to the needle insertion site.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Inventors: McKenna M. Pruitt, Emily M. Kerivan, Kade D. Frisby, Jordan M. Kocsis
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Publication number: 20250073383Abstract: A heater-cooler apparatus of an extracorporeal perfusion system comprises at least one fluid circuit 102, 104 providing a supply of a heat transfer fluid to the perfusion system, a cold storage unit 266, and a refrigeration unit 250 for charging the cold storage unit 266. The cold storage unit 266 comprises a chamber 312 containing a liquid that freezes at a temperature above that to which the heat transfer fluid is cooled by the refrigeration unit 250, and a passage through which the heat transfer fluid is conveyed, the passage extending through the chamber 312. This allows a more effective cold storage unit to be provided.Type: ApplicationFiled: November 21, 2024Publication date: March 6, 2025Inventors: Stephen Turner, Benjamin David Garbutt
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Publication number: 20250073384Abstract: In some embodiments, a system or apparatus includes an elongated tubular member having a first end and a second end. The elongated tubular member defines a first lumen extending from the first end to the second end, and a second lumen extending from a first port, which is defined in a sidewall of the elongated tubular member, to a second port in the second end of the elongated tubular member. An inflatable member is coupled to the elongated tubular member. The inflatable member is configured to define an echogenic volume in an inflated condition. A magnetic member is disposed within the elongated tubular member. A position of the inflatable member and the first end of the elongated tubular member within a cavity of a patient can be controllable via magnetic attraction between the magnet and an external magnetic source disposed external to the patient.Type: ApplicationFiled: May 30, 2024Publication date: March 6, 2025Applicant: CoapTech, Inc.Inventors: Steven P. TROPELLO, William Alexander LeMay PATTERSON, Michael Stuart ZIMMERMAN, Jared Stephen WINEBERG, Olivia Kathryn Anne SKAUG
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Publication number: 20250073385Abstract: Infusion control systems are disclosed that can control and monitor medical fluid administration for gravity-based infusion of medical fluid, where the gravity infusion control system is couplable with an intravenous administration set and can include a mass change sensor and drop counter.Type: ApplicationFiled: August 27, 2024Publication date: March 6, 2025Inventors: Jason Andrew WINE, Ryan CALLAHAN, Siddarth SHEVGOOR
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Publication number: 20250073386Abstract: A device for delivering insulin to a user, the device configured as a wearable apparatus or system in which continuous glucose monitoring (CGM), insulin delivery and control functionality are provided to ensure insulin is delivered to the user, the device comprising: a reservoir for storing insulin; a catheter configured to deliver insulin to a subcutaneous layer of the user; an introducer needle movable with respect to the catheter, the introducer needle configured to facilitate (a) insertion of the catheter into the subcutaneous layer of the user and (b) removal of the introducer needle to enable delivery of insulin through the catheter; a micropump, in fluid communication with the reservoir and catheter, for pumping insulin from the reservoir through the catheter; and a pressure sensor separate from and in fluid communication with an outlet port of the micropump, the sensor comprising: a first wafer defining an inlet port, and outlet port and fluid channel communicating with the inlet and outlet ports; a sType: ApplicationFiled: January 16, 2023Publication date: March 6, 2025Inventors: Dilan Casanovas Mack, Jacob Menture
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Publication number: 20250073387Abstract: A medication delivery device includes an infusion pump system having a reservoir, a fluid path connected between the reservoir and an insertion mechanism, a plunger arranged inside the reservoir, and a pump drive mechanism coupled with the reservoir. The medication delivery device further includes a processing device configured to determine a user fill volume of a fluid medication by analyzing a location of the plunger inside the reservoir when a fill of the fluid medication is completed. The processing device is configured to determine the user fill volume of the fluid medication by sensing a pressure inside the reservoir.Type: ApplicationFiled: November 8, 2024Publication date: March 6, 2025Applicant: Becton, Dickinson and CompanyInventors: Scott STEWART, Abigail KRUEGLE, Muzaffer OZSECEN, J. Richard GYORY
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Publication number: 20250073388Abstract: A device for filtering liquid medication includes a housing having an injectable fluid pathway. A liquid medication filter is positioned within the injectable fluid pathway having a liquid medication pore size or a liquid medication effective pore size configured to remove particulate material.Type: ApplicationFiled: November 18, 2024Publication date: March 6, 2025Inventors: Michael D. Hooven, Matthew J. Huddleston, Joetta Renee Palmer, David Stefanchik
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Publication number: 20250073389Abstract: A controller and associated multi-axis sensor system for augmenting the automatic intelligent delivery of one or more drugs is provided. The controller and associated multi-axial sensor system are based on the detection and determination of particular physical lifestyle events. As a specific example, a pump augmentation system includes a six-axis accelerometer sensor, a gyroscopic pitch sensor and a controller. The controller is configured to receive motion data from the six-axis accelerometer sensor and orientation data from the gyroscopic pitch sensor. The controller provides a pump instruction signal for changing a delivery rate of a drug to a user based on the motion data and the orientation data. The system and methods are particularly suited for treating a user with Parkinson's disease.Type: ApplicationFiled: August 12, 2024Publication date: March 6, 2025Inventor: Arnold Chase
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Publication number: 20250073390Abstract: A drug delivery device comprising a first body part, a second body part, a first attachment part connected to the first body part and having a first distal end and a second attachment part connected to the second body part and having a second distal end. and an actuator mechanism configured to rotate one of the first body part and/or the second body part about a central axis. The drug delivery device is configured to transition from an initial configuration to an attachment configuration, and from the attachment configuration to a release configuration.Type: ApplicationFiled: January 24, 2023Publication date: March 6, 2025Inventors: Nikolaj Skak, Karsten Lindhardt, Kamille Majken Dumong Erichsen
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Publication number: 20250073391Abstract: A fixture for an automatic needle injection is disclosed, wherein the fixture comprises a housing including a chamber, the housing including a first plurality of walls, a second plurality of walls, and a third plurality of walls, a holder, and a membrane; wherein the membrane is contained in the holder, the holder is secured within a portion of the housing, and the holder is configured to allow a portion of a needle of a syringe to pass through a portion of the holder and into the chamber of the housing.Type: ApplicationFiled: August 30, 2024Publication date: March 6, 2025Applicant: Regeneron Pharmaceuticals, Inc.Inventors: Christopher HUNTER, Connor BLOCK
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Publication number: 20250073392Abstract: A medicament delivery device is presented having a housing configured to accommodate a medicament container filled with medicament, a drive unit comprising a plunger rod operable to act on the medicament container, a mechanical activation mechanism configured to interact with the drive unit, where the mechanical activation mechanism is movable between certain predetermined states when interacting with the drive unit, a recording unit capable of recording status changes of the medicament delivery device including the status of the mechanical activation mechanism, and detection elements operably connected to the recording unit and positioned such as to detect when the activation mechanism has been moved between certain predetermined states.Type: ApplicationFiled: November 18, 2024Publication date: March 6, 2025Inventor: Daniel Säll
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Publication number: 20250073393Abstract: The invention relates to a kit for refilling an implantable pump and, more particularly, to packaging and contents of a kit to improve the workflow of a user while adding medication to an implantable pump that has been surgically implanted in a patient. kit for refilling an implanted pump. The kit comprises a setup tray containing at least one needle, a fenestrated drape, a first syringe, a needle, a filter, and clampable tubing; and a medication tray containing a second syringe, at least one ampule of medication, an ampule opener, and aspiration tubing. The medication tray is molded to have a recess that securely holds the at least one ampule in both a horizontal position and in a vertical position.Type: ApplicationFiled: August 30, 2023Publication date: March 6, 2025Applicant: AMNEAL PHARMACEUTICALS, LLCInventors: Walter Lee Nash, Scott William Spencer
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Publication number: 20250073394Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Inventors: Todd ODA, George Mansour, Eugene Mason, Tomas Frausto, Dylan Beyhl
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Publication number: 20250073395Abstract: The present disclosure relates to an injection device for expelling of a number of preset or user-selectable doses of a medicament, the injection device comprising: an elongated housing extending along a longitudinal axis, and a rotatable member and a counterpart member each comprising a first mechanical code and a second mechanical code, respectively. For setting of a dose the rotatable member is rotatable relative to the housing and relative to the counterpart member. During setting of the dose the rotatable member is constrained along the longitudinal axis relative to the housing or relative to the counterpart member. For expelling of a dose one of the rotatable member and the counterpart member is displaceable along the longitudinal axis into an expelling position relative to the other one of the rotatable member and the counterpart member only when the first mechanical code is aligned with the second mechanical code.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Inventors: Andrew Gordon Wallace, Andrew Mark Lindsay, Georgina Millington, Matthew Meredith Jones, William Geoffrey Arthur Marsh, Anthony Paul Morris
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Publication number: 20250073396Abstract: A medicine dispensing device configured with an overdose indicator. The medicine dispensing device includes a substantially transparent vessel for holding a drug therein and a series of zones visible on the vessel. Each of the zones corresponds to a pre-determined dose of the drug. A first of the zones may correspond to a minimum dose of the drug for a patient population, a second of the zones may correspond to an average dose of the drug for the patient population, and a third of the zones may correspond to a maximum dose of the drug for the patient population and is marked or colored to serve as an overdose indicator. The series of zones may be printed on a label affixed to an outer surface of the vessel. Each zone may be of a different color.Type: ApplicationFiled: May 5, 2023Publication date: March 6, 2025Applicant: CD Acquisitions, LLCInventor: Caleb Hernandez
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Publication number: 20250073397Abstract: A medical device is disclosed as having a body comprising an open-ended fluid flow chamber and a laterally offset needle retraction chamber. A frontal attachment that includes a forwardly projecting needle support is slidably coupled to the body. A retractable needle assembly comprising a needle holder, a retraction spring rearwardly biasing the needle holder against the forwardly projecting needle support, and a needle extending forwardly from the forwardly projecting needle support is carried by the frontal attachment, which is laterally slidable with respect to the body from a first position in which the needle is aligned and in fluid communication with the open-ended fluid flow chamber to a second position in which the needle is aligned with the needle retraction chamber to initiate retraction of the needle holder and the needle into the needle retraction chamber.Type: ApplicationFiled: November 19, 2024Publication date: March 6, 2025Inventors: Thomas J. Shaw, Mark Small, Ni Zhu
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Publication number: 20250073398Abstract: An ultrasound blood vessel imaging system can include a 3D ultrasound probe operable to capture 3D volume data of tissue containing one or more blood vessels. A processor can be in communication with the 3D ultrasound probe and configured to receive the data and convert the data to a volume of ultrasound images. The processor can process the ultrasound images using an image segmentation method to identify a blood vessel lumen independent of surrounding tissue and generate a segmented vessel. The processor can also generate a constructed view of the blood vessel by assembling the segmented vessel and display the constructed view on an electronic display.Type: ApplicationFiled: September 5, 2024Publication date: March 6, 2025Inventors: David NARROW, Xin KANG, Andrew LANG, Damon SIMPSON, Florin NEACSU, Ralph DEL NEGRO, Serena THOMAS, Marques MANTA, Katherine CERASO
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Publication number: 20250073399Abstract: A nebulizer is provided to atomize a liquid medication for rapid delivery of an aerosol spray to a user via inhalation. The nebulizer includes a jar having a compressed gas passage. A jet cooperates with the jar and has a jet orifice through which the liquid medication and the compressed gas are discharged to form an aerosol flow. The cap is connected to the jar to define an inner chamber. The cap includes an entrainment port for ambient room air, and a chimney in fluid communication with the entrainment port and the inner chamber. A deflector base having an impingement member is located adjacent to the entrainment chimney and is spaced below an opening thereof by a predetermined distance to provide a flow of the ambient room air to be entrained in the aerosol flow in order to enhance nebulization speed while maintaining a desired aerosol particle size.Type: ApplicationFiled: November 18, 2024Publication date: March 6, 2025Inventors: Daniel P. Dwyer, Erin Hillocks
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Publication number: 20250073400Abstract: Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler.Type: ApplicationFiled: November 15, 2024Publication date: March 6, 2025Inventors: Peter John CROWLEY, Jan Geert HAZENBERG, Daniel BUCK, Josh GOTTESMAN
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Publication number: 20250073401Abstract: Disclosed is a counter structure of a dry powder aerosol delivery system, belonging to the field of inhalation devices; the counter structure includes a housing; a knob is arranged at one end of the housing; a counting disc, a transmission gear, a counting disc cover, a spring, a vibration gear and a rotating disc are arranged in the housing; the housing, the knob, the counting disc, the counting disc cover, the spring, the vibration gear and the rotating disc are arranged coaxially; the counting disc, the counting disc cover, the spring and the vibration gear are disposed around a straight rod of the rotating disc; an outer gear meshed with the transmission gear is arranged on the periphery of the straight rod.Type: ApplicationFiled: June 16, 2022Publication date: March 6, 2025Applicant: SHANGHAI XIUXIN CHENPON PHARMACEUTICAL CO., LTD.Inventors: Zhonghua TAN, Ran WANG, Yan ZHANG, Guojun LUO, Dizheng DU
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Publication number: 20250073402Abstract: An endoscopically operated plasma delivery device, in which ionization gas also suffices to provide insufflation pressure allowing the device to be maneuvered in a treated body lumen. To assist in maintaining pressure safety while avoiding interfering with the parameters of plasma generation, ionization gas evacuation is automatically adjusted in response to monitored pressure in the body lumen. In some embodiments, rapid control response is assisted by augmenting ionization gas throughput with a second gas source, and using valved switching of the proportions of gas evacuated from the two sources. In some embodiments, a faster but cruder adjustment mechanism is coupled with a slower but finer-adjusting mechanism, potentially increasing responsiveness while maintaining control of equilibrium pressures. In some embodiments, direct manual adjustment of insufflation pressure is accommodated within the operational parameters of automatically adjusting control, optionally with override.Type: ApplicationFiled: August 30, 2023Publication date: March 6, 2025Applicant: CAPS Medical Ltd.Inventors: Boris KOGAN, Ilan Oleg UCHITEL, Leonid YANOVITZ
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Publication number: 20250073403Abstract: Sleep performance scores can be generated for an individual receiving respiratory therapy. Sensor data can be obtained from one or more sensors while the user is sleeping and using a respiratory therapy system. The sensor data can be used to determine one or more usage variables associated with use of the respiratory therapy system, as well as sleep stage information indicative of the stages of sleep undergone by the user while sleeping. A sleep performance score can be calculated using the one or more usage variables and the sleep stage information. In some cases, the sleep stage information can be used to apply weightings to one, some, or all of the one or more usage variables. The sleep performance score can indicate compliance, efficacy, quality, and/or general use of the respiratory therapy system, taking into account the relationship between sleep stage and use of the respiratory therapy system.Type: ApplicationFiled: October 28, 2021Publication date: March 6, 2025Inventors: Hannah Meriel Kilroy, Redmond Shouldice, Michael John Costello
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Publication number: 20250073404Abstract: A therapeutic device with a breathing tool and a fidget spinner that can rotate, where the fidget spinner is attached to the breathing tool. The breathing tool has a proximal end with an opening that allows air to pass through an air passage and the proximal end can be enclosed in the lips of a person and allows the person to pass breathing air through the opening. The fidget spinner may encircle the air passage. The breathing tool may include: a top portion having a receiving passage; and a bottom portion with an end section adjacent to a narrow section. The fidget spinner may be adapted to rotate about the narrow section, and the end section can be received within the receiving passage of the top portion. The breathing tool, narrow section, end section, top portion, and the receiving passage of the top portion may have a cylindrical shape.Type: ApplicationFiled: August 28, 2023Publication date: March 6, 2025Applicant: The Original Anchor Pty LtdInventor: Debby Amelia Hardjadinata
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Publication number: 20250073405Abstract: A therapeutic device with a breathing tool and a fidget spinner that can rotate, where the fidget spinner is attached to the breathing tool. The breathing tool has a proximal end with an opening that allows air to pass through an air passage and the proximal end can be enclosed in the lips of a person and allows the person to pass breathing air through the opening. The fidget spinner may encircle the air passage. The breathing tool may include: a top portion having a receiving passage; and a bottom portion with an end section adjacent to a narrow section. The fidget spinner may be adapted to rotate about the narrow section, and the end section can be received within the receiving passage of the top portion. The breathing tool, narrow section, end section, top portion, and the receiving passage of the top portion may have a cylindrical shape.Type: ApplicationFiled: September 24, 2024Publication date: March 6, 2025Applicant: The Original Anchor Pty LtdInventor: Debby Amelia Hardjadinata
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Publication number: 20250073406Abstract: A central monitoring system using artificial ventilators, comprises: a plurality of artificial ventilators positioned inside a hospital room in a ward and connected to the respiratory tracts of a plurality of patients recovering inside the hospital room, so as to supply oxygen to the plurality of patients; an image-capturing unit positioned inside the hospital room so as to capture the plurality of patients in real time; a communication unit for receiving a plurality of pieces of patient condition information transmitted from the plurality of artificial ventilators and patient-capturing information transmitted from the image-capturing unit; and a communication connection unit for connecting the plurality of artificial ventilators and the communication unit, and transmitting, to the communication unit, the plurality of pieces of patient condition information transmitted from the plurality of artificial ventilators.Type: ApplicationFiled: September 16, 2022Publication date: March 6, 2025Inventors: Jae Hoon SONG, Seong Hun CHANG, Hyun Hun KIM, Gyung Tae KIM, Dong Wook SHIN