Abstract: Methods and systems for positioning a leadless pacing device (LPD) in cardiac tissue are disclosed. A delivery device is employed that comprises a proximal end, a distal end and a lumen therebetween sized to receive the LPD. The LPD has a leadlet extending therefrom that includes a means to fixate the leadlet to tissue. The delivery device comprises an introducer to introduce the LPD into the lumen of the delivery device. The LPD is loaded in the distal end of the lumen of the delivery device. The leadlet extends proximally from the LPD while the fixation means extends distally toward the LPD. A LPD mover is configured to advance the LPD out of the delivery device. A leadlet mover is configured to advance the leadlet out of the lumen delivery device and cause the leadlet to engage with cardiac tissue.

Abstract: A system for providing neurostimulation to a patient includes a pulse generator having a housing. An implantable neurostimulation lead is configured to connect with the pulse generator and the pulse generator is configured to generate a plurality of electrical impulses for delivering a neurostimulation treatment to the patient through the lead when the lead is implanted at a target location. The lead includes one or more conductors extending from a proximal end of the lead to one or more neurostimulation electrodes disposed at or near a distal end of the lead. The lead includes an energy absorber including carbon nanotube material and extending substantially along the length of the one or more conductors.

Abstract: A system and method for measuring, monitoring and mitigating EMI interference in an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a diagnostic circuit is provided for sensing an interference voltage induced at a Kelvin connect electrode of the lead system, wherein the diagnostic circuit is configured to generate one or more control signals for adjusting in substantially real time a common-mode voltage reference provided to supply a biasing voltage to the IPG circuitry.

Abstract: The present disclosure is directed to systems and methods for using interferential stimulation to reduce or prevent symptoms of motion sickness in a closed system. In an embodiment the systems and methods receive an acceleration data stream, calculate parameters of interferential stimulation likely to cause the sensation of acceleration within a person's vestibular system that matches the acceleration the person's eyes perceive. The systems and methods deliver the interferential stimulation and measure a resulting head movement. The systems and method then compare that movement to a predicted movement. If the movement is not as predicted, the systems and methods update the parameters and deliver a second interferential stimulation until a desired affect is reached.

Abstract: A pulse generation system is disclosed. The pulse generation system includes a controller, an output terminal, and a plurality of pulse generator circuits. The controller is configured to cause a driving signal pulse to be transmitted to any selected one or more of the pulse generator circuits, and to cause the driving signal pulse to not be transmitted to any selected one or more other pulse generator circuits. Each of the pulse generator circuits is configured to generate an output voltage pulse at the output terminal in response to the driving signal pulse being transmitted thereto.

Abstract: Embodiments herein relate to implantable systems for cancer treatment and related methods. In an embodiment, an implantable system for cancer treatment is included having a therapy output circuit configured to generate an electrical current for a plurality of electric field therapy electrodes to create one or more electric fields and control circuitry that causes the therapy output circuit to generate the one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz within a bodily tissue. The control circuitry can be configured to select between operating in a first mode or a second mode of generating the electrical current for the electric field therapy electrodes based on a minimum electrical field strength threshold, wherein the first mode includes modulating amplitude of the electrical current and the second mode includes duty cycling of the electrical current. Other embodiments are also included herein.

Abstract: The present invention refers to a system for stimulation of the spinal cord for the rehabilitation of motor function in subjects with spinal cord injury or other motor disorders. Said system comprises a programmable implantable pulse generator (IPG), operatively connected to deliver current pulses to one or more multi-electrode arrays, wherein said IPG is adapted to deliver to said multi-electrode array a stimulation characterized by a frequency comprised between 20 and 1200 Hz and an amplitude comprised between 0.1 motor threshold amplitude and 1.5 motor threshold amplitude. The use of such system for facilitating locomotor functions or upper limb movements in a subject with neuromotor impairments is also within the scope of the invention.

Abstract: The application relates to a device for neurostimulation with an electrically conductive stimulation wire with a diameter, a distal end and a proximal end, an electrically conductive stimulation electrode disposed at the distal end of the stimulation wire, an electrically conductive stimulation cable connected at the proximal end of the stimulation wire, an electrically insulating tubing with an inner diameter, an outer diameter, a distal end, and a proximal end, and an injection tube slipped in sections over the proximal end of the tubing forming a seal, wherein the stimulation wire is disposed within the tubing, wherein the inner diameter of the tubing is greater than the diameter of the stimulation wire such that an interspace for supplying fluid is formed in the tubing, wherein the stimulation electrode projects beyond the distal end of the tubing.

Abstract: An access control unit having a novel structure and arrangement, including a first layer comprising an electrostimulation contact interface, a second layer including a biometric sensor coupled to the electrostimulation contact interface, and a third layer including a microprocessor unit in communication with the electrostimulation contact interface. The second layer is sandwiched between the first layer and the third layer. The electrostimulation contact interface comprises one or more anode/cathode arrays configured to deliver neurostimulative excitations to the electrostimulation contact interface to elicit behavior modification.

Abstract: The present disclosure relates to an inductive coil arrangement for a transcutaneous inductive link arrangement, to devices incorporating the inductive coil arrangement and to a method of transmitting power and data using the inductive coil arrangement.

Abstract: A system may include electrodes on at least one lead configured to be operationally positioned for use in modulating a volume of neural tissue, a neural modulation generator configured to deliver energy using at least some electrodes to modulate the volume of neural tissue, a programming system configured to program the programmed modulation parameter set, including determine electrode fractionalizations for the electrodes based on a target multipole. The programmed parameter set may include the determined electrode fractionalizations. The target multipole may be used to determine electrode fractionalizations having at least three target poles that directionally and progressively stack fractionalizations of target poles to provide a linear electric field over the volume of tissue. The neural modulation generator may be configured to use the programmed modulation parameter set to provide the linear electric field over the volume of tissue.

Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.

Abstract: Methods and apparatus for improving cognitive function within a human. The invention utilizes a neurostimulation device, such as a signal generator, to affect tissue elements at a lateral temporal lobe of the human brain. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various characteristics of cognition. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation therapy.

Abstract: An example of a system may include a processor and a memory device comprising instructions, which when executed by the processor, cause the processor to: access a patient metric of a subject; use the patient metric as an input to a machine learning algorithm, the machine learning algorithm to search a plurality of neuromodulation parameter sets and to identify a candidate neuromodulation parameter set of the plurality of neuromodulation parameter sets, the candidate neuromodulation parameter set designed to produce a non-regular waveform that varies over a time domain and a space domain; and program a neuromodulator using the candidate neuromodulation parameter set to stimulate the subject.

Abstract: An exemplary embodiment of the present disclosure provides a system for generating a set of stimulation parameters, the system comprising at least one processor and a memory in communication with the at least one processor and having stored thereon instructions that, when executed by the at least one processor, is configured to cause the system to analyze, using a machine learning model, data from the deep brain stimulation device or an electromyography and generate, in response to analyzing, at least in part, the data, a set of stimulation parameters for deep brain stimulation.

Abstract: Methods of establishing and maintaining secure communication with an implantable medical device. The methods utilize enhanced identification techniques, pertaining to the person undergoing medical device implantation.

Abstract: Methods and devices for transvascular placement of electrodes in on a surface of a brain or in deep brain structures for the purpose of neuromodulation.

Abstract: A system used for neurological stimulation, includes a pulse generator module, including a first housing configured to accommodate a pulse generator unit. The first housing includes a coupling portion and a first electrical interface located at the coupling portion. The pulse generator unit is configured to generate neurological stimulation pulses to be supplied to at least one neurological stimulation electrode via the first electrical interface. A first lead interface module is connectable to the coupling portion and the first electrical interface. The first lead interface module is detachably connectable to the at least one neurological stimulation electrode. A second lead interface module is connectable to the coupling portion and the first electrical interface. The second lead interface module includes an extension cable connectable to an electrode coupling box for supplying neurological stimulation pulses generated by the pulse generator unit to the at least one neurological stimulation electrode.

Abstract: A biostimulator system includes a biostimulator having a header module and a housing module. The header module includes a fixation element, a pacing electrode, and an electrical pin. The housing module includes pacing circuitry that is electrically connected to a power source, and an electrical socket to receive and electrically connect the electrical pin to the pacing circuitry. The biostimulator system includes a biostimulator transport system to deliver the header module to an interventricular septal wall and to deliver the housing module to a ventricular chamber. The modules are then electrically connected within the ventricular chamber. Other embodiments are also described and claimed.

Abstract: Atrial appendage occlusion devices and cardiac monitoring positioned within the left atrial appendage and/or left atrium. In some embodiments the devices include an anchoring portion adapted to anchor the device in place adjacent the left atrial appendage, the anchoring portion comprising distal deformable anchoring portion adapted to be deployed in the left atrial appendage and a proximal deformable anchoring portion being adapted to be deployed in the left atrium, a barrier element secured to the anchoring portion and adapted to cover the left atrial appendage when implanted, and adapted to prevent blood clots from passing through the barrier element, and a cardiac monitoring element secured to at least one of the anchoring portions, the monitoring element including one or more sensors within in the left atrial appendage and/or left atrium and adapted to monitor left atrial cardiac data.

Abstract: Some disclosed embodiments relate to a system (and/or use of or manufacturing) that includes: a magnetoelectric (ME) component comprising: one or more first layers, wherein each of the one or more first layers comprises a piezoelectric material; one or more second layers, wherein each of the one or more second layers comprises a magnetostrictive material, and wherein a thickness ratio that is defined to be a cumulative thickness of the one or more first layers relative to a cumulative thickness of the one or more second layers is between 0.2 and 0.5. The system may also include an energy harvesting circuit comprising a rectifier circuit, where the energy harvesting circuit is coupled to the ME component.

Abstract: A user interface for a power transfer device configured to wirelessly transfer transcutaneous power to an implantable medical device. The user interface may enable a user to start and stop power transfer, e.g., to recharge a battery? on the implantable medical device. In some examples, the user interface may present the user a display that indicates whether the power transfer device is performing open or closed loop recharging, indicate and control therapy delivery? status of the implantable medical device and indicate both die power transfer device battery? level and/or indicate the battery level for the implantable medical device, lire user interface may communicate with the user with a set of indicator lights that may flash, pulse and change color as needed.

Abstract: A system and method for brain-machine interface communication utilizing Bi-Phasic Quasi-Static Brain Communication (BP-QBC). The system includes a first device and a second device that are in wireless communication together. The system and method include signal transmission between the first device and the second device through dipole coupling. The system is configured to utilize compressive sensing and collision avoidance for enhanced net energy efficiency. The system and method utilize fully electrical quasi-static signaling to militate against energy transduction losses.

Abstract: Disclosed are a timeline-based navigation feature and a channel selection feature. The timeline-based navigation feature allows the user to visually identify significant events during an episode and quickly navigate the display of data to those significant events. Embodiments of such feature allow a user to quickly see that there is a shock delivered, for example, and click on that part of a timeline navigator to advance the detailed display of data to that point in the episode. The data channel selection feature enables selection of display channel(s) from among a set of available data channels. Embodiments of such feature enable a selection and/or deselection of various channels for display to minimize display of extraneous data and/or to select preferred channels of data for review.

Abstract: A method of applying tumor treating fields to a subject's body includes: inducing a modulated electric field between a first transducer and a second transducer to treat a tumor of the subject's body, wherein the first transducer is located at a first location of the subject's body, and wherein the second transducer is located at a second location of the subject's body.

Abstract: In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

Abstract: Various embodiments provide a handheld applicator for treating skin by means of microwave radiation. The applicator comprises an applicator housing, a microwave emitter configured to emit microwave radiation for treating tissue in a target area, and an actuator assembly configured to move the microwave emitter relative to the applicator housing whilst emitting microwave radiation for increasing uniformity of tissue treatment in the target area. Other embodiments relate to an applicator pad for a handheld applicator, a skin treatment kit, a waveguide section for directing microwave radiation toward skin, and a skin treatment apparatus for treating skin by means of microwave radiation.

Abstract: A medical device has a base body on a delimiting surface of a room. The medical device furthermore has an additional body supported pivotably about a pivot axis on the base body. Thus, by pivoting the additional body about the pivot axis, it is possible to set a rotational position of the additional body relative to the base body. The additional body directly or indirectly carries a radiation source for emitting ionizing radiation. A data transmission element is on each of the base body and on the additional body in each case. The data transmission elements are arranged flush on the base body and on the additional body with respect to the pivot axis and are spaced apart from one another, seen in the direction of the pivot axis.

Abstract: Described are a light emitting diode (LED) phototherapy device control system using artificial intelligence (AI), a method of controlling the same, and a recording medium, the LED phototherapy device control system including: an LED pad to which an LED module including a plurality of LEDs arranged in a certain pattern is mounted; an LED control module; and a user equipment configured to provide a driving parameter value for the LED module to the LED control module while interworking with the LED control module, wherein the user application calculates the driving parameter value based on the data table and information input through the UI, and provides the driving parameter value to the LED control module, and the LED control module receives the driving parameter value from the user equipment, and controls the operation of the LED module based on the received driving parameter value.

Abstract: A light energy treatment method for target areas of skin or mucosa infected by herpes virus or other viral infections includes providing a plurality of light sources which generate light energy having a wavelength between 620 nm to 1500 nm; generating a series of light energy from the light sources in continuous wave mode or in pulsed mode with a pulse rate of 1 to 10000 Hz; applying the light energy in continuous wave mode or in pulsed mode to target areas of the skin or mucosa for 1 to 2000 seconds to achieve a power density between 20-500 mw/cm2; and stimulating cell mitochondria of the target areas of the skin or mucosa to increase cellular energy in the target areas of the skin or mucosa for cellular repair.

Abstract: A light-based diagnostic treatment apparatus and an operating method of a light-based diagnostic treatment apparatus are provided. The operating method of a light-based diagnostic treatment apparatus includes obtaining local images over time through a camera of the light-based diagnostic treatment apparatus, extracting an image feature point from the local images, generating a lesion map including a lesion area of a user by combining the local images based on the extracted image feature point, and generating a cumulative light irradiation map indicating accumulation information of therapeutic light output to the lesion area based on the lesion map and position information of an optical stimulation unit of the light-based diagnostic treatment apparatus.

Abstract: A brush for delivering at least one of an application of light and/or heat includes a handle and a head extending therefrom, a light emitting device and/or heating element and a plurality of hollow bristles extending from a surface of the head and receiving at least a portion of light and/or heated air or non-heated air through the bristles.

Abstract: The embodiments of the disclosure provide a phototherapy device and a phototherapy apparatus for cerebral functional related diseases. The phototherapy device comprises a headgear, irradiation assembly and a cooled gas supply mechanism. The headgear includes a housing assembly, inner side of which forms a spaced cavity with scalp of a user and is provided with a first gas inlet, the spaced cavity is constructed to form gas pathway between the first gas inlet and the scalp of the user. The irradiation assembly is mounted to the housing assembly with its light emergent side located to the inner side of the housing assembly. The cooled gas supply mechanism is interconnected to the first gas inlet through the housing assembly and supplies the cooled gas for passing through the first gas inlet and the spaced cavity sequentially and being blown toward the scalp of the user.

Abstract: The present invention is directed to enhanced methods of treating brain disorders, and devices suitable to implement these methods. In particular, the methods of treatment and related devices of the present invention utilize the coordinated application of negative suppressive stimulation of the brain hemisphere with the more negative valence in combination with transcranially applied light energy to the lateral forehead to activate the underlying cortex of the brain hemisphere with the more positive valence, e.g., synergistically. In addition, such methods and devices may be suitable to address co-morbid brain disorders (e.g., psychiatric disorder co-morbid with depression) in a more effective manner.

Abstract: Method and apparatus for directing pulsed light beams at an in vivo treatment site to create thermoelastic expansion of tissue which generates ultrasonic pulse waves in the mega hertz range. One or more photosensitizers are applied to the treatment site. Further, the ultrasonic pulse waves either singly, or in combination with the pulsed light waves cause the activation of the photosensitizers to generate singlet oxygen at the treatment site.

Abstract: A light applicator system (31), for examination and/or treatment of an organic body (5), includes a light applicator (21) having a distal-side insertion portion (1) with a light emitting element (7) at the distal end for piercing tissue (3) and a needle tip (9) at least partially distally of the light-emitting element and tapering distalwards. A positioning element (33) is fixable in a position and orientation relative to the organic body and has a receptacle (35) for the light applicator providing an orientation. The light applicator (21) has a movable protective sleeve (39) with an axial position that protectively surrounding the needle tip and an axial position based on the position of the insertion portion relative to the positioning element that is pushed back relative to the insertion portion proximalwards from the needle tip. The protective sleeve serves as an insertion sleeve into the receptacle of the positioning element.

Abstract: A photodynamic therapy and photoacoustic measurement coexistence system includes a pulsed light source configured to emit a pulsed light; a light-splitting unit, disposed on an optical path of the pulsed light, and configured to split the pulsed light into a first split light and a second split light; a reflecting unit, disposed on an optical path of the first split light, and configured to reflect the first split light into a reflected light; a first lens, disposed on an optical path of the reflected light, and configured to refract the reflected light to an irradiated surface to form a first light spot; and a second lens, disposed on an optical path of the second split light, and configured to refract the second split light to the irradiated surface to form a second light spot.

Abstract: Embodiments described herein provide for radiotherapy treatment plan generation using a machine learning language processing model. A processor can present a user interface providing an interaction interface between a user and a machine learning language processing model. The processor can receive a first input comprising a first patient attribute of a patient. The processor can execute the machine learning language processing model using the first patient attribute as an input to generate a response requesting a second patient attribute. The processor can present the response requesting the second patient attribute of the patient. The processor can receive a second input comprising the second patient attribute of the patient. The processor can transmit the first patient attribute of the patient and the second patient attribute of the patient to a radiotherapy plan optimizer. The radiotherapy plan optimizer can be configured to generate a radiotherapy treatment plan for the patient.

Abstract: Systems and methods for proton therapy treatment planning can include a treatment planning system determining positions of a plurality of energy layers across a dimension of a planning target volume (PTV) along a proton field direction, such that each pair of consecutive energy layers are spaced by a distance that is proportional to a width of a Bragg peak corresponding to at least one energy layer of the pair of energy layers. The treatment planning system can generate a proton therapy plan for irradiating the PTV according to the sequence of energy layers.

Abstract: Disclosed herein are methods and systems for predicting how internal organs change and using the prediction in image-guided radiation therapy. A method comprises receiving an attribute of a radiation therapy treatment plan for a patient and at least one medical image of the patient; executing, by the processor, an artificial intelligence model to predict deformation data for at least one internal structure of the patient using the attribute and the at least one medical image, wherein the artificial intelligence model is trained in accordance with a training dataset comprising a set of participants and their corresponding deformation data; and generating, using the artificial intelligence model, a synthetic medical image representing the at least one medical image deformed in accordance with the predicted deformation data.

Abstract: Disclosed herein are methods and systems for predicting how internal organs change and using the prediction in image-guided radiation therapy. A method comprises receiving an attribute of a radiation therapy treatment plan for a patient and at least one medical image of the patient; executing an artificial intelligence model to predict deformation data for at least one internal structure of the patient using the attribute and the at least one medical image, wherein the artificial intelligence model is trained in accordance with a training dataset comprising a set of participants and their corresponding deformation data; and outputting the predicted deformation data.

Abstract: Disclosed herein are methods and systems to evaluate cost values for different radiotherapy treatment plans using external AI models. A method comprises receiving a radiation therapy plan objective for a patient; executing a plan optimizer to generate one or more treatment attributes for a treatment plan complying with the radiation therapy plan objectives, the plan optimizer iteratively calculating the one or more attributes, where with each iteration, the plan optimizer revises the one or more attributes of the treatment plan in accordance with a cost value; executing an AI model to calculate a second cost value for the treatment plan, wherein the AI model is trained to calculate the second cost value in accordance with a likelihood of occurrence of a health-problem for the patient after being treated via the treatment plan having the one or more attributes; and outputting the treatment plan for the patient.

Abstract: A computer-implemented method of determining dose delivered by a radiotherapy system to a plurality of locations within a region of patient anatomy includes: during a first time segment of a treatment fraction, causing the radiotherapy system to be in a first machine state; during the first time segment, delivering radiation to the region of patient anatomy; generating a first surface map for the region of patient anatomy based on surface measurements acquired during the first time segment; generating a first modified digital volume of the region based on the first surface map; and for each of the plurality of locations within the region of patient anatomy, determining a first radiation dose that is delivered to the location during the first time segment, wherein the first radiation dose is based on the first machine state of the radiotherapy system and the first modified digital volume.

Abstract: A computer-implemented method of radiotherapy for a plurality of locations within a region of patient anatomy includes: determining a first radiation dose that is delivered during a first time segment of a treatment fraction to a first location included in the plurality of locations, wherein the first radiation dose is based on a first machine state of the radiotherapy system associated with the first time segment and a first surface map of the region associated with the first time segment; based on the first radiation dose, determining a dose error associated with the first location for the first time segment; based on the dose error, determining a second radiation dose to be delivered to the first location in a second time segment of the treatment fraction; based on the second radiation dose, changing a second machine state of the radiotherapy system associated with a second time segment to a third machine state of the radiotherapy system; and delivering the second total radiation dose to the first location

Abstract: There is provided a frequency control method including acquiring a current waveform in a form of a sinusoidal wave from a voltage waveform applied to a probe in a form of a square wave or the sinusoidal wave through a Bolt Clamped Langevin Transducer (BLT) driver, sampling the current waveform by using an analog-to-digital converter and selecting a first point and a second point, which respectively have a current phase ??? and a current phase ?, in the current waveform, calculating the current phase ? by using a ratio between a current value a1 measured at a first point and a current value a2 measured at a second point, and adjusting a frequency of a voltage applied to the probe such that the current phase ? matches a target voltage phase.

Abstract: Disclosed herein is a system and method for implementing a personalized ultrasound neuromodulation system and methods with neural sensing of personalized electrophysiological data, guiding ultrasound targeting and dosage using such personalized data. Specific ultrasound transducer solutions are provided for various neural targets that enable the low-intensity focused ultrasound to modulate the central nervous system and peripheral nervous systems to treat a variety of neurological and mental disorders. A portable ultrasound console device, a wearable guiding apparatus and a compact solution for effectively and safely enabling point-of-care neuromodulation, e.g., home healthcare, are provided. Further methods for ultrasound waveform customization are also described to improve effectiveness of ultrasound neuromodulation.

Abstract: Provided herein are wearable harnesses for securing and positioning an ultrasound device on a subject. The wearable harnesses can be used to position an ultrasound transducer to a human body. The wearable harnesses may include two adjustable shoulder straps, an adjustable waist strap, a pocket for holding a power pack, and a pocket for holding the transducer. For example, the pocket for holding the transducer may be positioned over the subject's spleen such that the ultrasound transducer may be positioned over the subject's spleen. Provided herein is also a treatment unit to be used to the wearable harness, that includes an ultrasound transducer; and a mechanical lens comprising a plurality of concentric rings and configured to adjust ultrasonic waves emitted by the ultrasound transducer.

Abstract: A transcranial Focused Ultrasound (tFUS) system uses a neural network to correct skull aberrations and maximizes the transmission of ultrasound waves through the skull. A method using supervised learning generates aberration correction parameters to be used by the receiver and transmitter of the tFUS system. A method utilizing these aberration correction parameters operating on the tFUS system maximizes the coherence of ultrasound waves passing through the skull. The method maximizes the amount of power transmitted through the skull, given a fixed maximum pressure (for example, determined by regulatory requirements).

Abstract: Acoustic generating systems are provided. The acoustic generating systems include a handpiece that provides for adjustment of the penetration depth. In preferred embodiments, the adjustment of the penetration depth is provided by adjustment between a fixed part of the handpiece and an adjustable part of the handpiece. In even more preferred embodiments, adjustment of the penetration depth is provided through a plurality of interchangeable adjustable parts each configured to provide for a different penetration depth when coupled to the fixed part. Preferred embodiments further include an optical system that provides imaging of the treatment surface and is capable of adjusting to the change in penetration depth to continue to provide imaging of the treatment surface. In some embodiments, the interface between the fixed part and adjustable part of the handpiece passes through a chamber that holds a liquid acoustic coupling medium.

Abstract: A tattoo stencil includes at least one flexible sheet having a realistic design of at least one body part feature thereon. The at least one flexible sheet is configured to be applied over at least one body part of a user, thereby transferring the realistic design of the at least one body part feature to the at least one body part. The realistic design can then be used as a guide and tattooed over to tattoo the at least one body part feature to the at least one body part.