Abstract: A flow generator 21 for a respiratory therapy system configured to deliver a breathable gas flow to a patient comprises a housing 27 comprising an inlet 28 and an outlet 25 and a gas flow path between the inlet 28 and outlet 25. An impeller is mounted within the housing 27 for rotation about an axis, the impeller configured to be rotationally driven by a motor to provide a gas flow along the gas flow path. Various embodiments are disclosed in which the flow generator 21 further comprises a sensor 23 mounted in the housing 27 in the gas flow path and configured to detect a property of the gas flow. The sensor 23 may be mounted in the outlet 25 so as to project into the gas flow path. Flow generator may comprise an axial inlet 28 and a tangential outlet 25. In another embodiment the sensor 23 may be mounted in the inlet 28.

Abstract: A compact respiratory therapy device suitable for use by a patient during sleep to provide respiratory pressure therapy such as at a pressure between 4-30 cmH2O includes a housing, an inlet, an outlet, a motor including a rotor, and an impeller configured to be rotated by the rotor to deliver a flow of air from the inlet toward the outlet. The impeller includes a set of impeller blades, each impeller blade comprising a leading edge and a trailing edge; and a first shroud and a second shroud, each shroud at least partly defining a flow passage through the impeller, the first shroud comprising a wall defining a periphery of an impeller inlet. The first shroud and the second shroud are configured such that the flow passage is narrower in an axial direction at an outer portion of the impeller than at an inner portion of the impeller.

Abstract: A blower includes a housing including an inlet and an outlet, a bearing-housing structure provided to the housing and adapted to rotatably support a rotor, a motor provided to the bearing-housing structure and adapted to drive the rotor, and an impeller provided to the rotor. The bearing-housing structure includes a bearing shaft having a bearing surface that rotatably supports the rotor. The bearing shaft provides only a single bearing of the non-ball bearing type for the rotor.

Abstract: Disclosed herein is a ventilator system and method, for alveolar micro-circulation enhancement using pulse cycle harmonized ventilation pressure modulation of a patient. The system includes a sensor unit, a controller unit and a supply unit. The sensor unit is configured to sense a set of physiological parameters to determine one or more cardiovascular activities of the patient. The controller unit is communicatively coupled to the sensor unit, and is configured to determine a dynamic pattern of an oxygenated air supply for the patient based on the sensed cardiovascular activity. The supply unit is communicatively coupled to the controller unit and is configured to supply the determined pressure wave to create a dynamic alteration in the air flow pattern of the ventilated air to the patient in response to the cardiovascular activity.

Abstract: Systems and methods are disclosed for categorizing and/or characterizing a user interface. The systems and methods include generating acoustic data associated with an acoustic reflection of an acoustic signal, the acoustic reflection being indicative of, at least in part, one or more features of a user interface coupled to a respiratory therapy device via a conduit. The systems and methods further include analyzing the generated acoustic data. The systems and methods further include categorizing and/or characterizing the user interface based, at least in part, on the analyzed acoustic data.

Abstract: In some embodiments, there may be provided methods, systems, and articles of manufacture for a cuff device configured to be coupled to a rigid bronchoscope. The cuff device may include a first hollow tube comprising a proximal port and a distal port, the proximal port sized with an inner diameter that slides and couples to an exterior surface of a second hollow tube portion of the rigid bronchoscope; a balloon circumscribing at least a portion of the first hollow tube, wherein the balloon is configured to have at least two modes a deflated mode and an inflated mode; and a pilot apparatus comprising a pilot balloon and pilot tubing for inflating the balloon.

Abstract: A patient interface may include a plenum chamber pressurisable to a therapeutic pressure, a seal-forming structure constructed and arranged to form a seal with a region of the patient's face surrounding an entrance to the patient's airways, a positioning and stabilising structure to provide a force to hold the seal-forming structure in a therapeutically effective position on the patient's head, and a vent structure to allow a continuous flow of gases exhaled by the patient from an interior of the plenum chamber to ambient, wherein the patient interface is configured to leave the patient's mouth uncovered during therapy, wherein the seal-forming structure comprises two lateral support regions, each located at a lateralmost side of the seal-forming structure, and a medial region positioned between the lateral support regions, the hole passing through the medial region, and wherein the lateral support regions are thicker than the medial region.

Abstract: A respiratory mask system is provided. The respiratory mask system has a patient interface that is secured to a user's head by a headgear. The patient interface comprises a seal, a frame and a gas delivery conduit. The frame is configured to secure the seal and gas delivery conduit together. The frame comprises a recessed channel and/or headgear retaining features configured to connect the headgear to the patient interface. The frame can include an inlet collar that connects to a gas delivery conduit. The inlet collar can include bias flow holes. The headgear comprises a top strap, a pair of side arms, a yoke and a rear strap. The yoke is configured to connect to the recessed channel of the frame. The top strap, side arms and yoke form an integrally formed closed loop. The top strap can include two portions adjustably connected to each other.

Abstract: An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

Abstract: A vehicle including a plurality of interior panels that include an outer decorative layer formed of a material that includes a thermochromic coloring agent. A physiologic condition monitoring device monitors various physiologic conditions of a driver of the vehicle, and based on the physiologic conditions of the driver, a temperature of the thermochromic coloring agent can be changed to change a first color of the thermochromic coloring agent to a second and different color to influence the physiologic condition of the driver.

Abstract: A method for administering vestibular stimulation to a subject after anesthesia administration includes after reducing or ceasing administration of anesthesia, administering galvanic vestibular stimulation (GVS) to the subject; and reducing or ceasing administration of GVS at a time when an anesthetized state of the subject is reduced.

Abstract: The negative ion generator includes an air spray unit, a water reservoir unit, an oscillation illumination assembly, an outer cylinder, and an air blower unit. A dual-nozzle assembly on the air spray unit is designed with a rotary knob mechanism, providing both a vertical and an oblique channel so that users can choose between a direct or oblique spray of the mist. A high-magnetic energy ring within the air spray unit can highly magnetize the passing water molecules and reorganize them to achieve an enhancement effect. A soft water cup of the water reservoir unit employs a hook-on design, allowing users to easily replace the soft water cup and choose different essence flavors. A highly durable material is used for an outer cylinder of the negative ion generator, allowing for customizable printing of distinct patterns. This also reduces the substantial costs required for repairing or replacing ceramic casings.

Abstract: A urine backflow prevention device designed for use with catheters to prevent expelled urine from reentering the body is disclosed. The device comprises a catheter tube with an integrated housing containing a valve and a spring mechanism. The valve is made of medical-grade plastic or rubber and is configured to open in response to urine pressure (i.e., pressure sensitive) and close when urine flow ceases. The spring is made of corrosion-resistant metal and provides the necessary resistance to keep the valve closed in the absence of urine flow. This mechanism effectively prevents backflow, thereby reducing the risk of urinary tract infections. The device is positioned near the proximal end of the catheter tube and is suitable for use in various medical applications where maintaining a sterile environment is critical.

Abstract: Medical device packaging, medical device packaging assemblies, and methods for preparing and packaging medical devices. An example medical device packaging assembly may include an external package, a carrier tube disposed within the external package, the carrier tube including one or more clips configured to hold the carrier tube in a predetermined configuration, a medical device disposed within the carrier tube, and a moisture or oxygen scavenging packet releasably coupled to one of the one or more clips. The moisture or oxygen scavenging packet may comprise an outer barrier pouch, an inner container disposed within the outer barrier pouch, and a desiccant and/or an oxygen scavenging material disposed within the inner container.

Abstract: A two-stage suction catheter for rapidly clearing liquids and solids from the upper airway has a first catheter stage configured to regulate effective moderate level negative pressure level at the distal end inlet and a high-capacity catheter stage having a large aperture size that is configured to regulate effective high level negative pressure level at the high-capacity catheter distal connection inlet when the first catheter stage is separated from the high-capacity catheter stage. The two-stage suction catheter has an attachment arrangement comprising a detent that releasably the first catheter stage to the high-capacity catheter stage, wherein the detent is configured to permit separation of the stages by a one-handed separation action. Methods and systems are also described. A suction cannister lid has a high capacity port and auxiliary port that may be separately sealed by a removable cap or insertion of high-capacity tubing, respectively.

Abstract: A medical multi-lumen tube includes a plurality of inner layer tubes and an outer layer tube covering the plurality of inner layer tubes. The outer layer tube has a first region and a second region placed in the axial direction of the outer layer tube and formed of resins having properties different from each other, and the resin of one of the regions enters the other region, so as to form a wave pattern in a joint part between the first region and the second region.

Abstract: A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.

Abstract: A closed system catheter (CSC) assembly has a catheter hub assembly and a needle insertion assembly that includes a needle, a needle housing and a clip guard housed in a distal compartment of the needle housing. The clip guard has a chamber having fixedly enclosed therein a safety clip. The safety clip has two elongated arms with distal grippers and barriers that naturally bias toward each other. When the barriers are biased outwardly away from each other by the needle passing between them, the distal grippers are effected to fixedly hold the proximal end of the catheter hub of the catheter hub assembly. When not biased by the needle, the barriers return to their naturally inward biased state to cause the distal grippers to release their hold of the catheter hub, such that the clip guard and the catheter hub may be separated from each other. The barriers form a distal stop to prevent the needle from re-emerging from the safety clip.

Abstract: A system for catheter-based aspiration includes an aspiration catheter having a distal portion configured for insertion within a blood vessel of a subject, the aspiration catheter including an aspiration lumen having a distal opening at the distal portion of the aspiration catheter, an injection lumen having a distal end at the distal portion of the aspiration catheter, and an orifice located at or near the distal end of the injection lumen, the orifice configured to direct liquid into the aspiration lumen at or near the distal opening of the aspiration lumen; an injector configured to pressurize the liquid within the injection lumen, such that liquid exits the orifice and enters the aspiration lumen; and a mechanical oscillator coupled to the injector and configured to cause a pulsatile pressure of the liquid as it is injected through the injection lumen.

Abstract: Methods and use for a catheter device configured to deliver a plurality of therapeutic fluids simultaneously, in which the catheter device includes a hub, a guidewire tube extending from the hub, a plurality of fluid delivery elements extending from the hub and disposed about the guidewire tube, and a compression sheath disposable over and slidably movable relative to the plurality of fluid delivery elements. The elements are naturally biased when the compression sheath does not cover the hinge portion of each of the plurality of fluid delivery elements, and are in compressed when the compression sheath covers the hinge portion of each of the elements.

Abstract: A catheter securement device (100) for use with a catheter assembly (10) includes abase (110) configured to be removably secured to a skin (20) of a user (22), a plurality of lock tabs (140) fixedly attached to the base (110) and extending from a first major surface (112) of the base (110), and a housing (160) configured to be placed on the first major surface (112) of the base (110). The housing (160) and the first major surface (112) of the base (110) at least partially enclose the catheter assembly (10) there-between. The housing (160) includes a plurality of lock handles (162). Each lock handle (162) from the plurality of lock handles (162) defines an aperture (164) therethrough. Each lock tab (140) is configured to be received through the aperture (164) of a corresponding lock handle (162) from the plurality of lock handles (164).

Abstract: A guiding sheath, which is capable of causing a dilator and a sheath to integrally reach a carotid artery which is accessed from a radial artery and communicates with a target treatment site, and easily indwelling the sheath in the carotid artery that communicates with the target treatment site. The guiding sheath includes: a dilator in which an inner cavity, through which a guide wire is insertable is provided, over an entire length of the dilator and which includes a dilator distal end portion and a dilator main body portion; and a sheath which covers outside of the dilator and includes a sheath distal end portion and a sheath main body portion. The sheath distal end portion is disposed on a distal end side of the sheath main body portion and is formed of a material more flexible than a material forming the sheath main body portion.

Abstract: Polymeric tubing, for use with catheters or other medical devices, where the polymeric tubing includes one or more functional lumens within a wall of the tubing.

Abstract: A medical instrument may include an expandable balloon on a distal end and a handle with a knob thereon. The knob may be movable along the handle, and the handle may include a switch disposed between the handle and the knob so that the movement of the knob relative to the handle activates and deactivates a circuit connected to the switch to provide an indication of the position of the knob in relation to the handle to a console. A catheter may include an elongated catheter shaft, an expandable member distal of the elongated catheter shaft, and a handle with a knob disposed thereon. The catheter may include a switch disposed between the knob and handle so that movement of the knob activates and deactivates a circuit connected to the switch.

Abstract: A balloon catheter is described, having a reinforced, co-axial, dual lumen design. At least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element.

Abstract: Flexible high-pressure angioplasty balloons are disclosed herein which utilize an inflatable balloon positioned upon the catheter and a supporting structure secured over or along the catheter at a first location proximal to the balloon and at a second location distal to the balloon. Inflation of the balloon reconfigures the supporting structure to urge the first location and the second location towards one another thereby inhibiting longitudinal elongation of the balloon relative to the catheter. The supporting structure may surround, support, or otherwise extend over the entire length of the balloon and allows for the balloon to retain increased flexibility which enables the balloon to bend or curve even at relatively high inflation pressures.

Abstract: A pressure control valve includes a valve body with a hollow column structure, a valve cover, a valve core, a sealing device and a driving device. A side wall of the valve body is connected with a lower surface of the valve cover, and is provided with a through hole. The valve core, the sealing device and the driving device are arranged at a connection between the valve cover and the valve body. A threaded groove is provided at each end of the through hole on the side wall of the valve body. An upper surface of the valve cover is provided with a threaded hole for a bolt to pass through to be connected to the threaded groove, and a space for mounting the driving device. A cover plate is provided above the space with two sides respectively connected to the valve cover through a cylindrical pin.

Abstract: An implantable medical device for delivering therapeutic fluid to, and withdrawing cerebrospinal fluid (CSF) from, a CSF-containing space, includes a first inlet configured to be accessed by a needle of an aspiration device; a first outlet; a first fluid pathway extending from the first inlet to the first outlet; a second inlet; a second outlet; and a second fluid pathway extending from the second inlet to the second outlet. The first fluid pathway is free of a filter configured to prevent passage of a microbe.

Abstract: A cranial shunt implantable into a patient, the cranial shunt may comprise a first catheter, a second catheter and a valve assembly operatively coupled with the first and second catheters, the valve assembly comprising an inlet and a microcontroller, wherein the first catheter transfers cerebrospinal fluid (CSF) to the inlet. The cranial shunt may also comprise a pressure sensor configured to provide intracranial pressure (ICP) of the patient to the microcontroller, and a tilt sensor configured to provide an angle of orientation relative to gravity of a cranium of the patient to the microcontroller, where the valve assembly passes or blocks the CSF flow to the second catheter based on instructions from the microcontroller.

Abstract: Systems, catheters, and methods for accessing and treating along the central nervous system are disclosed including sampling systems. An example sampling system may include a filter cassette designed to filter cerebrospinal fluid. The filter cassette may have an inlet region configured to be coupled to a catheter and configured to receive cerebrospinal fluid, one or more filters, and an outlet region configured to be coupled to an outlet of the catheter and to direct filtered cerebrospinal fluid to the catheter. A sampling port may be in fluid communication with the filter cassette. The sampling port may have a first end region configured to receive cerebrospinal fluid, a stopcock, a syringe port, and a second end region. The stopcock may be configured to shift between a first position where cerebrospinal fluid is directed from the first end region to the second end region and a second position where cerebrospinal fluid is directed from the first end region to the syringe port.

Abstract: Disclosed is a catheter system (100). The catheter system (100) includes a stent (104) and a catheter (102). The catheter (102) includes a shaft (108) having a proximal end (114) and a distal end (116) such that the shaft (108) includes a first lumen (118) that extend from the proximal end (114) to the distal end (116) such that fluid is adapted to pass through the first lumen (118). The catheter (102) further includes a clamp (110) coupled to the distal end (116) of the shaft (108) such that upon passage of the fluid through the first lumen (118), the clamp (110) exhibits a closed position to hold the stent (104) and upon removal of the fluid from the first lumen (118), the clamp (110) exhibits an open position to release the stent (104).

Abstract: A tattooing device comprises a needle body, wherein the needle body comprises a needle handle, a needle mouth and a needle rod; the needle mouth is installed at one end of the needle handle; the needle rod is arranged in the needle handle; the front end of the needle mouth is provided with a needle tip opening; the outer side of the needle tip opening is provided with at least one slit; the edge of one end of the needle handle provided with the needle mouth extends towards the needle mouth and forms a flow blocking part; the interior of the flow blocking part forms an ink receiving groove around the outside of the needle mouth; and the groove bottom of the ink receiving groove is provided with at least one ink return port communicated with the interior of the needle handle.

Abstract: Devices and methods for treating a skin of a patient using a serum comprising a plurality of microbubbles and a plurality of active elements are disclosed herein. The system can comprise a handpiece comprising a proximal end and a distal end; a distal tip at the distal end of the handpiece, the distal tip configured to deliver the serum; an ultrasonic transducer in the distal tip; and an inflow port in the distal tip in fluid communication with a source configured to hold the serum, where the inflow port is configured for topical application to the skin; wherein application of acoustic energy from the ultrasonic transducer causes the plurality of microbubbles in the serum delivered to the skin to oscillate causing cavitation of the plurality of microbubbles causing permeabilization of the skin allowing for penetration of the plurality of active elements in the serum to penetrate the skin.

Abstract: A transport element for transporting a substance in a reservoir includes a transport means, such as a conduit, tube, hose or the like, and a connector arranged at an inlet end of the transport means for connecting to the reservoir such that in a connected condition in which the connector is connected to said reservoir a medium through flow connection is provided between said reservoir and the inlet end of the transport means for receiving said substance from said reservoir. The connector includes aligning and holding means for aligning and holding the reservoir in a predetermined orientation with respect to and/or position along a longitudinal axis of the connector. An infusion set, system or combination including transport element, and a method of at least fluidly connecting such a transport element to a reservoir.

Abstract: The present disclosure generally relates to port connector assemblies for delivering infusion gases during ophthalmic surgeries and procedures. In some embodiments, the connector assembly includes a connector for a surgical console and a corresponding receiver for connecting the connector to the surgical console.

Abstract: A device for connection to a medical connector, the device includes a cap body, a coupling cylinder adapted to engage with a male luer connector and a female luer connector, a bulb compartment filled with air, a reagent compartment filled with disinfectant or an antimicrobial reagent, and a passageway connecting the bulb compartment to the reagent compartment. The reagent compartment includes an exterior wall surface, an interior wall surface, an array of resealable pores densely integrated throughout the exterior wall surface and the interior wall surface of the reagent compartment, and a distal tip. The passageway may be positioned in an aperture of the proximal wall of the cap body. The coupling cylinder may include an O-ring.

Abstract: Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, an intravascular propeller is installed into the descending aorta and anchored within via an expandable anchoring mechanism. The propeller and anchoring mechanism may be foldable so as to be percutaneously deliverable to the aorta. The propeller may have foldable blades. The blades may be magnetic and may be driven by a concentric electromagnetic stator circumferentially outside the magnetic blades. The stator may be intravascular or may be configured to be installed around the outer circumference of the blood vessel. The support may create a pressure rise between about 20-50 mmHg, and maintain a flow rate of about 5 L/min. The support may have one or more pairs of contra-rotating propellers to modulate the tangential velocity of the blood flow. The support may have static pre-swirlers and or de-swirlers.

Abstract: Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, an intravascular propeller is installed into the descending aorta and anchored within via an expandable anchoring mechanism. The propeller and anchoring mechanism may be foldable so as to be percutaneously deliverable to the aorta. The propeller may have foldable blades. The blades may be magnetic and may be driven by a concentric electromagnetic stator circumferentially outside the magnetic blades. The stator may be intravascular or may be configured to be installed around the outer circumference of the blood vessel. The support may create a pressure rise between about 20-50 mmHg, and maintain a flow rate of about 5 L/min. The support may have one or more pairs of contra-rotating propellers to modulate the tangential velocity of the blood flow. The support may have static pre-swirlers and or de-swirlers.

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft and are configured to radially stabilize the axial shaft while the axial shaft rotates. Proximal and distal sleeves, which are less flexible than the axial shaft, are disposed around the axial shaft, such that the proximal and distal sleeves contact the proximal and distal radial bearings, respectively, as the axial shaft rotates. A ratio between a length of the axial shaft and a combined length of the proximal sleeve and distal sleeve is between 2:1 and 6:1. Other applications are also described.

Abstract: Apparatus and methods are described including a solid axial shaft having a shaft diameter that is less than 0.8 mm, an impeller configured for insertion into a left ventricle of a heart of a subject and coupled to the axial shaft, and a hollow drive cable coupled, at a distal end of the drive cable, to the axial shaft, and configured to rotate so as to rotate the axial shaft, thereby causing the impeller to pump blood of the subject from the left ventricle. Other applications are also described.

Abstract: Apparatus and methods are described including a blood pump that includes an impeller, and a frame disposed around the impeller. An axial shaft extends from a proximal end of the frame to a distal end of the frame. The impeller is coupled to the axial shaft. A radial bearing is configured to radially stabilize the axial shaft and aa bearing housing houses the radial bearing. A layer of elastomeric material is disposed between the radial bearing and the bearing housing. Other applications are also described.

Abstract: Apparatus and methods are described including an impeller that includes an impeller frame that comprises proximal and distal end portions and a plurality of blades. Each of the impeller blades includes a curved elongate element and at least one radial element extending radially from the curved elongate element toward a longitudinal axis of the impeller frame. Other applications are also described.

Abstract: Devices and methods for assisting blood flow are provided. The device includes a housing with an inlet and an outlet, and a fluid barrier separating the housing into a first section containing the inlet and outlet, and a second section. The device also includes an impeller shaft coupled to an impeller and a first magnet in the first section of the housing, and a drive shaft coupled to a second magnet in the second section of the housing. The first and second magnets are arranged such that rotation of the drive shaft rotates the second magnet causing rotation of the first magnet, which drives the impeller.

Abstract: The present disclosure provides a neuromodulation device that comprises at least one amplifier circuit that suppresses a common mode (CM) voltage signal in the input voltage signal. The amplifier circuit comprises an input stage to receive the input voltage signal, and a differential transconductor to provide an output current signal based on a DM voltage signal in the input voltage signal. The transconductor is provides a first CM voltage signal tapped after a non-inverting input, and a second CM voltage signal tapped after am inverting input, to CM amplifier of the amplifier circuit. The CM amplifier combines the first CM voltage signal with the second CM voltage signal, amplifies the combined CM voltage signal with an inverting gain, and provides the inverted CM voltage signal back to the non-inverting input and the inverting input of the transconductor for enabling the CM suppression.

Abstract: An in vitro training method for training genioglossus muscle strength includes adhering an electrode patch of an in vitro training device to a bottom of a chin of a user during a non-sleep period. The electrode patch receives an electrical stimulation signal from an electrical stimulation module of the in vitro training device to stimulate the genioglossus muscle of the user through transdermal electrical stimulation. The electrode patch includes a body surface adhering face and an assembling face opposite to the body surface adhering face. The body surface adhering face is adhered to the bottom of the chin of the user to align with the genioglossus muscle. The electrical stimulation module is disposed on the assembling face and in electrical connection with the electrode patch. The electrical stimulation module sends an electrical stimulation signal to stimulate the genioglossus muscle through transdermal electrical stimulation.

Abstract: A medical system is provided. The medical system includes an electrode with a backing pad having top and bottom surfaces. A conductive layer is attached to the top surface of the backing pad, and a conductive gel layer covers at least part of the top surface of the conductive layer. A first bonding layer covers at least part of the top surface of the conductive layer. The electrode can include a leadwire with a stripped end length, and at least a portion of the stripped end length is disposed between the first bonding layer and a second bonding layer that also contacts the first bonding layer. The coupled-together first and second bonding layers are disposed at least in part between the conductive layer and the conductive gel layer.

Abstract: A system for combined electromyography (EMG) measurements and stimulation of a target anatomy includes a garment with electrodes. An analog cable connects with the electrodes of the garment. A stimulator inputs electrical energy to the analog cable to deliver transcutaneous electrical stimulation. Stimulator isolation circuitry switches between connecting the stimulator with the analog cable and electrically disconnecting the stimulator from the analog cable. EMG circuitry receives analog EMG signals from the analog cable and forms digitized EMG data. EMG isolation circuitry switches between electrically connecting the EMG circuitry with the analog cable and electrically disconnecting the EMG circuitry from the analog cable. Control circuitry cyclically switches between stimulation and EMG time intervals.

Abstract: The application relates to a set for neurostimulation with a device for neurostimulation with a distal end, wherein the device comprises an electrically conductive stimulation element and a duct for the supply of a fluid, and with an indwelling cannula with an indwelling cannula conduit with a distal end and a proximal end, wherein the device comprises a first connector part and the indwelling cannula comprises a second connector part complementary to the first connector part, wherein, by connecting the first connector part and the second connector part, the device is fixable in an axial position in which the distal end of the device projects beyond the distal end of the indwelling cannula, wherein, in the connected state of the first connector part and the second connector part, the first connector part and the second connector part are connected with one another such the a circumferential first seal is formed.

Abstract: A system includes at least one data input interface configured to receive data from a plurality of transducers during implantation of a device on or in a recipient and at least one controller in operative communication with the at least one data input interface. The at least one controller is configured to access a probabilistic model of a parameterized description of a pose of the device relative to the body portion and to generate an estimate of a current pose of the device in response at least in part to the data and the probabilistic model. The system further includes at least one output interface in operative communication with the at least one controller. The at least one output interface is configured to provide information regarding the estimated pose of the device.

Abstract: A cuff for providing vagus nerve stimulation to a subject having an esophagus is disclosed. The cuff includes a helical body that is configured to wrap around at least a portion of the esophagus of the subject, the helical body having an inner surface, the inner surface having a length and a width. The inner surface defines an interior space that is configured to receive the esophagus. A first electrode is coupled to the helical body. At least one additional electrode is coupled to the helical body. The at least one additional electrode is configured to provide a polarity opposite of the first electrode.