Abstract: An atomizing nebulizer for dispensing a substance or medicament is described. The nebulizer is formed with a reservoir base releasably secured to an effluent vent cap that together capture a diffuser and integral dispersing baffle that are further formed with an uptake lumen or channel terminating with a nozzle jet. The diffuser dispersing baffle is positioned relative to the jet nozzle to optimize atomization of any of a number of such substances so as to maximize disbursement of the substance. The reservoir base also incorporates a pressurized fluid-accelerating inlet tube terminated with a metering orifice that cooperates with the nozzle jet when the inlet tube is received within the diffuser uptake lumen or channel.

Abstract: When using a drug container having an identification tag fixed or detachably provided at a predetermined position of the container, the tag having drug data on a kind and a concentration of a drug and both or one of upper and lower limits of a flow rate on a continuous infusion and the upper and lower limits, time and flow rate on a one-shot administration recorded thereon, it is possible to ensure safety by prompting for a stop of injection by a warning when a setting beyond the upper and lower limits is performed and rewrite a liquid infusing time and a flow rate and so on required to be set according to symptoms of a patient.

Abstract: A medicament delivery system comprises a nebulizer device, an open-faced mist chamber-defining element having a tubular input/output port, a tubular inhalation port connecting to the output port of the mist chamber-defining element, and a sealed unit dose ampoule adapted to fit within the mist chamber-defining element. The nebulizer device includes an ultrasonic transducer responsive to applied electrical energy to generate ultrasonic energy, an ultrasonic transmission horn between an input energy surface at an input end and an energy delivery surface at an output end. The sealed unit dose ampoule can be placed directly into the nebulizer device and acts as both the dose cup and baffle, so that the chance of spillage of drug and the number of components to be cleaned are minimized.

Abstract: A metered dose spray device administers medicine contained therein to the buccal cavity within a user's mouth upon actuation of the device. A metered dose spray device comprising an insulin solution is also provided.

Abstract: A nozzle assembly for use in atomizing and generating sprays from a fluid. The nozzle assembly includes two members, each with generally planar surfaces, that are joined together. A first set of channels is formed in the generally planar surface of a first one of the members to form, in cooperation with the generally planar surface of the second of the members, a plurality of filter passageways. A plenum chamber is formed in the first member. The plenum chamber is in fluid communication with and downstream of the plurality of filter passageways. A second set of channels is formed in the generally planar surface of the first member to form, in cooperation with the generally planar surface of the second member, a plurality of nozzle outlet passageways. These nozzle outlet passageways are in fluid communication with the plenum chamber.

Abstract: An inhaler device having a pump unit (P) for producing a stream of compressed air, a drive (G) for the pump unit and a nebuliser unit (Z) which communicates with the pump unit and which is driven pneumatically. The inhaler device produces and releases an air stream which is charged in controlled manner with fine liquid active ingredient particles. The pump unit (P) is equipped with a short-stroke piston pump. The drive takes the form of a crank gear (G) having a gear transmission which can be driven by means of a hand crank (K), the output shaft of which is kinematically connected to the pump piston via an eccentric and drives the pump piston. The inhaler device need not use any elaborate energy supply and can be built in compact and handy fashion. It can be ready for use anytime and anywhere and is therefore particularly suitable for mobile use.

Abstract: Methods for changing the body temperature of a patient by having them breathe a mist created by nebulizer. The temperature of the mist is adjusted using a heat exchanger. The methods may be used to either cool or warm patients for a variety of clinical reasons. In addition, the invention includes a device (Thermomist) that can be used for generating a mist that can be administered to patients.

Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.

Abstract: A continuous high-frequency oscillation breathing device delivers therapy during both inhalation and exhalation in order to assist in clearings secretions the lungs. A fixed shrouded-venturi patient interface circuit is combined with medicated aerosol to deliver continuous high-frequency oscillation therapy. Fixed open apertures in the patient interface circuit allow ingress and egress of flow, and are calibrated to allow exhalation and prevent stacking of successive breaths.

Abstract: Disclosed are methods for determining the smoothness index of the interior of a metered dose container.

Abstract: A humidifier is provided including a first humidifier part, a second humidifier part connectable with the first humidifier part, and a sealing gasket disposed between the first and second humidifier parts. The second humidifier part is configured to hold a volume of liquid therein and the first and second humidifier parts and the sealing gasket define first and second internal passages within the humidifier. The first passage is disposed so as to be exposed to a surface of the volume of liquid and the second passage is isolated from at least one of the first passage and the surface of the volume of liquid. The second passage is configured to communicate with a pressure and/or sound sensing device.

Abstract: A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fixed diverter and a movable fluid orifice or fluid pathway connected with an actuator for responding to an inhalation or a manual actuation and beginning the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid orifice or fluid pathway connected to an actuator so that the fluid orifice or fluid pathway reaches a nebulizing position during inhalation.

Abstract: An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler.

Abstract: A flashlight for dispensing a substance from an aerosol canister includes an elongated housing having a front end, a rear end, and a central longitudinal axis, the aerosol canister being slidably received within the housing. The flashlight also includes at least one light emitting diode disposed approximate the front end of the housing and an elongated spray tube having a proximal end and a distal end, the proximal end being connected to the aerosol canister and the spray tube extending parallel to the central longitudinal axis such that the distal end extends beyond the front end of the housing.

Abstract: A refillable medical device comprising a base unit (4) adapted to be engaged with a refill unit (2), the device comprising means for counting the number of different refill units which are engaged with the base unit (4). The device may be in the form of a dry powder or pressurised aerosol inhaler, needleless injector, intravenous drip system etc. The device may comprise means to disable the device after a predetermined number of refill units have been used with the base.

Abstract: An apparatus and method for providing a nebula or aerosol to a patient. In one aspect, a nebulizer is pressure sensitive so that nebulization is coordinated with a breathing cycle of the patient. The nebulizer includes a movable gas diverter that diverts pressurized gas across a liquid outlet. The diverter is moved in response to the patient's breathing cycle. In one aspect, a biasing member moves the diverter. According to another aspect of the nebulizer, an annular liquid orifice disperses an aerosol in a radial direction in response to a pressurized gas flow from an orifice located concentrically thereto. Multiple liquid orifices may be provided. In a further aspect of the nebulizer, a reservoir includes an upper, wide portion and a lower narrow portion to apply relatively uniform pressure at a liquid orifice.

Abstract: The present invention is generally directed to a respiratory delivery system (e.g. an inhaler) used to discharge an appropriate substance therefrom for inhalation by a user. The respiratory delivery system generally has at least one airflow inlet, at least one outlet (e.g., mouthpiece, nasal mask), at least one airflow passage extending therebetween, and at least one ejection actuator for discharging an appropriate substance into the airflow. The respiratory delivery system also generally includes an airflow regulation assembly that can adjust the size of a passage through which substantially all of the airflow is directed to achieve/maintain a certain flow rate through the inhaler.

Abstract: A flashlight for dispensing a substance from an aerosol canister, the flashlight including an elongated housing having a front end, a rear end, and a central longitudinal axis, the aerosol canister being slidably received and fixedly positionable within the housing. At least one light emitting diode disposed approximate the front end of the housing and an elongated spray tube having a proximal end and a distal end, the proximal end being connected to the aerosol canister and the spray tube extending parallel to the central longitudinal axis such that the distal end extends beyond the front end of the housing.

Abstract: A drug delivery device and method is disclosed which produces aerosolized particles of pharmaceutically active drug for delivery to a patient by inhalation. The device is comprised of a liquid feeding source such as a channel to which formulation is added at one end and expelled through an exit opening. The feeding channel is surrounded by a pressurized chamber into which gas is fed and out of which gas is expelled from an opening. The opening from which the gas is expelled is positioned directly in front of the flow path of liquid expelled from the feeding channel. Various parameters are adjusted so that pressurized gas surrounds liquid flowing out of the feeding channel in a manner so as to maintain a stable capillary microjet of liquid until the liquid exits the pressure chamber opening and is aerosolized. The aerosolized particles having a uniform diameter in the range of about 1 to 5 microns are inhaled into a patient's lungs and thereafter reach the patient's circulatory system.

Abstract: The invention relates to an aerosol generator that comprises an oscillating membrane that is provided with openings. The aerosol generator is further characterized in that the liquid container is impinged upon with negative pressure by displacing a sealing element using a slidable sleeve and a rotary sleeve.

Abstract: A method of cleaning a metered dose spray device, and a cleaning composition for such cleaning, prevent the device from becoming clogged with medication. The method includes removing the aerosol can containing the medication from the actuator, placing an aerosol can containing a cleaning composition in the actuator, and dispensing the cleaning solution through the actuator. The residual medication is thereby removed from the actuator. A sufficiently small quantity of cleaning composition remains in the actuator so that the cleaning composition itself will not clog the actuator. Additionally, the cleaning composition is non-toxic, so that residual cleaning composition remaining in the actuator will not harm the user when a subsequent dose of medication is dispensed.

Abstract: A spacer assembly for a ventilator or other respiratory equipment for dispensing aerosol drugs from metered dose inhaler (MDI) canisters or nebulized drugs from a nebulizer into a respiratory gas stream delivered from a ventilator or other respiratory equipment connected to a patient. The improvements involve optimizing the shape of the spacer assembly body member and providing an efficient MDI nozzle assembly to allow maximal evaporation of the propellant before the propellant droplets impact the walls of the body member while providing a compact volume for directing the output of an MDI canister or a nebulizer into the gas stream.

Abstract: There is provided a housing for a dispenser suitable for dispensing medicament, particularly for use in the treatment of respiratory disorders. The housing comprises a body; said body including a support for receipt of said aerosol container; a first outlet port connectable to a first pressure recorder for recording change of pressure on firing of said aerosol container; and a second outlet port connectable to a second pressure recorder for recording air pressure within the body; wherein said first outlet port and said second outlet port are separate such that the change of pressure on firing and the air pressure within the body are individually recordable.

Abstract: The methods and devices disclosed provides for the delivery of agents to an orifice cavity and subsequent aspiration of the agent and orifice contents from the orifice cavity and related areas. In one form, the delivery and aspiration system comprises an agent delivery sub-assembly, an aspiration sub-assembly and a device tip sub-assembly. The subassemblies operate to first deliver an agent contained within the device to an orifice cavity and after an optional time delay, subsequently aspirate the delivered agent and orifice contents from the orifice cavity and related areas. In another form, a removable reservoir is provided whereby the aspirated agent and orifice contents from the orifice are assayed either independent of or within the device itself.

Abstract: This invention is a device (10) for inspiration of a mist from a nebulizer, having an inlet connector (12, 32) adapted to engage an outlet port of a nebulizer, a hollow mouthpiece element (126 34) for insertion into a patient's mouth; a conduit (14) forming a fluid connection between the inlet connector, and the hollow mouthpiece element. An exhaust valve (26) is provided for removing expiratory gases which are exhaled into the mouthpiece element to the ambient atmosphere via an exhaust/positive expiratory pressure (PEP) valve (26, 50). The PEP valve is positioned on the conduit between the inlet connector, and the mouthpiece element; and a filter housing (44) containing a filter (60) for filtering the exhaled gases passing from the exhaust/PEP valve.

Abstract: A pneumatic nebulizer for the delivery of medications that produces aerosol mist in a downward direction. A gas inlet introduces a high velocity gas that passes through a venturi orifice producing a venture effect. A liquid stored in a reservoir is drawn into the orifice, atomizing forming droplets. The droplets are further atomized by hitting a baffle. The mist formed substantially circumscribes the baffle.

Abstract: A medication inhalation therapy apparatus designed for the delivery of finely misted medicines to a patient in conjunction with the inhalation of 100% oxygen by the patient. The apparatus comprises a facemask equipped with an oxygen port for delivering oxygen, the facemask placed about or on the face of the patient. The facemask has a nebulizer mechanism disposed thereon, which is used to deliver medication in addition to oxygen. The nebulizer mechanism comprises a nebulizer port, which rotates 90 degrees in either direction to allow the present invention to be used in various angles. The nebulizer port is adapted to receive a nebulizer head, wherein are placed inhaleable medications, which are nebulized. When the apparatus is used for medication inhalation therapy, the nebulizer head receives oxygen for nebulizing inhaleable medications placed therein, the oxygen received from an oxygen port, which delivers oxygen to the facemask.

Abstract: A suction device capable of spraying a liquid medicine or the like so that the particles have a set uniform diameter.

Abstract: A pulmonary dosing system and method for supplying to a patient a predetermined amount of respirable therapeutically active material. The system comprises a patient interface to introduce the material into the patient's lungs. The patient interface is connected to a flexible inhalation tube and a flexible exhalation tube. The exhalation tube is connected to a filter having an outlet connected to atmosphere. The inhalation tube is connected to an apparatus for providing pulsed amounts of the material entrained in filtered atmospheric air. A control unit operates the pulmonary dosing system in accordance with operator inputs regarding the number of patent exhales between pulses, and pulse length. The exhaust filter and the apparatus for providing pulsed amounts of the therapeutically active material may be enclosed in a containment case and the patient's interface may comprise a mouth tube-mask combination when the therapeutically active material comprises at least one toxic drug.

Abstract: The nebulizer vial for aerosol therapy comprising a tube fed at a first end with compressed air, the tube being constricted at its second end prior to the relative exit orifice to obtain a venturi effect. The orifice of the tube emerges from the free surface of a solution of an aerosol therapy medicament, a nozzle being concentrically mounted on the second end of the tube such that between the tube and nozzle there remains an interspace communicating with the solution. A flow breaker device is provided above the orifice of the nozzle. The vial is provided with an exit for the formed aerosol and an inlet for entry of external air as a result of suction exerted by the patient on the exit. For diameter parity of the orifice of the nozzle, elements are provided to vary the distance between the nozzle orifice and the flow breaker device.

Abstract: An apparatus and method for providing a nebula or aerosol to a patient. In one aspect, a nebulizer is pressure sensitive so that nebulization is coordinated with a breathing cycle of the patient. The nebulizer includes a movable gas diverter that diverts pressurized gas across a liquid outlet. The diverter is moved in response to the patient's breathing cycle. In one aspect, a biasing member moves the diverter. According to another aspect of the nebulizer, an annular liquid orifice disperses an aerosol in a radial direction in response to a pressurized gas flow from an orifice located concentrically thereto. Multiple liquid orifices may be provided. In a further aspect of the nebulizer, a reservoir includes an upper, wide portion and a lower narrow portion to apply relatively uniform pressure at a liquid orifice.

Abstract: A hand-held breathing device for use by patients having respiratory problems creates a sealed backpressure in the airways of the patient by creating resistance to exhalation. A peep valve is mounted inside a hollow body, and a pre-set compression spring is mounted between the valve and an adjustable cap or cam lever in the main body of the device. A pair of valve openings extend through the wall of the main body, one opening serving as an intake port for inhaling of air by the patient and the second port—for exhalation of carbon dioxide. An intake valve is mounted inside the body between a normally open end of the device and the exhalation valve. In one of the embodiments, the device is attached to a nebulizer to facilitate buildup of positive pressure and delivery of medication to the patients' lungs.

Abstract: An apparatus and method for providing a nebula or aerosol to a patient. In one aspect, a nebulizer is pressure sensitive so that nebulization is coordinated with a breathing cycle of the patient. The nebulizer includes a movable gas diverter that diverts pressurized gas across a liquid outlet. The diverter is moved in response to the patient's breathing cycle. In one aspect, a biasing member moves the diverter. According to another aspect of the nebulizer, an annular liquid orifice disperses an aerosol in a radial direction in response to a pressurized gas flow from an orifice located concentrically thereto. Multiple liquid orifices may be provided. In a further aspect of the nebulizer, a reservoir includes an upper, wide portion and a lower narrow portion to apply relatively uniform pressure at a liquid orifice.

Abstract: An ultrasonic dosage device having an enclosure for providing a medication in the form of a nebulized mist, including an energy source positioned within the enclosure and a vibration device with a switch for applying electrical energy from the energy source to the vibration device. An assembly is attached to the enclosure and has a membrane disposed between the vibration device and the medication for containing the medication and maintaining the medication in contact with the vibration device only by way of the membrane, whereby the membrane is vibrated and the medication is thereby converted into the mist by vibrations transmitted to the medication by way of the membrane when power is applied to the vibration device.

Abstract: Nebulizer pump adapters allow the attachment of a bicycle pump to a nebulizer when a source of compressed air is not otherwise available. In order for a nebulizer to work, there must be a source of gas flow sufficient to nebulize the solution. The compressed gas tank or electrical air compressor that is normally used may not be available in certain situations, such as in the wilderness or during a blackout. As a result, having the option of using a hand-operated pump may be critical in administering inhaled aerosol medications.

Abstract: An improved medical mechanical compressor nebulizer for atomizing liquid inhalation dose to achieve therapeutic effect comprises a body, an air compression device located in the body, a safety switch which is serially connected to voltage is located at the surrounding of the air compression device and an atomization device connecting to the air compression device and an output device. The atomization device is precisely and securely fastened to the air compression device by a screwing mechanism, not only for connection of air passage, but also for forming a coupled air chamber which serves as a buffer to attain more stabilized ejecting air, reduce noise and achieve improved atomization effect. Also, the above screwing design can prevent unwarranted power consumption if the apparatus is inadvertently activated by the user.

Abstract: A pulmonary drug delivery device includes a hand piece that is electrically connected to a control unit. A cartridge is engagable with the hand piece and includes a drug reservoir, a pump connected to the drug reservoir, an electrically chargeable nozzle connected to the pump, a discharge electrode, and an information storage element. The control unit controls the pump and the electrical charge of the nozzle and discharge electrode in accordance with instructions stored within the information storage element.

Abstract: A drug delivery device and method is disclosed which produces aerosolized particles of pharmaceutically active drug for delivery to a patient by inhalation. The device is comprised of a liquid feeding source such as a channel to which formulation is added at one end and expelled through an exit opening. The feeding channel is surrounded by a pressurized chamber into which gas is fed and out of which gas is expelled from an opening. The opening from which the gas is expelled is positioned directly in front of the flow path of liquid expelled from the feeding channel. Various parameters are adjusted so that pressurized gas surrounds liquid flowing out of the feeding channel in a manner so as to maintain a stable capillary microjet of liquid until the liquid exits the pressure chamber opening and is aerosolized. The aerosolized particles having a uniform diameter in the range of about 1 to 5 microns are inhaled into a patient's lungs and thereafter reach the patient's circulatory system.

Abstract: An apparatus (1) for nebulising a liquid, in particular for medical use, comprises a box case (2) and a compressor assembly (4) housed internally to the box case (2) and provided with an air intake conduit (5) and an air delivery conduit (6). A device (10) for activating the compressor assembly (4) is housed internally to the box case (2) and is provided with an external command (16) which can be activated by the user. A nebulising bulb (17) is housed in the box case (2), presents a terminal mouthpiece (18) and is provided with an air inlet section placed directly in communication with the delivery conduit (6) of the compressor assembly (4).

Abstract: A combination spirometer or peak flow meter and nebulizer system is provided. Utilization of common elements, on a time sharing basis is accomplished by the combined instrumentation. The sharing of a common chamber by a peak flow meter and a nebulizer system is controlled by valves operated in response to phases of the respiratory process of a patient. With this combination vaporized medication is provided to a patient for inhalation during the inhale phase of the respiration cycle and the effectiveness of the inhaled medication is monitored by measuring the rate of flow of the breath exhaled during the exhale phase of the same respiratory cycle.

Abstract: A hand-held breathing device for use by patients having respiratory problems creates a sealed backpressure in the airways of the patient by creating resistance to exhalation. A peep valve is mounted inside a hollow body, and a pre-set compression spring is mounted between the valve and an adjustable cap or cam lever in the main body of the device. A pair of valve openings extend through the wall of the main body, one opening serving as an intake port for inhaling of air by the patient and the second port—for exhalation of carbon dioxide. An intake valve is mounted inside the body between a normally open end of the device and the exhalation valve. In one of the embodiments, the device is attached to a nebulizer to facilitate buildup of positive pressure and delivery of medication to the patients' lungs.

Abstract: An apparatus and method for providing a nebula or aerosol to a patient. In one aspect, a nebulizer is pressure sensitive so that nebulization is coordinated with a breathing cycle of the patient. The nebulizer includes a movable gas diverter that diverts pressurized gas across a liquid outlet. The diverter is moved in response to the patient's breathing cycle. In one aspect, a biasing member moves the diverter. According to another aspect of the nebulizer, an annular liquid orifice disperses an aerosol in a radial direction in response to a pressurized gas flow from an orifice located concentrically thereto. Multiple liquid orifices may be provided. In a further aspect of the nebulizer, a reservoir includes an upper, wide portion and a lower narrow portion to apply relatively uniform pressure at a liquid orifice.

Abstract: A nasal inhaler for introducing a substance to a nasal cavity of a user. The nasal inhaler comprises a chamber having an interior and an exterior, an outlet comprising an air exit passageway in flow communication with the interior of the chamber, a one-way air inlet valve in one-way flow communication with the interior of the chamber, and a dosage inlet passageway in flow communication with the interior of the chamber. A container includes a dispensing portion disposed in the dosage inlet passageway. In preferred embodiment, an adapter defines the dosage inlet passageway and is connected to the chamber. A mask also can be connected to the outlet. A method for dispensing a substance into the nasal cavity of the user comprises inserting the outlet into the nasal cavity, dispensing the substance into the chamber and inhaling through the outlet. A method for assembling a nasal inhaler assembly also is provided.

Abstract: The present invention relates to a nebulizer comprising an electrically energizable ultrasonic transducer having an oscillation frequency dependent current and voltage characteristic exhibiting the occurrence of a minimum magnitude of current through the transducer at an anti-resonance frequency of the transducer, the voltage across the transducer increasing with an increase in frequency within a range of frequencies including said anti-resonance frequency. The nebulizer further comprises a transducer drive system for generating a drive signal for energising the transducer, the drive system comprising oscillation frequency control means operable to maintain the frequency of the drive signal at a specific frequency within said range of frequencies by reference to the variation of both current through the transducer and voltage across the transducer with a change of frequency within the said frequency range.

Abstract: The invention provides a novel method of treating respiratory diseases, e.g., pediatric asthma, in a continuing regimen with not more than one daily dose of the drug budesonide using a nebulizer.

Abstract: An endotracheal tube can be inserted into a patient's trachea during resuscitation by using a face mask and a curved guide. The guide is inserted through a flexible port in the face mask and has a curved distal portion that extends into the patient's mouth and hypopharynx. The patient is initially resuscitated by supplying a flow of air/oxygen through the mask. For example, a resuscitation bag can be connected to a rotatable ventilation port on the face mask. Alternatively, a resuscitation attachment with an air filter and one-way valve can be removably attached to the ventilation port of the face mask to enable a health care provider to directly resuscitate the patient. An endotracheal tube is inserted over the distal end of a fiber optic probe.

Abstract: A hand-held compressor nebulizer suitable for vaporizing liquid medication, comprising a casing and a motor-driven air pump. The nebulizer includes a liquid medication supply unit and a vaporizing unit. The vaporizing unit comprises upper and lower vaporizing chambers, the lower chamber including a reservoir for liquid medication from the liquid medication supply unit. The vaporizing unit includes a hollow conical member located within the lower chamber and defining an internal conical passage having a relatively smaller upper end and a relatively larger lower end, the lower end being in communication with the air pump for receiving an upward airflow produced by the air pump. The airflow increases in speed in the upward direction and creates a negative pressure upon exit from the upper end of the conical passage. The vaporizing unit further includes a vaporizing jacket having a tapered interior and disposed around the conical member to form a narrow gap with the conical member.

Abstract: An aerosolization device comprises a housing having an inlet and an outlet and an airway extending from the inlet to the outlet. A valve in the airway comprises a piezoelectric element which controls the valve, and a reservoir in communication with the airway is adapted to contain a pharmaceutical formulation so that the pharmaceutical formulation may be introduced into the airway and passed through the outlet in an aerosolized form. The piezoelectric element may alternatively or additionally be used to sense a condition in the aerosolization device.

Abstract: An apparatus for delivery of a medicament to the respiratory system comprises a reservoir that is adapted to hold a liquid medicament that is to be delivered to a respiratory system. An aerosol generator is provided that is adapted to aerosolize the liquid medicament. A liquid supplier is used to deliver the liquid medicament from the reservoir to the aerosol generator. A connector is operably coupled to the aerosol generator and comprises a gas conduit having an inlet, and an outlet, and an aerosol supply conduit. The aerosol generator is configured to provide the aerosolized liquid medicament into the gas conduit through the aerosol supply conduit, and the gas conduit is adapted to pass gases to entrain the aerosolized liquid medicament.

Abstract: The improved medical nebulization device includes a head and a removeable depending liquid reservoir. The head has a closed top, closed sides and open bottom defining a central space in which is secured a nebulization chamber having closed sides and an open top and open bottom. A nebulization baffle is connected to the head top and extends into the nebulization chamber. A liquid draw tube is connected to the baffle and depends from the chamber into the reservoir. A nebulized aerosol output port extends between the space outside the chamber and a point peripheral of the head for supplying nebulized aerosol to a patient. An auxiliary multiple gas entrainment inlet port, with removeable cap, extends into the chamber at a point remote from the output port and is adapted to supply auxiliary gases such as a mixture of oxygen and helium. The liquid reservoir in one embodiment includes a graduated liquid measuring scale and is transparent.