Gas Stream Aspirating Medicament From Reservoir Patents (Class 128/200.21)
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Publication number: 20110290268Abstract: An aerosol generator device has an elongate body with an interior passageway extending longitudinally to its mouth end. The device receives an interchangeable, pressurised canister charged with a nicotine containing liquid that is discharged in a metered dose on manual actuation of a button member that causes a valve in the canister to open and discharge through a discharge tube. A sleeve releaseably couples the canister to the body. The button member is slidably mounted on the body for reciprocal movement along a trigger axis Y-Y? extending transversely of the longitudinal axis X-X? of the device, and has a manually depressible surface portion and a camming surface portion that drives a slidable nozzle member to press the discharge tube inwardly of the canister to open its valve and release liquid into the nozzle member. Nozzle forms an aerosol from the liquid, which is delivered to the consumer through outlets in the mouth end of the device.Type: ApplicationFiled: May 25, 2010Publication date: December 1, 2011Inventor: Steven Michael Schennum
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Publication number: 20110283996Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The delivery system includes a plunger assembly having a pair of converging blades coming to a point for piercing a medication capsule held within a docking chamber adjacent to a nebulizing mixing chamber and a hollow needle connected to an air power source directing air through said needle, to force liquid medication from said pierced medication capsule into said nebulizing mixing chamber of said nebulizer.Type: ApplicationFiled: June 30, 2011Publication date: November 24, 2011Inventor: Robert Abrams
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Patent number: 8061352Abstract: An apparatus and method for indicating breathing cycle of a patient using an aerosol delivery device. In one aspect, an aerosol delivery device includes a visual indicator that is moveable in response to a patient's breathing cycle and is positioned away from an inspiration path of the aerosol. In another aspect, a method of cycling a visual indicator between a first position and a second position in response to a patient's breathing cycle is described.Type: GrantFiled: May 8, 2007Date of Patent: November 22, 2011Assignee: Trudell Medical InternationalInventors: Jerry R. Grychowski, George Baran, Martin P. Foley
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Patent number: 8061350Abstract: A process and a device for dosing a pharmaceutical agent, preferably a liquid, are proposed. To achieve an enhanced dosing accuracy, a first component that is produced in batches, such as a shaped seal, is combined with a second component, such as a guide pipe selected from a suitable group guide pipes, wherein the suitable group of second components is selected based on at least one decisively significant value of the respective batch first components and is distinguished by an essential value of the second component which will optimize the sealing between the first and second components.Type: GrantFiled: June 2, 2006Date of Patent: November 22, 2011Assignee: Boehringer Ingelheim Pharma GmbH & Co. KGInventors: Georg Boeck, Johannes Geser, Matthias Hausmann, Hans-Juergen Koelbel, Joachim Eicher, Christian Feiertag
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Publication number: 20110277754Abstract: A breathing system is provided that employs a reservoir for holding oxygen or an oxygen and medicine mixture while the patient is not inhaling. The reservoir generally prevents waste and reduces cost and helps prevent the patient from re-inhaling the previously exhaled gases.Type: ApplicationFiled: July 22, 2011Publication date: November 17, 2011Applicant: WESTMED, INC.Inventors: Robert J. McKinnon, James Dale Bickley
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Publication number: 20110265787Abstract: A nebulizer and a method of breathing using the nebulizer is described. The nebulizer and breathing techniques are capable of delivering medicament into the sinus cavity of a user.Type: ApplicationFiled: December 3, 2010Publication date: November 3, 2011Applicant: Kurve Technology, Inc.Inventor: Marc Giroux
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Patent number: 8015969Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. The delivery system includes a pressure burstable seal at one end of the capsule, which is burst by the application of force against the opposite end of the capsule.Type: GrantFiled: April 13, 2010Date of Patent: September 13, 2011Inventor: Robert Abrams
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Patent number: 8001963Abstract: Particular aspects provide a novel integrated nebulizer and particle dispersion chamber (12), and novel methods of using same. Preferably, the particle dispersion chamber (12) provides for delivery of a vortical flow of nebulized particles to the nostrils. The inventive integrated nebulizer, delivery methods and breathing techniques allow for delivering medicament into the deep nasal cavity and paranasal sinuses of a user. Significantly, the inventive devices and methods allow for systemic and topical delivery of medicaments via the membranes of the nasal cavity and paranasal sinuses. Additional preferred embodiments provide complementary cartridge docking system that allows for user-specific nebulized drug delivery.Type: GrantFiled: September 3, 2004Date of Patent: August 23, 2011Assignee: Kurve Technology, Inc.Inventor: Marc Giroux
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Patent number: 7997265Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. The delivery system includes a pressure burstable seal at one end of the capsule, which is burst by the application of force against the opposite end of the capsule.Type: GrantFiled: February 8, 2011Date of Patent: August 16, 2011Inventor: Robert Abrams
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Patent number: 7984830Abstract: A fluid dispenser device has a reservoir, a pump, a dispensing outlet, an actuator, and a removable cap. The actuator is integrally formed with the dispensing outlet in at least one embodiment. The cap has detents that project from the cap. The actuator is blocked from actuating by a blocking flange that is integrally connected with the dispensing outlet. The detents from the cap bend the blocking flange so that the reservoir can not move in relation to the dispensing outlet when the cap is in a closed position. When the cap is removed, the detents no longer bend the blocking flange, and the actuator can then move the reservoir in relation to the dispensing outlet and affect dispensation. In at least one embodiment the actuator is not axially aligned with the dispensing outlet.Type: GrantFiled: February 20, 2006Date of Patent: July 26, 2011Assignee: Tebro S.A.Inventor: Giuseppe Stradella
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Publication number: 20110168171Abstract: A nebulizer capable of supplying oxygen gas of high concentration by increasing the flow rate of the oxygen gas and capable of forming minute aerosol irrespective of a change in the flow rate of the oxygen gas. A nebulizer (A) has a nozzle member (11) for discharging oxygen gas from an orifice (11b), an aerosol forming member (12) mounted at a position corresponding to the orifice, sucking water by suction created by flow of the oxygen gas discharged from the orifice, and forming the sucked water into minute aerosol, and a window (9) and a slit (10) which suck air as the oxygen gas is discharged from the orifice of the nozzle member. The nozzle member (11) has, in addition to the orifice (11b), an oxygen gas outflow section formed in a direction different from that of the orifice and causing supplied oxygen gas to flow thereout according to the pressure of the oxygen gas.Type: ApplicationFiled: March 12, 2009Publication date: July 14, 2011Applicants: Gunma Koike Co., Ltd., Koike Medical Co., Ltd.Inventors: Toshi Tsuboko, Eiichi Takano, Ise Satomi
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Publication number: 20110132354Abstract: The present invention provides a method of treating neoplasms of the nasal cavity. Fluid containing corticosteroids held in a canister is atomized via a compressed air supply to create particles sized for penetration and retention in the nasal cavity under pressure that is able to stent open the soft tissues of the nose to deliver the resultant mist into the whole of the nasal passages without the need for the patient to create an airstream through inhalation. The device consists of a main canister with a reservoir to hold the fluid, two air outlets and an insert that is placed over the air outlets, the insert having at least one outlet that is larger than the holes in the air outlet and allows the fluid to be atomized and injected directly into the nasal cavity.Type: ApplicationFiled: May 26, 2010Publication date: June 9, 2011Inventors: William J. Flickinger, John Quackenbush
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Publication number: 20110137290Abstract: The present invention provides a method and device for nasal irrigation and drug delivery wherein fluid held in a canister is atomized via a compressed air supply to create particles sized for penetration and retention in the nasal cavity under pressure that is able to stent open the soft tissues of the nose to deliver the resultant mist into the whole of the nasal passages without the need for the patient to create an airstream through inhalation. The device consists of a main canister with a reservoir to hold the fluid, two air outlets and an insert that is placed over the air outlets, the insert having at least one outlet that is larger than the holes in the air outlet and allows the fluid to be atomized and injected directly into the nasal cavity.Type: ApplicationFiled: December 8, 2009Publication date: June 9, 2011Inventors: William J. Flickinger, John Quackenbush
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Patent number: 7954487Abstract: A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer, in one embodiment, includes a fluid channel air inlet and fluid channel air inlet valve responsive to either a manual force external of the nebulizer, or a patient's breathing, to begin the nebulization process. The nebulizer also includes a fluid return channel to a fluid source, such as a removable vial, containing fluid to be aerosolized.Type: GrantFiled: August 10, 2007Date of Patent: June 7, 2011Assignee: Trudell Medical InternationalInventors: Jerry Grychowski, Martin P. Foley, Michael Nuttall
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Publication number: 20110114088Abstract: An inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. A flexible guiding element (20) receives the used blisters strip.Type: ApplicationFiled: January 19, 2009Publication date: May 19, 2011Inventors: Stephen William Eason, Matthew Neil Sarkar, Graham Roger Gibbins, Ralf Thoemmes, Jessica Frentzel-Beyme, Jens Besseler, Timo Von Brunn
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Publication number: 20110105936Abstract: In accordance with non-limiting examples, a nebulizer includes a main body comprising an air channel section and further comprising a mixing chamber and a venturi positioned to be placed within the patient's oral cavity and configured to receive medicine and air and mix the medicine and air within the mixing chamber and receive the air flow through the venturi and cause the medicine entering the mixing chamber to be atomized by the action of air flowing through the venturi. An air flow sensor is associated with the main body and configured to measure the air flow created by the patient's one of at least inhaling and exhaling air.Type: ApplicationFiled: January 6, 2011Publication date: May 5, 2011Applicant: Pneumoflex Systems, LLCInventors: W. Robert ADDINGTON, Stuart P. MILLER, Michael M. PHELIPA, Robert E. STEPHENS
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Publication number: 20110094507Abstract: A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises an impaction element (31) onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device (35) for better de-agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.Type: ApplicationFiled: December 29, 2008Publication date: April 28, 2011Applicants: Vectura Delivery Devices Limited, Boehringer Ingelheim GmbH, CD PatentsInventors: Herbert Wachtel, Quentin John Harmer, Matthew Neil Sarkar, Ivan Milivojevic
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Publication number: 20110083665Abstract: A multi-access adapter operable to dispense doses of a medicament in succession from a bulk container, such as a vial. A preferred adapter may be used alone, or in combination with various discharge devices. A first preferred combination includes the adapter paired with a needle for injection of the medicament into one or more patients. A second preferred combination includes an atomizing nozzle affixed to the adapter and arranged for discharge of the medicament therethrough. Sometimes the atomizing nozzle carries a nostril guide structure that can be absorbent and may operate as a splash guard.Type: ApplicationFiled: December 13, 2010Publication date: April 14, 2011Inventors: Marshall T. Denton, Timothy R. Wolfe, Mark A. Christensen
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Patent number: 7905229Abstract: Particular aspects provide novel atomizers for generating particles over a broad range of MMAD size distributions, the eliminating the requirement for an impaction baffle in generating the desired particle sizes. In particular aspects, the atomization means communicates with a remote particle filter member configured and positioned to provide for particle size filtering. In additional aspects, the atomization means communicates with a particle dispersion chamber suitable to impart a desired particle flow pattern to particles within and exiting the dispersion chamber. In further aspects, the atomization means communicates with a nasal, ocular, oral or ‘vicinity’ adapter. The novel devices provide for targeted (e.g., nasal, ocular, oral, local vicinity), systemic, and/or topical delivery of an atomized liquid (e.g., via the nasal cavity, olfactory region, and mouth). Further exemplary aspects relate to aerosolization and delivery of perfume, fragrance, essential oil or cosmeceutical agents and the like.Type: GrantFiled: August 30, 2007Date of Patent: March 15, 2011Assignee: Kurve Technology, Inc.Inventors: Marc Giroux, William A. DeGroodt, Joseph R. Pearce, Robert W. Kamp, Finn O. Rinne, Paul C. Leung
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Publication number: 20110041841Abstract: A passive inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. The inhaler has a flow resistance of at least 75000 Pa1/2s/m3.Type: ApplicationFiled: January 19, 2009Publication date: February 24, 2011Applicants: Vectura Delivery Devices Limited, Boehringer Ingelheim GmbH, CD PatentsInventors: Herbert Wachtel, Quentin John Harmer, Stephen William Eason
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Patent number: 7878194Abstract: An inhaler has a cap body for defining a flow path and having first and second air inhalation openings for introducing outside air into the flow path from the outside; an air inhalation valve for opening and closing the first air inhalation opening by using the difference in pressure between the flow path and the outside; and a shielding section capable of selectively shielding either of the first and second air inhalation openings. The inhaler is configured to be switchable between two states that are a first state where the second air inhalation opening is shielded by the shielding section and outside air can be introduced through the first air inhalation opening by using the pressure difference and a second state where the first air inhalation opening is shielded by the shielding section and communication between the flow path and the outside through the second air inhalation opening is constantly maintained.Type: GrantFiled: March 10, 2006Date of Patent: February 1, 2011Assignee: Omron Healthcare Co., Ltd.Inventors: Takehiro Hamaguchi, Makoto Tabata, Satoshi Kurata, Yoshihiro Nakatsuji
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Patent number: 7878418Abstract: An atomizer provides a control of duty cycle or a motor driving a diaphragm pump. By providing precise, high-speed flow through an eductor nozzle, improved atomization occurs. However, to control the total volume of atomized liquid discharged, the delay time between operational time periods may also be controlled. Thus, a very effective atomizer provides economical use of essential oils by control duty cycle. Precision modeling provides highly integrated subsystems providing superior performance and reliability.Type: GrantFiled: October 8, 2008Date of Patent: February 1, 2011Inventor: Early Vaughn Sevy
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Publication number: 20110017205Abstract: A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises a metallic piercing member (7) with two piercing elements (25) extending parallel to each other and inclined to a lid (27) of a blister pocket to be punctured.Type: ApplicationFiled: January 23, 2009Publication date: January 27, 2011Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Herbert Wachtel, Andree Jung
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Patent number: 7849853Abstract: A ventilator circuit for use in administering medication to a patient includes a chamber housing defining an interior space and having an input end and an output end and a one-way inhalation valve positioned upstream of the interior space. The one-way inhalation valve is operative to permit a flow of medication into the interior space of the chamber housing. An inhalation conduit communicates with the output end of the chamber and is adapted to transmit the medication to the patient. An exhaust conduit is connected to the inhalation conduit and a one-way exhaust valve is located in the exhaust conduit. The one-way exhaust valve is adapted to prevent a backflow of gas from the exhaust conduit into the inhalation conduit. A method of administering a medication to a patient is also provided.Type: GrantFiled: February 9, 2004Date of Patent: December 14, 2010Assignee: Trudell Medical InternationalInventors: Jerry R. Grychowski, Martin P. Foley, Michael S. Dunn
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Patent number: 7849851Abstract: A nebulizer having an insertable container and a monitoring device for counting actuations of the nebulizer is proposed. The monitoring device is mounted in a detachable housing part and directly detects movements of container during a nebulizing process, an air supply current in the region of a mouthpiece, and/or the production of aerosol, in order to detect this as the actual dispensing of fluid and actuation of the nebulizer, while preferably the time of actuation of the nebulizer is additionally detected and stored. This allows better monitoring and guidance for the user.Type: GrantFiled: February 24, 2005Date of Patent: December 14, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Bernd Zierenberg, Klaus Noehl, Johannes Geser, Gilbert Wuttke, Stefan Kaulmann, Hubert Kunze, Andreas Fiol
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Patent number: 7841335Abstract: Various embodiments of a breath-activated nebulizer with flow-based fluidic control and related methods of using such a nebulizer are disclosed. The nebulizer may include a body comprising a reservoir for holding medication, a nozzle for emitting a jet of pressurized gas, and a fluid conduit in communication with the reservoir for delivery of the medication proximate the jet to produce an aerosol of medication. The nebulizer may also include a nebulizer outlet in communication with the body for delivery of the aerosol to a patient, an entrainment passage for providing entrainment flow from atmosphere during inhalation by the patient, and a control conduit in fluid communication with the fluid conduit for delivery of a control gas to the fluid conduit to prevent the delivery of the medication proximate the jet. In some exemplary embodiments, the control conduit may comprise a gas passage proximate the entrainment passage to allow the control gas to flow across the entrainment passage.Type: GrantFiled: March 29, 2007Date of Patent: November 30, 2010Assignee: CareFusion 2200, Inc.Inventors: Steven M. Harrington, Douglas Gaylord, David A. Rivera, Neil A. Korneff, Rebecca A. Wilday, Chris Zollinger
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Patent number: 7841336Abstract: Various embodiments of a breath-activated nebulizer with fluidic control and related methods of using such a nebulizer are disclosed. The nebulizer may include a body comprising a reservoir for holding medication, a nozzle for emitting a jet of pressurized gas, and a fluid conduit in communication with the reservoir for delivery of the medication proximate the jet to produce an aerosol of medication. The nebulizer may also include a nebulizer outlet in communication with an interior of the body for delivery of the aerosol to a patient, a control conduit in fluid communication with the fluid conduit for delivery of a control gas to the fluid conduit to prevent the delivery of the medication proximate the jet, and a fluidic amplifier configured to control the delivery of the control gas to the control conduit.Type: GrantFiled: March 29, 2007Date of Patent: November 30, 2010Assignee: CareFusion 2200, Inc.Inventors: David A. Rivera, Steven M. Harrington, Bruce K. Bridges, Neil A. Korneff
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Patent number: 7836885Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system conveniently useable in an emergency to deliver the stored medication dose directly to the nebulizing chamber quickly, reliably, and with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication.Type: GrantFiled: July 3, 2008Date of Patent: November 23, 2010Inventor: Robert Abrams
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Publication number: 20100288271Abstract: The invention relates to a system for artificial respiration of persons, comprising: a respirator apparatus, comprising: a respirator device and at least one respiratory tube coupled to the respirator device, which respiratory tube is adapted to enable respiration of a person; and at least one atomizing device for atomizing an additive in an airflow to be inhaled by the persons, comprising: at least one atomized body coupled to the respiratory tube and at least one supply container for holding a supply of at least one additive.Type: ApplicationFiled: November 9, 2007Publication date: November 18, 2010Applicant: INDES HOLDING B.V.Inventors: Wilhelmus Petrus Johannes De Kruijf, Klaas Jacobus Blacquiere, Evert Jan Klip, Jeroen Mathijn Wissink, Marco Voogsgerd
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Publication number: 20100269818Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. The delivery system includes a pressure burstable seal at one end of the capsule, which is burst by the application of force against the opposite end of the capsule.Type: ApplicationFiled: April 13, 2010Publication date: October 28, 2010Inventor: Robert Abrams
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Patent number: 7814900Abstract: A dispenser (1) comprises a can (2) and body (3). The can is an aluminum extrusion with a valve crimped into its mouth, the valve having an outlet spout (4). The crimped region (5) of the can surrounding the valve has a lesser diameter than the can has through the main part (6) of its length. The body has a mouthpiece (11) with a pivotal cover (12) drivingly connected to a cam (13). This bears on the underside of junction member (14), into a socket (15) of which the spout 4 fits. A breath actuated dose release mechanism (16) is provided. The body has a tubular section (7) for receiving the necked down region (5) of the can. A printed paper label (21) is wrapped around the joint between the body and the can to unite the can to the body in position such that when the cover is opened, a dose is dispensed by the cam (13) lifting the junction member and depressing the spout.Type: GrantFiled: March 17, 2003Date of Patent: October 19, 2010Assignee: Clinical Designs LimitedInventor: Raymond John Bacon
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Patent number: 7814902Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. The delivery system includes a slicing blade to sever the capsule and a looped paddle follower to move the severed portion out of the way of fluid flow.Type: GrantFiled: January 26, 2009Date of Patent: October 19, 2010Inventor: Robert Abrams
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Patent number: 7803129Abstract: Described are a method and device for needleless injection of a liquid substance in the skin or other target tissue of a patient, in which droplets of the liquid substance are produced, and the droplets of liquid substance are directed toward the surface of the patient's skin or other target tissue at a velocity sufficiently high to inject the droplets of liquid substance in the patient's skin or other target tissue. The droplets of the liquid substance are accelerated toward the surface of the patient's skin or other target tissue in order to inject the accelerated droplets of liquid substance in the patient's skin or other target tissue.Type: GrantFiled: April 4, 2003Date of Patent: September 28, 2010Assignee: Societe de Commercialisation des Produits de la Recherche Appliquee-Socpra Sciences et Genie, S.E.C.Inventors: Martin Brouillette, Stephane Dufresne
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Publication number: 20100236546Abstract: An aerosol inhalation system has an inhalator (2) having an aerosol-generating passage (8) connecting an outside air inlet (6) and a mouthpiece (4) to each other, in which a part of the passage (8) is made up of a tubular electric heater (12); a flexible storage bag (14) prepared separately from the inhalator (2) and containing a solution that is a source of aerosol; and a feed pipette (16) connecting the bag (14) to the inhalator (2), in which the feed pipette (16) has a feed opening (20) opened in the passage (8) and disposed upstream of the heater (12), the solution in the bag (14) is sucked out of the feed opening (20) into the passage (8) and then transferred to the heater (12) with an intake airflow running towards the mouthpiece (4) when the user inhales, the sucked-out solution is heated by the heater (12) to be evaporated, and aerosol is thus generated in the intake airflow.Type: ApplicationFiled: May 28, 2010Publication date: September 23, 2010Inventors: Manabu YAMADA, Kazuhiko Katayama, Hiroshi Sasaki
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Patent number: 7784459Abstract: A conventional respiratory nebulizer has an emergency medication dose storage system conveniently useable in an emergency to deliver the stored medication dose directly to the nebulizing chamber quickly, reliably, and with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication.Type: GrantFiled: September 11, 2008Date of Patent: August 31, 2010Inventor: Robert Abrams
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Patent number: 7779831Abstract: A nebulizer includes a piezoelectric transducer for aerosolizing a drug solution in a disposable cup module disposed above the transducer. Acoustic waves generated by the transducer propagate sequentially through transmitting medium, a first barrier, coupling medium, and a second barrier that forms part of the cup module, and into the interior of the cup module. The transducer at least partially comprises silver. The silver fluidly contacts the transmitting medium to discourage bacteria growth in the transmitting medium. The device includes electronics components that drive the transducer and measure an electrical characteristic associated with the transducer during operation. The electronics components measure changes in the electrical characteristic to determine when the drug solution level falls below a predetermined threshold, and deactivates the device accordingly.Type: GrantFiled: April 19, 2007Date of Patent: August 24, 2010Assignee: RIC Investments, LLCInventors: Dirk Von Hollen, Eric A. Lieberman, Alexandru Bucur
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Publication number: 20100206305Abstract: A nebulizer includes a receptacle for containing a liquid, a liquid-drawing tube, and a hollow cover including a partition plate dividing an interior of the cover into first and second chambers, first and second conduits each having an inlet end adapted to be connected to a compressed gas supply tube, and an outlet end communicated with the first chamber, and a mist output tube communicating fluidly with the second chamber. A nebulizing unit is connected to the outlet end of the first conduit and the liquid-drawing tube for directing a first compressed gas from the first conduit to the liquid exiting from the tube to convert the liquid into a mist. The second conduit introduces into the first chamber a second compressed gas which entrains the mist when flowing to the second chamber and exiting through the mist output tube.Type: ApplicationFiled: September 17, 2009Publication date: August 19, 2010Applicant: Galemed CorporationInventors: Gary C. J. Lee, Yu-Chien Yen, Thomas Loescher
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Publication number: 20100199982Abstract: A fluid flow control valve comprises (a) a high pressure region adapted to contain a fluid at its supercritical or nearcritical temperature and pressure conditions and connected via an orifice to a low pressure region, (b) a seat adjacent the orifice, (c) a sealing element positionable against the seat to form a seal between the high pressure region and the low pressure region, and (d) an electrically and/or electronically controlled actuator operable to move the sealing element against and/or away from the seat to allow control of fluid flow from the high pressure region to the low pressure region. In a specific embodiment, the high pressure region contains a fluid at its supercritical or nearcritical temperature and pressure conditions. The valve may be used, for example, to provide very low flow rates, for example, for supercritical fluid chromatography, supercritical fluid extraction, critical point drying, supercritical fluid cleaning, and supercritical fluid separation methods.Type: ApplicationFiled: February 10, 2010Publication date: August 12, 2010Inventor: Brian N. Hansen
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Publication number: 20100204602Abstract: In accordance with non-limiting examples, a nebulizer includes a main body comprising an air channel section and further comprising a mixing chamber and a venturi positioned to be placed within the patient's oral cavity and configured to receive medicine and air and mix the medicine and air within the mixing chamber and receive the air flow through the venturi and cause the medicine entering the mixing chamber to be atomized by the action of air flowing through the venturi. An air flow sensor is associated with the main body and configured to measure the air flow created by the patient's one of at least inhaling and exhaling air.Type: ApplicationFiled: March 16, 2010Publication date: August 12, 2010Applicant: PNEUMOFLEX SYSTEMS, LLCInventors: W. Robert ADDINGTON, Stuart P. MILLER, Michael M. PHELIPA, Robert E. STEPHENS
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Patent number: 7766012Abstract: A device for the controlled inhalation of therapeutic aerosols comprises means providing individual patient parameters and/or aerosol parameters for the inhalation. The aerosol doses, such as the tidal volume and the respiratory flow, are individually adjusted on the basis of these individual parameters. Thus, the inhalation device may be individually adjusted to the patient to be treated.Type: GrantFiled: March 16, 2001Date of Patent: August 3, 2010Assignee: Activaero GmbHInventors: Gerhard Scheuch, Thomas Meyer, Knut Sommerer, Axel Greindl, Bernhard Müllinger
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Patent number: 7766018Abstract: A device which facilitates the absorption of nicotine in order to reduce the incidence of tobacco smoking is disclosed. The device includes a tube defining an interior space. The tube has a first end with an opening and a second end. An inhalable, flowable liquid or gel composition is disposed in the interior space of the tube. The composition may include water, at least one vitamin, a flavoring agent, and nicotine. The flavoring agent may include an intense sweetener such as sucralose, and a natural or artificial fruit flavor. A user inhales on the first end of the tube of the device as a substitute oral activity to tobacco smoking and thereby ingests a source of nicotine that reduces the withdrawal symptoms experienced when smoking is stopped.Type: GrantFiled: September 30, 2005Date of Patent: August 3, 2010Assignee: Smoke-Break, Inc.Inventors: Brett J. Roth, Terrill S. Clayton
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Patent number: 7726303Abstract: Controlled ejection of a fluid-based solute medicament includes determining an indication of a characteristic of the medicament in at least one ejection chamber, and ejecting the medicament from the at least one ejection chamber based on the determined indication.Type: GrantFiled: February 25, 2003Date of Patent: June 1, 2010Assignee: Hewlett-Packard Development Company, L.P.Inventors: David Tyvoll, Winthrop D. Childers
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Publication number: 20100126502Abstract: Apparatus (500) and components for coupling fluid or gas conducting elements, such as apparatus and components for connecting a nebulizer (501) with a gas flow system. In particular, the apparatus (500) and components are useful for connecting, in a gas-tight and quick release manner, a nebulizer (501) to a pressure-assisted breathing system, such as a mechanical ventilator or a continuous positive airway pressure (“CPAP”) system.Type: ApplicationFiled: August 21, 2006Publication date: May 27, 2010Applicant: AEROGEN, INC.Inventors: James B. Fink, Gavan O'Sullivan, Paul Dunne, Declan Moran, John Power, Niall Smith
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Patent number: 7721730Abstract: An ejection apparatus for ejecting droplets of liquid includes a loading portion, a reader, and a judging unit. The loading portion detachably loads therein a liquid cartridge container for containing liquid, and a liquid ejection cartridge having an ejecting portion for ejecting liquid separately, or as a combined kit. The reader reads information attached to at least one of the liquid cartridge container and the liquid ejection cartridge. The judging unit judges, based on the information read by the reader, whether each of the liquid cartridge container and the liquid ejection cartridge loaded in the loading portion is appropriate, or whether a combination of the liquid cartridge container and the liquid ejection cartridge is a predetermined combination. The ejection apparatus allows a user to relatively readily and accurately carry out ejection of appropriate liquid by an appropriate ejection unit.Type: GrantFiled: September 26, 2006Date of Patent: May 25, 2010Assignee: Canon Kabushiki KaishaInventors: Soji Hamano, Mitsuru Imai
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Publication number: 20100122697Abstract: A method and apparatus for nasal drug delivery comprises a first tube in fluid communication with a means for generating a negative pressure and a second tube in fluid communication with an aerosol. The first tube is contacted with one nostril, the said second tube is contacted with the other nostril, and a negative pressure is applied to the first tube, producing a negative pressure within a nasal cavity and causing the aerosol to be drawn into the nasal passages and to deposit on an internal nasal surface.Type: ApplicationFiled: November 13, 2009Publication date: May 20, 2010Inventors: Andrzej Przekwas, Vincent Harrand, Mark Papania
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Publication number: 20100125227Abstract: The method and system ventilates a patient's airway during the inspiratory phase and expiratory phase from a source of pressurized gas, typically from a compressor. The system and method supplies, to the patient airway during the inspiratory phase, a plurality of pulses of small volumes of gas from the gas source, and adds, in succession, pulses of small volumes of gas to provide successively greater volumes of gas successively increasing in pulsatile form the pressure of the gas in the patient's airway. This addition of successively greater volumes of gas serves to provide diffusive ventilation to the patient during the inspiratory phase, and, permits the patient to exhale during the expiratory phase.Type: ApplicationFiled: April 10, 2009Publication date: May 20, 2010Inventor: Forrest M. Bird
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Publication number: 20100051023Abstract: An inhaler is proposed for inhaling a preparation from a carrier and/or through a delivery channel. The carrier or delivery channel is preferably flexible, flat, band-shaped, strip-shaped, thread-like, blister-like and/or film-like and can be set in vibration by a stream of air. The carrier or delivery channel is preferably set in vibration by a separate element, which for its part is set in motion or vibration by the stream of air. Alternatively, or in addition, the inhaler has a pump with a telescopic pump chamber for generating a stream of air for expelling and/or dispersing a preparation.Type: ApplicationFiled: August 17, 2007Publication date: March 4, 2010Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventor: Heinrich Kladders
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Patent number: 7669595Abstract: A junction device for administering nebulizer treatments directly to a supply of oxygen supplied to a patient mask includes a supply conduit being couplable to an oxygen supply and a patient mask to allow oxygen from the oxygen supply to be supplied to the patient mask. A side conduit is coupled to and is in fluid communication with the supply conduit. An elbow conduit is rotatably coupled to the side conduit opposite the supply conduit. The elbow conduit is couplable to a nebulizer to permit treatments from the nebulizer to flow through the elbow conduit and the side conduit into the oxygen being supplied to the patient mask. A valve assembly is positioned in the elbow conduit between the side conduit and the nebulizer. The valve assembly opens and closes to control the treatments from the nebulizer to flowing into the elbow conduit.Type: GrantFiled: April 3, 2006Date of Patent: March 2, 2010Inventor: Bryon L. Mitchell
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Patent number: 7665461Abstract: A nebulizer for a fluid and a container holding the fluid which is insertable in the nebulizer are proposed. To improve safety in use it is proposed that the nebulizer comprises first coding means and the container is associated with second coding means, so that the container can only be inserted in the nebulizer or used therewith if the codes match. Preferably, the code associated with the container comprises clear identification of the fluid contained in the container.Type: GrantFiled: February 24, 2005Date of Patent: February 23, 2010Assignee: Boehringer Ingelheim International GmbHInventors: Bernd Zierenberg, Gilbert Wuttke, Michael Schyra, Guido Schmiedel, Hubert Kunze, Matthias Hausmann, Christian Golberg, Johannes Geser, Andreas Fiol
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Patent number: RE42911Abstract: An atomizer including a gas exit, an outlet adjacent the gas exit, and a deflector for deflecting gas issuing from the gas exit over the outlet for drawing a substance to be atomized out from one outlet and atomizing the substance in the gas issuing from the gas exit characterised in that the deflector is movable between a first position in the path of the gas issuing from the gas exit for atomization and a second and non-atomizing position.Type: GrantFiled: April 1, 2008Date of Patent: November 15, 2011Assignee: RIC Investments, LLCInventor: Jonathan S. Denyer