Abstract: An aerosol-generating device may include a housing defining at least one internal compartment. The housing may be waterproof. The aerosol-generating device may further include a power supply, an electric heater, and/or a haptic feedback device. Each of the power supply, electric heater, and/or haptic feedback device may be positioned within one or more of the at least one internal compartment.

Abstract: A system includes a converter configured to electrically couple to a power source and to a heating element of a vaporizer atomizer. The converter can be further configured to receive a first voltage from the power source and provide a second voltage to the heating element. The converter can be a direct-current to direct-current converter. A power monitor configured to electrically couple to the heating element, measure a current through the heating element, measure a voltage over the heating element, calculate a power and/or resistance, and output a control signal to the converter. The converter can be configured to be controlled by the control signal to vary the second voltage to maintain a target power or a target temperature over the heating element. Related apparatus, systems, techniques and articles are also described.

Abstract: An aerosol delivery device having condensing and non-condensing vaporization functionality is provided. The aerosol delivery device may comprise at least one housing, and a first element and second element contained within the at least one housing. The first and second element may be configured to activate and vaporize components of an aerosol precursor composition, and thereby form respectively a condensing vapor and non-condensing vapor. In response to a flow of air through at least a portion of the at least one housing, the condensing vapor or non-condensing vapor may be combinable with the air to form an aerosol.

Abstract: The invention relates to a mixing channel for an inhalation device, and in particular to a mixing channel with improved injection and mixing properties for injecting and mixing a liquid drug into an air flow streaming in the mixing channel, thereby producing an aerosol to be inhaled by a patient. One aspect of the invention relates to a mixing channel for an inhalation device, comprising an inlet opening, an outlet opening, and an injection zone located between the inlet opening and the outlet opening, wherein the injection zone has a longitudinal center axis, wherein the injection zone comprises (a) a built-in nebulizer, or (b) a detachable nebulizer, or (c) a member adapted to receive a detachable nebulizer, wherein the effective cross sectional area of the mixing channel in a plane perpendicular to the longitudinal center axis is smaller in the injection zone than upstream of the injection zone.

Abstract: A mist inhaler device (200) for generating a mist including a therapeutic for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

Abstract: A flow directing member for a vapor provision system is configured for engagement with an opening in a wall of a housing defining a reservoir for aerosolizable substrate material and with an opening in a wall of the housing defining an air flow passage, and has a liquid flow channel extending therethrough from a liquid inlet to a liquid outlet such that when the flow directing member is engaged with the housing, the liquid inlet is in communication with the reservoir and the liquid outlet is in communication with a volume for aerosol generation external to the reservoir so that aerosolizable substrate material can flow from the reservoir to the volume; and an aerosol flow channel extending therethrough from an aerosol inlet to an aerosol outlet such that when the flow directing member is engaged with the housing, the aerosol inlet is in communication with the volume and the aerosol outlet is in communication with the air flow passage so that aerosol can flow from the volume to the air flow passage.

Abstract: Provided is a system including a plurality of inhalers that each include a processor configured to determine a value of a usage parameter relating to use of the respective first inhaler, encrypt data based on the value, and transmit the encrypted data. At least two of the inhalers include different medicament, such as a rescue medicament and a maintenance medicament. The system includes an external device that includes a processor configured to distinguish between the encrypted data of each respective inhaler, determine respective usage information relating to each of the distinct types of medicament based on the respective encrypted data, and control a user interface (e.g., of the external device) to communicate the usage information related to each inhaler and/or each respective type of medicament.

Abstract: A device for detection of a cannabinoid in a sample includes a sensor including a substrate and a sensor medium on the substrate. The sensor medium includes at least one nanostructure, wherein at least one property of the sensor medium is dependent upon the presence of the cannabinoid on a surface of the sensor medium. The device further includes electronic circuitry including at least one measurement system in operative connection with the sensor to measure a variable relatable to the at least one property of the sensor medium dependent upon the presence of the cannabinoid.

Abstract: An adherence-monitoring and tracking device captures usage of a metered dose inhaler (MDI). The device includes an enclosure for enclosing a metered dose inhaler (MDI), and an electro-mechanical system forming a part of enclosure to sense and log the operation of the MDI. The electro-mechanical system includes at-least one transducer to capture one or more parameters pertaining to an operation of the MDI by the user. A microcontroller processes the captured parameters, and an output-unit renders data pertaining to operation of the MDI.

Abstract: Disclosed is a storage container, in which a valve coupled to an opening portion of a tube is not cut in advance, but the valve is cut when a liquid injection nozzle is inserted into the tube, such that a gap between the liquid injection nozzle and the valve may be perfectly blocked, thereby preventing a leak of a liquid. A storage container according to an embodiment of the present invention includes a tube made of an expandable or contractible elastic material, and a valve configured to be coupled to an upper end of the tube before a liquid is injected into the tube, in which the valve includes a ring-shaped support portion configured to be seated and supported at the upper end of the tube, and an elastic membrane extending from an end of the support portion and configured to close an opening portion of the tube.

Abstract: A virtual caregiver (VC) computing device may be provided. The VC computing device may include at least one processor in communication with at least one memory device, at least one sensor, and a payment processing network. The at least one processor may be configured to receive task data, generate, based on the task data, a task including a task identifier, a fulfillment condition, and a time deadline, store the generated task in a task database, receive, from the at least one sensor, sensor data, retrieve, from the payment processing network, transaction data, compare at least one of the received sensor data and the retrieved transaction data to the fulfillment condition to determine that the fulfillment condition has occurred, and record, in the task database, the task as fulfilled based on the determination that the fulfillment condition has occurred.

Abstract: Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for developing such an infection, comprising the step of administering an effective amount of a StIR composition to the individual.

Abstract: An electronic cigarette with a memory and ability to record the amount and duration of inhalation of nicotine vapor. The electronic cigarette may be integrated with a smart phone application or other software to record usage and provide feedback to the smoker. The application may include an algorithm for the development of a withdrawal schedule for the user to quit smoking or vaping.

Abstract: Methods of administering a liquid formulation of an ophthalmic agent to a topical ocular location of an eye are provided. Aspects of the methods include delivering to the topical ocular location a dose of the liquid formulation that can be wholly accommodated by the tear film of the eye. Devices and kits for practicing the methods are also provided. The methods, compositions and kits find use in a variety of applications, including therapeutic, diagnostic and cosmetic applications.

Abstract: The invention relates to a device comprising a body (10), a reservoir (100) mounted in an axially slidable manner relative to said body (10), a metering valve (200) assembled on said reservoir (100), said device comprising: —a blocking element (500), —a triggering element (600), —a triggering system controlled by inhalation (60) cooperating with said triggering element (600), and —an actuating member (800) cooperating with said blocking element (500), said device comprising an automatic valve release system which automatically returns said valve (210) of said valve (200) to its rest position after actuation of the valve regardless of the position of said actuating member (800).

Abstract: A base for an e-vaping device is configured to couple with multiple cartridges configured to generate separate, respective dispersions. The cartridges may include one or more atomizer assemblies or vaporizer assemblies. The base may include multiple connectors electrically coupled to the power supply. The connectors may be configured to couple multiple dispersion generators to a power supply of the base. The base may include control circuitry configured to independently control dispersion generation by dispersion generators coupled to the base. The control circuitry may independently control dispersion generation by the first and second cartridges based on cartridge information accessed through at least one of the first and second connectors. The control circuitry may control dispersion generation by controlling power supplied to the dispersion generators.

Abstract: A locking mechanism for an aerosol drug delivery device includes a first housing, a second housing, a screw and a fastening member. The first housing has a contact portion and a fastening space formed beside the contact portion. The second housing is rotatably connected with the first housing and is capable of rotating relative to the first housing along a rotation axis. The screw is rotatably connected with the second housing and is capable of rotating relative to the second housing along a central axis parallel to the rotation axis. The fastening member is movably connected with the screw and capable of being driven by the screw to move toward the contact portion. The fastening member includes a fastening portion capable of being displaced when contacting with the contact portion and entering into the fastening space to limit the relative rotation between the first housing and the second housing.

Abstract: An aerosol-generating system including a cartridge is provided, the cartridge including a liquid storage portion including a housing configured to hold a liquid aerosol-forming substrate, the housing having an opening; and a heater assembly including at least one heater element fixed to the housing and extending across an opening of the housing, wherein a width of the at least one heater element of the heater assembly is smaller than a width of the opening of the housing. The heater element may be spaced from a periphery of the opening, leading to more efficient heating and aerosol production.

Abstract: A mask apparatus includes a mask body having a fan module, a seal defining a breathing space, a pressure sensor sensing air pressure in the breathing space, a mask body cover coupled to the mask body, and a controller that controls a rotation speed of the fan module based on pressure values. The controller is configured to determine breathing information including a maximum pressure value and time point, and a minimum pressure value and time point, determine a breathing state of a user based on the breathing information, determine whether the breathing state is a steady state, determine a tidal volume of the user based on the breathing information, and control the rotation speed of the fan module based on the tidal volume.

Abstract: The disclosure is directed to compositions and methods of increasing oxygen saturation (SpO2) in subjects in need thereof as well as alleviating, treating or curing symptoms and conditions associated with lower SpO2 levels (below 95%). The compositions are preferably solid and comprise a nitrate anion source, an elemental metal (uncharged), and optionally an acid. The compositions are preferably administered orally.

Abstract: An arrangement for activating an aerosol dispenser having a conveying tube for conveying a liquid; a movable holding member holding the conveying tube; a rotatable base; and a container chamber between the holding member and the base, wherein the arrangement is configured to transmit a loading rotation of the base to a substantially axial loading movement of the holding member towards the base, and wherein the holding member has a locking structure exposed to the container chamber. An aerosol dispenser having the arrangement and a method for activating an aerosol dispenser are also provided.

Abstract: There is provided an electronically controlled, motor-driven, breath actuated metered dose inhaler for delivering aerosolized medicament or other matter to a user. The inhaler may comprise a base housing including a motor-driven actuator and other system components and a removable aerosol cartridge insertably receivable in the base housing. The inhaler may be paired with a smart phone or other client computing device to provide additional functionality, such as to provide instructional information and feedback regarding usage of the inhaler, to generate and display dosage tracking information, and to provide alerts and reminders to a user of the inhaler or others.

Abstract: An aerosol generating device includes a storage tank configured to store an aerosol generating material; a compressed air generator configured to generate compressed air; and a nozzle including an inlet end through which compressed air flows in and an outlet end through which the compressed air flows out, wherein the aerosol generating material stored in the storage tank is atomized into an aerosol by colliding with the compressed air discharged from the outlet end of the nozzle.

Abstract: Aspects of the instant disclosure relate to electronic cigarettes with two or more liquid reservoirs with liquid solutions for vaporization by an atomizer.

Abstract: A cartridge and a nebulizer for nebulizing a fluid as well as a method for fluidically connecting the cartridge to the nebulizer are proposed. The cartridge comprises a closure with a valve, wherein the valve displaces fluid into the nebulizer when opened. Further, the cartridge forms two axially spaced sealings with the nebulizer when connected.

Abstract: Alprazolam formulated as an inhaled condensation aerosol and method for treating epilepsy and/or seizures.

Abstract: A signal generator has a generator output. The signal generator is configured to generate first and second signals at the generator output. The first signal has a first frequency, and the second signal has a second frequency. Switching circuitry has a circuitry input and a circuitry output. The circuitry input is coupled to the generator output. The circuitry output is adapted to be coupled to an ultrasonic transducer mechanically coupled with a surface. The switching circuitry is configured to: provide the first signal to the ultrasonic transducer at the first frequency to reduce a fluid droplet on the surface from a first size to a second size; and provide the second signal to the ultrasonic transducer at the second frequency to reduce the fluid droplet from the second size to a third size.

Abstract: The present disclosure relates to systems and methods for producing a consistent and effective herbal vapor. A sealed container pod may include a chamber wall defining an internal volume within which a pre-processed herbal composition (e.g., cannabis) is located. The container pod may include filters for the vapor produced from the herbal composition. The container pod may also include a support member for holding and evenly distributing the herbal composition within the internal volume during vaporization. A vaporizer may be configured to obtain information regarding the contents of the herbal composition. The vaporizer may expose the herbal composition to an automated series of timed temperature adjustments specifically tailored for producing a desirable herbal vapor. The herbal vapor may be collected into a bag and/or canister for subsequent consumption.

Abstract: Disclosed herein are devices and methods for the use of medicament devices. The devices and methods may be used to detect or sense one or more parameters of a medicament device, for instance, shake parameters, actuation parameters, or inhalation airflow parameters. The devices and methods may be used to indicate to a user that the medicament device is in an appropriate condition for actuation of the medicament device. The devices and methods may be used to indicate to a user that the medicament device is in a condition to deliver an intended dosage range of a formulation. The devices and methods may further be used to guide a user through proper usage of a medicament device.

Abstract: The present disclosure relates to an electronic smoking article that provides for improved aerosol delivery. Particularly, the article provides for separate delivery of two or more components of an aerosol precursor composition to one or more heaters so as to control the rate of delivery or the rate of heating of the separate components of the aerosol precursor composition.

Abstract: An aerosol generating system includes a heater assembly and a manually operated pump. The pump includes a hollow member with an inlet portion and an outlet portion. The inlet portion of the hollow member is configured connectable with a liquid storage portion. The outlet portion of the hollow member is in fluid communication with a dispensing assembly. The pump is configured to dispense a liquid material onto the heater assembly. The pump is configured to pump the liquid material from the liquid storage portion via the dispensing assembly and onto the heater assembly.

Abstract: An aerosol-generating device is provided, including: a housing defining a mouthpiece end, a distal end, a sidewall between the mouthpiece end and the distal end, and a chamber within the housing, the chamber being configured to receive a liquid container, the housing including a retainer configured to retain the liquid container within the housing, the retainer including a magnetic retention mechanism; and a power source disposed within the housing, the sidewall of the housing defining an insertion window through which the liquid container is positionable inside the chamber. An aerosol-generating system and a liquid container are also provided.

Abstract: A method of oral delivery of a medication to a user's lungs with an inhaler that includes the steps of (a) receiving an actuation signal in response to release of the medication from the inhaler, (b) receiving a first accelerometer measurement indicating an orientation of the inhaler, (c) storing the actuation signal and the first accelerometer measurement in a memory, (d) determining whether the orientation of the inhaler exceeds a predetermined proper orientation threshold, and (d) determining a quality of use of the inhaler based on the actuation signal and the first accelerometer measurement.

Abstract: Systems and methods for providing respiratory therapy are disclosed. One device includes a nasal cannula comprising at least at one nasal prong, tubing and a breathing gas conduit. The nasal prong has a proximal tip and a distal end connected to the breathing gas conduit. The breathing gas conduit has an inlet port, an outlet port, and a walled flow path connecting the inlet and outlet ports, such that the conduit directs the breathing gas from the tubing to the proximal tip of the nasal prong. A nebulizer is secured to the nasal cannula and operable to aerosolize a medicament via a vibrating mesh. The vibrating mesh is secured to the nasal cannula and is positioned adjacent to the breathing gas conduit such that the aerosol is entrained with the breathing gas at proximal tip of the nasal prong.

Abstract: A wearable hand sanitizer dispenser may be worn on a wrist of a wearer and selectively actuated to discreetly dispense liquid hand sanitizer onto a palm of the wearer's hand. The wearable hand sanitizer may include a dispenser housing configured to contain a supply of liquid hand sanitizer. The dispenser housing may be configured for attachment to the wrist. At least one sanitizer dispensing nozzle may be in fluid communication with the dispenser housing interior and may extend from the dispenser housing in positional alignment with the wearer's palm. Accordingly, the liquid hand sanitizer can be selectively and discreetly dispensed from the dispenser housing through the sanitizer dispensing nozzle onto the palm of the hand. The wearer may rub the hands together to spread the dispensed liquid hand sanitizer over the hands to sanitize the hands.

Abstract: A battery-operated ultrasonic diffuser includes a rechargeable lithium-ion battery and a liquid management system that allows a user to safely move the diffuser when it is full.

Abstract: An ultrasonic electronic rhinitis therapeutic apparatus with far-infrared atomized coconut essential oil is disclosed. The apparatus includes a nasal plug part and a nasal alar part. The nasal plug part includes an insertion column disposed in a nostril. The insertion column is internally provided with a coconut powder, and a far-infrared generating tube is arranged in the coconut powder. An ultrasonic generator is arranged in the nasal alar part, and the nasal alar part is fitted on the lateral side of the nasal alar. In the disclosure, the oil and acid substance in the coconut powder are atomized by far-infrared light and are atomized under the aid of pulse ultrasonic wave in the nasal cavity to be inhaled into the internal tissues of the nasal cavity, sinus and the like.

Abstract: Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.

Abstract: A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.

Abstract: A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.

Abstract: A nebulizer device and a nozzle module are provided. The nebulizer device includes a nebulizer module, the nozzle module, and a control module. The nozzle module includes a main body unit and a guide unit. The main body unit can be detachably connected to the nebulizer module. The main body unit has a plurality of openings penetratingly formed therethrough, an accommodating space, and an output part, and the openings and the output part are in spatial communication with the accommodating space. The main body unit corresponds to an inner wall of the accommodating space and protrudes toward the accommodating space to form a plurality of guiding parts, and each of the guiding parts is adjacent to one of the openings. The guide unit is disposed in the accommodating space and has a recessed part. The control module can be detachably connected to the main body unit.

Abstract: A medical system is disclosed. The medical system can include a patient monitoring device, a patient information system, and a mobile application. The patient monitoring device can be coupled to a patient to monitor one or more physiological parameters. The patient information system can allow the patient to communicate with a clinician. The patient information system can also provide information regarding schedules, medications, and procedures to the patient. The mobile application can be communicatively coupled with the patient monitoring device and the patient information system. The mobile application can allow a clinician to receive, view, and send information to or from the patient monitoring device and the patient information system.

Abstract: An aerosol-generating system includes a liquid-storage portion including a housing configured to store a liquid aerosol-forming substrate. The aerosol-generating system also includes a heater configured to heat liquid aerosol-forming substrate, a vibratable element including a plurality of passages through which the heated liquid aerosol-forming substrate passes to form an aerosol, and an actuator arranged to vibrate the vibratable element to generate the aerosol.

Abstract: An atomizing generator, a clothing treatment device, and a control method therefor to solve the problems of the structural complexity and poor liquid level measurement accuracy of existing atomizing generators. The atomizing generator includes an outer shell and an atomizing module, an atomization cavity capable of accommodating liquid being disposed in the outer shell, and a liquid inlet, an air inlet, and a mist outlet in communication with the atomization cavity being arranged on the outer shell, the atomizing module including an ultrasonic atomizing sheet, and the atomizing module being arranged to be capable of atomizing the liquid in the atomization cavity by vibration of the ultrasonic atomizing sheet and detecting the height of the liquid level in the atomization cavity by the vibration, which simplifies the structure of the atomizing generator and increases the precision and accuracy of liquid level measurement.

Abstract: An inhaler has a housing having a patient port and a cover rotatable about a cover axis between a closed position in which the cover covers the patient port, and an open position in which the patient port is accessible, a spring surrounding a medicament container in which the cover axis intersects the container, and in which the cover is configured to drive the resilient structure to store energy therein upon rotation from the closed position towards the open position.

Abstract: The present disclosure provides a measuring device for biological tissue by using an optical sensor, the device being compact enough to fit in a user's hand and casually usable by the user. The measuring device is provided with: an optical sensor that measures optical data about an object of measurement through a measurement surface in contact with the object of measurement by irradiating the object of measurement with light from a light emitter and causing a light receiver to receive reflected light that is reflected from the object of measurement, the object of measurement being a portion of biological tissue; a temperature sensor that measures the temperature of the optical sensor; and a data processor that processes the optical data on the basis of the temperature of the optical sensor and derives a measurement result pertaining to the object of measurement on the basis of the processed optical data.

Abstract: According to some embodiments, an aerosol generating device includes: a main body including an accommodation space into which a cartridge, that is detachable, is configured to be inserted; a battery provided in the main body and configured to supply power to power consumption components included in the main body; a feedback line configured to feedback electrical connection between a heater in the cartridge and the main body based on the cartridge being inserted into the accommodation space; and a controller configured to change a mode of the aerosol generating device to a use mode based on a feedback signal being received through the feedback line when the aerosol generating device is set to a shipping mode.

Abstract: In order to detect the occurrence of malfunctions in a sensor, a power supply unit is provided with a suction action sensor which detects an aerosol generation request, and a control portion which, on the basis of an output value from the sensor which has detected an aerosol generation request, detects whether the sensor is in a normal state or an abnormal state. In one case, a control unit of the device may determine that the sensor is an abnormal state when the number of aerosol generation requests within a predetermined time period is greater than a predetermined threshold.

Abstract: The claimed subject matter provides a control component that regulates output of an electronic vaporizer used to simulate smoking. The control component manages power to a heating element. A power detect component collects a parameter of the heating element to determine actual power output thereof. The control component dynamically adjusts the power source based on the actual power output.

Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.