Abstract: The invention relates to an aerosol-generating device. The device may comprise a main body (10) that may comprise a connection portion (16). The device may further comprise a removable mouthpiece (12) that may comprise a first connection element (14). The first connection element may be configured removably engageable with the connection portion of the main body. The first connection element may be configured to irreversibly change upon disengagement of the first connection element from the connection portion of the main body.

Abstract: A device for monitoring drug use from a drug dispenser in the form of a dispenser cap, especially an inhaler, comprising a sensor for measuring drug release from the dispenser. As a drug release measurement sensor (2) a piezoelectric transducer (2) is used, while a piezoelectric transducer (2) is connected to a microprocessor. The cap includes the activator (1) of the drug release measurement sensor (2) associated movably connected with the piezoelectric transducer (2), wherein the piezoelectric transducer (2) is located in the cap in such a way that, with the help of the activator (1) of the drug release measurement sensor (2), after using the drug dispenser, the force pressure on the cap as a kinetic force is transmitted from the activator (1) of the drug release measurement sensor (2) directly to the piezoelectric transducer (2), which measures the transferred kinetic force.

Abstract: An apparatus and method for providing a nebula or aerosol to a patient is described. In one aspect, the nebulizer is composed of a minimum number of parts to reduce complexity for automated or human assembly. The nebulizer may include an inhalation valve, exhalation valve and biasing member integrated into a single diaphragm structure that may be connected with an actuator and inserted into a housing for controlling nebulization of a medicine to a patient in response to the patient's breathing or in a continuous nebulization mode.

Abstract: A hand-held device for metered dispensing of sprayable substances, in particular inhaler medicaments, includes a housing and a cartridge which can be displaced into a dispensing position by a pressure application relative to the housing, wherein the housing has a mouthpiece, wherein the cartridge can be displaced initially into a ready-to-dispense position and a dispensing spray process can be triggered by sucking in, wherein the displacement of the cartridge can be executed by tensioning a spring supported on the housing and acting on the cartridge. The spring is displaced into the position to perform a spraying process, but is hindered by a counterforce that can be deactivated by application of a negative pressure through the mouthpiece of the hand-held device A valve flap is moved by the negative pressure and cancels a mechanical block of the movement of the cartridge.

Abstract: An add-on device for a metered dose inhaler, an observance improvement system, and a method for improving observance of use in metered dose inhalers, the add-on device comprising an observance system housing component comprising an observance system with at least one pressure sensor; a mouthpiece component configured to fit, surround and removably engage with an exterior surface of a mouthpiece outlet provided on the metered dose inhaler; wherein the observance system housing is configured to fit and removably engage with the mouthpiece component; and the mouthpiece component is specifically adapted to conform to the exterior surface of the mouthpiece outlet of the metered dose inhaler without obstructing delivery of a dose of drug through the outlet.

Abstract: The present invention relates to a metered dose inhaler (MDI) device comprising a mechanically activated visual cue representing a number of doses expelled from, or doses remaining in, a drug-containing cartridge or canister locatable within a body of said MDI, wherein the visual cue is visible through at least a portion of the body of said MDI, and a removable data processing system configured to verify the dose of drug administered and/or inhaled, wherein the MDI device further comprises a correlation system configured to correlate physically released doses from the drug containing cartridge or canister with the administration and/or inhalation data stored in the removable data processing system.

Abstract: The present invention describes articles, such as smoking articles, that can provide an inhalable substance in a form suitable for inhalation by a consumer. The article comprises a cartridge with an inhalable substance medium therein, control housing that includes an electrical energy source and an electrical power source, and a heating member that may be located in either the cartridge or the control housing. The control housing further may include puff-actuated current actuation components and current regulation components.

Abstract: The invention relates to a spray device having a spray nozzle unit and at least one further spray nozzle unit. Each spray nozzle unit has at least one spray nozzle body, wherein at least one spray nozzle body comprises a chamber for receiving a pressurized fluid. The chamber is bound by a spray wall having at least one spray orifice that extends through the spray wall and opens to an external environment. Each of at least one orifice in a spray wall has a substantially identical predetermined size lying in a predetermined range and releases a mono disperse spray jet of the pressurized fluid fed from the associated reservoir. The range within the first spray nozzle unit differs from the range within at least one further spray nozzle unit; particularly, the ranges do not overlap.

Abstract: An inhalation-synchronized fluid dispenser device having a body; a mouthpiece; a reservoir; a valve; a blocking element; a trigger element; and an inhalation-controlled trigger system including an inhalation-sensitive member deformable or movable so that when the inhalation-sensitive member is deformed and/or moved, it moves and/or deforms the trigger element towards its release position, thereby making it possible to move and/or deform the blocking element towards its actuation position. The device has a ring that co-operates with the blocking element, such that in the blocking position, an axial projection of the ring co-operates with an axial blocking extension so as to block the reservoir, and in the actuation position, the axial projection co-operates with an axial recess, thereby enabling the reservoir to move axially.

Abstract: An inhalation-synchronized fluid dispenser device having a body (10) with a mouthpiece (400), a reservoir (100), a valve (200) assembled by a fastener element (5) on the reservoir (100). The device includes a blocking element (500) that pivots about a pivot axis B between a blocking position and an actuation position; a trigger element (600) that pivots about a pivot axis C; and an inhalation-controlled trigger system. The device includes an actuator member (800) mounted to move axially between a rest position and a primed position. A spring (850) is arranged so that when the actuator member (800) moves towards its primed position, the spring (850) is compressed, so as to transmit an axial force (F) to the reservoir (100).

Abstract: Apparatus for providing a mixture including nitrous oxide (N2O) to a subject are disclosed. One apparatus includes at least one reservoir storing at least N2O and a delivery mechanism in communication with each reservoir. The delivery mechanism is configured to introduce a mixture including N2O and at least a first additive combined with the N2O to one of a mouth of a subject, a nose of the subject, or both the mouth and the nose of the subject for inhalation by the subject.

Abstract: An aerosol generation device includes: a load configured to heat an aerosol generation article by using power that is supplied from a power source, the aerosol generation article comprising an aerosol-forming substrate configured to hold or carry at least one of an aerosol source and a flavor source; and a control unit configured to control the power that is supplied from the power source to the load. When starting the supply of power to the load in a non-operation state, or when the load is in a preparation state in which the load is not capable of generating a predetermined amount or more of aerosols from the aerosol generation article, the control unit is configured to control the power that is supplied from the power source to the load by feed-forward control.

Abstract: The present invention relates to a method for manufacturing a wind turbine blade shell part made of a fibre-reinforced composite structure, including steps of mounting a plurality of fastening devices on a mounting plate to form a root end assembly, the mounting plate comprising one or more first openings for evacuating air; arranging the root end assembly over a mould surface of a mould; arranging an air-tight cover member so as to form a mould cavity; evacuating air from the mould cavity via at least the one or more first openings of the mounting plate; and supplying a polymer into the mould cavity and allowing the polymer to cure so as to form the composite structure. A root end assembly for use in the method is also provided.

Abstract: An inhaler for delivery of a medicament by inhalation includes an inhaler body for receiving a canister having a dispensing valve. A drive mechanism is provided for driving the canister from a rest position in which the valve is closed to an actuating position in which the valve is open. A resetting mechanism is provided for resetting the drive mechanism. A return mechanism is provided for returning the canister from the actuating position to the rest position, wherein the return mechanism comprises a damping system that is configured to enable the canister to automatically return from the actuating position to the rest position within a predetermined time period. A method of operation of an inhaler is also disclosed.

Abstract: A breath actuated metered dose inhaler may comprise a canister fire system configured to fire a medicament containing canister in response to patient inhalation. The canister fire system may comprise a pneumatic force holding unit and having a rest configuration in which a metering valve of the canister is in a refill configuration; a prepared configuration in which a canister actuation force is retained by the pneumatic force holding unit and the canister fire system is actuatable by patient inhalation induced airflow; and a fire configuration in which the metering valve is in a dose delivery position. When in the prepared configuration, the force retained by the pneumatic force holding unit may be reduced by less than about 6% over a period of 5 minutes, preferably less than about 3% over a period of 5 minutes.

Abstract: An acoustic dose meter is provided comprising a housing, and a cylindrical seat for staging a pressurized medicine canister. The housing includes at least one compartment for housing electronics and passageways for connecting electronics for power and data communication. A microprocessor including a transient memory containing machine instruction is also included. Additionally, a power source connected to the microprocessor, a power switch connected to the microprocessor and the power source for booting the microprocessor are added. At least one visual display device connected to the microprocessor for displaying available doses is provided. A first set of acoustic sensors connected to the microprocessor and adapted as acoustic sound generators and a second set of acoustic sensors connected to the microprocessor and adapted as acoustic soundwave recorders are implemented to detect and analyze frequencies enabling determining of dosing count availability.

Abstract: An aerosol delivery device is provided that includes a reservoir configured to retain aerosol precursor composition, a valve configured to control a flow of aerosol precursor composition from the reservoir to a heating element controllable to activate and vaporize components of the aerosol precursor composition, a sensor configured to measure reflectance or temperature at the heating element and generate a signal corresponding to the reflectance or temperature so measured, and a control component. The control component controls operation of the valve including receiving the signal and based thereon determining a volume of aerosol precursor composition at the heating element, and causing the valve to decrease or increase a rate of the flow of aerosol precursor composition in response to the volume being respectively above or below a predetermined threshold volume.

Abstract: Described herein are dry immunogenic compositions and methods of freezing aluminum-containing vaccines such that when converted into a dried powder, the dry composition can be readily administered without loss of activity. Also described are methods of intranasal administering dry immunogenic compositions comprising antigens and aluminum adjuvants.

Abstract: A method for conditioning a hard gelatin capsule (50) having any moisture content to a dry and non-brittle state when packed for at least one week in a cavity (45) of a blister base (40) closed by a lid film (35) comprising an aluminium foil, wherein the hard gelatin capsule (50) is a hard starch capsule manufactured from collagen and the hard gelatin capsule (50) contains pharmaceuticals and wherein the dry state of the hard gelatin capsule (50) means a relative humidity of less than 50% at room temperature and the non-brittle state means that the hard gelatin capsule (50) does not break when pressed out of the cavity (45) of the blister base (40) through the lid film (35). The lid film (35) and/or the blister base (40) comprise/s a moisture-regulating buffer layer (20) with a predefined humidity. The moisture-regulating buffer layer (20) consists of a polymer or polymer mixture containing 1 to 60 wt.

Abstract: An electronic device for generating an aerosol used for administration to human respiratory tract as the aerosol, nicotine in particular, including a power unit and an evaporator unit, wherein the evaporator unit includes a heating system with a heating element and a fluid transporting element, wherein the heating element comprises a dielectric substrate with at least one resistive layer area applied thereon.

Abstract: An inhaler 10 for delivery of a medicament by inhalation. The inhaler 10 has a drive mechanism, a canister drive 22 for receiving a canister 50 of medicament, a spring 20, and a trigger mechanism with a latch 35. The latch 35 has a locked position to prevent linear movement of the canister drive 22 and holds the spring 20 in a loaded configuration; and an unlocked position in which the latch 35 is disengaged from the canister drive 22. The trigger mechanism comprises a blocker 32. The blocker 32 has a blocking position in which it contacts the latch 35 to block movement from the locked position to the unlocked position; and a rotated position in which the blocker 32 is disengaged from the latch 35 to allow it to lock and unlock.

Abstract: A component of an electronic vapor provision device with a reservoir for storing source liquid, an atomizer for vaporizing source liquid from the reservoir and delivering vapor into an air flow path through the device, and an electrical power supply for providing electrical power to the atomizer comprises an absorbent element to collect source liquid escaped from the reservoir and located so as to be upstream of the atomizer with respect to an air flow direction along the air flow path when the component is assembled into the electronic vapor provision device.

Abstract: A component of an electronic vapor provision device with a reservoir for storing source liquid, an atomizer for vaporizing source liquid from the reservoir and delivering vapor into an air flow path through the device, and an electrical power supply for providing electrical power to the atomizer comprises an absorbent element to collect source liquid escaped from the reservoir and located so as to be upstream of the atomizer with respect to an air flow direction along the air flow path when the component is assembled into the electronic vapor provision device.

Abstract: Embodiments relate to a single-use device for delivery of medication into a nasal cavity. In an embodiment, the device includes a propellant canister containing a propellant capable of propelling the compound to the nasal cavity. The propellant canister is displaceable between an unactuated position and an actuated position within the device. The device further includes an actuation element with an actuation lever configured to displace the propellant canister from the unactuated position to the actuated position. The device also includes a puncture element positioned to puncture the propellant canister, which causes the release of the propellant from the propellant canister. The device further includes a dose holding chamber containing a unit dose of the compound. The dose holding chamber is positioned such that propellant flows into the dose holding chamber and causes the compound to be propelled from the dose holding chamber to the nasal cavity of the user.

Abstract: An inhaler housing (14) for an inhaler (10) for inhaling inhalable substances, the inhaler having: a body (14) and a dose counter (24) with a return spring (28), wherein a distinct guide surface (162) is provided for guiding the end of the return spring into a recess (152), the distinct guide surface being wider than an entrance mouth (160) of the recess, a dose counter chamber (22) being provided which is separated from a tubular interior space (182) of the inhaler by a barrier (180), the barrier including a stepped upper wall area (184) including at least three steps (186, 188, 190, 192) at different levels, the inhaler having a valve stem block (62) having an inner bore and a valve stem block having a seal (224) in the inner bore with a second diameter which is smaller than a first diameter of the inner bore, the inhaler having a canister (150) being adapted to move during operation between 1 and 4 mm, a drive being arranged to apply a firing force of between 15N and 60N of force to the canister at a posit

Abstract: Systems, apparatus, and methods are described for delivering a therapeutic substance to a target area within or proximate to a nasal cavity of a subject, including a reservoir configured to contain the therapeutic substance and a delivery interface by which the therapeutic substance is delivered to the target area. In some embodiments, systems, apparatus, and methods described herein can deliver a therapeutic substance using iontophoresis and/or electroosmosis.

Abstract: A cartridge for an aerosol-generating system is provided, including a liquid storage portion including a housing containing a liquid aerosol-forming substrate, the housing having an open end; and a heater assembly including: an electrical heating element configured to heat the substrate to form an aerosol, the heating element including a planar filament arrangement having one or more electrically conductive filaments, an electrically insulating substrate having a planar attachment face, the filament arrangement disposed on the planar attachment face, and connectors arranged at opposite ends of the heating element and forming two separate electrical contacts configured to apply power to the filament arrangement, at least a portion of the heater assembly is fluid-permeable, and the heater assembly is arranged over the open end of the housing.

Abstract: This invention reveals the potential applications of modified porcine plasma fibronectin that could be applied as a safe material for clinical wound healing and tissue repair. In order to seek safe sources of plasma fibronectin for practical consideration in wound dressing, this invention isolated and modified fibronectin from porcine plasma and demonstrated that modified porcine plasma fibronectin has similar ability as homo plasma fibronectin being as a suitable substrate for stimulation of cell adhesion and directed cell migration. The present invention also reveals a material and a pharmaceutical composition enhance wound healing.

Abstract: An inhaler (60) has a breath actuated trigger mechanism (100) reactive to an inhalation flow to trigger the release of a substance to be inhaled. The inhaler (60) has an inspiration flow which is subject to a higher degree of flow governing post-triggering than pre-triggering. This allows the triggering flow rate to be closer to, or even higher than, the governing flow rate of the inhaler.

Abstract: Some embodiments are directed to an adherence monitor for use with a tethered cap inhaler device. The adherence monitor engages the inhaler device, and includes a tether opening located within a housing of the adherence monitor for receiving the tether. The tether opening is in the form of a slot in a base portion of the housing. The path length of the tether around the adherence monitor is kept from being increased, compared to its path length when the adherence monitor is not attached to the inhaler, by having the slot located to allow the tether to pass through the slot. Various sensors of the adherence monitor in various embodiments detect inhaler usage.

Abstract: Apparatus and methods are described for use with a vaporizer that vaporizes at least one active ingredient of a plant material. In response to receiving a first input to the vaporizer, the plant material is heated, in a first heating step. An indication of the temperature of the plant material is detected, and, in response to detecting an indication that the temperature of the plant material is at a first temperature, the first heating step is terminated, by withholding causing further temperature increase of the plant material. The first temperature is less than 95 percent of the vaporization temperature of the active ingredient. Subsequently, a second input is received at the vaporizer. In response thereto, the plant material is heated to the vaporization temperature, in a second heating step. Other applications are also described.

Abstract: This invention relates to a compliance monitor for monitoring patient usage of a medicament delivery device, where the medicament delivery device includes a store of medicament and a medicament dispensing means. The compliance monitor includes a housing adapted to enclose the medicament delivery device, and a dose counter, associated with the housing, for recording the delivery of a dose of medicament to the patient from the medicament delivery device. The arrangement and construction is such that the housing is loosely coupled to the medicament delivery device, whereby the housing is able to move relative to the medicament delivery device during the delivery of the dose of medicament, and it is this movement which actuates the dose counter, either directly or indirectly, in order to record the delivery of the dose of medicament.

Abstract: An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.

Abstract: An aerosol-generating component for an aerosol-generating article is provided, the aerosol-generating component including: a combustible heat source; an aerosol-forming substrate; and a heat-transfer element disposed between the combustible heat source and the aerosol-forming substrate, the heat-transfer element including a cup-shaped receptacle defining a cavity, and the aerosol-forming substrate forms a coating on at least a portion of an inner surface of the cup-shaped receptacle. An aerosol-generating article including the aerosol-generating component, and a method of manufacturing the aerosol-generating component are also provided.

Abstract: A respiratory flow therapy apparatus including a sensing chamber which measures a flow of gases provided to a patient. The sensing chamber can be located after a blower and/or mixer. The sensing chamber can include an ultrasonic transducer, a temperature sensor, a heated temperature sensing element, and/or a gas concentration sensor. A flow path of gases used in conjunction with the sensor system prevents unwanted vorticity in the flow of gases that can create anomalies in measuring flow.

Abstract: An electronic module for an inhaler includes a printed circuit board and electronic components configured to detect at least a status and/or at least a working parameter of the inhaler when the electronic module is attached to the inhaler. A battery is permanently joined to the printed circuit board. A first terminal and a second terminal are electrically connectable one to the other through a main switch to close a circuit between the battery and the electronic components. In a rest configuration, the first and second terminals are electrically separated by the main switch. In a work configuration, the first terminal and the second terminal are electrically connected one to the other through the main switch.

Abstract: The present invention relates to an add-on device for a metered dose inhaler, an observance improvement system, and a method for improving observance of use in metered dose inhalers, the add-on device comprising an observance system housing component comprising an observance system with at least one pressure sensor; a mouthpiece component configured to fit, surround and removably engage with an exterior surface of a mouthpiece outlet provided on the metered dose inhaler; wherein said observance system housing is configured to fit and removably engage with said mouthpiece component; and said mouthpiece component is specifically adapted to conform to the exterior surface of the mouthpiece outlet of the metered dose inhaler without obstructing delivery of a dose of drug through said outlet.

Abstract: Methods and systems for monitoring the status and usage of a metered dose inhaler (MDI) and communicating status, usage, and guidance information to a user of the MDI and to a mobile computing device are presented herein. An IMD includes a dosage dispense detection device, an accelerometer, and a visual transducer, an audio transducer, a haptic transducer, or any combination thereof. The dosage dispense detection device detects when a user applies a compressive force across the IMD. The accelerometer measures a shaking of the IMD by a user before self-administering a dose. The IMD determines whether the medicine is adequately shaken by the user, and if so, communicates an indication to the user that the pressurized canister of medicine is ready for dosage. In another aspect, the IMD communicates a sequence of indications that mark each transition of a dosage regimen plan to self-administer a dosage of medicine.

Abstract: An aerosol inhalation spacer for use with a metered-dose inhaler canister is disclosed. The spacer includes a transparent chamber housing having a body with an input end and an output end and defining an interior space. A mouthpiece is connected to the output end of the chamber housing. An inhaler adapter is connected to the input end of the chamber housing. A valve member is disposed between the mouthpiece and the output end of the chamber housing, the valve member includes a one-way inhalation valve and a one-way exhalation valve. A flow indicator is connected to the inhaler adapter and extends into the interior space of the chamber housing for indicating an inhalation flow rate to the user.

Abstract: An electronic smoking device includes a liquid supply (34) and an atomizer in a housing. The liquid supply (34) includes at least two container members (34a, 34b) attachable to one another through a connection mechanism to form a liquid supply main body. Each of the container members (34a, 34b) may have an outlet (341a, 341b) sealed by a sealing member (342a, 342b) and a second end which is closed, and an aerosol channel (343a, 343b) formed between the container members.

Abstract: An inhalation-synchronized fluid dispenser device having a body (10; 10?) provided with a mouthpiece (400), a fluid reservoir (100) containing a fluid and a propellant gas being mounted to slide axially in the body (10; 10?), a metering valve (200) including a valve member (210) assembled on the reservoir (100) for selectively dispensing the fluid. The device includes an actuator element (500, 500?, 500?; 550) movable and/or deformable between a non-actuation position and an actuation position; an inhalation-controlled trigger system including an inhalation-sensitive member (60, 61; 65, 66) deformable and/or movable under the effect of inhaling and when deformed and/or moved, moving and/or deforming the actuator element (500, 500?, 500?; 550) from its non-actuation position towards its actuation position; an electronic dose counter (1000); and a signal-transmitter (1100) for communicating, in particular communicating remotely, information relating to the actuations of the device.

Abstract: An optimization methodology is employed to match vibratory inhaler devices having certain characteristics to the particular anatomical and acoustic properties of a patient's vocal tract, in order to achieve the most effective dispersion of a dry powder medicament using inspiratory effort of a user of the inhaler. In embodiments, optimization involves employing one or more measurements of acoustic frequency spectrum properties as well as one or more anatomical/geometric measurements of the structures comprising the particular patient's mouth, pharynx, and upper respiratory tract and matching a vibratory inhalation device that corresponds thereto.

Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port.

Abstract: A breath-responsive metered dose inhaler having a trigger mechanism for triggering delivery of a medicament and a trigger mechanism chassis for locating the trigger mechanism within the inhaler, the trigger mechanism including a breath responsive member moveable upon inhalation of the user from a primed position in which the inhaler is prevented from delivering medicament, to a triggered position in which the medicament is delivered to the user, a spring which is flexible along its longitudinal axis, wherein the spring is configured to bias the breath responsive member from its triggered position to its primed position by flexure along its longitudinal axis.

Abstract: This present disclosure describes a computer-implemented method for updating a plurality of parameters on a medical inhaler sensor via a wireless connection by a client device. The client device stores the plurality of parameters for the medical inhaler sensor on the client device. The client device updates one or more parameters of the plurality of parameters on the client device. The client device receives a plurality of periodic chirps from the medical inhaler sensor, and can establish the wireless connection with the medical inhaler sensor in in response to having received a chirp. Through the wireless connection, the client device transmits the updated one or more parameters of the plurality of parameters to the medical inhaler sensor.

Abstract: A method and apparatus is provided for spraying a solution, such as a cleaning solution a barrier material, out of a spray canister device to a surface area of a human body. The spray canister device generally includes a removable sleeved cover element covering an inner canister element. The spray canister device with the removable sleeved cover is easy to carry and easy to spray, and can be handled manually or functions together with other devices.

Abstract: The connector is configured to couple a first section and a second section of an e-vaping device, and the connector includes a flange with a first end and a second end, a shaft extending from the first end of the flange, an outer shelf being formed by a portion of the first end of the flange, a cylindrical base extending from the second end of the flange, and an inner shelf within the connector, the cylindrical base and the inner shelf at least partially defining a longitudinal opening, the flange defining at least one first notch, the at least one first notch at least partially along the second end of the flange.

Abstract: In certain embodiments, a ventilator may provide interactive guidance for obtaining a subject's expiratory flow limitation results. In some embodiments, the ventilator may cause a progressive color component to be presented, where the progressive color component indicates a progression from one color proximate one side of the progressive color component to another color proximate another side of the progressive color component. The ventilator may cause a forced oscillation to be continuously applied to an airway of the subject for a time period. The ventilator may monitor the subject's degree of expiratory flow limitation based on output signals generated by one or more sensors as the forced oscillation is continuously applied for the time period. The ventilator may cause, based on the monitoring, a movable component's position on the progressive color component to be continuously updated during the time period to indicate the degree of expiratory flow limitation.

Abstract: A respiratory system and method comprise a tracker module adaptable to be secured to a variety of inhalers, the tracker module sensing activation of the medication canister of the inhaler for delivery of medication to a user. The tracker module also senses the rate of inhalation air flow of the user when inhaling medication for determination of proper inhaler use. Upstream and downstream sensors provide flow information to determine quality of the inhalation. A flow sensor is an integral part of the tracking module and can be used on multiple inhalers. Other sensors are provided that monitor user presence at the inhaler, user technique in using the inhaler, and the attitude of the inhaler when it was used. Low power devices are used to conserve battery power. A spirometer provides user lung function data.

Abstract: In one aspect of the present disclosure, an apparatus for delivering a powdered agent into a subject's body may include a powder chamber housing the powdered agent. The apparatus also may include a chassis in fluid connection with the powder chamber. The chassis may include a first passage for receiving a pressurized gas, a second passage for receiving the powdered agent from the powder chamber, and a junction in fluid communication with the first passage and the second passage. At least a first portion of the pressurized gas is introduced into the powdered agent at the junction to fluidize the powdered agent.