Means To Regulate Or Vary Operation Of Device Patents (Class 137/825)
  • Patent number: 9050596
    Abstract: The present invention relates to microfluidic systems and methods for controlling the flow of fluid using passive components engineered into the microchannels. These passive flow components include fluidic diodes, fluidic capacitors, and fluidic inductors. Various fluidic circuits are provided to control fluid flow including fluid rectifiers, fluid band pass filters, and fluid timers.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: June 9, 2015
    Assignee: University of Virginia Patent Foundation
    Inventors: Christopher J. Easley, James M. Karlinsey, James P. Landers, Dan Leslie, Matthew R. Begley
  • Patent number: 8944083
    Abstract: A microfluidic device for generation of monodisperse droplets and initiating a chemical reaction is provided. The microfluidic device includes a first input microchannel having a first dimension and including a first phase located therein. The device also includes a second input microchannel having a second dimension and including a second phase located therein. In accordance with the present disclosure, the second dimension is different from the first dimension and the first phase is immiscible in the second phase. A microchannel junction is also present and is in communication with the first input microchannel and the second input microchannel. The device further includes an output channel in communication with the microchannel junction and set to receive a monodisperse droplet. In the present disclosure, the difference in the first dimension and the second dimension creates an interfacial tension induced force at the microchannel junction which forms the monodisperse droplet.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: February 3, 2015
    Assignee: UT-Battelle, LLC
    Inventors: Charles Patrick Collier, Scott T. Retterer, Seung-Yong Jung
  • Publication number: 20150029478
    Abstract: A fuel stream generator comprising a nozzle connected to a fuel reservoir, wherein the nozzle is provided with a gas inlet configured to provide a sheath of gas around fuel flowing along the nozzle is disclosed. Also disclosed are a method of generating fuel droplets and a lithography apparatus incorporating the fuel stream generator.
    Type: Application
    Filed: January 22, 2013
    Publication date: January 29, 2015
    Applicant: ASML Netherlands B.V.
    Inventors: Hendrikus Gijsbertus Schimmel, Dzmitry Labetski
  • Patent number: 8844571
    Abstract: A fluid actuator for influencing the flow along a flow surface by ejecting a fluid flowing through the fluid actuator is described. The fluid actuator has at least two outlet lines with outlet openings at the respective ends thereof, and a feed line connected to the outlet lines for feeding fluid at a supply pressure, a flow direction diverting device into which the feed line opens and out of which the outlet lines open, and an adjusting device coupled to the flow direction diverting device to control the latter. The adjusting device is configured so the fluid is conducted successively in a cyclic sequence into each of the outlet lines. A discharge device for discharging a fluid out of a flow body, and a flow body having a multiplicity of discharge openings and a discharge device of said type are also described.
    Type: Grant
    Filed: January 22, 2012
    Date of Patent: September 30, 2014
    Assignee: Airbus Operations GmbH
    Inventors: Burkhard Gölling, Matthias Bauer
  • Patent number: 8844570
    Abstract: Methods and devices for using one or more fluidic channels for generating binary states are described. In particular, the present teachings relate to incorporating such fluidic channels into devices that use the generated binary states in various applications.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: September 30, 2014
    Assignee: California Institute of Technology
    Inventor: Casey G. Glick
  • Publication number: 20140238521
    Abstract: An ionic field effect transistor includes: a substrate; a polymer layer that is formed on the substrate and in which a first flow path and a second flow path that is separately disposed from the first flow path are formed; and a gate electrode that is formed between the substrate and the polymer layer and that contacts the first flow path and the second flow path, wherein a heterogeneous triangular nanochannel that connects the first flow path and the second flow path is formed between the gate electrode and the polymer layer.
    Type: Application
    Filed: February 17, 2014
    Publication date: August 28, 2014
    Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Geunbae LIM, Sung-Jae Kim, Bumjoo Kim, Joonseong Heo, Hyukjin J. Kwon
  • Publication number: 20130291981
    Abstract: The invention relates to a fluid actuator for influencing the flow along a flow surface by ejection of a fluid. By means of a like fluid actuator a continuous flow is distributed to at least two outlet openings in order to generate fluid pulses out of these outlet openings. Control of this distribution takes place inside an interaction chamber supplied with fluid flow via a feed line. Into this interaction chamber there merge at least two control lines via control openings to which respective different pressures may be applied. The flow in the interaction chamber is distributed to the individual outlet openings as a function of the pressure difference at the control openings.
    Type: Application
    Filed: March 27, 2013
    Publication date: November 7, 2013
    Inventor: Airbus Operations GmbH
  • Patent number: 8551599
    Abstract: A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: October 8, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: Zhishan Hua, Erdogan Gulari, Mark A. Burns, Rohit Pal, Onnop Srivannavit
  • Patent number: 8534319
    Abstract: Methods and devices using a co-radial arrangement of serial siphon structures composed of siphon valves each separated by a capillary valve to save radial space in a fluidic system. Such serial siphon valves allow to sequentially distribute liquids in a fluidic system upon application of successive centripetal accelerations and decelerations applied to a rotary platform.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: September 17, 2013
    Assignees: Universite Laval, The Regents of the University of California
    Inventors: Michel G. Bergeron, Regis Peytavi, Horacio Kido, Marc Madou
  • Patent number: 8524154
    Abstract: A metabolite monitoring system comprising a microdialysis probe including a semi-permeable membrane and a probe flow path passing from an inlet through a sensing volume adjacent to said semi-permeable membrane to an outlet, a fluid delivery device for delivering dialysate to said inlet; and a metabolite monitoring system associated with said outlet for monitoring a concentration of at least one metabolite in said dialysate from said microdialysis probe, wherein said fluid delivery device is configured to deliver a pulsed flow of said dialysate to said inlet.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: September 3, 2013
    Assignee: G-Sense Ltd.
    Inventors: Avraham Shekalim, Noam Peleg
  • Patent number: 8500964
    Abstract: A manufacturing method of a bubble-type micro-pump is provided. At least a bubble-generating unit is provided on the bubble-generating section. Because of the varied surface energies on the top of the bubble-generating section, the varied backfilling velocities of the fluid of the front end and the rear end cause fluid moving when a bubble vanishes. The top surface of the bubble-generating section is subjected to a particular surface treatment to form a surface energy gradient. Examples of surface treatment include sputtering a thin film with varied densities or thickness, radiating one or multi-layer thin films by a laser beam, etc.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: August 6, 2013
    Assignee: Benq Materials Corp.
    Inventor: Chen Peng
  • Patent number: 8475712
    Abstract: An arrangement for the exposure of a pumpable medium to an electric field. The arrangement comprises, at least two power supplies (100) for the generation of electrical voltage, at least one non-conducting chamber (102) for pumping said pumpable medium, which said at least one chamber (102) is provided with a first (106) and a second electrode plate (108), a control means (104) for controlling said at least two power supplies (100). During control the control means (104), by synchronous control, establishes a series connection between at least two of said at least two power supplies (100), the first electrode plate (106) and the second electrode plate (108). A resulting composite voltage arises between the first (106) and the second electrode plate (108), which resulting composite voltage will result in an electric field between the first (106) and the second electrode plate (108). The pumpable medium is exposed to the electric field.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: July 2, 2013
    Assignee: Arc Aroma Pure AB
    Inventor: Par H Henriksson
  • Patent number: 8459202
    Abstract: A gas flow of a gas pipe is indicated before an electromagnetic valve is actually opened, so that the electromagnetic valve can be prevented from being opened or closed by a wrong manipulation or hazards caused by undesired mixing of gases can be avoided so as to improve safety. The substrate processing apparatus includes a state detection unit configured to detect an opening/closing request state and an opening/closing state of a valve installed at a gas pipeline; and a indication unit configured to indicate a gas flow state of the gas pipeline predicted according to the opening/closing request state and a gas flow state of the gas pipeline when the valve is opened, in a way that each state is distinguished.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: June 11, 2013
    Assignee: Hitachi Kokusai Electronics Inc.
    Inventors: Tomoyuki Yamada, Mamoru Oishi, Kanako Kitayama
  • Patent number: 8351106
    Abstract: An optical micro-electro-mechanical systems (MEMS) structure is provided. The structure includes an elastomer membrane, a plurality of polymer fibers attached to the elastomer membrane, an array of detectors operatively connected to the plurality of polymer fibers at a first end of the plurality of polymer fibers, and a microlens array operatively connected to the plurality of polymer fibers at a second end of the plurality of polymer fibers. A method of manufacturing an optical MEMS structure is provided. The method includes forming a hollow PDMS chamber in which PDMS fibers extend from top to bottom using a lost wax molding process.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: January 8, 2013
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Jaeyoun Kim
  • Publication number: 20120273053
    Abstract: An ER fluid valve includes a housing and a plurality of parallel flow passages through the housing each defined by spaced electrodes at least one of which is controllable independently of other flow passages electrodes. A controller is configured to selectively establish electrical fields for all of the independently controllable electrodes to close all of the flow passages to ER fluid flowing through the housing. By removing the fields from all of the independently controllable electrodes, all the flow passages are open to the ER fluid flowing through the housing. By establishing fields for select independently controllable electrodes to close their associated flow passages and by leaving other flow passages open, restricted flow of the ER fluid through the housing is accomplished to vary the flow rate through the housing.
    Type: Application
    Filed: April 27, 2011
    Publication date: November 1, 2012
    Inventors: Michael P. Murphy, Robert Playter
  • Patent number: 8235072
    Abstract: A plasma actuator incorporates a power source, a first electrode in contact with a first dielectric layer, a second electrode in contact with a second dielectric layer, and a ground electrode. The power source drives the first electrode with a first ac voltage pattern with respect to the ground electrode to produce a first plasma discharge, and a first electric field pattern in the flow region, and drives the second electrode with a second ac voltage pattern with respect to the ground electrode to produce a second plasma discharge in the flow region and a second electric field pattern in the flow region. The first and second electrodes are offset along the direction of flow and the first voltage pattern and the second voltage pattern have a phase difference such that the first and second electric fields drive flow in different portions of the flow region at different times.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: August 7, 2012
    Assignee: University of Florida Research Foundation, Inc.
    Inventor: Subrata Roy
  • Publication number: 20120192952
    Abstract: A three-dimensional microfluidic system including: at least one hydrophilic thread along which fluid can be transported through capillary wicking; and at least one hydrophobic substrate for supporting the hydrophilic thread. A method of transporting and mixing a plurality of fluids within a microfluidic system including at least two hydrophilic threads and a hydrophobic substrate having at least two zones, each of the hydrophilic threads supported on a different hydrophobic substrate zone, including: delivering each said fluid to a different hydrophilic thread; and bringing the at least two hydrophilic threads into contact to cause mixing of the fluids.
    Type: Application
    Filed: July 20, 2010
    Publication date: August 2, 2012
    Applicant: Monash University
    Inventors: Wei Shen, Xu Li, David Robert Ballerini, Junfei Tian
  • Patent number: 8206994
    Abstract: The invention relates to a method for treating drops in a microfluid circuit, comprising at least one microchannel (12) through which the drops flow, characterized in that a laser (26) is brought to bear on the interface of said drops in the transport liquid (F3), or on the interface of drops in contact, in order to carry out a sorting of the drops, to form nanodrops from a larger drop or to fuse drops (60, 64) in contact and initiate reactions between the fluids contained in said drops.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: June 26, 2012
    Assignees: Centre National de la Recherche Scientifique, Ecole Polytechnique
    Inventors: Charles N Baroud, Jean-Pierre Delville
  • Patent number: 8201758
    Abstract: A fluid spraying device comprises a fluid oscillator used to oscillate fluid to generate spraying water and including an inlet, at least one power nozzle, an interacting chamber, and an outlet, characterized in that: the fluid oscillator including a first portion and a second portion; a connection of the first and the second portions communicates with the power nozzle to flow fluid through a predetermined traveling position, and the first portion includes the inlet and a section of the power nozzle, and the second portion includes the outlet and another section of the power nozzle, by using an interaction of the first and the second portions, a cross sectional area of the fluid at the connection of the first and the second portions is changed to adjust spraying water from the outlet.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: June 19, 2012
    Assignee: Globe Union Industrial Corp.
    Inventor: Meng-Feng Cheng
  • Patent number: 8127794
    Abstract: A dispenser arrangement for fluidic dispensing control into a microfluidic component comprising an enclosed fluid holding area having a base portion and a top portion and a valve adapted to be movable between an open position and a closed position and positioned at least partially in the fluid holding area. The valve comprises an elongated hollow portion having a body and two ends adapted for fluid flow from the fluid holding area to the microfluidic component in the open position, a first opening on the body of the hollow portion positioned within the fluid holding area allowing fluid communication from the fluid holding area to the microfluidic component in the open position, a sealing portion connected to a first end of the hollow portion positioned within the fluid holding area adapted for sealing connection with the top portion of the fluid holding area in the closed position and a slant second opening at a second end of the hollow portion positioned outside of the fluid holding area.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: March 6, 2012
    Assignee: Agency for Science, Technology and Research
    Inventors: Ling Xie, Chirayarikathuveedu Sankarapillai Premachandran, Ser Choong Chong
  • Patent number: 8104513
    Abstract: Disclosed is a gas flow path switching unit including a gas passage section with a target gas passage for allowing said target gas to pass therethrough. The target gas passage includes a main passage having a proximal end serving as said gas inlet and a number n of branch passages each provided with a respective gas outlet at a terminal end thereof. The branch passages are formed by repeating two or more times a branching process of branching said main passage into two sub passages at a branch point at a distal end of said main passage and further branching at least one of said sub passages into two sub-sub passages at a branch point defined by a distal end of said sub passage. The target gas passage also includes at least a number n of switching-gas supply passages connected to respective intermediate positions of said n branch passages.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: January 31, 2012
    Assignee: Shimadzu Corporation
    Inventor: Masanao Furukawa
  • Patent number: 8088267
    Abstract: Controlled electrokinetic transport of constituents of liquid media can be achieved by connecting at least two volumes containing liquid media with at least one dielectric medium with opposing dielectric surfaces in direct contact with said liquid media, and establishing at least one conduit across said dielectric medium, with a conduit inner surface surrounding a conduit volume and at least a first opening and a second opening opposite to the first opening. The conduit is arranged to connect two volumes containing liquid media and includes a set of at least three electrodes positioned in proximity of the inner conduit surface. A power supply is arranged to deliver energy to the electrodes such that time-varying potentials inside the conduit volume are established, where the superposition of said potentials represents at least one controllable traveling potential well that can travel between the opposing conduit openings.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: January 3, 2012
    Assignee: Tesla Laboratories
    Inventors: Patrick Ismail James, George Stejic
  • Patent number: 8012417
    Abstract: A microinjection device includes a pressure pump and a regulator that is connected to the pressure pump and that maintains constant pressure. A regulating chamber is connected to the regulator and an internal pressure of the regulating chamber is maintained to a predetermined pressure. A valve is connected to the regulating chamber and a hollow capillary is connected to the valve. An operator opens/closes the valve in the process of injecting material in a cell.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: September 6, 2011
    Assignee: Fujitsu Limited
    Inventors: Kiyoshi Taninaka, Jun Sasaki, Akihiko Yabuki
  • Publication number: 20110203671
    Abstract: A method and apparatus are disclosed for determining fluid flow in a flow path of a vortex amplifier. The method comprises the steps of preventing flow of control fluid in a direction substantially opposite to a primary direction of purge fluid flow in a purge flow path of a vortex amplifier.
    Type: Application
    Filed: October 22, 2009
    Publication date: August 25, 2011
    Inventor: Raymond Doig
  • Patent number: 8003062
    Abstract: A microchannel has a substrate body; a separation channel which is formed within the substrate; at least two (first and second) connection ports which are formed at one end of the separation channel close to the thickness direction perpendicular to the longitudinal direction of the substrate body; and first and second branch channels connected respectively to the first and second connection ports. When the substrate body is perpendicular to gravity, a blood sample containing blood cells and plasma, flows from one end of the separation channel. Before the blood sample gets to the other end of the separation channel, the blood cells in the blood sample settle out. The blood cells having settled out are then separated into the branch channel.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: August 23, 2011
    Assignee: Kyoto University
    Inventors: Hidetoshi Kotera, Masao Washizu, Hidehiro Oana
  • Publication number: 20100258046
    Abstract: A method and a device for suppression of cavitation and thus for reducing resistance to movement of a streamlined body in a flow of liquid based on the principle that development of cavitation bubbles in the area of separation of the flow that is accompanied by the development of turbulence is prevented by injecting a gaseous medium into the aforementioned area for separating the flow of liquid from the surface of the streamlined body. The device of the invention can be realized in the form of various specific embodiments with supply of gas under pressure to the cavitation-development area through a plurality of perforations and transverse slits.
    Type: Application
    Filed: May 17, 2007
    Publication date: October 14, 2010
    Inventors: Vladimir Berger, Sergey Sapronov
  • Publication number: 20100252118
    Abstract: Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply.
    Type: Application
    Filed: April 18, 2008
    Publication date: October 7, 2010
    Inventors: Seth Fraden, Hakim Boukellal, Yanwei Jia, Seila Selimovic, Amy Rowat, Jeremy Agresti, David A. Weitz
  • Patent number: 7803432
    Abstract: The present invention fundamentally differs from conventional methods in which an external force is directly applied to a surface of an article to be modified, and relates to a method of hydrophobilization (increasing a contact angle of water) which comprises bringing a hydrophobilization substance (a substance for increasing a contact angle of water) released from a material of another location into contact with a surface of an article, especially an article surface being hydrophilic (having a small contact angle of water) in its initial state without applying an external force on the article surface, further a method of control being capable of noncontact switching of a contact angle of water, which comprises conducting hydrophilization of an article surface subjected to hydrophobilization by the above-mentioned method in a noncontact manner and repeating these hydrophobilization and hydrophilization, and a method of pattern formation using the mentioned methods.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: September 28, 2010
    Assignees: Daikin Industries, Ltd., National Institute of Advanced Industrial Science and Technology
    Inventors: Junko Takahashi, Hidenori Nagai, Shinichi Wakida
  • Patent number: 7790109
    Abstract: A micro-fluid reaction vessel includes an upper plate formed of an elastomer, a lower plate adhered to the upper plate, a micro-chamber and a micro-channel formed on an inner surface of the upper plate facing the lower plate and an inlet hole and an outlet hole formed in the upper plate and through which a fluid flows into or out of, respectively. The micro-channel is constructed to be closed by pressure applied to the upper plate and elastically restored when the pressure is not applied. A micro fluid reaction method uses the micro fluid reaction vessel and a method of manufacturing forms the microfluid reaction vessel.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: September 7, 2010
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Su-hyeon Kim, Jin-tae Kim, Kak Namkoong, In-ho Lee, Chin-sung Park, Young-sun Lee
  • Publication number: 20100186840
    Abstract: Multi-valve autoregulatory microfluidic devices and methods are described. The described devices and methods offer improved performance and new means of tuning autoregulatory effects in microfluidic devices.
    Type: Application
    Filed: December 11, 2009
    Publication date: July 29, 2010
    Inventors: Emil P. KARTALOV, John LIU, Axel SCHERER, Clive R. TAYLOR
  • Publication number: 20100186839
    Abstract: A microfluidic valve unit for controlling the flow of fluid flowing along a channel, and a method of fabricating the same are provided. The valve unit includes a channel formed in a platform; a valve filler which includes a phase transition material that is disposed in the channel in a solid state at room temperature to close the channel and is melted when energy is applied thereto; and at least one capillary channel which extends from a sidewall of the channel and into which the valve filler flows when the valve filler is melted, wherein the at least one capillary channel has a cross-sectional area which is less than a cross-sectional area of the channel.
    Type: Application
    Filed: September 8, 2009
    Publication date: July 29, 2010
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Kak NAMKOONG, Won-seok CHUNG, Joon-ho KIM, Kyu-youn HWANG, Hee-kyun LIM
  • Patent number: 7748410
    Abstract: A first liquid fed into a first flow passage 6 of a fluid handling apparatus travels to the open end thereof on the side of a second flow passage 7 due to capillarity. The movement of the first liquid is uniformed on the cross section of the flow passage by the function of a capillarity promoting portion 220 or 230 of the bottom 21 of the first flow passage 6. Then, the movement of a second liquid fed into the second flow passage 7 is uniformed on the cross section of the flow passage by the function of the capillarity promoting portion 220 or 230 of the bottom 21 of the second flow passage 7. Thus, the movement of the front end of the second liquid is substantially uniformed to surely extrude gas from the second flow passage 7 to the outside via a fourth flow passage 10.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: July 6, 2010
    Assignee: Enplas Corporation
    Inventor: Koichi Ono
  • Patent number: 7731910
    Abstract: A microfluidic mixing assembly includes at least first and second liquid sources, a microfluidic manifold, a first capillary valve between the first liquid source and the manifold, and a second capillary valve between the second liquid source and the manifold, wherein the first capillary valve is configured to open and provide a first liquid flow to the microfluidic manifold in response to an external force and the second capillary valves is configured to be opened by the first liquid flow.
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: June 8, 2010
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Patrick V. Boyd, Philip Harding
  • Publication number: 20100101660
    Abstract: A channel switching system includes two microvalves i.e. a first valve (stopper valve) and a second valve (water retaining valve). The first valve is openable and closable, and the second valve is operable to block fluid flow by a surface tension force. Changing the first valve from an open state to a close state enables to switch the system from a condition that the fluid flows through the channel where the first valve is mounted by blocking the flow at the second valve by the surface tension force to a condition that the fluid flows through the channel where the second valve is mounted by releasing the system from the condition that the flow is blocked at the second valve by the surface tension force.
    Type: Application
    Filed: February 21, 2008
    Publication date: April 29, 2010
    Applicant: Konica Minolta Holdings, Inc.
    Inventors: Ken Kitamura, Toshihito Kido, Shinji Harada, Kenichi Miyata, Yasuhiro Sando
  • Publication number: 20100084032
    Abstract: A dispenser arrangement for fluidic dispensing control into a microfluidic component comprising an enclosed fluid holding area having a base portion and a top portion and a valve adapted to be movable between an open position and a closed position and positioned at least partially in the fluid holding area. The valve comprises an elongated hollow portion having a body and two ends adapted for fluid flow from the fluid holding area to the microfluidic component in the open position, a first opening on the body of the hollow portion positioned within the fluid holding area allowing fluid communication from the fluid holding area to the microfluidic component in the open position, a sealing portion connected to a first end of the hollow portion positioned within the fluid holding area adapted for sealing connection with the top portion of the fluid holding area in the closed position and a slant second opening at a second end of the hollow portion positioned outside of the fluid holding area.
    Type: Application
    Filed: September 19, 2006
    Publication date: April 8, 2010
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Ling Xie, Chirayarikathuveedu Sankarapillai Premachandran, Ser Choong Chong
  • Patent number: 7681595
    Abstract: Provided are a microfluidic device and a microfluidic network formed by connecting such microfluidic devices. The microfluidic device can equalize the flow of multiple microfluids in a chamber in parallel to thereby have an equal flow rate when the microfluids transferred through different flow channels join in the chamber having a changing cross-sectional area. The microfluidic device includes: multiple flow channels formed between an upper substrate and a lower substrate to transfer the microfluids and including inlets for injecting the microfluids in one side and fluid stopping surfaces for stopping the flow of the microfluids in the other side; a pressure controlling flow channel for removing a pressure difference between the microfluids; a fluid converging part for converging the microfluids; and a chamber composed of hydrophilic surfaces and hydrophobic surfaces disposed alternately in a flow direction so that the microfluids join and flow in parallel and equal.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: March 23, 2010
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sung-Jin Kim, Kwang-Hyo Chung, Hyeon-Bong Pyo
  • Publication number: 20090314368
    Abstract: A microfluidic system comprising a pneumatic or an hydraulic pinch valve. The pinch valve comprises: a microfluidic channel defined in a compliant body; an inflatable control channel cooperating with a valve section of the microfluidic channel such that pneumatic or hydraulic pressurization of the control channel causes inflation of the control channel and pinching closure of the valve section. The microfluidic system comprises an on-chip MEMS pump in fluidic communication with the control channel for pressurizing said control channel.
    Type: Application
    Filed: June 20, 2008
    Publication date: December 24, 2009
    Inventors: Gregory John McAvoy, Emma Rose Kerr, Kia Silverbrook
  • Publication number: 20090308473
    Abstract: Disclosed herein is a micro-fluidic chip including a hollow area into which a charged droplet is introduced, and an electrode configured to be provided toward the hollow area. Movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrode.
    Type: Application
    Filed: June 16, 2009
    Publication date: December 17, 2009
    Applicant: SONY CORPORATION
    Inventor: Masataka Shinoda
  • Publication number: 20090277521
    Abstract: An outlet nozzle (1) which can be attached to an outlet fitting, or to a similar outlet end of a sanitary water line, which includes a valve unit (3), which is displaceable between a blocking position, closing the water line, and an open position, releasing the water line, wherein at least one aerator unit having a jet divider, homogenizer, and/or flow rectifier, a shower unit, or similar jet former, is provided in the outlet nozzle (1). The outlet nozzle (1) is characterized by the low space requirement and production costs thereof.
    Type: Application
    Filed: July 13, 2007
    Publication date: November 12, 2009
    Applicant: NEOPERL GMBH
    Inventors: Christoph Weis, Oliver Denzler, Alexander Stein, Martin Fangmeier
  • Publication number: 20090235990
    Abstract: A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.
    Type: Application
    Filed: February 3, 2009
    Publication date: September 24, 2009
    Inventor: Neil Reginald Beer
  • Publication number: 20090165876
    Abstract: A fluid handling structure includes: an actuation area (03, 08) to control fluid flow within the structure; and a plurality of actuation components (09, 11, 12, 13) within the actuation area (03, 08); wherein the actuation area (63, 68) is constructed and arranged to activate or control each of the plurality of actuation components (09, 11, 12, 13). A fluid handling structure comprising: a fluid channel (204); and a deformable material (202); wherein the fluid channel is bounded, at least in part, by the deformable material (202). A fluidic device comprising: at least one channel (403) defining a path for the travel of an electromagnetic wave. A method of performing a function with an instrument, the method comprising: associating an insert with the instrument, the insert comprising one or more of program code, data, or commands, which enable performance of the function.
    Type: Application
    Filed: November 22, 2006
    Publication date: July 2, 2009
    Inventors: Micah James Atkin, Gregory Francis Eaton
  • Publication number: 20090145485
    Abstract: According to one embodiment, an apparatus and method for delivering one or more fluids to a microfluidic channel is provided. A microfluidic channel is provided in communication with a first conduit for delivering fluids to the microfluidic channel. Further, the apparatus and method can include a first fluid freeze valve connected to the first conduit and operable to reduce the temperature of the first conduit for freezing fluid in the first conduit such that fluid is prevented from advancing through the first conduit.
    Type: Application
    Filed: August 10, 2006
    Publication date: June 11, 2009
    Applicant: EKSIGENT TECHNOLOGIES, LLC
    Inventors: Gregory Fenton Smith, Dawn M. Schmidt, Sara Thrall, David G. Tew, Gregory A. Votaw, Hugh C. Crenshaw, Michael G. Pollack, Christopher David Bevan, Kelly Junge, Mehul Patel
  • Patent number: 7539560
    Abstract: Valve positioning systems may include one or more components and a controller. Components may include one or more electric-to-pressure output converters, relays, gas supplies, and/or actuators. A controller may adjust a position of a valve by sending a signal. The valve positioning system may individually monitor components and determine the condition of each component being individually monitored. The valve positioning system may determine if a component will fail prior to failure and/or determine if a problem will occur in a component prior to the problem occurring.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: May 26, 2009
    Assignee: Dresser, Inc.
    Inventors: Henry W. Boger, Sandro Esposito
  • Patent number: 7517440
    Abstract: A method of pumping fluid including the steps of providing an electrokinetic pump comprising a pair of double-layer capacitive electrodes having a capacitance of at least 10?2 Farads/cm2 and being connectable to a power source, a porous dielectric material disposed between the electrodes and a reservoir containing pump fluid; connecting the electrodes to a power source; and moving pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump. The invention also includes an electrokinetic pump system having a pair of double-layer capacitive electrodes having a capacitance of at least 10?2 Farads/cm2; a porous dielectric material disposed between the electrodes; a reservoir containing pump fluid; and a power source connected to the electrodes; the electrodes, dielectric material and power source being adapted to move the pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump.
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: April 14, 2009
    Assignee: Eksigent Technologies LLC
    Inventors: Deon S. Anex, Phillip H. Paul, David W. Neyer, Edwin J. Hlavka
  • Patent number: 7473397
    Abstract: A device for analysis of a sample, the device comprising: a first layer having a network of passages and chambers through which fluid is caused to flow during analysis; a second layer in which a plurality of chambers are formed, the chambers containing fluids for use in the analysis; an inlet in either the first or the second layer into which a sample to be analysed can, in use, be placed, and a third layer providing a frangible fluid seal between the chambers of the second layer and the network of the first layer so that, in use, a break in the third layer permits fluid from a chamber in the second layer to pass into the network of the first layer to enable analysis of the sample to be carried out.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: January 6, 2009
    Assignee: The Technology Partnership PLC
    Inventors: Neil Griffin, Nicki Sutton, Allan Carmichael, Sam Charles William Hyde, John Matthew Somerville
  • Patent number: 7418977
    Abstract: A liquid-handling apparatus has a liquid switch, which has a first channel branching into a second and a third channel, wherein the channels are formed in a rotation body. The channels are adapted to route a liquid volume from the first channel into one of the second channel and the third channel dependent on whether a Coriolis force and/or an Euler force prevails a centrifugal force or not. A liquid-handling apparatus having such a liquid switch is particularly suited for applications in which different volumes of liquid have to be passed through a stationary phase.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: September 2, 2008
    Assignee: Albert-Ludwigs-Universitaet
    Inventors: Jens Ducreé, Roland Zengerle, Thilo Brenner, Thomas Glatzel
  • Patent number: 7316859
    Abstract: A hydrogen storage system and method having a main hydrogen storage site that contains a sufficient amount of hydrogen for a fuel cell employing a polymer membrane to generate power in accordance with a predetermined electrical power requirement. A main storage site is provided to store and supply hydrogen to meet the electrical power requirement for the fuel cell. An auxiliary hydrogen storage site contains a sufficient amount of hydrogen to allow the fuel cell to operate on a scheduled basis that is required to maintain the polymer membrane hydrated. A manifold connects the main and auxiliary hydrogen storage sites and has an outlet to deliver hydrogen to the fuel cell. The manifold allows the auxiliary hydrogen storage site to be renewed independently of the main storage site and has a flow control network to allow the fuel cell to draw hydrogen from the auxiliary hydrogen storage site for maintenance purposes without utilization of the hydrogen from the main hydrogen storage site.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: January 8, 2008
    Assignee: Praxair Technology, Inc.
    Inventors: Gervase Maxwell Christie, James Joseph Volk, Timothy James Fagan
  • Patent number: 7314567
    Abstract: In the method for mixing-free transport of homogeneous liquids in microchannels a heterogeneous liquid flow (14) is autonomously divided into portions, transported over a distance and then autonomously recombined. When the flow is divided into portions, individual volumes of a second liquid (16), which may be but must not be homogeneous, are introduced between volume fractions lying one behind the other of the heterogeneous liquid flow (14). While the volume fractions of the heterogeneous liquid (14) that lye close to one another would mix with each other without this measure being taken, separation of the individual volume fractions allows these volume fractions, and thus the heterogeneous liquid (14), to be transported over large distances without any mixing occurring.
    Type: Grant
    Filed: May 26, 2003
    Date of Patent: January 1, 2008
    Assignee: ProtoLife Srl.
    Inventors: Patrick Wagler, John Simpson McCaskill, Tobias Foster
  • Patent number: 7171983
    Abstract: Improved microfluidic devices, systems, and methods allow selective transportation of fluids within microfluidic channels of a microfluidic network by applying, controlling, and varying pressures at a plurality of reservoirs. Modeling the microfluidic network as a series of nodes connected together by channel segments and determining the flow resistance characteristics of the channel segments may allow calculation of fluid flows through the channel segments resulting from a given pressure configuration at the reservoirs. To effect a desired flow within a particular channel or series of channels, reservoir pressures may be identified using the network model. Viscometers or other flow sensors may measure flow characteristics within the channels, and the measured flow characteristics can be used to calculate pressures to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems can optionally be used in conjunction with electrokinetic or other fluid transport mechanisms.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: February 6, 2007
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Ring-Ling Chien, J. Wallace Parce, Andrea W. Chow, Anne Kopf-Sill
  • Patent number: 7134453
    Abstract: The invention relates to a microfluidic switch for stopping a liquid flow during a time interval with the following features: the switch has at least one first channel and at least one second channel; the first channel and the second channel have a common end area; the first channel in the end area has a stopping mechanism for stopping of a liquid flow flowing in the first channel; the stopping mechanism can be controlled by means of a liquid flow flowing in the second channel for continuing the liquid flow in the first channel. Transport in the first and the second channel takes place advantageously by the capillarity acting in the channel.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: November 14, 2006
    Assignee: Boehringer Ingelheim Microparts GmbH
    Inventors: Ralf Peters, Gert Blankenstein, Holger Bartos, Claus Marquordt