Abstract: In a method and with a circuit for operating a nitrogen oxide sensor for determining the nitrogen oxide (NOx) concentration in a gas mixture, in particular in post-treatment of an automotive exhaust, an electric pumping voltage (U_APE,IPE) which induces a pumping current (I_pump) being applied between an internal pump electrode (IPE) and an external pump electrode (APE) of a pumping cell, by which a constant oxygen partial pressure is established in a first test gas space by pumping oxygen in or out, the pumping voltage (U_APE,IPE) being regulated so that a constant voltage value is established at electrodes of a concentration cell, a NOx-sensitive third electrode situated in a second test gas space being operated as the second pumping cell in which a limit pumping current is established, indicating the NOx concentration, in order to minimize the influence of oxygen on the nitrogen oxide signal measured, the pumping current (I_pump) is switched off or reduced in a controlled manner within a measurement time w

Abstract: Soot sensing systems and soot sensors are provided. In one exemplary embodiment, a soot sensor includes a non-conductive substrate and a first electrode disposed on the non-conductive substrate. The soot sensor further includes a second electrode disposed on the non-conductive substrate and spaced away from the first electrode. The soot sensor further includes a first protective layer disposed over at least a portion of the first electrode. The soot sensor further includes a second protective layer disposed over at least a portion of the second electrode. Further, an electrical parameter between the first and second electrodes is indicative of an amount of soot disposed on the non-conductive substrate between the first and second electrodes.

Abstract: Disclosed is a method of driving an electrophoretic device that includes an electrophoretic element having a first electrode, a second electrode, and an electrophoretic layer disposed between the first and second electrodes, and further includes a capacitor connected to the first electrode at one terminal. The method includes (a) applying a reference potential or a first potential higher than the reference potential to the first electrode of the electrophoretic element and the terminal of the capacitor and applying the reference potential to the second electrode of the electrophoretic element, and (b) applying a signal fluctuating between a second potential and a third potential to the second electrode subsequently to the step (a), the second potential being equal to or higher than the reference potential, the third potential being higher than the second potential and being equal to or lower than the first potential.

Abstract: An analysis device for analysis of a sample on a test element is provided that comprises at least one component configured to make electrical contact with at least one other component for electrical transmission therebetween. The at least one component generally comprises an injection-molded circuit mount, also called an MID, or molded interconnect device.

Abstract: A sensor control device for controlling a current application state of a gas sensor element when measuring a specific gas component concentration in a gas to be measured using the gas sensor element, which sensor control device includes: at least one cell having a solid electrolyte body and a pair of electrodes; a sensor heating unit as defined herein; an oxygen reference pole generating unit as defined herein; a damage avoidance time elapse determining unit as defined herein; and a reference generation current application permitting unit as defined herein.

Abstract: An oxygen sensor for measuring exhaust gases of an internal combustion engine is described. The sensor provides an output that has a high gain near the stoichiometric air-fuel ratio, and a lower gain in the lean and rich air-fuel ratio regions. Further, the sensor provides wide range air-fuel ratio signal to be used in engine feedback control.

Abstract: In a gas concentration detecting apparatus, a voltage is applied to electrodes of a sensor element. A change is caused in either the applied voltage or an element current. An amount of a change in each of a current value and a voltage value caused is measured in response to the caused change. An amount of resistance of the sensor element is calculated based on a ratio between the change amounts in the current value and the voltage value. A detection unit detects abnormality relating to controlling the sensor by utilizing at least one of the change amounts in the current value and the voltage value.

Abstract: An easily calibrated analytical instrument for sensing a target analyte. The instrument includes an electrochemical sensor and a switch. The electrochemical sensor includes a sensing electrode and a counter electrode. The switch is a normally open switch effective for creating a short circuit between the sensing and counter electrodes when closed. A zero calibration reading can be taken when the switch is closed.

Abstract: An electrochemical drive circuitry and method, such as may be employed in electroplating bath chemical monitoring. A microcontroller can be utilized to selectively apply galvanostatic or potentiostatic conditions on the electrochemical cell, for measurement of response of the electrochemical cell to such conditions, with the microcontroller arranged to generate an offset potential to control potential across the electrochemical cell within a range of potential accommodated by a unipolar power supply, and/or a CMOS analog switch can be employed in combination with individual digital-to-analog converters for each of the current-controlled and potential-controlled conditions, to provide high-speed, dual mode operating capability.

Abstract: In a gas concentration measuring apparatus, a measurement substrate is provided. A conductive pattern portion is formed in the measurement substrate. The conductive pattern portion includes a signal input pattern constituting the signal processing circuit and electrically connected to the connection terminal, said signal input pattern having direct current impedance with respect to the connection terminal, said direct current impedance being 10 percent or less of the input impedance of the connection terminal; a different potential pattern having a potential difference of 2 V or over from a potential of the signal input pattern; and a guard pattern having a substantially constant potential and a potential difference of less than 0.5 V from the potential of the signal input pattern, said guard pattern being arranged on at least a portion of the measurement substrate, said at least portion of the measurement substrate being located between the signal input pattern and the different potential pattern.

Abstract: An oxygen sensor is employed for determining whether the exhaust air-fuel ratio is rich or lean. A voltage is applied to the oxygen sensor at device impedance calculation intervals to calculate device impedance. After device impedance calculation, a reverse voltage is applied to the oxygen sensor with a view toward promptly negating the influence of voltage application on the sensor output. Subsequently, the sensor output of the oxygen sensor is sampled at sampling time intervals until it is concluded that the device impedance calculation period is over.

Abstract: A method of monitoring an electrochemical second order half-cell (1, 101) is provided, as is a measuring probe with at least one electrochemical second order half-cell (101), a control- and/or regulation unit (7) to close an electrochemical contact between the half-cell and a measuring medium (8), and with at least one temperature sensor (9, 10). The half-cell includes an electrolyte (4) and a first conductor element (2) in contact with the electrolyte and which holds a first electrical potential (E1). The half-cell also has a second conductor element (3) in contact with the electrolyte, the second conductor holding a second electrical potential (E2). The two conductor elements (2, 3) comprise the same metal. The first conductor element has a coating (6) of a low-solubility salt of the same metal. The control- and/or regulation unit includes a program for executing a method of monitoring the electrochemical half-cell.

Abstract: An apparatus and method for detecting ionic materials includes a sensing electrode which contacts a liquid sample and detects a sensing voltage corresponding to a surface potential which is changed by a concentration of ionic materials in the liquid sample, a first switching transistor having a first terminal connected to the sensing electrode and a second terminal connected to a first node, a second switching transistor having a first terminal connected to a reset voltage and a second terminal connected to the first node, and a sensing transistor having a gate connected to the first node.

Abstract: The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array includes an array of electrodes coupled to sample-and-hold circuits. The programmable multiplexed active biologic array includes a digital interface that allows external control of the array using an external processor. The circuit may monitor, digitally control, and deliver electrical stimuli to the electrodes individually or in selected groups.

Abstract: In order to follow the change in concentration of a redox-active substance, potential suitable for a reducing process or oxidation process are applied to the working electrode of a measuring device. The potential of the working electrode is pulsed and measuring phases and relaxation phases are alternately produced, the pulse lengths of the measuring phase and relaxation phase being predetermined in a suitable manner. In this manner, a rapid relaxation of the concentration gradient is forced electrochemically so that the measurement can be carried out on simple transducer arrays. The device includes a transducer array in addition to a suitable potentiostat. The transducer array may include a planar metal substrate on which at least one flexible insulator having a firm connection between the metal surface and the insulator surface is located. The array is generated by suitably structuring the substrate.

Abstract: A method and apparatus for provide a stable voltage to an electrochemical cell used for measurement of an analyte such as glucose in a liquid sample. The apparatus uses a circuit in which multiple switching positions provide both calibration information for use in calibration of electronic components in the circuit and error checking functionality.

Abstract: A quantitative analyzing method is provided for electrochemically measuring the concentration of a substance in a sample liquid using a sensor including a reagent layer (30) which contains a reagent for reacting with the substance and to which (30) the sample liquid is introduced, and a first electrode (22) and a second electrode (23) for applying a voltage to the reagent layer (30). The method includes a current measuring step for applying a voltage across the first electrode (22) and the second electrode (23) for measuring current flowing between the first and the second electrodes (22,23), a parameter calculating step for calculating a parameter based on the measured current, and a determining step for determining a state of the sample liquid introduced to the reagent layer (30) based on the parameter and at least one predetermined constant.

Abstract: The present invention relates to a biosensor requiring no code card, which can be substantially a glucose monitor having a top key, a bottom key and a confirmation key arranged thereon for using the aforesaid top and bottom keys to control and select a set of English alphabet or numeral in a circulating manner and thereafter confirming and inputting a specific series of alphabets or numerals by pressing the confirmation key, whereas the specific series of alphabets or numerals is corresponding to a set of parameters stored in a parameter referencing unit arranged inside the glucose monitor and can be find on the package of a test strip. As soon as the specific series of alphabets or numerals is inputted into the glucose monitor, the set of parameter corresponding thereto is send to a micro processing unit for using the same to perform a setting and calibration operation so as to enhancing the accuracy of the glucose monitor.

Abstract: A system of measuring pH of a solution having a calibration device to counteract time-drift effect. The calibration device of the system adjusts a compensation voltage to zero a measuring voltage of a first sensor and only respond to time-drift voltage of the first sensor. The calibration device has a differential operation amplifier receiving measuring voltages from the first sensor and a second sensor of the system to eliminate the time-drift voltages of the first and second sensors, thereby achieving calibration of the time-drift effects.

Abstract: A sensor dispensing instrument adapted to handle a sensor pack containing a plurality of sensors and to perform a test using one of the sensors. The sensor dispensing instrument includes an outer housing and display disposed on the outer housing for showing items. The sensor dispensing instrument further comprises a power button for turning the sensor dispensing instrument on and off, a scroll button for scroll through the items, and a select button for selecting an item.

Abstract: According to one embodiment, the gas sensor includes a porous plate-like sintered body comprising trisilicon tetranitride needle crystals; two first catalyst metal thin films and one second catalyst metal thin film, formed on one surface of the plate-like sintered body in a non-contacted state with each other; oxygen ion-conductive solid electrolyte thin films formed on the respective surface; a surface layer thin film formed on the respective surfaces, so that a first measurement part, a second measurement part and a third measurement part are constituted; and a glass sealing layer comprising silicon oxide, formed on other surface of the porous plate-like sintered body, a surface other than the surface of the porous plate-like sintered body having the first catalyst metal thin film and the second catalyst metal thin film formed thereon, and a side of the first measurement part and the second measurement part.

Abstract: The invention is directed to devices and methods that allow for simultaneous multiple biochip analysis. The method of analyzing the plurality of biochips includes inserting a first biochp into a first station of an analysis device, inserting a second biochip into a second station of the analysis device, wherein each of the first and second biochips include a substrate, the substrates including an array of detection electrodes, each electrode including a different capture binding ligand, a different target analyte, and a label, and a plurality of electrical contracts, detecting current as an indication of the presence of the labels on the first biochip, and detecting current as an indication of the presence of the labels on the first second biochip. The devices and method may be used with multiple cartridges comprising biochips comprising arrays, such as nucleic acid arrays, and allow for high throughput analysis of samples.

Abstract: An interface device for a gas sensor includes a detection resistor having first and second ends to generate voltages by a current output of the gas sensor, a differential amplifier having first and second input terminals to receive the voltages of the first and second resistor ends and an output terminal to output a voltage according to a difference between the voltages of the first and second resistor ends, a first switching element to transmit the voltage of the first resistor end to the first input terminal of the differential amplifier in a transmission state and interrupt transmission of the voltage of the first resistor end to the first input terminal of the differential amplifier in an interruption state and a second switching element turned on to establish continuity between the first and second input terminals of the differential amplifier when the first switching element is in the interruption state.

Abstract: A gas detector with a compensated electrochemical sensor exhibits altered sensitivity in response to decreasing stochastic noise in an output thereof. A gain parameter can be adjusted to alter sensitivity. A life-time estimate can be made based on sensitivity.

Abstract: The invention relates to a method and device for the monitoring of a medical microsample in the flow measuring cell of an analyzer with regard to position and absence of bubbles by means of an alternating voltage applied to the measuring cell, the measuring cell being provided with a multitude of electrode systems placed one behind the other, each system comprising a number of single electrodes for measuring a substance contained in the microsample by means of a measurement voltage which essentially is a DC voltage. To monitor the exact position of the microsample and/or to detect air bubbles in the area of each electrode system, the alternating voltage and the measurement voltage are simultaneously and directly applied to the single electrodes of the corresponding electrode system, and the measured AC component respectively the measured impedance gives a measure for the position of the microsample and the absence of bubbles.

Abstract: An electronic sensor is provided for detecting the presence of one or more analytes of interest in a sample. The sensor preferably comprises a field effect transistor in which conductance is enhanced by analyte binding to receptors in the active region. An array of sensors may be formed to analyze a sample for multiple analytes.

Abstract: The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array includes an array of electrodes coupled to sample-and-hold circuits. The programmable multiplexed active biologic array includes a digital interface that allows external control of the array using an external processor. The circuit may monitor, digitally control, and deliver electrical stimuli to the electrodes individually or in selected groups.

Abstract: An analyzer measures the concentration of a specific component in a sample liquid supplied to a test piece equipped with first and second terminal parts. An analyzer (X1) includes a stage on which a test piece is placed, a first terminal (40a) for electrical connection with a first terminal part, a second terminal (40b) for electrical connection with a second terminal part, and an electric circuit (6) for measuring parameters required for calculating the concentration of a specific component. A check piece (4?), in place of the test piece, is placed on a stage to test the electric circuit (6). The test of the electric circuit (6) is performed based on a plurality of electric responses from the electric circuit (6) with a plurality of electric conditions applied to the check piece (4?).

Abstract: The present invention provides a packaging structure of a gas detector and the method for making the same. The packaging structure of the gas detector includes a printed circuit board, a detection device and a ventilation cover. The detection device is attached to the printed circuit board by adhesive, and metallic wires are formed on the printed circuit board by wire-bonding process. The ventilation cover is positioned at the printed circuit board to cover the detection device. Signal terminals of the detection device are electrically connected with the contact terminals of the printed circuit board so as to test and check signals of the detection device. In this regard, the present invention is used to test and package a plurality of detection devices using one printed circuit board and without metallic terminals so that cost of the gas detector is significantly reduced.

Abstract: A gas detector with a compensated electrochemical sensor exhibits altered sensitivity in response to decreasing sensitivity relative to both gas exposure and non-gas exposure. A sensitivity adjustment can be established in response thereto.

Abstract: A biosensor, a measuring instrument for biosensor, and a method of quantifying a substrate contained in specimen liquid to reduce a measurement error by the biosensor; a biosensor, comprising at least a pair of electrodes formed on an insulation substrate; a measuring instrument, comprising a supporting part for detachably supporting the biosensor, a plurality of connection terminals electrically connected to the electrodes, and a drive power supply for applying a voltage to the electrodes through the connection terminals; wherein the biosensor is inserted into the measuring instrument, either one of the electrodes of the biosensor is connected to first and second connection terminals fined to the measuring instrument only when the biosensor is inserted into the support part of the measuring instrument in a specified direction and has an electrode structure to allow the first connection terminal to conduct with the second connection terminal when a voltage is applied by the drive power supply.

Abstract: A biological material detection apparatus which detects a charged biological material such as a gene or protein contained in a sample liquid is disclosed. A biological material detection element includes a substrate, at least one first electrode formed on the substrate, and a plurality of second electrodes which are arrayed at predetermined intervals around the first electrode on the substrate along the circumferential direction and to which ligands that react with predetermined biological materials are respectively immobilized. A sample liquid is introduced toward the first electrode on the substrate. The introduced sample liquid is moved radially toward the second electrodes by electrical control.

Abstract: An electronic sensing circuit for an electrochemical gas sensor cell providing high dynamic range is described. The electronic circuit utilizes an amplifier with a resistive feedback element to provide high sensitivity linear sensing of low detected gas concentrations. The electronic circuit also provides the ability to source sufficient current to prevent the electrochemical gas sensor cell from becoming biased under very high gas concentration conditions. This operation is enabled by adding a non-linear element in the feedback path of the amplifier, which non-linear element begins to conduct during the high gas concentration conditions.

Abstract: A process and a device are provided for monitoring the hydrogen concentration in a gas with at least one device, which comprises an electrochemical gas sensor and a bipotentiostat, e.g., for use in internal combustion engines with hydrogen, in fuel cells and in the petrochemical industry. The electrochemical gas sensor used has two working electrodes (3) and (4), with which the hydrogen and oxygen concentrations are determined in the gas in different steps due to the application of a voltage by a bipotentiostat (5-18). In an additional, optional step, a voltage in the range of ?1,100 mV to ?800 mV is applied to a working electrode (4), so that hydrogen is formed at the working electrode (4) and the functional surface of the working electrode (4) as well as the sensitivity of the working electrode (3) to hydrogen can be checked.

Abstract: The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples.

Abstract: A compensation circuit (KS) is provided between the output of a differential amplifier (Diff_Amp) and the input of a controller (R). The compensation circuit generates a compensation signal, whose characteristic curve approximates to that of the parasitic signal, with the same amplitude and frequency (Phi1) as the parasitic signal, but by 180 DEG out of phase. The compensation signal is subtracted from the differential signal (DELTA Vs) and allows the parasitic signal to be eliminated to a great extent.

Abstract: Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.

Abstract: An improved engine control system using a NOx sensor is disclosed. In one example, the NOx sensor structure and/or signals are modified to improve distance transmission of NOx sensor output signals so that at least some processing electronics can be relocated remote to the sensor and in an engine control unit, or other such control unit utilizing the NOx sensor signals, and controlling the NOx sensor heaters, if applicable.

Abstract: A method for analyzing a papermaking process is disclosed in which several electrochemical quantities are measured from at least one liquid flow and fingerprints according to good process situations are determined. The electrochemical measurements are carried out independently of each other using at least three electrode series, each including at least three electrodes. In addition, at least one odor measurement is used from the gases that are emitted from the liquid flow into the gas space over the free liquid surface.

Abstract: A system for detecting an isolation fault in a multi-stack fuel cell system. The system determines the percentage of the voltage from each stack in the multi-stack that contributes to the voltage at a positive terminal and a negative terminal of the stack when a no-fault condition exists. The system then uses those percentages and the actual measured stack voltages to determine if a fault condition exists. The actual voltage measurement at the positive terminal is compared to the calculated voltage contribution from each stack at the positive terminal for the no-fault condition. Also, the actual voltage measurement at the negative terminal is compared to the calculated voltage contribution from each, stack at the negative terminal for the no-fault condition. If there is a significant enough different between the calculated voltage for a no-fault condition and the calculated percentage of the actual voltage measurements, than a fault condition exists.

Abstract: The pumping current source (P) required for operating the linear lambda probe is wired in such a manner that its inverting input is connected to the third probe terminal (Vp+), its non-inverting input is connected to the potential of the mean voltage (VM), and that its output is connected to the second probe terminal (Vp?/Vs?).

Abstract: A system for conducting a plurality of different medical diagnostic tests comprises a hand-held portable self contained instrument for engaging a disposable test cell containing a fluid to be tested. The instrument performs a diagnostic test selected from the plurality of tests upon the fluid within the test cell, the test being selected by the instrument based upon identification information obtained from the test cell. A disposable, single use test cell is provided for receiving fluid to be diagnostically tested. The test cell includes identification information indicative of a particular test to be performed upon the fluid, the test cell being sized and shaped for engagement by the instrument.

Abstract: A device according to the present invention is provided with element temperature measurement voltage application circuit for temporarily applying a predetermined voltage for element temperature measurement to a sensor element of an air-fuel ratio sensor equipped to an exhaust system of an internal combustion engine, first sensor output reading circuit for reading in a sensor output just before applied with the voltage, and second sensor output reading circuit for reading in a sensor output being applied with the voltage, wherein the element temperature of the air-fuel ratio sensor is estimated based on the sensor output just before applied with the voltage and the sensor output being applied with the voltage. Further, during internal resistance measurement of the sensor element of the air-fuel ratio sensor equipped to the exhaust system of the internal combustion engine, a voltage applied to the heater for heating the sensor element is maintained to be constant.

Abstract: The present invention relates to methods to increase the number of analyte-related signals used to provide analyte measurement values, e.g., when two or more analyte-related signals are used to obtain a single analyte measurement value a “rolling” value based on the two or more signals can be employed. In another aspect, interpolation and/or extrapolation methods are used to estimate unusable, missing or error-associated analyte-related signals. Further, interpolation and extrapolation of values are employed in another aspect of the invention that reduces the incident of failed calibrations. Further, the invention relates to methods, which employ gradients and/or predictive algorithms, to provide an alert related to analyte values exceeding predetermined thresholds.

Abstract: A chemical sensor for detecting the presence of one or more analytes. The sensor comprises at least one electrode pair and a photopolymerized electrically conducting polymer composition disposed in contact between each of the electrode pairs. Each polymer composition may include an organic polymer capable of interacting with one or more analytes. The sensor also comprises a means for delivering an analyte to each polymer composition, and a means for processing the resultant electronic signal from each polymer composition and electrode pair. Preferably, the sensor comprises a plurality of different polymer compositions, each with a dedicated electrode pair, to generate a collection of signals that provide a fingerprint unique to a particular analyte.

Abstract: The invention relates to a sensor for measuring ion concentration or gas concentration, with a gas- or ion-sensitive layer (6) that has two sensitive partial areas (20 and 21), two conducting areas (1b and 2b), each coupled capacitively through air gaps (9and 10) with one of the sensitive partial areas (20 and 21), with the capacitances of the couplings being different, and a comparison circuit (1a, 2a, 3, 4, 5) which has at least one first transistor (T1) connected with the first conductive area and a second transistor (T2) connected with the second conductive area, and at least one output at which a signal can be tapped that depends on the potential of sensitive layer (6).

Abstract: An Electrochemical biosensor readout meter which can do selectively quantitative analysis of sample of living body such as blood sugar, cholesterol and other elements in blood is disclosed. It is an object of this invention to provide electrochemical biosensor readout meter which has no distortion in peak current and can be manufactured in a low cost. In a preferred embodiment of present invention, a voltage converting means (OP2) is set to convert peak current which occurs at 3rd voltage applying time (t3) into voltage with no distortion and an amplifier (OP3) is set to make digital voltage signal at measuring time (t4) lower than reference voltage of A/D converter.

Abstract: The present invention relates to a high through-put system for determining and/or monitoring electrophysiological properties of ion channels of ion channel-containing membranes, typically lipid membrane-containing structures such as cells. In particular, the invention provides a substrate which provides means for automatically positioning cells at measuring sites using electroosmotic flow in canals formed on or in the substrate. The electroosmotic flow is generated and controlled by electroosmotic flow pumps integrated on the substrate or positioned in relation thereto. Thereby, cells can be positioned in favorable measurement configuration at a plurality of sites for performing testing and measurements. Also, the invention relates to a main electric circuit for performing testing and measurements on a plurality of cells in parallel.

Abstract: This invention provides approaches to improve the signal to noise ratio (S/N) in electrochemical measurements (e.g. amperometry, voltammetry, etc.). In particular, a method is described wherein the faradaic current is temporally dissociated from the charging current associated with reading the charge of a redox-active species (e.g. a self-assembled monolayer (SAM)). This method, designated herein as open circuit potential amperometry (OCPA), quantitatively reads the charge of the redox species bound to (electrically coupled to) an electrode surface, while discriminating against both charging current(s) and amperometric signal(s) that arise, e.g. from diffusion-based species in solution.

Abstract: A method and device for driving a gas sensor includes a three-point circuit determining a temperature of a gas sensor having a resistive heating element by determining a measuring current with a measuring resistor flowing through the resistor in a measuring phase. The three-point measurement makes it possible to determine accurately the line resistance of an incoming line branch, which can also be used approximately for the line resistance of another incoming line branch. Naturally, the tap may also be provided on the incoming line side.