Abstract: Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).

Abstract: Disclosed are heterocyclic compounds of the formula and the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, T, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptor.

Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, wherein A is selected from NCN, NCONH2, and NOR9. The present invention relates to compounds which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: A temperature control medicine carrying case having an insulated housing, a plurality of interior compartments, an interior pouch, a cooling mechanism and a fastening mechanism, e.g., a zipper closure. The interior surface of the insulated housing comprises two separate portions that are separated along a central axis. The interior pouch is located on a first portion of the interior surface of the insulated housing. The interior pouch is adapted to receive the cooling mechanism. At least one of the interior compartments is located on the exterior surface of the interior pouch and is adapted to receive a container of medicine. A plurality of interior compartments is located on the second portion of the interior surface. These compartments are adapted to receive medical devices that are used for administration of the medicine.

Abstract: A package for dispensing articles intended for one time use only, such as skin plasters or adhesive bandages, medicaments, and disposable handkerchiefs, where the articles are placed on top of each other, or on top of and side-by-side of each other, to form a layer of juxtaposed articles. The package includes an upper part and a lower part that is partially telescopically received within the upper part. The lower part of the package is generally rectangular in cross-section and is closed at its bottom and along its sides to form a pocket. The rear wall of the lower part connects with the front edge of a flat panel defining a top wall of the upper part. A tongue extends from the front edge of the upper part down between the respective rear wall and front wall of the lower part of the unit.

Abstract: This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I The invention is particularly related to such compounds that bind with high selectivity and high affinity to the benzodiazepine site of GABAA receptors. This invention also relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in treatment of certain central nervous system (CNS) diseases. Novel processes for preparing compounds of Formula I are disclosed. This invention also relates to the use of benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds of Formula I in combination with one or more other CNS agents to potentiate the effects of the other CNS agents. Additionally this invention relates to the use such compounds as probes for the localization of GABAA receptors in tissue sections.

Abstract: A package assembly holds at least one applicator nozzle tip and, optionally, a fluid-containing vial adapted for attachment to the nozzle tip. By providing the vial with a fluid-dispensing end, it may be used with or without the nozzle tip. When used in combination, the vial and nozzle tip can be employed to dispense, for instance, a medical adhesive to a wound site.

Abstract: A storage box that can be attached to a patient's bed rail. The box has a number of slots, cavities, and hooks that can be used to hold a wide range of medical equipment. Unlike the devices mentioned above, this device allows practitioners to hold items larger than tubes and more specific than medicine jars in one container. Moreover, the container has shaped cavities that make sorting of the equipment easy and fast. Finally, the shaped cavities also ensure that the proper equipment is used and placed in the proper location to reduce the chance of error in the administration of various treatments.

Abstract: A surgical kit is provided for a “pull” percutaneous endoscopic gastrostomy (PEG) procedure. The kit includes offset planar surfaces and at least one article recess defined in the planar surfaces. The recesses are adapted to hold at least one article used in performing a “pull” PEG procedure.

Abstract: A surgical kit is provided for a “push” percutaneous endoscopic gastrostomy (PEG) procedure. The kit includes offset planar surfaces and at least one article recess defined in the planar surfaces. The recesses are adapted to hold at least one article used in performing a “push” PEG procedure.

Abstract: A surgical kit, for example a percutaneous endoscopic gastrostomy kit, includes a tray having a plurality of recesses formed therein for receiving surgical implements. A substantially rigid accessory item container is received in a container recess defined in the tray. The container is removable from the tray and includes a base member and a lid. A securing device may be configured between the base member and the lid so that the container is reclosable.

Abstract: The present invention provides a method for detecting chitin-containing organisms on an area of a person or animal by contacting the particular area with a dye that is capable of binding or conjugating to chitin and emitting fluorescence upon exposure to light. If a chitin-containing organism is present in the treated area, the chitin of the organism will bind or conjugate the dye and, upon exposure to light, the chitin-containing organisms may be visualized and removed. Also provided by the present invention are solutions and suspensions that contain a dye capable of binding or conjugating to a chitin-containing organism and emitting fluorescence upon exposure to light. The solutions and suspensions provided herein may be in the form of a shampoo, cream, lotion or detergent for the detection of chitin-containing organisms present in body hair, on the skin, clothing or the fur of animals.

Abstract: A safety transport box is provided with an inner enclosure configured for releasably engaging specimen collection equipment. The safety transport box further includes an outer enclosure for protectively enclosing the inner enclosure. The inner and outer enclosures are spaced from one another for preventing contact related damage to the specimen collection equipment. Both the inner and outer enclosures are selectively openable for accessing the specimen collection equipment.

Abstract: A carrying case for carrying and organizing medication is disclosed. The carrying case comprises a first compartment and second compartment, with the first and second compartments relatively foldable along a common fold line between an open position and a closed position. The first and second compartments are disposed in face-to-face relationship when the first and second compartments are in the closed position. A plurality of slots are defined in at least one of the compartments, and a plurality of inserts are provided. Each of the inserts is sized for insertion into a corresponding one of the slots, with each of the inserts having at least one closeable chamber. A divider panel is provided, with the divider panel mounted for shiftable movement between a folded position in which the divider panel is disposed over at least one of the compartments and an unfolded position in which the divider panel permits access to the at least one compartment.

Abstract: A safety and emergency kit for deployment in a building and including safety, evacuation, and communication equipment for use in evacuating the building and protecting the user from hazardous conditions during evacuation.

Abstract: A first-aid device for motor vehicles which has an elastic unrollable mat which is used as a carrier for items of first-aid equipment and has an essentially rectangular shape. In order to use existing storage space effectively and, in particular, to obtain a compact structural shape, the mat has a fastener on two longitudinal edges, so that it can be folded-up to form a flexible container. In the process, the fastener connects the longitudinal edges of the mat to form a stable, cylindrical container.

Abstract: An automatic medication dispensing and packaging system comprising a medication dispensing unit having base and door cabinets, the door cabinet rear portion correspondingly and detachably engaged to the base cabinet rear portion, the base cabinets distanced from each other to form a space that allows therein a manual management of the dispensing unit. The manual management includes cassette replacements, tablet filling in the cassettes, and spatial shaft cleaning.

Abstract: The present invention is directed towards a kit to accompany a supply of a long-term use pharmaceutical. The kit includes at least a supply of a long-term use pharmaceutical, printed matter, and a pre-recorded media device. The kit may also include a planner and a reminder tool. The present invention also includes a container for storing at least the supply of the long-term use pharmaceutical, the printed matter, and the pre-recorded media device.

Abstract: A kit is disclosed which includes a blister tray and a package for a small device insertable within the blister tray. The blister tray has at least one medical device contained therein. The package includes a pair of end flaps engageable with the medical device such that the medical device, contained within the blister tray, inhibits the removal of the package from the blister tray. A plurality of openings is provided in the package and cooperates with each other to form a receptacle for a medical device, such as a vessel inverter.

Abstract: A medicine chest comprises a chest body with a plurality of storage compartments. For closing the medicine chest, a displaceable shutting means (24) is provided. This requires substantially less space than doors, for example.

Abstract: A kit containing a complete set of items needed to implant a sustained ocular or intraocular drug delivery system, including, but not limited to, injection devices, topical and injectable medications, surgical instruments, sutures and suturing needles, and eye covers. Provision of the set of items in a kit simplifies preparation for insertion of drug delivery means, reduces the cost of such preparation, reduces the likelihood of errors in preparation or selection of appropriate items during surgery, reduces the complexity of maintenance of sterile conditions, and ultimately reduces the cost of delivering ocular care.

Abstract: CD holders with musical content are within convenient reach in a vehicle armrest, and this convenience is used to advantage for a CD holder commingled with the musical variety, but with a substantial first-aid contents; thus, first-aid treatment in a vehicle is made as readily accesible as reaching for a CD.

Abstract: A kit is disclosed which includes a blister tray and a package for a small device insertable within the blister tray. The blister tray has at least one medical device contained therein. The package includes a pair of end flaps engageable with the medical device such that the medical device, contained within the blister tray, inhibits the removal of the package from the blister tray. A plurality of openings is provided in the package and cooperates with each other to form a receptacle for a medical device, such as a vessel inverter.

Abstract: The present invention describes novel compounds of the formula: (Q)d—Ln—Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.

Abstract: A biological sample collection and storage kit s disclosed that includes a plurality of biological sample storage devices, a plurality of biological sample collection devices configured to collect biological samples for placement into the sample storage devices, identification devices for identifying the contents of the sample storage devices, and a housing including a base portion and a lid portion forming an interior cavity therebetween for accommodating the plurality of biological sample storage devices, the plurality of biological sample collection devices and the identification devices.

Abstract: A connector device is provided that permits two separately stored ingredients to be mixed in and dispensed from the same container. The connector device includes an attachment mechanism for connecting two containers together to permit combining of separately stored ingredients and another attachment mechanism for connecting a dispenser to the container containing the combined ingredients to permit dispensing of the product directly from that container. In a preferred embodiment, a stopper is included in the neck of the first container, the second container including a device for penetrating the stopper. Also disclosed is a method of intermixing products with the connector device.

Abstract: A blanket which is placed over a person to protect the person from flying glass during extrication of the person from a vehicle involved in a collision. The blanket comprises at least one inner layer of pliable cut-resistant material and at least two outer layers of buffer material between which said inner layer is sandwiched so as to provide the feel and body of a blanket. A kit for use by rescue workers includes, in addition to the blanket, gloves for handling the blanket after use, a bio-hazard bag in which the used blanket is placed, and a carrying case for the blanket, gloves, and bio-hazard bag.

Abstract: A barium swallowing kit comprising a primary container and a plurality of individual food containers included in the primary container. Each of the food containers includes a measured amount of a liquid or a solid food of differing consistency to provide variety for testing the patient's swallowing mechanism. A plurality of barium packets are also included in the primary container. Each of the barium packets has a measured amount of barium sulfate for mixing with the food in one of the food containers. Accordingly, the invention provides for a ready-made dosage of barium sulfate to be mixed with an included solid or liquid food substance to facilitate the determination of whether the patient is experiencing an aspiration problem during swallowing.

Abstract: An object of the present invention is to provide a medicine wrapping machine which wraps each administered amount of a medicine in a medicine wrapping sheet, and enables easy opening even by an aged person or a child. The medicine wrapping machine uses a belt-shaped medicine wrapping sheet, and forms a plurality of divided wrapping bags continuous in a state of containing medicines therein and separated at the time of taking the medicines to wrap the medicines. A raw material of the medicine wrapping sheet is a belt-shaped transparent composite plastic sheet which includes a polyethylene terephthalate (PET) sheet or a biaxially oriented polypropylene sheet, and a minute flaw is formed on the polyethylene terephthalate sheet or the biaxially oriented polypropylene sheet.

Abstract: RECEPTACLE FOR HOLDING MEDICAL SUPPLIES A receptacle for holding medical supplies is necessary for a caregiver to quickly and efficiently obtain desired medical supplies within a caregiving room or a caregiving vehicle, such as Emergency Medical Service vehicles, fire engines, or ambulances. Caregiving rooms and vehicles can be small and lack cabinets sufficient to hold certain medical supplies. The present invention's slim structure can be either mounted on a wall, placed on a countertop, on a floor, or on a stand of the caregiving room or vehicle. When the present invention is opaque or clear, the medical supplies contained therein are visible. The receptacle can also be a solid color with the contents and their warning indications depicted on the outer front of the receptacle. A user can conveniently and expediently extract medical supplies through openings on the receptacle by using only one hand since the medical supply containers are restrained by the restraint feature of the receptacle.

Abstract: An apparatus for assisting in the changing of diapers for a baby in the form of a portable diaper caddy. The tray has a base adapted to rest upon a surface. The tray includes multiple selectively sized compartments including a diaper compartment in the tray adapted to contain a plurality of diapers, a pad compartment in the tray adapted to contain a baby changing pad, and a wipe compartment in the tray adapted to contain a plurality of wet baby wipes. A lid covers the wipe compartment, the lid sealing against a top portion of the wipe compartment to prevent evaporation of liquid contained in the wet baby wipes. A handle extends from the tray to allow persons to grasp the tray for carrying the tray.

Abstract: A patient discharge system and method for self-care of a post-surgical drain site by a patient are revealed. The system contains apparatus for at least one dressing change and includes non-latex gloves, measuring cups, gauze pads, adhesive tape remover pads, a pencil, antibacterial soap, tape, belt bags, numbered drain labels, split gauze pads with foam support bars, drainage record cards, a set of step-by-step instructions and a box having a ruler on an inside of the box top. The system includes one set of step-by-step instructions for a medical professional to instruct a patient in the use of the patient discharge system. A copy of the step-by-step instructions is included for acknowledgment by the user and retained by the medical professional for medical records.

Abstract: An enclosed implantable material mixing system is described herein. The system uses an enclosable vial or container into which bone cement mixture may be mixed by agitation. The bone cement mixture may be made of a combination of polymer and liquid monomer, but because of the method of agitation, e.g., shaking the vial and its contents, the ratio of the monomer-to-polymer is critical. A desirable weight ratio of the monomer-to-polymer is about 0.3 to about 1, and more preferably about 0.53 to about 0.63, and is more preferably about 0.57. The vial or container may also include a free-floating, or disassociated, agitator to aid with the mixing process. To prepare the composition, the vial and its contents may be capped and shaken until the mixture dissolves completely. The contents of the vial are then allowed to sit and undergo a solvation process at the end of which the mixture may be shaken again and then poured out for use.

Abstract: A prepackaged diaper changing kit which is compact and convenient to carry and use and which is capable of being both dispensed from a conventional vending machine, as well as being displayed on shelves and sold in conventional retail establishments. A preferred embodiment of this prepackaged diaper changing kit includes a disposable diaper, at least one (1), and more preferably two (2), prepackaged moist baby wipes, a prefolded baby liner, a prepackaged instant hand sanitizer and a prefolded disposable plastic bag. These items are preferably prepackaged together in a durable waterproof outer wrapper, such as an opaque plastic outer wrap film. The prepackaged diaper changing kit in accordance with the present invention provides all of the supplies needed to change a diaper for, for example, a newborn or infant, and, when finished, allows the user to secure and discard the dirty or wet diaper, as well as the used moist baby wipes and other left over packaging materials, in a safe and convenient manner.

Abstract: Disclosed are diaryl piperazines and related compounds of the following Formula: wherein the variables are as defined in the specification. These compounds are selective modulators of capsaicin receptors, including human capsaicin receptors, that are, therefore, useful in the treatment of a chronic and acute pain conditions, itch and urinary incontinence. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds of the invention are also useful as probes for the localization of capsaicin receptors and as standards in assays for capsaicin receptor binding and capsaicin receptor mediated cation conductance. Methods of using the compounds in receptor localization studies are given.

Abstract: A method for preparing both main label and warning label portions for a container useful in dispensing drugs by a pharmacist in which the main label portion contains specific drug or patient information and the warning label portion contains one or more warnings specific to the drug or patient information includes the steps of providing a backing sheet having the main label portion and the warning label portion releasably adhered thereto, printing the drug or patient information on the main label portion and the drug-specific information on the warning label during only one printing pass, and then affixing both the main label portion and the warning label portion to a drug container.

Abstract: A method and system for performing intermittent male catheterization by a patient, a patient's caregiver, or a health care provider are revealed. The system contains apparatus for at least one intermittent male catheterization and includes at least one male catheter, antibacterial soap, a lubricant, step-by step-instructions, and a container, where the above named items are positioned inside the container. The method includes self-care documentation for a medical professional to instruct a user in the use of the system and to keep a record that the instruction of the patient was performed.

Abstract: The invention provides compositions and methods for the convenient compounding of pharmaceuticals. Single and multiple unit of use kits are provided which contain all the necessary components required for preparing a compounded pharmaceutical.

Abstract: In a medication cart apparatus housing a plurality of individual medication bins, the invention provides devices and a method for reducing the risk of nosocomial infection through the use of disposable bin liners. In some applications the bin liners may be color coded for a predetermined use or patient, compartmentalized with dividers, or customized with special labels. The disposable liners may have a tapered form so that multiple liners may be stored in a nested stack to minimize space requirements and to be loaded into a liner dispenser system.

Abstract: A kit for obtaining an endoarterial biopsy sample from a patient comprising: (i) packaging material enclosing one or more kit components; (ii) wherein the kit components comprise one or more of the following: a) an endoarterial biopsy catheter; b) Percutaneous Access Needle; c) Short Introducer Sheath with Dilator & Guidewire; d) Floppy Guidewire; e) Endhole Catheter with inflation syringe; f) Stiff Guidewire; g) Flushing Syringes; h) Long Introducer Sheath with Dilator; i) Biopsy specimen removal tool; j) Biopsy Cassettes; k) Specimen Containers; l) Connective Tubing; m) Vacuum Gauges & Canisters; and, n) Vacuum pump.

Abstract: An anti-splash, anti-spill fluid-holding apparatus is disclosed, comprising: an inner side surface comprising an inner mid section diameter continuing inwardly to an inner upper section diameter which is smaller than the inner mid section diameter; an outer side surface comprising an outer mid section diameter continuing to an outer lower section diameter which is larger than the outer mid section diameter; an inward angle comprising a less than 90 degree angle tangential to any point along the inner side surface from the inner mid section diameter to the inner upper section diameter; an open top circumscribed by the inner upper section diameter; and a base circumscribed by the outer lower section diameter. In a related method, this apparatus is set upon a surgical support surface, filled with antiseptic solution, and a surgical sponge or swab is introduced to absorb some antiseptic solution for cleaning a patent wound or surgical site.

Abstract: An organizational treatment device and method for the treatment of obstructive pulmonary disease comprising both controller and rescue medications such that the need for rescue medication and consequent need for controller medication can be more certainly determined than at present.

Abstract: Methods and apparatus are disclosed for reducing the degradation of heat sensitive components contained in a medical substance during heat sterilization of a heat sterilizable container including a first chamber including a first amount of a first medical substance and a second chamber including a second amount of a second medical substance, the first amount being greater than the second amount. The method includes heating the heat sterilizable container to a first predetermined temperature for sterilizing the first and second medical substances, thermally insulating the second chamber during at least a portion of the heating of the heat sterilizable container to the first predetermined temperature, holding the heat sterilizable container at the first predetermined temperature for a first predetermined time period, and cooling the heat sterilizable container thereafter.

Abstract: The present invention relates to novel thyroid receptor ligands and, more particularly, relates to malonamic acids and derivatives thereof of Formula I, which are useful in the treatment of obesity, overweight condition, hyperlipidemia, glaucoma, cardiac arrhythmias, skin disorders, thyroid disease, hypothyroidism, thyroid cancer and related disorders and diseases such as diabetes mellitus, atherosclerosis, hypertension, coronary heart disease, congestive heart failure, hypercholesteremia, depression, osteoporosis and hair loss. The present invention also provides methods, pharmaceutical compositions and kits for treating such diseases and disorders.

Abstract: A pharmaceutical kit for treating migraine headaches and method of preparing the kit that includes a therapeutically effective dosage of pharmaceutical compounds used in the treatment of migraine headache. The pharmaceutical kit is manufactured with a predetermined number of dosage units of migraine treating pharmaceutical compounds. Additionally the kit provides all components necessary for the administering of the drugs in a safe and convenient manner. An aspect of the pharmaceutical kit may include injections and nasal sprays that are fast acting for relief of the migraine sufferer. A preferred pharmaceutical kit with only oral dosage units of drugs may be provided as an attachment to a water bottle.

Abstract: Packaging 1 for use in the transport of an item through the mail, the packaging comprising first 3 and second 5 components that can be assembled to define a storage cavity for the item to be transported and an opener 11, 13 operable to open the packaging 1, wherein said components 3, 5 cannot be reassembled once said opener 11, 13 has been operated to open the packaging.

Abstract: A kit that is useful for relieving humans, and in particular infants, from discomfort is disclosed. Examples of such discomfort include fever, pain, congestion, skin irritation, and irritability. The kit includes an inner container having a plurality of compartments and at least one product for comforting humans packed in one of the compartments. Optionally, the inner container may be placed inside of an outer container.

Abstract: A surgical kit, for example a percutaneous endoscopic gastrostomy kit, includes a tray having a plurality of recesses formed therein for receiving surgical implements. A substantially rigid accessory item container is received in a container recess defined in the tray. The container is removable from the tray and includes a base member and a lid. A securing device may be configured between the base member and the lid so that the container is reclosable.

Abstract: A surgical kit, for example a percutaneous endoscopic gastrostomy kit, includes a tray having a plurality of recesses formed therein for receiving surgical implements. A substantially rigid accessory item container is received in a container recess defined in the tray. The container is removable from the tray and includes a base member and a lid. A securing device may be configured between the base member and the lid so that the container is reclosable.

Abstract: A prepared kit according to the invention includes a plurality of pre-cut tape strips for securing a medical device such as a catheter, an intravenous needle, tubing, or a similar device to a patient's skin or to a support. Once a medical attendant has inserted a medical device into a patient's skin at an insertion site, the attendant secures the medical device to the patient's skin or to a support at a point spaced from the insertion site by engaging the medical device with a portion of each of the strips. Each of the strips has a biocompatible adhesive on one surface and a non-adhesive portion on the opposite surface, such that medical personnel are able to rapidly and effectively secure the medical device when putting the device into use.