Abstract: Disclosed is a preparation for oral administration which can reduce the residual amount of a medicinal composition and facilitate the swallowing of the medicinal composition. A preparation for oral administration comprises an enclosing member that is formed of an edible film. A medicinal composition is enclosed in the enclosing member. The enclosing member has a wall part. The wall part is formed by rolling the edible film into a tubular shape. The wall part has a part where the edible film overlaps. The part where the edible film overlaps is formed by rolling a single edible film sheet.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.

Abstract: A first aid kit organized with pockets containing first aid and emergency preparedness supplies and equipment and a system for refilling. Each pocket in the kit contains supplies and equipment useful in providing initial care for a particular illness or injury and is quickly identified through textual labels and transparent elements. The pockets are connected into a strip of pockets which is folded to fit within a case. The strip of pockets is easily deployed from the case facilitating rapid and accurate identification, selection, and acquisition of items appropriate for initial care of a particular illness or injury by comprehensive visual presentation of the organizational scheme and the supplies and pieces of equipment themselves.

Abstract: The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.

Abstract: In one embodiment of the invention, a catheter delivery system or kit is disclosed. The kit contains a prosthetic check valve with leaflets cut from filtration screen material with uniform pore size having openings with a dimension inclusively between fifteen and sixty microns. The screen material is made from biocompatible material, such as polyester or polypropylene. One or more outer edges of the leaflet are fused or sealed to prevent fraying of the material and to form a more non-thrombogenic surface. Prosthetic check valves assembled with the leaflets can be collapsed to a diameter of less than or equal to twenty-nine french (29 f), sterilized, and stored in a collapsed state. The compressed or collapsed valve may be sterilized and included as part of a sterile catheter delivery system or kit, ready for minimally invasive implantation without rinsing prior to use.

Abstract: Packaging for dry prosthetic tissue heart valves and their delivery systems includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Dry tissue heart valves and their delivery systems are placed within a primary container such as a rigid tray that limits movement of the components therein. The primary container is placed within a secondary container, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant. A collapsible delivery handle for a surgical heart valve may be provided which reduces the size of the packaging.

Abstract: A kit for promoting the proper sequential oral administration of a pharmaceutically active ingredient and accompanying nutrients, said kit comprising: (a) at least one unit dose of a pharmaceutical active to be given continuously on a frequency of once a week, twice a week, once every two weeks, twice a month, or once a month; (b) at least one unit dose of a nutrient to be given subsequent to the active dose administration; and (c) a blister card individually and releasably containing the unit doses; wherein said unit doses of pharmaceutical active and nutrient are arranged horizontally or vertically in order of their use across the blister card is useful for aiding in patient understanding and complying with dosage regimens wherein the active ingredient is administered on a continuous frequency other than daily and the nutrient is administered on the days in between the days the active ingredient is administered.

Abstract: The invention relates a pharmaceutical composition comprising a combination of (i) the AT 1-antagonist valsartan or a pharmaceutically acceptable salt thereof and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically acceptable carrier and to a method for the treatment or prevention of selected conditions or diseases.

Abstract: An apparatus for preparing a pharmaceutical for transient application includes a tray having a sealed compartment, a vial of an ophthalmic formulation of mitomycin-C, a diluent carrier containing sterilized water, and a syringe that are all contained together in a single package. The component parts of the apparatus are used together to reconstitute the contents of the vial with the water in the diluent carrier, and then draw the reconstituted drug into the sealed compartment of the tray by a suction force produced by the syringe. In the tray compartment, the reconstituted drug is absorbed in an absorbent pad. The tray is opened to remove the pad and the absorbed drug from the tray compartment for use of the pad in transient application of the drug.

Abstract: A dental care promotional kit includes a housing, a dental care set, and a promotion tool. The housing has a receiving cavity, a reflective windows formed on one of the front promotional panel and the rear promotional panel, and at least one promotional zone formed on the housing. The promotion tool is retrievably disposed in the receiving cavity of the housing, and comprises a promotional member and a reflective element attached on the promotional member, wherein the promotional member further has a promotional section formed thereon for allowing promotional materials to be printed on the promotional section, and is capable of being taken out from the receiving cavity, such that a user is able to freely retrieve the dental care set for performing basic dental care while being imparted with business goodwill shown on the promotion tool and the promotional zone.

Abstract: Bioprosthesis having an implantable braided or woven construct with a plurality of collagen-derived fibers interlocked or interlaced together. The braided or woven constructs can be flexible and resorbable. The braided or woven constructs can have the dynamic flexibility, tensile strength and stiffness suitable for tendon or ligament repairs. The braided or woven construct may be used for ulnar collateral ligament reconstruction.

Abstract: The present invention relates to a hygroscopic matrix based formulation, a process for the preparation thereof and its use in the treatment of diseases.

Abstract: A method for positioning a guide element in a patient and a kit for use in the method. In one embodiment, the method involves transorally inserting an endoscope into a patient's stomach. An incision site is externally indicated by transilluminating the stomach and abdominal walls of the patient from within the stomach. Next, a scalpel incision is made at the indicated incision site, and an access needle is inserted into the incision, the proximal end of the access needle remaining external to the patient and the distal end of the access needle extending into the patient's stomach. The stylet of the access needle is then removed from the patient while keeping the cannula in place. Next, the distal end of a grasping tool is inserted through the cannula and into the patient's stomach. The looped leading end of a pullwire is then inserted through the endoscope and into the stomach. The tool is then manipulated until a distal hook on the tool catches the looped leading end.

Abstract: A first aid kit organized with pockets containing first aid and emergency preparedness supplies and equipment and a system for refilling. Each pocket in the kit contains supplies and equipment useful in providing initial care for a particular illness or injury and is quickly identified through textual labels and transparent elements. The pockets are connected into a strip of pockets which is folded to fit within a case. The strip of pockets is easily deployed from the case facilitating rapid and accurate identification, selection, and acquisition of items appropriate for initial care of a particular illness or injury by comprehensive visual presentation of the organizational scheme and the supplies and pieces of equipment themselves.

Abstract: A system for incontinence maintenance and method employed, of which the system is useful in incontinent care. A plurality of products suitable for use in an incontinence maintenance event are provided in a configuration stacked in the order of anticipated use of individual ones of the products, the first product anticipated for use being uppermost in the stack. A container is provided having a bottom compartment carrying the stack and a top compartment defining a flap extending from the bottom compartment. The container includes means for defining an opening in the bottom compartment to access the stack of goods and for accepting soiled goods therein, and means for resealing the bottom compartment to contain the soiled goods.

Abstract: A tape container aid kit includes a cylindrical spool having substantially circular first and second spool edges longitudinally separated by a spool sidewall defining a spool circumference. An elongate piece of adhesive-backed tape is coiled around the spool circumference. A containing chamber, cooperatively defined by first and second end coverings and the spool sidewall, is wholly enclosed when both of the first and second end coverings are spanning the spool sidewall. At least one of the first and second end coverings is configured to selectively allow access to the containing chamber from outside the tape container aid kit. A plurality of accessory items are located inside the containing chamber. Each of the accessory items bears a categorical relationship to a type of the adhesive-backed tape, such that the accessory items and the adhesive-backed tape collectively form a tape container aid kit of a given categorical type.

Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a ?-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

Abstract: The invention provides a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering an effective amount of a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazine has the formula set forth in the specification. The invention also provides a method of modulating the cytoskeleton of an endothelial cell in an animal. The method comprises administering an effective amount of a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazine has the formula set forth in the specification. The invention further provides a kit. The kit comprises a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal, wherein the diketopiperazine has the formula set forth in the specification.

Abstract: Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type.

Abstract: A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.

Abstract: The invention provides a method of treating comorbid premature ejaculation and erectile dysfunction. In particular, the method comprises administering an effective amount of a tramadol material and an effective amount of a phosphodiesterase inhibitor. The invention also provides a pharmaceutical composition comprising a pharmaceutically-acceptable carrier, a tramadol material and a phosphodiesterase inhibitor. The invention further provides a kit comprising a tramadol material and a phosphodiesterase inhibitor.

Abstract: The present invention relates to a pattern coated pressure sensitive label assembly for use in preserving patient privacy in medical treatment bag applications. The label assembly utilizes specific zones and areas to create removable sections that will permit areas containing patient information to be separated from the remainder of the label which remains with the treatment bag during disposal.

Abstract: A system and method for assisting casualties, categorizing survivors, and communicating pertinent casualty and survivor information to external emergency response teams during a crisis situation. A kit may be provided that comprises a variety of emergency medical supplies, instructional casualty treatment information, and a plurality of casualty placards. Able-bodied survivors with no medical training may use the kit and its contents to properly prioritize and provide basic emergency medical assistance to help reduce casualty mortality during a crisis situation. Instructions and method steps contained within each kit teach each user to first fortify a safe haven, attended to casualty bleeding issues, attend to casualty airway issues, place casualties in a recovery position while continually reassuring and reassessing the casualties, and finally notifying or otherwise communicating casualty number and status to emergency responders.

Abstract: The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for the treatment of stroke, TBI or SCI. DV is also referred to as endorepellin in the art. This application also provides compositions and combination therapies for the treatment of stroke, TCI and/or SCI. Another aspect of the invention provides methods of restoring motor function in subjects having neurological damage arising from a stroke, TBI or SCI.

Abstract: A tray for organizing various objects, e.g., medications, their receptacles and medical implements, that are needed in a typical nursing task is provided. The tray is advantageously constructed to balance all the objects during transport and during use such that its contents are prevented from toppling over in motion or in station.

Abstract: In order to improve a surgical screw container comprising a receiving part and a closure part mounted thereon so as to be movable, wherein the receiving part has at least two screw receptacles for accommodating at least two bone screws, wherein the closure part can be brought relative to the receiving part into at least one closure position, in which none of the screw receptacles is accessible for the introduction or removal of a bone screw, such that any loss of screws from the screw container can be practically ruled out it is suggested that the closure part can be brought from the at least one closure position into at least two removal positions, in each of which only a single screw receptacle is accessible for the introduction or removal of a single bone screw.

Abstract: Temporary tattoo removal devices for temporarily covering and concealing tattoos include an opaque tattoo removal device or a releasable coating layer that is configured to adhere to a user's skin to cover and conceal tattoos. The color of the opaque tattoo removal device or releasable coating layer matches the skin tone of the user's such that the tattoo removal device or releasable coating layer is nearly invisible when applied.

Abstract: This invention relates to benzoyl peroxide products for skin treatment, and more particularly to a kit containing a benzoyl peroxide product and a topical moisturizing product. In one embodiment the kit contains BenzaClin® brand clindamycin-benzoyl peroxide gel and Viscontour® brand hyaluronic acid serum.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: A post-surgical accessory convenience kit, or PACK, and associated devices and methods that allows communication of a patient's post-operative needs and regimens. The PACK and associated devices allows monitoring and remote transmitting of a patient's needs and regimens.

Abstract: A medication kit includes a plurality of individual non-prophylactic, non-urgent care symptomatic treatments configured to treat the symptoms of a pre-existing medical condition such as pregnancy. The treatments include a combination of pharmaceutical treatments and non-pharmaceutical treatments corresponding to particular symptoms often associated with the pre-existing condition. Each of the pharmaceutical treatments are configured for mutually independent dosage, and are predetermined by an authoritative organization such as the Food and Drug Administration to be safe for use at the mutually independent dosages, in combination with one another by otherwise healthy patients having the pre-existing medical condition, without expectation of adverse side effects.

Abstract: A catheter assembly is disclosed comprising a catheter and a receptacle enclosing said catheter. The receptacle has a first part and a second part, which parts are foldable over each other. Further, at least one sticky adhesive area is arranged on the surface of one of the parts of the receptacle in such a way that the sticky adhesive area is covered by the other part when the receptacle is in a folded disposition, and exposed to the environment when the receptacle is in an unfolded disposition.

Abstract: A back support has front, rear, bottom, top and side edges. A box has a rear face formed coextensive with the back support, a front face, a bottom face, and side faces. A rectilinear chamber is formed by the front, rear, bottom and side faces of the box and has an open top for receiving and supporting medication containers on the bottom face of the box for easy access and removal. The chamber is formed with vertically oriented recesses on the front and rear faces of the box. A plurality of rectangular divider panels with edges removably received within the recesses divide the chamber into sections adapted to separate the containers received and supported in the chamber. The panels are repositionable as a function of the size and number of the containers within the chamber.

Abstract: The present invention provides methods of treating fibromyalgia or other diseases or conditions causing widespread pain and/or fatigue. In particular, the invention provides pharmaceutical compositions comprising droxidopa alone, or in combination with one or more further active agents, that can be used in the inventive methods. The methods of treatment can comprise treating, preventing, reducing, or eliminating a variety of symptoms recognized as indicative of fibromyalgia, such as chronic pain, allodynia, hyperalgesia, fatigue, sleep disturbance, and depression.

Abstract: Provided herein are methods for treating and/or preventing a cancer or a tumor syndrome in a patient, comprising administering an effective amount of a TOR kinase inhibitor to a patient having cancer or a tumor syndrome, characterized by a LKB1 and/or AMPK gene or protein loss or mutation.

Abstract: A transdermal patch container (10) that includes a container body (16), a first compartment (24), and a second compartment (28) is disclosed. One or more first transdermal patches (34) may be stored in the first compartment (24). One or more second transdermal patches (36) may be stored in the second compartment (28). The first transdermal patches (34) differ from the second transdermal patches (36) in at least one respect. A number of features may be incorporated to reduce the potential of being able to withdraw second transdermal patches (36) out of the second compartment (28). For instance, second transdermal patches (36) may be required to be directed through a slot (44) to enter a second compartment (28i). A flap (66) may be positioned below such a slot (58) within a second storage compartment (28ii). A plurality of vertically spaced or staggered flaps (96) may be positioned within a second storage compartment (28iv).

Abstract: Provided herein are compositions and methods using stem/progenitor cells in a therapeutic approach for treatment of or promotion of healing of acute and chronic wounds.

Abstract: A portable carrying case is described to hold medicine vials during travel, doctors' visits, etc. The case includes an open-topped box with a hinged lid and attachment means to secure the lid to the box. The case further includes a vial support platform, which may be the upper surface of the box, or a separate platform attachable to the box bottom wall. The platform has a plurality of spaced, parallel divider walls having lower edges attached to the support surface and upper edges. The divider walls have aligned left holes and aligned right holes. An elastic cord is slidable through aligned holes to cord ends outside an end divider wall. A cord lock is used to adjust the length of the cord. The support surface, walls and cord form a plurality of adjustable vial receiving compartments, with the force on each vial being equal regardless of differences in vial sizes.

Abstract: A simplified paracetamol solution for an injectable and ready-to-use preparation is only composed of paracetamol, bi-distilled water and a buffer agent, the formulation having a maximal paracetamol concentration of 1 g/100 ml, a pH between 5.5 and 6.5 and an oxygen content inferior to 0.2 ppm. A method for preparing and packaging such a solution and a device for packaging such a solution are also disclosed.

Abstract: The present invention relates to a packaging system for airway devices that permits their rapid access. In particular, the packaging system is capable of maintaining the device in storage under sterile conditions, yet be capable of facilitating rapid unpackaging and use.

Abstract: Trays comprising a base have a plurality of axial slots adapted to receive buffer or other medical solution containers within the slots. A spring or other compression element at the bottom of the slot is configured to engage a plunger at the bottom of the solution container when present in the slot so that pressure is applied to the contents of the container in order to stabilize the contents while the containers are sterilized at an elevated temperature.

Abstract: In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any condition caused by dysfunctional cells, e.g., mucositis therapies (e.g., for oral mucositis; digestive mucositis; esophageal mucositis; intestinal mucositis). In alternative embodiments, the invention provides cytoprotection products that may be used either alone or in combination with other medical therapies such as cancer chemotherapies and radiation therapies.

Abstract: The present invention relates to a kit for whitening teeth and a kit for fabricating a dental apparatus and/or denture without visiting the dentist or stomataologist.

Abstract: The present disclosure relates to medical packaging for the accommodation of medical supplies. The medical packaging discussed herein has a plurality of panels, including a first panel, a second panel, and a third panel, that are releasably secured together to establish a first sterile environment between the first panel and the second panel for the retention of a first medical supply, and a second sterile environment between the second panel and the third panel for the retention of a second medical supply. The panels are configured for relative movement such that movement of the first panel relative to the second panel reveals the first medical supply without compromising the second sterile environment, and movement of the second panel relative to the third panel reveals the second medical supply. The panels are arranged for sequential separation in accordance with the steps of the procedure in which the medical supplies are employed.

Abstract: An immunogenic composition or vaccine, and method of treatment are provided by the present invention. The immunogenic composition is useful for treating, preventing, and lessening the severity of clinical symptoms associated with disease-causing organisms in swine, utilizing one or more Porcine Teschovirus antigen(s) along with an antigen of the other disease-causing organism in swine and a pharmaceutically acceptable carrier.

Abstract: A package for feminine hygiene articles. The package includes a refillable cabinet having a front, a back, a top, a bottom, a first side, a second side, and a frame, the frame forming at least one feminine hygiene storage cavity having a frontward facing opening, and a plurality of replaceable drawers each containing a plurality of feminine hygiene articles and being slidingly installed within the feminine hygiene storage cavity.

Abstract: The present invention provides methods and compositions for increasing the rate of nail growth in mammals, especially humans, using thyromimetic compounds.

Abstract: A compartmentalized protective case houses a portable electronic device and personal care items that are organized and held securely therewithin. The compartmentalized protective case has a major compartment for receiving and housing an electronic device such as a smart phone, cellular phone, music player, or other digital media device. At least one cell compartment constructed within the case receives and houses personal care items removably integrated therein. Personal care items can include at least one interchangeable replacement cell containing beauty items, cosmetics, hygienic items, oral care products such as floss or breath strips, medications, vitamins, breathe fresheners and/or health care products. A second cell compartment is preferably provided as a removable pouch or may contain a restraining system for holding identification cards, currency, visa or bank cards, and/or keys.

Abstract: A compartmentalized protective case houses a portable electronic device and personal care items that are organized and held securely therewithin. The compartmentalized protective case has a major compartment for receiving and housing an electronic device such as a smart phone, cellular phone, music player, or other digital media device. At least one cell compartment constructed within the case receives and houses personal care items removably integrated therein. Personal care items include a plurality of interchangeable replacement cells containing beauty items, cosmetics, hygienic items, oral care products such as floss or breath strips, medications, vitamins, breathe fresheners and/or health care products. A second cell compartment is preferably provided as a removable pouch or restraining system for holding identification cards, currency, visa or bank cards, and/or keys.

Abstract: A comprehensive organizational system for managing medical records for an individual patient and a method for managing the dispensation of multiple medications. The method includes a set of symbols indicating the time of day the medication should be administered in accordance with the prescription instructions and a storage system for duplicate prescription labels corresponding to the prescription labels on the prescription containers. The dosage schedule and amount are translated into the symbols which are applied to each duplicate prescription label. Medications are dispensed to the patient in accordance with the symbols applied to the duplicate prescription labels.